JP5527461B2 - Drug packaging device - Google Patents

Description

  The present invention relates to a medicine packaging device for packaging medicines such as tablets and powders including capsule tablets.

  Various types of drug packaging devices have been provided that wrap medicines such as tablets and powders one by one (one package) based on a prescription to create a continuous medicine package. Among them, there is one that uses a roll in which an elongated packaging sheet that is folded in advance in the longitudinal direction is wound. In general, in the packaging section of this type of drug packaging apparatus, a packaging sheet is supplied from a roll, and necessary information is printed by a printing section. Then, the packaging sheet is opened from a folded state and inserted into this opening. One package of drug is introduced from the nozzle part of the hopper. Subsequently, the packaging sheet is sealed (heat-sealed) so as to confine the drug in the heat seal portion (see, for example, Patent Documents 1 to 4).

  When the drug packaging device is first started up or when the roll is replaced, the packaging sheet unwound from the roll must be routed to the heat seal part via the nozzle part or printing part of the hopper, and then the medicine packaging operation must be started. is there. In other words, when replacing the roll, the packaging sheet having a length from the printing unit to the heat seal unit (usually a length corresponding to about 5 to 6 packages) functions only for routing. The medicine packaging must be discarded without being used, which is not preferable from the viewpoint of cost. Moreover, if the path | route of the packaging sheet from a printing part to a heat seal part is long, size reduction of a chemical | medical agent packaging apparatus cannot be implement | achieved. Therefore, if the length of the path from the printing unit to the heat seal unit can be shortened, the waste of the packaging sheet accompanying roll replacement or the like can be eliminated, and the apparatus can be downsized. However, it is not possible to prevent wrinkles generated in the packaging sheet at the heat seal portion by simply shortening this path. The generation of wrinkles is particularly noticeable when the heat sealing part employs a method of heat-sealing the packaging sheet by passing between a pair of heater rollers.

  45 and 46, the folded folded packaging sheet 1100 is spread in a V shape by the unfolding guide 1106, and reaches the heater roller 1102 of the heat seal portion via the nozzle portion 1101 of the hopper. The heater roller 102 performs a horizontal seal 1103 that seals the opening edge of the packaging sheet 1100 in the longitudinal direction and a vertical seal 1104 that seals from the opening edge to the crease so as to cross the packaging sheet 1100. When an imbalance occurs in the tension acting on each of the two-folded sheets 1100, one of the two-folded sheets 1100 bends with respect to the other, and this bending causes a flange 1105 extending in the longitudinal direction in the vicinity of the lateral seal 1103. Likely to happen. This wrinkle 1105 is caused by swelling of the packaging sheet 1100 when a medicine is introduced, a difference in tension between a portion where the horizontal seal 1103 of the packaging sheet 1100 is formed, and a portion where the vertical seal 1104 is formed, and the like. it is conceivable that. When such wrinkles 1105 occur, the airtightness is reduced due to a seal failure, which causes contamination (contamination) of medicines between adjacent prescriptions.

  Patent Documents 1 and 2 disclose a triangular plate-shaped development guide 1106 having a constant thickness and a development guide 1106 having a substantially triangular pyramid shape configured by a plurality of planes. However, when the unfolding guide 1106 having these shapes is employed, the above-described ridge 1105 is unavoidable on the packaging sheet 1100 if it is disposed close to the printing unit in order to shorten the length of the path from the printing unit to the heat seal unit. Will occur.

  Further, in this type of medicine packaging device, there is a problem that medicine (particularly powder) supplied from the powder supply unit or tablet supply unit to the packaging unit remains attached to the hopper and causes contamination. In order to prevent this drug residue, it is known that a hopper is intermittently hit by a solenoid-driven mechanism to apply an impact, thereby smoothly moving the drug in the hopper. However, even if the hopper is hit intermittently, it is not always possible to effectively prevent the drug from adhering to the hopper. Further, the sound generated when the striking mechanism strikes the hopper is uncomfortable for the worker, and the worker may misunderstand that the striking sound is caused by a failure of the apparatus. For example, in a small-scale dispensing pharmacy or the like, the hitting sound of a hopper may reverberate in a room, and may be uncomfortable not only for workers but also for patients. In consideration of discomfort given to the patient, in order to shorten the hitting time of the hopper as much as possible, the hitting by the solenoid mechanism is generally executed only for a short time after the medicine is discharged from the nozzle part below the hopper. However, such an extremely short impact is not desirable from the viewpoint of effective prevention of drug residue. As described above, this type of known drug device cannot effectively prevent drug residue in the hopper while reducing discomfort for the operator and patient.

JP 2004-189336 A JP 2004-284663 A JP 2004-238026 A JP 2002-19737 A

  It is an object of the present invention to reliably prevent drug residue in a hopper without causing discomfort or malfunction occurrence in a drug packaging device.

The present invention provides a medicine package comprising a medicine introduction part for introducing a medicine from an opening of an elongated packaging sheet folded in two along the longitudinal direction, and a heat seal part for sealing the packaging sheet so as to confine the introduced medicine. In the apparatus, an unfolding guide for unfolding the folded package sheet to form the opening, and the medicine introduction part has an introduction opening at which a medicine is introduced at an upper portion, and the folded folded packaging sheet A hopper having a nozzle portion at a lower portion thereof for introducing the medicine into the packaging sheet, a first vibration applying mechanism for applying vibration to the hopper, and a second for applying vibration to the deployment guide. And a vibration applying mechanism .

By applying vibration to the hopper with the first vibration application mechanism, it is possible to effectively prevent the drug (particularly powder) from adhering and remaining on the hopper and to eliminate contamination. Compared with the sound generated when hitting the hopper, the sound generated by applying the vibration has a low volume, does not give the operator unpleasant feeling, and the operator does not mistake the occurrence of the failure. By applying vibration to the deployment guide with the second vibration application mechanism, the movement or flow of the medicine (especially powdered medicine) in the folded packaging sheet becomes smooth, so that the medicine adheres to the hopper and remains. Can be prevented more reliably.

  Specifically, the first vibration application mechanism includes a first vibration generation source, and a holding structure that holds the first vibration generation source and the hopper.

  The hopper includes at least one inclined surface extending obliquely downward from the charging opening toward the nozzle portion, and the holding structure has a movement direction in which the medicine moves by gravity on the inclined surface and a gravity direction. It is preferable that an angle formed by the major axis of the elliptical orbit of vibration of the hopper and the moving direction in which the powdered drug moves by weight on the inclined surface is an acute angle.

  By giving such vibration of the trajectory, it is possible to increase the movement speed of the drug on the inclined surface of the hopper while reliably preventing the drug from remaining due to adhesion, and more efficiently introduce the drug from the nozzle part into the opening in the packaging sheet part. it can.

  In order to realize this track, for example, the holding structure includes a hopper holding portion that holds the hopper and a vibration source holding that holds the first vibration generation source provided on one end side of the hopper holding portion. And a leaf spring portion extending from the hopper holding portion obliquely downward so that the lower end side is fixed and the lower end side is closer to the vibration source holding portion.

  Preferably, the heat seal part includes a heat seal member that sandwiches the packaging sheet, and a controller that operates the first and second vibration generation sources for a predetermined time when the heat seal part is in a predetermined state. Further prepare.

  In particular, the controller determines whether the medicine of the medicine package being created is a powder or a tablet based on the input prescription information, and if the medicine package being created is the powder, the tablet The time for operating the first and second vibration generating sources is set longer than in the case of (1).

  With this configuration, it is possible to more reliably introduce a powder that is more likely to adhere to the hopper than the tablet into the packaging sheet.

  When the controller determines whether there is a medicine package for packaging only the tablet after the medicine package for packaging the powder in the same prescription based on the inputted prescription information, the medicine package for the tablet only is being created. Maintains the first and second vibration sources in a stopped state.

  With this configuration, contamination due to powder remaining in the hopper can be more reliably prevented.

  If a medicine is mixed in a so-called loss bag, it will flow out into the apparatus when it is cut downstream of the heat seal part, and contamination will occur. Accordingly, when the controller determines that an empty medicine package that does not package the medicine is being created based on the input prescription information, the controller can maintain the first and second vibration generation sources in a stopped state. preferable.

  Preferably, a front side holding part that is arranged in a storage chamber in the apparatus main body and extends to the front side of the apparatus main body, and a side surface side holding part that extends from one side end side of the front side holding part to the back side, A holding frame having a rotation connecting portion that rotatably connects the other side end of the front holding portion to the apparatus main body, and the sheet supply unit is unwound from the roll. A sheet guide mechanism for guiding the packaging sheet, wherein the roll, the printing unit, and a part of the sheet guide mechanism are disposed on the side-side holding unit of the holding frame, and the remaining of the sheet guide mechanism The portion, the deployment guide, the drug introduction part, and the heat seal part are arranged on the front side holding part of the holding frame.

  Since the holding frame includes a front side holding portion and a side surface side holding portion extending from the front side holding to the back side, the sheet supply unit, the unfolding guide, the heat seal unit, and the printing unit are arranged in a compact manner so that the space in the storage chamber is Available. In other words, the apparatus can be reduced in size. On the other hand, if the holding frame is rotated around the rotation connecting part, the roll of the transport sheet and the printing part can be moved to the front side of the apparatus main body and easily accessed from the outside of the apparatus main body. Workability of various operations such as replacement and maintenance of the printing unit is improved.

In the medicine packing apparatus of the present invention, by providing a vibration applying mechanism for applying vibration to the hot path, without causing discomfort or failure false, it is possible to prevent the drug remaining in the hopper.

The perspective view seen from the front side which shows the appearance of the medicine packaging device concerning a 1st embodiment of the present invention (the sealing cover is in the middle position between a closed position and an open position). The perspective view seen from the front side which shows the appearance of the medicine packaging device concerning a 1st embodiment of the present invention (the blockade cover is in a closed position). The front view of a control panel. The block diagram which shows the structure of the chemical | medical agent packaging apparatus which concerns on 1st Embodiment of this invention. The fragmentary sectional view of the tablet supply unit in the state where the shutter was closed. The fragmentary sectional view of the tablet supply unit during shutter opening. The fragmentary sectional view of the tablet supply unit in the state where the shutter was opened. The perspective view which shows a tablet accommodating part. The elements on larger scale of FIG. The fragmentary sectional view of the tablet supply unit of the state which closed the sealing cover and the protective cover. The fragmentary sectional view of the tablet supply unit of the state which opened the sealing cover. The fragmentary sectional view of the tablet supply unit of the state which closed the sealing cover. The fragmentary sectional view of the tablet supply unit in a state where the sealing cover is half open. The top view which shows the tablet supply unit of the state which open | released the sealing cover. The top view which shows the tablet supply unit of the state which closed the sealing cover. The disassembled perspective view of a tablet delivery part. The flowchart for demonstrating operation | movement of a tablet supply unit. The perspective view which looked at the packaging unit from the side upper part. The perspective view which looked at the packaging unit from the front upper direction. The front view of a packaging unit. The side view of a packaging unit. The top view of a packaging unit. Sectional drawing which shows the chemical | medical agent packaging apparatus in the state which has a packaging unit in an accommodation position. Sectional drawing which shows the chemical | medical agent packaging apparatus of a state which has a packaging unit in an extraction position. The perspective view which looked at the expansion | deployment guide from upper direction. The perspective view which looked at the expansion | deployment guide from the back side. The top view of an expansion | deployment guide. The front view of an expansion | deployment guide. The side view which shows the relationship between an expansion | deployment guide and a packaging sheet. The side view which shows the relationship between an expansion | deployment guide and a packaging sheet. The fragmentary perspective view which shows the packaging unit of the chemical | medical agent packaging apparatus which concerns on 2nd Embodiment of this invention. The fragmentary perspective view which shows the packaging unit of the state which removed the hopper. The partial front view which shows the packaging unit of the state which removed the hopper. The typical front view which shows a hopper side vibration application mechanism. The partial perspective view which shows the expansion | deployment guide side vibration application mechanism. The partial cross section side view which shows the expansion | deployment guide side vibration application mechanism. The schematic diagram which shows an example of the presence or absence of operation | movement of the vibration application mechanism for every medicine package. The schematic diagram for demonstrating the presence or absence of operation | movement of the vibration application mechanism in case there are two loss bags. The schematic diagram for demonstrating the presence or absence of operation | movement of the vibration application mechanism in case there are three loss bags. The fragmentary perspective view (state which attached the hopper) which shows the packaging unit of the chemical | medical agent packaging apparatus which concerns on 3rd Embodiment of this invention. The fragmentary perspective view which shows the packaging unit of the chemical | medical agent packaging apparatus which concerns on 3rd Embodiment of this invention (state which removed the hopper). The top view which shows the packaging unit of the state which removed the hopper. The right view which shows the packaging unit of the state which removed the hopper. Sectional drawing in the XXXVIII-XXXVIII line of FIG. The partial perspective view which shows the expansion | deployment guide side vibration application mechanism. The right view of the packaging unit with which the chemical | medical agent packaging apparatus which concerns on 4th Embodiment of this invention is provided. The perspective view which looked at the expansion | deployment guide from upper direction. The top view of an expansion | deployment guide. The front view of an expansion | deployment guide. A side view of a deployment guide. The schematic diagram which shows the structure of the expansion guide periphery in the conventional chemical | medical agent packaging apparatus. The typical top view which shows the structure of the nozzle part periphery of the hopper in the conventional chemical | medical agent packaging apparatus.

(First embodiment)
1 and 2 show a medicine packaging device 1 according to an embodiment of the present invention.

(overall structure)
The medicine packaging apparatus 1 includes a tablet supply unit 2, a powder supply unit 3, a packaging unit 4, and a medicine discharge unit 5 through which a packed medicine is discharged. The tablet supply unit 2 and the powder supply unit 3 are provided on the upper surface side of the housing 6. On the other hand, the packaging unit 4 is disposed in a storage chamber 7 in the housing 6. The front opening of the housing 6 is covered with a single door type openable / closable cover 8 except for the medicine discharge part 5 so as to be opened and closed. If this cover 8 is opened, the operator can access the packaging unit 4 in the storage chamber 7. The form of the cover 8 is not particularly limited, and may be another form such as a double door.

  A control panel 9 shown in FIG. 3 is provided on the upper surface of the housing 6. Referring also to FIG. 4, the operations of the tablet supply unit 2, powder supply unit 3, and packaging unit 4 are input from the control panel 9, sensors 27 and 28 of a sealing cover (hand support member) 25 described later, It is controlled by the controllers 11, 12, and 13 based on the inputs of the other sensors 29 and 30 and the prescription information input from the outside. In this embodiment, the tablet supply unit 2 is controlled by the controller 11, the powder supply unit 3 is controlled by the controller 12, and the packaging unit 4 is controlled by the controller 13. However, the structure which controls two or more units among the tablet supply unit 2, the powder supply unit 3, and the packaging unit 4 with a common controller is also possible.

(Tablet supply unit)
Hereinafter, the tablet supply unit 2 will be described with reference to FIGS. First, referring to FIG. 5A to FIG. 5C, the tablet supply unit 2 includes a fixed tablet storage portion 22 (in this embodiment, a part on the upper surface side of the housing 6) in which a plurality of tablet storage baskets 21 are provided in a matrix shape. And a tablet dispensing unit 23 that automatically and sequentially takes out one package of tablets supplied manually to each tablet container 21 and supplies it to the packaging unit 4.

  Referring to FIGS. 1, 2, 6, and 7, in the tablet storage portion 22 in the present embodiment, the same shape of tablet storage baskets 21 has four rows in the front-rear direction (row direction) and the horizontal direction (row direction). ) Is provided in a total of 28 in 7 rows. The tablet storage unit 22 includes a plurality of first partition walls 24a that separate the tablet storage baskets 21 adjacent in the row direction and a plurality of second partition walls 24b that partition the tablet storage baskets 21 adjacent in the column direction. Each tablet container 21 is partitioned by the first and second partition walls 24a and 24b. Each tablet container 21 is open at both upper and lower ends. The upper end opening 21a functions as an opening for an operator to put tablets into the tablet storage bowl 21 manually. The lower end opening 21b located on the opposite side of the upper end opening 21a functions as an opening through which the tablet accommodated in the tablet accommodating bowl 21 is sent to the tablet dispensing unit 23.

  Referring to FIGS. 1, 2, and 6, the tablet container 22 includes a generally sheet-shaped or plate-shaped sealing cover 25 and a generally sheet-shaped or plate-shaped protective cover 26. The sealing cover 25 and the protective cover 26 are rotatably attached to the upper surface of the tablet housing part 22. Specifically, two pin mechanisms (rotating support mechanisms) 100A and 100B are provided further to the rear side than the rearmost row of tablet accommodating bowls 21, and are blocked by the pin mechanisms 100A and 100B. The base end sides of the cover 25 and the protective cover 26 are rotatably supported. The sealing cover 25 is disposed on the front side of the protective cover 26, and is positioned below the protective cover 26 when both the sealing cover 25 and the protective cover 26 are closed (see FIG. 8A).

  When the protective cover 26 is in the open position, it is manually opened around the pin mechanisms 100A and 100B, thereby opening the sealing cover 25 from the tablet containing portion 22 (FIGS. 8B and 9A) It can move to the closed position (FIGS. 8C and 9B) placed on the portion 22. As shown in FIGS. 8B and 9A, if the sealing cover 25 is in the open position, the upper end openings 21a of all the 28 tablet storage bowls 21 are opened, and the tablets can be put into all the tablet storage bowls 21. On the other hand, as shown in FIG. 8C and FIG. 9B, when the sealing cover 25 is in the closed position, the upper ends of the seven tablet storage baskets 21 constituting the rearmost row of the tablet storage baskets 21 in four rows and seven rows. The opening 21 a is blocked by the blocking cover 25. As a result, tablets can be put into only 21 tablet storage baskets 21 in 3 columns and 7 rows. In other words, the width of the sealing cover 25 is set so as to close the tablet housing rods 21 in the rearmost row at the closed position.

  When the sealing cover 25 is in the closed position (FIG. 8C, FIG. 9B), tablets can be stored in the tablet storage basket 21 in 3 rows and 7 rows (21), so the dosing time is a multiple of 3, that is, 3 minutes ( In the case of morning, noon, and evening), it is possible to efficiently carry out the manual operation of the tablets into the individual tablet storage bowls 21 without causing any insertion error. On the other hand, when the sealing cover 25 is set to the open position (FIGS. 8B and 9A), the tablets can be stored in the tablet storage basket 21 in 4 rows and 7 rows (28), so the dosing time is a multiple of 2, that is, In the case of minutes 2 (morning, evening) or minutes 4 (morning, noon, evening, before going to bed), the manual operation of tablets to the individual tablet container 21 is performed efficiently and reliably without causing an error. it can.

  Referring to FIG. 9A, on the upper surface of the tablet storage unit 22, the first package number display unit 101 is located on the rear side (front side of the pin mechanisms 100A and 100B) behind the row of the rearmost tablet storage baskets 21. Is provided. Referring to FIG. 9B, a second package number display unit 102 is provided on the top surface of the sealing cover 25 in the vicinity of the tip. 9A and 9B, as conceptually indicated by a two-dot chain line, in the tablet manual operation, generally, the tablet storage basket 21 in the foremost (front) column of the rightmost row is arranged in the column direction. Into the rear side (back side) in order. In the package number display portions 101 and 102, when the tablets are put into the tablet container 21 in this order, all the tablet containers 21 constituting each row (four in FIG. 9A and three in FIG. 9B). The number of packages when a tablet is loaded is displayed. Specifically, a multiple of 4 from 4 to 28 is displayed on the package number display unit 101 on the upper surface of the tablet storage unit 22, and 3 to 21 is displayed on the package number display 102 on the upper surface of the sealing cover 25. Multiples of up to 3 are displayed. By referring to these package number display units 101 and 102, it is possible to further increase the efficiency of the manual operation and further reduce the possibility of an input error.

  A serial number corresponding to the tablet loading sequence is displayed on the upper surface of the tablet container 22 adjacent to the individual tablet container 21 together with the package number display units 101 and 102 or in place of the package number display units 101 and 102. May be.

  Referring to FIG. 1 and FIGS. 8A to 8C, two sensors 27 and 28 for detecting opening and closing of the sealing cover 25 are provided. The sensors 27 and 28 are arranged at the base end of the sealing cover 25 and rotate around the pin mechanisms 100A and 100B together with the sealing cover 25, and Hall elements that detect the magnetism of the magnetic bodies 27a and 28a. A fixed sensor main body 27b, 28b made of the like is provided. The magnetic bodies 27a and 28a included in the two sensors 27 and 28 are arranged at different angular positions in the pin shafts of the pin mechanisms 100A and 100B. On the other hand, the sensor bodies 27b and 28b of the two sensors 27 and 28 are opposed to the corresponding magnetic bodies 27a and 28b, and are disposed at the same angular position with respect to the pin axes of the pin mechanisms 100A and 100B. As will be described in detail later, by providing the two sensors 27 and 28, it is possible to detect whether the sealing cover 25 is accurately set to the closed position or the open position, and at least the sensors 27 and 28 are provided. When a failure occurs on one side, it is possible to prevent erroneous determination of whether the position is the closed position or the open position.

  8C, when the sealing cover 25 is in the closed position as shown in FIG. 8C, the magnetic body 27a and the sensor main body 27b are closest to each other and turned on, and the sealing cover 25 is turned on as shown in FIG. 8B. When in the open position, the magnetic body 27a and the sensor body 27b are separated from each other and are turned off. On the other hand, when the sealing cover 25 is in the open position as shown in FIG. 8B, the other sensor 28 is in the on state with the magnetic body 28a and the sensor body 28b being closest to each other, as shown in FIG. 8C. When the cover 25 is in the closed position, the magnetic body 28a and the sensor body 28b are separated from each other and are turned off. The configuration of the sensors 27 and 28 is not limited to this example. One sensor is turned on when the sealing cover 25 is in the closed position and turned off when the sealing cover 25 is in the opened position, and the other sensor is in the closed position when the sealing cover is in the closed position. If it is in the off state and it is in the open position, it may be in the on state.

  Referring to FIGS. 8A and 8C, the protective cover 26 is rotated around the pin mechanisms 100A and 100B when the sealing cover 25 is in the closed position, so that the open position (FIGS. 8B and 8C) and the closed position ( FIG. 8A) can be set. When the protective cover 26 is in the closed position, the upper end openings 21 a of all the tablet storage bowls 21 are covered with the protective cover 26. Therefore, when the tablet supply unit 2 is not used, it is possible to reliably prevent the entry of dust and the like into the tablet container 21 by setting the protective cover 26 in the closed position.

  Referring to FIGS. 1, 2, 9A, and 9B, the inner surface of the protective cover 26 is hidden behind the sealing cover 25 when the sealing cover 25 is in the open position (FIG. 9A). In the closed position (FIG. 9B), a display 32 indicating that all four rows of tablet storage baskets 21 are used is provided at a position that is exposed and visible. Accordingly, the operator can easily visually check whether the tablet container 21 of the tablet supply unit 2 is in a state corresponding to “minute 3” or “minute 2” or “minute 4”. it can.

  Referring to FIGS. 5A to 5C and FIG. 10, the tablet dispensing unit 23 of the tablet supply unit 2 is superposed on the upper shutter plate 34 disposed below the tablet storage unit 22 and below the upper shutter plate 34. The lower shutter plate 35 disposed at the bottom, the movable dispensing member 36 disposed below the lower shutter plate 35, and the fixed plate 37 disposed below the dispensing member 36.

  The upper and lower shutter plates 34 and 35 are movable in the row direction of the arrangement of the tablet storage baskets 21 while maintaining a state where they are overlapped with each other. The upper and lower shutter plates 34 and 35 are partitioned by a first partition 38 that extends in the column direction of the tablet container 21 and a second partition 39 that extends in the row direction of the tablet container 21. In addition, a total of 28 tablet passage holes 41 are formed in 4 columns and 7 rows corresponding to the tablet storage bowls 21 respectively. 5A to 5C of the upper and lower shutter plates 34, 35 are provided with locking portions 34a, 35a bent downward. Further, the upper shutter plate 34 is connected to the tablet housing portion 22 by a spring (not shown) and is elastically biased rightward in FIGS. 5A to 5C. Furthermore, the lower shutter plate 35 is connected to the upper shutter plate 34 by a spring (not shown), and is elastically biased rightward in FIGS. 5A to 5C. In an initial state where no external force is applied to the upper and lower shutter plates 34 and 35, the upper and lower shutter plates 34 and 35 are in the positions shown in FIG. 5A.

  The dispensing member 36 can be reciprocated in the row direction of the arrangement of the tablet container 21 by a driving device including a pinion rack mechanism and a motor. The dispensing member 36 is provided with a total of 28 tablet dispensing baskets 42 in 4 columns and 7 rows corresponding to the tablet housing baskets 21 of the tablet housing unit 22. The tablet dispensing basket 42 is open at both upper and lower ends. A bottom plate 43 that can be opened and closed is disposed in the opening on the lower end side of each tablet dispensing basket 42. One end of the bottom plate 43 is supported by a pin 44 so as to be swingable with respect to the payout member 36, and an opening weight 45 is built in the other end side.

  The bottom plate 43 of the tablet dispensing basket 42 is placed on the upper surface of the fixed plate 37, whereby the bottom plate 43 is held in the closed position. 5A to FIG. 5C and FIG. 10 of the fixed plate 37, the same number of steps 37a to 37d as the number of rows of the tablet containing basket 21 and the tablet dispensing basket 42 (four in this embodiment) are provided. Is provided. The steps between the adjacent steps 37a to 37d correspond to a value obtained by dividing the formation pitch in the row direction of the tablet storage basket 21 and the tablet discharge basket 42 by the number of columns of the tablet discharge basket 21 and the tablet discharge basket 42.

  Next, the operation of the tablet supply unit 2 will be described with reference to the flowchart of FIG. First, in step S1, the tablet button 9a (hereinafter, refer to FIG. 3 for buttons, LEDs, etc.) of the control panel 9 is selected, and in step S2, the LED corresponding to the tablet button 9a is turned on. Next, either “minute 3” or “minute 4” is selected in step S3. Specifically, when “minute 3” is selected, the blocking cover 25 is manually set to the closed position (FIGS. 8C and 9B) in step S4, and four rows of tablet storage baskets 21 are set in step S5. The LED 9b indicating use is turned off. When “minute 4” is selected, the blocking cover 25 is manually set to the open position (FIGS. 8B and 9A) in step S6, and the LED 9b is lit in step S6.

  Subsequently, the number of packages is set in step S8. If the number of packages set in step S9 is 21 or less, the partition plate 52 of the V 枡 51 described later is moved to a position corresponding to the number of packages to be set. The position of the partition plate 52 is detected by a sensor and output to the controller 11 of the tablet supply unit 2. The designated number is displayed on the number display part 9c of the control panel 9 in step S21. On the other hand, if the number of packages set in step S9 is 21 packages or more, the number of packages of the partition plate 52 of the V 枡 51 is set to the maximum value of 21 packages, and the package number display portion 9c of the control panel 9 is set in step S13. “21” is displayed as the number of packages. Each time the tablet button 9a of the control panel 9 is pressed in step S14, the number of packages from “22” to “28” which is the maximum number of packages of the tablet supply unit 2 is sequentially displayed in the package number display section 9c.

  Next, in step S <b> 15, the tablets are inserted from the upper end opening 21 a by manual operation and are stored in the individual tablet storage baskets 21. At this time, the tablets are sequentially inserted from the tablet storage basket 21 in the frontmost (near side) column of the rightmost row in the column direction to the rear side (back side).

  When the start button 9d of the control panel 9 is selected in step S16 after the manual operation is completed, the tablet dispensing unit 23 is operated in step S17, and one tablet is supplied from the tablet storage unit 22 through a conveyance path (not shown). It is sent to the hopper 67 of the packaging unit 4 in increments, and the packaging process is executed in the packaging unit 4.

  When the controller 11 detects that the sealing cover 25 is in an unstable state when the start button 9d is selected in step S16, the controller 11 outputs an error sound and prohibits the start of the operation of the tablet dispensing unit 23. The tablet is not supplied to the packaging unit 4. Specifically, if one sensor 27 is on and the other sensor 28 is off, the controller 11 determines that the sealing cover 25 is correctly set to the closed position (FIG. 8C) and dispenses the tablet. The unit 23 is operated. Further, if one sensor 27 is in an off state and the other sensor 28 is in an on state, the controller 11 determines that the sealing cover 25 is correctly set to the open position (FIG. 8B) and moves the tablet dispensing unit 23 to the position. Make it work. However, if the two sensors 27 and 28 are both in the off state or both in the on state, the controller 11 is in an unstable state (FIG. 8D) where the sealing cover 25 is neither in the closed position nor in the open position. It is determined that a failure has occurred in at least one, and the start of the operation of the tablet dispensing unit 23 is prohibited. By prohibiting the start of the operation of the tablet dispensing unit 23 when the sealing cover 25 is in an unstable posture, tablets stored in the individual tablet storage baskets 21 are erroneously packaged by the packaging unit 4 in an inaccurate manner. Can be surely prevented.

  Hereinafter, the operation of the tablet dispensing unit 23 in the packaging process in step S17 will be described in detail. First, before the start button 9d is selected, that is, when it is not in operation, the tablet dispensing unit 23 is in the state shown in FIG. 5A. That is, the upper and lower shutter plates 34, 35 have the lower end openings 21 b of the individual tablet storage bowls 21 formed by the first partition portion 38 of the upper shutter plate 34 and the first partition portion 38 of the lower shutter plate 35. In the holding position to close.

  As shown in FIG. 5B, when the start button 9d is selected and the sealing cover 25 is accurately set to the closed position or the open position and the sensor 27 or 28 is not in trouble, as shown in FIG. Moves to the left (row direction) in the figure. One end of the payout member 36 is hooked on the engaging portion 35a of the lower shutter plate 35, and as a result, the lower shutter plate 35 also moves leftward together with the payout member 36. When the payout member 36 further moves leftward in the figure, one end of the payout member 36 is hooked on the lock portion 34a of the upper shutter plate 34 via the lock portion 35a of the lower shutter plate 35. As a result, the upper shutter plate 34 Also moves leftward together with the payout member 36.

  By moving the upper and lower shutter plates 34 and 35 together with the dispensing member 36, the tablet dispensing unit 23 is in the state shown in FIG. 5C. That is, the upper and lower shutter plates 34 and 35 are configured such that the first partition portion 38 of the upper shutter plate 34 is retracted to the lower surface side of the first partition wall 24a of the tablet housing portion 22 and the lower shutter plate 35 One partition 38 is retracted to the lower surface side of the first partition 38 of the upper shutter plate 34, and the tablet passage holes 41, 42 of the upper and lower shutter plates 34, 35 are opened at the lower ends of the individual tablet storage bowls 21. It becomes an open position which respectively opposes 21b. When the upper and lower shutter plates 34 and 35 are in the open position, the opening on the upper end side of the tablet dispensing basket 42 of the dispensing member 36 is opposed to the respective lower end opening 21b. Therefore, one tablet of the tablet stored in each tablet storage basket 21 is stored in the tablet discharge basket 42 of the discharge member 36 through the lower end opening 21 b and the tablet passage holes 41, 41.

  Next, when the dispensing member 36 moves to the right in the figure, the bottom plate 43 of the tablet dispensing basket 42 reaches the drop port 48 in front of the steps 37a to 37d in order from the one in the moving direction, and the support is lost from below. Open. As a result, the tablets in the individual tablet dispensing baskets 42 are sequentially supplied into the hopper 67. In the case of “minute 4”, the payout member 36 always moves to the right intermittently by an amount corresponding to the above-mentioned step, but in the case of “minute 3”, it corresponds to the uppermost row. Since no tablets are stored in the tablet dispensing basket 42, after the third, sixth, ninth, twelfth, fifteenth tablet dispensing basket 42 reaches the drop opening 48. In the next intermittent movement, the movement amount of the payout member 36 is set to twice the step.

  As described above, since the lower end opening 21b is closed by the first partition portion 38 of the two shutter plates, that is, the upper and lower shutter plates 34 and 35, the upper and lower shutter plates 34 and 35 are individually closed. The width of the first partition 38 can be set narrow. Therefore, the width of the first partition wall 24a of the tablet housing part 22 where the first partition part 38 retracts in the open position can be set narrow, and the tablet supply unit 2 can be downsized. By downsizing the tablet supply unit 2, the medicine packaging apparatus 1 as a whole can be downsized.

(Powder supply unit)
The powder supply unit 3 is manually supplied with powder, and the powder is automatically divided into one package and supplied to the packaging unit 4 sequentially.

  Referring to FIGS. 1 and 2, the powder supply unit 3 includes an elongated ridge (V ridge 51) having a generally V-shaped cross section opened on the upper surface of the housing 5. The bottom of the V collar 51 can be opened and closed. In addition, a plurality of divided containers (not shown) are disposed below the V collar 51. When the bottom is opened, the powder charged in the V tub 51 falls into the dividing container and is divided into a predetermined amount. The bottom of the split container can also be opened and closed. By sequentially opening the bottoms of the divided containers, the powder in each divided container falls to the hopper 67 and is supplied to the packaging unit 4 for each package. In addition, a movable partition plate 52 for adjusting the number of divided powders is arranged in the V collar 51.

  The configuration of the powder supply unit 3 is not particularly limited as long as powder can be supplied to the packaging unit 4 one by one. For example, the powder supply unit 3 may supply powder that has been put into the hopper to the outer peripheral annular groove of the distribution tray, and sequentially supply the powder that has been scraped from the outer peripheral annular groove one by one by the scraping device to the packaging unit 4. Good.

(Packaging unit)
Hereinafter, the packaging unit 4 will be described with reference to FIGS. The packaging unit 4 includes a sheet supply unit 63, a deployment guide 65, a hopper 67, a heat seal unit 68, and a printing unit 69 on a holding frame 71. The sheet supply unit 63 unwinds and supplies the packaging sheet 61 from a roll 62 around which a long and narrow packaging sheet 61 folded in advance along the longitudinal direction is wound. The unfolding guide 65 unfolds and opens the bi-fold packaging sheet 61 supplied by the sheet supply unit 63. The hopper 67 has a loading opening 67b into which a drug is loaded from the tablet supply unit 2 and the powder supply unit 3 at the upper end, and functions as an inlet for introducing the drug into the opening of the folded folded packaging sheet 61. At the bottom. The heat seal part 68 seals the packaging sheet 61 so as to confine the introduced medicine, thereby creating a continuous medicine package. The continuous medicine package created by the heat seal unit 68 is cut by the cutter mechanism 201 schematically shown only in FIGS. 32 and 33 and separated for each prescription. The printing unit 69 is disposed between the sheet supply unit 63 and the deployment guide 65 in the path of the packaging sheet 61, and prints information such as a patient name, a drug name, and usage on the packaging sheet 61. As described above, the operation of the packaging unit 13 is controlled by the controller 13.

  Referring to FIGS. 12 to 16, the packaging unit 4 is provided on a holding frame 71 disposed in the accommodation chamber 7 of the housing 6. The holding frame 71 includes a front-side holding part 71a that spreads out on the front side of the housing 6, a side-side holding part 71b that extends from the right side to the back side as viewed from the front side of the front-side holding part 71a, and a front-side holding part 71a. A hinge mechanism 72 (see also FIG. 17 and FIG. 18) for rotatably connecting the left side end side to the housing 6 when viewed from the front side is provided. With this configuration, the packaging unit 4 can be accommodated in the housing 6 in a compact manner, and good workability can be ensured as will be described in detail later. There is a base plate (not shown) at a position directly above the upper end (see FIG. 14) of the holding frame 71, and the tablet supply unit 2 and the powder supply unit 3 are arranged on the base plate. Thus, the packaging unit 4 is accommodated compactly in the housing 6 in which the vertical space is limited by being provided on the holding frame 71.

  A roll 62 of the packaging sheet 61 is disposed at a lower portion of the side surface side holding portion 71 b of the holding frame 71. Further, two guide rollers 73 a and 73 b constituting a part of the sheet supply unit 63 are provided on the side surface side holding unit 71 b of the holding frame 71. The rotation centers of the roll 62 and the guide rollers 73a and 73b extend in a direction substantially orthogonal to the side surface side holding portion 71b (a direction in which the front side holding portion 71a spreads). Further, a printing unit 69 is disposed above the guide rollers 73 a and 73 b of the side surface side holding unit 71 b of the holding frame 71. The packaging sheet 61 is unwound from the roll 62 to the back side, is folded back to the front side in the horizontal direction by one guide roller 73a, is further turned upward by the other guide roller 73b, and is guided to the printing unit 69. . You may provide the hook-shaped part for preventing the meandering and dropping-off of the conveyance sheet 61 at the front-end | tip of guide roller 73a, 73b.

  The printing unit 69 includes a replaceable ink cartridge 76 having a winding roller and a winding roller for the ink ribbon 75 for thermal transfer, a biasing roller 77 for applying tension to the ink ribbon 75, a thermal transfer head 78, and a thermal transfer. A backup roller 79 for bringing the packaging sheet 61 into close contact with the ink ribbon 75 at the head 78 is provided.

  A fixed guide rod 81 for curving the conveyance direction of the packaging sheet 61 that has passed through the printing unit 69 just before the unfolding guide 65 at a position above the front holding unit 71a of the holding frame 71 and on the right end side when viewed from the front. (A curved guide constituting a part of the sheet supply unit 63) is arranged (see particularly FIG. 12). Specifically, the guide rod 81 curves the conveyance direction of the packaging sheet 61 heading from the rear to the front along the side-side holding part 71b to the front side of the front-side holding part 71a, and the front side of the front-side holding part 71a The packaging sheet 61 is guided obliquely downward as viewed from the side. The guide rod 81 extends from the front side holding portion 71a in a direction in which the front side holding portion 71a spreads and obliquely downward. As shown most clearly in FIG. 12, the direction in which the side edge of the guide rod 81 on the downstream side in the conveying direction of the packaging sheet 61 extends coincides with the direction in which the main ridgeline 94 of the development guide 65 described later extends. .

  In the front-side holding portion 71a of the holding frame 71, a deployment guide 65 is disposed obliquely below the guide rod 81 (downstream in the conveyance direction of the packaging sheet 61) as viewed from the front. The deployment guide 65 will be described in detail later. A hopper 67 is held by the front-side holding portion 71a of the holding frame 71, and the nozzle portion 67a at the lower end of the hopper 67 is located obliquely to the left of the unfolding guide 65 when viewed from the front. Further, a heat seal portion 68 is disposed on the front holding portion 71a of the holding frame 71 at a position obliquely below the nozzle portion 67a of the hopper 67 when viewed from the front.

  Referring to FIGS. 12 and 15, the heat seal portion 68 includes a pair of feed rollers 82 a and 82 b that are rotationally driven intermittently by a drive mechanism (not shown) including a motor, a linear gear, an intermittent gear, and the like. The packaging sheet 61 is sandwiched between the feed rollers 82a and 82b, and is conveyed by intermittent rotation of the feed rollers 82a and 82b. Further, a pair of heater rollers 83a and 83b are provided on the upstream side in the feed direction of the packaging sheet 61 with respect to the feed rollers 82a and 82b. Each of the heater rollers 83a and 83b includes a disk-shaped feed heat seal member 84 and a thin rectangular plate-shaped vertical heat seal member 86 integrally formed with a roller member 85 having the same diameter as the feed heat seal member 84 at the lower end. It has. The feed heat seal members 84 and 84 are rotationally driven by a drive mechanism (not shown) including a motor common to the feed rollers 82a and 82b. The vertical heat seal members 86 and 86 are rotationally driven by a drive mechanism different from the feed heat seal portions 84 and 84. A longitudinal seal (lateral seal) is formed on the side edge of the packaging sheet 61 between the feed heat seal members 84, 84 of both heater rollers 83a, 83b. A seal (vertical seal) across the packaging sheet 61 is formed by the vertical heat seal members 86, 86 of the heater rollers 83a, 83b.

  The deployment guide 65 will be described in detail with reference to FIGS. The unfolding guide 65 has a guide body 91 having a function of unfolding the folded folded packaging sheet 61 and forming an opening for inserting the nozzle portion 67a of the hopper 67, and holds the guide body 91 via the bracket 92. An elongated plate-shaped attachment portion 93 for fixing to the front side holding portion 71a of the frame 71 is provided. The deployment guide 65 is fixed to the bracket 92 with screws by screws (not shown) inserted through the through holes 93a and 93b of the attachment portion 93, respectively.

  The guide main body 91 of the unfolding guide 65 is convex when viewed from the main ridgeline 94 extending along the fold of the packaging sheet 61 and the conveying direction of the packaging sheet 61 spreading from the main ridgeline 94 (see arrow A in FIGS. 23 and 24). A pair of unfolding guide surfaces 90a and 90b that are symmetrical with respect to the main ridgeline 94, and the main ridgeline 94 from the upstream end in the transport direction A of the packaging sheet 61 of the main ridgeline 94. A pair of top surfaces 96 a and 96 b that are convex curved surfaces as viewed from the upstream side in the conveyance direction A of the packaging sheet 61 extending from the auxiliary ridge line 95 and that extend from the auxiliary ridge line 95 and are symmetric with respect to the auxiliary ridge line 95. , And rear end edges 97a, 97b extending from the downstream end of the main ridgeline 94 in the conveying direction of the packaging sheet 61. When viewed from the upstream side in the conveyance direction A of the packaging sheet 61, the guide body 91 narrows toward the downstream side in the conveyance direction A of the packaging sheet 61 (expands toward the upstream side in the conveyance direction A of the packaging sheet 61). A curved surface. On the other hand, when viewed from the downstream side in the conveying direction A of the packaging sheet 61, the guide main body 91 has a concave shape or a concave shape, and the concave portion is closed by a closing plate 98 schematically shown only in FIG. Does not stay in this dent.

  When viewed from the conveyance direction A of the packaging sheet 61, the outer shape of the unfolding guide surfaces 90a and 90b is a convex curve, and the distance between the pair of unfolding guide surfaces 90a and 90b increases as the distance from the main ridge line 94 increases. (See FIG. 21). Further, when viewed from a direction (see arrow B in FIGS. 23 and 24) perpendicular to the conveyance direction A of the packaging sheet and directly facing the main ridgeline 94, the deployment guide surfaces 90a and 90b have a linear outer shape. Thus, the interval between the development guide surfaces 90a and 90b is narrowed from the upstream side to the downstream side in the conveyance direction A of the packaging sheet 61 (see FIG. 22).

  The unfolding guide 65 includes a pair of unfolding guide surfaces 90 a and 90 b made of such a convex curved surface, and a direction in which the side edge of the guide rod 81 on the downstream side in the conveying direction of the packaging sheet 61 extends, and the main ridge line of the unfolding guide 65. By matching the extending direction of 94, the folded folded packaging sheet 61 is guided by a curved surface so that it is gently deformed or expanded, and tension is applied evenly to each of the folded folded sheet 61. An opening can be formed. Therefore, even if the printing unit 69 is disposed close to the development guide 65 and the heat seal unit 68, it is possible to reliably prevent wrinkles from being generated on the packaging sheet 61 by the heat seal unit 68. In other words, the distance from the printing unit 69 to the heat seal unit 68 can be shortened without causing wrinkles in the packaging sheet 61 due to the shape of the deployment guide 65. As a result, when the medicine packaging apparatus 1 is first started up or when the roll 62 is replaced, the wasteful packaging sheet 61 (packaging sheet from the printing section to the heat seal section) that is used only for routing and not used for packaging the medicine. ) Can be shortened to a minimum, and running costs can be reduced. Further, by reducing the distance from the printing unit 69 to the heat seal unit 68, the apparatus can be reduced in size.

  As shown most clearly in FIGS. 23 and 24, the rear end edges 97 a and 97 b of the above-described deployment guide 65 have a first angle that is acute with respect to the main ridgeline 94 at the connection position with the main ridgeline 94. An angle θ1 (for example, 50 °) is formed, and a second angle θ2 (for example, 60 °) larger than the first angle θ1 is formed with respect to the main ridgeline at a portion other than the connection position with the main ridgeline 94.

  With the shape of the rear end edges 97a and 97b of the development guide surfaces 90a and 90b, it is possible to achieve both prevention of drug retention and reliable prevention of wrinkling of the packaging sheet 61. By setting the first angle θ1 formed between the rear end edges 97a and 97b and the main ridgeline 94 as small as possible, the development guide surfaces 90a and 90b on the downstream side in the transport direction A of the packaging sheet 61. It can prevent that the chemical | medical agent (especially powdered medicine) introduce | transduced from the nozzle part 67a of the hopper 67 stays in the edge part of this. On the other hand, since the angle between the rear end edges 97a and 97b and the main ridge line 94 is a second angle θ2 that is larger than the first angle θ1, the area of the development guide surfaces 90a and 90b is the packaging sheet 61. Can be set wide enough to prevent wrinkles.

  The upstream portion of the unfolding guide 65 in the conveyance direction A of the packaging sheet 61 is a sub-ridge line 95 that extends continuously from the main ridge line 94 and a convex curved surface that extends symmetrically with respect to the sub-ridge line 95 as described above. It is constituted by a certain pair of top surfaces 96a and 96b. The top surfaces 96a and 96b are connected to the deployment guide surfaces 90a and 90b, respectively. The connection portions between the deployment guide surfaces 90a and 90b and the top surfaces 96a and 96b include the deployment guide surfaces 90a and 90b and the top surfaces 96a and 96b. Shoulder portions 99a and 99b that are continuous curved surfaces are formed. Even if the medicine (especially powder) introduced from the nozzle portion 67a of the hopper 67 is lowered to the top surfaces 96a and 96b of the deployment guide by blowing up or the like, the top surfaces 96a and 96b are curved surfaces. It falls into the packaging sheet 61 without accumulating in 96b.

  The roll 62 of the packaging sheet 61, the guide rollers 73a and 73b, and the printing unit 69 are disposed on the side surface side holding portion 71b of the holding frame 71, while the backup roller 79, the guide rod 81, the deployment guide 65, the front side holding portion 71a, A hopper 67 and a heat seal portion 68 are arranged. Therefore, as shown in FIG. 17, the roll 62 of the packaging sheet 61, the guide rollers 73a and 73b, the printing unit 69, the backup roller 79, the guide rod 81, the unfolding guide 65, the hopper 67, and the heat seal unit 68 are arranged in a compact manner. Thus, the space in the housing chamber 7 of the housing 6 can be used. In other words, the medicine packaging device 1 can be downsized. On the other hand, as shown in FIG. 18, when the holding frame 71 is rotated by the hinge mechanism 72, almost the entire packaging unit 4 is removed from the housing 6, and the roll 62 and the printing unit 69 of the packaging sheet 61 are moved. Since it can be easily accessed and visually recognized from the outside by moving it to the front side of the housing 6, workability of various operations such as maintenance of the printing unit 69 including replacement of the roll 62 and replacement of the ink ribbon cartridge 76 is easy. is there.

(Second Embodiment)
Next, a second embodiment of the present invention will be described with reference to FIGS. In the second embodiment, only the packaging unit 4 in the medicine packaging apparatus 1 is different from the first embodiment, and the configurations and operations of the tablet supply unit 2, the powder supply unit 3, and the medicine discharge unit 5 are the same as those in the first embodiment. It is the same.

  The packaging unit 4 in the present embodiment is a packaging sheet in which tablets supplied from the tablet supply unit 2 to the hopper 67 and powders supplied from the powder supply unit 3 to the hopper 67 are adhered to the wall surface in the hopper 67. A mechanism for preventing the hopper 67 from remaining without being supplied to the hopper 67 is provided. Specifically, the packaging unit 4 in the present embodiment includes a hopper side vibration applying mechanism 202 that applies vibration to the hopper 67 and a deployment guide side vibration applying mechanism 203 that applies vibration to the deployment guide 65.

  Referring to FIGS. 25 and 28, the hopper 67 in the present embodiment includes a generally rectangular charging opening 67b in plan view, and four inner inclined wall surfaces 67c extending obliquely downward from the charging opening 67b toward the nozzle portion 67a. , 67d, 67e, 67f. A space surrounded by these inner inclined wall surfaces 67c to 67f is partitioned by a partition plate portion 67g. In FIG. 28, the tablet is supplied from the tablet supply unit 2 to the space on the left side of the partition plate portion 67g, and the powder is supplied from the powder supply unit 3 to the space on the right side. Of the four inner inclined wall surfaces 67c to 67f, the right side of the partition plate portion 67g in FIG. 28 is used to ensure a large area in plan view of the portion of the charging opening 67b to which the powder supply unit 3 supplies powder. The inner inclined wall surface 67c has a smaller inclination angle than the remaining three inner inclined wall surfaces 67d to 67f. Specifically, the inclination angle of the inner inclined wall surfaces 67d to 67f is set to about 75 to 85 °, while the inclination angle of the inner inclined wall surface 67c is set to about 35 to 40 °. The inclination angle of the inner inclined surface 67e is set to 64 °.

  Further, the hopper 67 in the present embodiment includes a held portion 67h that is held by a hopper holding portion 206 of a hopper side vibration applying mechanism 202 described later. The held portion 67h is provided in the vicinity of the closing opening 67b outside the inner inclined wall surface 67f. The held portion 67h is in the form of an elongated block having a recess 67i formed on the lower end surface, a held surface 67j inclined on one end side (left side in FIG. 28) is formed, and a projection 67k is formed on the other end side. Yes. In the vicinity of the closing opening 67b on the outer side of the inner inclined wall surface 67d facing the held portion 67h, a knob portion 67m for the operator to hold the hopper 67 is provided.

  Referring to FIGS. 25 to 28, the hopper side vibration applying mechanism 202 includes a resin holding structure 205 fixed to the holding frame 71 via a bracket 204. The holding structure 205 includes an elongated hopper holding portion 206 extending in the horizontal direction. The hopper 67 is held by the hopper holding portion 206 in such a posture that the longitudinal direction of the charging opening 67b (the direction in which the upper edge of the inner inclined surfaces 67d and 67f extends) coincides with the longitudinal direction of the hopper holding portion 206 in plan view. In order to detachably hold the held portion 67h of the hopper 67, the hopper holding portion 206 includes an inverted L-shaped hook portion 206a that protrudes upward slightly from the right end in FIG. Is provided with a locking mechanism 206b. The lock mechanism 206b includes an operation lever 206c that can be rotated around an axis in the horizontal direction (see arrow D). Further, the lock mechanism 206b is disposed closer to the center of the hopper holding portion 206a than the operation lever 206c, and similarly includes a lock lever 206d that can be rotated around a horizontal axis (see arrow E).

  A held portion 67f of the hopper 67 is detachably fixed on the hopper holding portion 206. As shown in FIG. 28, in a state where the hopper 67 is fixed to the hopper holding portion 206, the protrusion 67k of the held portion 67f fits below the hook portion 206a of the hopper holding portion 206, and the held surface 67j is locked. It is pressed down by the holding surface 206g of the lever 206d. The lock lever 206d is held in a non-rotatable state by the fixed portion 206e opposite to the holding surface 206g being locked to the fixing portion 206f of the operation lever 206c. When the knob 206h of the operation lever 206c is operated and rotated counterclockwise in FIG. 28, the fixing portion 206f of the operation lever 206c is detached from the fixed portion 206e of the lock lever 206d. As a result, the lock lever 206d is rotatable and the pressing of the held surface 67j by the holding surface 206g is released, so that the held portion 67h of the hopper 67 can be attached to and detached from the hopper holding portion 206. The manner in which the hopper 67 is detachably attached to the hopper holding portion 206 is not limited to that of the present embodiment as long as the hopper 67 can be fixed to the hopper holding portion 206 to some extent. For example, the hopper 67 may be detachably attached to the hopper holding portion 206 by fixing with a magnet, screwing, or the like.

  In FIG. 28 of the hopper holder 206, a vibration motor holder 207 is provided below the right end. The vibration motor holding part 207 includes a cylindrical main body 207a held by the vibration motor 208 and a connecting part 207b for connecting the main body 207a and the lower surface of the hopper holding part 206. The vibration motor 208 is held in a state of being suspended on the lower surface side of one end of the hopper holding portion 206.

  The type of the vibration motor 208 is not particularly limited as long as at least operation start and stop can be electrically controlled. The vibration motor 208 in this embodiment uses a type in which a weight is fixed to a rotating shaft of a DC motor and is built in a casing. A vibration motor 211 described later also uses the same type as the vibration motor 208.

  The holding structure 205 includes two leaf spring portions 209a and 209b whose upper end side is coupled to the hopper holding portion 206 and whose lower end side is fixed to the bracket by screws. In a plan view, the leaf springs 209a and 209b extend from the hopper holding portion 206 directly below (vertically downward). In a side view, the leaf spring portions 209a and 209b extend in parallel downward from the hopper holding portion 206 so as to move away from the vibration motor holding portion 207 (vibration motor 208) toward the lower end side. 206 are arranged at intervals in the longitudinal direction. The inclination angle θ with respect to the horizontal direction of the leaf spring portions 209a and 209b is set to about 80 °, for example. The leaf spring portions 209a and 209b bend in a cantilever manner in which the lower end side is a fixed end and the upper end side is a free end. .

  The vibration generated by the operation of the vibration motor 208 is transmitted to the hopper 67 through the holding structure 205. Due to this vibration, the tablets supplied from the tablet supply unit 2 and the powder supplied from the powder supply unit 3 do not adhere to the inner inclined wall surfaces 67c to 67f of the hopper 67, and quickly pass from the charging opening 67b to the nozzle portion 67a. And is introduced into the opening of the half-folded packaging sheet 61 developed by the deployment guide 65. Therefore, contamination can be eliminated by effectively preventing the drug (particularly powder) from adhering to and remaining on the hopper 67 in this way. In addition, compared to the sound generated when the hopper is hit with a solenoid or the like, the sound generated by applying the vibration has a low volume, does not give the operator a sense of discomfort, and the operator does not misidentify the occurrence of the failure.

  As shown by an arrow H in FIG. 28, the holding structure 205 in the present embodiment having the above-described structure is in a plane including a moving direction F and a gravitational direction G in which the powdered medicine moves on the inner inclined surface 67c having the gentlest inclination. In FIG. 28, the vibration generated by the vibration motor 208 is transmitted to the hopper 67 so that the hopper 67 vibrates along an elliptical track that is further away from the inner inclined surface 67 c toward the upper end side. The major axis M of the elliptical orbit H of vibration of the hopper 67 is orthogonal to the leaf spring portions 209a and 209b (inclination angle θ), and the movement direction F in which the powdered powder moves by its own weight on the inner inclined surface 67c. The formed angle θH is less than 90 degrees, but is a relatively large angle (about 45 degrees or more and less than 90 degrees). By giving vibration of the elliptical orbit, the powder on the gently inclined inner inclined surface 67c can be efficiently moved from the injection opening 67b to the nozzle portion 67a, and the residue due to adhesion is surely prevented. it can. Further, since the vibration motor 208 is located near the upper end of the inner inclined surface 67c, the vibration generated by the vibration motor 208 is efficiently transmitted to the inner inclined surface 67c, and the movement of the medicine on the inner inclined surface 67c is promoted. To do.

  29 and 30, the deployment guide side vibration applying mechanism 203 includes a vibration motor (second vibration source) 211 built in the deployment guide 65. A plurality of radially extending ribs 212 are provided inside the deployment guide 65, and the vibration motor 211 is fixed to the deployment guide 65 by these ribs 212. Accordingly, the vibration generated by the vibration motor 65 is directly transmitted to the deployment guide 65. By applying vibration not only to the hopper 67 but also to the deployment guide 65 by the deployment guide side vibration application mechanism 203, the movement or flow of the medicine (particularly powder) in the folded packaging sheet 61 becomes smooth. It is possible to more reliably prevent the drug from adhering to the hopper 67 and remaining.

  Hereinafter, control of the hopper side vibration applying mechanism 202 and the unfolding guide side vibration applying mechanism 203 by the controller 11 will be described. In the present embodiment, the hopper side vibration applying mechanism 202 and the unfolding guide obtaining side vibration applying mechanism 203 operate in synchronization, and the hopper side vibration applying mechanism 202 and the unfolding guide side vibration applying mechanism 203 always operate simultaneously and stop simultaneously. However, the hopper side vibration applying mechanism 202 and the unfolding guide obtaining side vibration applying mechanism 203 may operate independently of each other. In the following description, the hopper side vibration applying mechanism 202 and the unfolding guide obtaining side vibration applying mechanism 203 are collectively referred to as vibration applying mechanisms 202 and 203 unless particularly distinguished.

  First, the vibration applying mechanisms 202 and 203 are in a state in which the tips of the vertical heat seal portions 86 and 86 (see, for example, FIGS. 12 and 15) of the heater rollers 83 a and 83 b face each other and sandwich the packaging sheet 61, that is, the vertical heat seal portion 86. , 86 start operation after a predetermined time after reaching the position for forming the vertical seal. Further, the operation continuation time of the vibration applying mechanisms 202 and 203 is set according to the packaging speed. The feeding speed of the packaging sheet 61 by the feeding rollers 82a and 82b (see, for example, FIGS. 12 and 15) is faster in the tablet packaging than in the powder packaging. Therefore, the vertical heat seal portions 86 and 86 form a vertical seal. The time from when the position is reached to when the vibration applying mechanisms 202 and 203 start to operate is set shorter in the tablet packaging than in the powder packaging. Further, for both powder packaging and tablet packaging, the time until the vibration applying mechanisms 202 and 203 start operating is set longer as the feeding speed of the packaging sheet 61 is slower. In addition, when both powder and a tablet are included in one prescription (tablet simultaneous packaging), the operation timing and operation duration of the vibration applying mechanisms 202 and 203 are set in the same manner as during powder packaging.

  When a medicine package that divides a tablet and a medicine package that scatters a powder are mixed in one prescription (mixed sachet), the controller 11 uses the same timing as during the powder sachet for a medicine package that divides the powder. The vibration applying mechanisms 202 and 203 are operated with the operation duration time, and the vibration applying mechanisms 202 and 203 are operated with the same timing and the operation duration time as in the tablet packaging for the medicine package for packaging the tablets. In order to reliably prevent the powder remaining on the hopper 67 from being mixed into the medicine package for packaging the tablet, the controller 11 once forms the medicine package for packaging the powder in the mixed packaging. During the preparation of the medicine package for packaging the tablets, the vibration applying mechanisms 202 and 203 are not operated and are maintained in the stopped state. FIG. 31 schematically shows the operation of the vibration applying mechanisms 202 and 203 during the mixing and packaging. In this example, in 3 minutes, the tablet is taken in “morning” and “noon”, and the powder is taken in “evening”. Among the symbols displayed on the lower side of the medicine pack 215 schematically shown, “◯” indicates that the vibration applying mechanisms 202 and 203 are operated, and “×” indicates that the vibration applying mechanisms 202 and 203 are maintained in a stopped state. It shows that. The first and second medicine packages 215 are tablets, but no powder is packaged in the same formulation. Therefore, even if the first and second medicine packs 215 are tablets, the vibration applying mechanisms 202 and 203 are operated as in the case of powder medicine. The third medicine package 215 is a medicine bag that first divides the powder within the same prescription, and the vibration applying mechanisms 202 and 203 are operated while the third medicine package 215 is formed. The 6th package that keeps the vibration application mechanisms 202 and 203 in a stopped state when the 4th, 5th, 7th, and 8th packet sachets 215 that sachet the tablets after the 3rd sachet are packaged. During the formation of the ninth medicine bag 215, the vibration applying mechanisms 202 and 203 operate.

  Referring to FIGS. 32 and 33, an empty medicine package (loss bag 216) that does not wrap a medicine is provided in order to separate successive medicine packages for each prescription, and the loss bag 216 is cut by the cutter mechanism 201. If a drug (particularly powder) is mixed in the loss bag 216, the drug mixed when the cutter mechanism 201 cuts out flows into the apparatus and causes contamination. Therefore, when the controller 11 determines that the loss bag 216 is being created based on the input prescription information, the controller 11 maintains the vibration applying mechanisms 202 and 203 in a stopped state. In the example of FIG. 32, the loss bag 216 of the first package and the loss bag 216 of the second package in the example of FIG. 33 are objects to be cut by the cutter mechanism 201. Therefore, the vibration applying mechanism 202, 203 is maintained in a stopped state.

(Third embodiment)
Next, a third embodiment of the present invention will be described with reference to FIGS. This third embodiment differs from the second embodiment in the structure of the held portion 67h of the hopper 67 and the hopper side vibration applying mechanism 202.

  Referring to FIG. 39, the held portion 67 of the hopper 67 according to the present embodiment is configured such that the held portion 67h is a block-shaped first and second portion 67n provided in the vicinity of the closing opening 67b outside the inner inclined wall surface 67f. , 67p. An inclined held surface 67q is formed on one end side (left side in FIG. 39) of the first portion 67n, and a protrusion 67r is formed on the other end side. A protrusion 67s is also provided on one end side (right side in FIG. 39) of the second portion 67p.

  The holding structure 205 provided in the hopper holding mechanism 202 of the present embodiment includes a base 307 that is separate from the hopper holding unit 206. The hopper holding portion 206 and the base portion 307 are connected to each other by separate leaf springs 308a and 308b that are screwed at both upper and lower ends. In a plan view, the leaf springs 308a and 308b extend directly from the hopper holding portion 206 (vertically downward). In a side view, the leaf springs 308a and 308b extend in parallel downward from the hopper holding portion 206 so as to be closer to the vibration motor holding portion 207 (vibration motor 208) toward the lower end side. 206 are arranged at intervals in the longitudinal direction. The inclination angle θ of the leaf springs 308a and 308b with respect to the horizontal direction is set to about 80 °, for example. The leaf springs 308a and 308b are bent in a cantilever manner with the lower end side being a fixed end and the upper end side being a free end. When the upper ends of the leaf springs 308a and 308b are displaced due to this bending, the hopper holding portion 206 is displaced accordingly.

  As shown by an arrow H in FIG. 39, the holding structure 205 in the present embodiment having the above-described structure is in a plane including a moving direction F and a gravitational direction G in which the powdered medicine moves on the inner inclined surface 67c having the gentlest inclination. In FIG. 39, the vibration generated by the vibration motor 208 is transmitted to the hopper 67 so that the hopper 67 vibrates along an elliptical track that is further away from the inner inclined surface 67 c toward the upper end side. The major axis M of the elliptical orbit H of vibration of the hopper 67 is perpendicular to the leaf springs 308a and 308b (inclination angle θ), and is formed with the moving direction F in which the powdered drug moves by its own weight on the inner inclined surface 67c. The angle θH is an acute angle sufficiently smaller than 45 degrees (about 5 ° to 15 °). By giving vibration of the elliptical orbit, the powder on the gently inclined inner inclined surface 67c can be efficiently moved from the injection opening 67b to the nozzle portion 67a, and the residue due to adhesion is surely prevented. it can. Compared to the case where the angle θH is a relatively dull angle as in the second embodiment, the moving speed of the powder on the inner inclined surface 67c can be further increased by setting the angle θH to a sufficiently small acute angle. . Further, since the vibration motor 208 is located near the upper end of the inner inclined surface 67c, the vibration generated by the vibration motor 208 is efficiently transmitted to the inner inclined surface 67c, and the movement of the medicine on the inner inclined surface 67c is promoted. To do.

  The hopper holding portion 206 in the present embodiment includes reverse L-shaped hook portions 306a and 306b that protrude upward. Further, the hopper holding portion 206 includes a rotatable lever 306d that can be used as a lock mechanism 306c. As shown in FIG. 39, when the hopper 67 is fixed to the hopper holding portion 306, the protrusions 67r and 67s of the held portion 67 are fitted into the hook portions 306a and 306b on the lower side, and the held surface 67q is the lever 306d. It is pressed down by the holding surface 306e. When the lever 306d is rotated clockwise in FIG. 39, the holding surface 306e of the lever 306d is detached from the held surface 67q, and the hopper 67 can be attached to and detached from the hopper holding portion 206.

  Other configurations and operations of the third embodiment are the same as those of the second embodiment. In adopting the hopper side vibration applying mechanism 202 and the unfolding guide side vibration applying mechanism 203 of the second and third embodiments, the supply form of the packaging sheet 61 is not particularly limited. Specifically, the packaging sheet 61 may be held in a wound state on the roll 62 without being folded in two, and may be folded in two after being unwound from the roll 62. Although not shown in FIGS. 25 to 33, a deployment guide-side vibration applying mechanism is accommodated in the deployment guide 65, as in the second embodiment.

(Fourth embodiment)
A fourth embodiment of the present invention will be described with reference to FIGS. 40 to 44. In this 4th Embodiment, the structure of the expansion | deployment guide 65 with which the packaging unit 4 of the chemical | medical agent packaging apparatus 1 is provided differs from 1st to 3rd embodiment. In the fourth embodiment, three guide rollers b, 401b, 401c are provided instead of the guide rod 81, and the conveying direction of the packaging sheet 61 is set immediately before the unfolding guide 65 by these guide rollers 401a-401c. It is curved. Of the three guide rollers 401a to 401c, a small-diameter columnar protrusion 410 that protrudes upward is provided at the upper end of the guide roller 401a closest to the unfolding guide 65. The protrusion 410 has a function of preventing the packaging sheet 61 from meandering and dropping off. Since the conveyance direction of the packaging sheet 61 is curved obliquely downward at the guide roller 401a, the provision of the protrusions 410 can effectively prevent the packaging sheet 61 from meandering and dropping off. In addition, since the small-diameter cylindrical peripheral surface of the protrusion 410 contacts the packaging sheet 61, the contact resistance with respect to the packaging sheet 61 is extremely small.

  As shown most clearly in FIG. 42, in the present embodiment, of the pair of shoulder portions 99a and 99b provided in the deployment guide 65, the inside (front) of the curve in the conveyance direction of the packaging sheet 61 with respect to the main ridgeline 94. The shoulder 99b on the back side when the side holding part 71 is viewed from the front is the outer side of the curve with respect to the main ridgeline 94 (the front side when the front side holding part 71 is viewed from the front). It bulges about 2 to 4 mm (about 3 mm in this embodiment) with respect to the main ridgeline 94 than 99a. As the shoulder 99b bulges in this way, the rear-side deployment guide surface 90b and the top surface 96b connected to the shoulder 99b also bulge more than the front-side deployment guide surface 90a and the top surface 96b. . Further, the connection position 405b between the rear shoulder 99b and the deployment guide surface 90b is located closer to the rear edge 97a, 97b than the connection position 405a between the front shoulder 99a and the deployment guide surface 90a. However, the angle formed by the development guide surface 90b on the back side with respect to the main ridgeline 94 at the rear end edges 97a and 97b is substantially equal to the angle formed by the development guide surface 90a on the labor side with respect to the main ridgeline 94. In other words, the symmetry of the shape of the deployment guide 91 is ensured near the rear end of the main ridgeline 94.

  The conveyance direction of the folded folded packaging sheet 61 is curved by the guide rollers 401a to 401b. On the downstream side of the curved portion, the inner side of the curve (the back side when the front side holding portion 71 is viewed from the front side). Side) of the packaging sheet 61 (one of the two folds), the tension acting on the outer side of the curve (the front side when the front side holding part 71 is viewed from the front) of the packaging sheet 61 (of the two folds) It tends to be weaker than the tension acting on the other. Due to the tension imbalance between the inside and the outside, the packaging sheet 61 on the inside of the curve is likely to be loosened, and this looseness is a state in which both side edges (so-called “ears”) of the folded folded packaging sheet 61 are not aligned ( So-called “ear loss”). The contact resistance of the thermal transfer head 78 and the like of the printing unit 69 located upstream of the unfolding guide 91 and the guide rollers 401a to 401c also causes a tension imbalance between the inner packaging sheet 61 and the outer packaging sheet 61. There is a tendency to encourage.

  However, in the deployment guide 91 in the present embodiment, the back side shoulder 99b, the deployment guide surface 90b, and the top surface 90b bulge more than the front shoulder 99a, the deployment guide surface 90a, and the top surface 90a. Because of the shape, the tension acting on the packaging sheet 61 is balanced at the portion where the main ridgeline 94, both shoulders 99a, 99b, and both deployment guide surfaces 90a, 90b contact the packaging sheet 61. In particular, the tension acting on the packaging sheet 61 is balanced by contact of the shoulder portions 99a, 99b and the vicinity of the rear end of the main ridge line 94 with the packaging sheet 61. As a result, the tension is uniformly applied to both of the double-folded packaging sheets 61, and the packaging sheet 61 is in a state where both side edges of the double-fold are aligned (so-called “ears are aligned”) by the deployment guide 91. In the deployment, the occurrence of wrinkles can be prevented more reliably.

  Other configurations and operations of the fourth embodiment are the same as those of the third embodiment. Although not shown in FIGS. 40 to 44, a deployment guide-side vibration applying mechanism is accommodated in the deployment guide 65 as in the second embodiment.

DESCRIPTION OF SYMBOLS 1 Drug packaging device 2 Tablet supply unit 3 Powder supply unit 4 Packaging unit 5 Drug discharge part 6 Housing 7 Storage chamber 8 Cover 9 Control panel 9a Tablet button 9b LED
9c Packing display section 9d Start button 11, 12, 13 Controller 21 Tablet storage chamber 21a Tablet insertion opening 21b Tablet passage opening 22 Tablet storage section 23 Tablet dispensing section 24a, 24b Partition 25 Sealing cover 26 Protective cover 27, 28, 29, 30 Sensor 27a, 28a Magnetic body 27b, 28b Sensor main body 32 Display 34 Upper shutter plate 34a Locking portion 35 Lower shutter plate 35b Locking portion 36 Discharge member 37 Fixing plate 38, 39 Partition portion 41 Tablet passage hole 42 Tablet discharge chamber 43 Bottom plate 44 Pin 45 Weight 48 Drop port 51 V 枡 61 Packaging sheet 62 Roll 63 Sheet supply part 65 Deployment guide 67 Hopper 67a Nozzle part 67b Input opening 67c to 67f Inner inclined wall surface 67g Partition plate part 67h Held part 67i Recessed part 67j Held Surface 67k protrusion 7 m Knob 68 Heat seal 69 Print unit 71 Holding frame 71a Front side holding part 71b Side side holding part 72 Hinge mechanism 73a, 73b Guide roller 75 Ink ribbon 76 Ink cartridge 77 Energizing roller 78 Thermal transfer head 79 Backup roller 81 Guide rod 82a, 82b Feed roller 83a, 83b Heater roller 84 Feed heat seal member 85 Roller member 86 Vertical heat seal member 90a, 90b Deployment guide surface 91 Guide body 92 Bracket 93 Mounting portion 93a, 93b Through hole 94 Main ridge line 95 Sub ridge line 96a, 96b Top surface 97a, 97b Rear edge 98 Closure plate 99a, 99b Shoulder part 100A, 100B Pin mechanism 101, 102 Packet display part 201 Cutter mechanism 202 Hopper side vibration applying mechanism 203 Exhibition Guide side vibration applying mechanism 204 Bracket 205 Holding structure 206 Hopper holding portion 206a, 306a, 306b Hook portion 206b Lock mechanism 206c Operation lever 206d Lock lever 206e Fixed portion 206f Fixing portion 206g Holding surface 206h Knob portion 207 Vibration motor holding portion 207a Main body 207b connecting portion 208 vibration motor 209a, 209b leaf spring portion 211 vibration motor 212 rib 215 medicine package 216 loss bag 308a, 308b leaf spring

Claims (13)

  In a medicine packaging apparatus comprising a medicine introduction part for introducing a medicine from an opening of an elongated packaging sheet folded in two along the longitudinal direction, and a heat seal part for sealing the packaging sheet so as to confine the introduced medicine,
  An unfolding guide for unfolding the folded package sheet to form the opening;
  The medicine introduction part has an introduction opening into which medicine is introduced in the upper part, and a hopper having a nozzle part in the lower part that is inserted into the opening of the folded folded packaging sheet and introduces the medicine into the packaging sheet. When,
  A first vibration applying mechanism for applying vibration to the hopper;
  A second vibration applying mechanism for applying vibration to the deployment guide;
  A medicine packaging apparatus comprising:   The medicine packaging apparatus according to claim 1, wherein the first vibration applying mechanism includes a first vibration generation source and a holding structure that holds the first vibration generation source and the hopper. A powder supply unit,
The hopper extends obliquely downward from the charging opening toward the nozzle part, and has at least an inclined surface for conveying the powder charged from the powder supply part through the charging opening toward the nozzle part. Have one,
The holding structure is such that the hopper vibrates in an elliptical orbit away from the inclined surface toward the upper side in a plane including a moving direction in which the powder moves by gravity on the inclined surface and the direction of gravity. The medicine packaging apparatus according to claim 2, wherein the vibration of the first vibration generation source is transmitted to the hopper.   The medicine packaging apparatus according to claim 3, wherein an angle formed between a long axis of an elliptical orbit of vibration of the hopper and the moving direction in which the powder moves by its own weight on the inclined surface is an acute angle. The holding structure is
A hopper holding portion for holding the hopper;
A vibration source holding unit that holds the first vibration generation source provided on one end side of the hopper holding unit;
5. A leaf spring portion having an upper end connected to the hopper holding portion, a lower end side fixed, and a leaf spring portion extending obliquely downward from the hopper holding portion so as to approach the vibration source holding portion toward the lower end side. The medicine packaging device described. The vibration source holder is
A connecting portion extending downward from the one end side of the hopper holding portion;
The medicine packaging apparatus according to claim 5, further comprising: a main body that is provided at a lower end of the connecting portion and accommodates the first vibration generation source.   The medicine packaging apparatus according to claim 6, wherein the main body in which the first vibration generation source is accommodated is positioned adjacent to an upper end of the inclined surface of the hopper.   The medicine packaging apparatus according to any one of claims 1 to 7, wherein the second vibration applying mechanism includes a second vibration generation source fixed inside the deployment guide. The heat seal part includes a heat seal member that sandwiches the packaging sheet,
The medicine packaging apparatus according to claim 8, further comprising a controller that operates the first and second vibration generation sources for a predetermined time when the heat seal portion is in a predetermined state.   The controller determines whether the medicine in the medicine package being created is a powder or a tablet based on the input prescription information, and if the medicine pack being created is the powder, the medicine is the tablet The medicine packaging apparatus according to claim 9, wherein a time for operating the first and second vibration generation sources is set longer than the time period.   When the controller determines whether there is a medicine package for packaging only the tablet after the medicine package for packaging the powder in the same prescription based on the inputted prescription information, the medicine package for the tablet only is being created. 10. The medicine packaging device according to claim 9, wherein the first and second vibration sources are maintained in a stopped state.   The controller maintains the first and second vibration generation sources in a stopped state when determining that an empty medicine package that does not package the medicine is being created based on the input prescription information. The medicine packaging device according to any one of claims 11 to 11. A front-side holding part that is arranged in a storage chamber in the apparatus main body and extends to the front side of the apparatus main body, a side-side holding part that extends from one side end side of the front-side holding part to the back side, and the front-side holding A holding frame having a rotation connecting part that rotatably connects the other side end side of the part to the apparatus main body,
The sheet supply unit includes a sheet guide mechanism for guiding the packaging sheet unwound from the roll,
The roll, the printing unit, and a part of the sheet guide mechanism are disposed on the side-side holding unit of the holding frame,
The remaining part of the sheet guide mechanism, the deployment guide, the drug introduction part, and the heat seal part are arranged in the front side holding part of the holding frame. The medicine packaging device according to any one of claims 12 to 12.

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