JP5514101B2 - トロンビンレセプターアンタゴニストによる血小板凝集阻害を測定する方法 - Google Patents
トロンビンレセプターアンタゴニストによる血小板凝集阻害を測定する方法 Download PDFInfo
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- JP5514101B2 JP5514101B2 JP2010507552A JP2010507552A JP5514101B2 JP 5514101 B2 JP5514101 B2 JP 5514101B2 JP 2010507552 A JP2010507552 A JP 2010507552A JP 2010507552 A JP2010507552 A JP 2010507552A JP 5514101 B2 JP5514101 B2 JP 5514101B2
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- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
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| US20070243632A1 (en) * | 2003-07-08 | 2007-10-18 | Coller Barry S | Methods for measuring platelet reactivity of patients that have received drug eluting stents |
| WO2009152094A2 (en) * | 2008-06-09 | 2009-12-17 | Accumetrics, Inc. | Hubbed dual cannula device for closed container sampling systems |
| US8448499B2 (en) | 2008-12-23 | 2013-05-28 | C A Casyso Ag | Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method |
| EP2371284A1 (en) * | 2010-03-24 | 2011-10-05 | C A Casyso AG | Method and apparatus for determining at least one evaluation parameter of a blood sample |
| WO2011133450A2 (en) | 2010-04-19 | 2011-10-27 | Meso Scale Technologies, Llc. | Serology assays |
| DK2616550T3 (en) * | 2010-09-15 | 2016-05-23 | Debiopharm Int Sa | Process for Separating Target Molecules or Particles from Fibrinogen-Containing Samples Including Blood Components |
| RU2559873C2 (ru) * | 2011-04-27 | 2015-08-20 | Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) | Миметики поли (adp-рибозы) и способ их получения |
| CN103969228A (zh) * | 2013-02-04 | 2014-08-06 | 百奥泰生物科技(广州)有限公司 | 一种整合素GP IIb/IIIa特异性结合分子巴替非班的生物学效应检测方法 |
| EP3060233A4 (en) * | 2013-10-25 | 2017-04-12 | Bristol-Myers Squibb Company | Diagnostic methods for par4 antagonist therapy |
| US10539579B2 (en) | 2014-09-29 | 2020-01-21 | C A Casyso Gmbh | Blood testing system and method |
| CN105717263B (zh) * | 2016-03-04 | 2018-01-26 | 北京乐普医疗科技有限责任公司 | 一种检测噻吩并吡啶类抗血小板药物疗效的试剂卡及其使用方法和应用 |
| CN111788300B (zh) * | 2017-12-28 | 2024-08-13 | 株式会社钟化 | 细胞聚集抑制剂 |
| CN109884326B (zh) * | 2019-03-27 | 2022-08-19 | 深圳优迪生物技术有限公司 | 血小板聚集功能检测试剂盒 |
| CN110051692A (zh) * | 2019-04-12 | 2019-07-26 | 南京市第一医院 | 一种血小板定向释放生长因子的组合物及其制备方法 |
| US20220373566A1 (en) * | 2019-10-17 | 2022-11-24 | Nova Biomedical Corporation | Coagulation assay apparatus and methods thereof |
| CN116794333A (zh) * | 2022-12-22 | 2023-09-22 | 北京乐普诊断科技股份有限公司 | 一种全面激活血小板基础凝集功能的激活剂配方及其制备方法 |
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| US3518057A (en) * | 1966-04-22 | 1970-06-30 | Huron Road Hospital | Method and apparatus for thrombus formation time determinations |
| US3694161A (en) * | 1971-04-14 | 1972-09-26 | Armour Pharma | Method for measuring platelet aggregation |
| US4051236A (en) * | 1973-02-15 | 1977-09-27 | E. R. Squibb & Sons, Inc. | Inhibition of blood platelet aggregation |
| NO750542L (cg-RX-API-DMAC7.html) * | 1974-02-21 | 1975-08-22 | Braun Melsungen Ag | |
| CA1284642C (en) * | 1986-03-31 | 1991-06-04 | Hikozo Iwakura | Prostacyclin (pgi ) analogues |
| US5066592A (en) * | 1988-03-08 | 1991-11-19 | Temple University Of The Commonwealth System Of Higher Education | Trigramin - a platelet aggregation inhibiting polypeptide |
| US5023233A (en) * | 1989-07-28 | 1991-06-11 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| US5242810A (en) * | 1990-12-07 | 1993-09-07 | Biogen, Inc. | Bifunctional inhibitors of thrombin and platelet activation |
| US5763199A (en) * | 1994-09-29 | 1998-06-09 | Mount Sinai School Of Medicine Of The City University Of New York | Platelet blockade assay |
| US6221672B1 (en) * | 1996-04-30 | 2001-04-24 | Medtronic, Inc. | Method for determining platelet inhibitor response |
| US6043871A (en) * | 1997-03-03 | 2000-03-28 | Brigham Young University | System and method for measuring blood platelet function |
| US5922551A (en) * | 1997-03-20 | 1999-07-13 | Accumetrics, Inc. | Agglutrimetric platelet binding assays in blood |
| US6210904B1 (en) * | 1997-10-14 | 2001-04-03 | Merck & Co., Inc. | Anticoagulant test |
| US6063847A (en) * | 1997-11-25 | 2000-05-16 | Schering Corporation | Thrombin receptor antagonists |
| CA2321142A1 (en) * | 1998-02-27 | 1999-09-02 | Regents Of The University Of California | Protease-activated receptor 4 and uses thereof |
| ATE368659T1 (de) * | 2000-06-15 | 2007-08-15 | Schering Corp | Thrombinrezeptorantagonisten |
| ES2282304T3 (es) * | 2000-11-01 | 2007-10-16 | Astellas Pharma Inc. | Procedimiento para seleccionar antiplaquetas. |
| US6841354B2 (en) * | 2000-12-21 | 2005-01-11 | Philadelphia, Health & Education Corporation | Screening assay for anti-thrombotic/anti-platelet activity |
| US20040242627A1 (en) * | 2001-04-19 | 2004-12-02 | Shuichi Suzuki | 2-Iminoimidazole derivatives (1) |
| EP1493028A4 (en) * | 2001-07-06 | 2006-06-14 | Genentech Inc | PHAGEN DISPLAY PRESENTED LIGANDS OF THE PDZ DOMAIN |
| CA2463628A1 (en) * | 2001-10-18 | 2003-04-24 | Schering Corporation | Himbacine analogues as thrombin receptor antagonists |
| WO2004036226A1 (en) * | 2002-10-15 | 2004-04-29 | The University Of Tennessee Research Foundation | Methods for assessment of platelet aggregation |
| US20070243632A1 (en) * | 2003-07-08 | 2007-10-18 | Coller Barry S | Methods for measuring platelet reactivity of patients that have received drug eluting stents |
| ES2378544T3 (es) * | 2003-07-08 | 2012-04-13 | Accumetrics, Inc. | Activación selectiva de plaquetas para el seguimiento de terapia con antagonistas de ADP |
| US7595169B2 (en) * | 2005-04-27 | 2009-09-29 | Accumetrics, Inc. | Method for determining percent platelet aggregation |
| WO2007007588A1 (ja) * | 2005-07-08 | 2007-01-18 | Ono Pharmaceutical Co., Ltd. | 平面性を有する環状基を母核とする化合物 |
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| US20080299587A1 (en) | 2008-12-04 |
| KR20100017576A (ko) | 2010-02-16 |
| JP2010526319A (ja) | 2010-07-29 |
| EP2153235A1 (en) | 2010-02-17 |
| CN101675342A (zh) | 2010-03-17 |
| EP2153235B1 (en) | 2012-05-16 |
| KR20150051243A (ko) | 2015-05-11 |
| ES2387700T3 (es) | 2012-09-28 |
| JP2014052388A (ja) | 2014-03-20 |
| WO2008137673A1 (en) | 2008-11-13 |
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