JP5480819B2 - 選択的サブタイプアルファ２アドレナリンアゴニスト及びその使用方法 - Google Patents

選択的サブタイプアルファ２アドレナリンアゴニスト及びその使用方法 Download PDF

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JP5480819B2
JP5480819B2 JP2010543197A JP2010543197A JP5480819B2 JP 5480819 B2 JP5480819 B2 JP 5480819B2 JP 2010543197 A JP2010543197 A JP 2010543197A JP 2010543197 A JP2010543197 A JP 2010543197A JP 5480819 B2 JP5480819 B2 JP 5480819B2
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pain
compound
alpha
pyridin
disease
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JP2011510007A5 (https=
JP2011510007A (ja
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トッド エム ハイデルボー
ケン チャウ
サントーシュ シー シンハ
フォン エックス グエン
ウェンクイ ケイ ファン
リン リー
ジャネット エイ タケウチ
スミタ エス バート
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Allergan Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A—HUMAN NECESSITIES
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    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/48—Nitrogen atoms not forming part of a nitro radical with acyclic hydrocarbon or substituted acyclic hydrocarbon radicals, attached to said nitrogen atoms
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    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Addiction (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
JP2010543197A 2008-01-18 2009-01-14 選択的サブタイプアルファ２アドレナリンアゴニスト及びその使用方法 Expired - Fee Related JP5480819B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2215808P 2008-01-18 2008-01-18
US61/022,158 2008-01-18
PCT/US2009/030886 WO2009091759A1 (en) 2008-01-18 2009-01-14 Selective subtype alpha 2 adrenergic agents and methods for use thereof

Publications (3)

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JP2011510007A JP2011510007A (ja) 2011-03-31
JP2011510007A5 JP2011510007A5 (https=) 2012-03-01
JP5480819B2 true JP5480819B2 (ja) 2014-04-23

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JP2010543197A Expired - Fee Related JP5480819B2 (ja) 2008-01-18 2009-01-14 選択的サブタイプアルファ２アドレナリンアゴニスト及びその使用方法

Country Status (8)

Country Link
US (1) US8362022B2 (https=)
EP (1) EP2240468B1 (https=)
JP (1) JP5480819B2 (https=)
BR (1) BRPI0906925A2 (https=)
CA (1) CA2712262A1 (https=)
DK (1) DK2240468T3 (https=)
ES (1) ES2442298T3 (https=)
WO (1) WO2009091759A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8809379B2 (en) * 2008-01-18 2014-08-19 Allergan, Inc. Selective subtype alpha 2 adrenergic agents and methods for use thereof
EP2242753B1 (en) * 2008-01-18 2015-04-08 Allergan, Inc. Oxazolidine and thiazolidine selective subtype alpha 2 adrenergic agents and methods for use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO750876L (https=) * 1974-03-28 1975-09-30 Bayer Ag
JPS61158968A (ja) * 1984-12-29 1986-07-18 Daicel Chem Ind Ltd フエナシル誘導体
GB8610909D0 (en) * 1986-05-03 1986-06-11 Beecham Group Plc Compounds
US5212176A (en) 1990-06-29 1993-05-18 Abbott Laboratories R(+)-terazosin
WO2005005394A2 (en) * 2003-07-09 2005-01-20 F.Hoffmann-La Roche Ag Thiophenylaminoimidazolines as prostaglandin i2 antagonists
MXPA06006501A (es) 2003-12-23 2006-08-23 Basf Ag Compuestos de 1-(azolin-2-il)amino-1,2-difeniletano para combatir insectos, aracnidos y nematodos.
DE602005013793D1 (de) * 2004-07-27 2009-05-20 Astellas Pharma Inc Thiazolderivate mit vap-1-hemmender wirkung
WO2008123821A1 (en) * 2007-03-01 2008-10-16 Albireo Ab 4, 5-dihydro-lh-imidazol-2-amine derivatives for use in the treatment of respiratory, cardiovascular, neurological or gastrointestinal disorders

Also Published As

Publication number Publication date
CA2712262A1 (en) 2009-07-23
WO2009091759A1 (en) 2009-07-23
US8362022B2 (en) 2013-01-29
ES2442298T3 (es) 2014-02-11
DK2240468T3 (da) 2014-01-20
EP2240468A1 (en) 2010-10-20
AU2009205472A1 (en) 2009-07-23
EP2240468B1 (en) 2013-10-16
JP2011510007A (ja) 2011-03-31
BRPI0906925A2 (pt) 2019-09-24
US20110034517A1 (en) 2011-02-10

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