JP5413916B2 - 統合検定のための液体格納 - Google Patents

統合検定のための液体格納 Download PDF

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Publication number
JP5413916B2
JP5413916B2 JP2010525801A JP2010525801A JP5413916B2 JP 5413916 B2 JP5413916 B2 JP 5413916B2 JP 2010525801 A JP2010525801 A JP 2010525801A JP 2010525801 A JP2010525801 A JP 2010525801A JP 5413916 B2 JP5413916 B2 JP 5413916B2
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liquid
fluid
channel
storage area
microfluidic
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Japanese (ja)
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JP2010539511A (ja
JP2010539511A5 (enExample
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ビンセント リンダー,
デイビッド スタインミラー,
ジェイソン テイラー,
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OPKO Diagnostics LLC
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OPKO Diagnostics LLC
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/025Align devices or objects to ensure defined positions relative to each other
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0673Handling of plugs of fluid surrounded by immiscible fluid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/069Absorbents; Gels to retain a fluid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087Multiple sequential chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • B01L2300/161Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
JP2010525801A 2007-09-19 2008-08-22 統合検定のための液体格納 Active JP5413916B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99441207P 2007-09-19 2007-09-19
US60/994,412 2007-09-19
PCT/US2008/010022 WO2009038628A2 (en) 2007-09-19 2008-08-22 Liquid containment for integrated assays

Publications (3)

Publication Number Publication Date
JP2010539511A JP2010539511A (ja) 2010-12-16
JP2010539511A5 JP2010539511A5 (enExample) 2012-09-13
JP5413916B2 true JP5413916B2 (ja) 2014-02-12

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JP2010525801A Active JP5413916B2 (ja) 2007-09-19 2008-08-22 統合検定のための液体格納

Country Status (4)

Country Link
US (1) US9795697B2 (enExample)
EP (1) EP2197583A2 (enExample)
JP (1) JP5413916B2 (enExample)
WO (1) WO2009038628A2 (enExample)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102357352B (zh) 2004-01-26 2015-08-12 哈佛大学 流体递送系统和方法
US20080243309A2 (en) * 2006-05-08 2008-10-02 Auburn University Systems for and methods of characterizing reactions
GB2473425A (en) * 2009-09-03 2011-03-16 Vivacta Ltd Fluid Sample Collection Device
US8746285B2 (en) * 2009-09-04 2014-06-10 Auburn University Programmable fluidic droplet generation
GB201005191D0 (en) * 2010-03-26 2010-05-12 Cambridge Entpr Ltd Immunoassays,methods for carrying out immunoassays,immunoassay kits and method for manufacturing immunoassay kits
BR112012026406B1 (pt) 2010-04-16 2020-06-09 Opko Diagnostics Llc método de conduzir controle de qualidade para determinar anormalidades na operação de um sistema microfluídico
WO2011153139A1 (en) * 2010-06-01 2011-12-08 Greene's Energy Group, L.L.C. Wastewater treatment system and method
WO2011153122A2 (en) * 2010-06-01 2011-12-08 Waters Technologies Corporation Apparatus and methods for preparation and analysis of dried samples of a biological fluid
US9821318B2 (en) * 2010-09-26 2017-11-21 Da Yu Enterprises, L.L.C. Separation of analytes
ES2870529T3 (es) * 2010-12-09 2021-10-27 Abbott Point Of Care Inc Aparato que usa un agente anti-adsorción para facilitar la mezcla y el análisis de muestras
WO2013049348A2 (en) * 2011-09-27 2013-04-04 Diagnostics For All, Inc. Quantitative microfluidic devices
US8771611B2 (en) 2011-11-28 2014-07-08 Auburn University System and methods of log-scale concentration gradients
US20130211289A1 (en) 2012-01-25 2013-08-15 Tasso, Inc. Handheld Device for Drawing, Collecting, and Analyzing Bodily Fluid
CN104411406B (zh) 2012-03-16 2017-05-31 统计诊断与创新有限公司 具有集成传送模块的测试盒
WO2013177560A1 (en) 2012-05-25 2013-11-28 The Regents Of The University Of California Microfluidic systems for particle trapping and separation
US9976963B2 (en) * 2012-12-21 2018-05-22 Integrated Plasmonics Corporation Microcuvette cartridge
EP2969156B1 (en) * 2013-03-13 2019-04-10 Opko Diagnostics, LLC Mixing of fluids in fluidic systems
JP6477488B2 (ja) * 2013-10-31 2019-03-06 コニカミノルタ株式会社 検出装置および当該検出装置を用いた検出方法
US10779757B2 (en) * 2014-08-01 2020-09-22 Tasso, Inc. Devices, systems and methods for gravity-enhanced microfluidic collection, handling and transferring of fluids
WO2016019388A1 (en) 2014-08-01 2016-02-04 Tasso, Inc. Devices, systems and methods for gravity-enhanced microfluidic collection, handling and transferring of fluids
US10279345B2 (en) 2014-12-12 2019-05-07 Opko Diagnostics, Llc Fluidic systems comprising an incubation channel, including fluidic systems formed by molding
US10022720B2 (en) 2015-06-12 2018-07-17 Cytochip Inc. Fluidic units and cartridges for multi-analyte analysis
US10634602B2 (en) 2015-06-12 2020-04-28 Cytochip Inc. Fluidic cartridge for cytometry and additional analysis
CN108027310B (zh) 2015-07-14 2020-12-22 芯易诊有限公司 流体盒中的体积感测
US9862941B2 (en) 2015-10-14 2018-01-09 Pioneer Hi-Bred International, Inc. Single cell microfluidic device
JP6989496B2 (ja) 2015-10-16 2022-01-05 オプコ・ダイアグノスティクス・リミテッド・ライアビリティ・カンパニーOpko Diagnostics, Llc 患者の試料を得るための表面を準備するための物品および方法
US10852310B2 (en) 2015-12-11 2020-12-01 Opko Diagnostics, Llc Fluidic systems involving incubation of samples and/or reagents
AU2016381254B2 (en) 2015-12-29 2022-04-21 Opko Diagnostics, Llc Fluid collection device and related methods
CN107398307B (zh) * 2016-05-18 2023-07-25 博奥生物集团有限公司 一种集成化微流控芯片
CN106237524B (zh) * 2016-09-09 2019-05-03 深圳半岛医疗有限公司 治疗敏感性肌肤的手柄和设备
WO2018071448A1 (en) * 2016-10-11 2018-04-19 The Regents Of The University Of California Systems and methods to encapsulate and preserve organic matter for analysis
WO2018122856A1 (en) * 2016-12-29 2018-07-05 Dalibor Hodko An electrophoretic chip for electrophoretic applications
US11517901B2 (en) 2017-06-09 2022-12-06 The Regents Of The University Of California High-efficiency particle encapsulation in droplets with particle spacing and downstream droplet sorting
US10780438B2 (en) 2017-06-09 2020-09-22 The Regents Of The University Of California High-efficiency encapsulation in droplets based on hydrodynamic vortices control
US10293340B2 (en) 2017-10-11 2019-05-21 Fitbit, Inc. Microfluidic metering and delivery system
WO2019075409A1 (en) 2017-10-12 2019-04-18 The Regents Of The University Of California ISOLATION AND IDENTIFICATION WITHOUT MICROFLUIDIC LABEL OF CELLS USING FLUORESCENCE LIFE IMAGING (FLIM)
WO2019079787A1 (en) 2017-10-20 2019-04-25 The Regents Of The University Of California MICROFLUIDIC SYSTEMS AND METHODS FOR CELL TRANSFECTION VIA LIPOFLEX
US11499127B2 (en) 2017-10-20 2022-11-15 The Regents Of The University Of California Multi-layered microfluidic systems for in vitro large-scale perfused capillary networks
US11491487B2 (en) 2017-10-23 2022-11-08 Cytochip Inc. Devices and methods for measuring analytes and target particles
JP7207325B2 (ja) * 2017-12-13 2023-01-18 株式会社ニコン 流体デバイス
US20210162404A1 (en) * 2017-12-13 2021-06-03 The University Of Tokyo Fluid device
WO2019209273A1 (en) * 2018-04-24 2019-10-31 Hewlett-Packard Development Company, L.P. Microfluidic devices
US11931738B2 (en) 2018-04-24 2024-03-19 Hewlett-Packard Development Company, L.P. Sequenced droplet ejection to deliver fluids
CN108519373B (zh) * 2018-04-27 2024-03-15 广州万孚生物技术股份有限公司 一种化学发光微流控芯片及含其的分析仪器
CN108716938B (zh) * 2018-04-27 2024-06-07 广州万孚生物技术股份有限公司 一种液体定量装置及其应用
US12179199B2 (en) 2019-08-09 2024-12-31 The Regents Of The University Of California Microfluidic single-cell pairing array for studying cell-cell interactions in isolated compartments
CN113617399B (zh) * 2020-05-06 2025-03-04 苏州国科均豪生物科技有限公司 一次性注入的高效微流控检测芯片
CN111588907A (zh) * 2020-06-05 2020-08-28 南京工业大学 一种多功能异质结构微纤维的制备方法
US12220698B2 (en) * 2020-06-30 2025-02-11 Samsung Electronics Co., Ltd. Microfluidic chip, and apparatus and method for detecting biomolecules
CN116075347B (zh) * 2020-09-16 2025-11-18 沃特世科技公司 用于评估系统惰性的方法
US12472497B2 (en) * 2021-04-16 2025-11-18 The Regents Of The University Of California Recirculation mechanism using elastic membrane
TWI785636B (zh) 2021-06-07 2022-12-01 新加坡商克雷多生醫有限公司 檢測卡匣
WO2024137351A1 (en) 2022-12-19 2024-06-27 Anchorline Biolabs, Inc. Capillary partitioning microfluidics
NL2036036B1 (en) * 2023-09-21 2025-03-26 Deepcell Inc Cartridge interface features

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1211157A (en) 1982-11-22 1986-09-09 Richard L. Columbus Capillary transport device having means for increasing the viscosity of the transported liquid
US4918025A (en) * 1987-03-03 1990-04-17 Pb Diagnostic Systems, Inc. Self contained immunoassay element
US5045473A (en) * 1987-07-14 1991-09-03 Technicon Instruments Corporation Apparatus and method for the separation and/or formation of immicible liquid streams
US5286454A (en) 1989-04-26 1994-02-15 Nilsson Sven Erik Cuvette
GB8915512D0 (en) 1989-07-06 1989-08-23 Sec Dep For Health Silver enhanced gold-labelled immuno assay method
JPH03223674A (ja) * 1989-11-30 1991-10-02 Mochida Pharmaceut Co Ltd 反応容器
AU642444B2 (en) 1989-11-30 1993-10-21 Mochida Pharmaceutical Co., Ltd. Reaction vessel
US5458852A (en) * 1992-05-21 1995-10-17 Biosite Diagnostics, Inc. Diagnostic devices for the controlled movement of reagents without membranes
US5885527A (en) 1992-05-21 1999-03-23 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membrances
US6673533B1 (en) 1995-03-10 2004-01-06 Meso Scale Technologies, Llc. Multi-array multi-specific electrochemiluminescence testing
US6168948B1 (en) 1995-06-29 2001-01-02 Affymetrix, Inc. Miniaturized genetic analysis systems and methods
US6632619B1 (en) 1997-05-16 2003-10-14 The Governors Of The University Of Alberta Microfluidic system and methods of use
WO1999025475A1 (de) 1997-11-19 1999-05-27 Peter Miethe Vorrichtung zur sequentiellen ausgabe von fliessfähigen reagenzien
US7087148B1 (en) 1998-06-23 2006-08-08 Clinical Micro Sensors, Inc. Binding acceleration techniques for the detection of analytes
US6416642B1 (en) 1999-01-21 2002-07-09 Caliper Technologies Corp. Method and apparatus for continuous liquid flow in microscale channels using pressure injection, wicking, and electrokinetic injection
EP1054259A1 (en) 1999-05-19 2000-11-22 Remacle, José Method for the identification of a target compound
US6858185B1 (en) 1999-08-25 2005-02-22 Caliper Life Sciences, Inc. Dilutions in high throughput systems with a single vacuum source
AU2001252973A1 (en) 2000-04-17 2001-10-30 Purdue Research Foundation Biosensor and related method
US20020142618A1 (en) 2000-08-04 2002-10-03 Caliper Technologies Corp. Control of operation conditions within fluidic systems
US6610499B1 (en) 2000-08-31 2003-08-26 The Regents Of The University Of California Capillary array and related methods
AU2002249481A1 (en) * 2000-10-25 2002-08-12 Exiqon A/S Open substrate platforms suitable for analysis of biomolecules
US7524462B2 (en) * 2002-03-29 2009-04-28 Agilent Technologies, Inc. Capillary flow for a heterogenous assay in a micro-channel environment
US20050221281A1 (en) 2003-01-08 2005-10-06 Ho Winston Z Self-contained microfluidic biochip and apparatus
DE10315074A1 (de) 2003-04-02 2004-10-14 Clondiag Chip Technologies Gmbh Vorrichtung zur Vervielfältigung und zum Nachweis von Nukleinsäuren
JP2005003637A (ja) * 2003-06-16 2005-01-06 Yokogawa Electric Corp カートリッジ内の廃液処理方法およびその方法を用いた診断用カートリッジ
CN102357352B (zh) 2004-01-26 2015-08-12 哈佛大学 流体递送系统和方法
US8030057B2 (en) * 2004-01-26 2011-10-04 President And Fellows Of Harvard College Fluid delivery system and method
US8101431B2 (en) 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
US9477233B2 (en) 2004-07-02 2016-10-25 The University Of Chicago Microfluidic system with a plurality of sequential T-junctions for performing reactions in microdroplets
EP1611954A1 (en) 2004-07-03 2006-01-04 Roche Diagnostics GmbH Liquid reservoir connector
GB0426082D0 (en) 2004-11-26 2004-12-29 Norchip As A device for carrying out biological assays
JP2008538077A (ja) * 2005-03-16 2008-10-09 ユニバーシティ オブ シカゴ マイクロフルイディックシステム
JP4268955B2 (ja) * 2005-05-30 2009-05-27 株式会社日立ハイテクノロジーズ 化学分析装置
CA2610875A1 (en) 2005-06-06 2006-12-14 Decision Biomarkers, Inc. Assays based on liquid flow over arrays
JP4721414B2 (ja) * 2005-08-15 2011-07-13 キヤノン株式会社 反応カートリッジ、反応装置および反応カートリッジの溶液の移動方法
EP2041573B1 (en) * 2006-06-23 2019-09-04 PerkinElmer Health Sciences, Inc. Methods and devices for microfluidic point-of-care immunoassays

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Publication number Publication date
JP2010539511A (ja) 2010-12-16
WO2009038628A2 (en) 2009-03-26
EP2197583A2 (en) 2010-06-23
WO2009038628A3 (en) 2009-06-11
US9795697B2 (en) 2017-10-24
US20090075390A1 (en) 2009-03-19

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