JP5413916B2 - 統合検定のための液体格納 - Google Patents

統合検定のための液体格納 Download PDF

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Publication number
JP5413916B2
JP5413916B2 JP2010525801A JP2010525801A JP5413916B2 JP 5413916 B2 JP5413916 B2 JP 5413916B2 JP 2010525801 A JP2010525801 A JP 2010525801A JP 2010525801 A JP2010525801 A JP 2010525801A JP 5413916 B2 JP5413916 B2 JP 5413916B2
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liquid
fluid
channel
storage area
microfluidic
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Japanese (ja)
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JP2010539511A5 (cg-RX-API-DMAC7.html
JP2010539511A (ja
Inventor
ビンセント リンダー,
デイビッド スタインミラー,
ジェイソン テイラー,
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OPKO Diagnostics LLC
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OPKO Diagnostics LLC
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/025Align devices or objects to ensure defined positions relative to each other
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0673Handling of plugs of fluid surrounded by immiscible fluid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/069Absorbents; Gels to retain a fluid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087Multiple sequential chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • B01L2300/161Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
JP2010525801A 2007-09-19 2008-08-22 統合検定のための液体格納 Active JP5413916B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99441207P 2007-09-19 2007-09-19
US60/994,412 2007-09-19
PCT/US2008/010022 WO2009038628A2 (en) 2007-09-19 2008-08-22 Liquid containment for integrated assays

Publications (3)

Publication Number Publication Date
JP2010539511A JP2010539511A (ja) 2010-12-16
JP2010539511A5 JP2010539511A5 (cg-RX-API-DMAC7.html) 2012-09-13
JP5413916B2 true JP5413916B2 (ja) 2014-02-12

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JP2010525801A Active JP5413916B2 (ja) 2007-09-19 2008-08-22 統合検定のための液体格納

Country Status (4)

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US (1) US9795697B2 (cg-RX-API-DMAC7.html)
EP (1) EP2197583A2 (cg-RX-API-DMAC7.html)
JP (1) JP5413916B2 (cg-RX-API-DMAC7.html)
WO (1) WO2009038628A2 (cg-RX-API-DMAC7.html)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005209321B2 (en) 2004-01-26 2010-11-18 President And Fellows Of Harvard College Fluid delivery system and method
US20080243309A2 (en) * 2006-05-08 2008-10-02 Auburn University Systems for and methods of characterizing reactions
GB2473425A (en) * 2009-09-03 2011-03-16 Vivacta Ltd Fluid Sample Collection Device
US8746285B2 (en) * 2009-09-04 2014-06-10 Auburn University Programmable fluidic droplet generation
GB201005191D0 (en) * 2010-03-26 2010-05-12 Cambridge Entpr Ltd Immunoassays,methods for carrying out immunoassays,immunoassay kits and method for manufacturing immunoassay kits
AU2011239538B2 (en) 2010-04-16 2014-10-23 Opko Diagnostics, Llc Systems and devices for analysis of samples
WO2011153122A2 (en) * 2010-06-01 2011-12-08 Waters Technologies Corporation Apparatus and methods for preparation and analysis of dried samples of a biological fluid
CA2798494A1 (en) * 2010-06-01 2011-12-08 Greene's Energy Group, L.L.C. Wastewater treatment system and method
EP2618935B1 (en) * 2010-09-26 2018-11-07 Da Yu Enterprises, L.L.C. Separation of analytes
JP5722458B2 (ja) * 2010-12-09 2015-05-20 アボット ポイント オブ ケア インコーポレイテッド 試料の混合及び分析を容易にするために抗吸着剤を使用する装置及び方法
CA2849980A1 (en) * 2011-09-27 2013-04-04 Diagnostics For All, Inc. Quantitative microfluidic devices
US8771611B2 (en) 2011-11-28 2014-07-08 Auburn University System and methods of log-scale concentration gradients
US20130211289A1 (en) 2012-01-25 2013-08-15 Tasso, Inc. Handheld Device for Drawing, Collecting, and Analyzing Bodily Fluid
CN106964411B (zh) 2012-03-16 2019-12-10 统计诊断与创新有限公司 具有集成传送模块的测试盒
US10564147B2 (en) 2012-05-25 2020-02-18 The Regents Of The University Of California Microfluidic systems for particle trapping and separation using cavity acoustic transducers
US9976963B2 (en) * 2012-12-21 2018-05-22 Integrated Plasmonics Corporation Microcuvette cartridge
US9588027B2 (en) 2013-03-13 2017-03-07 UPKO Diagnostics, LLC Mixing of fluids in fluidic systems
WO2015064757A1 (ja) * 2013-10-31 2015-05-07 コニカミノルタ株式会社 検出装置、当該検出装置を用いた検出方法および当該検出装置に用いられる検出チップ
US10779757B2 (en) * 2014-08-01 2020-09-22 Tasso, Inc. Devices, systems and methods for gravity-enhanced microfluidic collection, handling and transferring of fluids
AU2015295983B2 (en) * 2014-08-01 2020-04-30 Tasso, Inc. Devices, systems and methods for gravity-enhanced microfluidic collection, handling and transferring of fluids
CN107206376B (zh) * 2014-12-12 2021-07-09 欧普科诊断有限责任公司 包括通过模塑形成之流控系统的包含孵育通道的流控系统
US10634602B2 (en) 2015-06-12 2020-04-28 Cytochip Inc. Fluidic cartridge for cytometry and additional analysis
EP3307670B1 (en) 2015-06-12 2020-12-09 Cytochip Inc. Fluidic units and cartridges for multi-analyte analysis
EP3322968B1 (en) 2015-07-14 2024-02-21 Cytochip Inc. Volume sensing in a fluidic cartridge
US9862941B2 (en) 2015-10-14 2018-01-09 Pioneer Hi-Bred International, Inc. Single cell microfluidic device
JP6989496B2 (ja) 2015-10-16 2022-01-05 オプコ・ダイアグノスティクス・リミテッド・ライアビリティ・カンパニーOpko Diagnostics, Llc 患者の試料を得るための表面を準備するための物品および方法
US10852310B2 (en) 2015-12-11 2020-12-01 Opko Diagnostics, Llc Fluidic systems involving incubation of samples and/or reagents
CA3006882C (en) 2015-12-29 2023-11-28 Opko Diagnostics, Llc Fluid collection device and related methods
CN107398307B (zh) * 2016-05-18 2023-07-25 博奥生物集团有限公司 一种集成化微流控芯片
CN106237524B (zh) * 2016-09-09 2019-05-03 深圳半岛医疗有限公司 治疗敏感性肌肤的手柄和设备
WO2018071448A1 (en) * 2016-10-11 2018-04-19 The Regents Of The University Of California Systems and methods to encapsulate and preserve organic matter for analysis
WO2018122856A1 (en) 2016-12-29 2018-07-05 Dalibor Hodko An electrophoretic chip for electrophoretic applications
WO2018227210A1 (en) 2017-06-09 2018-12-13 The Regents Of The University Of California High-efficiency encapsulation in droplets based on hydrodynamic vortices control
US11517901B2 (en) 2017-06-09 2022-12-06 The Regents Of The University Of California High-efficiency particle encapsulation in droplets with particle spacing and downstream droplet sorting
US10293340B2 (en) 2017-10-11 2019-05-21 Fitbit, Inc. Microfluidic metering and delivery system
WO2019075409A1 (en) 2017-10-12 2019-04-18 The Regents Of The University Of California ISOLATION AND IDENTIFICATION WITHOUT MICROFLUIDIC LABEL OF CELLS USING FLUORESCENCE LIFE IMAGING (FLIM)
US11499127B2 (en) 2017-10-20 2022-11-15 The Regents Of The University Of California Multi-layered microfluidic systems for in vitro large-scale perfused capillary networks
US11745179B2 (en) 2017-10-20 2023-09-05 The Regents Of The University Of California Microfluidic systems and methods for lipoplex-mediated cell transfection
US11491487B2 (en) 2017-10-23 2022-11-08 Cytochip Inc. Devices and methods for measuring analytes and target particles
JP7157421B2 (ja) * 2017-12-13 2022-10-20 国立大学法人 東京大学 流体デバイス
US11369959B2 (en) * 2017-12-13 2022-06-28 Nikon Corporation Fluidic device
US20210031188A1 (en) 2018-04-24 2021-02-04 Hewlett-Packard Development Company, L.P. Droplet ejectors to draw fluids through microfluidic networks
US11925932B2 (en) * 2018-04-24 2024-03-12 Hewlett-Packard Development Company, L.P. Microfluidic devices
CN108716938B (zh) * 2018-04-27 2024-06-07 广州万孚生物技术股份有限公司 一种液体定量装置及其应用
CN108519373B (zh) * 2018-04-27 2024-03-15 广州万孚生物技术股份有限公司 一种化学发光微流控芯片及含其的分析仪器
US12179199B2 (en) 2019-08-09 2024-12-31 The Regents Of The University Of California Microfluidic single-cell pairing array for studying cell-cell interactions in isolated compartments
CN113617399B (zh) * 2020-05-06 2025-03-04 苏州国科均豪生物科技有限公司 一次性注入的高效微流控检测芯片
CN111588907A (zh) * 2020-06-05 2020-08-28 南京工业大学 一种多功能异质结构微纤维的制备方法
US12220698B2 (en) * 2020-06-30 2025-02-11 Samsung Electronics Co., Ltd. Microfluidic chip, and apparatus and method for detecting biomolecules
CN116075347B (zh) * 2020-09-16 2025-11-18 沃特世科技公司 用于评估系统惰性的方法
US12472497B2 (en) * 2021-04-16 2025-11-18 The Regents Of The University Of California Recirculation mechanism using elastic membrane
TWI785636B (zh) 2021-06-07 2022-12-01 新加坡商克雷多生醫有限公司 檢測卡匣
EP4638006A1 (en) 2022-12-19 2025-10-29 Anchorline Biolabs, Inc. Capillary partitioning microfluidics
NL2036036B1 (en) * 2023-09-21 2025-03-26 Deepcell Inc Cartridge interface features

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1211157A (en) 1982-11-22 1986-09-09 Richard L. Columbus Capillary transport device having means for increasing the viscosity of the transported liquid
US4918025A (en) * 1987-03-03 1990-04-17 Pb Diagnostic Systems, Inc. Self contained immunoassay element
US5045473A (en) * 1987-07-14 1991-09-03 Technicon Instruments Corporation Apparatus and method for the separation and/or formation of immicible liquid streams
US5286454A (en) 1989-04-26 1994-02-15 Nilsson Sven Erik Cuvette
GB8915512D0 (en) 1989-07-06 1989-08-23 Sec Dep For Health Silver enhanced gold-labelled immuno assay method
AU642444B2 (en) 1989-11-30 1993-10-21 Mochida Pharmaceutical Co., Ltd. Reaction vessel
JPH03223674A (ja) * 1989-11-30 1991-10-02 Mochida Pharmaceut Co Ltd 反応容器
US5458852A (en) * 1992-05-21 1995-10-17 Biosite Diagnostics, Inc. Diagnostic devices for the controlled movement of reagents without membranes
US5885527A (en) 1992-05-21 1999-03-23 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membrances
US6673533B1 (en) 1995-03-10 2004-01-06 Meso Scale Technologies, Llc. Multi-array multi-specific electrochemiluminescence testing
US6168948B1 (en) 1995-06-29 2001-01-02 Affymetrix, Inc. Miniaturized genetic analysis systems and methods
US6632619B1 (en) 1997-05-16 2003-10-14 The Governors Of The University Of Alberta Microfluidic system and methods of use
ATE216637T1 (de) 1997-11-19 2002-05-15 Biognosis Gmbh Vorrichtung zur sequentiellen ausgabe von fliessfähigen reagenzien
US7087148B1 (en) 1998-06-23 2006-08-08 Clinical Micro Sensors, Inc. Binding acceleration techniques for the detection of analytes
US6416642B1 (en) 1999-01-21 2002-07-09 Caliper Technologies Corp. Method and apparatus for continuous liquid flow in microscale channels using pressure injection, wicking, and electrokinetic injection
EP1054259A1 (en) 1999-05-19 2000-11-22 Remacle, José Method for the identification of a target compound
US6858185B1 (en) 1999-08-25 2005-02-22 Caliper Life Sciences, Inc. Dilutions in high throughput systems with a single vacuum source
EP1283900A4 (en) 2000-04-17 2006-02-08 Purdue Research Foundation BIOSENSOR AND CORRESPONDING METHOD
US20020142618A1 (en) 2000-08-04 2002-10-03 Caliper Technologies Corp. Control of operation conditions within fluidic systems
US6610499B1 (en) 2000-08-31 2003-08-26 The Regents Of The University Of California Capillary array and related methods
WO2002061387A2 (en) * 2000-10-25 2002-08-08 Exiqon A/S Open substrate platforms suitable for analysis of biomolecules
US7524462B2 (en) * 2002-03-29 2009-04-28 Agilent Technologies, Inc. Capillary flow for a heterogenous assay in a micro-channel environment
US20050221281A1 (en) 2003-01-08 2005-10-06 Ho Winston Z Self-contained microfluidic biochip and apparatus
DE10315074A1 (de) 2003-04-02 2004-10-14 Clondiag Chip Technologies Gmbh Vorrichtung zur Vervielfältigung und zum Nachweis von Nukleinsäuren
JP2005003637A (ja) * 2003-06-16 2005-01-06 Yokogawa Electric Corp カートリッジ内の廃液処理方法およびその方法を用いた診断用カートリッジ
AU2005209321B2 (en) * 2004-01-26 2010-11-18 President And Fellows Of Harvard College Fluid delivery system and method
US8030057B2 (en) * 2004-01-26 2011-10-04 President And Fellows Of Harvard College Fluid delivery system and method
US8101431B2 (en) 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
US9477233B2 (en) 2004-07-02 2016-10-25 The University Of Chicago Microfluidic system with a plurality of sequential T-junctions for performing reactions in microdroplets
EP1611954A1 (en) 2004-07-03 2006-01-04 Roche Diagnostics GmbH Liquid reservoir connector
GB0426082D0 (en) 2004-11-26 2004-12-29 Norchip As A device for carrying out biological assays
JP2008538077A (ja) * 2005-03-16 2008-10-09 ユニバーシティ オブ シカゴ マイクロフルイディックシステム
JP4268955B2 (ja) * 2005-05-30 2009-05-27 株式会社日立ハイテクノロジーズ 化学分析装置
EP1888235A1 (en) 2005-06-06 2008-02-20 Decision Biomarkers Incorporated Assays based on liquid flow over arrays
JP4721414B2 (ja) * 2005-08-15 2011-07-13 キヤノン株式会社 反応カートリッジ、反応装置および反応カートリッジの溶液の移動方法
WO2008002462A2 (en) * 2006-06-23 2008-01-03 Micronics, Inc. Methods and devices for microfluidic point-of-care immunoassays

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Publication number Publication date
WO2009038628A3 (en) 2009-06-11
EP2197583A2 (en) 2010-06-23
US20090075390A1 (en) 2009-03-19
WO2009038628A2 (en) 2009-03-26
JP2010539511A (ja) 2010-12-16
US9795697B2 (en) 2017-10-24

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