JP5393798B2 - リポタンパク質インスリン抵抗性指数、ならびに同一物を生成するための関連する方法、システムおよびコンピュータプログラム - Google Patents
リポタンパク質インスリン抵抗性指数、ならびに同一物を生成するための関連する方法、システムおよびコンピュータプログラム Download PDFInfo
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- JP5393798B2 JP5393798B2 JP2011532094A JP2011532094A JP5393798B2 JP 5393798 B2 JP5393798 B2 JP 5393798B2 JP 2011532094 A JP2011532094 A JP 2011532094A JP 2011532094 A JP2011532094 A JP 2011532094A JP 5393798 B2 JP5393798 B2 JP 5393798B2
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- Prior art keywords
- lipoprotein
- insulin resistance
- risk
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- sample
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/46—NMR spectroscopy
- G01R33/465—NMR spectroscopy applied to biological material, e.g. in vitro testing
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/104165—Lipid, cholesterol, or triglyceride standard or control
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- High Energy & Nuclear Physics (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10683308P | 2008-10-20 | 2008-10-20 | |
| US61/106,833 | 2008-10-20 | ||
| PCT/US2009/005689 WO2010047767A2 (en) | 2008-10-20 | 2009-10-20 | Lipoprotein insulin resistance indexes and related methods, systems and computer programs for generating same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012506051A JP2012506051A (ja) | 2012-03-08 |
| JP2012506051A5 JP2012506051A5 (https=) | 2012-12-06 |
| JP5393798B2 true JP5393798B2 (ja) | 2014-01-22 |
Family
ID=42109358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011532094A Active JP5393798B2 (ja) | 2008-10-20 | 2009-10-20 | リポタンパク質インスリン抵抗性指数、ならびに同一物を生成するための関連する方法、システムおよびコンピュータプログラム |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8386187B2 (https=) |
| EP (2) | EP2344890B1 (https=) |
| JP (1) | JP5393798B2 (https=) |
| KR (1) | KR20110086074A (https=) |
| AU (1) | AU2009308124B2 (https=) |
| CA (1) | CA2741034C (https=) |
| WO (1) | WO2010047767A2 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20110086074A (ko) | 2008-10-20 | 2011-07-27 | 리포사이언스, 인크. | 지질단백질 인슐린 저항성 지표 및 이와 관련된 방법, 시스템 및 이를 생성하기 위한 컴퓨터 프로그램 |
| SG10201608139VA (en) * | 2011-06-30 | 2016-11-29 | Liposcience Inc | Quantitative nmr clinical analyzers with automatic nmr temperature sensitivity compensation that accommodate large ambient operational temperature ranges |
| TWI596494B (zh) | 2012-03-05 | 2017-08-21 | Opko診斷法有限責任公司 | 預測前列腺癌風險及前列腺腺體體積之方法及裝置 |
| US9483612B2 (en) | 2012-04-27 | 2016-11-01 | Liposcience, Inc. | CHD risk stratification evaluations for subjects with high levels of large HDL-P |
| US9361429B2 (en) * | 2012-06-08 | 2016-06-07 | Liposcience, Inc. | Multi-parameter diabetes risk evaluations |
| US9928345B2 (en) | 2012-06-08 | 2018-03-27 | Liposciences, Inc. | Multiple-marker risk parameters predictive of conversion to diabetes |
| US9470771B2 (en) | 2012-06-08 | 2016-10-18 | Liposcience, Inc. | NMR measurements of NMR biomarker GlycA |
| US9551768B2 (en) | 2013-03-15 | 2017-01-24 | East Carolina University | NMR method for monitoring changes in the core of lipoprotein particles in metabolism and disease |
| CA2931648C (en) * | 2014-01-06 | 2022-11-29 | Liposcience, Inc. | Multiple-marker risk parameters predictive of conversion to diabetes |
| KR102505543B1 (ko) | 2014-03-28 | 2023-03-02 | 옵코 다이어그노스틱스, 엘엘씨 | 전립선암 진단에 관한 조성물 및 방법 |
| US12326453B2 (en) | 2014-03-28 | 2025-06-10 | Opko Diagnostics, Llc | Compositions and methods for active surveillance of prostate cancer |
| US9952232B2 (en) | 2014-09-11 | 2018-04-24 | Liposcience, Inc. | Cardiovascular risk evaluations using a risk parameter that includes an HDL and inflammatory biomarker interaction parameter |
| WO2016123163A2 (en) | 2015-01-27 | 2016-08-04 | Kardiatonos, Inc. | Biomarkers of vascular disease |
| PT3253800T (pt) | 2015-03-27 | 2021-04-28 | Opko Diagnostics Llc | Padrões de antigénio da próstata e suas utilizações |
| KR102539142B1 (ko) | 2016-09-05 | 2023-06-01 | 삼성전자주식회사 | 스펙트럼 분석 장치와 방법, 및 혈당 측정 장치 |
| US10775458B2 (en) | 2018-03-05 | 2020-09-15 | Texas Tech University System | Method and system for non-invasive measurement of metabolic health |
| US12289368B2 (en) * | 2020-10-29 | 2025-04-29 | Telefonaktiebolaget Lm Ericsson (Publ) | Checking state consistency in a log replication configuration |
| CN113117241B (zh) * | 2021-04-15 | 2022-01-28 | 中国科学院合肥物质科学研究院 | 一种提高胰岛素水平和敏感性的磁场发生装置及其应用 |
| CN115188493A (zh) * | 2022-07-13 | 2022-10-14 | 天津市人民医院 | 一种胰岛素抵抗预测模型的构建系统、方法及应用 |
| WO2024097429A1 (en) * | 2022-11-05 | 2024-05-10 | Texas Tech University System | Methods and tools for assessing cardiometabolic health and hidden disease risk among apparently healthy individuals |
| CN120613144B (zh) * | 2025-05-27 | 2026-02-03 | 中国科学院精密测量科学与技术创新研究院 | 一种基于血液nmr编辑谱的药物敏感度预测方法 |
| CN120280166A (zh) * | 2025-06-10 | 2025-07-08 | 南昌大学第二附属医院 | 术后胰岛素抵抗风险预测模型的构建方法及系统 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4933844A (en) | 1988-09-26 | 1990-06-12 | Otvos James D | Measurement of blood lipoprotein constituents by analysis of data acquired from an NMR spectrometer |
| WO1993003450A1 (en) | 1991-07-30 | 1993-02-18 | North Carolina State University | Method and apparatus for measuring blood lipoprotein levels by nmr spectroscopy |
| US6653140B2 (en) * | 1999-02-26 | 2003-11-25 | Liposcience, Inc. | Methods for providing personalized lipoprotein-based risk assessments |
| EP1171778B1 (en) * | 1999-04-22 | 2006-03-01 | Liposcience, Inc. | Nmr-method for determining the risk of developing type 2 diabetes |
| US7395158B2 (en) * | 2000-05-30 | 2008-07-01 | Sensys Medical, Inc. | Method of screening for disorders of glucose metabolism |
| US6890905B2 (en) * | 2001-04-02 | 2005-05-10 | Prosidion Limited | Methods for improving islet signaling in diabetes mellitus and for its prevention |
| WO2003012416A1 (en) * | 2001-08-01 | 2003-02-13 | Liposcience, Inc. | Method of determining presence and concentration of lipoprotein x in blood plasma and serum |
| CA2467420A1 (en) * | 2001-11-13 | 2003-05-22 | The Regents Of The University Of California | Ion mobility analysis of biological particles |
| WO2004040407A2 (en) | 2002-10-25 | 2004-05-13 | Liposcience, Inc. | Methods, systems and computer programs for deconvolving the spectral contribution of chemical constituents with overlapping signals |
| DE10315877B4 (de) * | 2003-04-08 | 2005-11-17 | Roche Diagnostics Gmbh | Krankheitsverlaufkontrolle |
| FR2853911B1 (fr) * | 2003-04-17 | 2005-07-08 | Merck Sante Sas | Gene induit par l'insuline, comme cible therapeutique dans le diabete |
| ES2556164T3 (es) * | 2003-09-23 | 2016-01-13 | The General Hospital Corporation | Cribado de la preeclampsia |
| WO2005098463A2 (en) * | 2004-04-01 | 2005-10-20 | Liposcience, Inc. | Nmr clinical analyzers and related methods, systems, modules and computer program products for clinical evaluation of biosamples |
| ES2571929T3 (es) * | 2004-05-26 | 2016-05-27 | Region Nordjylland | Procedimiento para determinar la cantidad de CD36 circulante |
| DE102004026903B4 (de) * | 2004-06-01 | 2006-05-18 | Universität Regensburg | Verfahren zur Bestimmung von Lipoproteinen in Körperflüssigkeiten und Messanordnung dafür |
| WO2006014678A2 (en) * | 2004-07-20 | 2006-02-09 | Genentech, Inc. | Compositions and methods of using angiopoietin-like 4 protein |
| JP4210855B2 (ja) * | 2004-09-28 | 2009-01-21 | 大塚製薬株式会社 | インスリン抵抗性の評価方法 |
| US7323296B2 (en) * | 2004-10-01 | 2008-01-29 | Yuanhong Ma | Method and index for diagnosing insulin resistance |
| EP1645877A1 (en) * | 2004-10-08 | 2006-04-12 | Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO | Method for providing a insulin resistance biomarker profile of one or more lipids |
| WO2006110082A1 (en) * | 2005-04-11 | 2006-10-19 | Astrazeneca Ab | A method and a kit for diagnosing type 2 diabetes, metabolic syndrome, sub clinical atherosclerosis, myocardial infarct, stroke or clinical manifestations of diabetes. |
| WO2007133593A2 (en) * | 2006-05-10 | 2007-11-22 | Liposcience, Inc. | Methods, systems and computer programs for assessing chd risk using weighted hdl particle number measurements |
| MX2010000414A (es) * | 2007-07-17 | 2010-04-01 | Metabolon Inc | Biomarcadores para prediabetes, enfermedades cardiovasculares y otros trastornos relacionados con sindrome metabolico, y metodos de uso de los mismos. |
| US20090191576A1 (en) * | 2008-01-28 | 2009-07-30 | Yuanhong Ma | Method and index for diagnosing insulin resistance |
| KR20110086074A (ko) | 2008-10-20 | 2011-07-27 | 리포사이언스, 인크. | 지질단백질 인슐린 저항성 지표 및 이와 관련된 방법, 시스템 및 이를 생성하기 위한 컴퓨터 프로그램 |
-
2009
- 2009-10-20 KR KR1020117011307A patent/KR20110086074A/ko not_active Ceased
- 2009-10-20 WO PCT/US2009/005689 patent/WO2010047767A2/en not_active Ceased
- 2009-10-20 EP EP09822305.0A patent/EP2344890B1/en active Active
- 2009-10-20 AU AU2009308124A patent/AU2009308124B2/en not_active Expired - Fee Related
- 2009-10-20 US US12/582,259 patent/US8386187B2/en active Active
- 2009-10-20 JP JP2011532094A patent/JP5393798B2/ja active Active
- 2009-10-20 EP EP21190653.2A patent/EP4016105A1/en not_active Ceased
- 2009-10-20 CA CA2741034A patent/CA2741034C/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010047767A2 (en) | 2010-04-29 |
| US8386187B2 (en) | 2013-02-26 |
| WO2010047767A3 (en) | 2010-08-26 |
| CA2741034A1 (en) | 2010-04-29 |
| US20100100334A1 (en) | 2010-04-22 |
| CA2741034C (en) | 2021-06-22 |
| EP2344890A2 (en) | 2011-07-20 |
| EP2344890A4 (en) | 2012-12-26 |
| EP2344890B1 (en) | 2021-08-11 |
| EP4016105A1 (en) | 2022-06-22 |
| KR20110086074A (ko) | 2011-07-27 |
| AU2009308124A1 (en) | 2010-04-29 |
| JP2012506051A (ja) | 2012-03-08 |
| AU2009308124B2 (en) | 2014-12-11 |
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