JP5323717B2 - 有機ナノ構造体アレイの形成 - Google Patents
有機ナノ構造体アレイの形成 Download PDFInfo
- Publication number
- JP5323717B2 JP5323717B2 JP2009539870A JP2009539870A JP5323717B2 JP 5323717 B2 JP5323717 B2 JP 5323717B2 JP 2009539870 A JP2009539870 A JP 2009539870A JP 2009539870 A JP2009539870 A JP 2009539870A JP 5323717 B2 JP5323717 B2 JP 5323717B2
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- nanostructure
- nanostructures
- peptides
- array
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
- B81C1/00—Manufacture or treatment of devices or systems in or on a substrate
- B81C1/00015—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
- B81C1/00023—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems without movable or flexible elements
- B81C1/00031—Regular or irregular arrays of nanoscale structures, e.g. etch mask layer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/14—Peptides being immobilised on, or in, an inorganic carrier
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00709—Type of synthesis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
- B81B2203/00—Basic microelectromechanical structures
- B81B2203/03—Static structures
- B81B2203/0361—Tips, pillars
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
- B81C2201/00—Manufacture or treatment of microstructural devices or systems
- B81C2201/01—Manufacture or treatment of microstructural devices or systems in or on a substrate
- B81C2201/0101—Shaping material; Structuring the bulk substrate or layers on the substrate; Film patterning
- B81C2201/0147—Film patterning
- B81C2201/0149—Forming nanoscale microstructures using auto-arranging or self-assembling material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y25/00—Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y40/00—Manufacture or treatment of nanostructures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/788—Of specified organic or carbon-based composition
- Y10S977/789—Of specified organic or carbon-based composition in array format
- Y10S977/79—Of specified organic or carbon-based composition in array format with heterogeneous nanostructures
- Y10S977/791—Molecular array
- Y10S977/793—Protein array
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/84—Manufacture, treatment, or detection of nanostructure
- Y10S977/895—Manufacture, treatment, or detection of nanostructure having step or means utilizing chemical property
- Y10S977/896—Chemical synthesis, e.g. chemical bonding or breaking
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nanotechnology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Manufacturing & Machinery (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Physics & Mathematics (AREA)
- Composite Materials (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Materials Engineering (AREA)
- Crystallography & Structural Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Electrotherapy Devices (AREA)
- Liquid Deposition Of Substances Of Which Semiconductor Devices Are Composed (AREA)
Description
式中、C*は、D配置またはL配置を有するキラル炭素である;R1およびR2はそれぞれが独立して、水素、アルキル、シクロアルキル、アリール、カルボキシ、チオカルボキシ、C−カルボキシラートおよびC−チオカルボキシラートからなる群から選択される;R3は、ヒドロキシ、アルコキシ、アリールオキシ、チオヒドロキシ、チオアルコキシ、チオアリールオキシ、ハロおよびアミンからなる群から選択される;R4〜R7のそれぞれは独立して、水素、アルキル、シクロアルキル、アリール、ヘテロアリール、ヘテロ脂環式、ヒドロキシ、チオヒドロキシ(チオール)、アルコキシ、アリールオキシ、チオアルコキシ、チオアリールオキシ、C−カルボキシラート、C−チオカルボキシラート、N−カルバマート、N−チオカルバマート、ヒドラジン、グアニルおよびグアニジンからなる群から選択され(これらの用語は本明細書中で定義される通りである)、ただし、R4〜R7の少なくとも1つが、本明細書中上記において定義されるような芳香族成分を含む。
垂直に並べられた芳香族ジペプチドナノ構造体
垂直に並べられた芳香族ジペプチドナノ構造体のアレイの形成が下記において例示される。
ジフェニルアラニンおよびジフェニルアラニンペプチドアナログをBachem(Bubendorf、スイス)から購入した。ジフェニルアラニンペプチドおよびアナログの新鮮な溶液を、ペプチドの凍結乾燥形態を1,1,1,3,3,3−ヘキサフルオロ−2−プロパノール(HFP、Sigma)に溶解することによって調製した。何らかの事前の凝集を避けるために、新鮮なストック溶液をそれぞれの実験のために調製した。
下記のペプチド濃度が結果の節に示される(図12を参照のこと):20mg/ml、40mg/ml、60mg/ml、80mg/ml、120mg/mlおよび180mg/ml。
基体表面に形成された薄い層のSEM分析により、ペプチドナノ構造体の垂直に並べられたアレイが形成されたことが明らかにされた(図7b)。この実験でのペプチドナノ構造体は管状の形状を有していた。このペプチドナノ構造体はこの実験ではペプチドナノチューブとして示される。
水平に並べられた芳香族ジペプチドナノ構造体
本発明者らは、水平に並べられた芳香族ジペプチドナノ構造体のアレイを形成するために本発明の実施形態の方法を首尾良く用いた。このアレイを形成するために、磁場を加えた。カーボンナノチューブおよび無機ナノ粒子を並べるための磁場の使用が広範囲に研究される[30]が、有機ナノ構造体との磁場の使用は大きな課題をもたらしている。
ジフェニルアラニンおよびジフェニルアラニンペプチドアナログをBachem(Bubendorf、スイス)から購入した。ジフェニルアラニンペプチドおよびアナログの新鮮な溶液を、ペプチドの凍結乾燥形態を1,1,1,3,3,3−ヘキサフルオロ−2−プロパノール(HFP、Sigma)に溶解することによって調製した。何らかの事前の凝集を避けるために、新鮮なストック溶液をそれぞれの実験のために調製した。
ジフェニルアラニンペプチドの新鮮なストック溶液をHFPに溶解して100mg/mLの濃度にした。その後、ストック溶液を、水に希釈された20%の強磁性流体(EMG508、Ferrotec Corporation)における2mg/mLの最終濃度に希釈した。この市販されている水系強磁性流体は、10nmの特性直径を有する1.07%のマグネタイト(Fe3O4)粒子を、安定化されたアニオン性界面活性剤の存在下で有する。
図10a〜図10gは、強磁性流体の存在下における、ジフェニルアラニンに基づくペプチドナノチューブの自己集合、および、それらを外部磁場にさらすことにより、それらの水平アラインメントの制御がもたらされたことを示す。
Claims (9)
- ナノ構造体アレイを含むデバイスであって、前記ナノ構造体アレイが、基体と、少なくとも10個の細長い多層ペプチドナノ構造体とを含み、前記ナノ構造体のそれぞれは、電気的に帯電されており、かつ複数のペプチドを有し、前記ナノ構造体は、前記基体の1平方ミクロンあたり少なくとも1個のペプチドナノ構造体の表面密度で前記基体表面に略垂直に配置されており、前記ペプチドのそれぞれは、2個〜6個のアミノ酸残基を含み、前記デバイスは、電界効果トランジスター、導電層、センサー、医療用リード線、刺激用電極、熱エネルギーを移動するためのデバイス、及び分析物捕集デバイスからなる群から選択される、デバイス。
- 前記複数のペプチドにおけるそれぞれのペプチドが、少なくとも1つの芳香族アミノ酸残基を含む、請求項1に記載のデバイス。
- 前記複数のペプチドにおける少なくとも1つのペプチドが、エンドキャッピング修飾ペプチドである、請求項1または2に記載のデバイス。
- 前記複数のペプチドにおける少なくとも1つのペプチドが、芳香族アミノ酸残基から本質的になる、請求項2に記載のデバイス。
- 前記複数のペプチドにおける少なくとも1つのペプチドが、ジペプチドである、請求項1に記載のデバイス。
- 前記複数のペプチドにおけるそれぞれのペプチドが、フェニルアラニン−フェニルアラニンジペプチドである、請求項5に記載のデバイス。
- 前記ペプチドナノ構造体の少なくとも1つが、ナノ粒子の少なくとも1つの層によって被覆され、前記ナノ粒子が磁性ナノ粒子または電気的に帯電されたナノ粒子である、請求項1〜6のいずれかに記載のデバイス。
- 少なくとも1つのペプチドナノ構造体が、そのペプチドナノ構造体に結合した官能基を含む、請求項1〜7のいずれかに記載のデバイス。
- 前記複数のペプチド中の少なくとも1つのペプチドが、ホモジペプチドである、請求項1〜5、7及び8のいずれかに記載のデバイス。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87249906P | 2006-12-04 | 2006-12-04 | |
US60/872,499 | 2006-12-04 | ||
PCT/IL2007/001495 WO2008068752A2 (en) | 2006-12-04 | 2007-12-04 | Formation of organic nanostructure array |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2010512015A JP2010512015A (ja) | 2010-04-15 |
JP2010512015A5 JP2010512015A5 (ja) | 2011-01-27 |
JP5323717B2 true JP5323717B2 (ja) | 2013-10-23 |
Family
ID=39492719
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009539870A Expired - Fee Related JP5323717B2 (ja) | 2006-12-04 | 2007-12-04 | 有機ナノ構造体アレイの形成 |
Country Status (5)
Country | Link |
---|---|
US (2) | US20120021954A1 (ja) |
EP (1) | EP2089418B1 (ja) |
JP (1) | JP5323717B2 (ja) |
CN (1) | CN101652382B (ja) |
WO (1) | WO2008068752A2 (ja) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5323717B2 (ja) | 2006-12-04 | 2013-10-23 | ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド | 有機ナノ構造体アレイの形成 |
KR101071325B1 (ko) * | 2008-08-05 | 2011-10-07 | 재단법인서울대학교산학협력재단 | 정렬된 나노구조물을 구비한 회로 기판 및 그 제조 방법 |
US8178787B2 (en) * | 2008-08-26 | 2012-05-15 | Snu R&Db Foundation | Circuit board including aligned nanostructures |
ES2517919T3 (es) | 2008-09-02 | 2014-11-04 | The Governing Council Of The University Of Toronto | Microelectrodos nanoestructurados y dispositivos de biodetección que los incorporan |
GB0906851D0 (en) * | 2009-04-21 | 2009-06-03 | Cambridge Entpr Ltd | Materials based on filamentous peptide or protein based structures |
US8253536B2 (en) * | 2009-04-22 | 2012-08-28 | Simon Fraser University | Security document with electroactive polymer power source and nano-optical display |
US8632873B2 (en) | 2009-08-17 | 2014-01-21 | Ramot At Tel-Aviv University Ltd. | Aligned nanoarray and method for fabricating the same |
WO2011060229A1 (en) * | 2009-11-12 | 2011-05-19 | The Regents Of The University Of California | Porous thin films |
US9305766B2 (en) * | 2009-12-22 | 2016-04-05 | Qunano Ab | Method for manufacturing a nanowire structure |
MY178405A (en) * | 2009-12-25 | 2020-10-12 | Suntory Holdings Ltd | Learning motivation improvers |
JP5989668B2 (ja) | 2011-01-11 | 2016-09-07 | ザ ガバニング カウンシル オブ ザ ユニバーシティ オブ トロント | タンパク質検出方法 |
CA2912161A1 (en) | 2013-07-18 | 2015-01-22 | Halliburton Energy Services, Inc. | Joints comprising carbon nanoforests |
FR3014596B1 (fr) * | 2013-12-11 | 2017-04-21 | Commissariat Energie Atomique | Film thermiquement conducteur permettant d'evacuer la chaleur preferentiellement dans une ou plusieurs directions de son plan |
EP3820810A4 (en) * | 2018-07-12 | 2022-06-08 | Ramot at Tel-Aviv University Ltd. | SELF-ASSEMBLED NANOSTRUCTURES, AND COMPOSITE MATERIALS THAT CAN BE USED FOR DENTAL APPLICATIONS CONTAINING SUCH NANOSTRUCTURES |
CN110231317B (zh) * | 2019-05-07 | 2020-02-21 | 皖西学院 | 基于硅基表面固定CdS纳米晶荧光探针、制备方法及其对Cu2+的检测 |
TWI746974B (zh) | 2019-05-09 | 2021-11-21 | 國立清華大學 | 熱電奈米感測器及其製造方法與應用方法 |
CN111217319B (zh) * | 2019-11-20 | 2023-04-11 | 西南交通大学 | 一种一维ZnO纳米异质结阵列的制备方法 |
CN111293013B (zh) * | 2020-03-27 | 2021-06-04 | 中山大学 | 一种场发射冷阴极结构及其制造方法 |
KR20220122880A (ko) * | 2021-02-26 | 2022-09-05 | 삼성전자주식회사 | 연신 센서 및 그 제조 방법과 웨어러블 기기 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6953656B2 (en) * | 2000-07-14 | 2005-10-11 | Massachusetts Institute Of Technology | Direct, externally imposed control of polypeptides |
KR100837393B1 (ko) | 2002-01-22 | 2008-06-12 | 삼성에스디아이 주식회사 | 탄소와 친화도가 높은 금속을 전극으로 구비하는 전자소자 |
AU2003286404A1 (en) * | 2002-12-09 | 2004-06-30 | Ramot At Tel Aviv University Ltd. | Peptide nanostructures, methods for their preparation and use |
ATE426575T1 (de) * | 2003-01-07 | 2009-04-15 | Univ Ramot | Peptidenanostrukturen die fremdmaterial enthalten,und verfahren zur herstellung derselben |
JP2005014431A (ja) * | 2003-06-26 | 2005-01-20 | Ricoh Co Ltd | 画像形成装置 |
CN101300026A (zh) * | 2003-10-15 | 2008-11-05 | 得克萨斯系统大学评议会 | 电子、光、磁、半导体和生物技术应用中作为支架的多功能生物材料 |
JP2006027945A (ja) * | 2004-07-15 | 2006-02-02 | Nec Corp | カーボンナノチューブの選別方法 |
US8568637B2 (en) * | 2004-08-02 | 2013-10-29 | Ramot At Tel-Aviv University Ltd. | Method of forming a fiber made of peptide nanostructures |
WO2006027780A2 (en) * | 2004-09-08 | 2006-03-16 | Ramot At Tel Aviv University Ltd. | Peptide nanostructures containing end-capping modified peptides and methods of generating and using the same |
US7879212B2 (en) * | 2005-11-03 | 2011-02-01 | Ramot At Tel-Aviv University Ltd. | Peptide nanostructure-coated electrodes |
JP5323717B2 (ja) | 2006-12-04 | 2013-10-23 | ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド | 有機ナノ構造体アレイの形成 |
-
2007
- 2007-12-04 JP JP2009539870A patent/JP5323717B2/ja not_active Expired - Fee Related
- 2007-12-04 EP EP07827468.5A patent/EP2089418B1/en not_active Not-in-force
- 2007-12-04 WO PCT/IL2007/001495 patent/WO2008068752A2/en active Application Filing
- 2007-12-04 CN CN200780050882.0A patent/CN101652382B/zh not_active Expired - Fee Related
- 2007-12-04 US US12/312,961 patent/US20120021954A1/en not_active Abandoned
-
2017
- 2017-04-10 US US15/482,867 patent/US10086354B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP2089418B1 (en) | 2016-11-09 |
CN101652382B (zh) | 2016-04-06 |
JP2010512015A (ja) | 2010-04-15 |
WO2008068752A2 (en) | 2008-06-12 |
US20120021954A1 (en) | 2012-01-26 |
WO2008068752A3 (en) | 2008-11-13 |
CN101652382A (zh) | 2010-02-17 |
US20170209845A1 (en) | 2017-07-27 |
US10086354B2 (en) | 2018-10-02 |
EP2089418A2 (en) | 2009-08-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5323717B2 (ja) | 有機ナノ構造体アレイの形成 | |
US8501697B2 (en) | Peptide nanostructures encapsulating a foreign material and method of manufacturing same | |
Wanekaya et al. | Nanowire‐based electrochemical biosensors | |
Griessl et al. | Self‐assembled two‐dimensional molecular host‐guest architectures from trimesic acid | |
AU2002343464B2 (en) | Biological control of nanoparticles | |
Chen et al. | An STM study of C60 adsorption on Si (100)-(2× 1) surfaces: from physisorption to chemisorption | |
US8796023B2 (en) | Peptide nanostructures containing end-capping modified peptides and methods of generating and using the same | |
US9493513B2 (en) | Polypeptides and their use | |
AU2002343464A1 (en) | Biological control of nanoparticles | |
WO2009126952A2 (en) | Large scale nanoelement assembly method for making nanoscale circuit interconnects and diodes | |
Schuster et al. | S-layer stabilized lipid membranes | |
US20110156109A1 (en) | Method and system for manipulating organic nanostructures | |
Calò et al. | Nanoscale device architectures derived from biological assemblies: The case of tobacco mosaic virus and (apo) ferritin | |
WO2012095811A1 (en) | Charge storage organic memory system | |
Chen et al. | Coverage-dependent Orientations of Dy@ C82 Molecules on Au (111) Surface | |
Slyngborg et al. | The Physical Properties and Self‐Assembly Potential of the RFFFR Peptide | |
US20220041651A1 (en) | Bioinspired highly thermo-sustainable packings with uses thereof | |
Ramirez et al. | Adsorption and self-assembly of a ferrocene D-and L-nonapeptide disulfide onto gold and mica substrates | |
Acar | Self-assembled peptide template directed synthesis of one-dimensional inorganic nanostructures and their applications | |
Thanjavur | Given Name Priyadharshini | |
ZIGANSHIN et al. | Thermal Stability, Sorption Properties and Morphology of Films of Dipeptide and Tripeptide Based on |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20101125 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20101125 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20121214 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20130314 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20130625 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20130717 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 5323717 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
LAPS | Cancellation because of no payment of annual fees |