JP5302200B2 - オキサゾリジノン誘導体および使用方法 - Google Patents

オキサゾリジノン誘導体および使用方法 Download PDF

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Publication number
JP5302200B2
JP5302200B2 JP2009533406A JP2009533406A JP5302200B2 JP 5302200 B2 JP5302200 B2 JP 5302200B2 JP 2009533406 A JP2009533406 A JP 2009533406A JP 2009533406 A JP2009533406 A JP 2009533406A JP 5302200 B2 JP5302200 B2 JP 5302200B2
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compound
formula
deuterium
linezolid
pharmaceutical composition
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Japanese (ja)
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JP2010507576A (ja
JP2010507576A5 (https=
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スコット ハーベソン
ロジャー タン
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コンサート ファーマシューティカルズ インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2009533406A 2006-10-23 2007-10-23 オキサゾリジノン誘導体および使用方法 Expired - Fee Related JP5302200B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US85389006P 2006-10-23 2006-10-23
US60/853,890 2006-10-23
US97463707P 2007-09-24 2007-09-24
US60/974,637 2007-09-24
PCT/US2007/022516 WO2008127300A2 (en) 2006-10-23 2007-10-23 Oxazolidinone derivatives and methods of use

Publications (3)

Publication Number Publication Date
JP2010507576A JP2010507576A (ja) 2010-03-11
JP2010507576A5 JP2010507576A5 (https=) 2010-12-09
JP5302200B2 true JP5302200B2 (ja) 2013-10-02

Family

ID=39864509

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009533406A Expired - Fee Related JP5302200B2 (ja) 2006-10-23 2007-10-23 オキサゾリジノン誘導体および使用方法

Country Status (5)

Country Link
US (1) US20080139563A1 (https=)
EP (1) EP2099299A4 (https=)
JP (1) JP5302200B2 (https=)
CA (1) CA2703011A1 (https=)
WO (1) WO2008127300A2 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8796267B2 (en) * 2006-10-23 2014-08-05 Concert Pharmaceuticals, Inc. Oxazolidinone derivatives and methods of use
WO2008070619A1 (en) * 2006-12-04 2008-06-12 Auspex Pharmaceuticals, Inc. Deuterated oxazolidinones and their use as antibiotics
US20090062283A1 (en) * 2007-08-29 2009-03-05 Protia, Llc Deuterium-enriched linezolid
WO2009154754A2 (en) * 2008-06-17 2009-12-23 Concert Pharmaceuticals, Inc. Synthesis of deuterated morpholine derivatives
SG10201406571YA (en) * 2009-10-13 2014-11-27 Melinta Therapeutics Inc Pharmaceutical compositions
CN104327004A (zh) * 2014-11-17 2015-02-04 重庆华邦制药有限公司 高纯度利奈唑胺氮氧化物的制备方法
EP3351553A4 (en) 2015-09-17 2019-06-19 Seoul National University R & DB Foundation BROKEN OR FOLDED HELIXFUL PEPTIDE OR PEPTIDE ANALOG WITH ANTIMICROBIAL ACTIVITY AGAINST GRAM NEGATIVE BACTERIA AND USE THEREOF
WO2017089892A1 (en) * 2015-11-25 2017-06-01 Astrazeneca Ab Deuterated isoxazole derivatives and their use as metabotropic glutamate receptor potentiators
US11608320B2 (en) 2020-02-02 2023-03-21 Kuwait University Oxazolidinone hydroxamic acid derivatives

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
US6221335B1 (en) * 1994-03-25 2001-04-24 Isotechnika, Inc. Method of using deuterated calcium channel blockers
PT1019385E (pt) * 1995-09-15 2004-06-30 Upjohn Co N-oxidos de aminoaril-oxazolidinona
US6255304B1 (en) * 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
US6884429B2 (en) * 1997-09-05 2005-04-26 Isotechnika International Inc. Medical devices incorporating deuterated rapamycin for controlled delivery thereof
KR20010015910A (ko) * 1998-01-23 2001-02-26 로렌스 티. 마이젠헬더 옥사졸리디논 조합 라이브러리, 조성물 및 제조 방법
US6440710B1 (en) * 1998-12-10 2002-08-27 The Scripps Research Institute Antibody-catalyzed deuteration, tritiation, dedeuteration or detritiation of carbonyl compounds
PT1104760E (pt) * 1999-12-03 2003-06-30 Pfizer Prod Inc Compostos de sulfamoil-heteroarilpirazole como agentes analgesicos e anti-inflamatorios
AR027261A1 (es) * 2000-02-02 2003-03-19 Upjohn Co Linezolid forma cristalina ii
US20030060465A1 (en) * 2000-12-19 2003-03-27 Jilani Jamal A. Prodrugs of non-steroidal anti-inflammatory and carboxylic acid containing compounds
TW200413273A (en) * 2002-11-15 2004-08-01 Wako Pure Chem Ind Ltd Heavy hydrogenation method of heterocyclic rings
AU2006274037B2 (en) * 2005-07-26 2012-04-26 Takeda Gmbh Isotopically substituted pantoprazole
CA2616383C (en) * 2005-07-29 2015-06-09 Concert Pharmaceuticals Inc. Novel benzo[d][1,3]-dioxol derivatives
CN101309917B (zh) * 2005-10-06 2013-09-11 奥斯拜客斯制药有限公司 具有增强治疗性质的胃h+，k+-atp酶氘代抑制剂
US7750168B2 (en) * 2006-02-10 2010-07-06 Sigma-Aldrich Co. Stabilized deuteroborane-tetrahydrofuran complex
WO2008030382A1 (en) * 2006-09-05 2008-03-13 Schering Corporation Pharmaceutical combinations for lipid management and in the treatment of atherosclerosis and hepatic steatosis
US8796267B2 (en) * 2006-10-23 2014-08-05 Concert Pharmaceuticals, Inc. Oxazolidinone derivatives and methods of use
WO2008070619A1 (en) * 2006-12-04 2008-06-12 Auspex Pharmaceuticals, Inc. Deuterated oxazolidinones and their use as antibiotics

Also Published As

Publication number Publication date
JP2010507576A (ja) 2010-03-11
CA2703011A1 (en) 2008-10-23
EP2099299A2 (en) 2009-09-16
US20080139563A1 (en) 2008-06-12
WO2008127300A2 (en) 2008-10-23
EP2099299A4 (en) 2011-11-30
WO2008127300A3 (en) 2008-12-11

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