JP5301449B2 - 有機アルセノキシド化合物およびその使用 - Google Patents

有機アルセノキシド化合物およびその使用 Download PDF

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JP5301449B2
JP5301449B2 JP2009533614A JP2009533614A JP5301449B2 JP 5301449 B2 JP5301449 B2 JP 5301449B2 JP 2009533614 A JP2009533614 A JP 2009533614A JP 2009533614 A JP2009533614 A JP 2009533614A JP 5301449 B2 JP5301449 B2 JP 5301449B2
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hydrogen
compound
methyl
alkyl
formula
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Japanese (ja)
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JP2010508245A (ja
JP2010508245A5 (cg-RX-API-DMAC7.html
Inventor
フィリップ ジョン ホッグ
ピエール ディルダ
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ニューサウス イノベイションズ ピーティーワイ リミテッド
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Priority claimed from AU2006906220A external-priority patent/AU2006906220A0/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/66—Arsenic compounds
    • C07F9/70—Organo-arsenic compounds
    • C07F9/74—Aromatic compounds
    • C07F9/76—Aromatic compounds containing hydroxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2009533614A 2006-11-01 2007-11-01 有機アルセノキシド化合物およびその使用 Active JP5301449B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2006906220A AU2006906220A0 (en) 2006-11-01 Arsenoxide compounds and use thereof
AU2006906220 2006-11-01
PCT/AU2007/001676 WO2008052279A1 (en) 2006-11-01 2007-11-01 Organo-arsenoxide compounds and use thereof

Publications (3)

Publication Number Publication Date
JP2010508245A JP2010508245A (ja) 2010-03-18
JP2010508245A5 JP2010508245A5 (cg-RX-API-DMAC7.html) 2010-12-16
JP5301449B2 true JP5301449B2 (ja) 2013-09-25

Family

ID=39343707

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009533614A Active JP5301449B2 (ja) 2006-11-01 2007-11-01 有機アルセノキシド化合物およびその使用

Country Status (8)

Country Link
US (2) US8268883B2 (cg-RX-API-DMAC7.html)
EP (1) EP2069371B1 (cg-RX-API-DMAC7.html)
JP (1) JP5301449B2 (cg-RX-API-DMAC7.html)
CN (1) CN101595115B (cg-RX-API-DMAC7.html)
AU (1) AU2007314076B2 (cg-RX-API-DMAC7.html)
CA (1) CA2668010C (cg-RX-API-DMAC7.html)
ES (1) ES2411094T3 (cg-RX-API-DMAC7.html)
WO (1) WO2008052279A1 (cg-RX-API-DMAC7.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2420229A1 (en) 2002-01-07 2012-02-22 Board Of Regents, University Of Texas System S-dimethylarsino-thiosuccinic acid s-dimethylarsino-2-thiobenzoic acid s-(dimethylarsino) glutathione as treatments for cancer
CN101863958B (zh) 2002-11-07 2012-07-18 新南创新私人有限公司 对线粒体通透性转换的诱导
WO2009043114A1 (en) * 2007-10-04 2009-04-09 Newsouth Innovations Pty Limited Arsenoxide compound and method of use
TWI539493B (zh) 2010-03-08 2016-06-21 黛納羅伊有限責任公司 用於摻雜具有分子單層之矽基材之方法及組合物
US8853438B2 (en) * 2012-11-05 2014-10-07 Dynaloy, Llc Formulations of solutions and processes for forming a substrate including an arsenic dopant
WO2016201481A1 (en) * 2015-06-15 2016-12-22 Newsouth Innovations Pty Limited Pharmaceutical combinations of organo-arsenoxide compounds and mtor inhibitors
CA3136647A1 (en) 2019-04-12 2020-10-15 Centenary Institute Of Cancer Medicine And Cell Biology Conjugates and their use as imaging agents

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2370092A (en) 1942-05-04 1945-02-20 Parke Davis & Co Organic amine derivatives and method of obtaining same
US2409291A (en) 1942-05-19 1946-10-15 Squibb & Sons Inc Chemotherapeutic sulfanilamide derivatives
US2465308A (en) 1946-11-27 1949-03-22 Hoffmann La Roche Arsenoso compounds and method of preparation
US2664432A (en) 1947-01-28 1953-12-29 Ernst A H Friedheim Heterocyclic metal and sulfur organic compounds
US2553515A (en) 1948-12-11 1951-05-15 Hoffmann La Roche N-(p-arsenoso-benzyl)-urea
US2951766A (en) 1957-07-15 1960-09-06 Le Roy A White Antiseptic plastic
BE786573A (fr) * 1971-07-20 1973-01-22 Hoechst Ag Medicament a base de composes arsenicaux organiques et de derives du benzimidazole
FR2640269B1 (fr) 1988-12-13 1991-03-15 Maes Ludo Composes organometalliques, leurs modes de preparation et compositions pharmaceutiques les contenant
US5270196A (en) 1989-10-20 1993-12-14 Bristol-Myers Squibb Company Arylsulfatase from streptomyces
FR2684382B1 (fr) 1991-12-02 1994-10-21 Rhone Merieux Medicaments et preparations pures de dichlorhydrate de melarsomine, leur procede d'obtention et produits intermediaires obtenus.
EP0981344A1 (en) 1997-05-14 2000-03-01 The University of New Mexico Inhibition of cell surface protein disulfide isomerase
AU751932B2 (en) 1997-10-15 2002-08-29 Polarx Biopharmaceuticals, Inc. Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds
CN1233476A (zh) 1998-04-24 1999-11-03 陆道培 治疗急性白血病的药物及其制备方法
AU769756B2 (en) 1998-11-03 2004-02-05 Mitokor Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor
US6191123B1 (en) 1999-03-19 2001-02-20 Parker Hughes Institute Organic-arsenic compounds
CA2375542A1 (en) 1999-06-22 2000-12-28 James A. Dykens Compositions and methods for assaying subcellular conditions and processes energy transfer
AUPQ296799A0 (en) 1999-09-20 1999-10-14 Unisearch Limited A cell-membrane impermeable trivalent organoarsenical derivative and use thereof
AUPR379801A0 (en) 2001-03-19 2001-04-12 Unisearch Limited Use of a substantially cell membrane impermeable compound for treating arthritis
AUPR598901A0 (en) * 2001-06-28 2001-07-19 Unisearch Limited Inhibition of angiogenesis by targeting protein tyrosine phosphatases
AUPR874601A0 (en) 2001-11-08 2001-11-29 Unisearch Limited Selective targeting of apoptotic cells
EP2420229A1 (en) * 2002-01-07 2012-02-22 Board Of Regents, University Of Texas System S-dimethylarsino-thiosuccinic acid s-dimethylarsino-2-thiobenzoic acid s-(dimethylarsino) glutathione as treatments for cancer
AU2002952526A0 (en) * 2002-11-07 2002-11-21 Unisearch Limited Induction of the mitochondrial permeability transition
CN101863958B (zh) 2002-11-07 2012-07-18 新南创新私人有限公司 对线粒体通透性转换的诱导
WO2009043114A1 (en) 2007-10-04 2009-04-09 Newsouth Innovations Pty Limited Arsenoxide compound and method of use

Also Published As

Publication number Publication date
US8268883B2 (en) 2012-09-18
JP2010508245A (ja) 2010-03-18
WO2008052279A1 (en) 2008-05-08
EP2069371A4 (en) 2010-02-10
US20100041749A1 (en) 2010-02-18
ES2411094T3 (es) 2013-07-04
EP2069371A1 (en) 2009-06-17
US9765101B2 (en) 2017-09-19
CN101595115A (zh) 2009-12-02
EP2069371B1 (en) 2013-03-13
US20130041027A1 (en) 2013-02-14
CA2668010C (en) 2015-03-24
AU2007314076A1 (en) 2008-05-08
AU2007314076B2 (en) 2012-07-19
CN101595115B (zh) 2012-07-18
CA2668010A1 (en) 2008-05-08

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