JP5301442B2 - External sheet and external sheet set - Google Patents

Description

  The present invention relates to an external sheet agent and an external sheet agent set, and more particularly to an external sheet agent and an external sheet agent set that generate hydrogen efficiently at low cost and continuously.

  In recent years, people who are suffering from rheumatoid arthralgia, back pain, hay fever, general fatigue, cold, etc. due to aging or increased stress due to workplace automation, including diversification of nature and living environment, It is increasing regardless of.

  Therefore, various measures have been taken including medical institutions, and one of them is a method using negative ions. For example, Patent Document 1 discloses that a negative adhesive is generated in the adhesive layer of an outer skin adhesive type patch in which a hydrophilic adhesive layer containing moisture is laminated on one side of a film-like or sheet-like support. An external patch containing a body is disclosed. Patent Document 2 discloses a negative ion generator containing a negative ion generator and a hygroscopic body as essential components.

On the other hand, the hydrogen occluded in the hydrogen occlusion porous material is quickly taken into the cells that make up the human body when taken directly into the body as edible hydrogen, and produces ATP via the citric acid circuit in the mitochondria. In addition to promoting hydrogen, hydrogen is released and active oxygen such as hydroxy radicals and superoxide radicals are eliminated as water. It is known that this causes a physiological response to activate the cells. In Patent Document 3, coral calcium powder is kneaded by adding water to a mass ratio of 55% and a flour mass ratio of 45%. After forming into a plate shape and drying, the dried molded body is oxidized and fired at 700 ° C. for 4 hours, and then reduced and fired at 650 ° C. for 4 hours in a reduction furnace in an N 2 gas / H 2 gas atmosphere. A method for producing edible hydrogen as a powder is disclosed. Patent Document 4 discloses an antioxidant composition obtained by mixing brown rice powder and calcined calcium calcium powder adsorbed with hydrogen.
JP 2003-171265 A JP 2003-169852 A JP 2005-245265 A JP 2007-217351 A

  However, although the method described in Patent Document 1 can reduce the influence due to the change in the amount of moisture in the air, since the negative ion generator is contained in the adhesive layer containing moisture, it has already been stored. Negative ions are generated, and sufficient negative ions cannot be generated during use, and it has been desired to generate negative ions and the like efficiently and continuously. In addition, although the method described in Patent Document 2 can reduce the influence due to the change in the amount of moisture in the air, it requires a hygroscopic body, which is costly and labor intensive, and negative ions and the like can be produced at a lower cost. There has been a demand for a sheet for external use that is generated efficiently and continuously.

  In addition, since the methods described in Patent Documents 3 and 4 are mainly related to foods, there is room for improvement with regard to providing hydrogen to the skin efficiently and continuously as an external preparation.

  SUMMARY OF THE INVENTION Accordingly, an object of the present invention is to solve the above-described problems of the prior art and provide an external sheet and an external sheet set that generate hydrogen efficiently and continuously at a lower cost.

  As a result of intensive studies to solve the above problems, the present inventors have found that the object can be achieved by not allowing the sheet having the pressure-sensitive adhesive and the hydrogen storage porous material to coexist during storage, The present invention has been completed.

That is, the external sheet of the present invention is characterized in that a hydrogen storage porous material made of hydrogen storage and calcined coral calcium is disposed on a sheet having an adhesive on one side.

  Further, the external sheet of the present invention is preferably formed by adding an organic acid to the hydrogen storage porous material, and the organic acid is citric acid, tartaric acid, lactic acid, glycolic acid, malic acid, dilute hydrochloric acid, acetic acid, It is preferably at least one selected from the group consisting of oxalic acid and D-glucuronic acid.

  Furthermore, in the external sheet of the present invention, it is preferable that the hydrogen storage porous material is in the form of a paste, a powder or a granule.

  Further, the external sheet of the present invention preferably has an aluminum layer on a sheet having an adhesive on one side, and a hydrogen storage porous material is disposed on the aluminum layer. It is preferable to have an aluminum layer on the lower side of a sheet having an adhesive on one side.

External sheet agent set of the present invention, which is characterized in that it consists a sheet having an adhesive on one side, a paste, a hydrogen absorbing porous substance composed of a hydrogen storage fired coral calcium in powder or granular It is.

  ADVANTAGE OF THE INVENTION According to this invention, the external sheet agent and external sheet agent set which generate | occur | produce hydrogen continuously at lower cost efficiently can be provided.

It is a perspective view which shows one Embodiment of the sheet | seat in this invention. It is a perspective view which shows one Embodiment of the hydrogen storage porous substance tablet in this invention. It is sectional drawing which shows one Embodiment of the hydrogen storage porous substance tablet in this invention. It is a perspective view which shows other one Embodiment of the hydrogen storage porous substance tablet in this invention. It is sectional drawing which shows other one Embodiment of the hydrogen storage porous substance tablet in this invention. It is a perspective view which shows other embodiment of the sheet | seat in this invention. It is a perspective view which shows embodiment of the sheet | seat which has an aluminum layer in this invention. It is a perspective view which shows other embodiment of the sheet | seat which has an aluminum layer in this invention. It is a figure which shows the usage method of a sheet | seat for external use. It is a figure which shows the usage method of another sheet | seat for external use.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Tablet 1a Tablet diameter 1b Tablet thickness 2 Tablet recessed part 2a Recessed diameter 2b Recessed depth 3 Adhesive-containing sheet 4 Hydrogen-absorbing porous material 5 in paste, powder or granule 5 Organic acid 6,7 External sheet 8,9 Aluminum layer

  The external sheet of the present invention is obtained by disposing a hydrogen storage porous material on a sheet having an adhesive on one side. The arrangement method is not limited as long as it is disposed on the sheet having the adhesive immediately before the hydrogen-occlusion porous material is attached to the skin, and a tablet or the like is applied by applying a paste or the like. Also good. Since the hydrogen storage porous material is placed before being attached to the skin, a large amount of hydrogen is immediately generated after placement at a lower cost, and hydrogen is generated until the organic acid is placed. Therefore, hydrogen can be generated for a long time. Therefore, by applying the external sheet of the present invention to pain, inflammation sites, etc., hydrogen can permeate into cells oxidized by active oxygen over time, and inflammation can be suppressed by its reducing power. It can be expected to have an anti-inflammatory and analgesic action that is not immediately available.

  Further, the external sheet of the present invention can be used not only for humans but also for animals such as dogs, cats, horses and cows. By pasting the external sheet of the present invention on pain, inflammation sites, etc. of such animals, hydrogen can penetrate into cells oxidized by active oxygen over time, and inflammation can be suppressed by its reducing power, Expected to have an immediate anti-inflammatory / analgesic action that has never been seen before. In particular, it can be suitably used for the treatment of legs such as racehorses.

  The hydrogen storage porous material used in the present invention is not limited as long as it is porous and can store hydrogen, and the desired effect can be obtained. For example, hydrogen storage calcined coral calcium, hydrogen storage zeolite, hydrogen storage It is preferably at least one selected from the group consisting of charcoal, hydrogen storage activated carbon, hydrogen storage barleystone, hydrogen storage tourmaline and hydrogen storage rare earth ore, more preferably hydrogen storage calcined coral calcium or hydrogen storage zeolite. .

  As a method for producing such a hydrogen storage porous material, for example, there is a production method described in JP-A-2005-245265, and specifically, the porous material is oxidized and fired in an oxidation firing furnace at 700 ° C. for 4 hours. After the temperature is returned to normal temperature, it is manufactured by two-stage firing such as oxidation firing and reduction firing, such as reduction firing at 650 ° C. for 4 hours in an atmosphere of N 2 gas: H 2 gas (90 vol.%: 10 vol.%). can do.

  In addition, coral calcium used as a porous material is calcium contained in sandy fossil corals deposited on the sea floor, and fossil corals are rich in minerals such as magnesium and potassium in addition to calcium. Moreover, it is a natural material that is highly water-soluble and easily ionized, and therefore has high absorption efficiency into the human body. Such coral calcium is not particularly limited as long as the desired effect of the present invention can be obtained.

  Furthermore, zeolite used as a porous material is an aluminosilicate with fine pores in the crystal, and natural or synthetic products produced from crystal cavities formed in volcanic rocks and lava in hot spring areas are used. be able to. Zeolite has a bonded structure formed by silicon and aluminum mediating oxygen, and can store hydrogen in the pores by molecular adsorption.

  Furthermore, charcoal, activated carbon, barley stone, tourmaline and rare earth ore used as porous materials can use charcoal, activated carbon, barley stone, tourmaline and rare earth ore available on the market and occlude hydrogen. Thus, a hydrogen storage porous material can be obtained.

  Further, in the present invention, the dosage form of the hydrogen storage porous material is not particularly limited, and may take the form of a liquid, sol or gel fluid (for example, paste), powder, granule, tablet and the like. . In addition, other components may be added to the hydrogen occlusion porous material so long as the effects of the present invention are not impaired. For example, brown rice flour, soy milk, okara soy bean juice, etc. Etc.

  Furthermore, in the present invention, it is preferable to add an organic acid to the hydrogen storage porous material. Here, the addition includes means such as dropping. As a result, the organic acid dissolves the hydrogen-absorbing porous material immediately before being applied to the skin, so that a large amount of hydrogen is generated immediately and very little hydrogen is generated until the organic acid is added. Hydrogen can be generated for a long time. The organic acid is not limited as long as it reacts with the hydrogen-absorbing porous material to generate hydrogen, but preferably citric acid, tartaric acid, lactic acid, glycolic acid, malic acid, dilute hydrochloric acid (for example, hydrochloric acid) Somonade), acetic acid (for example, cereal vinegar), oxalic acid and D-glucuronic acid, and more preferably citric acid that is easily available. Moreover, this organic acid needs to be a solution, Preferably it is 10-30 mass% citric acid aqueous solution, More preferably, it is 20 mass% citric acid aqueous solution. Further, the aqueous solution may contain other components as long as the effects of the present invention are not impaired.

  Furthermore, in the present invention, the blending ratio of the hydrogen storage porous material and the organic acid is preferably 5: 1 to 5: 3, more preferably 5: 1 to 5: 2. It is preferable that the mixing ratio of the hydrogen storage porous material and the organic acid is 5: 1 to 5: 3 because a more appropriate amount of hydrogen can be generated for a long period of time.

  FIG. 1 is a perspective view showing an embodiment of a sheet according to the present invention. As shown in FIG. 1, it is preferable that the external sheet | seat agent of this invention is the tablet 1 in which the hydrogen storage porous substance provided the recessed part 2 which receives the said organic acid. Thus, the organic acid is received by the concave portion 2 of the tablet 1, so that the organic acid can dissolve the hydrogen-absorbing porous material immediately before being attached to the skin, and a large amount of hydrogen can be generated immediately and immediately. Until the addition, hydrogen generation is extremely small, so that hydrogen can be generated for a long time. The number and position of the recesses 2 in the tablet 1 are not limited, but preferably one recess 2 for receiving the organic acid is provided on one side of the tablet.

  FIG. 2 is a perspective view showing an embodiment of the hydrogen storage porous material tablet according to the present invention, and FIG. 3 is a cross-sectional view showing an embodiment of the hydrogen storage porous material tablet according to the present invention. FIG. 4 is a perspective view showing another embodiment of the hydrogen storage porous material tablet according to the present invention, and FIG. 5 is a cross section showing another embodiment of the hydrogen storage porous material tablet according to the present invention. FIG. Examples of the shape of the tablet 1 are tableting types that are usually used in pharmaceuticals and health foods, and examples thereof include a disc shape, a lens shape, a button shape, and a trapezoid shape, and preferably a lens shape. (FIGS. 2 and 3) or button shape (FIGS. 4 and 5). In addition, the size of the tablet 1 is not particularly limited, but the diameter 1a is preferably 4 to 30 mm, and more preferably 8 to 15 mm. Furthermore, the thickness 1b of the tablet 1 is appropriately selected according to the diameter 1a of the tablet 1, and is preferably 2 to 10 mm, and more preferably 3 to 5 mm. Furthermore, the mass of the tablet 1 is preferably 100 to 1000 mg, and more preferably 200 to 500 mg.

  The size 2a, 2b of the recess 2 in the tablet 1 is not limited as long as it can receive and store the added organic acid, but the ratio of the tablet 1 to the diameter 1a and the thickness 1b is preferably 20 It is -80%, More preferably, it is 40-60%. As such a tablet 1, for example, a calcium processed food (trade name: hydrogen every day, manufactured by Sante Corporation) can be used with a recess 2 provided.

  FIG. 6 is a perspective view showing another embodiment of the seat in the present invention. As shown in FIG. 6, the external sheet of the present invention is obtained by applying a hydrogen-occlusion porous material 4 in the form of a paste, powder or granules onto a sheet 3 having an adhesive. However, it is preferable that it is paste-like. Since the hydrogen-occlusion porous material 4 is applied on the sheet immediately before being attached to the skin, the effects of the present invention can be obtained more easily.

  The hydrogen-occlusion porous material 4 is not limited as long as it is a paste, powder or granule containing the hydrogen-occlusion porous material, and contains other components as long as the effects of the present invention are not impaired. Also good. As this hydrogen storage porous material 4, for example, Sante Care (fucoidan paste, manufactured by Sante Global Co., Ltd.) can be used. Furthermore, in the present invention, the hydrogen storage porous material 4 includes 0.5 g to 5.0 g of hydrogen storage coral calcium (hydrogen bulk powder), 0.05 to 1.0 g of Igis seaweed powder, and citric acid powder. It is preferable to contain 0.1-2.0g. For example, in a commercially available S size adhesive bandage tape, 0.7 g of hydrogen storage coral calcium (raw hydrogen powder), 0.1 g of Igis seaweed powder and 0.2 g of citric acid powder can be used. 2.1g hydrogen occlusion coral calcium (hydrogen bulk powder), 0.3g Igis seaweed powder and 0.6g citric acid powder can be used. Moreover, with commercially available L size adhesive bandage tape, hydrogen occlusion coral calcium (hydrogen bulk powder) 4.2 g, Igis seaweed powder 0.6 g and citric acid powder 1.2 g can be used.

  Furthermore, in this invention, it is preferable to add kaolin (mud) and citric acid, and to use the base material as pH 4-5, for example, kaolin (mud) 1-10 g and citric acid 0.1-10 g It can be mixed well for a small plate, and the pH of the substrate can be 4-5.

  Furthermore, the method of application or the like is not particularly limited, and it can be applied by being dispersed in a substance that does not react with the hydrogen-occlusion porous material 4 in the form of paste, powder or granules. Similarly to the above, it is preferable to add an organic acid to the hydrogen storage porous material 4.

  FIG. 7 is a perspective view showing an embodiment of a sheet having an aluminum layer in the present invention. The external sheet of the present invention preferably has an aluminum layer 8 on a sheet 3 having an adhesive on one side, and a hydrogen storage porous material 4 is disposed on the aluminum layer 8. Since the aluminum layer 8 is on the surface having the adhesive, it is essential that the size of the aluminum layer 8 is smaller than the sheet 3 having the adhesive in consideration of the adhesiveness of the external sheet to the skin. FIG. 8 is a perspective view showing another embodiment of a sheet having an aluminum layer in the present invention. The external sheet of the present invention preferably has an aluminum layer 9 on the lower side of the sheet 3 having an adhesive on one side. Thereby, the leakage of the generated hydrogen to the outside can be prevented and the skin can be penetrated more efficiently. Therefore, by applying the external sheet of the present invention to pain, inflammation sites, etc., hydrogen can permeate into cells oxidized by active oxygen over time and inflammation can be further suppressed by its reducing power. It is possible to expect more immediate anti-inflammatory / analgesic action.

  The production method of the aluminum layers 8 and 9 in the present invention is not particularly limited as long as the aluminum layer can be produced. For example, the aluminum layers 8 and 9 are produced by aluminum vapor deposition, or a commercially available aluminum foil is bonded. Can be produced.

  The sheet that can be used in the present invention is not particularly limited as long as the desired effect of the present invention can be obtained. Preferably, the sheet is flexible and does not impair the feeling of use as a sheet for external use. A sheet formed of natural fibers and / or artificial fibers or a sheet formed of a polymer material can be appropriately selected and used. Furthermore, these materials may be used alone, or may be used as a sheet-like laminate in which at least two kinds selected from these materials are laminated.

  As a sheet | seat which consists of the said natural fiber and / or man-made fiber, paper, cloth, a towel, a blanket, knitting, a quilt, a nonwoven fabric, a woven fabric etc. can be mentioned, for example.

  Examples of the natural fibers include cotton, kapok, flax, ramie, cannabis, jute, shiro, manila hemp, sisal hemp, coyer fiber, etc. Examples include animal fibers such as camel hair, alpaca hair, mohair, and eyelashes.

  Examples of the artificial fibers include, for example, recycled fibers such as artificial silk, sufu, viscose, and bemberg, or polyamide fibers, polyester fibers, polyacrylic fibers, polyvinyl alcohol fibers, polyalkylene paraoxybenzoate fibers, Examples thereof include synthetic fibers such as polyurethane fibers, polyvinylidene chloride fibers, polyvinyl chloride fibers, polyacrylonitrile fibers, polyethylene fibers, polypropylene fibers, and polyclar, or semi-synthetic fibers such as acetate artificial fibers.

  Examples of the sheet made of the polymer material include polyethylene, polypropylene, polyamide, polyester, polyurethane, ethylene-vinyl acetate copolymer, polyvinyl chloride, polybutadiene, cellophane, polychloroprene, polyamino acid, and nitrile rubber. It is possible to use a sheet in which a synthetic resin such as butyl rubber or silicone rubber or a synthetic rubber or the like is thinly formed, and if necessary, a foam (breathable) or non-breathable (non-breathable) foamed foam. Can also be used. In this case, in the case of non-breathable (non-breathable) sheets or foams, breathability (moisture permeability) is imparted by perforating or stretching in a range that does not allow the generated hydrogen to diffuse to the outside. You can also

  Further, the size and shape of the sheet are not limited as long as the desired effect of the present invention can be obtained, and can be appropriately determined according to the site to be used. For example, 6.5 cm × 4.2 cm, 9 A rectangular shape of 0.0 cm × 6.0 cm, 13.0 cm × 7.2 cm, 18 cm × 24 cm, or a circular shape having a diameter of 22 mm can be used. Moreover, as thickness of this sheet | seat, Preferably it is 15-250 micrometers, More preferably, it is 30-100 micrometers.

  The pressure-sensitive adhesive that can be used in the present invention is not particularly limited as long as the desired effect of the present invention can be obtained without reacting with the above-described hydrogen storage porous material and the above-mentioned organic acid. It can be worn. Such an adhesive only needs to be provided on one side of the sheet, and may be provided on a part or the entire surface of the sheet, and is generally formed as an adhesive layer. Further, such an adhesive preferably has an adhesive strength that does not peel naturally during use, and preferably does not easily lose adhesiveness even when it comes into contact with moisture due to sweating, etc. Is a known lipophilic pressure-sensitive adhesive.

  Specific examples of the pressure-sensitive adhesive include a vinyl acetate pressure-sensitive adhesive, an acrylic pressure-sensitive adhesive, a polyvinyl alcohol-based pressure-sensitive adhesive, a polyvinyl acetal-based pressure-sensitive adhesive, a vinyl chloride-based pressure-sensitive adhesive, a polyamide-based pressure-sensitive adhesive, and a polyethylene-based pressure-sensitive adhesive. A thermoplastic adhesive such as an adhesive or a cellulose adhesive, or a rubber adhesive such as a nitrile rubber adhesive, a butyl rubber adhesive, or a chloroprene adhesive is preferably used. Is not particularly limited, but is preferably about 10 to 70 μm.

  To the external sheet of the present invention, a tackifier, an inorganic filler, an anti-aging agent, an antioxidant, an ultraviolet absorber, and a pigment are generally added to the pressure-sensitive adhesive within a range that does not impair the effects of the present invention. Etc. can be added.

  The external sheet set of the present invention is characterized by comprising a sheet having an adhesive on one side, the hydrogen storage porous material and the organic acid, and the hydrogen storage porous material contains an organic acid. It is preferable that it is a tablet provided with the recessed part to receive. Another external sheet set according to the present invention is characterized by comprising a sheet having an adhesive on one side and a hydrogen storage porous material in the form of a paste, powder or granules. By setting it as such an external sheet agent set, the external sheet agent of this invention can be obtained more easily.

  9 and 10 are diagrams showing how to use the external sheet. As shown in FIG. 9, the method for using the external sheet is to arrange the hydrogen storage porous material 1 on the sheet 3 having an adhesive on one side (FIG. 9A), and to store the hydrogen storage porous material 1. After adding the organic acid 5 (FIG. 9B), the external sheet 6 is adhered to the skin (FIG. 9C). In addition, as shown in FIG. 10, another method for using an external sheet is to apply a hydrogen storage porous material 4 in the form of a paste, powder or granules on a sheet 3 having an adhesive on one side. Later (FIG. 10A), the external sheet 7 is adhered to the skin (FIG. 10B). By using such a method of using the external sheet agents 6 and 7, the effect of the present invention by the hydrogen storage porous material and the organic acid can be realized, and it is oxidized by active oxygen by being attached to pain, an inflammatory site, etc. Hydrogen can permeate into the cells over time, and inflammation can be suppressed by its reducing power, and an unprecedented immediate anti-inflammatory and analgesic action can be expected.

Next, this invention is demonstrated based on an Example.
Example 1
(Production of hydrogen storage porous material)
Calcium processed food (trade name: hydrogen every day, manufactured by Sante Corporation) is used as a tablet, and a concave portion with a diameter of 4.5 mm and a depth of 3 mm is formed in the center of the tablet, and hydrogen storage porous Material tablet A was prepared.

(Preparation of organic acid)
1 g of citric acid was dissolved in 5 mL of purified water to prepare an organic acid aqueous solution A and stored in a 5 mL dropper bottle.

(Preparation of sheet A for external use)
The hydrogen-absorbing porous substance tablet A was adhered to the adhesive surface of a commercially available bandage tape having a diameter of 22 mm, and one drop (0.4 mL) of the organic acid aqueous solution A was dropped with a dropper to prepare an external sheet A.

The following evaluation was performed using the external sheet agent A.
(Rheumatoid arthralgia test)
For 9 volunteers (19 joints) having rheumatoid arthralgia, the sheet A for external use after dropping the organic acid aqueous solution A with a dropper was adhered to the site of rheumatoid arthritis. Pain was evaluated at a scale of 0 to 10 points, with 10 points representing the most painful state. Before the adhesion of the external sheet A, the score was 10 points, but after the adhesion of the external sheet A, all nine volunteers were markedly improved to 0 to 1 point. In addition, the analgesic effect was improved within 5 minutes in all cases and showed immediate effect.

(Back pain test)
For 5 volunteers with low back pain, the sheet A for external use after dropping the organic acid aqueous solution A with a dropper was adhered to the lower back. Pain was evaluated at a scale of 0 to 10 points, with 10 points representing the most painful state. Before the adhesion of the external sheet A, the score was 10 points, but after the adhesion of the external sheet A, the improvement was remarkably improved to 0 to 1 for all five volunteers.

(Hay fever test)
To 12 volunteers with hay fever, the sheet A for external use after dropping the organic acid aqueous solution A with a dropper was adhered to both sides of the stellate ganglion (acupoint). By sticking the sheet A for external use, nasal congestion and nasal discharge were improved for all 12 volunteers.

(Cold cold test)
For 3 volunteers who developed colds, the sheet A for external use after dripping the organic acid aqueous solution A with a dropper was adhered to the acupuncture points of the lungs. By adhering the sheet A for external use, all three volunteers were remarkably improved.

(Whole body fatigue test)
To one volunteer who felt general fatigue, the external sheet A after dropping the organic acid aqueous solution A with a dropper was adhered to the adrenal gland and thymus sites. By sticking the sheet A for external use, all the volunteers were remarkably improved.

(Wave measurement test)
A wave measuring device (zero search) was prepared, and the influence of the external sheet A on the skin was observed with the wave measuring device. As a result, the disappearance of the resonance reaction of adrenaline and noradrenaline was confirmed. Moreover, the increase in resonance of endorphins and serotonin was confirmed. Furthermore, a significant increase in ATP (adenosine triphosphate) resonance was observed.

  As is clear from Example 1, by using an external sheet A that efficiently and continuously generates hydrogen, symptoms such as rheumatoid arthralgia, low back pain, hay fever, general fatigue, and cold are alleviated. We were able to.

Example 2
(Preparation of external sheet B)
Sante Care (fucoidan paste, manufactured by Sante Global Co., Ltd.) was applied to the adhesive surface of a commercially available adhesive bandage tape having a diameter of 22 mm to prepare an external sheet agent B.

Example 3
(Preparation of external sheet C)
Hydrogen-absorbing coral calcium (hydrogen bulk powder) 700 mg, Igis seaweed powder 200 mg, and citric acid powder 100 mg were mixed, and this mixture was made into one bag. Six such sachets, 5 g of kaolin (mud) and 2 g of citric acid were placed in a small dish and mixed thoroughly to obtain a substrate (pH 4 to 5). The obtained base material was applied to the adhesive surface of a commercially available L-size adhesive bandage tape (18 cm × 24 cm) to produce an external sheet C.

(Horse evaluation test 1)
A thoroughbred with a right front leg contusion who felt painful enough to hate moving to training. The external sheet C was affixed to the right shin of the thoroughbred. On the first day after the application of the external sheet C, Thoroughbred was able to run lightly over the course 800-1000 m, indicating that the pain was relieved and had an analgesic effect. In addition, in the icing which is a conventional treatment, the blood circulation failure of the leg is not improved, and an unprecedented therapeutic effect is obtained by the external sheet C.

(Horse evaluation test 2)
A thoroughbred with a right forelimb fracture, and a thoroughbred immediately fixed with a cast because of severe pain in the fracture, was used. The cast was removed, and the external sheet C was applied directly to the thoroughbred fracture site and re-fixed with a cast. Several hours after the application of the external sheet C, the fracture pain was relieved and it was shown to have an analgesic effect. Pain could be completely removed by repeating the application of the external sheet C once a day for 3 days.

Example 4
(Preparation of sheet D for external use)
Hydrogen-absorbing coral calcium (hydrogen bulk powder) 700 mg, Igis seaweed powder 200 mg, and citric acid powder 100 mg were mixed, and this mixture was made into one bag. Six such sachets, 5 g of kaolin (mud) and 2 g of citric acid were placed in a small dish and mixed thoroughly to obtain a substrate (pH 4 to 5). An aluminum sheet was adhered to the adhesive surface of a commercially available L-size adhesive bandage tape (18 cm × 24 cm), and the base material obtained was applied to the adhesive surface of the adhesive bandage tape (18 cm × 24 cm) to prepare an external sheet D. .

Claims (6)

A sheet for external use, comprising a hydrogen storage porous material composed of hydrogen storage calcined coral calcium on a sheet having an adhesive on one side.   Claims obtained by adding one or more organic acids selected from the group consisting of citric acid, tartaric acid, lactic acid, glycolic acid, malic acid, dilute hydrochloric acid, acetic acid, oxalic acid and D-glucuronic acid to the hydrogen storage porous material. Item 1. An external sheet according to Item 1.   The external sheet according to claim 1 or 2, wherein the hydrogen-occlusion porous material is in the form of paste, powder or granules.   The sheet for external use according to claim 1, comprising an aluminum layer on a sheet having an adhesive on one side, and a hydrogen storage porous material disposed on the aluminum layer.   The external sheet | seat agent of Claim 1 which has an aluminum layer in the lower side of the sheet | seat which has an adhesive on the said single side | surface side. Sheets and, pasty, powdered or external sheet agent set characterized by comprising a hydrogen absorbing porous substance composed of a hydrogen storage fired coral calcium granular having an adhesive on one side.

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