JP2003171265A - Plaster for external use - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a plaster for external use having increased generation efficiency of minus ions developing extremely excellent action on the activation of metabolism, activation and reduction of blood and cell, promotion of blood flow, amelioration of shoulder stiffening, lumbago and cold constitution, recovery from fatigue, strengthening of the stomach and intestines, treatment of internal organ diseases, athlete's foot and atopic diseases, skin bleaching effect, stabilization of autonomic nerve (relaxation effect), recovery of immunity, conditioning of the body in weakly alkaline state, etc., and effective for imparting the body with stable minus ion effect. <P>SOLUTION: The plaster to be applied to the outer skin is produced by laminating a water-containing hydrophilic adhesive layer to a surface of a substrate film or sheet. The adhesive layer contains a minus ion generating material. <P>COPYRIGHT: (C)2003,JPO

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to activation of metabolism by negative ion effect, activation / reduction of blood and cells, promotion of blood circulation, stiff neck, low back pain, improvement of coldness, fatigue recovery, gastrointestinal enhancement, visceral diseases, Negative ion generator that realizes athlete's foot, atopy, skin beautifying effect, autonomic nerve stability (relaxing effect), immune recovery and weak alkalinization of the body is included in the hydrophilic adhesive layer containing water. The present invention relates to an external patch, and more particularly to an external patch that can increase the generation efficiency of negative ions and generate a stable amount of negative ions.

[0002]

2. Description of the Related Art Currently, many people have stiff shoulders, low back pain, cervical-shoulder-arm syndrome, habitual constipation, insomnia, headache, heavy headache, chest pain, indefinite pain in limbs, back pain, dizziness or drowsiness. I am suffering from a disease whose cause is unknown.

Recently, it has been considered that these diseases are caused by autonomic imbalance,
It is considered that one of the factors is that the number of companies introducing OA equipment has increased due to the recent IT revolution and the number of people handling computers has increased accordingly.

That is, stress caused by unfamiliar operation of OA equipment or work in the same posture for a long time disturbs the autonomic nervous function of the worker, resulting in autonomic imbalance, which causes the above-mentioned various It has been determined that disease will occur.

However, even if the person has the subjective symptom of these diseases and feels that the symptom is progressing,
Examinations at hospitals often show the same results as those of normal healthy persons, and most of the symptoms do not improve even after going to the hospital.

[0006] This is because autonomic imbalance is a so-called "syndrome", which is located between the disease and the symptom, and it is a major factor that it is difficult to grasp the cause. .

Here, the autonomic nerve is one of the human nervous systems that controls the functions of internal organs and the circulation of blood, that is, the functions of the stomach and intestines, sweating,
It mainly performs the expansion and contraction of blood vessels.

[0008] Therefore, autonomic imbalance is a condition in which autonomic nerves are altered by stress or the like, and the functions of internal organs and blood circulation fail, so that diseases such as stiff shoulders appear on the surface. is there.

By the way, recently, many research results have been reported that ions having a surface-active action called "minus ions" exert actions such as relaxing the mind and body, recovering fatigue, and lowering blood pressure. As an effective therapeutic means for diseases caused by autonomic imbalance, various products using a negative ion generator for artificially generating this negative ion and a negative ion generator such as tourmaline have been developed.

However, a negative ion generator for artificially generating negative ions is expensive, and
Since it is heavy and difficult to carry, its use in general households is restricted, and it is currently used only by some specialized institutions.

On the other hand, products using a negative ion generator such as tourmaline are popular because they are inexpensive and easy to handle, and are widely available on the market as products such as bracelets and necklaces.

By the way, this tourmaline is also called tourmaline, and even if it is finely crushed, it is spontaneously added to the positive and negative electrodes of the crystal.
There is a pole, and the weak current of this tourmaline flows into the water in the air or the water contained in the cells of the human body, which changes the water into ions with a surface-active action called negative ions. Stimulates the nervous system and enhances the functions of the hypothalamus (regulation of body temperature, hormone secretion, and autonomic nerves) to activate the immune system and natural healing functions, resulting in a cleaning effect, deodorizing effect, and sterilizing effect. Be done.

Tourmaline also has a function of absorbing heat emitted from the human body and irradiating far infrared rays. The irradiation of far infrared rays promotes blood circulation in the human body and promotes metabolism. To do.

The far-infrared irradiation function and negative ion effect expressed by such tourmaline are due to the activation of metabolism,
Blood / cell activation / reduction, blood circulation promotion, stiff shoulders, low back pain,
It is said to exert extremely excellent effects on improving coldness, recovering from fatigue, strengthening the gastrointestinal tract, visceral diseases, athlete's foot, atopy, beautiful skin effects, stabilizing autonomic nerves (relaxing effect), healing immunity or weakening the body. -ing

[0015]

However, even though it is often reported that tourmaline has a very excellent action as described above, it is actually found in products obtained by processing tourmaline into bracelets, necklaces and the like. In most cases, there are variations in the effects, and desired effects cannot be obtained.

This problem is not limited to the case where tourmaline is used as the negative ion generator, and the same result is obtained when negative ion generators such as rare earth ores and rare earth ores are used. is there.

Then, as a result of studying this problem by the present inventor, it was confirmed that the generation efficiency of negative ions in the negative ion generator is greatly affected by the amount of moisture (humidity) in the air.

That is, as described above, the negative ions are the water in the air and the water contained in the cells of the human body changed into ions having a surface-active action by the negative ion generator. The generation efficiency of negative ions varies depending on the amount of water around the ion generator.

Therefore, the present inventor has made extensive studies to solve the above technical problems and improve the generation efficiency of negative ions in the negative ion generator. As a result, the hydrophilicity containing water on one side of the support. In the adhesive patch of the outer skin sticking type in which the pressure-sensitive adhesive layer is laminated, since this pressure-sensitive adhesive layer contains a negative ion generator, even if the amount of water in the air changes, a certain amount of negative ion is generated. It was found that it can be used as an external patch that can be generated to significantly improve the generation efficiency of negative ions.

That is, when the present inventors include a negative ion generator in the water-containing pressure-sensitive adhesive layer, a constant amount of water always exists in the vicinity of the negative ion generator, and a stable amount of negative ions is generated. We obtained the knowledge that it can be done.

The present invention has been completed on the basis of the above-mentioned findings, and it is an activation of metabolism, activation / reduction of blood and cells, blood circulation promotion, stiff shoulders, back pain, improvement of coldness, fatigue recovery, and gastrointestinal enhancement. , Visceral diseases, athlete's foot, atopy, beautiful skin effect, autonomic nerve stability (relaxation effect), recovery of immune system or weak alkalinity of the body. It is an object of the present invention to provide a skin-adhesive external patch that imparts an ionic effect.

[0022]

In order to achieve this object, in the patch for external use of the present invention, a hydrophilic pressure-sensitive adhesive layer containing water is laminated on one side of a film-like or sheet-like support. The adhesive patch of the outer skin sticking type is characterized in that the pressure-sensitive adhesive layer contains a negative ion generator.

That is, in the present invention, since the negative ion generator is contained in the water-containing pressure-sensitive adhesive layer, a certain amount of water always exists in the vicinity of the negative ion generator, and a stable amount of It is possible to generate negative ions. Hereinafter, the patch for external use of the present invention will be described in detail.

The film- or sheet-like support used in the present invention is not particularly limited, and a known cloth base material or the like can be appropriately selected and used. Woven fabric, felt, knitting or the like can be preferably used.

The material and type of the cloth base material are not particularly limited, and any of natural fibers and artificial fibers can be used.

Examples of the natural fiber include cotton, kapok, flax, ramie, cannabis, jute, spiro, manila hemp,
Examples include plant fibers such as sisal, Coyer fiber and the like, animal fibers such as domestic silk, silk, persimmon silk, wool (sheep), cashmere hair, camel hair, alpaca hair, mohair, rabbit hair and the like.

Examples of the artificial fibers include recycled fibers such as artificial silk thread, suf, viscose, and bemberg, polyamide fibers (such as nylon), polyester fibers (such as tetron, terylene, decron), and polyacrylic fibers. Fibers (Auron, Exlan, Bonnell, Casimirone, Kanecarone, etc.), Polyvinyl / alcohol fiber (Vinylon), Polyalkylene paraoxybenzoate fiber (benzoate), Polyurethane fiber (Polyurethane) [Spantex], Polyvinylidene chloride fiber (Vinylidene), polyvinyl chloride fiber (polyvinyl chloride), polyacrylonitrile fiber, polyethylene fiber (polyethylene), polypropylene fiber (polypropylene), polyclar, polypropylene fiber (pyrene), etc. , Or semi-synthetic fibers such as that manufactured the with natural substances and synthetic substances copolymerized with such as acetic artificial fibers.

In the present invention, in order to improve the mechanical strength of the patch for external use, or the feeling of use and the texture, at least a part or all of one side surface of the film or sheet made of the above-mentioned polymer material, It is preferable to use a laminate of films or sheets made of natural fibers and / or artificial fibers. Specifically, for example, a film or sheet made of a polymeric material such as polyurethane or rubber is provided on at least one side surface of a non-woven fabric or woven fabric. Examples thereof include those obtained by laminating a film or sheet made of natural fibers and / or artificial fibers.

In the topical patch of the present invention, it is not essential that the support has air permeability, but in particular, in order to suppress the occurrence of stuffiness, rash, itching, red spots, skin irritation and the like. It is preferable to impart air permeability.

In the present invention, since the pressure-sensitive adhesive layer containing water is used, it is preferable that the support be controlled by the moisture permeability.
It should be set in the range of 000 to 7,500 g / m ² · 24 hr.

This moisture permeability is 2,000 g / m ² · 24
If it is less than hr, adverse effects such as stuffiness, rash, itching, red spots and skin irritation are likely to occur, and safety and hygiene are deteriorated,
This is not preferable because not only the temperature of the pressure-sensitive adhesive layer rises and a sufficient cooling effect cannot be expected, but also the usability deteriorates. On the other hand, when it exceeds 7,500 g / m ² · 24 hr, the water content in the pressure-sensitive adhesive layer or The pressure-sensitive adhesive layer itself easily exudes to the outside of the support, which may stain clothes, or the moisture in the pressure-sensitive adhesive layer or other components described below may evaporate to hinder the medicinal effects, or It is not preferable because the negative ion effect and the compress effect can not be expected.

Therefore, from these viewpoints, it is most preferable to set the moisture permeability of the support in the range of 3,500 to 5,500 g / m ² · 24 hr.

By the way, the Lissie method (Lyssy method) is a method which complies with the industrial standards of various countries in the world.
According to IS Z 0208 and JIS K 7129, the temperature is set to 40 ° C. and the relative humidity difference is kept to 90% RH. Therefore, in this device, the lower chamber in the state of 100% relative humidity and the highly sensitive humidity sensor are used. The measurement sample is inserted on the boundary surface of the upper chamber where the
H (100% -90%), centered around this, measure the time (several seconds) required for the humidity to increase from +1 to -1, that is, from about 9% to about 11%. In this method, the transmittance is obtained by comparing with the result of the calibration performed under the same conditions using a standard sample whose transmittance is known in advance.

The thickness of the support varies greatly depending on the use and the type of the support and the pressure-sensitive adhesive layer, and is not particularly limited. Specifically, the basis weight is generally 3
It is preferably about 0 to 300 g / m ² .

When the thickness of the support is less than 30 g / m ^{2 in} basis weight, necessary mechanical strength cannot be obtained and it may be difficult to make the thickness uniform, which is preferable. Absent.

On the other hand, when the thickness of the support exceeds 300 g / m ² , the flexibility is lowered, the conformability to the body surface is significantly lowered, and the followability to the deformation and movement of the body surface is lowered. , It is not preferable because it feels stiff and the texture becomes bad.

Therefore, in particular, the thickness of the support is preferably in the range of 50 to 200 g / m ² , particularly preferably 70 to
It is desirable to set it in the range of 130 g / m ² , and it is desirable in this range since the required mechanical strength and flexibility can be obtained.

In the present invention, the pressure-sensitive adhesive layer is formed on one side of the support, but in the present invention, the negative ion generating efficiency of the negative ion generator contained in the pressure-sensitive adhesive layer is increased. Therefore, it is necessary that the pressure-sensitive adhesive layer contains water, and therefore, in the present invention, it is necessary to use a hydrophilic pressure-sensitive adhesive.

Specific examples include hydrophilic acrylic polymer adhesives such as polyacrylic acid adhesives, polyvinyl acetal adhesives, polyvinyl alcohol adhesives, cellulose adhesives, vinyl acetate adhesives and the like. To be

In the present invention, it is essential that the pressure-sensitive adhesive layer contains water. The amount of water is the kind and amount of the negative ion generator contained, or the pressure-sensitive adhesive described later. It is appropriately determined according to the thickness of the agent layer and the like, but is not particularly limited,
Generally, it is desirable that the amount is in the range of 20 to 90% by weight, preferably 40 to 85% by weight, particularly preferably 45 to 80% by weight, based on the entire pressure-sensitive adhesive layer.

If the water content is less than 20% by weight, the adhesive strength may be unstable and the adhesiveness may vary.
If it is too small, it becomes difficult to improve the desired negative ion generation efficiency. On the other hand, if it exceeds 90% by weight, the skin adhesion may be too large to obtain the desired skin adhesive force. Not preferable.

The thickness of the pressure-sensitive adhesive layer applied to the support varies depending on the application of the patch for external use and is not particularly limited, but is generally 250 to 4,000.
The range is preferably in the range of μm, particularly in the range of 1,000 to 3,000 μm, and when the thickness of the adhesive layer is less than 250 μm, the required water content and skin adhesiveness may not be obtained, while 4 If it exceeds 1,000 μm, not only is it bulky and the usability deteriorates, but also the economy deteriorates, which is not preferable.

In the present invention, the method and shape of the adhesive layer provided on a part of one side surface of the support are not particularly limited. Specifically, for example, the entire one side surface of the support is provided. The pressure-sensitive adhesive layer may be applied and laminated over the entire surface, or the pressure-sensitive adhesive layer may be applied by partially coating the pressure-sensitive adhesive layer on the entire one side surface of the support, such as a grid pattern, a stripe pattern, a dot pattern, or a sea-island pattern. It may be provided.

By the way, in the external patch of the present invention, it is desirable to cover the exposed surface of the pressure-sensitive adhesive layer with a releasable protective film when it is not used.

The external patch of the present invention is most characterized in that the water-containing pressure-sensitive adhesive layer contains a negative ion generator.

The negative ion generator refers to one that generates negative ions by ionizing action or one that generates negative ions by ionizing air by natural radiation, and negative ions are preferably generated by such action. Preferred examples of the negative ion generator include tourmaline, rare earth ore, dilute stone, amber, black carbon, garnet, coral stone, thoron and diatomaceous earth.

Of these, tourmaline is also called tourmaline, and even if it is finely crushed, there are + and − poles on both polarities of the crystal spontaneously, and the weak current of this tourmaline is caused by moisture in the air and cells of the human body. As a result of flowing into the contained water, the water changes into negative hydroxyl ions, which have surface-active effects. As a result, it stimulates the nervous system and functions of the hypothalamus (regulation of body temperature, hormone secretion, autonomic nerve). It has a function of enhancing the immune system and activating the function of natural healing, and at the same time, a cleaning effect, a deodorizing effect and a bactericidal effect are obtained.

Further, tourmaline continues to flow electrons semipermanently, and the permanent electrode of tourmaline has a current of several tens of microamperes at the same level as the biocurrent in the skin surface layer and the acupuncture points (good conducting points) which are electric conductors. This weak electric current acts as a current stimulus, and active hydrogen generated by its electrolysis removes active oxygen that adversely affects the human body, promotes the action on the hypothalamus, and It absorbs the heat emitted from the body and irradiates it with far-infrared rays to promote blood circulation in the human body and metabolism, and the negative ions released from tourmaline relax the mind and body, recover from fatigue and lower blood pressure. The effects such as are expressed.

On the other hand, the rare earth ore is an ore containing natural radioactive elements such as uranium and thorium, which emits a large amount of far infrared rays even at room temperature, and the radiant energy from the rare earth ore is water vapor and oxygen in the air. , Has the effect of changing nitrogen into negative ions by ionization, and the effect is almost the same as that of tourmaline.

Further, other negative ion generators have the same action as tourmaline or rare earth ores,
It produces negative ions.

As described above, the far-infrared effect and the negative ion effect of the negative ion generators such as tourmaline and rare earth ores normalize the autonomic nerves to activate metabolism, activate and reduce blood and cells, and circulate blood. It promotes stiff shoulders, low back pain, cervical-shoulder-arm syndrome, habitual constipation, insomnia, headache, heavy headache, chest pain, indefinite pain in limbs, back pain, dizziness or dullness of the legs, etc. The far-infrared effect and the negative ion effect have a very excellent synergistic effect.

In the present invention, the content of the negative ion generator in the pressure-sensitive adhesive layer is appropriately determined according to the type of the selected negative ion generator, the water content of the pressure-sensitive adhesive layer, and the like. Although not particularly limited, generally, a blending ratio of about 3 to 50% by weight is preferable, and further 5 to 30% by weight, based on the whole adhesive layer containing water. More preferable.

By the way, in the patch for external use of the present invention, various functional substances depending on the use are further added in the pressure-sensitive adhesive layer so that other effects other than the negative ion effect can be exhibited. For example, it is preferable to enclose at least one selected from percutaneously absorbable drugs, cosmetics, far-infrared radiators, bamboo vinegar or wood vinegar.

Here, the transdermal drug is not particularly limited, and known drugs can be appropriately selected and used. Specific examples include corticosteroids and anti-inflammatory analgesics. , Hypertension, anesthetic, hypnotic sedative,
A tranquilizer, an antihypertensive agent, an antibiotic, an antibacterial substance, a vitamin, an antiepileptic agent, a coronary vasodilator, an antihistamine, an antifungal substance and the like can be preferably used.

Further, sublimable crystals, peppermint oil, eucalyptus oil,
It is also one of the preferred embodiments to add lavender oil or the like as needed.

Further, boric acid water, physiological saline solution, bitumenous water, alcohol water, flaxseed oil, lime water, liver oil, olive oil, ribanol water, potassium permanganate solution, mentha water, which are generally used as poultices, Examples include creosote, capsaicin, mustard and the like.

Also, the cosmetics are not particularly limited, and cleanse, beautify and enhance the human body,
A general cosmetic that is intended to be used by a method such as rubbing, spraying or similar to the body in order to change the appearance or keep the skin or hair healthy, and has a mild effect on humans. Can be appropriately selected and used, but specifically, anti-inflammatory agents, astringents, cooling agents,
Drugs for preventing skin roughness such as vitamins, hormones, antihistamines, sebum inhibitors, drugs for acne such as keratin exfoliating and dissolving agents, animal and plant extracts such as aloe extract, ginseng extract, licorice extract, nutrients such as amino acids, etc. Can be mentioned.

Further, the far infrared radiator is not particularly limited as long as it has a function of suitably radiating a radio wave having a wavelength range near the far infrared region.
Of these, non-metal inorganic solids that emit far infrared rays (far infrared emitting ceramics) are preferable, and specifically, at least one selected from metal oxides, carbides, nitrides and carbonates is appropriately selected. Can be used.

Here, the "far infrared ray" is, to be exact, the lower limit of 0.76 to 0.83 μm at the long wavelength end of visible light.
The so-called "infrared rays" are electromagnetic waves with an upper limit of about 1 mm in the wavelength range. Of this "infrared rays", about 25 μm
The electromagnetic wave having the above wavelength range is referred to as "far infrared ray", but the "far infrared ray" in the present invention is not strictly limited so far, and refers to an electromagnetic wave including a wavelength in the vicinity of this wavelength range. Therefore, the "far-infrared radiation function" refers to a function / property that suitably radiates an electromagnetic wave including a wavelength in the vicinity of this wavelength range.

The metal in the far infrared emitting ceramic is not particularly limited, but for example, Al, Be, V, Fe, Y, Co, Cu, Ni, S.
i, Sn, Ti, Cr, Ce, Zr, Ca, Ta and N
Examples thereof include a metal or alloy selected from b and the like, which is formed into a film-less sheet, a powder or a grain.

The wood vinegar and bamboo vinegar are liquid products obtained by dry distillation of wood and bamboo, and have antibacterial and antiseptic effects.

[0062]

EXAMPLES The present invention will now be described in detail based on examples, but the present invention is not limited thereto.

Example Tourmaline powder 13.0 as a negative ion generator
In parts by weight, 9.0 parts by weight of glycerin, 4.0 parts by weight of sodium polyacrylate, 0.4 parts by weight of tartaric acid, 3.0 parts by weight of polyvinyl alcohol, 0.15 parts by weight of carboxyvinyl polymer, 0.1 part of 1-menthol. 2 parts by weight, 0.05 parts by weight of ethanol and 70.0 parts by weight of water are mixed, and further 0.1 part by weight of metasilicic acid / magnesium aluminate (trade name Neusilin manufactured by Fuji Chemical Industry Co., Ltd.) and aluminum hydroxide gel of 0.1. An adhesive layer prepared by adding 1 part by weight to one side of a polypropylene non-woven fabric having a basis weight of 100 g / m ² (water vapor transmission rate of 4,400 g / m ² · 24 hr, its size is 50 mm in length, 140 mm in width), Thickness about 2,800
The external application patch of the present invention was obtained by applying and aging so that the thickness became μm.

Comparative Example Styrene-isoprene-styrene block copolymer (S
A thickness of 150 g / mm of an adhesive prepared by mixing 13.0 parts by weight of tourmaline powder with 87.0 parts by weight of an IS) type adhesive.
m ² polypropylene non-woven fabric (moisture permeability 4,400g
/ M ² · 24 hr, its size is 50 mm in height and 140 in width
(mm) on one side and applied and aged so as to have a thickness of about 2,800 μm to obtain a patch according to a comparative example. That is,
The adhesive layer in the patch of this comparative example is a lipophilic adhesive and does not contain any water.

Twenty subjects who complain of stiff shoulders actually use the patches prepared in the above-mentioned Examples and Comparative Examples (leave them on the shoulders for 30 minutes), and a questionnaire survey is conducted on their feelings and effects. I went.

As a result, in the topical patch of the example, 18 of 20 test subjects answered that the stiff shoulder was remarkably reduced, and the remaining 2 test subjects answered that the stiff shoulder was reduced to some extent. , No one answered that it had no effect.

On the other hand, with respect to the poultice of the comparative example, 9 out of 20 test subjects answered that the stiff shoulder was alleviated to some extent, and the remaining 11 test subjects answered that there was almost no effect.

[0068]

[Effects] The present invention provides a skin-adhesive type patch comprising the above-mentioned constitution, wherein a hydrophilic adhesive layer containing water is laminated on one side of a film- or sheet-like support. By including a negative ion generator in the layer, a constant negative ion is generated even when the amount of water in the air changes, and the effect of significantly improving the negative ion generation efficiency is exhibited.

That is, in the present invention, by including the negative ion generator in the adhesive layer containing water, a certain amount of water always exists in the vicinity of the negative ion generator, and a stable amount of It produces the effect that negative ions can be generated.

Improving this negative ion generation efficiency,
The patch for external use of the present invention capable of generating a stable amount of negative ions is activated by metabolism, activation / reduction of blood and cells, blood circulation promotion, stiff shoulder, low back pain, improvement of coldness, fatigue recovery, gastrointestinal recovery. It exerts effects such as strengthening, visceral diseases, athlete's foot, atopy, beautiful skin effect, autonomic nerve stability (relaxation effect), recovery of immune system, weak alkalinity of body, and the like.

─────────────────────────────────────────────────── ─── Continuation of front page (51) Int.Cl. ⁷ Identification code FI theme code (reference) A61N 1/00 A61P 9/00 A61P 9/00 17/00 17/00 101 101 21/02 21/02 21/02 25 / 02 103 25/02 103 29/00 29/00 A61N 5/06 A // A61N 5/06 A61J 1/00 370C F term (reference) 4C053 AA10 4C076 AA74 BB31 DD27 DD38 EE06 EE09 FF68 4C082 PA01 PC01 PE08 PG03 PJ12 4C084 AA19 MA02 MA32 MA63 NA05 NA10 ZA241 ZA361 ZA891 ZA901 ZA941 ZB111 4C086 AA01 AA02 HA27 MA01 MA02 MA32 MA63 NA05 NA10 ZA24 ZA36 ZA89 ZA90 ZA94 ZB11

Claims (5)

[Claims] 1. An outer skin sticking type patch comprising a film-like or sheet-like support on one side of which a hydrophilic adhesive layer containing water is laminated, wherein the adhesive layer contains a negative ion generator. A patch for external use, which comprises: 2. The patch for external use according to claim 1, wherein the support is at least one selected from non-woven fabrics, woven fabrics, felts and knits. 3. The water content of the pressure-sensitive adhesive layer is in the range of 20 to 90% by weight based on the whole pressure-sensitive adhesive layer.
The external patch described in. 4. The negative ion generator is tourmaline,
Rare earth ore, kiyoseki, amber, black carbon,
4. At least one selected from garnet, coral stone, thoron or diatomaceous earth.
External patch according to the item. 5. The adhesive layer further comprises a transdermal drug,
The patch for external use according to claim 1, which contains at least one selected from cosmetics, far-infrared radiators, bamboo vinegar, and wood vinegar.