JP5274358B2 - Dispensing clean room unit - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a clean room unit for preparation of drugs in which an atmospheric air moderately changes in opening and closing a door. <P>SOLUTION: This clean room unit for preparation of drugs includes a work unit 30 equipped with a door 60, a clean bench 40 having a work table 41, pressure-adjustable air supply/exhaust systems (71, 72, etc.) exhausting the air from the clean bench 40 while supplying the clean air to a work room 34, and a control device 22 capable of executing heterogeneous drug preparation work by switching an atmospheric pressure of the work room 34 to a negative pressure or other pressures. In opening and closing the door 60, an air supply-side damper 18, an exhaust-side damper 15, a normally-closed damper 90 are automatically opened according to a manual operation of a damper operating member or by detecting opening/closing and operation of the door 60. <P>COPYRIGHT: (C)2011,JPO&amp;INPIT

Description

  The present invention integrates a work room equipped with a hinged door for entering and exiting a worker and a clean bench facing a work opening on the work table, and is suitable for dispensing work by one or a small number of people. The present invention relates to a clean room unit for dispensing that is independently installed inside a building.

[Known technology]
A conventional clean room unit improved so as to be suitable for dispensing work (see, for example, Patent Document 1) is provided with a work room isolated from the outside, a work opening, and the work opening facing the work room. Clean bench unit and installed independently inside the building, which can clean the air and adjust the pressure in the work room and the clean bench unit. An air conditioning system capable of generating an air shower, an air shower mode for generating an air shower in the work room when performing operation control of the air conditioning system, and a work that enables dispensing work by setting the work room to a positive pressure or a negative pressure. And air adjustment control means switchable between modes.

As described above, the air shower is generated in the work room to enable the dust removal of the worker, and the air shower is generated by the air adjustment system, thereby realizing a reduction in size and cost. In addition, by switching between positive pressure and negative pressure, when dispensing powerful drugs such as anti-cancer drugs, the work room is negative pressure to prevent external leakage of drugs, and when dispensing other drugs, the work room is positive pressure Thus, intrusion of contaminants can be prevented.
The work room is provided with an opening / closing door (opening door) for opening / closing an entrance / exit for an operator, and the clean bench unit is equipped with an opening / closing shutter for opening / closing the working opening, The system circulates air between the filter, the work room, and the clean bench unit while taking air from outside the unit.

[Undisclosed prior art]
However, in such a conventional so-called personal clean room unit for dispensing, even if the work room is downsized, the hinged door for entering and exiting the worker does not become small. The opening and closing of the worker entrance / exit is not a sliding door that is not suitable for sealing and has a wide movement range, but a hinged door suitable for sealing is adopted. Among them, a single door is adopted for miniaturization. This is because a sliding door with a certain size or larger is required to facilitate the entry and exit of the door. And when opening a hinged door, although it is a short time, until the sealing is canceled, the volume of the sealed space increases according to the degree of opening, and the internal atmospheric pressure decreases accordingly. For this reason, the ratio of the inflow amount at the time of opening to the volume of the work room, that is, the ratio of the amount of air flowing into the work room when the hinged door is opened and the volume of the work room is increased as the work room is reduced, Contamination of the work room and clean bench due to the inflowing air is also severe.

  To resume the work after opening the hinged door, the worker first enters the work room, closes the hinged door, and then cleans the work surface of the clean bench and the inner wall of the work room while supplying and exhausting air. After cleaning is completed, air supply / exhaust is continued and waits for the interior of the work room and clean bench to be sufficiently clean. Undesirable things such as waiting for more than an hour can occur if the length of the slag is long and the dirt is severe. Therefore, in order to reduce the influence of contamination due to the opening of the hinged door, the personal dispensing clean room unit has been improved as follows.

  That is, (see Patent Document 2), a work room that has an opening door for entering and exiting the worker and is isolated from the outside when the door is closed, and one end of the work table and the work opening on the work room faced the work room. A clean bench, a pressure-adjustable supply / exhaust system that exhausts air from the clean bench while supplying clean air to the work room, and a negative pressure is applied to the work room when controlling the operation of the supply / exhaust system. And a control device that enables a different dispensing operation to be performed by switching to another pressure. In the dispensing clean room unit that is independently installed in the building, the supply / exhaust system includes an intake side and an exhaust side. The side is completely separated, and only air taken in from outside is used to supply air to the work room, and all exhaust from the clean bench is taken out outdoors. Going on, things that have been developed.

WO2002005 / 119131 publication Japanese Patent Application No. 2008-269319

In the above dispensing clean room unit that completely separates the air supply system and the exhaust system in this way, the dispensing completion time is shortened based on the total volume ventilation in the outside air, so that the effect of contamination due to the opening of the hinged door is reduced and the dispensing is quickly performed. You can start working.
In addition, in the conventional dispensing clean room unit described above, an air shower is generated in the work room by the air conditioning system, thereby realizing downsizing and cost reduction without impairing the dust removal function of the worker. When dispensing powerful drugs such as anticancer drugs, the working room can be set to a negative pressure to prevent external leakage of the drugs.

As a result of trial manufacture of these clean room units for dispensing, it was also confirmed that the desired effects were exhibited.
However, there has been a demand for further improvements in practical use. Specifically, the smaller the unit, the more rapidly the air pressure changes in the work room due to opening and closing of the hinged door, which may create anxiety and discomfort for the worker. It is required to reduce the atmospheric pressure change.
Therefore, it is a technical problem to realize a clean room unit for dispensing with a gentle change in the working room pressure when opening and closing the hinged door.

  The dispensing clean room unit of the present invention (Solution 1) was created in order to solve such a problem, and has a hinged door for entering and exiting the worker, and is a work room that is isolated from the outside when it is closed. A clean bench with one end of a workbench and a work opening on the workbench facing the work room, and a pressure-adjustable air supply / exhaust air exhausted from the clean bench while supplying clean air to the work room And a control device that enables the dispensation work to be performed by switching the negative pressure of the working room to a negative pressure or another pressure when performing an operation control on the supply / exhaust system. In a dispensing clean room unit installed independently, the air pressure in the work room is switched by varying the opening of the air supply / exhaust path of the air supply / exhaust system according to the control of the control device. Is equipped in the supply and exhaust system damper to perform, the control device at the time of opening and closing of the hinged door, characterized in that adapted to fully open the damper.

  Moreover, the clean room unit for dispensing of the present invention (Solution means 2) includes a work room that has a hinged door for entering and exiting the worker and is isolated from the outside when the door is closed, one end of the work table, and a work opening on the work room. A clean bench facing the work room, a pressure-adjustable air supply / exhaust system that exhausts air from the clean bench while supplying clean air to the work room, and the operation control for the air supply / exhaust system. It is equipped with a control device that enables the dispensation work to be performed by switching the atmospheric pressure of the work room to negative pressure or other pressure, and it is normally closed in the clean room unit for dispensing that is installed independently inside the building However, when opened, the working unit is equipped with a damper that communicates the inside and outside of the working unit, and the damper is opened when the hinged door is opened and closed. Tsu, characterized in that is.

  The clean room unit for dispensing of the present invention (Solution means 3) is a clean room unit for dispensing of the above solution means 1 and 2 and is provided with a damper operating member for instructing an opening operation of the damper. The damper is opened when the hinged door is opened and closed by opening the damper longer than the time required for opening and closing the hinged door according to the operation of the operation member.

  Further, the dispensing clean room unit of the present invention (Solution means 4) is a dispensing clean room unit of the above solution means 1 and 2, provided with an open / close detector for detecting opening and closing of the hinged door, and the open / close detection. Based on the detection result of the detector, the damper is closed when the hinged door is closed, but the damper is opened when the hinged door is opened and opened, so that the damper is opened when the hinged door is opened and closed. It is characterized by becoming.

  The clean room unit for dispensing of the present invention is (Solution means 5), is a clean room unit for dispensing of the above solution means 4, and is provided with an operation detector for detecting the state of the opening / closing operation member of the hinged door, The damper is also opened when the opening / closing operation of the hinged door is detected based on the detection result of the operation detector.

In such a dispensing clean room unit of the present invention (solution means 1 and 2), the damper is opened when the hinged door is opened and closed, and the airtightness of the working room is temporarily broken. The atmospheric pressure change is relieved.
Therefore, according to the present invention, it is possible to realize a dispensing clean room unit in which the change in the working room pressure during opening and closing of the hinged door is gentle.

In the clean room unit for dispensing according to the present invention (solution 3), the relaxation of the change in atmospheric pressure is realized by manual operation.
Further, in the dispensing clean room unit of the present invention (solution 4), the reduction of atmospheric pressure is realized by automatic control according to the open / closed state of the hinged door.
Further, in the dispensing clean room unit of the present invention (Solution 5), the automatic control of the pressure change mitigation is started quickly at the preparation stage for opening the hinged door, so that the pressure change is more accurately mitigated. The

About Example 1 of the clean room unit for dispensing of this invention, (a) is a longitudinal cross-sectional view of the installation destination building which shows an installation state, (b) is a front view which shows the whole external appearance of a unit, (c) is an air flow path. FIG. 2 is a schematic diagram showing the internal structure of the air supply / exhaust system. FIG. About Example 2 of the clean room unit for dispensing of the present invention, (a) is an external view of the door periphery when the hinged door is closed, (b) is an interior view of the door periphery at that time, and (c) is the hinged door. External view of the door periphery when operating the opening / closing operation member to open, (d) is an interior view of the door periphery at that time, (e) is a cross-sectional view of the door periphery when the hinged door is opened, (F) is a block diagram showing a modified portion of the supply / exhaust system.

  With regard to the dispensing clean room unit of the present invention, several modes suitable for carrying out this will be described.

The dispensing clean room unit according to the first embodiment is a dispensing clean room unit of the above-described solving means, and the air supply / exhaust system is completely separated from an air supply side and an exhaust side, and air supply to the work room is performed. In this case, only air taken from outside is used, and all exhaust from the clean bench is sent to the outside.
In this case, the air supply side and the exhaust side of the air supply / exhaust system are completely separated, and the air taken in from the outside is sent to the work room, and all of it goes out through the clean bench. The air used for cleaning the room is not circulated and reused in the unit, but can be quickly replaced with the miniaturization of the unit.

  As described above, since the possibility that the used air remains in the circulation system is eliminated, the time spent waiting until the opening and closing of the hinged door and the cleaning by air supply and exhaust following the cleaning is completed is shortened. The supply / exhaust system needs to be strengthened because the supply / exhaust amount increases due to the complete separation between the air supply system that takes in outside air from the outside to the work room and the exhaust system that sucks out air from the work room and releases it to the outside. Since the unit is small, the increase in burden is small, and a circulation system is not required instead. Therefore, an undesirable increase in cost can be avoided and suppressed. Therefore, according to this embodiment, by shortening the waiting time for completion of cleaning based on total ventilation in the outside air, it is possible to realize a personal dispensing clean room unit that can start dispensing work quickly with less influence of contamination due to opening of the hinged door. can do.

The dispensing clean room unit according to the second embodiment is the dispensing clean room unit according to the first embodiment, and the supply / exhaust system sucks air from above and below the work table and carries it to the exhaust side. It is characterized by.
In this case, in addition to being supplied from the upper side of the work table, intake air to the outdoor exhaust from the unit by the exhaust system is supplied from the lower side of the work table. Therefore, dust and dust that have fallen down in the work room while waiting for completion of cleaning after opening and closing of the hinged door are efficiently removed. In addition, even when powder or the like enters the work room from the work table undesirably and falls down, the drug is quickly discharged from the work room through the work table. Even if it is a powerful medicine, the possibility and amount of exposure will be small, so the risk of dispensing workers is small.

The dispensing clean room unit according to the third embodiment is the dispensing clean room unit according to the first and second embodiments, and is provided with an open / close detector that detects opening / closing of the hinged door, and an indicator is provided inside the work room. The control device performs guidance display on opening / closing of the hinged door on the display based on a detection result of the opening / closing detector and a state of operation control on the air supply / exhaust system.
In this case, guidance display related to opening and closing of the hinged door is made on a display inside the work room. In addition, the guidance display is performed according to the open / closed state of the hinged door and the supply / exhaust state. For this reason, when the worker leaves the work room, the worker opens the hinged door at an appropriate time in consideration of the contents of the guidance display and the urgency of leaving the room. It is not preferable to lock the hinged door from the viewpoint of giving priority to emergency evacuation of dispensing workers, and at least it will not be locked from the outside. Leave the room when there is little contamination due to the opening of the hinged door.

The dispensing clean room unit according to the fourth embodiment is the dispensing clean room unit according to the first and second embodiments, provided with an operation detector for detecting the state of the opening / closing operation member of the hinged door, and opening / closing the working opening. A shutter that is provided on the clean bench, and the control device detects the opening operation of the hinged door during supply / exhaust based on a detection result of the operation detector and a state of operation control on the supply / exhaust system. The shutter is closed.
In this case, the dispensing work space on the work bench of the clean bench and the work room are partitioned by a shutter at an early stage in the preparation stage for opening the hinged door. As a result, even if the hinged door begins to open and the atmospheric pressure in the work room decreases, the dispensing work space and the work room are already partitioned at that time, so that pollutants such as powder flow into the work room from the dispensing work space. The occurrence of a desired situation can be avoided / reduced.

The dispensing clean room unit according to the fifth embodiment is the dispensing clean room unit according to the fourth embodiment, and is provided with an open / close detector that detects opening / closing of the hinged door, and the control device is configured to supply / exit the hinged door. After detecting the opening operation, when the opening operation of the hinged door is detected based on the detection result of the opening / closing detector, the supply / exhaust system is configured to strengthen the exhaust.
In this case, the exhaust is strengthened when the hinged door starts or opens. Thereby, it is possible to reduce the amount of contaminants that try to flow from the dispensing work space to the work room through the gap of the shutter, and to reduce the amount of the contaminant.

  The dispensing clean room unit of the sixth embodiment is the dispensing clean room unit of the first to fifth embodiments, and the operation detector is provided for the dispensing clean room unit of the fourth and fifth embodiments. Assuming that the open / close detector is provided for the clean room unit for dispensing of the third and fifth embodiments, the open / close detector for detecting the opening / closing of the hinged door in the first and second embodiments, On the premise that either one or both of the operation detectors for detecting the state of the opening / closing operation member of the hinged door are provided, the outer surface surrounding the work room is further below the door. An intake port is formed, and the supply / exhaust system selectively performs intake from the under-door intake port, and the control device Characterized in that it is the supply and exhaust system when detecting opening operation or the opening operation of the serial leaf door so as to perform suction from the door bottom inlet.

In this case, when trying to open or open the hinged door, air is sucked from the outer surface of the unit below the hinged door.
As a result, even if the powder is carried away from the work room by the air flow that follows the hinged door when the hinged door is opened, most of the powder is quickly sucked into the exhaust side. Therefore, contamination outside the unit can be avoided and suppressed.

About the clean room unit for dispensing of such this invention, the specific form for implementing this is demonstrated by the following Examples 1-2.
Example 1 shown in FIG. 1 embodies the above-described solving means 1 to 3 (claims 1 to 3 at the beginning of application) and Embodiments 1 and 2, and Example 2 shown in FIG. The above-described solving means 4 to 5 (claims 4 to 5 at the beginning of the application) and embodiments 3 to 6 are embodied.
In the drawings, for the sake of simplification and the like, fasteners such as bolts, coupling tools such as hinges, details of electric circuits and electronic circuits, etc. are omitted and related to what is necessary for explaining the invention. The figure is centered on things.

  A specific configuration of Example 1 of the clean room unit for dispensing according to the present invention will be described with reference to the drawings. 1A is a longitudinal sectional view of a building 10 as an installation destination showing the installation state of the clean room unit 20, FIG. 1B is a front view showing the entire appearance of the clean room unit 20, and FIG. FIG. 3 is an internal schematic diagram showing the air flow path (supply / exhaust path) of the air, and FIG.

  The clean room unit 20 is a dispensing clean room unit that is independently installed inside the building 10 (see FIG. 1 (a)) in the same manner as the known products described above (see Patent Document 1). The working unit 30, the clean bench 40, and the pass unit 50 are installed on the bottom 21 so as to be suitable for performing a dispensing operation (see FIG. 1B). The clean bench 40 and the pass unit 50 are connected to each other and are housed in an integral housing that can be sealed.

  However, unlike such known products, the clean room unit 20 follows the previously described undisclosed improved products (see Patent Document 2) and further improves. Specifically, the air supply duct 12 exiting from the clean room unit 20 extends to the outside of the building 10 so as to be able to take in outside air from the outside air intake 11, and the exhaust ducts 13 and 14 exiting from the clean room unit 20. After merging, after passing through the exhaust side damper 15 (yin / yang switching damper), the filter, and the blower 16, it extends to the outside of the building 10 so that the exhaust sucked out from the clean room unit 20 can be discharged from the outdoor exhaust port 17 to the outside. Yes.

  The work unit 30 (see FIG. 1 (c)) also includes a ceiling back 31 that incorporates the fans 72 and 74 and takes in air from the air supply duct 12, and a hinged door 60 for entering and leaving the worker, as in the above-described product. Equipped at the front, when closed, it is isolated from the outside, and a work room 34 that can secure a sealed space sufficient for the performance of dispensing work by one or a small number of people, and gently clean from the ceiling 31 to the work room 34 An air supply port 32 for sending air and an air supply port 33 for blowing an air shower from the ceiling back 31 to the work room 34 are provided.

  The clean bench 40 includes a work table 41 having a dispensing work space secured on the work table, and a table air inlet provided on the back side of the work table 41 for sucking air from the dispensing work space and sending it to the exhaust side. 43, a communication passage 44 for guiding the exhaust gas to the exhaust duct 13 and a ceiling back 45, the front end of the work table 41 and the work opening on the work table 34 facing the work room 34, The work opening is opened and closed by the shutter 42. A drive mechanism (not shown) is added to the shutter 42 so that the shutter 42 can be opened and closed not only manually but also automatically. In addition, a platform inlet 46 is provided below the platform 41, and the air in the work room 34 is sucked out from the platform and led to the exhaust duct 14 via the communication passage 47, the passage of the bottom portion 21 and the like. Yes.

  The pass unit 50 may be said to be a part of the work unit 30, and the pass box 51 that allows taking in and out of accessories and cleaning with the hinged door 60 closed, and sucks out air from the work room 34 from above. In order to exhaust the air, a box-side intake port 52 provided on the rear side of the pass box 51, a communication passage 53 for guiding the exhaust to the exhaust duct 14, and a ceiling back 54 are provided. Under the pass box 51, a lower box air intake 55 is provided so that the air in the work room 34 can be sucked out from there and led to the exhaust duct 14 via the communication path 56 and the communication path 53. It has become.

In the air supply / exhaust system (see FIG. 1 (d)), the air supply side and the exhaust side are completely separated, and only air taken from outside is used for supplying air to the work room 34, and a clean bench All the exhaust from 40 is sent to the outdoors.
The air supply system will be described in detail. The outside air is taken into the building 10 from the outside air inlet 11, the air is sent to the ceiling 31 by the air supply duct 12, cleaned by the filter 71, and then the blower 72 is operated to mute the air. If clean air is gently supplied to the work room 34 through the air compressor 73 and the air supply port 32 and the blower 74 is operated, the clean air is vigorously supplied through the silencer 75 and the air supply port 33. Therefore, in addition to supplying clean air during steady operation, air shower for dust removal after entering the room can be performed in the work room 34. An air supply side damper 18 that can vary the degree of opening (opening degree) is inserted and connected to the air supply duct 12.

In addition, the exhaust system exhausts air from the top intake port 43 to the exhaust duct 13 by the blower 76 in the ceiling 45, and from the top intake port 52 and the bottom intake port 55 to the exhaust duct 14 by the blower 77 in the ceiling 54. After exhausting and merging both exhausts, the air is sent out from the outdoor exhaust port 17 by the blower 16 via the exhaust side damper 15 to the outside. Although illustration is omitted, in the exhaust system, for example, in the exhaust ducts 13 and 14, the ceiling backs 45 and 54, etc., in order to prevent environmental destruction due to the outdoor discharge of the powder or dust, the powder or dust Built-in filter to capture.
The air supply / exhaust system including the air supply system and the exhaust system supplies only clean air taken in from outside air to the work room 34 without circulating all of the air in the unit. It is discharged to the outdoors via the clean bench 40 and the pass unit 50.

  Moreover, since the back pressure changes by adjusting the variable opening degree (opening degree) of the exhaust side damper 15 (yin / yang switching damper), the upstream air pressure can be adjusted, and the air supply side By adjusting the opening degree of the damper 18 together, the negative pressure can be easily enhanced. A motor-driven electric damper suitable for continuously varying the opening degree is employed for both the exhaust-side damper 15 and the supply-side damper 18, and the motor is controlled by, for example, a control device 22 incorporated in a microprocessor. Since the exhaust gas damper 15 and the air supply side damper 18 change the opening of the air supply / exhaust path of the air supply / exhaust system according to the control of the control device 22 because the signals and the operation commands are received. It is a damper that performs switching.

  Further, in addition to the dampers 15 and 18, the blowers 16, 72, 74, 76 and 77 are also controlled by the control device 22, and the control device 22 is operated via an operation panel (not shown). The pressure in the work room 34 can be switched to a negative pressure, a normal pressure, or a positive pressure. As described above, negative pressure is suitable for the dispensing work of powerful drugs such as anticancer agents, and positive pressure is suitable for the dispensing work of other drugs. The control device is based on the premise that the motors and drive circuits of the fans 16, 72, 74, 76, 77 are of inverter control type, and that each air volume can be set arbitrarily and can be varied steplessly. No. 22 gradually increases the air volume by, for example, about 10 seconds when starting each blower, and in the subsequent steady state, the air volume is somewhat changed by, for example, so-called “1 / f fluctuation”.

  Further, the clean room unit 20 is equipped with a differential pressure indicator 80, several differential pressure gauges 81 to 86, a normally closed damper 90, and a damper operation member (not shown). The differential pressure indicator 80 is attached to the inside of the work room 34 so as to be easily visible (see FIG. 1C), and the fine differential pressure gauges 81 to 86 are dispersed in various places in the supply / exhaust path of the supply / exhaust system. The normally closed damper 90 is fitted in a through hole in the wall of the work room 34 of the work unit 30 in combination with a filter (see FIG. 1B). ) The damper operation member may be embodied as a part of the operation panel described above, but here, it is formed of a separate member such as a push button, and is provided on either or both of the outer wall and the inner wall of the work room 34. On the other hand, it is attached to a site suitable for visual recognition and manual operation.

  The normally closed damper 90 is, for example, an electric damper driven by a motor, but may be a small one. The normally closed damper 90 is closed in a normal state, but communicates the inside and outside of the work room 34 when opened. The damper operating member for instructing the opening operation of the normally closed damper 90 may be configured to control the operation of the normally closed damper 90 alone, but in this embodiment, the damper operating member is operated by, for example, finger pressing. Then, a signal reporting the operation is sent to the control device 22. Further, the normally closed damper 90 is opened only when an opening command is received from the control device 22 and closed at other times. Further, when the control device 22 receives a signal reporting the operation from the damper operation member, the control device 22 adds a slight margin to the time required for the opening / closing operation normally required for manually opening and closing the hinged door 60, for example 10 The normally closed damper 90 is opened and the exhaust side damper 15 and the air supply side damper 18 are fully opened over a time period of about 2 seconds.

  For the differential pressure gauges 81 to 86, for example, a sensor that converts a capacitance change caused by a minute displacement of a stainless steel diaphragm into a DC voltage and outputs it is used because it is small and easy to use. The outputs of the micro differential pressure gauges 81 to 86 may be sent directly to the differential pressure indicator 80 via a signal cable or the like. In this embodiment, first, the output is sent to the control device 22, and then the differential pressure indicator. 80 is transferred. The fine differential pressure gauge 81 (see FIG. 1A) is attached to the air supply duct 12 so as to detect a differential pressure inside and outside the supply passage. The fine differential pressure gauge 82 is connected to the exhaust duct 13. , 14 to detect the differential pressure inside and outside the exhaust path. Moreover, the fine differential pressure gauge 83 is mounted on the outer wall of the ceiling 31 of the work unit 30 and detects the pressure difference inside and outside the air supply path (see FIG. 1C).

  Further (see FIG. 1C), the differential pressure gauge 84 is a partition wall between the ceiling back 31 of the work unit 30 and the ceiling back 45 of the clean bench 40, and the ceiling back of the work unit 30 and the pass unit 50. 54 is attached to a partition wall 54, and the pressure difference between the two paths is detected where the air supply path and the exhaust path pass each other. The differential pressure gauge 85 is attached to the side of the air supply port 32 to which the filter is attached, the table intake port 43, the table intake port 46, the box intake port 52, and the box intake port 55. Two differential pressures located upstream and downstream of the opening filter in the exhaust path are detected. The differential pressure gauge 86 is attached to the frame portion of the work opening on the front end of the work bench 41 of the clean bench 40, the upper partition wall, or the like, and the internal space of the work room 34 and the dispensing work space above the work bench 41 are arranged. The differential pressure is detected.

  The control device 22 and the differential pressure indicator 80 share the processing of the detection results of the micro differential pressure gauges 81 to 86 as appropriate, and the detection results of the micro differential pressure gauges 81 to 86 are classified according to whether the detection results are normal or abnormal. In addition to displaying on the differential pressure indicator 80, if any one of them is abnormally displayed, an alarm sound is emitted from the differential pressure indicator 80. In addition to normal or abnormal, it may be divided to the middle, for example, if the absolute value of the differential pressure is below a predetermined value, it is displayed in blue as a normal level, and if the absolute value of the differential pressure is a little over that, be careful The level is displayed in yellow and the buzzer sounds intermittently weakly. If the absolute value of the differential pressure greatly exceeds a predetermined value, the abnormal level is displayed in red and the buzzer sounds continuously and strongly.

  Further, the control device 22 performs further processing on the differential pressure detected by the micro differential pressure gauge 86. When the differential pressure becomes negative, some automatic processing is performed depending on the degree. Is selected and executed. Specifically, a state in which the air pressure in the dispensing work space above the work table 41 of the clean bench 40 is higher than the air pressure in the work room 34 is an instantaneous time that can be regarded as air pulsation, signal noise, or the like. Apart from that, when it continues continuously and intermittently, it is determined that an abnormal state in which the differential pressure has become negative has occurred.

  When the absolute value of the differential pressure exceeds the first threshold value, guidance for workers that prompts the work opening on the front end of the work table 41 to close, such as “Please close the shutter of the clean bench more” Is displayed on the differential pressure indicator 80, and when the abnormal level rises and the absolute value of the differential pressure exceeds the second threshold value, the shutter 42 is automatically closed, and the abnormal level rises to increase the differential pressure. When the absolute value exceeds the third threshold, the normally closed damper 90 is automatically opened.

  The use mode and operation of the clean room unit 20 of the first embodiment will be described with reference to the drawings. FIG. 1A is a longitudinal sectional view of an installation building 10 showing the installation state of the clean room unit 20, and FIG. 1C is an internal schematic diagram showing the air flow in the clean room unit 20 with arrows. .

  Although the clean room unit 20 is independently installed inside the building 10 (see FIG. 1A), the outdoor air intake port 11 at the front end of the air supply duct 12 and the outdoor exhaust port 17 at the front ends of the exhaust ducts 13 and 14 are provided in the building. When the air supply / exhaust system is activated, outside air is taken into the air supply system of the clean room unit 20 from the outside, and the exhaust from the exhaust system of the clean room unit 20 is released to the outside through the outdoor exhaust port 17. Is done. With respect to the openings other than the supply / exhaust system, the principle of operation is that the hinged door 60 is closed except when the operator enters and exits. Is also closed.

  In the clean room unit 20, the air taken from the outside is purified and sent to the work room 34. In addition, only air taken from outside is used to supply air to the work room 34. A part of the air in the work room 34 is guided to the exhaust duct 13 via the dispensing work space on the work table 41 of the clean bench 40 and the air intake 43 on the table, and the rest is a pass box of the pass unit 50. 51, led to the exhaust duct 14 through the work space above the box 51, the box upper inlet 52, the box lower inlet 55 below the pass box 51, and the base inlet 46 below the work bench 41 of the clean bench 40; All of these exhaust air is cleaned again and finally released outdoors.

  In order to perform dispensing using the clean room unit 20 that performs such air supply / exhaust, first, the damper operation member is manually operated by finger pressing or the like while the air supply / exhaust is stopped. Then, the air supply side damper 18 and the exhaust side damper 15 are fully opened and the normally closed damper 90 is opened, and the state is maintained for about 10 seconds longer than the time required for the opening / closing operation. A person enters the work room 34 and further closes the hinged door 60. As a result, the air flow caused by the opening / closing of the hinged door 60 escapes into and out of the unit without being confined in the work room 34, so that a sudden change in atmospheric pressure in the work room 34 when the hinged door 60 is opened / closed is alleviated. Therefore, the worker can enter the work room 34 comfortably.

  Then, intake / exhaust is started. At that time, the exhaust fans 76, 77, and 16 are collectively operated without being selected, while the air supply fans 72 and 74 are selectively operated. Specifically, the blower 74 is operated only when an air shower is necessary for dust removal after entering the room, and thereafter, only the blower 72 is operated. The shutter 42 is left open. Since the blowers 16, 72, 74, 76, and 77 are inverter-controlled, the power consumption is small and the operation cost is saved. When the blower is started, that is, when the air flow starts, the air volume increases gently, and the air volume fluctuates moderately in the subsequent calm operation state, that is, the steady state, so that the worker continues to work comfortably even in the work room 34. be able to.

  In the work room 34 in which such air supply / exhaustion continues, the worker cleans the upper surface of the work table 41 of the clean bench 40, the inner wall surface of the work room 34, and the like. However, as described above, only air taken from outside is used for supplying air to the work room 34. In addition, since all the exhaust from the clean bench 40 and the pass unit 50 is taken out outdoors, the air in the clean room unit 20 is quickly replaced, and the cleanliness of the air is improved in a short time. The waiting time is shorter than before.

  Then, when the air in the work room 34 or the like becomes sufficiently clean, the dispensing work is performed in the dispensing work space on the work table 41. Prior to that, the supply side damper 18 and the exhaust side damper 15 (yin / yang switching damper) are performed. When dispensing powerful drugs such as anti-cancer drugs by adjusting the opening degree, the work room 34 is set to a negative pressure to prevent external leakage of drugs, and when other drugs are dispensed, intrusion of contaminants To prevent this, the working room 34 is kept at a positive pressure. In addition, the delivery of the medicine to be dispensed and the delivery of the dispensed medicine are performed via the pass box 51 so that the hinged door 60 can be opened and closed in a short time.

  At that time, the powder and the like that have risen by the dispensing work on the work table 41 are carried by the air current and discharged from the air intake 43 on the table, and are carried to the exhaust duct 13 instead of the work room 34, and are carried in and out on the pass box 51. Dust and dust that have risen due to the like are sucked out from the communication passage 53 and carried to the communication passage 44 instead of the work room 34. Further, the powdered powder or the like that falls from the work table 41 toward the work room 34 is sucked out from the under air intake 46, and the dust that has fallen down from the top of the pass box 51 toward the work room 34 is taken into the under air intake 55. All are sucked out of the air and carried to the communication path 53. And since it is captured by the filter incorporated in the exhaust system, only the exhaust is discharged from the outdoor exhaust port 17 to the outside without damaging the environment.

  After the dispensing work is completed, the operation of the air supply / exhaust system is stopped, and the worker in the work room 34 waits for the air flow by the air supply / exhaust system to be felt in the work room 34 and then closes the shutter 42 to work. The dispensing work space on the table 41 and the work room 34 are partitioned, and then the hinged door 60 is gently opened to exit the work room 34. When leaving the work room 34, the damper operating member is also opened prior to opening and closing the hinged door 60. Manually operate by pressing the key. Then, the supply-side damper 18 and the exhaust-side damper 15 are fully opened, and the normally-closed damper 90 is opened, and the state is maintained for about 10 seconds longer than the opening / closing operation required time. An operator leaves the work room 34 and further closes the hinged door 60. Also by this, the air flow caused by opening and closing the hinged door 60 escapes into and out of the unit without being confined in the work room 34, so that a sudden change in atmospheric pressure in the work room 34 when the hinged door 60 is opened and closed is alleviated. Therefore, the worker can get out of the work room 34 comfortably.

Thus, in the dispensing operation using the clean room unit 20, the operation can be started more quickly than before, and the operation can be completed in a shorter time.
In addition, it is possible to avoid a sudden change in atmospheric pressure in the work room 34 due to opening and closing of the hinged door 60 by simply pressing the damper operating member.
Even when powerful medicine enters the work room 34 from the work table 41 undesirably, the drug is quickly discharged from the top and bottom of the work table 41, so that the risk of exposure to the worker is small.

The above is an explanation relating to normal operation. However, in the clean room unit 20 of the present invention, the occurrence of damage can be prevented in advance or reduced even when abnormal.
That is, if the differential pressure detected by the fine differential pressure gauges 81 to 86 is in the normal range, each detection result is displayed in blue on the differential pressure indicator 80. Since it is displayed in yellow on the differential pressure indicator 80 and a weak warning sound is emitted, the operator in the work room 34 is alerted and can be prepared. Further, when the differential pressure detected by the micro differential pressure gauges 81 to 86 reaches an abnormal level, the differential pressure indicator 80 displays a noticeable red and a strong warning sound is generated so as not to miss it. The workers inside are prompted to take countermeasures, so they can take the necessary countermeasures.

  Further, when an abnormality occurs when the detected differential pressure of the micro differential pressure gauge 86 becomes negative, an appropriate automatic process selected according to the degree is executed. That is, in the case of a slight abnormality in which the absolute value of the differential pressure exceeds the first threshold, a guidance “Please close the shutter of the clean bench more” is presented on the differential pressure indicator 80, so the operator For safety, the dispensing operation is interrupted, and the shutter 42 is manually operated to close the work opening on the front end of the work table 41. Still, when the abnormal level increases and the absolute value of the differential pressure exceeds the second threshold value, the shutter 42 is automatically closed by the determination and control of the control device 22, and the abnormal level increases and the absolute value of the differential pressure exceeds the third threshold value. The normally closed damper 90 is automatically opened by the determination and control of the control device 22. Thus, the air backflow from the dispensing work space on the work table 41 to the work room 34 is blocked many times, so that it is possible to prevent the undesired exposure of the operator due to the powerful drug on the work table 41 with high accuracy. it can.

  About the Example 2 of the clean room unit for dispensing of this invention, the specific structure is demonstrated referring drawings. 2A is an external view of the door periphery when the hinged door 60 is closed, FIG. 2B is an interior view of the door periphery at that time, and FIG. 2C is an opening / closing operation member 61 for opening the hinged door 60. (D) is an interior view of the door periphery at that time, (e) is a cross-sectional view of the door periphery when the hinged door 60 is opened, and (f) is supplied. It is a block diagram which shows the remodeling part of an exhaust system.

This dispensing clean room unit is different from the clean room unit 20 of the first embodiment described above in the modification around the hinged door 60, which is a door opening / closing indicator 63, an operation detector 64, an opening / closing detector 65, and a door inlet. 23 and the opening / closing damper 24 are added, and the function of the control device 22 is enhanced with the addition thereof.
The hinged door 60 itself may be the same as described above. The illustrated hinged door 60 employs a single hinged door that is excellent in hermeticity and inexpensive and requires a small area on the wall surface. It is attached to. In the hinged door 60, an opening / closing operation member 61 formed of a rotary handle protrudes inside and outside (front and back), and a locking member 62 such as a slide rod is internally provided.

  As long as the entrance / exit frame member 35 of the work unit 30 corresponds to the hinged door 60, this may be the same as the above-described product. A hole-like locked portion 36 into which the front end of the door can be inserted is formed, and a hinge supporting the hinged door 60 is attached to the other vertical frame. When the opening / closing operation member 61 is manually operated, the locking member 62 is completely retracted and the engagement between the locking member 62 and the locked portion 36 is canceled. When the opening / closing operation member 61 is released and freed, the opening / closing operation member 61 reversely rotates and returns to its original state and the tip of the locking member 62 protrudes. The stop member 62 and the locked portion 36 are engaged with each other so that the closed state is maintained. In addition, since it does not lock, the function and member are unnecessary.

The door opening / closing indicator 63 is, for example, a liquid crystal panel that displays guidance text and symbols in accordance with the control of the control device 22. Is attached.
The operation detector 64 is composed of, for example, a photo sensor or a push switch, and detects the state of the opening / closing operation member 61. Since it is simpler and cheaper to be placed on the side of the main body 34, it is provided on the entrance / exit frame member 35 facing the locked portion 36, and indirectly by detecting the advancing / retreating state of the locking member 62 interlocking with the opening / closing operation member 61. The state of the opening / closing operation member 61 is detected.

The operation detector 64 may be a photo sensor or a push switch, for example, but the operation detector 64 is provided in the entrance / exit frame member 35 and can directly detect the opening / closing of the hinged door 60, and the detection result is also The control device 22 is notified.
The under-door air inlet 23 may be the same as the above-described table-top air inlet 43 or the like, and may be, for example, a number of small holes formed in a punching metal, below the hinged door 60 in the outer surface surrounding the work room 34. It is formed in the part of the bottom 21 located.
The under-door intake port 23 is connected to the communication path of the bottom portion 21 with an open / close damper 24 interposed therebetween. The open / close damper 24 opens and closes according to the control of the control device 22, so that the air supply / exhaust system can Is to be done selectively.

  The function of the control device 22 is extended so that the door opening / closing indicator 63 performs guidance display related to the opening / closing of the hinged door 60 based on the detection result of the opening / closing detector 65 and the state of the operation control for the air supply / exhaust system. Specifically, when an attempt is made to operate the air supply / exhaust system even when the hinged door 60 is open, a guidance such as “Please close the door before starting supply / exhaust” is displayed. "You can start", and during the air supply and exhaust, "Please stop the air supply and exhaust before opening the door" is displayed, and when the open door 60 opens during the air supply and exhaust, “Please close the door” is displayed.

  In addition, the control device 22 knows whether or not the air supply / exhaust is being performed based on the state of the operation control on the air supply / exhaust system, and the opening / closing operation member 61 is rotated so that the front end of the locking member 62 and the locked state When the engagement with the part 36 is released or is canceled, the operation detector 64 notifies the detection result, and the opening operation of the hinged door 60 prior to the opening operation of the hinged door 60 can be detected. When the opening operation of the hinged door 60 is performed during exhaust, the work opening on the front end of the work table 41 is closed by the shutter 42, and the opening / closing damper 24 is slightly opened so that the air supply / exhaust system can The intake is made weak.

Further, when the control device 22 detects the opening operation of the hinged door 60 during supply / exhaust and then detects the opening operation of the hinged door 60 during supply / exhaust based on the detection result of the opening / closing detector 65, the control device 22 temporarily, for example, 1 The exhaust air is strengthened in the air supply / exhaust system by, for example, maximizing the rotation speed of the blowers 76, 77, 16 for about 2 seconds, and the open / close damper 24 is opened widely to allow the air supply / exhaust system to be The intake is strongly performed.
Further, since the control device 22 knows the open / closed state of the hinged door 60 based on the detection results of the opening / closing detector 65 and the operation detector 64 as described above, the normally-closed damper 90 and the supply side damper 18 are opened when the hinged door 60 is opened / closed. And the exhaust side damper 15 is opened.

  Specifically, when the hinged door 60 is closed, the normally closed damper 90 is completely closed, and the normally closed damper 90 and the air supply side damper 18 are closed or in a half-open state necessary for pressure adjustment or the like. On the other hand, when the opening operation of the hinged door 60 is detected based on the detection result of the operation detector 64 and it is determined that the hinged door 60 is about to open or not fully closed, the hinged door 60 is opened based on the detection result of the opening / closing detector 65. When it is determined that the normal damper 90, the supply-side damper 18 and the exhaust-side damper 15 are completely opened.

When the dispensing clean room unit of Example 2 is used, the basic usage and operation are the same as those of the above-described clean room unit 20, and therefore, repeated description will be omitted, and operations corresponding to the function expansion will be described in detail.
Even if the operator forgets to press the damper operating member when entering the work room 34, when the hinged door 60 is opened, the normally closed damper 90, the supply side damper 18, and the exhaust side damper 15 are automatically opened accordingly. The dampers 90, 18, and 16 are not closed until the worker enters the work room 34, closes the hinged door 60, and releases the opening / closing operation member 61. The change in atmospheric pressure is gentle and no discomfort is caused to the operator.

In addition, when the operator opens the hinged door 60 and enters the work room 34, the operator tries to operate the air supply / exhaust system without closing the hinged door 60 properly. “Please close” is displayed, so contamination due to forgetting to close can be avoided.
If the hinged door 60 is closed, the door opening / closing indicator 63 displays a message that “supply / exhaust can be started”, so that the operator can start supplying / exhausting with peace of mind.

  Furthermore, during the air supply / exhaust operation, the door opening / closing indicator 63 displays a message “Please stop air supply / exhaust before opening the door”, so even if the door 60 is not locked, it is inadvertently supplying / exhausting. Undesirable actions that open the hinged door 60 are suppressed. Nevertheless, when the worker feels dangerous, the hinged door 60 is not locked, so that emergency escape can be made. When the hinged door 60 is opened during supply and exhaust, guidance is displayed on the door open / close indicator 63 "Please hurry to exit the room and close the door", and the suppression of cross-contamination inside and outside the unit is promoted.

  Moreover, when the operator operates the opening / closing operation member 61 to open the hinged door 60, the opening operation of the hinged door 60 is detected by the control device 22, and when it is performed during supply and exhaust, the hinged door 60 is actually opened. In advance, the shutter 42 is automatically closed in advance, and the dispensing work space on the work table 41 and the work room 34 are partitioned, and the normally closed open / close damper 24 is slightly opened so that intake air is weak from the under-door intake port 23. But it starts. Then, when the operator pushes open the hinged door 60, the control device 22 detects the opening operation of the hinged door 60 during supply and exhaust, temporarily enhancing the exhaust via the clean bench 40 and the pass unit 50, and opening and closing. The damper 24 opens widely, and the intake air from the door lower intake port 23 is also strengthened.

  Thus, when it is predicted that the hinged door 60 will be opened by operating the opening / closing operation member 61 during supply / exhaust, the dispensing work space of the clean bench 40 and the internal space of the work room 34 are immediately partitioned, and the intake port under the door 23, when the opening door 60 is actually pushed and opened, both the exhaust via the clean bench 40 and the suction from the lower door inlet 23 become stronger. Even if the air pressure in the work room 34 temporarily drops when the door is pushed open, the amount of powder and the like flowing into the work room 34 from the dispensing work space can be suppressed to a small level, and the air flow following the open door 60 is taken. It is possible to slightly suppress powdered medicine remaining on the floor from the work room 34.

  Further, when the worker who has finished the work leaves the work room 34 and also tries to open the hinged door 60 without forgetting to press the damper operating member, the normally closed damper 90 and the air supply side damper are automatically and quickly responded accordingly. 18 and the exhaust side damper 15 are opened. Since the dampers 90, 18, and 16 are not closed until the operator opens the hinged door 60 and exits from the work room 34, and further closes the hinged door 60 and releases the opening / closing operation member 61. Since the change in the atmospheric pressure in the work room 34 when the hinged door 60 is opened and closed is gentle, the operator does not feel uncomfortable.

[Others]
In the above embodiment, when the control device 22 detects the opening operation of the hinged door 60 during supply / exhaust based on the detection result of the operation detector 64, the control device 22 sends the intake air from the door lower intake port 23 to the supply / exhaust system. The control device 22 is not started, but the control device 22 detects the opening operation of the hinged door 60 during supply / exhaust based on the detection result of the opening / closing detector 65. Alternatively, intake from the under-door intake port 23 may be started.
In the above embodiment, the opening / closing operation member 61 is a rotary handle. However, the opening / closing operation member 61 may have any other shape as long as it can open and close the hinged door 60 by manual operation, for example, a rotary knob, A push-pull handle may be used.

Furthermore, in the above-described embodiment, the locking member 62 is a slide rod / advanced / retracted rod, but the locking member 62 performs locking and unlocking with respect to the receiving portion 36 according to the operation of the opening / closing operation member 61. Any other shape may be used as long as it can be performed, for example, a rotary hook or a hook.
Although not mentioned in the above embodiment, a pass box with a disinfecting function may be connected to the work unit 30 or the pass unit 50, may be equipped with a driving indicator light or an intercom, or a chair may be put on. A human sensor may be attached, a viewing window may be provided, a plurality of illuminations may be provided, a sensor for detecting the open / closed state of the shutter 42 may be provided, and a display for displaying dispensing instructions, drug information, etc. May be provided.

10 ... building, 11 ... outside air intake,
12 ... Air supply duct, 13, 14 ... Exhaust duct,
15 ... Exhaust side damper, 16 ... Blower, 17 ... Outdoor exhaust port, 18 ... Supply side damper,
20 ... Clean room unit,
21 ... Bottom part, 22 ... Control device, 23 ... Underdoor inlet, 24 ... Opening / closing damper,
30 ... Work unit, 31 ... Ceiling, 32 ... Air inlet,
33 ... Fume port, 34 ... work room, 35 ... entrance / outlet frame material, 36 ... locked portion,
40 ... clean bench, 41 ... workbench, 42 ... shutter,
43 ... Upper air inlet, 44 ... Communication passage, 45 ... Ceiling back, 46 ... Under air intake, 47 ... Communication passage,
50 ... pass unit, 51 ... pass box, 52 ... box air inlet,
53 ... Communication passage, 54 ... Back of the ceiling, 55 ... Inlet under the box, 56 ... Communication passage,
60 ... Swing door (single door), 61 ... Opening / closing operation member,
62 ... Locking member, 63 ... Door open / close indicator, 64 ... Operation detector, 65 ... Open / close detector,
71 ... filter, 72 ... blower, 73 ... silencer,
74 ... blower, 75 ... silencer, 76,77 ... blower,
80 ... Differential pressure indicator, 81-86 ... Fine differential pressure gauge, 90 ... Normally closed damper

Claims (2)

A work room that has a hinged door for entering and exiting a worker and is isolated from the outside when the door is closed, a clean bench that faces one end of the work table and a work opening on the work room, and the work room. A pressure-adjustable air supply / exhaust system that exhausts air from the clean bench while supplying clean air, and when controlling the operation of the air supply / exhaust system, the air pressure in the working room is switched to negative pressure or other pressures. In the clean room unit for dispensing, which is equipped with a control device that enables the dispensing work to be performed and is installed independently inside the building,
A damper that switches the air pressure of the work room by changing the opening of the air supply / exhaust path of the air supply / exhaust system according to the control of the control device is provided in the air supply / exhaust system, and the control device When opening and closing, the damper is fully opened ,
Furthermore, a damper operating member for instructing the opening operation of the damper is provided, and the damper is opened longer than the time required for opening and closing the hinged door according to the operation of the damper operating member, thereby opening and closing the hinged door. A clean room unit for dispensing, characterized in that the damper is opened. A work room that has a hinged door for entering and exiting a worker and is isolated from the outside when the door is closed, a clean bench that faces one end of the work table and a work opening on the work room, and the work room. A pressure-adjustable air supply / exhaust system that exhausts air from the clean bench while supplying clean air, and when controlling the operation of the air supply / exhaust system, the air pressure in the working room is switched to negative pressure or other pressures. In the clean room unit for dispensing, which is equipped with a control device that enables the dispensing work to be performed and is installed independently inside the building,
While closed in normal Hirakiji damper for communicating the inside and outside of the working room is equipped to the working room, at the time of opening and closing of the hinged door being adapted to open the damper,
Furthermore, a damper operating member for instructing the opening operation of the damper is provided, and the damper is opened longer than the time required for opening and closing the hinged door according to the operation of the damper operating member, thereby opening and closing the hinged door. A clean room unit for dispensing, characterized in that the damper is opened.

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