JP5242374B2 - 組成物ならびに長期効力を得るための医療機器を用いたラパマイシン類縁体の投与方法 - Google Patents

組成物ならびに長期効力を得るための医療機器を用いたラパマイシン類縁体の投与方法 Download PDF

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Publication number
JP5242374B2
JP5242374B2 JP2008503210A JP2008503210A JP5242374B2 JP 5242374 B2 JP5242374 B2 JP 5242374B2 JP 2008503210 A JP2008503210 A JP 2008503210A JP 2008503210 A JP2008503210 A JP 2008503210A JP 5242374 B2 JP5242374 B2 JP 5242374B2
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Prior art keywords
stent
zotarolimus
drug
rapamycin
days
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Expired - Fee Related
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JP2008503210A
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Japanese (ja)
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JP2008534074A (ja
JP2008534074A5 (enExample
Inventor
トナー，ジヨン・ケイ
バーク，サンドラ・イー
クロマツク，キース・アール
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Abbott Laboratories
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Abbott Laboratories
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
JP2008503210A 2005-03-23 2006-03-22 組成物ならびに長期効力を得るための医療機器を用いたラパマイシン類縁体の投与方法 Expired - Fee Related JP5242374B2 (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US66448805P 2005-03-23 2005-03-23
US60/664,488 2005-03-23
US71508205P 2005-09-08 2005-09-08
US60/715,082 2005-09-08
US72687805P 2005-10-14 2005-10-14
US72708005P 2005-10-14 2005-10-14
US72719605P 2005-10-14 2005-10-14
US60/726,878 2005-10-14
US60/727,196 2005-10-14
US60/727,080 2005-10-14
US73257705P 2005-10-17 2005-10-17
US60/732,577 2005-10-17
PCT/US2006/010700 WO2007032777A2 (en) 2005-03-23 2006-03-22 Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacy

Publications (3)

Publication Number Publication Date
JP2008534074A JP2008534074A (ja) 2008-08-28
JP2008534074A5 JP2008534074A5 (enExample) 2009-04-30
JP5242374B2 true JP5242374B2 (ja) 2013-07-24

Family

ID=37865406

Family Applications (1)

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JP2008503210A Expired - Fee Related JP5242374B2 (ja) 2005-03-23 2006-03-22 組成物ならびに長期効力を得るための医療機器を用いたラパマイシン類縁体の投与方法

Country Status (3)

Country Link
EP (2) EP3138531A1 (enExample)
JP (1) JP5242374B2 (enExample)
WO (1) WO2007032777A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8394398B2 (en) 1997-09-26 2013-03-12 Abbott Laboratories Methods of administering rapamycin analogs with anti-inflammatories using medical devices
US7357942B2 (en) 1997-09-26 2008-04-15 Abbott Laboratories Compositions, systems, and kits for administering zotarolimus and paclitaxel to blood vessel lumens
US8257726B2 (en) 1997-09-26 2012-09-04 Abbott Laboratories Compositions, systems, kits, and methods of administering rapamycin analogs with paclitaxel using medical devices
US7378105B2 (en) 1997-09-26 2008-05-27 Abbott Laboratories Drug delivery systems, kits, and methods for administering zotarolimus and paclitaxel to blood vessel lumens
US8431145B2 (en) 2004-03-19 2013-04-30 Abbott Laboratories Multiple drug delivery from a balloon and a prosthesis
EP2068932B1 (en) * 2006-08-15 2013-11-06 Abbott Laboratories Compositions and drug-delivery systems comprising rapamycin analogs and paclitaxel
KR20100085179A (ko) 2007-09-04 2010-07-28 가부시키가이샤 니혼 스텐토 테크놀로지 약제 서방성 스텐트
US8951595B2 (en) 2009-12-11 2015-02-10 Abbott Cardiovascular Systems Inc. Coatings with tunable molecular architecture for drug-coated balloon
US20130303496A1 (en) * 2012-05-08 2013-11-14 Abbott Cardiovascular Systems Inc. Method Of Treating Vascular Lesions
US9610385B2 (en) * 2013-03-07 2017-04-04 Abbott Cardiovascular Systems Inc. Method of fabricating an implantable medical device comprising a rapamycin derivative
EP4255357A1 (en) * 2020-12-29 2023-10-11 Sino Medical Sciences Technology Inc. Drug eluting stent

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA737247B (en) 1972-09-29 1975-04-30 Ayerst Mckenna & Harrison Rapamycin and process of preparation
US3993749A (en) 1974-04-12 1976-11-23 Ayerst Mckenna And Harrison Ltd. Rapamycin and process of preparation
US4885171A (en) 1978-11-03 1989-12-05 American Home Products Corporation Use of rapamycin in treatment of certain tumors
US4316885A (en) 1980-08-25 1982-02-23 Ayerst, Mckenna And Harrison, Inc. Acyl derivatives of rapamycin
US4401653A (en) 1981-03-09 1983-08-30 Ayerst, Mckenna & Harrison Inc. Combination of rapamycin and picibanil for the treatment of tumors
US4894366A (en) 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
US4650803A (en) 1985-12-06 1987-03-17 University Of Kansas Prodrugs of rapamycin
US5527337A (en) 1987-06-25 1996-06-18 Duke University Bioabsorbable stent and method of making the same
US4916193A (en) 1987-12-17 1990-04-10 Allied-Signal Inc. Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lactides
US5092877A (en) 1988-09-01 1992-03-03 Corvita Corporation Radially expandable endoprosthesis
US4994071A (en) 1989-05-22 1991-02-19 Cordis Corporation Bifurcating stent apparatus and method
US5304121A (en) 1990-12-28 1994-04-19 Boston Scientific Corporation Drug delivery system making use of a hydrogel polymer coating
AU7998091A (en) 1990-05-17 1991-12-10 Harbor Medical Devices, Inc. Medical device polymer
JPH04230389A (ja) 1990-07-16 1992-08-19 American Home Prod Corp ラパマイシン誘導体
US5023262A (en) 1990-08-14 1991-06-11 American Home Products Corporation Hydrogenated rapamycin derivatives
PT98990A (pt) 1990-09-19 1992-08-31 American Home Prod Processo para a preparacao de esteres de acidos carboxilicos de rapamicina
US5120842A (en) 1991-04-01 1992-06-09 American Home Products Corporation Silyl ethers of rapamycin
US5120727A (en) 1991-05-29 1992-06-09 American Home Products Corporation Rapamycin dimers
US5120725A (en) 1991-05-29 1992-06-09 American Home Products Corporation Bicyclic rapamycins
US6090901A (en) 1991-07-05 2000-07-18 Biocompatibles Limited Polymeric surface coatings
US5705583A (en) 1991-07-05 1998-01-06 Biocompatibles Limited Polymeric surface coatings
US5163852A (en) 1992-02-11 1992-11-17 W. L. Gore & Associates, Inc. Coaxial cable side tape connector assembly and processes for assembly
US5177203A (en) 1992-03-05 1993-01-05 American Home Products Corporation Rapamycin 42-sulfonates and 42-(N-carboalkoxy) sulfamates useful as immunosuppressive agents
US5464650A (en) 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
US5605696A (en) 1995-03-30 1997-02-25 Advanced Cardiovascular Systems, Inc. Drug loaded polymeric material and method of manufacture
US5837313A (en) 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
US6099562A (en) 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
CA2256323C (en) 1997-03-31 2007-05-22 Kabushikikaisha Igaki Iryo Sekkei Stent for vessel
US20040213789A1 (en) * 1997-09-02 2004-10-28 Oron Yacoby-Zeevi Heparanase activity neutralizing anti-heparanase monoclonal antibody and other anti-heparanase antibodies
US20030129215A1 (en) 1998-09-24 2003-07-10 T-Ram, Inc. Medical devices containing rapamycin analogs
US8029561B1 (en) 2000-05-12 2011-10-04 Cordis Corporation Drug combination useful for prevention of restenosis
US6419692B1 (en) 1999-02-03 2002-07-16 Scimed Life Systems, Inc. Surface protection method for stents and balloon catheters for drug delivery
GB0100760D0 (en) 2001-01-11 2001-02-21 Biocompatibles Ltd Drug delivery from stents
EP2314293B1 (en) * 2001-01-16 2017-01-04 Vascular Therapies, LLC Implantable device containing resorbable matrix material and rapamycin for preventing or treating vasuloproliferative diseases
US7708712B2 (en) * 2001-09-04 2010-05-04 Broncus Technologies, Inc. Methods and devices for maintaining patency of surgically created channels in a body organ
EP1536850B1 (en) * 2002-09-06 2016-08-10 Abbott Laboratories Medical device having hydration inhibitor
KR20060052722A (ko) * 2003-08-05 2006-05-19 가부시키가이샤 가네카 생체유치용 스텐트
JP4379044B2 (ja) * 2003-08-22 2009-12-09 株式会社カネカ 生体留置用ステント
US20050208093A1 (en) * 2004-03-22 2005-09-22 Thierry Glauser Phosphoryl choline coating compositions
JP2008506507A (ja) * 2004-07-19 2008-03-06 ブロンカス テクノロジーズ， インコーポレイテッド 体器官に外科的に作製されたチャネルを維持するための方法および器具

Also Published As

Publication number Publication date
JP2008534074A (ja) 2008-08-28
EP3138531A1 (en) 2017-03-08
WO2007032777A2 (en) 2007-03-22
EP1877004A2 (en) 2008-01-16
EP1877004A4 (en) 2012-01-25
WO2007032777A3 (en) 2007-10-25

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