JP5231418B2 - 呼吸障害中の神経性刺激のためのシステム - Google Patents
呼吸障害中の神経性刺激のためのシステム Download PDFInfo
- Publication number
- JP5231418B2 JP5231418B2 JP2009526651A JP2009526651A JP5231418B2 JP 5231418 B2 JP5231418 B2 JP 5231418B2 JP 2009526651 A JP2009526651 A JP 2009526651A JP 2009526651 A JP2009526651 A JP 2009526651A JP 5231418 B2 JP5231418 B2 JP 5231418B2
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- JP
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- Prior art keywords
- respiratory
- therapy
- stimulation
- neural stimulation
- apnea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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- 238000001514 detection method Methods 0.000 claims description 62
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- 238000011282 treatment Methods 0.000 claims description 14
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 6
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Measuring devices for evaluating the respiratory organs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4029—Detecting, measuring or recording for evaluating the nervous system for evaluating the peripheral nervous systems
- A61B5/4035—Evaluating the autonomic nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4806—Sleep evaluation
- A61B5/4818—Sleep apnoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3601—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of respiratory organs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36135—Control systems using physiological parameters
- A61N1/3614—Control systems using physiological parameters based on impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Measuring devices for evaluating the respiratory organs
- A61B5/0816—Measuring devices for examining respiratory frequency
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Neurology (AREA)
- Physiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Electrotherapy Devices (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/468,603 | 2006-08-30 | ||
| US11/468,603 US8050765B2 (en) | 2006-08-30 | 2006-08-30 | Method and apparatus for controlling neural stimulation during disordered breathing |
| PCT/US2007/018697 WO2008027297A2 (en) | 2006-08-30 | 2007-08-24 | System for neural stimulation during disordered breathing |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010502276A JP2010502276A (ja) | 2010-01-28 |
| JP2010502276A5 JP2010502276A5 (enExample) | 2010-10-07 |
| JP5231418B2 true JP5231418B2 (ja) | 2013-07-10 |
Family
ID=39120704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009526651A Expired - Fee Related JP5231418B2 (ja) | 2006-08-30 | 2007-08-24 | 呼吸障害中の神経性刺激のためのシステム |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US8050765B2 (enExample) |
| EP (1) | EP2066400A2 (enExample) |
| JP (1) | JP5231418B2 (enExample) |
| AU (1) | AU2007290623B2 (enExample) |
| WO (1) | WO2008027297A2 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8121692B2 (en) | 2006-08-30 | 2012-02-21 | Cardiac Pacemakers, Inc. | Method and apparatus for neural stimulation with respiratory feedback |
| US8050765B2 (en) | 2006-08-30 | 2011-11-01 | Cardiac Pacemakers, Inc. | Method and apparatus for controlling neural stimulation during disordered breathing |
| WO2008092246A1 (en) | 2007-01-29 | 2008-08-07 | Simon Fraser University | Transvascular nerve stimulation apparatus and methods |
| US9486152B2 (en) | 2007-03-09 | 2016-11-08 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Respiratory-based control of medical procedure |
| WO2009137189A1 (en) | 2008-05-07 | 2009-11-12 | Cardiac Pacemakers, Inc. | System and method for detection of pulmonary embolism |
| US8229566B2 (en) * | 2008-06-25 | 2012-07-24 | Sheng Li | Method and apparatus of breathing-controlled electrical stimulation for skeletal muscles |
| US8844525B2 (en) * | 2008-07-25 | 2014-09-30 | Resmed Limited | Method and apparatus for detecting and treating heart failure |
| EP2575961B1 (en) | 2010-06-03 | 2018-08-29 | Cardiac Pacemakers, Inc. | System for spatially selective vagus nerve stimulation |
| EP2575959B1 (en) | 2010-06-03 | 2017-07-12 | Cardiac Pacemakers, Inc. | System for controlling target of neurostimulation using temporal parameters |
| WO2011159527A2 (en) | 2010-06-16 | 2011-12-22 | Cardiac Pacemakers, Inc. | Automatic neural stimulation titration sweep |
| EP2582429B1 (en) | 2010-06-18 | 2016-01-13 | Cardiac Pacemakers, Inc. | Neurostimulation system with control using evoked responses |
| EP2741813B1 (en) | 2011-08-11 | 2022-03-09 | Inspire Medical Systems, Inc. | System for selecting a stimulation protocol based on sensed respiratory effort |
| EP3228351B1 (en) | 2012-03-05 | 2019-06-05 | Lungpacer Medical Inc. | Transvascular nerve stimulation apparatus |
| WO2013188965A1 (en) | 2012-06-21 | 2013-12-27 | Simon Fraser University | Transvascular diaphragm pacing systems and methods of use |
| CN105873630B (zh) | 2013-11-22 | 2020-01-03 | 隆佩瑟尔医疗公司 | 用于通过经血管神经刺激辅助呼吸的装置和方法 |
| JP6537517B2 (ja) | 2014-01-21 | 2019-07-03 | ラングペーサー メディカル インコーポレイテッドLungpacer Medical Inc. | 多電極神経ペーシングの最適化のためのシステムおよび関連する方法 |
| EP2904964B1 (fr) * | 2014-02-11 | 2019-10-02 | Sorin CRM SAS | Ensemble avec dispositif médical à stimulation kinesthésique pour l'évaluation non invasive de l'équilibre sympathovagal d'un patient. |
| EP3271008B1 (en) | 2015-03-19 | 2024-09-25 | Inspire Medical Systems, Inc. | Stimulation for treating sleep disordered breathing |
| CN107920778A (zh) * | 2015-08-31 | 2018-04-17 | 皇家飞利浦有限公司 | 具有多参数过度换气警报的监测设备 |
| WO2018089789A1 (en) | 2016-11-10 | 2018-05-17 | The Research Foundation For The State University Of New York | System, method and biomarkers for airway obstruction |
| US10293164B2 (en) | 2017-05-26 | 2019-05-21 | Lungpacer Medical Inc. | Apparatus and methods for assisted breathing by transvascular nerve stimulation |
| CN111163834A (zh) | 2017-06-30 | 2020-05-15 | 隆佩瑟尔医疗公司 | 用于预防、减轻和/或治疗认知损伤的装置 |
| US10195429B1 (en) | 2017-08-02 | 2019-02-05 | Lungpacer Medical Inc. | Systems and methods for intravascular catheter positioning and/or nerve stimulation |
| US10940308B2 (en) | 2017-08-04 | 2021-03-09 | Lungpacer Medical Inc. | Systems and methods for trans-esophageal sympathetic ganglion recruitment |
| US20190175908A1 (en) | 2017-12-11 | 2019-06-13 | Lungpacer Medical Inc. | Systems and methods for strengthening a respiratory muscle |
| EP3877043B1 (en) | 2018-11-08 | 2025-04-23 | Lungpacer Medical Inc. | Stimulation systems and related user interfaces |
| WO2020123704A1 (en) | 2018-12-13 | 2020-06-18 | Livanova Usa, Inc. | Neuromodulation therapy for auto-immune and inflammatory disorders |
| US11357979B2 (en) | 2019-05-16 | 2022-06-14 | Lungpacer Medical Inc. | Systems and methods for sensing and stimulation |
| US11771900B2 (en) | 2019-06-12 | 2023-10-03 | Lungpacer Medical Inc. | Circuitry for medical stimulation systems |
Family Cites Families (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4462398A (en) * | 1982-12-03 | 1984-07-31 | Kircaldie, Randal and McNab, Trustee | Respirating gas supply method and apparatus therefor |
| US4694839A (en) * | 1986-03-24 | 1987-09-22 | Timme William F | Auxiliary stimulation apparatus for apnea distress |
| US4960129A (en) * | 1988-12-05 | 1990-10-02 | Trustees Of The University Of Pennsylvania | Methods of observing autonomic neural stimulation and diagnosing cardiac dynamical dysfunction using heartbeat interval data to analyze cardioventilatory interactions |
| JP2794196B2 (ja) * | 1989-06-20 | 1998-09-03 | チェスト株式会社 | 無呼吸防止刺激装置 |
| US5335657A (en) * | 1991-05-03 | 1994-08-09 | Cyberonics, Inc. | Therapeutic treatment of sleep disorder by nerve stimulation |
| US5205285A (en) | 1991-06-14 | 1993-04-27 | Cyberonics, Inc. | Voice suppression of vagal stimulation |
| AU2339792A (en) | 1991-07-22 | 1993-02-23 | Cyberonics, Inc. | Treatment of respiratory disorders by nerve stimulation |
| US5330507A (en) * | 1992-04-24 | 1994-07-19 | Medtronic, Inc. | Implantable electrical vagal stimulation for prevention or interruption of life threatening arrhythmias |
| BR9304546A (pt) | 1993-11-19 | 1995-08-01 | Brasilia Telecom | Processo para deposição química seguida da deposição eletrolítica de metais sobre alumina |
| US5591216A (en) * | 1995-05-19 | 1997-01-07 | Medtronic, Inc. | Method for treatment of sleep apnea by electrical stimulation |
| US5779829A (en) * | 1995-08-24 | 1998-07-14 | The Goodyear Tire & Rubber Company | Pneumatic tire having a single carcass ply reinforced with metallic cords, a high ending ply, turnup and locked bead construction |
| US7269457B2 (en) * | 1996-04-30 | 2007-09-11 | Medtronic, Inc. | Method and system for vagal nerve stimulation with multi-site cardiac pacing |
| US5954668A (en) * | 1996-06-14 | 1999-09-21 | Medrad, Inc. | Extravasation detector using microwave radiometry |
| US6021352A (en) * | 1996-06-26 | 2000-02-01 | Medtronic, Inc, | Diagnostic testing methods and apparatus for implantable therapy devices |
| US6168568B1 (en) | 1996-10-04 | 2001-01-02 | Karmel Medical Acoustic Technologies Ltd. | Phonopneumograph system |
| GB9624280D0 (en) * | 1996-11-22 | 1997-01-08 | Univ Glasgow | Apparatus and method for measuring cardiac vagal tone |
| US6141590A (en) * | 1997-09-25 | 2000-10-31 | Medtronic, Inc. | System and method for respiration-modulated pacing |
| WO1999020339A1 (en) * | 1997-10-17 | 1999-04-29 | Respironics, Inc. | Muscle stimulating device and method for diagnosing and treating a breathing disorder |
| US6251126B1 (en) * | 1998-04-23 | 2001-06-26 | Medtronic Inc | Method and apparatus for synchronized treatment of obstructive sleep apnea |
| FR2780654B1 (fr) * | 1998-07-06 | 2000-12-01 | Ela Medical Sa | Dispositif medical implantable actif permettant le traitement par electrostimulation du syndrome de l'apnee du sommeil |
| US6587725B1 (en) * | 1998-07-27 | 2003-07-01 | Dominique Durand | Method and apparatus for closed-loop stimulation of the hypoglossal nerve in human patients to treat obstructive sleep apnea |
| US6240316B1 (en) * | 1998-08-14 | 2001-05-29 | Advanced Bionics Corporation | Implantable microstimulation system for treatment of sleep apnea |
| EP1172125B1 (en) * | 2000-07-11 | 2005-03-09 | SORIN BIOMEDICA CRM S.r.l. | An implantable heart stimulation system with automatic mode switching controlled by sympatho-vagal balance |
| EP1331965B1 (en) * | 2000-10-26 | 2008-07-16 | Medtronic, Inc. | Apparatus for electrically stimulating the nervous system to improve ventricular dysfunction, heart failure, and other cardiac conditions |
| US6811538B2 (en) * | 2000-12-29 | 2004-11-02 | Ares Medical, Inc. | Sleep apnea risk evaluation |
| US20050222066A1 (en) * | 2001-05-18 | 2005-10-06 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA) |
| US7885709B2 (en) * | 2001-08-31 | 2011-02-08 | Bio Control Medical (B.C.M.) Ltd. | Nerve stimulation for treating disorders |
| US6954668B1 (en) | 2001-10-11 | 2005-10-11 | Cuozzo John W | Apparatus and method for intra-oral stimulation of the trigeminal nerve |
| US20030199945A1 (en) * | 2002-02-11 | 2003-10-23 | James Ciulla | Device and method for treating disordered breathing |
| US6928324B2 (en) * | 2002-02-14 | 2005-08-09 | Pacesetter, Inc. | Stimulation device for sleep apnea prevention, detection and treatment |
| US7689276B2 (en) * | 2002-09-13 | 2010-03-30 | Leptos Biomedical, Inc. | Dynamic nerve stimulation for treatment of disorders |
| US20030195571A1 (en) | 2002-04-12 | 2003-10-16 | Burnes John E. | Method and apparatus for the treatment of central sleep apnea using biventricular pacing |
| US20030204213A1 (en) * | 2002-04-30 | 2003-10-30 | Jensen Donald N. | Method and apparatus to detect and monitor the frequency of obstructive sleep apnea |
| US20030216789A1 (en) * | 2002-05-14 | 2003-11-20 | The Foundry, Inc. | Method and system for treating sleep apnea |
| US7277761B2 (en) * | 2002-06-12 | 2007-10-02 | Pacesetter, Inc. | Vagal stimulation for improving cardiac function in heart failure or CHF patients |
| US7252640B2 (en) * | 2002-12-04 | 2007-08-07 | Cardiac Pacemakers, Inc. | Detection of disordered breathing |
| FR2848861B1 (fr) * | 2002-12-24 | 2005-09-30 | Ela Medical Sa | Dispositif medical actif, notamment dispositif implantable tel que stimulateur cardiaque, defibrillateur, cardioverteur ou dispositif multisite, comprenant des moyens de detection des troubles du sommeil |
| US7025730B2 (en) * | 2003-01-10 | 2006-04-11 | Medtronic, Inc. | System and method for automatically monitoring and delivering therapy for sleep-related disordered breathing |
| US7438686B2 (en) * | 2003-01-10 | 2008-10-21 | Medtronic, Inc. | Apparatus and method for monitoring for disordered breathing |
| US7092755B2 (en) * | 2003-03-18 | 2006-08-15 | Pacesetter, Inc. | System and method of cardiac pacing during sleep apnea |
| US7228167B2 (en) * | 2003-04-10 | 2007-06-05 | Mayo Foundation For Medical Education | Method and apparatus for detecting vagus nerve stimulation |
| US7570997B2 (en) * | 2003-04-11 | 2009-08-04 | Cardiac Pacemakers, Inc. | Subcutaneous cardiac rhythm management with asystole prevention therapy |
| US7155278B2 (en) * | 2003-04-21 | 2006-12-26 | Medtronic, Inc. | Neurostimulation to treat effects of sleep apnea |
| US20060064137A1 (en) * | 2003-05-16 | 2006-03-23 | Stone Robert T | Method and system to control respiration by means of simulated action potential signals |
| US20060111755A1 (en) * | 2003-05-16 | 2006-05-25 | Stone Robert T | Method and system to control respiration by means of neuro-electrical coded signals |
| KR20040100763A (ko) * | 2003-05-24 | 2004-12-02 | 안문휘 | 혈압 강하기 |
| US7149574B2 (en) * | 2003-06-09 | 2006-12-12 | Palo Alto Investors | Treatment of conditions through electrical modulation of the autonomic nervous system |
| AU2003304310A1 (en) * | 2003-07-10 | 2005-01-28 | Jms Co.,Ltd. | Pacemaker system for treating sleep apnea syndrome |
| US7591265B2 (en) * | 2003-09-18 | 2009-09-22 | Cardiac Pacemakers, Inc. | Coordinated use of respiratory and cardiac therapies for sleep disordered breathing |
| US7396333B2 (en) * | 2003-08-18 | 2008-07-08 | Cardiac Pacemakers, Inc. | Prediction of disordered breathing |
| US7469697B2 (en) * | 2003-09-18 | 2008-12-30 | Cardiac Pacemakers, Inc. | Feedback system and method for sleep disordered breathing therapy |
| US7336996B2 (en) * | 2003-09-18 | 2008-02-26 | Cardiac Pacemakers, Inc. | Rate regularization of cardiac pacing for disordered breathing therapy |
| US7720541B2 (en) * | 2003-08-18 | 2010-05-18 | Cardiac Pacemakers, Inc. | Adaptive therapy for disordered breathing |
| DE10338004A1 (de) * | 2003-08-19 | 2005-04-07 | Jk-Holding Gmbh | Vorrichtung und Verfahren zur gezielten Bestrahlung des menschlichen Körpers |
| US8467876B2 (en) * | 2003-10-15 | 2013-06-18 | Rmx, Llc | Breathing disorder detection and therapy delivery device and method |
| JP2005143829A (ja) | 2003-11-14 | 2005-06-09 | Kyushu Hitachi Maxell Ltd | 低周波治療器 |
| US20050137645A1 (en) * | 2003-12-05 | 2005-06-23 | Juha Voipio | Novel method for the adjustment of human and animal vagus nerve stimulation |
| US7706884B2 (en) * | 2003-12-24 | 2010-04-27 | Cardiac Pacemakers, Inc. | Baroreflex stimulation synchronized to circadian rhythm |
| US6964641B2 (en) * | 2003-12-24 | 2005-11-15 | Medtronic, Inc. | Implantable medical device with sleep disordered breathing monitoring |
| US7509166B2 (en) * | 2003-12-24 | 2009-03-24 | Cardiac Pacemakers, Inc. | Automatic baroreflex modulation responsive to adverse event |
| US8126559B2 (en) * | 2004-11-30 | 2012-02-28 | Cardiac Pacemakers, Inc. | Neural stimulation with avoidance of inappropriate stimulation |
| US7366572B2 (en) * | 2004-03-16 | 2008-04-29 | Medtronic, Inc. | Controlling therapy based on sleep quality |
| US7387608B2 (en) * | 2004-04-06 | 2008-06-17 | David A Dunlop | Apparatus and method for the treatment of sleep related disorders |
| US7596413B2 (en) * | 2004-06-08 | 2009-09-29 | Cardiac Pacemakers, Inc. | Coordinated therapy for disordered breathing including baroreflex modulation |
| CA2578684C (en) | 2004-06-24 | 2017-07-25 | Vivometrics, Inc. | Systems and methods for monitoring cough |
| US7486993B2 (en) * | 2004-08-05 | 2009-02-03 | Neurotone Systems, Inc. | Brain stimulation method and device |
| US20060039866A1 (en) * | 2004-08-20 | 2006-02-23 | Cypress Bioscience, Inc. | Method for treating sleep-related breathing disorders |
| US20060058852A1 (en) * | 2004-09-10 | 2006-03-16 | Steve Koh | Multi-variable feedback control of stimulation for inspiratory facilitation |
| US7603174B2 (en) * | 2004-10-21 | 2009-10-13 | Advanced Neuromodulation Systems, Inc. | Stimulation of the amygdalohippocampal complex to treat neurological conditions |
| WO2006050523A1 (en) | 2004-11-02 | 2006-05-11 | Medtronic, Inc. | Apparatus for data retention in an implantable medical device |
| EP2213331A3 (en) * | 2004-11-18 | 2014-08-06 | Cardiac Pacemakers, Inc. | Cardiac rhythm management device with neural sensor |
| US7551958B2 (en) | 2005-05-24 | 2009-06-23 | Cardiac Pacemakers, Inc. | Safety control system for implantable neural stimulator |
| US8036750B2 (en) * | 2005-06-13 | 2011-10-11 | Cardiac Pacemakers, Inc. | System for neural control of respiration |
| US8050765B2 (en) | 2006-08-30 | 2011-11-01 | Cardiac Pacemakers, Inc. | Method and apparatus for controlling neural stimulation during disordered breathing |
| US8121692B2 (en) | 2006-08-30 | 2012-02-21 | Cardiac Pacemakers, Inc. | Method and apparatus for neural stimulation with respiratory feedback |
| AU2012200589B2 (en) | 2006-08-30 | 2013-03-14 | Cardiac Pacemakers, Inc. | System for neural stimulation with respiratory feedback |
| US8504154B2 (en) | 2009-03-30 | 2013-08-06 | Medtronic, Inc. | Physiological signal amplifier with voltage protection and fast signal recovery |
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2010502276A (ja) | 2010-01-28 |
| AU2007290623A1 (en) | 2008-03-06 |
| US20080058873A1 (en) | 2008-03-06 |
| WO2008027297A3 (en) | 2008-06-05 |
| US8050765B2 (en) | 2011-11-01 |
| US9216291B2 (en) | 2015-12-22 |
| WO2008027297A2 (en) | 2008-03-06 |
| AU2007290623B2 (en) | 2011-06-09 |
| US20130268030A1 (en) | 2013-10-10 |
| US8483834B2 (en) | 2013-07-09 |
| EP2066400A2 (en) | 2009-06-10 |
| US20120046709A1 (en) | 2012-02-23 |
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