AU2007290623B2 - System for neural stimulation during disordered breathing - Google Patents
System for neural stimulation during disordered breathing Download PDFInfo
- Publication number
- AU2007290623B2 AU2007290623B2 AU2007290623A AU2007290623A AU2007290623B2 AU 2007290623 B2 AU2007290623 B2 AU 2007290623B2 AU 2007290623 A AU2007290623 A AU 2007290623A AU 2007290623 A AU2007290623 A AU 2007290623A AU 2007290623 B2 AU2007290623 B2 AU 2007290623B2
- Authority
- AU
- Australia
- Prior art keywords
- respiratory
- therapy
- apnea
- neural stimulation
- delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 230000000638 stimulation Effects 0.000 title claims description 341
- 230000001537 neural effect Effects 0.000 title claims description 219
- 230000029058 respiratory gaseous exchange Effects 0.000 title claims description 69
- 230000000241 respiratory effect Effects 0.000 claims description 209
- 208000023504 respiratory system disease Diseases 0.000 claims description 181
- 238000002560 therapeutic procedure Methods 0.000 claims description 135
- 238000012384 transportation and delivery Methods 0.000 claims description 108
- 230000008518 non respiratory effect Effects 0.000 claims description 85
- 208000008784 apnea Diseases 0.000 claims description 73
- 238000001514 detection method Methods 0.000 claims description 65
- 230000004044 response Effects 0.000 claims description 49
- 238000000034 method Methods 0.000 claims description 44
- 238000002644 respiratory therapy Methods 0.000 claims description 36
- 230000000747 cardiac effect Effects 0.000 claims description 31
- 239000003169 respiratory stimulant agent Substances 0.000 claims description 23
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 9
- 208000035475 disorder Diseases 0.000 claims description 9
- 230000000116 mitigating effect Effects 0.000 claims description 9
- 238000012544 monitoring process Methods 0.000 claims description 4
- 201000002859 sleep apnea Diseases 0.000 claims description 3
- 206010021079 Hypopnoea Diseases 0.000 description 24
- 208000000059 Dyspnea Diseases 0.000 description 21
- 206010013975 Dyspnoeas Diseases 0.000 description 21
- 230000007384 vagal nerve stimulation Effects 0.000 description 21
- 230000036387 respiratory rate Effects 0.000 description 18
- 238000012545 processing Methods 0.000 description 17
- 238000010586 diagram Methods 0.000 description 14
- 210000005036 nerve Anatomy 0.000 description 13
- 206010019280 Heart failures Diseases 0.000 description 11
- 230000035790 physiological processes and functions Effects 0.000 description 11
- 230000000694 effects Effects 0.000 description 10
- 238000009423 ventilation Methods 0.000 description 10
- 230000006870 function Effects 0.000 description 9
- 230000036772 blood pressure Effects 0.000 description 7
- 230000002159 abnormal effect Effects 0.000 description 6
- 208000019622 heart disease Diseases 0.000 description 5
- 230000000004 hemodynamic effect Effects 0.000 description 5
- 210000000653 nervous system Anatomy 0.000 description 5
- 210000001186 vagus nerve Anatomy 0.000 description 5
- 208000020446 Cardiac disease Diseases 0.000 description 4
- 210000003403 autonomic nervous system Anatomy 0.000 description 4
- 230000007423 decrease Effects 0.000 description 4
- 230000002889 sympathetic effect Effects 0.000 description 4
- 230000001515 vagal effect Effects 0.000 description 4
- 208000033774 Ventricular Remodeling Diseases 0.000 description 3
- 230000002411 adverse Effects 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 238000007634 remodeling Methods 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- 208000034423 Delivery Diseases 0.000 description 2
- 238000011374 additional therapy Methods 0.000 description 2
- 206010003119 arrhythmia Diseases 0.000 description 2
- 230000006793 arrhythmia Effects 0.000 description 2
- 230000004872 arterial blood pressure Effects 0.000 description 2
- 210000000467 autonomic pathway Anatomy 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 230000008602 contraction Effects 0.000 description 2
- 238000007726 management method Methods 0.000 description 2
- 230000002107 myocardial effect Effects 0.000 description 2
- 210000005037 parasympathetic nerve Anatomy 0.000 description 2
- 210000001002 parasympathetic nervous system Anatomy 0.000 description 2
- 210000001147 pulmonary artery Anatomy 0.000 description 2
- 230000001360 synchronised effect Effects 0.000 description 2
- 206010007559 Cardiac failure congestive Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 230000036982 action potential Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 238000009125 cardiac resynchronization therapy Methods 0.000 description 1
- 238000013194 cardioversion Methods 0.000 description 1
- 238000002659 cell therapy Methods 0.000 description 1
- 230000002060 circadian Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 230000003205 diastolic effect Effects 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000001415 gene therapy Methods 0.000 description 1
- 230000004217 heart function Effects 0.000 description 1
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- 208000027866 inflammatory disease Diseases 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 230000003767 neural control Effects 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Measuring devices for evaluating the respiratory organs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4029—Detecting, measuring or recording for evaluating the nervous system for evaluating the peripheral nervous systems
- A61B5/4035—Evaluating the autonomic nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4806—Sleep evaluation
- A61B5/4818—Sleep apnoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3601—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of respiratory organs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36135—Control systems using physiological parameters
- A61N1/3614—Control systems using physiological parameters based on impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Measuring devices for evaluating the respiratory organs
- A61B5/0816—Measuring devices for examining respiratory frequency
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Neurology (AREA)
- Physiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Electrotherapy Devices (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/468,603 US8050765B2 (en) | 2006-08-30 | 2006-08-30 | Method and apparatus for controlling neural stimulation during disordered breathing |
| US11/468,603 | 2006-08-30 | ||
| PCT/US2007/018697 WO2008027297A2 (en) | 2006-08-30 | 2007-08-24 | System for neural stimulation during disordered breathing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2007290623A1 AU2007290623A1 (en) | 2008-03-06 |
| AU2007290623B2 true AU2007290623B2 (en) | 2011-06-09 |
Family
ID=39120704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2007290623A Ceased AU2007290623B2 (en) | 2006-08-30 | 2007-08-24 | System for neural stimulation during disordered breathing |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US8050765B2 (enExample) |
| EP (1) | EP2066400A2 (enExample) |
| JP (1) | JP5231418B2 (enExample) |
| AU (1) | AU2007290623B2 (enExample) |
| WO (1) | WO2008027297A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8923971B2 (en) | 2006-08-30 | 2014-12-30 | Cardiac Pacemakers, Inc. | Method and apparatus for neural stimulation with respiratory feedback |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8050765B2 (en) | 2006-08-30 | 2011-11-01 | Cardiac Pacemakers, Inc. | Method and apparatus for controlling neural stimulation during disordered breathing |
| CA3000408C (en) | 2007-01-29 | 2024-04-02 | Lungpacer Medical Inc. | Transvascular nerve stimulation apparatus and methods |
| US9486152B2 (en) | 2007-03-09 | 2016-11-08 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Respiratory-based control of medical procedure |
| WO2009137189A1 (en) * | 2008-05-07 | 2009-11-12 | Cardiac Pacemakers, Inc. | System and method for detection of pulmonary embolism |
| US8229566B2 (en) * | 2008-06-25 | 2012-07-24 | Sheng Li | Method and apparatus of breathing-controlled electrical stimulation for skeletal muscles |
| US8844525B2 (en) * | 2008-07-25 | 2014-09-30 | Resmed Limited | Method and apparatus for detecting and treating heart failure |
| US8509919B2 (en) | 2010-06-03 | 2013-08-13 | Cardiac Pacemakers, Inc. | Spatially selective vagus nerve stimulation |
| US9042981B2 (en) | 2010-06-03 | 2015-05-26 | Cardiac Pacemakers, Inc. | Vagus nerve stimulation with target effects controlled by adjusting temporal parameters |
| US8942819B2 (en) | 2010-06-16 | 2015-01-27 | Cardiac Pacemakers, Inc. | Automatic neural stimulation titration sweep |
| US9089267B2 (en) | 2010-06-18 | 2015-07-28 | Cardiac Pacemakers, Inc. | Methods and apparatus for adjusting neurostimulation intensity using evoked responses |
| WO2013023218A1 (en) | 2011-08-11 | 2013-02-14 | Inspire Medical Systems, Inc. | System for selecting a stimulation protocol based on sensed respiratory effort |
| IN2014MN01970A (enExample) | 2012-03-05 | 2015-07-03 | Univ Fraser Simon | |
| EP4233953A3 (en) | 2012-06-21 | 2023-11-01 | Lungpacer Medical Inc. | Transvascular diaphragm pacing systems |
| EP3071285B1 (en) | 2013-11-22 | 2020-06-03 | Lungpacer Medical Inc. | Apparatus for assisted breathing by transvascular nerve stimulation |
| CN105916549B (zh) | 2014-01-21 | 2019-04-23 | 隆佩瑟尔医疗公司 | 用于优化多电极神经起搏的系统及相关方法 |
| EP2904964B1 (fr) * | 2014-02-11 | 2019-10-02 | Sorin CRM SAS | Ensemble avec dispositif médical à stimulation kinesthésique pour l'évaluation non invasive de l'équilibre sympathovagal d'un patient. |
| US10898709B2 (en) | 2015-03-19 | 2021-01-26 | Inspire Medical Systems, Inc. | Stimulation for treating sleep disordered breathing |
| US20180325468A1 (en) * | 2015-08-31 | 2018-11-15 | Eric Helfenbein | Monitoring device with multi-parameter hyperventilation alert |
| CN110325110B (zh) | 2016-11-10 | 2022-08-09 | 纽约州立大学研究基金会 | 用于气道阻塞的系统、方法和生物标记 |
| US10293164B2 (en) | 2017-05-26 | 2019-05-21 | Lungpacer Medical Inc. | Apparatus and methods for assisted breathing by transvascular nerve stimulation |
| EP4115942B1 (en) | 2017-06-30 | 2024-04-24 | Lungpacer Medical Inc. | System for prevention, moderation, and/or treatment of cognitive injury |
| US10195429B1 (en) | 2017-08-02 | 2019-02-05 | Lungpacer Medical Inc. | Systems and methods for intravascular catheter positioning and/or nerve stimulation |
| US10940308B2 (en) | 2017-08-04 | 2021-03-09 | Lungpacer Medical Inc. | Systems and methods for trans-esophageal sympathetic ganglion recruitment |
| US20190175908A1 (en) | 2017-12-11 | 2019-06-13 | Lungpacer Medical Inc. | Systems and methods for strengthening a respiratory muscle |
| WO2020097331A1 (en) | 2018-11-08 | 2020-05-14 | Lungpacer Medical Inc. | Stimulation systems and related user interfaces |
| WO2020123704A1 (en) | 2018-12-13 | 2020-06-18 | Livanova Usa, Inc. | Neuromodulation therapy for auto-immune and inflammatory disorders |
| JP7677631B2 (ja) * | 2019-05-16 | 2025-05-15 | ラングペーサー メディカル インコーポレイテッド | 検知及び刺激のためのシステム及び方法 |
| WO2020252037A1 (en) | 2019-06-12 | 2020-12-17 | Lungpacer Medical Inc. | Circuitry for medical stimulation systems |
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| WO2006127366A1 (en) * | 2005-05-24 | 2006-11-30 | Cardiac Pacemakers, Inc. | Safety control system for implantable neural stimulator |
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2008027297A2 (en) | 2008-03-06 |
| JP2010502276A (ja) | 2010-01-28 |
| US20080058873A1 (en) | 2008-03-06 |
| AU2007290623A1 (en) | 2008-03-06 |
| US9216291B2 (en) | 2015-12-22 |
| JP5231418B2 (ja) | 2013-07-10 |
| WO2008027297A3 (en) | 2008-06-05 |
| US20120046709A1 (en) | 2012-02-23 |
| US20130268030A1 (en) | 2013-10-10 |
| US8483834B2 (en) | 2013-07-09 |
| EP2066400A2 (en) | 2009-06-10 |
| US8050765B2 (en) | 2011-11-01 |
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