JP5228203B2 - Pest control agents and methods of use - Google Patents

Pest control agents and methods of use Download PDF

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JP5228203B2
JP5228203B2 JP2010259477A JP2010259477A JP5228203B2 JP 5228203 B2 JP5228203 B2 JP 5228203B2 JP 2010259477 A JP2010259477 A JP 2010259477A JP 2010259477 A JP2010259477 A JP 2010259477A JP 5228203 B2 JP5228203 B2 JP 5228203B2
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大介 田中
わこ 上村
愛咲 加藤
絵梨 伊藤
沙織 切明畑
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大介 田中
わこ 上村
愛咲 加藤
絵梨 伊藤
沙織 切明畑
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本発明は、環形動物個体群および扁平動物個体群防御剤に関する技術を提供する。より詳細には、サリチル酸誘導体(サリチル酸2−ヒドロキシエチル、サリチル酸メチル、サリチル酸等)からなる群から選ばれる化合物の1種又は2種以上を有効成分として含有し、その他にテルペン類またはバニロイド類を含めてもよい混合物からなる環形動物個体群お よび扁平動物個体群防除剤とその利用方法を提供する。The present invention provides techniques relating to annelid populations and flat animal population protection agents. More specifically, it contains one or more compounds selected from the group consisting of salicylic acid derivatives (2-hydroxyethyl salicylate, methyl salicylate, salicylic acid, etc.) as active ingredients, and in addition, terpenes or vanilloids are included. Annelida populations consisting also be mixture Contact called squamous animal populations control agent provides its use.

ヒルを代表とした環形動物などの有害生物は、里山の荒廃に取り組む森林管理者を吸血し被害をもたらす。
現在の防除方法には、市販の虫除けスプレー、N,N−ジエチル−m−トルアミド(DEET)、木酢液、塩、石けん、アニオン系環形動物忌避剤がある。
Pests such as annelids represented by hills suck blood and cause damage to forest managers working on the devastation of satoyama.
Current control methods include commercially available insect repellent sprays, N, N-diethyl-m-toluamide (DEET), wood vinegar, salt, soap, anionic ring-shaped animal repellents.

しかし、木酢液や塩よりも高い忌避効果と実用性のあるDEET等は、米国小児科学会では子供用虫除け薬のDEET含有量を極端に下げるように指導している(非特許文献1)。また、手についた場合は石けんと水でよく洗うなど、使用上の注意が多く肌に触れて良いものとは言えない。However, DEET, which has higher repellent effect and practicality than wood vinegar and salt, is instructed by the American Academy of Pediatrics to extremely reduce the DEET content of insect repellents for children (Non-patent Document 1). Also, if you touch your hands, wash them with soap and water, and you may not be able to touch your skin.

そこで、前述の殺虫剤よりも安全性が高く、環境負担が低い有害生物忌避剤の有効成分として木酢液やシトロネラ油が挙げられるが、その忌避効果を確認するには大量の散布を必要とする(非特許文献2)。Therefore, wood vinegar and citronella oil are listed as active ingredients for pest repellents that are safer and less environmentally burdensome than the insecticides mentioned above, but a large amount of spraying is required to confirm their repellent effects. (Non-patent document 2).

AAP News,Follow Safety Precautions When Using DEET on Children,June 2003AAP News, Follow Safety Prescriptions When Using DEET on Children, June 2003

神奈川県ヤマビル対策共同研究報告書、神奈川県ヤマビル対策共同推進会議事務局、平成21年3月Kanagawa Prefecture Yamaville Countermeasures Joint Research Report, Kanagawa Prefecture Yamaville Countermeasures Promotion Council Secretariat, March 2009

本発明は、持続性、安定性に優れ、優れた防除効果を示し、使用形態が限定されず、天然物由来のように安全性(特に人体に対する安全性が高い)があり、且つ環境負担の軽減が期待できる環形動物個体群および扁平動物個体群を対象とした防除剤とその使用方法を提供すること。The present invention is excellent in sustainability and stability, exhibits an excellent control effect, is not limited in use form, has safety (particularly high safety to the human body) as derived from natural products, and has an environmental burden. To provide a control agent for an annelid population and a flat animal population that can be expected to be reduced, and a method for using the same.

本発明の環形動物個体群および扁平動物個体群防除剤は、サリチル酸2−ヒドロキシエチルあるいはその類似化合物からなる群から選ばれる化合物の1種又は2種以上を有効成分として含有することを特徴とする。また、L−メントールを代表とするテルペン類あるいはバニリンを代表とするバニロイド類を含めることでより高い効果が得られる。環形動物 個体群および扁平動物個体群防除用組成物を、防除を所望する物体(例えば、履物、衣服、住宅外壁等)に噴霧、塗布、散布あるいは環形動物個体群および扁平動物個体群に直接、接触させることにより、上記目的である環形動物個体群および扁平動物個体群防除効果を達成できる。The annelid population and flat animal population control agent of the present invention are characterized by containing one or more compounds selected from the group consisting of 2-hydroxyethyl salicylate or a similar compound as an active ingredient. . Moreover, a higher effect can be obtained by including terpenes typified by L-menthol or vanilloids typified by vanillin. The annelids populations and flat animal populations composition for controlling an object to desired control (e.g., footwear, clothing, housing outer wall, etc.) sprayed, coated, directly to the distribution or annelids populations and flat animal populations, By bringing them into contact with each other, it is possible to achieve the above-mentioned purpose of controlling the annulus animal population and the flat animal population .

少なくとも1種類以上のサリチル酸誘導体あるいはその類似化合物を有効成分とした環形 動物個体群および扁平動物個体群防除剤を提供する。さらに、テルペン類あるいはバニロ イド類からなる天然有機化合物を混合することでより高い環形動物個体群および扁平動物 個体群防除効果を得ることが出来る。本発明による防除剤は忌避効果のみならず駆除効果をも有する。また、本発明による防除剤は、薬剤の保持力が高いため、下草の多い山林での作業や雨中等にも効果を発揮する。また、その簡便な利用方法を提供し、小児や身体に障害のある人でも容易に使用可能とすることである。Providing at least one or more salicylic acid derivatives or annelids populations and flat animal populations control agent that the analogous compound as an active ingredient. Furthermore, terpenes or Baniro id such natural organic compound higher than by mixing annelid populations and flat animal populations control effect can be obtained consisting of. The control agent according to the present invention has a repellent effect as well as a repellent effect. In addition, since the control agent according to the present invention has a high drug holding power, it is effective in work in a forest with a lot of undergrowth and in the rain. In addition, it is intended to provide a simple usage method that can be easily used by children and persons with physical disabilities.

本発明における環形動物個体群および扁平動物個体群防除剤は、サリチル酸誘導体(サリチル酸2−ヒドロキシエチル、サリチル酸メチル、サリチル酸等)からなる群から選ばれる化合物の1種又は2種以上を有効成分として含有し、その他にテルペン類またはバニロ イド類を含めてもよい混合物からなる液体状または固体状の物質である。The annelid population and flat animal population control agent according to the present invention contain, as an active ingredient, one or more compounds selected from the group consisting of salicylic acid derivatives (2-hydroxyethyl salicylate, methyl salicylate, salicylic acid, etc.). and a liquid or solid substances consisting other terpenes or Baniro id compounds may include a mixture.

本発明において効果が認められたサリチル酸誘導体は、サリチル酸、サリチル酸メチル、サリチル酸エチル、およびサリチル酸2−ヒドロキシエチルである。中でもサリチル酸2−ヒドロキシエチルが最も高い効果が得られた。しかし、上記化合物に限定するものではない。Salicylic acid derivatives that have been found to be effective in the present invention are salicylic acid, methyl salicylate, ethyl salicylate, and 2-hydroxyethyl salicylate. Of these, 2-hydroxyethyl salicylate was most effective. However, it is not limited to the above compounds.

本発明におけるテルペン類の利用例としては、メントール、メンタンが挙げられるが、これらの化合物に限定するものではない。Examples of the use of terpenes in the present invention include menthol and menthane, but are not limited to these compounds.

本発明におけるバニロイド類の利用例としては、バニリンが挙げられるが、これらの化合物に限定するものではない。Examples of the use of vanilloids in the present invention include vanillin, but are not limited to these compounds.

テルペン類の由来としては特にハッカ油が有効であったが、これに限定するものではない。Although mint oil was particularly effective as the origin of terpenes, it is not limited to this.

バニロイド類の由来としてはバニラ抽出物が有効であったが、これに限定するものではない。 Although vanilla extract was effective as the origin of vanilloids, it is not limited to this.

本発明における環形動物個体群および扁平動物個体群防除剤は特に加工することなく防除効果を示すが、溶液状にすることでより高い利便性を示すことができる。The annulus animal population and the flat animal population control agent in the present invention exhibit a control effect without any particular processing, but higher convenience can be shown by making the solution.

溶液状にするための方法として、有機溶媒への溶解や、界面活性剤による乳化、またはマイクロカプセルへの包埋による水への溶解が有効である。有機溶媒としてはエタノールなど身体に有害でないものが好ましい。As a method for forming a solution, dissolution in an organic solvent, emulsification with a surfactant, or dissolution in water by embedding in a microcapsule is effective. As the organic solvent, ethanol and the like which are not harmful to the body are preferable.

本発明における溶液状の環形動物個体群および扁平動物個体群防除剤は、噴射用圧縮ガスと共に噴射ノズル及びバルブ付きのスプレー用容器に封入することで、簡便に噴霧することが可能である。この環形動物個体群および扁平動物個体群防除剤は防除効果を噴霧によって失うことはない。The solution-like annulus animal population and flat animal population control agent in the present invention can be easily sprayed by enclosing them in a spray container with a spray nozzle and a valve together with a compressed gas for spraying. This annelid and flat animal population control agent does not lose its control effect by spraying.

本発明における環形動物個体群および扁平動物個体群防除剤は紙、布、不織布、合成樹脂シートなど吸収性物体あるいは、ゼラチンや寒天などゲル状物質への塗布、吹き付け、注入、浸漬、練り込み、添加および石鹸や蝋など固形油脂への混合、練り込みなどにより、その防除成分を徐放することが可能である。
この方法により防除効果を簡便に長期間にわたり持続させることが可能である。
Annular animal populations and flat animal population control agents in the present invention are applied to absorptive objects such as paper, cloth, non-woven fabric, synthetic resin sheet, or gel-like substances such as gelatin and agar, sprayed, poured, immersed, kneaded, The control component can be released slowly by addition, mixing with a solid oil such as soap or wax, and kneading.
By this method, the control effect can be easily maintained for a long time.

本発明における環形動物個体群および扁平動物個体群防除剤は、ヒトをはじめとする動物や植物に対して有害でなく、天然由来成分を主とするため環境負荷も少ない。これらのことから、人体あるいは動物表面または履物、衣服、機械、網戸、ガラス、床、壁、あらゆる生活区域への適用が可能である。また成分が比較的長期間にわたり安定であり、かつ薬剤の保持力が高いため、下草の多い山林での作業や雨中等にも効果を発揮する。The annulus animal population and the flat animal population control agent in the present invention are not harmful to animals and plants including humans, and are mainly environmentally-derived components and therefore have little environmental impact. From these, it can be applied to human or animal surfaces or footwear, clothes, machines, screen doors, glass, floors, walls, and any living area. In addition, since the ingredients are stable for a relatively long period of time and have high drug retention, they are also effective in working in forests with a lot of undergrowth and in the rain.

本発明における環形動物個体群および扁平動物個体群防除剤は、直接環形動物個体群およ び扁平動物個体群に接触させることでも防除効果を発揮する。
例えばスプレータイプの環形動物個体群および扁平動物個体群防除剤を直接吹きかけ防除効果が得られる。
Annelida populations and flat animal populations control agent in the present invention also exhibits control effect is contacted directly annelids populations Oyo fine flat animal populations.
For example, a spray-type annelid population and a flat animal population control agent are directly sprayed to obtain a control effect.

実験方法はA6サイズのコピー用紙の中心に直径8.6センチメートルの円を鉛筆で書き、その円の外に試薬を塗る。円の中にヤマビルを置き、その円の中からヤマビルが出られるかどうか忌避率を調べた。試薬を溶解するものは100%エタノールとする。In the experiment method, a circle of 8.6 cm in diameter is written with a pencil in the center of A6 size copy paper, and a reagent is applied outside the circle. I placed a Yamabiru in the circle, and examined the repellent rate to see if it could come out of the circle. The reagent is dissolved in 100% ethanol.

サリチル酸2−ヒドロキシエチルを3、5、10、15、30、40、50、100mg/1mlの濃度で円の外に塗り実験を行った。その結果、忌避率は0、30、80、100、100、100、100および100%であった。An experiment was conducted in which 2-hydroxyethyl salicylate was applied outside the circle at concentrations of 3, 5, 10, 15, 30, 40, 50, and 100 mg / 1 ml. As a result, the repelling rate was 0, 30, 80, 100, 100, 100, 100 and 100%.

テルペン類(L−メントール)を3、5、10、15、30、40、50、100mg/1mlの濃度で円の外に塗り実験を行った。その結果、忌避率は0、0、0、10、20、50、100および100%であった。Terpenes (L-menthol) were applied to the outside of the circle at concentrations of 3, 5, 10, 15, 30, 40, 50, and 100 mg / 1 ml, and experiments were conducted. As a result, the repelling rate was 0, 0, 0, 10, 20, 50, 100 and 100%.

バニロイド類(バニリン)を3、5、7.5、10、15、30、40mg/1mlの濃度で円の外に塗り実験を行った。その結果、ヤマビルの忌避率は0、10、50、80、80、80および100%であった。 Vanilloids (vanillin) were applied to the outside of the circle at concentrations of 3, 5, 7.5, 10, 15, 30, and 40 mg / 1 ml. As a result, the repellent rate of Yamavir was 0, 10, 50, 80, 80, 80 and 100%.

表1は、サリチル酸2−ヒドロキシエチル、サリチル酸メチル、サリチル酸、アセチルサリチル酸、L−メントール、バニリンおよびカプサイシンの濃度と忌避率の関係を示す表である。Table 1 is a table showing the relationship between the concentration of 2-hydroxyethyl salicylate, methyl salicylate, salicylic acid, acetylsalicylic acid, L-menthol, vanillin and capsaicin and the repellent rate.

Figure 0005228203
Figure 0005228203

サリチル酸2−ヒドロキシエチルを5mg/1mlとバニリンを7.5mg/1mlの濃度で円の外に塗り実験を行った。忌避率は100%であった。また、成分量を増加した場合も100%であった。Experiments were conducted by applying 2-hydroxyethyl salicylate outside the circle at a concentration of 5 mg / 1 ml and vanillin 7.5 mg / 1 ml. The repellent rate was 100%. Moreover, it was 100% when the amount of components was increased.

サリチル酸2−ヒドロキシエチルを5mg/1mlとL−メントール40mg/1mlの濃度で円の外に塗り実験を行った。忌避率は100%であった。また成分量を増加した場合も100%であった。The experiment was carried out by applying 2-hydroxyethyl salicylate outside the circle at a concentration of 5 mg / 1 ml and L-menthol 40 mg / 1 ml. The repellent rate was 100%. Moreover, it was 100% when the amount of ingredients was increased.

表2は、サリチル酸2−ヒドロキシエチル、L−メントール、バニリンおよびカプサイシンの濃度と忌避率の関係を示す表である。Table 2 is a table showing the relationship between the concentration of 2-hydroxyethyl salicylate, L-menthol, vanillin and capsaicin and the repellent rate.

Figure 0005228203
Figure 0005228203

(比較例1)
エタノール100%を円の外に塗り実験を行った。忌避率は0%であった。よってエタノールを試薬の溶解する有機溶媒として使用する。
(Comparative Example 1)
An experiment was performed in which 100% ethanol was applied outside the circle. The repellent rate was 0%. Therefore, ethanol is used as the organic solvent in which the reagent is dissolved.

Claims (11)

サリチル酸誘導体からなる群から選ばれる化合物の1種又は2種以上を有効成分として含有することを特徴とする環形動物個体群および扁平動物個体群防除剤。An annulus animal population and a flat animal population control agent comprising one or more compounds selected from the group consisting of salicylic acid derivatives as active ingredients. 請求項1に記載の環形動物個体群および扁平動物個体群防御剤にテルペン類またはバニロ イド類を含む請求項1に記載の環形動物個体群および扁平動物個体群防除剤。 Annelida populations and flat animal populations control agent according to claim 1 comprising a terpene or Baniro Id acids in annelids populations and flat animal populations protective agent according to claim 1. サリチル酸メチルを代表としたサリチル酸誘導体の由来として植物由来成分を含んで成る請求項1に記載の環形動物個体群および扁平動物個体群防除剤。The annelid population and flat animal population control agent according to claim 1, comprising a plant-derived component as a source of a salicylic acid derivative represented by methyl salicylate. L−メントールを代表としたテルペン類の由来としてハッカ油を含んで成る請求項1に記載の環形動物個体群および扁平動物個体群防除剤。 The annelid population and flat animal population control agent according to claim 1, comprising mint oil derived from terpenes typified by L-menthol . バニリンを代表としたバニロイド類を含んで成る請求項1に記載の組成物。The composition according to claim 1, comprising vanilloids typified by vanillin. 揮発性で臭気を出す1種又はそれ以上の液状又は固体状の混合物を有機溶剤中に分散した分散液であることを特徴とする請求項1〜5のいずれかに記載の環形動物個体群および扁 平動物個体群防除剤。An annelid population according to any one of claims 1 to 5, which is a dispersion in which one or more liquid or solid mixtures that are volatile and emit odor are dispersed in an organic solvent. Bian flat animal population control agent. 揮発性で臭気を出す1種又はそれ以上の液状又は固体状の混合物をマイクロカプセル粒子に包埋あるいは界面活性剤等による乳化などの溶解補助により溶解した水溶液の形であることを特徴とする請求項1〜5のいずれかに記載の環形動物個体群および扁平動物個体群防除剤。One or more liquid or solid mixtures that are volatile and emit odor are in the form of an aqueous solution in which they are embedded in microcapsule particles or dissolved with the aid of dissolution such as emulsification with a surfactant or the like. Item 6. An annulus animal population and a flat animal population control agent according to any one of Items 1 to 5. 請求項1〜5に記載の環形動物個体群および扁平動物個体群防除剤が噴射用圧縮ガスと共に噴射ノズル及びバルブ付きのスプレー用容器に封入されたスプレー剤。The spray agent with which the annulus animal population and flat animal population control agent of Claims 1-5 were enclosed with the spray nozzle and the spray container with a valve with the compressed gas for injection. 請求項1〜5に記載の環形動物個体群および扁平動物個体群防除剤成分の徐放を目的に含浸した物体から成る環形動物個体群および扁平動物個体群防除剤。Sustained release annelids populations and flat animal populations control agent consisting of impregnated body for the purpose of annelids populations and flat animal populations control agent component of claim 1 to 5. 人体あるいは動物表面または履物、衣服、機械、網戸、ガラス、床、壁に塗布、噴霧、散布し、用いることを特徴とする請求項1〜5に記載の環形動物個体群および扁平動物個体 防除剤。Human or animal surface or footwear, clothing, machine, screen doors, glass, floors, walls coating, spraying, sprinkling, annelids populations and flat animal populations control of claim 1, wherein the use Agent. 請求項1〜5に記載の防除剤を環形動物個体群および扁平動物個体群に直接接触させることによる防除方法。The control method by making the control agent of Claims 1-5 contact an annular animal population and a flat animal population directly.
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SE0203650D0 (en) * 2002-12-06 2002-12-06 Organox Ab Pest controlling system
BRPI0714350B1 (en) * 2006-07-17 2017-03-07 Tyratech Inc compositions and methods for control of insects

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