JP5219818B2 - 乳癌および卵巣癌の治療薬、検出方法ならびに検出用キット - Google Patents

乳癌および卵巣癌の治療薬、検出方法ならびに検出用キット Download PDF

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JP5219818B2
JP5219818B2 JP2008536470A JP2008536470A JP5219818B2 JP 5219818 B2 JP5219818 B2 JP 5219818B2 JP 2008536470 A JP2008536470 A JP 2008536470A JP 2008536470 A JP2008536470 A JP 2008536470A JP 5219818 B2 JP5219818 B2 JP 5219818B2
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prdm14
gene
expression
expression level
ovarian cancer
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JPWO2008038832A1 (ja
Inventor
実 豊田
隆至 時野
公一 平田
紀子 西川
東生 大村
浩三 今井
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今井浩三
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/7105Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2008536470A 2006-09-27 2007-09-27 乳癌および卵巣癌の治療薬、検出方法ならびに検出用キット Active JP5219818B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2008536470A JP5219818B2 (ja) 2006-09-27 2007-09-27 乳癌および卵巣癌の治療薬、検出方法ならびに検出用キット

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2006263232 2006-09-27
JP2006263232 2006-09-27
PCT/JP2007/069413 WO2008038832A1 (fr) 2006-09-27 2007-09-27 Agent thérapeutique, procédé de détection et kit de détection pour cancer du sein et cancer ovarien
JP2008536470A JP5219818B2 (ja) 2006-09-27 2007-09-27 乳癌および卵巣癌の治療薬、検出方法ならびに検出用キット

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JP2012253108A Division JP5395246B2 (ja) 2006-09-27 2012-11-19 乳癌および卵巣癌の治療薬、検出方法ならびに検出用キット

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JPWO2008038832A1 JPWO2008038832A1 (ja) 2010-04-08
JP5219818B2 true JP5219818B2 (ja) 2013-06-26

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JP2008536470A Active JP5219818B2 (ja) 2006-09-27 2007-09-27 乳癌および卵巣癌の治療薬、検出方法ならびに検出用キット
JP2012253108A Active JP5395246B2 (ja) 2006-09-27 2012-11-19 乳癌および卵巣癌の治療薬、検出方法ならびに検出用キット

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JP (2) JP5219818B2 (enrdf_load_stackoverflow)
WO (1) WO2008038832A1 (enrdf_load_stackoverflow)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6683986B2 (ja) * 2013-07-10 2020-04-22 国立大学法人 東京大学 がん幹細胞分子マーカー
SG10201607303YA (en) 2016-09-01 2018-04-27 Agency Science Tech & Res Antisense oligonucleotides to induce exon skipping
JP6898617B2 (ja) * 2017-09-26 2021-07-07 国立大学法人 東京大学 Prdm14発現を確認する方法
EP3996684A4 (en) * 2019-07-09 2024-06-19 Ariz Precision Medicine, Inc. CANCER TREATMENT USING TARGETED PHARMACEUTICAL SIRNA FORMULATIONS TO DECREASE THE EXPRESSION OF THE PRDM14 PROTEIN
EP4150093A4 (en) 2020-05-14 2024-06-19 Ariz Precision Medicine, Inc. CANCER TREATMENT USING SIRNA TO MODULATE PRDM2/RICE PROTEIN EXPRESSION

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060014173A1 (en) * 2001-07-18 2006-01-19 The Burnham Institute PR/SET-domain containing nucleic acids, polypeptides, antibodies and methods of use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060014173A1 (en) * 2001-07-18 2006-01-19 The Burnham Institute PR/SET-domain containing nucleic acids, polypeptides, antibodies and methods of use

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6012048080; 西川紀子, et al.: '乳癌におけるヒストンメチル化酵素PRDM14遺伝子の発現上昇および遺伝子増幅' 日本癌学会学術総会記事 Vol. 65th, 20060828, p. 154 (#224) *
JPN6012048081; Hu M, et al.: 'Distinct epigenetic changes in the stromal cells of breast cancers' Nature Genetics Vol. 37, No. 8, 200508, p. 899-905 *

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JPWO2008038832A1 (ja) 2010-04-08
JP2013100286A (ja) 2013-05-23
WO2008038832A1 (fr) 2008-04-03
JP5395246B2 (ja) 2014-01-22

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