JP5207969B2 - 巨大環状のキレート化剤によるビオチンジアミノ誘導体およびその複合体 - Google Patents
巨大環状のキレート化剤によるビオチンジアミノ誘導体およびその複合体 Download PDFInfo
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- JP5207969B2 JP5207969B2 JP2008532721A JP2008532721A JP5207969B2 JP 5207969 B2 JP5207969 B2 JP 5207969B2 JP 2008532721 A JP2008532721 A JP 2008532721A JP 2008532721 A JP2008532721 A JP 2008532721A JP 5207969 B2 JP5207969 B2 JP 5207969B2
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0495—Pretargeting
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Polyethers (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05021034 | 2005-09-27 | ||
EP05021034.3 | 2005-09-27 | ||
PCT/EP2006/066440 WO2007039437A1 (en) | 2005-09-27 | 2006-09-18 | Biotin diaminoderivatives and their conjugates with macrocyclic chelating agents |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2009510009A JP2009510009A (ja) | 2009-03-12 |
JP5207969B2 true JP5207969B2 (ja) | 2013-06-12 |
Family
ID=35825361
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008532721A Expired - Fee Related JP5207969B2 (ja) | 2005-09-27 | 2006-09-18 | 巨大環状のキレート化剤によるビオチンジアミノ誘導体およびその複合体 |
Country Status (24)
Country | Link |
---|---|
US (1) | US7816388B2 (zh) |
EP (1) | EP1928508B1 (zh) |
JP (1) | JP5207969B2 (zh) |
KR (1) | KR101301549B1 (zh) |
CN (1) | CN101272809B (zh) |
AR (1) | AR056201A1 (zh) |
AT (1) | ATE447977T1 (zh) |
AU (1) | AU2006298827B2 (zh) |
BR (1) | BRPI0616441B8 (zh) |
CA (1) | CA2621960C (zh) |
CY (1) | CY1109836T1 (zh) |
DE (1) | DE602006010413D1 (zh) |
DK (1) | DK1928508T3 (zh) |
EA (1) | EA200800948A1 (zh) |
ES (1) | ES2335609T3 (zh) |
HK (1) | HK1125036A1 (zh) |
HR (1) | HRP20100071T1 (zh) |
ME (1) | ME01845B (zh) |
PL (1) | PL1928508T3 (zh) |
PT (1) | PT1928508E (zh) |
RS (1) | RS51254B (zh) |
SI (1) | SI1928508T1 (zh) |
TW (1) | TWI381852B (zh) |
WO (1) | WO2007039437A1 (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100543342B1 (ko) * | 2002-06-28 | 2006-01-20 | 한국 한의학 연구원 | 뇌신경세포의 손상을 치료하기 위한 한약재 조성물 |
JP5263805B2 (ja) * | 2007-06-13 | 2013-08-14 | 国立大学法人群馬大学 | 両親媒性の高分子配位子によって安定化された高分子錯体および検査用組成物および医薬組成物 |
GB0922369D0 (en) * | 2009-12-22 | 2010-02-03 | Hammersmith Imanet Ltd | Labelled biotin conjugates |
BR112013009614A2 (pt) * | 2010-10-22 | 2016-07-19 | Centre Nat Rech Scient | conjugados de pochoxime úteis para o tratamento de patologias relacionadas à hsp90 |
WO2023240135A2 (en) | 2022-06-07 | 2023-12-14 | Actinium Pharmaceuticals, Inc. | Bifunctional chelators and conjugates |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5283342A (en) | 1992-06-09 | 1994-02-01 | Neorx Corporation | Biotinylated small molecules |
EP1138334A3 (en) | 1992-06-09 | 2002-04-03 | Neorx Corporation | Pretargeting methods and compounds |
US5911969A (en) * | 1992-06-09 | 1999-06-15 | Neorx Corporation | Pretargeting protocols for enhanced localization of active agents to target sites |
US6120768A (en) * | 1993-05-17 | 2000-09-19 | Immunomedics, Inc. | Dota-biotin derivatives |
US5955605A (en) | 1995-02-21 | 1999-09-21 | Neorx Corporation | Biotinidase resistant biotin-DOTA conjugates |
ITRM20010079A1 (it) * | 2001-02-16 | 2002-08-16 | Sigma Tau Ind Farmaceuti | Amminoderivati della biotina e loro coniugati con chelanti macrociclici. |
-
2006
- 2006-09-15 TW TW095134322A patent/TWI381852B/zh not_active IP Right Cessation
- 2006-09-18 PT PT06793583T patent/PT1928508E/pt unknown
- 2006-09-18 JP JP2008532721A patent/JP5207969B2/ja not_active Expired - Fee Related
- 2006-09-18 AU AU2006298827A patent/AU2006298827B2/en not_active Ceased
- 2006-09-18 EP EP06793583A patent/EP1928508B1/en active Active
- 2006-09-18 RS RSP-2010/0031A patent/RS51254B/sr unknown
- 2006-09-18 PL PL06793583T patent/PL1928508T3/pl unknown
- 2006-09-18 ES ES06793583T patent/ES2335609T3/es active Active
- 2006-09-18 CA CA2621960A patent/CA2621960C/en not_active Expired - Fee Related
- 2006-09-18 AT AT06793583T patent/ATE447977T1/de active
- 2006-09-18 ME MEP-2010-31A patent/ME01845B/me unknown
- 2006-09-18 CN CN2006800356289A patent/CN101272809B/zh not_active Expired - Fee Related
- 2006-09-18 WO PCT/EP2006/066440 patent/WO2007039437A1/en active Application Filing
- 2006-09-18 DE DE602006010413T patent/DE602006010413D1/de active Active
- 2006-09-18 EA EA200800948A patent/EA200800948A1/ru not_active IP Right Cessation
- 2006-09-18 DK DK06793583.3T patent/DK1928508T3/da active
- 2006-09-18 US US12/065,833 patent/US7816388B2/en not_active Expired - Fee Related
- 2006-09-18 KR KR1020087006421A patent/KR101301549B1/ko active IP Right Grant
- 2006-09-18 BR BRPI0616441A patent/BRPI0616441B8/pt not_active IP Right Cessation
- 2006-09-18 SI SI200630557T patent/SI1928508T1/sl unknown
- 2006-09-26 AR ARP060104193A patent/AR056201A1/es unknown
-
2009
- 2009-03-23 HK HK09102783.8A patent/HK1125036A1/xx not_active IP Right Cessation
-
2010
- 2010-02-02 CY CY20101100098T patent/CY1109836T1/el unknown
- 2010-02-08 HR HR20100071T patent/HRP20100071T1/hr unknown
Also Published As
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JP4236282B2 (ja) | 部位特異的ターゲッティング用の放射性標識ペプチド組成物 | |
US8044081B2 (en) | Aminoderivative of biotin and their conjugates with macrocyclic chelating agents | |
JP5207969B2 (ja) | 巨大環状のキレート化剤によるビオチンジアミノ誘導体およびその複合体 | |
AU2002237517A1 (en) | Biotin-derivatives and their conjugates with chelating agents | |
WO2021175147A1 (zh) | 前列腺特异性膜抗原结合配体偶联物及其应用 | |
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