JP5146990B2 - Medicine container and method of using the container - Google Patents

Description

  The present invention relates to a cylindrical or bag-like container that contains a solid dialysis agent or a liquid dialysis agent that is mainly used in the preparation of a dialysis solution used in, for example, artificial dialysis.

  Since the conventional problem regarding this kind of bag-like container is described in patent document 1, the description is cited. That is, “the bag-type dialysis agent storage container is formed into a bag body with a flexible sheet material in the same manner as the container for the drip solution, so that the bulkiness after use can be reduced. However, since dialysis workers manually open each bag one by one and put it into an automatic dissolution apparatus to prepare dialysate, there is a risk of quantity differences due to human error. There is a high risk that foreign matter such as dust, germs, human hair, etc. adhering to the bag will be mixed when the automatic dissolving device is introduced. There is also a problem that the automatic melting device malfunctions.

Further, when the bag body is cut and opened with a blade, chips of the bag body are generated at the time of cutting, and if the chips fall into the automatic melting apparatus, there is a risk of causing a malfunction of the automatic melting apparatus. Further, when the dialysis agent adheres to the blade, the blade is easily corroded by the components of the dialysis agent, which hinders the opening operation. And the dialysis agent adhering to the blade tends to absorb moisture and deteriorate. If the deteriorated dialysis agent is mixed in the dialysis agent in the automatic dissolution apparatus in the subsequent dissolution operation, the prepared dialysis solution may be contaminated. "
Patent Document 1 relates to this problem: “A bag body made of a flexible sheet material, in which a dialysis agent can be stored, and a dialysis agent discharge passage formed at the lower end of the bag body and communicating with the bag body. A dialysis agent storage container having a cylindrical outlet member to form a compartment, and a bag expanded by enclosing gas is inserted into the outlet member to close the dialysis agent discharge path, A part of the bag is fixed to the inside of the outlet member, the outlet member below the bag is sealed, the gap between the sealing portion and the bag is cut, and the outlet side of the dialysis agent discharge path is opened. The bag is contracted by discharging gas, and the dialysis agent in the bag body is discharged to the outside through the dialysis agent discharge path. With this configuration, in Patent Document 1, the automatic dissolution apparatus is set. In this case, the dialysis agent discharge path, which is the dialysis agent supply port, is sealed until use. Therefore, when the dialysis agent is put into the automatic dissolution apparatus, dust and bacteria adhering to the dialysis agent storage container are mixed into the automatic dissolution apparatus. In addition, the bag can be contracted in a state where it is set in the automatic dissolution apparatus, and the dialysis agent can be gradually dropped, and dust generation due to discharge of the dialysis agent can be suppressed. In addition, the empty used dialysis agent storage container can be easily reduced in volume, facilitating disposal, and the dialysis agent discharge passage is opened to discharge the dialysis agent. In addition, there is no need to open it with a blade, etc. Therefore, chips of the bag body are not generated, and malfunction of the automatic melting apparatus due to mixing of chips does not occur. The blade is corroded and the efficiency of the opening operation In addition, the dialysis agent that has deteriorated due to adhesion to the blade is not mixed into the dialysis agent in the automatic dissolution apparatus, and the risk of contaminating the prepared dialysate can be eliminated. " Have been described.

  However, in the dialysis agent storage container 1 of Patent Document 1, the bag 7 expanded by enclosing gas is inserted into the outlet member 4 to close the dialysis agent discharge passage 3, and Since the outlet part 4 is fixed to the inside of the outlet member 4 and the outlet member 4 below the bag 7 is sealed, the structure of the container for inserting the bag 7 is complicated, and the manufacturing cost of the container is high. There is.

Furthermore, the container of Patent Document 1 needs to have a conical structure for the discharge part in order to improve the powder discharge. However, if the discharge part has a conical structure, the powder storage space in the container is reduced. In addition, a large container is required to fill a predetermined amount of medicine. In addition, when a plurality of containers having such a large shape are put in a case, the space ratio in the transport case increases and the transport cost also increases.
JP2006-158824, claims, drawings

  The present invention has been made in view of the above circumstances, and has a simple structure composed of an outer cylinder member and an inner cylinder member, the contents do not leak to the outside, and there is no problem of deterioration of the environment at the time of transfer. Moreover, the container which can exhibit the effect that a foreign material may not mix carelessly from the outside is provided. Moreover, since the shape of the container is arbitrary and the discharge part does not need to have a conical structure, it is designed in a rectangular shape so that the storage capacity is high and the space ratio in the transport case can be kept low. be able to.

  In order to solve the above problems, the present invention has the following configuration. Here, for easy understanding, reference numerals corresponding to the drawings are attached, but the present invention is not meant to be specified by the configuration of the drawings.

(1) A closed outer cylinder member 10 that seals the peripheral side portions 11 and 11 and the first and second end portions 12 and 13 and an inner cylinder member 20 that is built in the outer cylinder member. In the space formed between the peripheral side portions 11, 11 of the outer cylinder member, the second end portion 13, and the first end portion 21 of the inner cylinder member, the liquid or powder content C is present. A storage container to be stored,
The outer cylinder member 10 is formed with a scheduled opening portion 16 for opening the outer cylinder member on the first end side 12 of the outer cylinder member circumferential side portion,
The inner cylindrical member 20 includes sealed peripheral side portions 23, 23, a first end portion 21 that is opened or scheduled to be opened, and a second end portion 22 that has an opening portion or a planned opening portion. Forming,
The first end portion 21 of the inner cylinder member 20 is positioned on the second end side from the scheduled opening portion 16 of the outer cylinder member 10, and seals between the outer peripheral surface of the inner cylinder member and the inner peripheral surface of the outer cylinder member. The storage container, wherein the inner cylinder member 20 is attached to the outer cylinder member 10.

(2) The storage container according to (1), wherein the outer cylinder member 10 is provided with a gas or liquid introduction hole forming portion 17 on a peripheral side portion.

(3) A means for linearly opening the planned opening portion 16 of the first end portion 12 of the outer cylinder member and that it is formed by one or two means selected from the group consisting of chuck seals. The storage container according to (1) or (2), which is characterized.

(4) The inner cylinder member 20 has a trapezoidal shape in which the bottom on the first end 21 side is long and the upper side on the second end 22 side is short (1) to (3) A storage container according to any one of the above.

(5) The storage according to (4), wherein the contents are liquid and the inclination angle of the peripheral side portions 23 and 23 with respect to the bottom of the trapezoidal inner cylinder member 20 is 10 to 90 degrees. container.

(6) The content is powdery, and the inclination angle of the peripheral side portions 23 and 23 with respect to the bottom of the trapezoidal inner cylinder member 20 is 25 to 90 degrees. Storage container.

(7) The storage container according to any one of (1) to (6), wherein the inner cylinder member 20 is formed of a plastic material or a laminate made of a plastic material.

(8) The inner cylinder member 20 is composed of a laminate of an engineering plastic material and / or a polyolefin material and a polyolefin-based elastomer material, and the polyolefin-based elastomer material is arranged on the inner side and is weakly bonded. The storage container according to any one of (1) to (7).

(9) The inner cylinder member has a content contact surface and a content non-contact surface, and part or all of the content non-contact surface (excluding the sealing portion) is a low melting point polyolefin material or an easily peelable material. The storage container according to any one of (1) to (8), wherein the storage container is formed by one or more means selected from the group consisting of resealable materials.

(10) A part or all of the content non-contact surface is a planned opening portion of the first end portion and / or a planned opening portion of the second end portion of the inner cylinder member (9). ) Storage container.

(11) A storage container for transferring the contents C to the second container 30, which is a place where the opening scheduled portion 16 of the outer cylinder member 10 and the first end 21 of the inner cylinder member 20 are attached. The length between them forms a skirt 18 that is long enough to cover the contents filling inlet 31 of the second container 30 to which the contents are transferred (1) to ( The storage container according to any one of 10).

(12) A method of transferring the contents in the storage container to the second container using the storage container according to any one of (1) to (11),
Opening the planned opening portion 16 of the storage container containing the liquid or powdered contents and opening the first end portion 11 of the closed outer cylinder member 10; and
A step of disposing the first end portion 11 side of the opened outer cylinder member on the content filling inlet portion 31 provided in the second container 30;
Applying physical and / or mechanical pressure to the contents in the outer cylinder member to move the contents downward by gravity; and
As the contents move, the second end 22 of the inner cylinder member 20 is reversed and moved to the lower side of the first end 21 through the opened first end 21 of the inner cylinder member. Or with the movement of the contents, the planned opening portion of the first end portion of the inner cylinder member is opened, and the second end portion of the inner cylinder member passes through the opened first end portion 21 of the inner cylinder member. Reversely moving the end portion 22 of the first end portion 21 to the lower side of the first end portion 21;
The contents are transferred into the second container through the opening 25 of the inverted second end 22 of the inner cylinder member 20, or the second of the inner cylinder member 20 is moved with the movement of the contents. The contents in the storage container are transferred to the second container, wherein the opening is planned to be opened at the end 22 and the contents are transferred into the second container through the opened opening. Method.

(13) The means for applying physical and / or mechanical pressure to the contents in the outer cylinder member blows air into the outer cylinder member and presses the contents through the outer cylinder member. (12) The method according to (12), which is one or more means for blowing liquid.

(14) The outer cylinder member is provided with a gas or liquid introduction hole forming portion 17 on the peripheral side portion, and a hole is formed in the formation portion, and the gas or liquid is blown from the introduction tube through the introduction tube. The method according to (12) or (13), wherein physical and / or mechanical pressure is applied to the contents in the outer cylindrical member.

(15) The contents in the outer cylinder member are mixed with gas, and physical and / or mechanical pressure is applied to the contents in the outer cylinder member by pushing the outer cylinder member from the outside. The method according to (12) or (13).

(16) In the outer cylinder member, only the contents are accommodated without mixing gas, and the pressure applied to the contents causes the outer cylinder member to communicate with the outside air and sends the outside air into the outer cylinder member. The method according to (12) or (13), wherein physical and / or mechanical pressure is applied to the contents in the outer cylinder member.

(17) Inserted through the first end of the opened outer cylinder member, the open or planned opening of the first end of the inner cylinder, the opening or planned opening of the second end. (12) or applying a physical and / or mechanical pressure to the contents in the outer cylinder member by ejecting the liquid in the second container or the separately supplied liquid from the nozzle 33. The method according to (13).

(18) The method according to any one of (12) to (17), wherein the storage container for the contents is a dialysis agent storage container, and the second container is an automatic dissolution apparatus.

(Definition)
In the claims and description,
“The closed outer cylinder member sealing the peripheral side portion and the first and second end portions” means the manufacturing process of the outer cylinder member, the number of materials for creating the outer cylinder member, It does not specify the shape. It means a state in which the outer cylinder member is isolated from the outside and the content does not leak to the outside, whether it is liquid or powder.

“Pharmaceuticals” has a broad meaning and includes not only narrowly-defined pharmaceuticals but also health foods.

The “storage container” is a flexible bag-like container for replacing contents with another container. For example, a container having a fixed shape such as glass or metal is included in the “storage container” of the present invention. Not included.

The “unscheduled opening portion” means a portion that is first opened when the contents replacement operation is started using the storage container. The “scheduled opening portion” of the present invention includes a structure in which a notch, a cut line, and a cut tape are formed on the scheduled opening portion for easy opening. In addition, the “scheduled opening portion” of the present invention includes not only a structure intended to be opened manually but also a structure intended to be mechanically opened.

“Plastic material” refers to engineering plastic material, polyolefin material, polyolefin elastomer material, and the like.

“Engineering plastic material” refers to a material having relatively high strength, such as polyamide, polyester such as polyethylene terephthalate, and polycarbonate.

The “polyolefin material” refers to a material such as PE (polyethylene), PP (polypropylene), ethylene-α-olefin copolymer, propylene-α-olefin copolymer.

“Polyolefin elastomer material” means EVA (ethylene vinyl acetate copolymer), SEBS (styrene-ethylene-butadiene-styrene), EPR (ethylene-propylene rubber), EBR (ethylene-butadiene rubber), HEBS (hydrogenated) (Ethylene-butadiene-styrene) or a mixture of these materials and polyolefin materials.

The “expected opening portion” refers to a portion that is closed before the discharge of the contents using the storage container is started, but is naturally opened when the discharge is started. In other words, the “scheduled opening portion” is joined with a weak force, but the joining force means a portion that can be automatically opened by a pressing force when the contents drop by gravity. In addition, the “expected opening portion” of the present invention includes a configuration in which only overlapping films are formed even if they are not joined.

The “expected opening portion” refers to a portion that is closed before the content replacement operation is started using the storage container, but is naturally opened when the replacement operation is started. In other words, although it is joined with a weak force, the joining force means a portion in a state where it can be automatically opened by a pressing force when the contents fall.

“Low-melting polyolefin material” refers to an ethylene-α-olefin copolymer or a mixture of polyethylene and ethylene vinyl acetate copolymer. Say the material.

“Easily peelable material” means a material made of polypropylene, polyethylene, polystyrene, ethylene vinyl acetate, etc. that can be easily peeled off. The easily peelable material is applied to the film. Also included. Examples of the peeling mode include cohesive peeling, delamination, and interfacial peeling.

The “resealable material” refers to a structure in which convex protrusions and concave grooves are joined and joined, represented by a chuck seal, and can be easily detached.

“Physical and / or mechanical pressure” means by injecting liquid or gas into the outer cylinder member filled with the contents, or by applying an external force to the outer cylinder member, or by combining these. Includes pressure on the contents.

  According to the present invention, since the planned opening portion of the outer cylinder member is not in contact with the contents, there is no fear that the opening cutter or the like may inadvertently touch the contents at the time of opening, so that sanitary discharge is possible. Moreover, simply opening the planned opening portion of the outer cylinder member does not cause the contents in the container to go outside or come into contact with the outside air, and applies physical and mechanical pressure to the outer cylinder member and contents. As a result, the contents fall for the first time. For this reason, the timing of discharge of the contents can be appropriately performed, and the contents can be discharged after the container is moved to a predetermined discharge position. As a result, the contents do not leak to the outside, the generation of dust can be reduced, and there is no problem of environmental degradation during discharge. Moreover, there is no possibility that foreign matter is inadvertently mixed from the outside. In particular, the entire content non-contact surface of the inner cylinder member is made of a low-melting-point polyolefin material, and the inner surfaces are bonded to each other in a peelable manner, or the ends (openings) of the content non-contact surface of the inner cylinder member are low. If formed with a melting point polyolefin material, easily peelable material, resealable material, etc., the contents will not enter the inner cylinder member when the container is stored, and the inner cylinder member is sealed when opened. Therefore, it is possible to prevent the contents from going out more reliably.

  Furthermore, if it is a trapezoidal inner cylindrical member, especially when the contents are liquid, the tilt angle is 10 to 90 degrees, and when the contents are powdery, if it is about 25 to 90 degrees, the funnel is reversed. The contents are smoothly dropped and do not remain in the outer cylinder member.

  Furthermore, by forming a sufficiently long skirt portion, it is possible to more reliably prevent foreign matters from being mixed from the outside during transfer, and to reduce dust generation.

  And, the present invention has a very simple configuration of only the bag material in which the inner cylinder member is arranged in the outer cylinder member, and it is not necessary to attach an opening of another material to the opening of the inner cylinder member. A bag-like container can be manufactured at low cost.

  Moreover, since the shape of the container is not limited, by designing it into a rectangular shape, the storage volume is high and the space ratio in the transport case can be kept low.

  Furthermore, the present invention can be allowed to fall naturally by its own weight, but by applying physical and mechanical external pressure, the liquid or powdered contents can be expelled to a specific position in a short time. , Can increase the discharge efficiency.

  Hereinafter, the present invention will be described with reference to the illustrated embodiments. FIG. 1 is a front view of a storage container in which a liquid or powder content of a medicine or the like (for example, a dialysis agent) is stored. FIG. 4 is a side view showing a state in which the contents are accommodated. The storage container includes an outer cylinder member 10 and an inner cylinder member 20.

  The outer cylinder member 10 has a rectangular shape and seals the inside by sealing both sides 11 and 11, the lower end portion 12 (first end portion) and the upper end portion 13 (second end portion) constituting the peripheral side portion. Blocked. One or two or more holes 14 for container transportation or container suspension are provided at the upper end sealing portion of the outer cylinder member 10. Notches 15 and 15 for creating a trigger for opening are formed in the sealing portions on both sides at positions slightly above the sealing portion on the lower end portion of the outer cylinder member 10, and the notches 15 and 15 on both sides are formed. A line (indicated by a broken line) connecting the two becomes the scheduled opening portion 16 of the outer cylinder member 10. The planned opening portion 16 can be easily opened in a straight line by giving the film a straight cut or attaching a cut line or a cut tape. Further, the opening-scheduled portion 16 may be formed by a chuck seal. The chuck seal is formed between the opening-scheduled portion 16 formed by a cut line or a cut tape and the first end portion 21 of the inner cylinder member. You may arrange in. In this case, even if the scheduled opening portion 16 is opened, the container is kept airtight by the chuck seal.

  Further, the chuck seal is directional, and has a characteristic that it is easy to open from one side (for example, the outside) and is difficult to open from the opposite side (for example, the inside). Therefore, when the chuck seal is used in a mechanism for opening from the first end 12 side of the outer cylinder member using an artificial or mechanical opening means, it is easy to open from the outside (first end 12 side), and the bag It is preferable to install in a direction that is difficult to open from the inside. On the contrary, when the chuck seal is not opened from the first end 12 side of the outer cylinder member, that is, when a mechanism for introducing gas or liquid into the bag and opening them with the pressure of the contents is used, It is preferable to install in a direction that is easy to open from the outside and difficult to open from the outside.

  The outer cylinder member 10 is formed of polyester, polyethylene material, or the like, and a gas or liquid introduction hole forming portion 17 in which a piece of rubber material, plastic material, or the like is pasted is formed on a peripheral side surface of the outer cylinder member. Even if a hole is drilled, the material is not torn to other places. The gas or liquid introduction hole forming portion 17 is not limited to the rubber material, and may be formed so that the container material is not torn and leaked when the gas or liquid is introduced.

  The inner cylinder member 20 is in the outer cylinder member, has a trapezoidal shape, and has a lower end 21 (first end), an upper end 22 (second end) shorter than the lower end surface, and these lower ends. Part 21 and inclined sides 23, 23 (constituting a peripheral side part) connecting upper end part 22. The outer peripheral surface of the inner cylinder member lower end portion 21 and the inner peripheral surface of the outer cylinder member have the same length, and the outer peripheral surface of the inner cylinder member lower end portion 21 is sealed with the inner peripheral surface of the outer cylinder member 10. The sealed lower end 21 of the inner cylinder member is positioned above the planned opening portion 16 of the outer cylinder member. The length between the lower end portion 21 of the inner cylinder member and the planned opening portion 16 of the outer cylinder member (hereinafter, this portion is referred to as the skirt portion 18) is the second container 30 for transfer (for example, automatic melting) It has a length sufficient to cover the content filling port (opening) of the apparatus. In other words, when the inner cylinder member upper end portion 22 is inverted and positioned below the inner cylinder member lower end portion 21, the inverted inner cylinder member upper end portion 22 is in the skirt portion 18 or the second container 30. It is in the contents filling port. Both sides of the inner cylinder member 20 are sealed. Also, the lower end is opened (forms an open portion 24), and the upper end forms an opening 25. The inclination angle on both sides of the inner cylinder member is 10 to 90 degrees when the contents are liquid, and 25 to 90 degrees when the contents are powder, and the contents are easily slipped down when reversed.

  In addition, although the trapezoid shape was mentioned as a preferable form of an inner cylinder member, if it is the form discharged | emitted smoothly without the content remaining in the content filling inlet part 31 of the 2nd container 30, it will not be limited to a trapezoid shape.

  The inner cylinder member 20 is formed of a polyolefin material such as polyethylene or polypropylene, an engineering plastic material such as polyamide or polyester, or a laminate made of polyethylene / polyester. In addition, the inner cylinder member 20 is particularly composed of a mixture of polyethylene and ethylene vinyl acetate copolymer and a laminate of polyethylene, and by arranging the mixture of polyethylene and ethylene vinyl acetate copolymer inside, Since the non-contact surface of the contents of the inner cylinder member is weakly bonded so that it can be reattached, it is preferable. The material is not limited to the above, and other materials may be used as long as the object that the non-contact surface of the contents can be weakly joined can be achieved.

  In addition, the thickness of the inner cylinder member 20 is preferably 100 μm or less, and more preferably 80 μm or less in order to facilitate reversal at the time of discharging the contents. However, if it is too thin, there is a problem in strength, so 20 μm or more is preferable.

  In the above example, the lower end 21 of the inner cylinder member 20 is open and the upper end 22 is opened. However, a part or all of the contents non-contact surface (excluding the sealing part) of these inner cylinder members (ex. , An opening planned portion of the first end portion and / or a second opening scheduled portion of the second end portion) of a low melting point polyolefin material, an easily peelable material, or a resealing material represented by the above example. It is also possible to use or to join them by a combination thereof so as to form an open or planned opening portion. That is, it is not opened or opened when the contents are accommodated, but is opened or opened when the contents fall.

  Moreover, in said example, although the outer peripheral surface of the inner cylinder member lower end part 21 and the outer peripheral member inner peripheral surface were made into the same length, this invention is not limited to this. When the outer peripheral surface of the inner cylindrical member lower end portion 21 is shorter than the inner peripheral surface of the outer cylindrical member, the outer peripheral surface of the inner cylindrical member lower end portion 21 is sealed at a predetermined location on the inner peripheral surface of the outer cylindrical member, and the remaining portion is sealed to the outer cylinder. The inner peripheral surfaces of the members can be sealed with each other. In short, it is sufficient that the contents can be stored.

  Next, with reference to FIG. 2 and FIG. 5, the usage method of the container comprised in this way is demonstrated.

  The planned opening portion 16 of the storage container containing the liquid or powder content is opened by mechanical and / or artificial means, and the lower end portion 12 of the closed outer cylinder member 10 is opened. In this state, the contents do not fall from the lower end portion 12 due to an antagonistic action between the gravity that acts to drop the contents and the atmospheric pressure that pushes up the contents, and the structural characteristics of the storage container.

  In this state, the lower end side of the outer cylinder member is disposed on the opening (content filling inlet 31) formed in the second container 30, and the second skirt portion 18 of the outer cylinder member The content filling inlet 31 of the container 30 is covered. Thus, the contents do not scatter to the outside at the time of transfer, and foreign matters are not mixed from the outside. At this time, the effect can be increased by using another mechanism (for example, a melting device) that closely contacts the inner surface of the skirt 18 and the outer surface of the content filling inlet 31.

  Next, physical and / or mechanical pressure is applied to the contents in the outer cylinder member, and the contents are moved downward by the pressure and gravity. Along with the movement of the contents, the upper end portion 22 of the inner cylinder member 20 is reversed and moves to the lower side of the lower end portion 21 of the inner cylinder member 20.

  The opening 25 of the upper end 22 of the inner cylinder member 20 communicates with the content filling inlet 31 of the second container 30 through the inside of the skirt 18 of the outer cylinder member 10. As a result, the contents of the container are discharged into the second container through the opening 25 of the inverted upper end 22 of the inner cylinder member 20 and the contents filling inlet 31 of the second container 30. Here, the opening portion 25 should be communicated with the content filling inlet portion 31, but may not be communicated depending on how the inner cylinder member is reversed, and the content may leak out from the filling inlet portion 31. . In order to avoid this risk, it is desirable to install another mechanism (for example, a melting device) that closely contacts the inner surface of the skirt 18 and the outer surface of the content filling inlet 31 described above.

  As a means for applying pressure to the contents in the outer cylinder member, any means such as blowing air into the outer cylinder member, blowing liquid into the outer cylinder member, or pressing the contents via the outer cylinder member is taken. be able to.

  For example, a hole is formed in the gas or liquid introduction hole forming portion 17 in the peripheral side portion of the outer cylinder member, air is blown into the hole through the nozzle 40, and air pressure is applied to the outer cylinder member to lower the contents. Can be moved in the direction. Further, if a large amount of gas is mixed at the time of filling the contents, the contents can be dropped into the second container by simply pressing the outer cylinder member 20 from the outside.

  In addition, when only the contents are stored in the outer cylinder member without mixing air (so-called vacuum packing), the contents can be obtained by putting the outer air in the outer cylinder member by communicating the outer cylinder member with the outside air. Objects can be dropped into the second container.

  When the lower end portion 21 of the inner cylinder member 20 is a planned opening portion or the upper end portion 22 is a planned opening portion, these planned portions are automatically released or opened by the pressing force when the contents move. The

  In addition, when the second container 30 for transfer is an automatic dissolution apparatus, as shown in FIG. 3, the nozzle 32 is inserted into the container from the automatic dissolution apparatus, and the liquid is blown from the nozzle, whereby the contents It can also be transferred to an automatic dissolution apparatus while dissolving the product.

  When air or liquid is blown in, it is easier to discharge with a certain level of pressure (speed), specifically 0.1 to 25 kPa. If the pressure is too strong, the container may rupture, and if it is too weak, it takes time to open and discharge, and further causes a problem of defective discharge.

  As mentioned above, although the storage container of this invention and its usage method were demonstrated based on drawing, this invention is not limited to what was described in drawing. For example, the outer cylinder member is not limited to a rectangle, and is not particularly limited as long as it can accommodate contents. Further, the inner cylinder member is not limited to a trapezoidal shape, and any member can be used as long as the contents can be dropped at the time of transfer. The material of the inner cylinder member and the outer cylinder member is not particularly limited as long as the contents can be accommodated flexibly and the contents do not leak to the outside. The contents are also liquid and powder, but are not limited to the above as long as they have fluidity that can be discharged from the discharge portion, such as slurry, granules, and blocks.

Example 1
In the storage container shown in FIG. 1, a polyester / silica-deposited polyester / polyethylene laminate bag was used as the outer cylinder member, and polyethylene / vinyl acetate copolymer-containing polyethylene (adhesive surface) was prepared as the inner cylinder member. The size of the container is as follows.

L (length): 400mm
W (width): 240mm
α (angle): 60 °
Inner cylinder thickness: 50 μm
l (skirt length): 40mm
The outer cylinder member lower end portion 12 of the container is sealed by heat sealing, and powder is formed in a space formed by the inner cylinder member lower end portion 21, the peripheral side portion 11, and the outer cylinder member upper end portion 13 (hereinafter referred to as a drug filling portion). 2856 g of dialysate was filled, and the upper end portion 13 of the outer cylinder member was heat sealed.

  The hole 14 of the drug container was hooked and the drug container was suspended, and was placed on the content filling inlet 31. The planned opening portion 16 was cut and opened, and the skirt portion 18 from which the medicine was discharged was positioned outside 31. Moreover, in order to measure the internal pressure of the medicine filling portion, a tube connected to a pressure gauge was inserted into the medicine filling portion.

  An air nozzle was inserted into the gas introduction hole forming portion 17 and air adjusted to a source pressure of 50 kPa was introduced at a flow rate of about 15 L / min for about 5 to 10 seconds. After the drug filling portion swelled, the trapezoid of the inner cylinder was inverted to form an inverted trapezoid funnel, and the powder was discharged, and the entire amount moved to the container 30 in about 10 seconds. At this time, the maximum pressure in the drug filling portion was 2 kPa.

  According to the container of Example 1, it was confirmed that the contents can be smoothly discharged in a short time without applying a large pressure by a simple method of air introduction.

(Example 2)
At the same time as filling the powder dialysis agent into a container having the same shape and size as in Example 1, the drug filling portion was filled with as much air as possible, and the upper end portion 13 of the outer cylinder member was heat sealed.

  The hole 14 of the drug container was hooked and the drug container was suspended, and was placed on the content filling inlet 31. The planned opening portion 16 was cut and opened, and the skirt portion 18 from which the medicine was discharged was positioned outside 31.

  Next, an external pressure plate (about 50 mm × about 250 mm) was pressed on both sides of the medicine filling part from both sides. The drug filling part that has been heat-sealed with a lot of air is pushed by the external pressure plate and the internal pressure increases, so that the trapezoid of the inner cylinder is reversed and the powder is discharged like a reverse trapezoid funnel, The whole amount moved to the container 30 in about 10 seconds. At this time, the maximum pressure in the drug filling portion was 2.5 kPa.

  According to the container of Example 2, by introducing air into the storage container in advance, the bag is compressed from the outside by a pressure plate or the like, and can be smoothly performed in a short time without applying a large pressure. It was confirmed that the contents could be discharged.

(Example 3)
A powder dialysis agent was filled in a container having the same shape and size as in Example 1, and the upper end 13 of the outer cylinder member was heat sealed. The hole 14 of the drug container was hooked and the drug container was suspended, and was placed on the content filling inlet 31. The planned opening portion 16 was cut and opened, and the skirt portion 18 from which the medicine was discharged was positioned outside the content filling inlet portion 31.

  Next, a nozzle for injecting dissolved water (pure water) was inserted into the liquid introduction hole forming portion 17, and the dissolved water was introduced at a flow rate of about 1 L / min. After the drug filling part swelled, the trapezoidal shape of the inner cylinder was reversed to form an inverted trapezoid funnel, and the powder and dissolved water were discharged in a suspended state. The slight amount of the remaining powder also moved to the container 30 due to the showering effect of pure water from the injection nozzle.

  It was confirmed that the contents can be discharged smoothly in a short time without scattering of dust by a simple method of introducing water for dissolving the contents.

Example 4
In the container of FIG. 1, a container was prepared in which the materials of the outer cylinder member and the inner cylinder member were the same as those in Example 1, and the dimensions were changed as follows. Further, a chuck seal was provided immediately below the lower end portion 21 of the inner cylinder member of the container.

L (length): 400mm
W (width): 240mm
α (angle): 25 °
Inner cylinder thickness: 50 μm
l (skirt length): 50mm
Chuck seal: Immediately below the inner cylinder member lower end portion 21 The outer cylinder member lower end portion 12 is sealed by heat sealing, and the inside of the space formed by the inner cylinder member lower end portion 21, the peripheral side portion 11, and the outer cylinder member upper end portion 13 (hereinafter, 2856 g of powder dialysis agent was filled in the medicine filling part), and 13 was heat-sealed. The hole 14 of the drug container was hooked and the drug container was suspended, and was placed on the content filling inlet 31. The planned opening portion 16 was cut and opened, and the skirt portion 18 from which the medicine was discharged was positioned outside 31. Moreover, in order to measure the internal pressure of the medicine filling portion, a tube connected to a pressure gauge was inserted into the medicine filling portion.

  An air nozzle was inserted into the gas introduction hole forming portion 17 and air adjusted to an original pressure of 50 kPa was introduced at a flow rate of about 15 L / min for about 5 to 10 seconds. After the drug filling portion swelled, the chuck seal was opened, the trapezoid of the inner cylinder was inverted, and the powder was discharged in the shape of an inverted trapezoid funnel, and the entire amount moved to the container 30 in about 10 seconds. At this time, the maximum pressure in the drug filling portion was about 18 kPa.

  In Example 4, by further adding a strong seal layer such as a chuck seal, the trapezoid of the drug storage portion is not partially inverted by an external pressure such as drug transportation, and the drug in the packaging container is stabilized. It was confirmed that the contents can be discharged smoothly in a short time by applying a pressure that can be held and has no problem in use.

The figure which shows an example of the storage container of this invention. Explanatory drawing which shows the usage method of the storage container. Explanatory drawing which shows the other usage method. It is the figure which looked at the storage container of FIG. 1 from the side surface, and shows the state before discharge | filling with the content. It is the figure which looked at the storage container of FIG. 1 from the side, and shows the state which discharges the contents.

Explanation of symbols

DESCRIPTION OF SYMBOLS 10 ... Outer cylinder member 11 ... Both sides of outer cylinder member 12 ... Outer cylinder member lower end part 13 ... Outer cylinder member upper end part 14 ... Hole for container conveyance or container suspension 15 ... Notch 16 ... Opening scheduled part 17 ... Gas or Liquid introduction hole forming part 18 ... Skirt part 20 ... Inner cylinder member 21 ... Inner cylinder member lower end part 22 ... Inner cylinder member upper end part 23 ... Inner cylinder member peripheral side part 24 ... Opening part 25 ... Opening part 30 ... For transfer Second container 31 ... Contents filling inlet 32 ... Nozzle 40 ... Nozzle C ... Contents L ... Vertical length of container W ... Horizontal width of container α ... Angle of trapezoid l ... Length of drug discharge part

Claims (18)

The closed outer cylinder member which sealed the circumference side part and the 1st and 2nd edge part, and the inner cylinder member built in this outer cylinder member were comprised, the circumference side part of the outer cylinder member, 2nd A storage container in which a liquid or powdered content is accommodated in a space formed between the end of the inner tube and the first end of the inner cylinder member,
The outer cylinder member forms an opening scheduled portion for opening the outer cylinder member on the first end side of the outer cylinder member circumferential side part,
The inner cylinder member
(1) a sealed peripheral side part;
(2) a first end portion of the inner cylinder member opened or scheduled to be opened;
(3) The first of the end portion and a said outer cylinder second second ends on the end side Ru is disposed as an opening or opening scheduled portion of the member, the outer tubular member first It is formed so as to be movable by inverting to the end side,
The first end portion of the inner cylinder member is located between the scheduled opening portion of the outer cylinder member and the second end portion side of the outer cylinder member, and is formed between the outer peripheral surface of the inner cylinder member and the inner peripheral surface of the outer cylinder member. By sealing the gap, the inner cylinder member is attached to the outer cylinder member ,
The storage container , wherein the inner cylinder member is formed of a plastic material or a laminate made of a plastic material, and is weakly bonded so as to be peelable at the contact surfaces of the inner cylinder member inner surfaces . The storage container according to claim 1, wherein the outer cylinder member is provided with a gas or liquid introduction hole forming portion on a peripheral side portion. 2. The opening scheduled portion at the first end of the outer cylinder member is formed by one or two means selected from the group consisting of a means for linearly opening and a chuck seal. Or the storage container of 2. The storage container according to any one of claims 1 to 3, wherein the inner cylindrical member has a trapezoidal shape with a long bottom on the first end side and a short upper side on the second end side. . The storage container according to claim 4, wherein the contents are liquid, and the inclination angle of the peripheral side portion with respect to the bottom side of the trapezoidal inner cylinder member is 10 to 90 degrees. The storage container according to claim 4, wherein the contents are powdery, and the inclination angle of the peripheral side portion with respect to the bottom side of the trapezoidal inner cylinder member is 25 to 90 degrees. The inner cylinder member is composed of a laminate of engineering plastic material and / or polyolefin material and polyolefin elastomer material. The polyolefin elastomer material is placed inside and the polyolefin elastomer material placed inside contacts with each other. container according to any one of claims 1 to 6, characterized in that it is weakly bonded in the plane. The inner cylinder member has a content contact surface that comes into contact with the content when the content is contained , and a content non-contact surface that does not come into contact with the content when the content is contained. Part or all of the content non-contact surface (excluding the sealing portion) is formed by one or more means selected from the group consisting of low melting point polyolefin materials, easily peelable materials, and resealable materials. container according to any one of claims 1 to 7, characterized in that is. Portion or all portions of the contents of the non-contact surfaces, according to claim 8, characterized in that a first release scheduled portion of the end and / or the opening scheduled portion of the second end of the inner cylindrical member Storage container. A storage container for transferring the contents to the second container, the length between the opening scheduled portion of the outer cylinder member and the location where the first end of the inner cylinder member is attached is The storage container according to any one of claims 1 to 9 , wherein a skirt portion having a length sufficient to cover the content filling inlet portion of the second container to be transferred is formed. A storage container in which the liquid or powder content according to any one of claims 1 to 10 is stored, and means for applying physical and / or mechanical pressure to the content in the outer cylindrical member of the storage container And a second container provided with a content filling inlet for transferring the contents in the storage container. The apparatus transfers the contents in the storage container to the second container. 12. The apparatus according to claim 11, wherein the contents storage container is a dialysis agent storage container, and the second container is an automatic dissolution apparatus. The means for applying physical and / or mechanical pressure to the contents in the outer cylinder member blows air into the outer cylinder member, presses the contents through the outer cylinder member, and blows liquid into the outer cylinder member Device according to claim 11 or 12, characterized in that it is one or more means. A method of operating a device according to any of claims 11 to 13,
Opening the opening scheduled portion of the storage container containing the liquid or powdered contents and opening the first end of the closed outer cylinder member; and
A step of disposing the first end portion side of the opened outer cylinder member on the content filling inlet portion provided in the second container;
Applying physical and / or mechanical pressure to the contents in the outer cylinder member to move the contents downward by pressure and gravity;
Step with the movement of the contents, the second end of the inner cylindrical member, through a first end which is open in the inner cylindrical member, to anti-metastatic moving below the first end When,
The contents are transferred into the second container through the opening of the inverted second end of the inner cylinder member, or the opening of the second end of the inner cylinder member as the contents move. An operation method for an apparatus for transferring contents in a storage container to a second container, wherein the planned part is opened, and the contents are transferred into the second container through the opened opening planned part. The outer cylinder member is provided with a gas or liquid introduction hole forming portion on the peripheral side portion, and a hole is formed in the formation portion, and the gas or liquid is blown from the introduction tube through the introduction tube. 15. The method of operating a device according to claim 14, wherein physical and / or mechanical pressure is applied to the contents of the device . A gas is mixed in the contents in the outer cylinder member, and physical and / or mechanical pressure is applied to the contents in the outer cylinder member by pushing the outer cylinder member from the outside. A method of operating the device according to claim 14 or 15. In the outer cylinder member, only the contents are stored without mixing gas, and the pressure applied to the contents causes the outer cylinder member to communicate with the outside air and sends the outside air into the outer cylinder member. The method for operating an apparatus according to any one of claims 14 to 16, wherein physical and / or mechanical pressure is applied to the contents in the outer cylindrical member by artificially pressing. From the first end of the opened outer cylinder member, the open or planned opening of the first end of the inner cylinder, the nozzle inserted through the opening or planned opening of the second end The physical and / or mechanical pressure is applied to the contents in the outer cylinder member by ejecting the liquid in the second container or the separately supplied liquid. A method for operating the device according to claim 1 .

Images