JP5140425B2 - 特定の核酸を同時に増幅する方法 - Google Patents

特定の核酸を同時に増幅する方法 Download PDF

Info

Publication number
JP5140425B2
JP5140425B2 JP2007527104A JP2007527104A JP5140425B2 JP 5140425 B2 JP5140425 B2 JP 5140425B2 JP 2007527104 A JP2007527104 A JP 2007527104A JP 2007527104 A JP2007527104 A JP 2007527104A JP 5140425 B2 JP5140425 B2 JP 5140425B2
Authority
JP
Japan
Prior art keywords
target
selector
sequence
nucleic acid
fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2007527104A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007537751A5 (OSRAM
JP2007537751A (ja
Inventor
ダール、フレドリック
Original Assignee
オリンク・アーベー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by オリンク・アーベー filed Critical オリンク・アーベー
Publication of JP2007537751A publication Critical patent/JP2007537751A/ja
Publication of JP2007537751A5 publication Critical patent/JP2007537751A5/ja
Application granted granted Critical
Publication of JP5140425B2 publication Critical patent/JP5140425B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C12Q1/6855—Ligating adaptors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2007527104A 2004-05-18 2005-03-31 特定の核酸を同時に増幅する方法 Expired - Lifetime JP5140425B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0401270-4 2004-05-18
SE0401270A SE0401270D0 (sv) 2004-05-18 2004-05-18 Method for amplifying specific nucleic acids in parallel
PCT/SE2005/000464 WO2005111236A1 (en) 2004-05-18 2005-03-31 Method for amplifying specific nucleic acids in parallel

Publications (3)

Publication Number Publication Date
JP2007537751A JP2007537751A (ja) 2007-12-27
JP2007537751A5 JP2007537751A5 (OSRAM) 2008-05-29
JP5140425B2 true JP5140425B2 (ja) 2013-02-06

Family

ID=32501910

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007527104A Expired - Lifetime JP5140425B2 (ja) 2004-05-18 2005-03-31 特定の核酸を同時に増幅する方法

Country Status (5)

Country Link
US (1) US7883849B1 (OSRAM)
EP (1) EP1747285B1 (OSRAM)
JP (1) JP5140425B2 (OSRAM)
SE (1) SE0401270D0 (OSRAM)
WO (1) WO2005111236A1 (OSRAM)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2378245A (en) 2001-08-03 2003-02-05 Mats Nilsson Nucleic acid amplification method
WO2008033442A2 (en) 2006-09-12 2008-03-20 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for performing low background multiplex nucleic acid amplification reactions
US20100291636A1 (en) * 2007-06-11 2010-11-18 Olink Genomics Ab Method for introducing common and/or individual sequence elements in a target nucleic acid molecule
WO2010126614A2 (en) 2009-04-30 2010-11-04 Good Start Genetics, Inc. Methods and compositions for evaluating genetic markers
US12129514B2 (en) 2009-04-30 2024-10-29 Molecular Loop Biosolutions, Llc Methods and compositions for evaluating genetic markers
GB0912909D0 (en) 2009-07-23 2009-08-26 Olink Genomics Ab Probes for specific analysis of nucleic acids
GB0921264D0 (en) 2009-12-03 2010-01-20 Olink Genomics Ab Method for amplification of target nucleic acid
EP2585593B1 (en) 2010-06-24 2017-03-01 Population Genetics Technologies Ltd. Methods for polynucleotide library production, immortalization and region of interest extraction
WO2012003374A2 (en) * 2010-07-02 2012-01-05 The Board Of Trustees Of The Leland Stanford Junior University Targeted sequencing library preparation by genomic dna circularization
US9163281B2 (en) 2010-12-23 2015-10-20 Good Start Genetics, Inc. Methods for maintaining the integrity and identification of a nucleic acid template in a multiplex sequencing reaction
GB2492042B (en) * 2011-05-11 2020-04-15 Agilent Technologies Inc Selector probes for nucleic acid analysis comprising at each end a non-adjacent target specific region
WO2013058907A1 (en) 2011-10-17 2013-04-25 Good Start Genetics, Inc. Analysis methods
WO2013074833A1 (en) * 2011-11-16 2013-05-23 The Board Of Trustees Of The Leland Stanford Junior University Capture probe and assay for analysis of fragmented nucleic acids
CN104093890B (zh) * 2012-01-26 2016-04-20 纽亘技术公司 用于靶向核酸序列富集和高效文库产生的组合物和方法
EP2820155B1 (en) 2012-02-28 2017-07-26 Population Genetics Technologies Ltd. Method for attaching a counter sequence to a nucleic acid sample
US8209130B1 (en) 2012-04-04 2012-06-26 Good Start Genetics, Inc. Sequence assembly
US8812422B2 (en) 2012-04-09 2014-08-19 Good Start Genetics, Inc. Variant database
US10227635B2 (en) 2012-04-16 2019-03-12 Molecular Loop Biosolutions, Llc Capture reactions
US9365896B2 (en) 2012-10-19 2016-06-14 Agilent Technologies, Inc. Addition of an adaptor by invasive cleavage
EP2920324B1 (en) 2012-11-14 2017-12-27 Olink Bioscience AB Localised rca-based amplification method
JP6335918B2 (ja) 2012-12-06 2018-05-30 アジレント・テクノロジーズ・インクＡｇｉｌｅｎｔ Ｔｅｃｈｎｏｌｏｇｉｅｓ， Ｉｎｃ． 制限酵素を用いない標的富化
JP6484177B2 (ja) 2012-12-07 2019-03-13 インヴァイティ コーポレイションＩｎｖｉｔａｅ Ｃｏｒｐｏｒａｔｉｏｎ 多重核酸検出方法
CN105026577B (zh) * 2013-03-05 2020-01-03 安捷伦科技有限公司 通过序列捕获检测基因组重排
US10114015B2 (en) 2013-03-13 2018-10-30 Meso Scale Technologies, Llc. Assay methods
KR102257912B1 (ko) 2013-03-13 2021-05-27 메소 스케일 테크놀러지즈, 엘엘시 개선된 분석 방법
US8778609B1 (en) 2013-03-14 2014-07-15 Good Start Genetics, Inc. Methods for analyzing nucleic acids
EP3005200A2 (en) 2013-06-03 2016-04-13 Good Start Genetics, Inc. Methods and systems for storing sequence read data
US11041203B2 (en) 2013-10-18 2021-06-22 Molecular Loop Biosolutions, Inc. Methods for assessing a genomic region of a subject
US10851414B2 (en) 2013-10-18 2020-12-01 Good Start Genetics, Inc. Methods for determining carrier status
GB201321123D0 (en) 2013-11-29 2014-01-15 Linea Ab Q Amplification of circular molecules
GB2520765A (en) 2013-12-02 2015-06-03 Vanadis Diagnostics Ab Multiplex detection of nucleic acids
GB2520763A (en) * 2013-12-02 2015-06-03 Vanadis Diagnostics Ab Nucleic acid probe and method of detecting genomic fragments
WO2015175530A1 (en) 2014-05-12 2015-11-19 Gore Athurva Methods for detecting aneuploidy
CN119709943A (zh) 2014-05-15 2025-03-28 中尺度技术有限责任公司 改进的测定方法
GB201413717D0 (en) 2014-08-01 2014-09-17 Olink Ab Method for selecting a target nucleic acid sequence
GB201413718D0 (en) 2014-08-01 2014-09-17 Olink Ab Method for selecting a target nucleic acid sequence
US20160048608A1 (en) 2014-08-15 2016-02-18 Good Start Genetics, Inc. Systems and methods for genetic analysis
US11408024B2 (en) 2014-09-10 2022-08-09 Molecular Loop Biosciences, Inc. Methods for selectively suppressing non-target sequences
EP3224595A4 (en) 2014-09-24 2018-06-13 Good Start Genetics, Inc. Process control for increased robustness of genetic assays
US10066259B2 (en) 2015-01-06 2018-09-04 Good Start Genetics, Inc. Screening for structural variants
ES2788737T3 (es) 2015-09-18 2020-10-22 Vanadis Diagnostics Conjunto de sondas para analizar una muestra de ADN y método para usar el mismo
WO2018015318A1 (en) 2016-07-18 2018-01-25 F. Hoffmann-La Roche Ag Method for generating single-stranded circular dna libraries for single molecule sequencing
GB201621514D0 (en) 2016-12-16 2017-02-01 Q-Linea Ab Padlock probe detection method
EP3601610A1 (en) 2017-03-30 2020-02-05 Pioneer Hi-Bred International, Inc. Methods of identifying and characterizing gene editing variations in nucleic acids
EP4589017A3 (en) 2017-10-06 2025-10-08 10x Genomics, Inc. Rna templated ligation
WO2021113290A1 (en) 2019-12-03 2021-06-10 Alamar Biosciences, Inc. Nucleic acid linked immune-sandwich assay (nulisa)
GB201919032D0 (en) 2019-12-20 2020-02-05 Cartana Ab Method of detecting an analyte
GB201919029D0 (en) 2019-12-20 2020-02-05 Cartana Ab Method of detecting an analyte
CA3178255A1 (en) * 2020-05-15 2021-11-18 Krishna KANNAN On demand synthesis of polynucleotide sequences
US12371743B2 (en) 2022-03-04 2025-07-29 Element Biosciences, Inc. Double-stranded splint adaptors and methods of use
US12469162B2 (en) 2020-08-31 2025-11-11 Element Biosciences, Inc. Primary analysis in next generation sequencing
US12359193B2 (en) 2022-03-04 2025-07-15 Element Biosciences, Inc. Single-stranded splint strands and methods of use
CA3267226A1 (en) 2022-09-12 2024-03-21 Element Biosciences, Inc. DOUBLE STRAND TO STRAND SPLINT ADAPTERS, UNIVERSAL LONG SPLINTS AND METHODS OF USE

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0826244B2 (ja) * 1988-10-21 1996-03-13 東洋インキ製造株式会社 ジスアゾ顔料組成物および印刷インキ組成物
US5882856A (en) 1995-06-07 1999-03-16 Genzyme Corporation Universal primer sequence for multiplex DNA amplification
US5994068A (en) 1997-03-11 1999-11-30 Wisconsin Alumni Research Foundation Nucleic acid indexing
WO1999049079A1 (en) 1998-03-25 1999-09-30 Ulf Landegren Rolling circle replication of padlock probes
JP2002528096A (ja) * 1998-10-27 2002-09-03 アフィメトリックス インコーポレイテッド ゲノムｄｎａの複雑性制御および分析
NO986133D0 (no) * 1998-12-23 1998-12-23 Preben Lexow FremgangsmÕte for DNA-sekvensering
US6274320B1 (en) 1999-09-16 2001-08-14 Curagen Corporation Method of sequencing a nucleic acid
US6706476B1 (en) 2000-08-22 2004-03-16 Azign Bioscience A/S Process for amplifying and labeling single stranded cDNA by 5′ ligated adaptor mediated amplification
US20040259892A1 (en) * 2001-06-29 2004-12-23 Alain Moussy Use of tyrosine kinase inhibitors for treating multiple sclerosis (ms)
GB2378245A (en) 2001-08-03 2003-02-05 Mats Nilsson Nucleic acid amplification method
GB2382137A (en) 2001-11-20 2003-05-21 Mats Gullberg Nucleic acid enrichment
EP1350853A1 (en) * 2002-04-05 2003-10-08 ID-Lelystad, Instituut voor Dierhouderij en Diergezondheid B.V. Detection of polymorphisms
US6815167B2 (en) * 2002-04-25 2004-11-09 Geneohm Sciences Amplification of DNA to produce single-stranded product of defined sequence and length
WO2003093504A1 (de) * 2002-05-06 2003-11-13 Noxxon Pharma Ag Verfahren zur amplifikation von nukleinsäuren
US8394944B2 (en) * 2002-09-20 2013-03-12 Siemens Healthcare Diagnostics Inc. Dual-purpose primers and probes for providing enhanced hybridization assays by disruption of secondary structure formation
US20040086892A1 (en) * 2002-11-06 2004-05-06 Crothers Donald M. Universal tag assay
JP3923917B2 (ja) * 2003-03-26 2007-06-06 株式会社東芝 ターゲットの製造方法、標的配列検出方法、ターゲットおよび標的配列検出用アッセイキット

Also Published As

Publication number Publication date
US7883849B1 (en) 2011-02-08
JP2007537751A (ja) 2007-12-27
WO2005111236A1 (en) 2005-11-24
EP1747285B1 (en) 2016-10-12
SE0401270D0 (sv) 2004-05-18
EP1747285A1 (en) 2007-01-31

Similar Documents

Publication Publication Date Title
JP5140425B2 (ja) 特定の核酸を同時に増幅する方法
US10900068B2 (en) Methods and systems for solution based sequence enrichment
US8986958B2 (en) Methods for generating target specific probes for solution based capture
US9745614B2 (en) Reduced representation bisulfite sequencing with diversity adaptors
CN106555226B (zh) 一种构建高通量测序文库的方法和试剂盒
US9206473B2 (en) Methods for rapid production of double-stranded target DNA
EP2494069B1 (en) Method for detecting balanced chromosomal aberrations in a genome
US20040126760A1 (en) Novel compositions and methods for carrying out multple pcr reactions on a single sample
CN102124126A (zh) 使用非随机引物的cdna合成
CN102203273A (zh) 生成基因特异性的文库的方法
EP1047794A2 (en) Method for the detection or nucleic acid of nucleic acid sequences
WO2001088174A1 (en) Novel compositions and methods for carrying out multiple pcr reactions on a single sample
WO2018081666A1 (en) Methods of single dna/rna molecule counting
CN114929896A (zh) 用于多重靶扩增pcr的有效方法和组合物
WO2022140793A1 (en) Compositions and methods for highly sensitive detection of target sequences in multiplex reactions
JP4755973B2 (ja) Ｄｎａ断片を製造する方法およびその適用
HK40064064A (en) Molecular tagging methods and sequencing libraries
JP2019176860A (ja) アセンブラ配列を利用する断片化された標的核酸の増幅方法
HK40019906B (zh) 钩状探针、核酸连接方法以及测序文库的构建方法

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080321

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20080321

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080321

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20080321

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110301

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110526

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110602

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110629

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110706

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110725

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110801

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110901

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120327

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120622

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120629

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120927

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20121023

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20121119

R150 Certificate of patent or registration of utility model

Ref document number: 5140425

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20151122

Year of fee payment: 3

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

EXPY Cancellation because of completion of term