JP5136848B2 - Infusion tube and infusion set - Google Patents

Description

The present invention also relates infusion such as nutrients and liquid medicine (intravenous fluid) infusion sets used when administered to a patient, and the drip chamber which may be preferably used in this infusion set.

  When an infusion is administered to a patient, as shown in FIG. 13, an infusion set 930 connects the infusion bag 910 storing the infusion and the patient (arm) 920. The infusion set 930 includes a bottle needle 931 that is pierced into the port 911 of the infusion bag 910, a drip tube 932 that allows the flow rate of the drip solution to be visually confirmed, a clamp 933 for adjusting the drip solution flow rate, A venous needle 934 that punctures the vein of the patient 920, a first tube 935a that connects the bottle needle 931 and the drip tube 932, a second tube 935b that connects the drip tube 932 and the clamp 933, a clamp 933, and a venous needle 934 And a third tube 935c for connecting the two.

  Infusion is generally performed according to the following procedure. First, the bottle needle 931 of the infusion set 930 is punctured into the port 911 of the infusion bag 910 with the clamp 933 closed. Next, the infusion bag 910 is suspended from the hanger 950. Then, the clamp 933 is opened to perform priming. Priming refers to an operation for introducing a drip solution to the venous needle 934. When the clamp 933 is opened, the drip in the infusion bag 910 passes through the first tube 935a, the drip tube 932, the second tube 935b, the clamp 933, and the third tube 935c in order by gravity. When the drip solution reaches the venous needle 934, the clamp 933 is closed again.

  By simply opening the clamp 933, the air that was previously in the infusion tube 932 is hardly released out of the infusion set 930, and therefore the infusion solution is hardly stored in the infusion tube 932. Therefore, an operation for storing a drip solution of about half of its volume in the drip tube 932 is performed. As this operation, a pumping method, an inverted method, and the like are often performed. In the pumping method, by closing the clamp 933 and crushing the drip tube 932, a part of the air in the drip tube 932 is moved into the infusion bag 910 through the first tube 935a, and instead, the drip solution is moved into the drip tube 932. It is an operation to be introduced. In the inversion method, the drip tube 932 is turned upside down while the drip solution is introduced into the infusion set 930 by opening the clamp 933, so that a part of the air in the drip tube 932 is moved to the second tube 935b side. This is an operation of moving to the infusion set 930 through the venous needle 934.

  When the priming is finished, the clamp 933 is closed again and the vein needle 934 is punctured into the vein of the patient 920. Then, the clamp 933 is opened, and the drip solution is administered to the patient 920. When the infusion solution in a plurality of infusion bags 910 is continuously administered to the patient 920, the clamp 933 is closed in the middle of the infusion, the bottle needle 931 is re-stabbed from the old infusion bag 910 to the new infusion bag 910, and then Open clamp 933 and continue infusion.

  When all of the drip solution in the infusion set 930 has flowed out, the air remaining in the infusion bag 910 then flows into the infusion set 930. This must be prevented in any way because it is dangerous for air to enter the veins of the patient 920.

  Various proposals have been made for such demands.

Patent Document 1 and Patent Document 2 describe an infusion tube containing a float valve. When the drip liquid is stored in the drip cylinder, the float valve floats on the drip liquid level. It fits into the outlet and closes it. This prevents air from flowing into the tube on the downstream side (patient side) of the drip tube.
Japanese Utility Model Publication No. 62-122649 Japanese Patent Laid-Open No. 2001-224683

  However, in the methods of Patent Document 1 and Patent Document 2, for example, when the drip cylinder is tilted, the float valve cannot be fitted into the drip liquid outlet or is inclined, so that the drip liquid outlet is surely secured. May not be able to block. Further, if the processing accuracy of the fitting portion between the float valve and the drip liquid outlet is low, a gap is generated between the float valve and the drip liquid outlet, and air passes through this gap. Accordingly, it is difficult to stably and reliably prevent air from flowing into the tube on the downstream side (patient side) of the drip tube.

The present invention is to solve the above conventional problems, and an object thereof is to provide a body of the patient reliably drop tube that it Ru can be prevented from flowing air, and the infusion set.

The drip tube of the present invention is provided so as to protrude into the storage part above the storage part, an air inflow prevention device provided on the side into which the drip liquid flows, a storage part in which the drip liquid is stored, and A drip cylinder having a drip liquid lower cylinder, wherein the air inflow prevention device communicates the first chamber and the second chamber through which the drip liquid passes, and the first chamber and the second chamber. A flow path, a second flow path, a hydrophilic filter provided so as to close the first flow path, and an operation unit for opening the second flow path, wherein the second flow path It is opened only when the unit is operated, and when the second flow path is opened, both air and drip liquid can move between the first chamber and the second chamber along the second flow path. der is, the infusion liquid drip tube is characterized in that it communicates with said second chamber and said reservoir.

Infusion set of the present invention comprises a drip chamber above SL of the present invention.

  According to the present invention, unless the operation part is operated, the drip liquid in the first chamber always passes through the first flow path and flows into the second chamber. At this time, since the hydrophilic filter provided in the first flow path prevents the passage of air, air does not flow into the second chamber from the first chamber. Therefore, it is possible to reliably prevent air from flowing into the patient's body.

In the drip tube of the present invention, the hydrophilic filter is preferably a flat membrane filter having a pore diameter of 5 to 15 μm. When the pore diameter is within this numerical range, it becomes easy to obtain the characteristic of preventing the passage of air when the hydrophilic filter is wet while securing the flow rate (flow velocity) necessary for the drip. Further, since the hydrophilic filter is a flat membrane filter, the hydrophilic filter can be produced at low cost.

  It is preferable that the hydrophilic filter is made of PTFE subjected to hydrophilic treatment. Accordingly, it is possible to easily realize a hydrophilic filter having a characteristic that allows both air and liquid to pass through in a dry state but does not allow air to pass through when wet and allows liquid to pass therethrough.

  It is preferable that a vent hole communicating with the outside world is provided in the first chamber, and a hydrophobic filter is provided in the vent hole. Thereby, the air in the first chamber can be easily discharged out of the infusion set during priming or when the infusion bag is replaced.

  Hereinafter, preferred embodiments of the present invention will be described with reference to the drawings. However, it goes without saying that the present invention is not limited to the following embodiments.

(Embodiment 1)
FIG. 1 is a perspective view showing a schematic configuration of an infusion tube 51 according to Embodiment 1 of the present invention. 2A is a cross-sectional view of the drip tube 51 taken along line 2A-2A in FIG. 1, and FIG. 2B is a cross-sectional view of the drip tube 51 taken along line 2B-2B in FIG. In the following description, the upper side of the paper surface of FIGS. 2A and 2B is referred to as the upper side of the drip tube 51, and the lower side of the paper surface of FIGS. 2A and 2B is referred to as the lower side of the drip tube 51. The drip tube 51 is arranged in a posture as shown in FIGS. 2A and 2B in a normal use state. The cut surface of FIG. 2A and the cut surface of FIG. 2B are orthogonal to each other at the central axis (not shown) of the drip tube 51 parallel to the vertical direction. Although the drip tube 51 may be configured using a transparent material, the internal structure of the drip tube 51 is not shown in FIG. 1 in order to simplify the drawing.

  The drip tube 51 is integrally provided with an air inflow prevention device 100 on the side into which the drip liquid flows.

  As shown in FIGS. 2A and 2B, the inside of the air inflow prevention device 100 is divided into a first chamber 101, a second chamber 102, and a third chamber 103. The first chamber 101 is separated from the second chamber 102 and the third chamber 103 by a separation wall 121 of the separation member 120. The second chamber 102 and the third chamber 103 are separated by a partition wall 125 of the separation member 120.

  The first chamber 101 located above the separation wall 121 is surrounded by the cap 110 and the separation member 120. The second chamber 102 located below the separation wall 121 is surrounded by the separation member 120 and the connecting member 130. The third chamber 103 located below the separation wall 121 and surrounding the second chamber 102 is surrounded by the cap 110, the separation member 120, and the connecting member 130.

  The drip tube 51 includes a storage unit 61 that stores drip liquid on the lower side of the air inflow prevention device 100 in the same manner as a conventionally known drip tube. The storage part 61 is surrounded by the connecting member 130 and the main cylinder 60.

  The cap 110 includes a cylindrical portion 111 having a substantially cylindrical shape, and a substantially disc-shaped top plate 112 provided at the upper end of the cylindrical portion 111. An opening 113 is formed at the center of the top plate 112, and a vent hole 118 is formed at a position slightly away from the opening 113 of the top plate 112. Both the opening 113 and the vent hole 118 are through holes that penetrate the top plate 112. A hollow cylindrical inlet 114 is erected on the edge of the opening 113 of the top plate 112 so as to protrude toward the opposite side of the cylindrical portion 111. The inflow port 114 is in communication with the first chamber 101. A tube of an infusion set (not shown, for example, the first tube 935a in FIG. 13) is connected to the inflow port 114, and an infusion solution is supplied into the infusion tube 51 (more specifically, the first chamber 101) through this. Inflow.

  A pair of operation portions 115 a and 115 b are provided symmetrically with the central axis of the drip tube 51. The operation units 115a and 115b include gripping portions 116a and 116b and ribs 117a and 117b. The gripping portions 116 a and 116 b protrude substantially parallel to the inflow port 114 toward the opposite side of the cylindrical portion 111 from the top plate 112. The ribs 117 a and 117 b are hook-like protrusions that are continuous with the gripping portions 116 a and 116 b and extend vertically on the outer peripheral surface of the cylindrical portion 111. The gripping portions 116a and 116b and the ribs 117a and 117b are connected at connection points 118a and 118b. The connection points 118 a and 118 b are located on the outer peripheral edge of the top plate 112.

  The material of the cap 110 is not particularly limited, but is preferably a material that can elastically deform the cylindrical portion 111 by operating the pair of operation portions 115a and 115b, as will be described later. Furthermore, it is preferable that the first chamber 101, the second chamber 102, and the third chamber 103 have transparency that allows the first chamber 101, the second chamber 102, and the third chamber 103 to be seen through. Specifically, for example, polycarbonate, polypropylene or the like can be used.

  A hydrophobic filter 119 is fixed to the top plate 112 so as to close the vent hole 118. The hydrophobic filter 119 has hydrophobicity and air permeability. That is, the liquid does not pass but the gas passes. Furthermore, it is preferable that the water pressure resistance measured by the water pressure resistance test specified in the method B of JIS L 1092 is 0.01 MPa or more, more preferably 0.1 MPa or more. The material of the hydrophobic filter 119 is not particularly limited, and examples thereof include polytetrafluoroethylene (PTFE), polyolefin (polypropylene, polyethylene, etc.), and polyvinylidene fluoride. The hydrophobic filter 119 is preferably a flat membrane filter such as a porous layer or a nonwoven fabric using these materials. A method for joining the hydrophobic filter 119 to the peripheral edge of the vent hole 118 is not particularly limited, but a known method such as a heat sealing method can be appropriately selected and used.

  The separation member 120 includes a substantially disc-shaped separation wall 121 and a substantially cylindrical partition wall 125 provided on the lower surface of the separation wall 121. The outer diameter of the separation wall 121 and the inner diameter of the cylindrical portion 111 of the cap 110 are substantially the same. Therefore, when the pair of operation portions 115a and 115b are not operated, the outer peripheral surface of the separation wall 121 and the inner peripheral surface of the cylindrical portion 111 are in close contact so that air or drip liquid cannot pass through. .

  A substantially circular first communication hole 122 is formed substantially at the center of the separation wall 121. The first communication hole 122 allows the first chamber 101 and the second chamber 102 that are divided by the separation wall 121 to communicate with each other.

  A hydrophilic filter 140 is attached to the lower surface of the separation wall 121 so as to close the first communication hole 122. Since the hydrophilic filter 140 has a hydrophilic treatment on the surface thereof, it has a characteristic of allowing both air and liquid to pass through in a dry state, but not allowing air to pass through in a wet state and allowing liquid to pass through. doing. The material of the hydrophilic filter 140 is not particularly limited, and polytetrafluoroethylene (PTFE), polyolefin (polypropylene, polyethylene, etc.), polyvinylidene fluoride, and the like can be used. The hydrophilic filter 140 is preferably a flat membrane filter such as a porous layer or a nonwoven fabric using these materials. This is because flat membrane filters are generally cheaper than hollow fiber filters. The hydrophilic filter 140 has a large number of fine pores, and the pore diameter is not particularly limited, but is preferably 5 to 15 μm, more preferably 8 to 10 μm. When the pore diameter is smaller than the lower limit of this numerical range, the resistance when the drip liquid passes increases, so the upper limit of the flow rate of the drip liquid that can pass through the air inflow prevention device 100 becomes lower. If the pore diameter is larger than the upper limit of this numerical range, there is a high possibility that air will pass through the hydrophilic filter 140 even when wet. As such a hydrophilic filter, for example, a hydrophilic PTFE membrane filter JCWP01300 manufactured by Millipore Corporation can be used. A method for attaching the hydrophilic filter 140 to the separation wall 121 is not particularly limited, but a known method such as a heat sealing method can be appropriately selected and used.

  The partition wall 125 is formed with a pair of notches 126a and 126b at positions facing each other. The notches 126 a and 126 b have a predetermined depth from the lower end of the partition wall 125 toward the separation wall 121.

  The connecting member 130 has a connecting cylinder 131 having a substantially cylindrical shape. The lower end of the cap 110 is extrapolated to the upper part of the connecting cylinder 131, and the upper end of the main cylinder 60 is extrapolated to the lower part of the connecting cylinder 131. It is preferable to provide an annular protrusion 132 that is continuous in the circumferential direction on the outer peripheral surface of the connecting cylinder 131 because the insertion depth of the cap 110 and the main cylinder 60 with respect to the connecting cylinder 131 can be defined using this. The connection cylinder 131 and the cap 110 are, for example, a heat seal method or a fitting method (a sealing method or a fitting method) so that no gap is formed between the connection cylinder 131 and the cap 110 when the pair of operation portions 115a and 115b are operated. That is, it is preferable that they are connected by a known method such as simple fitting. Further, the connecting cylinder 131 and the main cylinder 60 can be connected by a known method such as a heat sealing method or a fitting method (that is, simple fitting).

  A substantially disc-shaped dividing plate 133 is connected to the upper end of the connecting cylinder 131. At the center of the dividing plate 133, a hollow cylindrical drip droplet lower tube 134 is formed so as to protrude into the storage portion 61. The drip droplet lower tube 134 allows the second chamber 102 and the storage unit 61 to communicate with each other. The drip liquid flowing into the second chamber 102 flows into the reservoir 61 through the drip liquid lower tube 134.

  On the upper surface of the dividing plate 133, an annular rib 136 is formed that protrudes toward the second chamber 102 so as to surround an opening communicating with the drip droplet lower tube 134. By fitting the annular rib 136 and the partition wall 125 of the separating member 120, the separating member 120 is positioned and fixed with respect to the connecting member 130. The annular rib 136 and the partition wall 125 can be connected by a known method such as a heat seal method or a fitting method (that is, simple fitting).

  The depths of the notches 126a and 126b formed in the partition wall 125 are deeper than the height of the annular rib 136 from the upper surface of the dividing plate 133. Accordingly, second communication holes 127a and 127b surrounded by the edges of the notches 126a and 126b and the annular rib 136 are formed. The second communication holes 127 a and 127 b allow the second chamber 102 and the third chamber 103 that are divided by the partition wall 125 to communicate with each other.

  The main cylinder 60 has a substantially cylindrical shape, and the lower end thereof is narrowed to form a hollow cylindrical outlet 62. The outlet 62 communicates with the reservoir 61. A tube of an infusion set (not shown, for example, the second tube 935b of FIG. 13) is connected to the outflow port 62, and the drip solution in the drip tube 51 (more specifically, the storage unit 61) is transferred to the patient through this. Spill out towards.

  The material of the separating member 120, the connecting member 130, and the main cylinder 60 is not particularly limited, but the state of the drip liquid or air in the first chamber 101, the second chamber 102, the third chamber 103, and the storage unit 61 is visually confirmed. It is preferable that the material has transparency that enables the above. Furthermore, the main cylinder 60 is preferably made of a flexible material that enables pumping for introducing the drip liquid into the reservoir 61. As materials for the separating member 120, the connecting member 130, and the main cylinder 60, for example, polypropylene, polyvinyl chloride, or the like can be used.

  Next, a flow path that enables the drip solution and / or air to move between the first chamber 101 and the second chamber 102 will be described.

  As described above, when the pair of operation portions 115a and 115b are not operated, as shown in FIGS. 2A and 2B, the outer peripheral surface of the separation wall 121 and the inner peripheral surface of the cylindrical portion 111 are in close contact with each other. . Accordingly, the first chamber 101 and the second chamber 102 communicate with each other only through the first flow path 91 that passes through the first communication hole 122 formed in the separation wall 121. However, since the first communication hole 122 is covered with the hydrophilic filter 140, when the hydrophilic filter 140 is dry, both the air and the drip liquid flow along the first channel 91 and the first chamber 101. Although it can move between the second chambers 102, only the drip solution moves between the first chamber 101 and the second chamber 102 along the first flow path 91 when the hydrophilic filter 140 is wet. Can do.

  FIG. 3 is a cross-sectional view showing the drip tube 51 when the gripping portions 116a and 116b of the pair of operation portions 115a and 115b are sandwiched with fingers so as to approach each other. The cross section of FIG. 3 is along the same cross section as FIG. 2A. When the gripping portions 116a and 116b are brought close to each other, the pair of operation portions 115a and 115b rotate about the connection points 118a and 118b. Accordingly, the ribs 117a and 117b pull the tubular portion 111 outward from each other, and gaps 128a and 128b are formed between the tubular portion 111 and the separation wall 121 in the vicinity of the ribs 117a and 117b. Therefore, in addition to the first flow path 91, the first chamber 101 and the second chamber 102 are connected via a second flow path 92 that passes through the gaps 128a and 128b, the third chamber 103, and the second communication holes 127a and 127b. Communicate. Unlike the first flow path 91 provided with the hydrophilic filter 140, both the air and the drip liquid flow along the second flow path 92 in the first chamber 101 and the second chamber regardless of the dry state / wet state. 102 can be moved. When the finger is released from the gripping portions 116a and 116b, the pair of operation portions 115a and 115b is elastically restored to the original state, and the second flow path 92 is closed.

  A method of using the drip tube 51 of the first embodiment configured as described above and its operation will be described below.

  The drip tube 51 of Embodiment 1 can be used in place of a conventional drip tube. Here, the case where the drip tube 932 of the conventional infusion set 930 shown in FIG. 13 is replaced with the drip tube 51 of the first embodiment will be described. That is, the inflow port 114 of the drip tube 51 is connected to the first tube 935a, and the outflow port 62 is connected to the second tube 935b.

  Infusion can be performed, for example, by the following procedure.

  First, the bottle needle 931 of the infusion set 930 is punctured into the port 911 of the infusion bag 910 with the clamp 933 closed. Next, priming is performed. That is, the infusion bag 910 is suspended from the hanger 950 and the clamp 933 is opened. The drip solution in the infusion bag 910 flows through the first tube 935a due to gravity and flows into the first chamber 101 of the air inflow prevention device 100. Most of the air present in the first tube 935a and the first chamber 101 passes through the hydrophobic filter 119 and is discharged out of the infusion set 930 by the inflow of drip solution. Further, the remaining air passes through the micropores of the hydrophilic filter 140 until the hydrophilic filter 140 is wetted by the drip liquid, and finally passes through the second chamber 102 and the drip liquid lower tube 134. Is released from the infusion set 930 from the venous needle 934. Therefore, the first tube 935a and the first chamber 101 are almost filled with the drip liquid. Since the hydrophobic filter 119 does not allow liquid to pass through, the drip liquid does not leak through the hydrophobic filter 119 to the outside. Thereafter, the drip solution passes through the micropores of the hydrophilic filter 140 and flows into the storage unit 61 through the second chamber 102 and the drip droplet lower tube 134. The drip liquid that has flowed into the reservoir 61 flows into the second tube 935b, the clamp 933, and the third tube 935c in this order by gravity. When the drip solution reaches the venous needle 934, the clamp 933 is closed.

  During the above priming, the second flow path 92 may be formed by sandwiching the gripping portions 116a and 116b with fingers so as to approach each other as shown in FIG. The second flow path 92 has a lower flow resistance of the drip liquid than the first flow path 91 that must pass through the hydrophilic filter 140. Accordingly, since the flow rate of the drip solution can be increased by passing the drip solution through the second flow path 92, the time required for priming can be shortened.

  Similar to the conventional priming operation, it is necessary to perform an operation for storing the drip liquid of about half of its capacity in the storage part 61 of the drip tube 51. As this operation, a pumping method, an inversion method, and the like can be performed as in the conventional case.

  The pumping method will be described. By simply opening the clamp 933 and introducing the infusion solution in the infusion bag 910 into the infusion set 930, the infusion solution 10 is contained in the first tube 935a, the first chamber 101, and the second tube as shown in FIG. Although 935b is filled, it may be hardly stored in the storage unit 61. Therefore, the clamp 933 is closed, and the second flow path 92 is formed by sandwiching the grip portions 116a and 116b of the pair of operation portions 115a and 115b with fingers so as to approach each other (see FIG. 3). Then, the air in the second chamber 102 and the third chamber 103 passes through the second flow path 92 and moves into the first chamber 101, and instead, the drip liquid in the first chamber 101 is transferred to the second chamber 102 and the second chamber 102. It flows into the three chambers 103. Further, as shown in FIG. 5, the main cylinder 60 is crushed in a state where the second flow path 92 is formed, and the internal volume of the storage portion 61 is reduced. Since the clamp 933 on the outflow port 62 side is closed, the air in the reservoir 61 that has lost the escape space becomes the bubble 11, and sequentially passes through the drip droplet lower tube 134, the second chamber 102, and the second flow path 92. Then, it flows into the first chamber 101. Furthermore, the bubbles 11 move into the infusion bag 910 through the first tube 935a. Thereafter, the fingers are removed from the gripping portions 116a and 116b, and the second flow path 92 is closed. Then, when the compression force to the main cylinder 60 is released, the main cylinder 60 is elastically restored to the state before compression, the inside of the storage section 61 becomes negative pressure, and the drip liquid in the first chamber 101 becomes the hydrophilic filter 140, the first The two chambers 102 and the drip droplet lower tube 134 are sequentially passed through the storage unit 61. By repeating the operation of crushing the main cylinder 60 several times, as shown in FIG. 6, approximately 1/3 to 1/2 of the internal volume of the reservoir 61 is stored in the reservoir 61. Can do.

  In the above pumping method, instead of crushing the main tube 60 as shown in FIG. 5, a light impact is applied to the main tube portion 60 by flipping the main tube portion 60 with a finger in a state where the second flow path 92 is formed. May be added. Thereby, similarly to the case of FIG. 5, the air in the reservoir 61 can be moved into the infusion bag 910 via the second flow path 92, and the drip solution 10 can be allowed to flow into the reservoir 61 instead.

  Explain the inverted method. In the inverted method, the drip tube 51 is turned upside down at a position lower than the infusion bag 910 while the infusion set 930 is being introduced into the infusion set 930 by opening the clamp 933 as in the prior art. Thereby, the air in the storage part 61 passes the outflow port 62 in a position higher than this, and flows out into the 2nd tube 935b. At the same time, a drip liquid corresponding to the amount of air flowing out to the second tube 935 b flows into the storage unit 61 from the second chamber 102 through the drip liquid lower tube 134 and is stored in the storage unit 61. When the drip liquid of a desired amount flows into the storage unit 61, the posture of the drip tube 51 is returned to the original position, so that approximately 1/3 to 1/2 of the internal volume of the storage unit 61 as shown in FIG. This drip solution can be stored in the storage unit 61. Since the hydrophobic filter 119 does not allow liquid to pass, even if the position of the drip tube 51 is turned upside down, the drip liquid does not pass through the hydrophobic filter 119 and leak to the outside.

  As described above, the drip tube 51 of the first embodiment is hardly different from the conventional drip tube 933 with respect to the priming operation.

  When the priming is completed, the clamp 933 is closed again and the venous needle 934 is punctured into the vein of the patient 920 as in the conventional case. Then, the clamp 933 is opened, and the drip solution is administered to the patient 920. At this time, since the second flow path 92 is closed, the drip solution passes through many fine holes of the hydrophilic filter 140 covering the first flow path 91 and reaches the patient's body. In the first embodiment, the opening diameter of the first communication hole 122 that forms the first flow path 91 and the hole diameter of the fine holes formed in the hydrophilic filter 140 that covers the first flow path 91 are appropriately set. Thus, it is possible to easily secure a flow rate (flow velocity) required during infusion.

  When all of the drip solution in the infusion bag 910 has flowed out, the air remaining in the infusion bag 910 then flows into the infusion set 930. FIG. 7 shows a state in which the drip liquid in the first tube 935a and the first chamber 101 is almost completely replaced with air. Due to the gravity acting on the drip solution 10 in the portion of the infusion set 930 on the downstream side of the reservoir 61, the air layer 13 in the reservoir 61 becomes negative pressure. However, since the hydrophilic filter 140 is in a wet state, the air in the first chamber 101 cannot pass through the hydrophilic filter 140 and move into the second chamber 102. The second flow path 92 (see FIG. 3) is closed. Accordingly, the gravity acting on the drip solution 10 in the portion of the infusion set 930 downstream of the storage unit 61 balances with the negative pressure of the air layer 13 in the storage unit 61 so that the drip solution 10 is more on the patient side. Is prevented from moving to. Therefore, air does not flow into the patient's body.

  Next, the case where the infusion solution in the plurality of infusion bags 910 is continuously administered to the patient 920 will be described.

  When all the drip solution in the first infusion bag 910 has flowed out, the first tube 935a and the first chamber 101 are almost filled with air as shown in FIG. About half of the volume of drip is stored. Further, the portion from the second tube 935b to the venous needle 934 of the infusion set 930 is filled with the drip solution. The venous needle 934 remains pierced by the patient 920. In this state, first, the clamp 933 is closed. Next, the bottle needle 931 is extracted from the port 911 of the first infusion bag 910 that is emptied and punctured into the port 911 of the second infusion bag 910 filled with the drip solution. When the second infusion bag 910 is hung on the hanger 950, the drip in the second infusion bag 910 flows in the first tube 935a by gravity and flows into the first chamber 101 of the infusion tube 51. . At this time, most of the air existing in the first tube 935a and the first chamber 101 passes through the hydrophobic filter 119 (see FIG. 2B) and is discharged out of the infusion set 930 by the inflow of the drip solution. The first tube 935a and the first chamber 101 are almost filled with the drip liquid. Thereafter, the clamp 933 is opened to start infusion. Furthermore, when performing the drip of the third and subsequent infusion bags 910, the above operation may be repeated.

  As described above, when the drip tube 51 of the first embodiment is used, even when the drip of the first infusion bag 910 is completed, the portion downstream of the second tube 935b of the infusion set 930 is filled with the drip solution. Since the maintained state is maintained, the infusion can be continuously performed by simply replacing the bottle needle 931 with the second infusion bag 910 without performing the priming operation again.

  In addition, as described above, in the drip tube 51 of the first embodiment, even when the drip of the first infusion bag 910 is finished, air is mixed into the downstream portion of the second tube 935b of the infusion set 930. Can be surely prevented. Conventionally, in order to release the air mixed in the portion downstream of the second tube 935b of the infusion set 930 to the outside of the infusion set 930, the venous needle 934 is once removed from the patient 920 or the complicated work is required. Had to do. If the drip tube 51 of the first embodiment is used, this problem is solved, and the bottle needle 931 is continuously inserted by simply replacing the empty infusion bag 910 with a new infusion bag 910 while the venous needle 934 is punctured into the patient 920. Infusion can be performed. Therefore, the safety of the infusion is improved, the infusion time is shortened, and the work burden on the nurse who performs the infusion is further reduced.

  Furthermore, since the drip tube 51 is integrally provided with the air inflow prevention device 100, the drip tube having the air inflow prevention function can be configured in a small size. Moreover, the number of parts which comprise an infusion set can be reduced.

  In the first embodiment, the pair of operation units may be configured such that the gripping portions 116a and 116b are positioned below the ribs 117a and 117b.

(Embodiment 2)
FIG. 8 is a perspective view showing a schematic configuration of the drip tube 52 according to the second embodiment of the present invention. The drip tube 52 of Embodiment 2 includes a pair of operation units 215a and 215b provided along a plane orthogonal to the central axis of the drip tube 52 as an operation unit for opening and closing the second flow path. The infusion tube 51 is different from the infusion tube 51 of the first embodiment provided with a pair of operation portions 115a and 115b provided along a plane including the central axis of the infusion tube 51. In the drip tube 52, members having the same functions as those of the drip tube 51 of the first embodiment are denoted by the same reference numerals, and description thereof is omitted.

  9A is a cross-sectional view of the drip tube along line 9A-9A in FIG. 8 including a pair of operation portions 215a and 215b.

  As shown in FIGS. 8 and 9A, the operation units 215a and 215b include gripping units 216a and 216b and ribs 217a and 217b. The grip portions 216 a and 216 b protrude from the outer peripheral surface of the cylindrical portion 111. The ribs 217a and 217b are hook-like protrusions that are continuous with the grip portions 216a and 216b and extend on the outer peripheral surface of the cylindrical portion 111 along the circumferential direction. In the vertical direction, the gripping portions 216 a and 216 b are disposed at substantially the same height as the separation wall 121. When the gripping portions 216a and 216b of the pair of operation portions 215a and 215b are pinched with fingers so as to approach each other, the cylindrical portion 111 is elastically deformed, and as shown in FIG. 9B, the cylindrical portion 111 and the separation wall 121 are separated. A gap 228 constituting the second flow path is formed therebetween. Accordingly, the first chamber 101 and the second chamber 102 include the gap 228, the third chamber 103, and the second communication holes 127a and 127b (see FIG. 2A) in addition to the first flow path 91 described in the first embodiment. Through a second flow path that passes through

  The second embodiment is the same as the first embodiment except for the above.

(Embodiment 3)
In the first and second embodiments, the drip cylinders 51 and 52 in which the air inflow prevention device 100 is integrally provided are shown. However, the air inflow prevention device of the present invention may be separated from the drip cylinder. FIG. 10 is a perspective view showing an air inflow prevention device 300 according to Embodiment 3 of the present invention in which a drip tube is not attached, and FIG. 11A is a cross section of the air inflow prevention device 300 taken along line 11A-11A in FIG. 11 and 11B are cross-sectional views of the air inflow preventing device 300 taken along the line 11B-11B in FIG. In these drawings, members having the same functions as those in FIGS. 1, 2A, and 2B are denoted by the same reference numerals. An outflow pipe 334 communicates with the second chamber 92. The air inflow prevention device 300 of Embodiment 3 has substantially the same configuration as the air inflow prevention device 100 obtained by removing the main tube 60 from the drip tube 51 of Embodiment 1, and is the same as the air inflow prevention device 100. Can function.

  The air inflow prevention device 300 can be used by being incorporated in a conventional well-known infusion set. For example, when the air inflow prevention device 300 is incorporated into the conventional infusion set 930 shown in FIG. 13, there are two types depending on which of the air inflow prevention device 300 and the drip tube 932 is arranged on the upstream side (infusion bag 910 side). A connection form is conceivable. When the air inflow prevention device 300 is arranged on the upstream side of the drip tube 932, for example, the first tube 935a is connected to the inlet 114 of the air inflow prevention device 300, and the outflow pipe 334 of the air inflow prevention device 300 and the drip tube are connected. The inflow pipe 932a of 932 can be connected by a tube (not shown). On the other hand, when the drip tube 932 is disposed upstream of the air inflow prevention device 300, the outflow port 932b of the drip tube 932 and the inflow port 114 of the air inflow prevention device 300 are connected by a tube (not shown), and the air The second tube 935 b can be connected to the outflow pipe 334 of the inflow prevention device 300.

  Of the two connection forms as described above, in general, the air inflow prevention device 300 is preferably disposed on the upstream side of the drip tube 932. The reason is as follows.

  As described above, the air inflow prevention device 300 according to the third embodiment prevents the inflow of air to the downstream side unless the second flow path 92 is opened by operating the pair of operation units 115a and 115b. To do. Therefore, when the air inflow prevention device 300 is arranged on the upstream side of the infusion tube 932, even if all of the infusion solution in the infusion bag 910 flows out, the inside of the infusion tube 932 is the same as described in FIG. In the state where about half of the volume of the drip liquid has been stored, the flow of the drip liquid stops. Therefore, in the case where the infusion solutions in the plurality of infusion bags 910 are continuously administered to the patient 920, the infusion is continuously performed without replacing the bottle needle 931 with another new infusion bag 910 and performing the priming operation again. Can be done automatically.

  On the other hand, when the drip tube 932 is arranged on the upstream side of the air inflow prevention device 300, if all of the drip liquid in the infusion bag 910 flows out, the drip tube on the upstream side of the air inflow prevention device 300. All the drip solution in 932 will flow out. Therefore, in the case where the infusion solution in a plurality of infusion bags 910 is continuously administered to the patient 920, the bottle needle 931 is replaced with another new infusion bag 910 and then the infusion tube 932 has about half of its capacity. In order to store the drip solution, it is necessary to perform the above-described pumping method, inversion method, and the like. Furthermore, when performing the pumping method, it is necessary to close the clamp 933. Therefore, when the drip is restarted, it is necessary to readjust the opening of the clamp 933 to obtain an appropriate flow rate of the drip solution. As described above, when the drip tube 932 is arranged on the upstream side of the air inflow prevention device 300, when the drip solution in the plurality of infusion bags is continuously administered to the patient, the working efficiency is lowered.

  Therefore, the air inflow prevention device 300 is preferably disposed on the upstream side of the drip tube 932.

  Said Embodiment 1-3 is only an example, and this invention is not limited to said Embodiment 1-3, A various change is possible.

  For example, the vent 118 and the hydrophobic filter 119 can be omitted in the first embodiment.

  In this case, in priming, the air present in the first tube 935a and the first chamber 101 passes through the micropores of the hydrophilic filter 140, passes through the second chamber 102 and the drip droplet lower tube 134, and finally. Specifically, the fluid is discharged from the intravenous needle 934 to the outside of the infusion set 930. If the hydrophilic filter 140 gets wet with the drip solution, air cannot pass through the hydrophilic filter 140, so that there may be a case where a little air remains in the first chamber 101. However, even if air remains in the first chamber 101, the air cannot pass through the wet hydrophilic filter 140 and therefore does not flow into the patient's body.

  Further, when the vent 118 and the hydrophobic filter 119 are omitted, it is preferable to perform, for example, the following operation when replacing the empty infusion bag 910 with a new infusion bag 910. The clamp 933 is closed and the bottle needle 931 is replaced from the empty infusion bag 910 with a new infusion bag 910. Next, as shown in FIG. 12, the main cylinder 60 is crushed in a state where the second flow path 92 is formed by sandwiching the gripping portions 116 a and 116 b with fingers so as to reduce the internal volume of the storage portion 61. . As a result, part of the air in the first tube 935a and the first chamber 101 moves into the infusion bag 910. Thereafter, the compression force on the main cylinder 60 is released. When the main cylinder 60 is elastically restored to the state before compression, the drip solution in the infusion bag 910 flows into the first tube 935a and the first chamber 101. Thereafter, the second flow path 92 is closed. By repeating such an operation several times, at least the inside of the first tube 935a can be substantially filled with the drip solution. Thereafter, the clamp 933 is opened to start infusion. This method may not be able to completely eliminate the air from the first chamber 101. However, since the air remaining in the first chamber 101 cannot pass through the wet hydrophilic filter 140, it does not flow into the patient's body.

  Also in Embodiments 2 and 3, the vent 118 and the hydrophobic filter 119 can be omitted in the same manner as described above.

  The air inflow prevention device of the present invention only needs to have the first chamber and the second chamber through which the drip liquid passes, and the cap 110 and the separation member 120 as in the air inflow prevention devices 100 and 300 of the first to third embodiments. The connecting member 130 need not be constituted by three members. What members are combined to form the air inflow prevention device can be appropriately changed in consideration of the structure and material of the air inflow prevention device. Further, in the present invention, the second flow path that connects the first chamber and the second chamber is formed only when the operation section is operated, and the second flow path only needs to be closed when the operation section is not operated. Therefore, the path of the second flow path is not limited to the first to third embodiments. In the first to third embodiments, the pair of notches 126a and 126b are formed in the partition wall 125 in order to form the second flow path 92. However, the number of notches formed in the partition wall 125 is not necessarily two. There may be one, three or more. Moreover, the structure where the 3rd chamber 103 shown by said Embodiment 1-3 may not exist may be sufficient. Moreover, the structure of the operation part for opening and closing a 2nd flow path is not limited to what was shown in Embodiment 1-3.

  In the above first to third embodiments, the inlet 114 at the upstream end of the air inflow prevention devices 100 and 300 and the bottle needle 931 are connected by the first tube 935a, but the air inflow prevention device of the present invention is limited to this. Not. For example, a so-called bottle needle integrated air inflow prevention device (or a bottle needle and air inflow prevention device integrated drip tube) in which the bottle needle 931 is directly connected to the upstream end of the air inflow prevention device without a tube. There may be.

  In the first to third embodiments, the hydrophilic filter 140 is attached to the lower surface of the separation wall 121 so as to close the first communication hole 122, but may be attached to the upper surface of the separation wall 121. . However, when the hydrophilic filter 140 is affixed to the lower surface of the separation wall 121 as in the first to third embodiments, air hardly accumulates in the opening of the first communication hole 122 below the hydrophilic filter 140. This is preferable.

  The infusion set to which the air inflow prevention device of the present invention (or the drip tube in which the air inflow prevention device is integrated) is applied is not limited to the configuration of FIG. 13, and the air inflow prevention device of the present invention includes an infusion tube. It can be applied to various known infusion sets. The infusion set may include, for example, a co-infusion port for co-injecting a drug into the drip solution, an air reservoir for capturing air in the drip solution, a connector for connecting an extension tube, and the like.

  The field of use of the present invention is not particularly limited, but can be widely used as an infusion set and an air inflow prevention device used when administering an infusion solution (drip solution) such as a nutrient or a drug solution to a patient.

FIG. 1 is a perspective view showing a schematic configuration of an infusion tube integrally provided with an air inflow prevention device according to Embodiment 1 of the present invention. FIG. 2A is a cross-sectional view of the drip tube according to the first embodiment of the present invention along the line 2A-2A in FIG. 2B is a cross-sectional view of the drip tube according to the first embodiment of the present invention along the line 2B-2B in FIG. FIG. 3 is a cross-sectional view of the drip tube according to the first embodiment of the present invention, showing a second flow path formed when a pair of operation units is operated. FIG. 4 is a cross-sectional view showing the drip tube according to the first embodiment of the present invention during the priming operation. FIG. 5 is a cross-sectional view illustrating a pumping operation for the drip tube according to the first embodiment of the present invention. FIG. 6 is a cross-sectional view showing the drip tube according to the first embodiment of the present invention in which a predetermined amount of drip liquid is stored in the main storage part. FIG. 7 is a cross-sectional view showing an infusion tube according to Embodiment 1 of the present invention after the end of infusion. FIG. 8 is a perspective view showing a schematic configuration of an infusion tube according to Embodiment 2 of the present invention. FIG. 9A is a cross-sectional view of an infusion tube according to Embodiment 2 of the present invention, taken along line 9A-9A in FIG. FIG. 9B is a cross-sectional view showing how the second flow path is formed in the drip tube according to Embodiment 2 of the present invention. FIG. 10 is a perspective view showing a schematic configuration of an air inflow prevention device according to Embodiment 3 of the present invention. FIG. 11A is a cross-sectional view of the air inflow preventing device according to the third embodiment of the present invention along the line 11A-11A in FIG. FIG. 11B is a cross-sectional view of the air inflow preventing device according to the third embodiment of the present invention along the line 11B-11B in FIG. FIG. 12 is a cross-sectional view showing an infusion tube according to another embodiment of the present invention during a priming operation. FIG. 13 is a schematic view showing an example of a general method for administering a drip solution to a patient.

Explanation of symbols

10 drip solution 11 bubble 13 air layer 51, 52 drip tube 60 main tube 61 reservoir 62 outlet 91 first flow channel 92 second flow channel 100 air inflow prevention device 101 first chamber 102 second chamber 103 third chamber 110 Cap 111 Cylindrical part 112 Top plate 113 Opening 114 Inlet 115a, 115b Operation part 116a, 116b Gripping part 117a, 117b Rib 118a, 118b Connection point 118 Vent 119 Hydrophobic filter 120 Separation member 121 Separation wall 122 First communication hole 125 Partitions 126a and 126b Notches 127a and 127b Second communication holes 128a and 128b Gap 130 Connection member 131 Connection cylinder 132 Annular projection 133 Dividing plate 134 Droplet droplet lower cylinder 136 Annular rib 140 Hydrophilic filters 215a and 215b Operation parts 216a and 216b Grip part 217a, 217b 228 gap 300 air inflow prevention device 334 outlet pipe 910 infusion bag 911 port 920 patients 930 infusion set 931 bottle needle 932 drip chamber 933 clamp 934 venous needle 935a, 935b, 935c tube 950 Hanger

Claims (5)

An air inflow prevention device provided on the inflow side of the drip liquid, a storage part for storing the drip liquid, and a drip liquid lower cylinder provided so as to protrude into the storage part above the storage part Drip tube,
The air inflow prevention device is:
A first chamber and a second chamber through which the drip solution passes;
A first flow path and a second flow path for communicating the first chamber and the second chamber;
A hydrophilic filter provided to close the first flow path;
An operation unit for opening the second flow path,
The second flow path is opened only when the operation unit is operated,
When the second flow path is opened, Ri movable der between both air and infusion fluid along said second flow path between the first chamber and the second chamber,
The drip droplet lower tube communicates the second chamber and the storage portion with each other . The drip tube according to claim 1, wherein the hydrophilic filter is a flat membrane filter having a pore diameter of 5 to 15 μm. The drip tube according to claim 1 or 2, wherein the hydrophilic filter is made of PTFE subjected to a hydrophilic treatment. The drip tube according to any one of claims 1 to 3, wherein a vent hole communicating with the outside is provided in the first chamber, and a hydrophobic filter is provided in the vent hole. Infusion set provided with a point drop tube according to claim 1.

Images