JP5091876B2 - 癌、特に乳癌、甲状腺癌及び肺癌のインビトロ診断のためのProNGFアッセイのための方法とProNGFの治療的使用 - Google Patents

癌、特に乳癌、甲状腺癌及び肺癌のインビトロ診断のためのProNGFアッセイのための方法とProNGFの治療的使用 Download PDF

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JP5091876B2
JP5091876B2 JP2008552858A JP2008552858A JP5091876B2 JP 5091876 B2 JP5091876 B2 JP 5091876B2 JP 2008552858 A JP2008552858 A JP 2008552858A JP 2008552858 A JP2008552858 A JP 2008552858A JP 5091876 B2 JP5091876 B2 JP 5091876B2
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prongf
cancer
cells
breast
thyroid
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ジュヌヴィエーヴ ショケ−カスティルヴスキ,
ヨアン ドゥモン,
ウベール オンデルマルク,
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Biomerieux SA
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
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    • AHUMAN NECESSITIES
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    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
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    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57415Specifically defined cancers of breast
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • G01N2333/48Nerve growth factor [NGF]

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
JP2008552858A 2006-01-31 2007-01-30 癌、特に乳癌、甲状腺癌及び肺癌のインビトロ診断のためのProNGFアッセイのための方法とProNGFの治療的使用 Active JP5091876B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0600851 2006-01-31
FR0600851A FR2896881B1 (fr) 2006-01-31 2006-01-31 Procede de dosage du prongf pour le diagnostic in vitro du cancer du sein et utilisation du prongf en therapie
PCT/FR2007/050708 WO2007088305A1 (fr) 2006-01-31 2007-01-30 Procede de dosage du prongf pour le diagnostic in vitro du cancer en particulier du cancer du sein, de la thyroide ou du poumon et utilisation du prongf en therapie

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JP2012124525A Division JP5792121B2 (ja) 2006-01-31 2012-05-31 癌、特に乳癌、甲状腺癌及び肺癌のインビトロ診断のためのProNGFアッセイのための方法とProNGFの治療的使用

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JP2009525478A5 JP2009525478A5 (enExample) 2010-03-04
JP5091876B2 true JP5091876B2 (ja) 2012-12-05

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JP2008552858A Active JP5091876B2 (ja) 2006-01-31 2007-01-30 癌、特に乳癌、甲状腺癌及び肺癌のインビトロ診断のためのProNGFアッセイのための方法とProNGFの治療的使用
JP2012124525A Active JP5792121B2 (ja) 2006-01-31 2012-05-31 癌、特に乳癌、甲状腺癌及び肺癌のインビトロ診断のためのProNGFアッセイのための方法とProNGFの治療的使用

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US (3) US8008009B2 (enExample)
EP (1) EP1982192B1 (enExample)
JP (2) JP5091876B2 (enExample)
CN (2) CN101395478B (enExample)
ES (1) ES2471126T3 (enExample)
FR (1) FR2896881B1 (enExample)
WO (1) WO2007088305A1 (enExample)

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FR2896881B1 (fr) * 2006-01-31 2008-04-18 Biomerieux Sa Procede de dosage du prongf pour le diagnostic in vitro du cancer du sein et utilisation du prongf en therapie
WO2008058018A2 (en) 2006-11-02 2008-05-15 Mayo Foundation For Medical Education And Research Predicting cancer outcome
EP2806054A1 (en) 2008-05-28 2014-11-26 Genomedx Biosciences Inc. Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer
US10407731B2 (en) 2008-05-30 2019-09-10 Mayo Foundation For Medical Education And Research Biomarker panels for predicting prostate cancer outcomes
US9495515B1 (en) 2009-12-09 2016-11-15 Veracyte, Inc. Algorithms for disease diagnostics
US10236078B2 (en) 2008-11-17 2019-03-19 Veracyte, Inc. Methods for processing or analyzing a sample of thyroid tissue
US9074258B2 (en) 2009-03-04 2015-07-07 Genomedx Biosciences Inc. Compositions and methods for classifying thyroid nodule disease
FR2944019B1 (fr) * 2009-04-03 2011-04-22 Biomerieux Sa Procede de dosage de la prodefensine-a6 pour le diagnostic in vitro du cancer colorectal.
JP6078339B2 (ja) 2009-05-07 2017-02-08 ベラサイト インコーポレイテッド 甲状腺状態の診断のための方法および組成物
US10446272B2 (en) 2009-12-09 2019-10-15 Veracyte, Inc. Methods and compositions for classification of samples
CN101782585A (zh) * 2010-02-10 2010-07-21 广州医学院 肺癌组织蛋白印迹膜片及其制备方法
WO2011159762A1 (en) * 2010-06-15 2011-12-22 Cornell University Methods of limiting microvascular damage following acute myocardial ischemia
US20130267443A1 (en) 2010-11-19 2013-10-10 The Regents Of The University Of Michigan ncRNA AND USES THEREOF
JP2014521958A (ja) * 2011-07-28 2014-08-28 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 胸腔内液若しくは漿液と関連する腫瘍細胞の特徴づけによる癌の診断方法
WO2013090620A1 (en) 2011-12-13 2013-06-20 Genomedx Biosciences, Inc. Cancer diagnostics using non-coding transcripts
ES2945036T3 (es) 2012-08-16 2023-06-28 Veracyte Sd Inc Pronóstico del cáncer de próstata mediante biomarcadores
CN103122390B (zh) * 2013-03-07 2015-04-08 上海市疾病预防控制中心 Frat1基因作为检测甲状腺癌的血清标志物及其应用
US10526655B2 (en) 2013-03-14 2020-01-07 Veracyte, Inc. Methods for evaluating COPD status
US11976329B2 (en) 2013-03-15 2024-05-07 Veracyte, Inc. Methods and systems for detecting usual interstitial pneumonia
CN103866039B (zh) * 2014-04-04 2015-05-27 厦门大学 人类甲状腺癌组织基因特异位点甲基化水平检测引物及其应用
US12297505B2 (en) 2014-07-14 2025-05-13 Veracyte, Inc. Algorithms for disease diagnostics
EP2977759B1 (en) * 2014-07-25 2017-07-12 Serum Institute of India Private Limited Highly sensitive immunoassay for rapid quantification of meningococcal capsular polysaccharide antigens
EP3770274A1 (en) 2014-11-05 2021-01-27 Veracyte, Inc. Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data
LT3280441T (lt) 2015-04-07 2021-11-25 Alector Llc Anti-sortilino antikūnai ir jų naudojimo būdai
US10849992B1 (en) 2015-04-07 2020-12-01 Alector Llc Methods of screening for sortilin binding antagonists
US11414708B2 (en) 2016-08-24 2022-08-16 Decipher Biosciences, Inc. Use of genomic signatures to predict responsiveness of patients with prostate cancer to post-operative radiation therapy
AU2018210695B2 (en) 2017-01-20 2024-07-18 The University Of British Columbia Molecular subtyping, prognosis, and treatment of bladder cancer
CA3051488A1 (en) * 2017-01-24 2018-08-02 Genetic Technologies Limited Improved methods for assessing risk of developing breast cancer
US11873532B2 (en) 2017-03-09 2024-01-16 Decipher Biosciences, Inc. Subtyping prostate cancer to predict response to hormone therapy
WO2018205035A1 (en) 2017-05-12 2018-11-15 Genomedx Biosciences, Inc Genetic signatures to predict prostate cancer metastasis and identify tumor agressiveness
EP3635399B1 (fr) * 2017-06-08 2025-10-29 Gnaho, Sylvain Méthode d'isolement et de détection de cellules souches cancéreuses
US11217329B1 (en) 2017-06-23 2022-01-04 Veracyte, Inc. Methods and systems for determining biological sample integrity
PE20210186A1 (es) 2018-07-13 2021-02-02 Alector Llc Anticuerpos anti-sortilina y metodos para su uso

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US6548062B2 (en) * 2000-02-29 2003-04-15 Cephalon, Inc. Method of treating cancer with anti-neurotrophin agents
WO2003076942A2 (fr) 2002-03-13 2003-09-18 Biomerieux Quantification de cellules tumorales circulantes issues de cancers solides
FR2846426B1 (fr) * 2002-10-28 2004-12-10 Bio Merieux Procede de dosage du ngf pour le diagnostic in vitro du cancer du sein et utilisation en therapie
ATE545429T1 (de) * 2002-12-20 2012-03-15 Lundbeck & Co As H Modulation der neurotrophinaktivität;screeningsverfahren
WO2005076695A2 (en) * 2004-02-11 2005-08-25 Painceptor Pharma Corporation Methods of modulating neurotrophin-mediated activity
FR2896881B1 (fr) * 2006-01-31 2008-04-18 Biomerieux Sa Procede de dosage du prongf pour le diagnostic in vitro du cancer du sein et utilisation du prongf en therapie

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CN101395478B (zh) 2013-08-28
JP5792121B2 (ja) 2015-10-07
FR2896881B1 (fr) 2008-04-18
JP2009525478A (ja) 2009-07-09
US9061045B2 (en) 2015-06-23
WO2007088305A1 (fr) 2007-08-09
CN101395478A (zh) 2009-03-25
US20090068200A1 (en) 2009-03-12
EP1982192B1 (fr) 2014-03-26
FR2896881A1 (fr) 2007-08-03
US20110293636A1 (en) 2011-12-01
EP1982192A1 (fr) 2008-10-22
US20130171173A1 (en) 2013-07-04
ES2471126T3 (es) 2014-06-25
JP2012211148A (ja) 2012-11-01
CN103446585A (zh) 2013-12-18
US8008009B2 (en) 2011-08-30

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