JP5047442B2 - 神経保護剤としての非鎮静バルビツレート化合物 - Google Patents
神経保護剤としての非鎮静バルビツレート化合物 Download PDFInfo
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- JP5047442B2 JP5047442B2 JP2002513464A JP2002513464A JP5047442B2 JP 5047442 B2 JP5047442 B2 JP 5047442B2 JP 2002513464 A JP2002513464 A JP 2002513464A JP 2002513464 A JP2002513464 A JP 2002513464A JP 5047442 B2 JP5047442 B2 JP 5047442B2
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- lower alkyl
- pharmaceutical composition
- barbiturate
- substituted
- benzyl
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22167200P | 2000-07-26 | 2000-07-26 | |
| US60/221,672 | 2000-07-26 | ||
| PCT/US2001/023420 WO2002007729A1 (en) | 2000-07-26 | 2001-07-26 | Non-sedating barbiturate compounds as neuroprotective agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004517808A JP2004517808A (ja) | 2004-06-17 |
| JP2004517808A5 JP2004517808A5 (US07794700-20100914-C00152.png) | 2008-09-11 |
| JP5047442B2 true JP5047442B2 (ja) | 2012-10-10 |
Family
ID=22828824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002513464A Expired - Fee Related JP5047442B2 (ja) | 2000-07-26 | 2001-07-26 | 神経保護剤としての非鎮静バルビツレート化合物 |
Country Status (14)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6093820A (en) | 1997-10-02 | 2000-07-25 | Taro Pharmaceutical Industries Ltd. | Method and reagents for N-alkylating ureides |
| EP1311270B1 (en) * | 2000-07-26 | 2008-01-09 | Taro Pharmaceutical Industries Limited | Non-sedating barbiturate compounds as neuroprotective agents |
| US6756379B2 (en) | 2001-07-26 | 2004-06-29 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
| US7683071B2 (en) | 2000-07-26 | 2010-03-23 | Taro Pharmaceuticals Industries Ltd. | Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid |
| US6939873B2 (en) | 2000-07-26 | 2005-09-06 | Taro Pharmaceuticals Industries Limited | Non-sedating barbituric acid derivatives |
| CN1291720C (zh) * | 2002-01-30 | 2006-12-27 | 塔罗制药工业有限公司 | 非镇静性巴比土酸衍生物 |
| KR101403264B1 (ko) * | 2002-10-11 | 2014-06-02 | 백스터 인터내셔널 인코포레이티드 | 할로겐화된 휘발성 마취제의 정맥내 투여에 의한 심장보호 및 신경보호방법 |
| AR042444A1 (es) * | 2002-12-11 | 2005-06-22 | Taro Pharmaceuticals Ireland L | Metodo para el tratamiento de desordenes del movimiento mediante la utilizacion de acido barbiturico |
| EP1625848A1 (en) * | 2004-08-10 | 2006-02-15 | Taro Pharmaceuticals North America, Inc. | Composition and method for enhanced delivery of 5,5-diphenyl barbituric acid |
| US9056817B2 (en) * | 2011-09-12 | 2015-06-16 | Council Of Scientific And Industrial Research | Arylated β-dicarbonyl compounds and process for the preparation thereof |
| CN102863579B (zh) * | 2012-09-14 | 2014-02-05 | 东南大学 | 一种巴比妥酸螯合树脂及其制备方法和应用 |
| CN113640512A (zh) | 2015-10-05 | 2021-11-12 | 北卡罗来纳-查佩尔山大学 | 用于多路测定的解码方法及相关流体设备、试剂盒和固体支持物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL69722A (en) * | 1983-09-14 | 1986-09-30 | Taro Pharma Ind | Oxopyrimidine derivatives and pharmaceutical compositions containing them |
| US4833148A (en) * | 1987-04-09 | 1989-05-23 | Washington University | Method of using alkenyl- or alkynyl-substituted thiobarbiturates to reduce neurotoxic injury |
| US5474990A (en) * | 1989-10-20 | 1995-12-12 | Olney; John W. | Barbiturates as safening agents in conjunction with NMDA antagonists |
| EP1311270B1 (en) * | 2000-07-26 | 2008-01-09 | Taro Pharmaceutical Industries Limited | Non-sedating barbiturate compounds as neuroprotective agents |
-
2001
- 2001-07-26 EP EP01959195A patent/EP1311270B1/en not_active Expired - Lifetime
- 2001-07-26 JP JP2002513464A patent/JP5047442B2/ja not_active Expired - Fee Related
- 2001-07-26 AU AU2001280778A patent/AU2001280778B2/en not_active Ceased
- 2001-07-26 PT PT01959195T patent/PT1311270E/pt unknown
- 2001-07-26 BR BR0112775-6A patent/BR0112775A/pt not_active Application Discontinuation
- 2001-07-26 ES ES01959195T patent/ES2300349T3/es not_active Expired - Lifetime
- 2001-07-26 CN CNB018151426A patent/CN1329032C/zh not_active Expired - Fee Related
- 2001-07-26 MX MXPA03000824A patent/MXPA03000824A/es active IP Right Grant
- 2001-07-26 IL IL15406001A patent/IL154060A0/xx unknown
- 2001-07-26 AU AU8077801A patent/AU8077801A/xx active Pending
- 2001-07-26 DE DE60132337T patent/DE60132337T2/de not_active Expired - Lifetime
- 2001-07-26 CN CNB2006100813267A patent/CN100522172C/zh not_active Expired - Fee Related
- 2001-07-26 AT AT01959195T patent/ATE383159T1/de not_active IP Right Cessation
- 2001-07-26 CA CA2416535A patent/CA2416535C/en not_active Expired - Fee Related
- 2001-07-26 WO PCT/US2001/023420 patent/WO2002007729A1/en active IP Right Grant
-
2003
- 2003-01-20 IL IL154060A patent/IL154060A/en not_active IP Right Cessation
-
2004
- 2004-11-03 IL IL16501704A patent/IL165017A0/xx unknown
-
2007
- 2007-06-05 HK HK07105924.3A patent/HK1100814A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL154060A (en) | 2013-05-30 |
| ATE383159T1 (de) | 2008-01-15 |
| CA2416535A1 (en) | 2002-01-31 |
| PT1311270E (pt) | 2008-04-15 |
| CN100522172C (zh) | 2009-08-05 |
| AU2001280778B2 (en) | 2004-09-02 |
| WO2002007729A9 (en) | 2002-08-08 |
| EP1311270A1 (en) | 2003-05-21 |
| EP1311270B1 (en) | 2008-01-09 |
| EP1311270A4 (en) | 2006-04-12 |
| CA2416535C (en) | 2010-11-16 |
| CN1872067A (zh) | 2006-12-06 |
| AU8077801A (en) | 2002-02-05 |
| CN1329032C (zh) | 2007-08-01 |
| HK1100814A1 (en) | 2007-09-28 |
| BR0112775A (pt) | 2003-12-30 |
| MXPA03000824A (es) | 2004-11-01 |
| IL154060A0 (en) | 2003-07-31 |
| ES2300349T3 (es) | 2008-06-16 |
| DE60132337D1 (de) | 2008-02-21 |
| IL165017A0 (en) | 2005-12-18 |
| DE60132337T2 (de) | 2009-02-12 |
| JP2004517808A (ja) | 2004-06-17 |
| WO2002007729A1 (en) | 2002-01-31 |
| CN1461219A (zh) | 2003-12-10 |
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