JP5046941B2 - エボラ及び他のウイルスに対する防御に最適化されたワクチン - Google Patents

エボラ及び他のウイルスに対する防御に最適化されたワクチン Download PDF

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JP5046941B2
JP5046941B2 JP2007533758A JP2007533758A JP5046941B2 JP 5046941 B2 JP5046941 B2 JP 5046941B2 JP 2007533758 A JP2007533758 A JP 2007533758A JP 2007533758 A JP2007533758 A JP 2007533758A JP 5046941 B2 JP5046941 B2 JP 5046941B2
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seq
nucleic acid
filovirus
acid molecule
sequence
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JP2008514203A5 (enExample
JP2008514203A (ja
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サリバン，ナンシー
チャクラバーティ，ビマル
ヤン，ジ−ヨン
グラシア ポウ，マリア
ゴウズミット，ジャアプ
ジェイ． ネイベル，ガリー
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    • C12N2710/10011—Adenoviridae
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    • C12N2740/10011—Retroviridae
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    • C12N2760/00011—Details
    • C12N2760/14011—Filoviridae
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    • C12N2760/00011—Details
    • C12N2760/14011—Filoviridae
    • C12N2760/14111—Ebolavirus, e.g. Zaire ebolavirus
    • C12N2760/14134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor

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  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
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  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2007533758A 2004-09-27 2005-09-27 エボラ及び他のウイルスに対する防御に最適化されたワクチン Expired - Lifetime JP5046941B2 (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US61388304P 2004-09-27 2004-09-27
US60/613,883 2004-09-27
US67760605P 2005-05-03 2005-05-03
US60/677,606 2005-05-03
US67976705P 2005-05-10 2005-05-10
US60/679,767 2005-05-10
US70169405P 2005-07-22 2005-07-22
US60/701,694 2005-07-22
US71587405P 2005-09-09 2005-09-09
US60/715,874 2005-09-09
PCT/US2005/034798 WO2006037038A1 (en) 2004-09-27 2005-09-27 Optimized vaccines to provide protection against ebola and other viruses

Publications (3)

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JP2008514203A JP2008514203A (ja) 2008-05-08
JP2008514203A5 JP2008514203A5 (enExample) 2008-11-13
JP5046941B2 true JP5046941B2 (ja) 2012-10-10

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JP2007533758A Expired - Lifetime JP5046941B2 (ja) 2004-09-27 2005-09-27 エボラ及び他のウイルスに対する防御に最適化されたワクチン

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US (2) US8101739B2 (enExample)
EP (1) EP1797113B1 (enExample)
JP (1) JP5046941B2 (enExample)
AU (1) AU2005289439B2 (enExample)
CA (1) CA2581840C (enExample)
IL (1) IL182225A (enExample)
WO (1) WO2006037038A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005023170A1 (de) 2005-05-19 2006-11-23 Curevac Gmbh Optimierte Formulierung für mRNA
US7947286B2 (en) 2005-10-07 2011-05-24 Panthera Biopharma Llc Drosophila cell lines producing recombinant secretable filovirus surface glycoproteins lacking the membrane spanning domain
JP5670330B2 (ja) * 2008-08-07 2015-02-18 ハー マジェスティ ザ クイーン イン ライト オブ カナダ アズ リプリゼンテド バイ ザ ミニスター オブ ヘルスＨＥＲ ＭＡＪＥＳＴＹ ＴＨＥ ＱＵＥＥＮ ＩＮ ＲＩＧＨＴＯＦ ＣＡＮＡＤＡ ａｓ ｒｅｐｒｅｓｅｎｔｅｄ ｂｙ ＴＨＥ ＭＩＮＩＳＴＥＲ ＯＦ ＨＥＡＬＴＨ 最適化したプロモーター配列
EP3466440A1 (en) 2010-04-16 2019-04-10 The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services Chimpanzee adenoviral vector-based filovirus vaccines
ES2676196T3 (es) * 2010-12-14 2018-07-17 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Vacunas contra filovirus de adenovirus de serotipo 25 y serotipo 35
DK2764565T3 (da) 2011-10-05 2023-04-17 Oned Mat Inc Aktive siliciumnanostrukturmaterialer til lithiumionbatterier og fremgangsmåder, sammensætninger, komponenter og anordninger i forbindelser dermed
JP6389163B2 (ja) 2012-04-12 2018-09-12 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア フィロウイルスコンセンサス抗原、核酸構築物、およびそれから作製されるワクチン、ならびにその使用方法
CA2901501C (en) * 2013-02-21 2023-03-07 Children's Hospital Of Eastern Ontario Research Institute Inc. Vaccine composition
ZA201608812B (en) 2014-06-26 2019-08-28 Janssen Vaccines & Prevention Bv Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau
SG11201610446XA (en) 2014-06-26 2017-01-27 Janssen Vaccines & Prevention Bv Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau
NZ730511A (en) 2014-09-03 2022-04-29 Janssen Vaccines & Prevention Bv Methods and compositions for inducing protective immunity against filovirus infection
KR20190062617A (ko) 2014-09-03 2019-06-05 버베리안 노딕 에이/에스 면역 반응을 증대시키기 위한 방법 및 조성물
SG11201701506PA (en) * 2014-09-03 2017-03-30 Bavarian Nordic As Recombinant modified vaccinia virus ankara (mva) filovirus vaccine
US20170326225A1 (en) * 2014-12-16 2017-11-16 Curevac Ag Ebolavirus and marburgvirus vaccines
GB201502209D0 (en) 2015-02-10 2015-03-25 Sec Dep For Health The And Chancellor Masters And Scholars Of The University Of Oxford The And Micro Filovirus therapy
CA2977499C (en) * 2015-02-25 2023-10-03 Vanderbilt University Antibody-mediated neutralization of marburg virus
US11135280B2 (en) * 2016-03-28 2021-10-05 Integrated Biotherapeutics, Inc. Modified ebolavirus glycoproteins comprising mutations in the head and base domains that increase antibody cross-reactivity
WO2018011768A1 (en) 2016-07-15 2018-01-18 Janssen Vaccines And Prevention B.V. Methods and compositions for inducing protective immunity against a marburg virus infection
EP3484505A1 (en) 2016-07-15 2019-05-22 Janssen Vaccines & Prevention B.V. Methods and compositions for inducing protective immunity against a marburg virus infection
EP3606553A1 (en) 2017-04-06 2020-02-12 Janssen Vaccines & Prevention B.V. Mva-bn and ad26.zebov or ad26.filo prime-boost regimen
CA3107083A1 (en) * 2018-08-13 2020-02-20 Janssen Vaccines & Prevention B.V. Stabilized filovirus glycoprotein trimers
WO2022226060A1 (en) * 2021-04-21 2022-10-27 Vanderbilt University Antibody cocktail for treatment of ebolavirus infections

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4631211A (en) 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
WO1999032147A1 (en) * 1997-12-23 1999-07-01 The Regents Of The University Of Michigan Immunization for ebola virus infection
JP2005508916A (ja) * 2001-10-01 2005-04-07 アメリカ合衆国 霊長類におけるフィロウイルス感染に対する予防ワクチンの開発
WO2003092582A2 (en) * 2002-04-30 2003-11-13 The Trustees Of The University Of Pennsylvania Chimeric ebola virus envelopes and uses therefor

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Publication number Publication date
US20120156239A1 (en) 2012-06-21
EP1797113B1 (en) 2014-11-26
AU2005289439B2 (en) 2011-12-01
IL182225A0 (en) 2007-09-20
IL182225A (en) 2015-07-30
US9012618B2 (en) 2015-04-21
WO2006037038A9 (en) 2006-05-26
WO2006037038A1 (en) 2006-04-06
AU2005289439A1 (en) 2006-04-06
US8101739B2 (en) 2012-01-24
CA2581840A1 (en) 2006-04-06
JP2008514203A (ja) 2008-05-08
WO2006037038B1 (en) 2006-08-03
EP1797113A1 (en) 2007-06-20
CA2581840C (en) 2014-08-05
US20090232841A1 (en) 2009-09-17

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