JP5015783B2 - 流体検査システム - Google Patents
流体検査システム Download PDFInfo
- Publication number
- JP5015783B2 JP5015783B2 JP2007535292A JP2007535292A JP5015783B2 JP 5015783 B2 JP5015783 B2 JP 5015783B2 JP 2007535292 A JP2007535292 A JP 2007535292A JP 2007535292 A JP2007535292 A JP 2007535292A JP 5015783 B2 JP5015783 B2 JP 5015783B2
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- Prior art keywords
- active element
- fluid
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- inspection system
- fluid container
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- Expired - Fee Related
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
- F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
- F16K99/0019—Valves using a microdroplet or microbubble as the valve member
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
- F16K99/0034—Operating means specially adapted for microvalves
- F16K99/0036—Operating means specially adapted for microvalves operated by temperature variations
- F16K99/004—Operating means specially adapted for microvalves operated by temperature variations using radiation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/05—Flow-through cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0803—Disc shape
- B01L2300/0806—Standardised forms, e.g. compact disc [CD] format
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0442—Moving fluids with specific forces or mechanical means specific forces thermal energy, e.g. vaporisation, bubble jet
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
- B01L2400/0661—Valves, specific forms thereof with moving parts shape memory polymer valves
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K2099/0082—Microvalves adapted for a particular use
- F16K2099/0084—Chemistry or biology, e.g. "lab-on-a-chip" technology
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
- F16K99/0034—Operating means specially adapted for microvalves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0325—Cells for testing reactions, e.g. containing reagents
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/036—Cuvette constructions transformable, modifiable
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/0318—Processes
- Y10T137/0391—Affecting flow by the addition of material or energy
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Mechanical Engineering (AREA)
- Hematology (AREA)
- Pathology (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Optical Measuring Cells (AREA)
Description
上述の型の流体容器;
光ビームで前記流体容器の活性素子を選択的に照射する光学系;
を有する。上述の型の流体容器とは、つまりマイクロチャネルを有する流体容器であって、前記マイクチャネル内には、光ビームが到達可能なように、少なくとも1つの活性素子が設けられていて、前記活性素子は光によって、それぞれ異なる状態である活性状態に転移できる、流体容器である。
Claims (6)
- 光照射によって、それぞれ異なる形状のうちの活性状態に転移でき、少なくとも1方向でそれぞれ異なる伸張、及び/又は前記少なくとも1つの活性素子の活性化状態でそれぞれ異なる体積を有し、かつ吸収した光を熱に変換する変換材料及びゲルを有する、少なくとも1つの活性素子;
光ビームが到達可能な一定の場所に、前記少なくとも1つの活性素子が固定された状態で設けられているマイクロチャネルを有する流体容器;及び
350nm乃至850nmの範囲の波長を有する光ビームによって前記の流体容器の少なくとも1つの活性素子を選択的に光照射する光学系;
を有する検査システムであって、
前記光学系が、集束レーザービームによって、前記流体容器内部の領域を走査する手段を有し、かつ
前記レーザービームは、前記少なくとも1つの活性素子に集光される、
検査システム。 - 前記少なくとも1つの活性素子が、該少なくとも1つの活性素子の活性化状態又は非活性化状態のいずれかで前記マイクロチャネルを阻止するように設けられていることを特徴とする、請求項1に記載の検査システム。
- 前記少なくとも1つの活性素子がマイクロチャネルの壁に沿って設けられ、
それにより前記少なくとも1つの活性素子は、該少なくとも1つの活性素子の活性化状態から非活性化状態への転移中又はその逆の転移中に、流体を前記マイクロチャネルの外部に送り出す、
ことを特徴とする、請求項1に記載の検査システム。 - 前記マイクロチャネルが、少なくとも部分的に透明材料によって被覆されていることを特徴とする、請求項1に記載の検査システム。
- 前記光学系が、前記少なくとも1つの活性素子への所望の効果に基づいて、位置、強度及び/又は光ビームの照射時間を制御する制御装置を有することを特徴とする、請求項1に記載の検査システム。
- 前記光学系が、前記流体の光学的処理を実行するように備えられていることを特徴とする、請求項1に記載の検査システム。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04104900 | 2004-10-06 | ||
EP04104900.8 | 2004-10-06 | ||
PCT/IB2005/053196 WO2006038159A1 (en) | 2004-10-06 | 2005-09-28 | Microfluidic testing system |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2008516223A JP2008516223A (ja) | 2008-05-15 |
JP5015783B2 true JP5015783B2 (ja) | 2012-08-29 |
Family
ID=35502465
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007535292A Expired - Fee Related JP5015783B2 (ja) | 2004-10-06 | 2005-09-28 | 流体検査システム |
Country Status (5)
Country | Link |
---|---|
US (1) | US20080041453A1 (ja) |
EP (1) | EP1800107A1 (ja) |
JP (1) | JP5015783B2 (ja) |
CN (1) | CN101036044A (ja) |
WO (1) | WO2006038159A1 (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1922384A1 (en) * | 2005-08-26 | 2008-05-21 | Koninklijke Philips Electronics N.V. | Substrate material for handling and analyzing samples |
US20070092409A1 (en) * | 2005-10-21 | 2007-04-26 | Beatty Christopher C | Reconfigurable valve using optically active material |
US8367397B2 (en) | 2007-02-15 | 2013-02-05 | Honeywell International Inc. | Active biochip for nucleic acid analysis |
DE102007060352A1 (de) | 2007-12-12 | 2009-06-18 | Richter, Andreas, Dr. | Ansteuerung für integrierte aktive Mikrosysteme auf Hydrogelbasis |
KR101532314B1 (ko) * | 2009-10-27 | 2015-06-29 | 삼성전자주식회사 | 미세 유체 소자의 품질 관리 방법 및 품질 관리 장치 |
JP2014006108A (ja) * | 2012-06-22 | 2014-01-16 | Azbil Corp | 光学式粒子検出装置及び粒子の検出方法 |
ES2887874B2 (es) * | 2020-06-23 | 2022-11-18 | Consejo Superior Investigacion | Valvula microfluidica, procedimiento de fabricacion y usos de la misma |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3328300B2 (ja) * | 1991-07-18 | 2002-09-24 | アイシン精機株式会社 | 流体制御装置 |
US5288214A (en) * | 1991-09-30 | 1994-02-22 | Toshio Fukuda | Micropump |
US5800421A (en) * | 1996-06-12 | 1998-09-01 | Lemelson; Jerome H. | Medical devices using electrosensitive gels |
EA002403B1 (ru) * | 1997-02-28 | 2002-04-25 | Бурштейн Текнолоджис, Инк. | Лаборатория на диске |
US6485462B1 (en) * | 1997-08-27 | 2002-11-26 | Science Incorporated | Fluid delivery device with heat activated energy source |
US6375901B1 (en) * | 1998-06-29 | 2002-04-23 | Agilent Technologies, Inc. | Chemico-mechanical microvalve and devices comprising the same |
EP1214630A2 (en) | 1999-07-23 | 2002-06-19 | The Board Of Trustees Of The University Of Illinois | Microfabricated devices and method of manufacturing the same |
JP2002066999A (ja) * | 2000-08-30 | 2002-03-05 | Kawamura Inst Of Chem Res | 微小バルブ機構及びその製造方法 |
JP3628611B2 (ja) * | 2000-11-29 | 2005-03-16 | 独立行政法人科学技術振興機構 | マイクロシステムにおける流れの制御方法 |
US20030156991A1 (en) * | 2001-10-23 | 2003-08-21 | William Marsh Rice University | Optomechanically-responsive materials for use as light-activated actuators and valves |
JP4083452B2 (ja) * | 2002-03-28 | 2008-04-30 | 旭化成株式会社 | バルブ機構 |
AU2003235970A1 (en) * | 2002-04-30 | 2003-11-17 | Arkray, Inc. | Analysis instrument, sample analysis method and analysis device using the instrument, and method of forming opening in the instrument |
JP2004249381A (ja) * | 2003-02-18 | 2004-09-09 | Univ Waseda | マトリックス型可変マイクロ流路及びそのシステム |
GB0304082D0 (en) * | 2003-02-22 | 2003-03-26 | Synthese O Grande Vitesse Ltd | Improvements in and relating to circuits |
-
2005
- 2005-09-28 EP EP05795934A patent/EP1800107A1/en not_active Withdrawn
- 2005-09-28 JP JP2007535292A patent/JP5015783B2/ja not_active Expired - Fee Related
- 2005-09-28 CN CNA2005800338680A patent/CN101036044A/zh active Pending
- 2005-09-28 WO PCT/IB2005/053196 patent/WO2006038159A1/en active Application Filing
- 2005-09-28 US US11/576,531 patent/US20080041453A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2008516223A (ja) | 2008-05-15 |
CN101036044A (zh) | 2007-09-12 |
EP1800107A1 (en) | 2007-06-27 |
WO2006038159A1 (en) | 2006-04-13 |
US20080041453A1 (en) | 2008-02-21 |
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