JP5010914B2 - 磁性粒子の空間分布を決める方法及び磁性粒子を投与する組成物 - Google Patents

磁性粒子の空間分布を決める方法及び磁性粒子を投与する組成物 Download PDF

Info

Publication number
JP5010914B2
JP5010914B2 JP2006506849A JP2006506849A JP5010914B2 JP 5010914 B2 JP5010914 B2 JP 5010914B2 JP 2006506849 A JP2006506849 A JP 2006506849A JP 2006506849 A JP2006506849 A JP 2006506849A JP 5010914 B2 JP5010914 B2 JP 5010914B2
Authority
JP
Japan
Prior art keywords
magnetic
particles
magnetic field
magnetic particles
area
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2006506849A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006523492A5 (https=
JP2006523492A (ja
Inventor
ベルンハルド グライヒ
ユールゲン ワイゼネッカー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Philips NV
Original Assignee
Koninklijke Philips NV
Koninklijke Philips Electronics NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips NV, Koninklijke Philips Electronics NV filed Critical Koninklijke Philips NV
Publication of JP2006523492A publication Critical patent/JP2006523492A/ja
Publication of JP2006523492A5 publication Critical patent/JP2006523492A5/ja
Application granted granted Critical
Publication of JP5010914B2 publication Critical patent/JP5010914B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/416—Evaluating particular organs or parts of the immune or lymphatic systems the spleen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/0515—Magnetic particle imaging

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Nanotechnology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
JP2006506849A 2003-04-15 2004-04-15 磁性粒子の空間分布を決める方法及び磁性粒子を投与する組成物 Expired - Fee Related JP5010914B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03101017 2003-04-15
EP03101017.6 2003-04-15
PCT/IB2004/050444 WO2004091394A2 (en) 2003-04-15 2004-04-15 Method to determine the spatial distribution of magnetic particles and magnetic particle administering compositions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010247345A Division JP2011046735A (ja) 2003-04-15 2010-11-04 磁性粒子の空間分布を決める方法及び磁性粒子を投与する組成物

Publications (3)

Publication Number Publication Date
JP2006523492A JP2006523492A (ja) 2006-10-19
JP2006523492A5 JP2006523492A5 (https=) 2007-06-14
JP5010914B2 true JP5010914B2 (ja) 2012-08-29

Family

ID=33185923

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2006506849A Expired - Fee Related JP5010914B2 (ja) 2003-04-15 2004-04-15 磁性粒子の空間分布を決める方法及び磁性粒子を投与する組成物
JP2010247345A Pending JP2011046735A (ja) 2003-04-15 2010-11-04 磁性粒子の空間分布を決める方法及び磁性粒子を投与する組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010247345A Pending JP2011046735A (ja) 2003-04-15 2010-11-04 磁性粒子の空間分布を決める方法及び磁性粒子を投与する組成物

Country Status (4)

Country Link
US (1) US20060248944A1 (https=)
EP (1) EP1615559B1 (https=)
JP (2) JP5010914B2 (https=)
WO (1) WO2004091394A2 (https=)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006051732A1 (ja) * 2004-11-10 2006-05-18 Konica Minolta Medical & Graphic, Inc. 被覆磁性粒子含有製剤およびその製造方法、並びに診断治療システム
CN101087558B (zh) * 2004-12-22 2010-10-06 皇家飞利浦电子股份有限公司 用于通过磁选法确定位置的标示器
CN101563033B (zh) * 2006-12-20 2013-05-29 皇家飞利浦电子股份有限公司 用于影响和/或检测作用区域中的磁性粒子的装置和方法
US8269501B2 (en) * 2008-01-08 2012-09-18 William Marsh Rice University Methods for magnetic imaging of geological structures
WO2009104151A2 (en) * 2008-02-22 2009-08-27 Koninklijke Philips Electronics N.V. Arrangement and method for influencing and/or detecting magnetic particles in a region of action of an examination object and use of an arrangement
US8884617B2 (en) 2008-06-23 2014-11-11 The Regents Of The University Of California Magnetic particle imaging devices and methods
WO2010008478A2 (en) * 2008-06-23 2010-01-21 The Regents Of The University Of California, Berkeley Improved techniques for magnetic particle imaging
US8981770B2 (en) 2009-07-20 2015-03-17 Koninklijke Philips N.V. Apparatus and method for influencing and/or detecting magnetic particles
CN102469952B (zh) 2009-08-07 2014-11-12 皇家飞利浦电子股份有限公司 用于确定至少一个电磁量的设备和方法
CN102481111B (zh) 2009-08-21 2014-12-17 皇家飞利浦电子股份有限公司 用于生成和移动具有无场线的磁场的设备和方法
WO2011024137A1 (en) 2009-08-31 2011-03-03 Koninklijke Philips Electronics N.V. Multi-level inverter apparatus and inversion method
EP2475297B1 (en) 2009-09-11 2020-05-13 Koninklijke Philips N.V. Apparatus, method, and copmuter program for influencing and/or detecting magnetic particles in a field of view
WO2011030275A1 (en) 2009-09-11 2011-03-17 Koninklijke Philips Electronics N.V. Apparatus and method for influencing and/or detecting magnetic particles
CN102497811B (zh) 2009-09-14 2015-01-28 皇家飞利浦电子股份有限公司 用于控制导管移动以及用于导管定位的设备和方法
CN102655805B (zh) 2009-09-14 2014-09-17 皇家飞利浦电子股份有限公司 用于使用mpi进行无创心脏内心电描记的设备和方法
EP2477539B1 (en) 2009-09-14 2017-01-11 Koninklijke Philips N.V. Apparatus and method for measuring the internal pressure of an examination object
RU2012138332A (ru) 2010-02-08 2014-03-20 Конинклейке Филипс Электроникс Н.В. Устройство и способ регистрации магнитных частиц
RU2556967C2 (ru) 2010-02-08 2015-07-20 Конинклейке Филипс Электроникс Н.В. Устройство и способ воздействия на магнитные частицы и/или их обнаружения в поле зрения с использованием матрицы наборов односторонних передающихся катушек
WO2011121511A1 (en) 2010-04-01 2011-10-06 Koninklijke Philips Electronics N.V. Apparatus and method for forming a concentration image of the concentration of magnetic particles arranged in a field of view field of the invention
WO2011121487A1 (en) 2010-04-01 2011-10-06 Koninklijke Philips Electronics N.V. Apparatus and method for forming a concentration image of the concentration of magnetic particles arranged in a field of view
DE102010013900B4 (de) 2010-04-01 2013-01-03 Hochschule Für Angewandte Wissenschaften Fachhochschule Würzburg-Schweinfurt Verfahren zur Bildgebung mittels magnetischer Kleinstpartikel sowie Vorrichtung hierfür
WO2012007871A1 (en) 2010-07-13 2012-01-19 Koninklijke Philips Electronics N.V. System and method for generating a system function for use in the reconstruction of images
WO2012046157A1 (en) 2010-10-05 2012-04-12 Koninklijke Philips Electronics N.V. Apparatus and method for locating magnetic particles
EP2648611B1 (en) * 2010-12-10 2015-02-25 Koninklijke Philips N.V. Apparatus and method for influencing and/or detecting magnetic particles
EP2648610B1 (en) 2010-12-10 2014-07-02 Koninklijke Philips N.V. Apparatus and method for influencing and/or detecting magnetic particles
JP6246129B2 (ja) 2011-11-16 2017-12-13 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 広視野を有する、磁性粒子に影響を及ぼし、且つ／又は磁性粒子を検出する装置及び方法
JP6106184B2 (ja) 2011-12-02 2017-03-29 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． Ｍｐｉのためのコイル配置
EP2790574B1 (en) 2011-12-15 2018-03-21 Koninklijke Philips N.V. Removal of background in mpi
WO2013114247A2 (en) 2012-02-01 2013-08-08 Koninklijke Philips N.V. Multimodal fiducial marker and marker arrangement
US9498149B2 (en) 2012-10-12 2016-11-22 Koninklijke Philips N.V. Dynamic background correction in MPI
CN104768458A (zh) 2012-11-07 2015-07-08 皇家飞利浦有限公司 在mpi装置中使用的磁性设备
US10222304B2 (en) 2013-03-15 2019-03-05 Massachusetts Institute Of Technology Deposition and imaging of particles on planar substrates
WO2014147589A1 (en) 2013-03-21 2014-09-25 Koninklijke Philips N.V. Apparatus and method for influencing and/or detecting magnetic particles comprising compensation unit
EP2994769A4 (en) * 2013-03-21 2017-03-01 Weinberg Medical Physics LLC Method and apparatus for high resolution physiological imaging of neurons
EP3043703A1 (en) 2013-09-11 2016-07-20 Koninklijke Philips N.V. Mpi apparatus with fast field of view motion.
US10542918B2 (en) 2013-10-23 2020-01-28 Verily Life Sciences Llc Modulation of a response signal to distinguish between analyte and background signals
JP6387409B2 (ja) * 2013-10-23 2018-09-05 ヴェリリー ライフ サイエンシズ エルエルシー 外部磁界による血管系内の磁性粒子の空間変調
JP5815902B1 (ja) 2014-05-14 2015-11-17 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． ブリッジユニットを有し、磁性粒子に影響を与える及び／又は検出する装置及び方法
WO2017032903A1 (en) 2015-08-27 2017-03-02 Koninklijke Philips N.V. Magnet arrangement and magnetic particle imaging device
WO2017076627A1 (en) * 2015-11-03 2017-05-11 Koninklijke Philips N.V. Examination apparatus for tracking permanently magnetic beads
US10775452B2 (en) 2016-07-12 2020-09-15 Magnetic Insight, Inc. Magnetic particle imaging
US11529193B2 (en) * 2017-08-10 2022-12-20 Northern Digital Inc. Tracking a sensor that includes a ferrofluid
US10901051B2 (en) 2017-08-15 2021-01-26 Uchicago Argonne, Llc Ferromagnetic particles as ultra-sensitive non-linear response labels for magnetic particles imaging (MPI) and sensing applications
WO2020186185A1 (en) 2019-03-13 2020-09-17 Magnetic Insight, Inc. Magnetic particle actuation
JP7450812B2 (ja) 2021-05-18 2024-03-15 三菱電機株式会社 生体情報検出装置および生体情報検出装置の作動方法

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3592185A (en) * 1967-04-18 1971-07-13 Yeda Res & Dev Ferromagnetic contrast media and method of use
SE463651B (sv) * 1983-12-21 1991-01-07 Nycomed As Diagnostikum och kontrastmedel
PT81498B (pt) 1984-11-23 1987-12-30 Schering Ag Processo para a preparacao de composicoes para diagnostico contendo particulas magneticas
US4827945A (en) * 1986-07-03 1989-05-09 Advanced Magnetics, Incorporated Biologically degradable superparamagnetic materials for use in clinical applications
GB9007408D0 (en) * 1990-04-02 1990-05-30 Nycomed As Compositions
US5370901A (en) * 1991-02-15 1994-12-06 Bracco International B.V. Compositions for increasing the image contrast in diagnostic investigations of the digestive tract of patients
US5406950A (en) * 1993-12-23 1995-04-18 Mallinckrodt Medical, Inc. Inhalable contrast agent
US6470220B1 (en) * 1999-03-29 2002-10-22 The Regents Of The University Of California Diagnosis and treatment of cancers using in vivo magnetic domains
US7731648B2 (en) * 2001-07-25 2010-06-08 Aduro Biotech Magnetic nanoscale particle compositions, and therapeutic methods related thereto
DE10151779A1 (de) * 2001-10-19 2003-05-08 Philips Corp Intellectual Pty Verfahren zum Lokalisieren eines Gegenstandes in einer MR-Apparatur sowie Katheter und MR-Apparatur zur Durchführung des Verfahrens
DE10151778A1 (de) * 2001-10-19 2003-05-08 Philips Corp Intellectual Pty Verfahren zur Ermittlung der räumlichen Verteilung magnetischer Partikel
GB0130284D0 (en) * 2001-12-19 2002-02-06 Glaxo Group Ltd Medicament dispenser
DE10202986A1 (de) * 2002-01-26 2003-07-31 Philips Intellectual Property Spulensystem für eine MR-Apparatur sowie MR-Apparatur mit einem solchen Spulensystem
DE10238853A1 (de) * 2002-08-24 2004-03-04 Philips Intellectual Property & Standards Gmbh Verfahren zur lokalen Erwärmung mit magnetischen Partikeln
DE10240960A1 (de) * 2002-09-05 2004-03-18 Philips Intellectual Property & Standards Gmbh Katheter, insbesondere zur Verwendung bei der MR-Bildgebung
DE10249239A1 (de) * 2002-10-23 2004-05-06 Philips Intellectual Property & Standards Gmbh Magnetresonanz-Bildgerät mit elektrischer Zusatzeinrichtung
CN100548214C (zh) * 2003-04-15 2009-10-14 皇家飞利浦电子股份有限公司 影响磁性颗粒的设备
US7370656B2 (en) * 2003-04-15 2008-05-13 Koninklijke Philips Electronics N.V. Method and arrangement for influencing magnetic particles and detecting interfering material
CN1774200B (zh) * 2003-04-15 2010-07-28 皇家飞利浦电子股份有限公司 对检测区域内的状态变量进行空间解像测定的装置及方法
WO2004091390A2 (en) * 2003-04-15 2004-10-28 Philips Intellectual Property & Standards Gmbh Device and method for examination and use of an electrical field in an object under examination containing magnetic particles
WO2004091395A2 (en) * 2003-04-15 2004-10-28 Philips Intellectual Property & Standards Gmbh Method for spatially resolved determination of magnetic particle distribution in an area of examination
US7758622B2 (en) * 2003-04-15 2010-07-20 Koninklijke Philips Electronics N.V. Method and apparatus for influencing magnetic particles
EP1615557B1 (en) * 2003-04-15 2012-09-19 Philips Intellectual Property & Standards GmbH Method and apparatus for improved determination of spatial non-agglomerated magnetic particle distribution in an area of examination
US9603544B2 (en) * 2003-04-15 2017-03-28 Koninklijke Philips N.V. Method of determining state variables and changes in state variables
US9107581B2 (en) * 2003-04-15 2015-08-18 Koninklijke Philips N.V. Elastography device and method for determining and imaging of mechanical and elastic parameters of an examination object
ATE546091T1 (de) * 2003-04-15 2012-03-15 Koninkl Philips Electronics Nv Verfahren zur räumlich aufgelösten bestimmung physikalischer, chemischer und biologischer eigenschaften oder zustandsgrössen
DE602004017764D1 (de) * 2003-09-30 2008-12-24 Koninkl Philips Electronics Nv Elektroakustisches kabel für magnetresonanzanwendungen
JP4804363B2 (ja) * 2004-02-09 2011-11-02 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 蛍光顕微鏡装置
CN1926443B (zh) * 2004-03-03 2010-09-01 皇家飞利浦电子股份有限公司 具有增强器铁的磁共振成像扫描仪
CN1947028B (zh) * 2004-04-23 2011-01-26 皇家飞利浦电子股份有限公司 配备有电气附件装置的磁共振成像系统
JP5247145B2 (ja) * 2004-06-28 2013-07-24 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ Ｒｆ場で使用する送信線
WO2006027738A1 (en) * 2004-09-10 2006-03-16 Philips Intellectual Property & Standards Gmbh Compounds and methods for combined optical-ultrasound imaging
CN100522055C (zh) * 2004-09-28 2009-08-05 皇家飞利浦电子股份有限公司 判定磁性粒子空间分布的方法

Also Published As

Publication number Publication date
WO2004091394A3 (en) 2005-03-17
EP1615559A2 (en) 2006-01-18
JP2006523492A (ja) 2006-10-19
US20060248944A1 (en) 2006-11-09
WO2004091394A2 (en) 2004-10-28
EP1615559B1 (en) 2012-08-22
JP2011046735A (ja) 2011-03-10

Similar Documents

Publication Publication Date Title
JP5010914B2 (ja) 磁性粒子の空間分布を決める方法及び磁性粒子を投与する組成物
US9603544B2 (en) Method of determining state variables and changes in state variables
US9808173B2 (en) Method for the spatially resolved determination of physcial, chemical and/or biological properties or state variables
JP4583370B2 (ja) 検査領域内の磁性粒子の分布を空間分解して特定する方法
Dutz et al. Magnetic multicore nanoparticles for hyperthermia—influence of particle immobilization in tumour tissue on magnetic properties
Bakenecker et al. Magnetic particle imaging in vascular medicine
US20060248945A1 (en) Method and apparatus for improved determination of spatial non-agglomerated magnetic particle distribution in an area of examination
Gleich Principles and applications of magnetic particle imaging
WO2012046157A1 (en) Apparatus and method for locating magnetic particles
BRPI0806911A2 (pt) Método para influenciar e/ou detectar partículas magnéticas em uma região de ação, partículas magnéticas, e, uso das mesmas
Baffa et al. Development of an optical pumped gradiometric system to detect magnetic relaxation of magnetic nanoparticles
Kumar Magnetic Particle Imaging in Oncology: Advances and Prospects for Tumor Progression Monitoring and Targeted Therapy
Olamaei et al. Three‐dimensional reconstruction of a vascular network by dynamic tracking of magnetite nanoparticles
Mohseni Scalable strategies for tumour targeting of magnetic carriers and seeds
Toifl Transition to superparamagnetic behaviour of magnetite nanoparticles used for hyperthermia applications
Cornnell Optimization of contrast agents for high magnetic fields
ヌルミザ,ビンティ,オスマン Magnetic Nanoparticle Imaging for Biomedical Applications
Pasmans et al. Magnetic nanoparticles for magnetic particle imaging: from particle characterization to image simulations
Park et al. open access to scientific and medical research
白石 Development of Magnetic Nanoparticle Imaging Using Gradient Magnetic Field and Electric Scanning of Field Free Point
Wang APPLICATIONS OF NANOTECHNOLOGY IN NEUROSCIENCE: Functionalized superparamagnetic nanoparticles as contrast enhancers in experimental magnetic resonance imaging
SARITAS CURRENT STUDIES IN ELECTRICAL ELECTRONICS AND COMPUTER ENGINEERING

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070413

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070413

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100511

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100805

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100812

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20101104

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110104

RD03 Notification of appointment of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7423

Effective date: 20110331

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110404

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110411

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110428

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20111213

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120217

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20120315

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20120508

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20120604

R150 Certificate of patent or registration of utility model

Ref document number: 5010914

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20150608

Year of fee payment: 3

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees