JP5010914B2 - 磁性粒子の空間分布を決める方法及び磁性粒子を投与する組成物 - Google Patents
磁性粒子の空間分布を決める方法及び磁性粒子を投与する組成物 Download PDFInfo
- Publication number
- JP5010914B2 JP5010914B2 JP2006506849A JP2006506849A JP5010914B2 JP 5010914 B2 JP5010914 B2 JP 5010914B2 JP 2006506849 A JP2006506849 A JP 2006506849A JP 2006506849 A JP2006506849 A JP 2006506849A JP 5010914 B2 JP5010914 B2 JP 5010914B2
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- JP
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- Prior art keywords
- magnetic
- particles
- magnetic field
- magnetic particles
- area
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
- A61B5/416—Evaluating particular organs or parts of the immune or lymphatic systems the spleen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/0515—Magnetic particle imaging
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Surgery (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Nanotechnology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03101017 | 2003-04-15 | ||
| EP03101017.6 | 2003-05-15 | ||
| PCT/IB2004/050444 WO2004091394A2 (en) | 2003-04-15 | 2004-04-15 | Method to determine the spatial distribution of magnetic particles and magnetic particle administering compositions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010247345A Division JP2011046735A (ja) | 2003-04-15 | 2010-11-04 | 磁性粒子の空間分布を決める方法及び磁性粒子を投与する組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006523492A JP2006523492A (ja) | 2006-10-19 |
| JP2006523492A5 JP2006523492A5 (https=) | 2007-06-14 |
| JP5010914B2 true JP5010914B2 (ja) | 2012-08-29 |
Family
ID=33185923
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006506849A Expired - Fee Related JP5010914B2 (ja) | 2003-04-15 | 2004-04-15 | 磁性粒子の空間分布を決める方法及び磁性粒子を投与する組成物 |
| JP2010247345A Pending JP2011046735A (ja) | 2003-04-15 | 2010-11-04 | 磁性粒子の空間分布を決める方法及び磁性粒子を投与する組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010247345A Pending JP2011046735A (ja) | 2003-04-15 | 2010-11-04 | 磁性粒子の空間分布を決める方法及び磁性粒子を投与する組成物 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20060248944A1 (https=) |
| EP (1) | EP1615559B1 (https=) |
| JP (2) | JP5010914B2 (https=) |
| WO (1) | WO2004091394A2 (https=) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006051732A1 (ja) * | 2004-11-10 | 2006-05-18 | Konica Minolta Medical & Graphic, Inc. | 被覆磁性粒子含有製剤およびその製造方法、並びに診断治療システム |
| CN101087558B (zh) * | 2004-12-22 | 2010-10-06 | 皇家飞利浦电子股份有限公司 | 用于通过磁选法确定位置的标示器 |
| US8183861B2 (en) | 2006-12-20 | 2012-05-22 | Koninklijke Philips Electronics N.V. | Arrangement including compensation for influencing and/or detecting magnetic particles in a region of action |
| US8269501B2 (en) * | 2008-01-08 | 2012-09-18 | William Marsh Rice University | Methods for magnetic imaging of geological structures |
| WO2009104151A2 (en) * | 2008-02-22 | 2009-08-27 | Koninklijke Philips Electronics N.V. | Arrangement and method for influencing and/or detecting magnetic particles in a region of action of an examination object and use of an arrangement |
| EP4270143A3 (en) | 2008-06-23 | 2023-12-27 | The Regents Of The University Of California, Berkeley | Improved techniques for magnetic particle imaging |
| US8884617B2 (en) | 2008-06-23 | 2014-11-11 | The Regents Of The University Of California | Magnetic particle imaging devices and methods |
| US8981770B2 (en) | 2009-07-20 | 2015-03-17 | Koninklijke Philips N.V. | Apparatus and method for influencing and/or detecting magnetic particles |
| US8812078B2 (en) | 2009-08-07 | 2014-08-19 | Koninklijke Philips N.V. | Apparatus and method for determining at least one electromagnetic quantity |
| CN102481111B (zh) | 2009-08-21 | 2014-12-17 | 皇家飞利浦电子股份有限公司 | 用于生成和移动具有无场线的磁场的设备和方法 |
| WO2011024137A1 (en) | 2009-08-31 | 2011-03-03 | Koninklijke Philips Electronics N.V. | Multi-level inverter apparatus and inversion method |
| US9192320B2 (en) | 2009-09-11 | 2015-11-24 | Koninklijke Philips N.V. | Apparatus and method for influencing and/or detecting magnetic particles in a field of view |
| WO2011030275A1 (en) | 2009-09-11 | 2011-03-17 | Koninklijke Philips Electronics N.V. | Apparatus and method for influencing and/or detecting magnetic particles |
| US8903482B2 (en) | 2009-09-14 | 2014-12-02 | Koninklijke Philips N.V. | Apparatus and method for non-invasive intracardiac electrocardiography using MPI |
| CN102497807B (zh) | 2009-09-14 | 2015-06-17 | 皇家飞利浦电子股份有限公司 | 用于测量检查对象的内压的设备 |
| CN102497811B (zh) | 2009-09-14 | 2015-01-28 | 皇家飞利浦电子股份有限公司 | 用于控制导管移动以及用于导管定位的设备和方法 |
| RU2012138332A (ru) | 2010-02-08 | 2014-03-20 | Конинклейке Филипс Электроникс Н.В. | Устройство и способ регистрации магнитных частиц |
| BR112012019482A2 (pt) | 2010-02-08 | 2018-07-24 | Koninl Philips Electronics Nv | aparelho para influenciar e\ou detectar partículas magnéticas em um campo de visão, metodo para influenciar e/ou detectar partículas magneticas em um campo de visão e programa de computador |
| WO2011121487A1 (en) | 2010-04-01 | 2011-10-06 | Koninklijke Philips Electronics N.V. | Apparatus and method for forming a concentration image of the concentration of magnetic particles arranged in a field of view |
| DE102010013900B4 (de) * | 2010-04-01 | 2013-01-03 | Hochschule Für Angewandte Wissenschaften Fachhochschule Würzburg-Schweinfurt | Verfahren zur Bildgebung mittels magnetischer Kleinstpartikel sowie Vorrichtung hierfür |
| WO2011121511A1 (en) | 2010-04-01 | 2011-10-06 | Koninklijke Philips Electronics N.V. | Apparatus and method for forming a concentration image of the concentration of magnetic particles arranged in a field of view field of the invention |
| WO2012007871A1 (en) | 2010-07-13 | 2012-01-19 | Koninklijke Philips Electronics N.V. | System and method for generating a system function for use in the reconstruction of images |
| WO2012046157A1 (en) | 2010-10-05 | 2012-04-12 | Koninklijke Philips Electronics N.V. | Apparatus and method for locating magnetic particles |
| EP2648610B1 (en) | 2010-12-10 | 2014-07-02 | Koninklijke Philips N.V. | Apparatus and method for influencing and/or detecting magnetic particles |
| RU2592015C2 (ru) * | 2010-12-10 | 2016-07-20 | Конинклейке Филипс Электроникс Н.В. | Устройство и способ для воздействия на и/или обнаружения магнитных частиц |
| RU2624315C2 (ru) | 2011-11-16 | 2017-07-03 | Конинклейке Филипс Н.В. | Устройство и способ оказания влияния и обнаружения магнитных частиц, имеющие большое поле зрения |
| WO2013080145A1 (en) | 2011-12-02 | 2013-06-06 | Koninklijke Philips Electronics N.V. | Coil arrangement for mpi |
| RU2622481C2 (ru) | 2011-12-15 | 2017-06-15 | Конинклейке Филипс Н.В. | Удаление фона при получении изображений с использованием магнитных частиц |
| CN104105456B (zh) | 2012-02-01 | 2017-07-11 | 皇家飞利浦有限公司 | 多模态基准标记和标记装置 |
| US9498149B2 (en) | 2012-10-12 | 2016-11-22 | Koninklijke Philips N.V. | Dynamic background correction in MPI |
| WO2014072854A1 (en) | 2012-11-07 | 2014-05-15 | Koninklijke Philips N.V. | Magnetic device for use in an mpi apparatus |
| WO2014143981A1 (en) | 2013-03-15 | 2014-09-18 | Massachusetts Institute Of Technology | Deposition and imaging of particles on planar substrates |
| WO2014147589A1 (en) | 2013-03-21 | 2014-09-25 | Koninklijke Philips N.V. | Apparatus and method for influencing and/or detecting magnetic particles comprising compensation unit |
| WO2014149064A1 (en) * | 2013-03-21 | 2014-09-25 | Weinberg Medical Physics Llc | Method and apparatus for high resolution physiological imaging of neurons |
| US10168408B2 (en) | 2013-09-11 | 2019-01-01 | Koninklijke Philips N.V. | MPI apparatus with fast field of view motion |
| CA2928154C (en) * | 2013-10-23 | 2019-01-08 | Verily Life Sciences Llc | Spatial modulation of magnetic particles in vasculature by external magnetic field |
| US10542918B2 (en) | 2013-10-23 | 2020-01-28 | Verily Life Sciences Llc | Modulation of a response signal to distinguish between analyte and background signals |
| JP5815902B1 (ja) | 2014-05-14 | 2015-11-17 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | ブリッジユニットを有し、磁性粒子に影響を与える及び/又は検出する装置及び方法 |
| WO2017032903A1 (en) | 2015-08-27 | 2017-03-02 | Koninklijke Philips N.V. | Magnet arrangement and magnetic particle imaging device |
| WO2017076627A1 (en) * | 2015-11-03 | 2017-05-11 | Koninklijke Philips N.V. | Examination apparatus for tracking permanently magnetic beads |
| CN109952060B (zh) | 2016-07-12 | 2023-07-18 | 马格内蒂克因赛特公司 | 磁性粒子成像 |
| US11529193B2 (en) * | 2017-08-10 | 2022-12-20 | Northern Digital Inc. | Tracking a sensor that includes a ferrofluid |
| US10901051B2 (en) | 2017-08-15 | 2021-01-26 | Uchicago Argonne, Llc | Ferromagnetic particles as ultra-sensitive non-linear response labels for magnetic particles imaging (MPI) and sensing applications |
| US11890488B2 (en) | 2019-03-13 | 2024-02-06 | Magnetic Insight, Inc. | Magnetic particle actuation |
| CN117320621A (zh) | 2021-05-18 | 2023-12-29 | 三菱电机株式会社 | 生物体信息检测装置以及生物体信息检测方法 |
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| US4827945A (en) | 1986-07-03 | 1989-05-09 | Advanced Magnetics, Incorporated | Biologically degradable superparamagnetic materials for use in clinical applications |
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| EP1615554B1 (en) * | 2003-04-15 | 2017-12-20 | Philips Intellectual Property & Standards GmbH | Method and arrangement for influencing magnetic particles and detecting interfering material |
| EP1615557B1 (en) * | 2003-04-15 | 2012-09-19 | Philips Intellectual Property & Standards GmbH | Method and apparatus for improved determination of spatial non-agglomerated magnetic particle distribution in an area of examination |
| JP4583369B2 (ja) * | 2003-04-15 | 2010-11-17 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 磁性粒子に影響を与える方法及び装置 |
| CN1774210B (zh) * | 2003-04-15 | 2010-05-12 | 皇家飞利浦电子股份有限公司 | 用于对检查对象的机械和弹性参数进行确定和成像的弹性检查设备和方法 |
| ATE543428T1 (de) * | 2003-04-15 | 2012-02-15 | Koninkl Philips Electronics Nv | Anordnung sowie verfahren zur räumlich aufgelösten bestimmung von zustandsgrössen in einem untersuchungsbereich |
| WO2004091393A1 (en) * | 2003-04-15 | 2004-10-28 | Philips Intellectual Property & Standards Gmbh | Arrangement for influencing magnetic particles |
| JP4583370B2 (ja) * | 2003-04-15 | 2010-11-17 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 検査領域内の磁性粒子の分布を空間分解して特定する方法 |
| WO2004091390A2 (en) * | 2003-04-15 | 2004-10-28 | Philips Intellectual Property & Standards Gmbh | Device and method for examination and use of an electrical field in an object under examination containing magnetic particles |
| US9603544B2 (en) * | 2003-04-15 | 2017-03-28 | Koninklijke Philips N.V. | Method of determining state variables and changes in state variables |
| ATE414336T1 (de) * | 2003-09-30 | 2008-11-15 | Koninkl Philips Electronics Nv | Elektroakustisches kabel für magnetresonanzanwendungen |
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| EP1743186B1 (en) * | 2004-04-23 | 2017-07-26 | Koninklijke Philips N.V. | Magnetic resonance imaging system provided with an electrical accessory device |
| US7750637B2 (en) * | 2004-06-28 | 2010-07-06 | Koninklijke Philips Electronics N.V. | Transmission line for use in RF fields |
| WO2006027738A1 (en) * | 2004-09-10 | 2006-03-16 | Philips Intellectual Property & Standards Gmbh | Compounds and methods for combined optical-ultrasound imaging |
| EP1816958B1 (en) * | 2004-09-28 | 2011-08-17 | Philips Intellectual Property & Standards GmbH | Method of determining a spatial distribution of magnetic particles |
-
2004
- 2004-04-15 JP JP2006506849A patent/JP5010914B2/ja not_active Expired - Fee Related
- 2004-04-15 US US10/552,819 patent/US20060248944A1/en not_active Abandoned
- 2004-04-15 EP EP04727653A patent/EP1615559B1/en not_active Expired - Lifetime
- 2004-04-15 WO PCT/IB2004/050444 patent/WO2004091394A2/en not_active Ceased
-
2010
- 2010-11-04 JP JP2010247345A patent/JP2011046735A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1615559B1 (en) | 2012-08-22 |
| EP1615559A2 (en) | 2006-01-18 |
| WO2004091394A3 (en) | 2005-03-17 |
| JP2011046735A (ja) | 2011-03-10 |
| JP2006523492A (ja) | 2006-10-19 |
| WO2004091394A2 (en) | 2004-10-28 |
| US20060248944A1 (en) | 2006-11-09 |
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