JP4896123B2 - 筋ジストロフィの処置のためのキノン誘導体２，３−ジメトキシ−５−メチル−６−（１０−ヒドロキシデシル）−１，４−ベンゾキノン - Google Patents
筋ジストロフィの処置のためのキノン誘導体２，３−ジメトキシ−５−メチル−６−（１０−ヒドロキシデシル）−１，４−ベンゾキノン Download PDFInfo
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- JP4896123B2 JP4896123B2 JP2008502302A JP2008502302A JP4896123B2 JP 4896123 B2 JP4896123 B2 JP 4896123B2 JP 2008502302 A JP2008502302 A JP 2008502302A JP 2008502302 A JP2008502302 A JP 2008502302A JP 4896123 B2 JP4896123 B2 JP 4896123B2
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P9/12—Antihypertensives
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- Chemical & Material Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Neurology (AREA)
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- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| EP05006137.3 | 2005-03-21 | ||
| EP05006137 | 2005-03-21 | ||
| PCT/EP2006/002536 WO2006100017A1 (en) | 2005-03-21 | 2006-03-20 | Quinone derivative 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1 ,4- benzoquinone for the treatment of muscular dystrophies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008533182A JP2008533182A (ja) | 2008-08-21 |
| JP4896123B2 true JP4896123B2 (ja) | 2012-03-14 |
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| EP (1) | EP1861080B1 (https=) |
| JP (1) | JP4896123B2 (https=) |
| AT (1) | ATE468849T1 (https=) |
| AU (1) | AU2006226623B2 (https=) |
| CA (1) | CA2602290C (https=) |
| CY (1) | CY1110182T1 (https=) |
| DE (1) | DE602006014514D1 (https=) |
| DK (1) | DK1861080T3 (https=) |
| ES (1) | ES2345353T3 (https=) |
| MX (1) | MX2007011571A (https=) |
| NZ (1) | NZ561235A (https=) |
| PL (1) | PL1861080T3 (https=) |
| PT (1) | PT1861080E (https=) |
| SI (1) | SI1861080T1 (https=) |
| WO (1) | WO2006100017A1 (https=) |
| ZA (1) | ZA200707833B (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103271935A (zh) | 2006-08-01 | 2013-09-04 | 普里克萨斯医药股份有限公司 | 泊洛沙姆用于预防和/或治疗心力衰竭的用途 |
| EP1891946A1 (en) * | 2006-08-14 | 2008-02-27 | Santhera Pharmaceuticals (Schweiz) AG | Transmucosal administration of 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone |
| WO2009079562A2 (en) | 2007-12-17 | 2009-06-25 | The Regents Of The University Of Michigan | Compositions and methods for treating and preventing skeletal muscle deficiencies |
| SI2108366T1 (sl) * | 2008-04-09 | 2012-01-31 | Santhera Pharmaceuticals Ch | Idebenon za zdravljenje respiratorne bolezni pri miĺ iäśni distrofiji |
| EP2246048A1 (en) | 2009-04-30 | 2010-11-03 | Santhera Pharmaceuticals (Schweiz) AG | Quinone derivative 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone for the treatment of primary progressive multiple sclerosis |
| DK2605769T3 (en) | 2010-08-16 | 2016-10-24 | Santhera Pharmaceuticals (Schweiz) Ag | Benzoquinonderivater for the treatment of mitochondrial diseases of the eye |
| CN103086861B (zh) * | 2012-11-12 | 2015-09-16 | 刘炜 | 羟癸基苯醌衍生物及其用途 |
| US20230047313A1 (en) * | 2019-12-16 | 2023-02-16 | Children`S Medical Center Corporation | Treating heart disease in muscular dystrophy patients |
| EP4351545A1 (en) | 2021-06-07 | 2024-04-17 | Katholieke Universiteit Leuven | Idebenone in the treatment of drug resistant epilepsy |
| CN113827585B (zh) * | 2021-10-27 | 2023-04-11 | 山东大学齐鲁医院 | 艾地苯在治疗肢带型肌营养不良2g型中的应用 |
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| AU8562998A (en) | 1997-08-12 | 1999-03-01 | Takeda Chemical Industries Ltd. | Idebenone-containing preparation for percutaneous administration |
| JPH11116470A (ja) | 1997-08-12 | 1999-04-27 | Takeda Chem Ind Ltd | イデベノン含有経皮投与製剤 |
| US20030013772A1 (en) * | 2000-02-23 | 2003-01-16 | Murphy Michael A. | Composition, synthesis and therapeutic applications of polyamines |
| CA2272971C (en) | 1998-10-29 | 2008-01-15 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Quinone derivatives for treating or preventing diseases associated with iron overload |
| US20040081961A1 (en) * | 2001-05-04 | 2004-04-29 | Delegeane Angelo M | Proteases |
| EP1618881A1 (en) | 2004-07-20 | 2006-01-25 | Santhera Pharmaceuticals (Schweiz) GmbH | Use of non-glucocorticoid steroids for the treatment of muscular dystrophy |
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- 2006-03-20 MX MX2007011571A patent/MX2007011571A/es active IP Right Grant
- 2006-03-20 JP JP2008502302A patent/JP4896123B2/ja not_active Expired - Fee Related
- 2006-03-20 PT PT06723554T patent/PT1861080E/pt unknown
- 2006-03-20 WO PCT/EP2006/002536 patent/WO2006100017A1/en not_active Ceased
- 2006-03-20 US US11/886,388 patent/US7977388B2/en not_active Expired - Fee Related
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- 2006-03-20 DK DK06723554.9T patent/DK1861080T3/da active
- 2006-03-20 NZ NZ561235A patent/NZ561235A/en not_active IP Right Cessation
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- 2006-03-20 EP EP06723554A patent/EP1861080B1/en not_active Expired - Lifetime
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- 2006-03-20 AU AU2006226623A patent/AU2006226623B2/en not_active Ceased
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2007
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- 2010-07-06 CY CY20101100628T patent/CY1110182T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE602006014514D1 (https=) | 2010-07-08 |
| AU2006226623B2 (en) | 2010-04-22 |
| WO2006100017A1 (en) | 2006-09-28 |
| PL1861080T3 (pl) | 2010-10-29 |
| ATE468849T1 (de) | 2010-06-15 |
| PT1861080E (pt) | 2010-06-17 |
| SI1861080T1 (sl) | 2010-08-31 |
| MX2007011571A (es) | 2007-12-06 |
| JP2008533182A (ja) | 2008-08-21 |
| CY1110182T1 (el) | 2015-01-14 |
| US20090012050A1 (en) | 2009-01-08 |
| EP1861080B1 (en) | 2010-05-26 |
| US7977388B2 (en) | 2011-07-12 |
| NZ561235A (en) | 2010-12-24 |
| EP1861080A1 (en) | 2007-12-05 |
| CA2602290A1 (en) | 2006-09-28 |
| DK1861080T3 (da) | 2010-09-06 |
| ES2345353T3 (es) | 2010-09-21 |
| AU2006226623A1 (en) | 2006-09-28 |
| CA2602290C (en) | 2012-01-17 |
| ZA200707833B (en) | 2008-06-25 |
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