JP4854519B2 - 急性肺損傷の治療におけるエアロゾル化アンチトロンビンの使用法 - Google Patents

急性肺損傷の治療におけるエアロゾル化アンチトロンビンの使用法 Download PDF

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JP4854519B2
JP4854519B2 JP2006551170A JP2006551170A JP4854519B2 JP 4854519 B2 JP4854519 B2 JP 4854519B2 JP 2006551170 A JP2006551170 A JP 2006551170A JP 2006551170 A JP2006551170 A JP 2006551170A JP 4854519 B2 JP4854519 B2 JP 4854519B2
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composition according
atiii
lung
lung injury
argatroban
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JP2007518801A5 (enExample
JP2007518801A (ja
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和紀 村上
エンカバータル,ペレンレイ
エイ コックス,ロバート
エイ ホーキンス,ハル
ディー トレイバー,リリアン
エル トレイバー,ダニエル
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ボード オブ リージェンツ ザ ユニヴァーシティ オブ テキサス システム
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2006551170A 2004-01-23 2005-01-14 急性肺損傷の治療におけるエアロゾル化アンチトロンビンの使用法 Expired - Fee Related JP4854519B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US53867804P 2004-01-23 2004-01-23
US60/538,678 2004-01-23
US11/034,590 2005-01-13
US11/034,590 US20050169908A1 (en) 2004-01-23 2005-01-13 Use of aerosolized antithrombin to treat acute lung injury
PCT/US2005/001238 WO2005072139A2 (en) 2004-01-23 2005-01-14 Use of aerosolized antithrombin to treat acute lung injury

Publications (3)

Publication Number Publication Date
JP2007518801A JP2007518801A (ja) 2007-07-12
JP2007518801A5 JP2007518801A5 (enExample) 2008-10-16
JP4854519B2 true JP4854519B2 (ja) 2012-01-18

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JP2006551170A Expired - Fee Related JP4854519B2 (ja) 2004-01-23 2005-01-14 急性肺損傷の治療におけるエアロゾル化アンチトロンビンの使用法

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US (1) US20050169908A1 (enExample)
EP (1) EP1713500A2 (enExample)
JP (1) JP4854519B2 (enExample)
KR (1) KR20060127992A (enExample)
AU (1) AU2005208552A1 (enExample)
CA (1) CA2553758A1 (enExample)
IL (1) IL177028A0 (enExample)
WO (1) WO2005072139A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ535487A (en) * 2002-04-01 2008-12-24 Univ Texas Medical Branch Administration of ATIII by inhalation provides more efficient treatment of lung disorders such as lung inflammation and injury than intravenous administration
US20050192226A1 (en) * 2004-02-20 2005-09-01 Perenlei Enkhbaatar Method of preventing fibrin clots in pulmonary tissue through the use of aerosolized anticoagulants
US20050245444A1 (en) * 2004-04-30 2005-11-03 Yann Echelard Method of using recombinant human antithrombin for neurocognitive disorders
US20060121004A1 (en) * 2004-12-07 2006-06-08 Yann Echelard Methods of reducing the incidence of rejection in tissue transplantation through the use of recombinant human antithrombin
WO2012090067A1 (en) 2010-12-30 2012-07-05 Lfb Biotechnologies Glycols as pathogen inactivating agents
WO2014089327A1 (en) * 2012-12-05 2014-06-12 National Jewish Health Treatment for airway cast obstruction
EP3594230A1 (en) 2013-02-13 2020-01-15 Laboratoire Français du Fractionnement et des Biotechnologies Highly galactosylated anti-tnf-alpha antibodies and uses thereof
WO2014140927A2 (en) 2013-02-13 2014-09-18 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Proteins with modified glycosylation and methods of production thereof
ES2793176T3 (es) 2013-07-05 2020-11-13 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Sa Matriz de cromografía de afinidad
CA2928759A1 (en) 2013-11-04 2015-05-07 Board Of Regents, The University Of Texas System Compositions and methods for administration of an enzyme to a subject's airway
WO2016118625A1 (en) * 2015-01-20 2016-07-28 Incarda Therapeutics, Inc. Unit aerosol doses for anticoagulation
WO2016179447A1 (en) * 2015-05-06 2016-11-10 Board Of Regents, The University Of Texas System Compositions and methods for administration of an enzyme to a subject's airway
FR3038517B1 (fr) 2015-07-06 2020-02-28 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Utilisation de fragments fc modifies en immunotherapie
US11654036B2 (en) 2020-05-26 2023-05-23 Elixir Medical Corporation Anticoagulant compounds and methods and devices for their use

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003084476A2 (en) * 2002-04-01 2003-10-16 Gtc Biotherapeutics, Inc. Treatment of lung disorder

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6127347A (en) * 1994-01-12 2000-10-03 Univ Michigan Non-anticoagulant chemically modified heparinoids for treating hypovolemic shock and related shock syndromes
US5843705A (en) * 1995-02-21 1998-12-01 Genzyme Transgenic Corporation Transgenically produced antithrombin III
US7045585B2 (en) * 1995-11-30 2006-05-16 Hamilton Civic Hospital Research Development Inc. Methods of coating a device using anti-thrombin heparin
US6063593A (en) * 1996-11-12 2000-05-16 University Of Southern California University Park Campus TGFβ1 responsive bone marrow derived cells to express a recombinant protein
US6124257A (en) * 1997-08-28 2000-09-26 Lezdey; John Method of treatment
DE10132307A1 (de) * 2001-07-06 2003-01-30 Aventis Behring Gmbh Arzneizubereitung zur Inhalation von Antithrombin bei entzündlichen Lungenerkrankungen und ARDS
US20050192226A1 (en) * 2004-02-20 2005-09-01 Perenlei Enkhbaatar Method of preventing fibrin clots in pulmonary tissue through the use of aerosolized anticoagulants

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003084476A2 (en) * 2002-04-01 2003-10-16 Gtc Biotherapeutics, Inc. Treatment of lung disorder

Also Published As

Publication number Publication date
JP2007518801A (ja) 2007-07-12
US20050169908A1 (en) 2005-08-04
KR20060127992A (ko) 2006-12-13
IL177028A0 (en) 2006-12-10
WO2005072139A2 (en) 2005-08-11
CA2553758A1 (en) 2005-08-11
WO2005072139A3 (en) 2006-01-05
AU2005208552A1 (en) 2005-08-11
EP1713500A2 (en) 2006-10-25

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