JP4852537B2 - 免疫抑制へテロ環化合物 - Google Patents

免疫抑制へテロ環化合物 Download PDF

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Publication number
JP4852537B2
JP4852537B2 JP2007514067A JP2007514067A JP4852537B2 JP 4852537 B2 JP4852537 B2 JP 4852537B2 JP 2007514067 A JP2007514067 A JP 2007514067A JP 2007514067 A JP2007514067 A JP 2007514067A JP 4852537 B2 JP4852537 B2 JP 4852537B2
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JP
Japan
Prior art keywords
group
formula
optionally substituted
methyl
ethyl
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2007514067A
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English (en)
Japanese (ja)
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JP2008500314A (ja
JP2008500314A5 (https=
Inventor
マシューズ,イアン,リチャード
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Medigene Ltd
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Medigene Ltd
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Publication of JP2008500314A publication Critical patent/JP2008500314A/ja
Publication of JP2008500314A5 publication Critical patent/JP2008500314A5/ja
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Publication of JP4852537B2 publication Critical patent/JP4852537B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2007514067A 2004-05-26 2005-04-26 免疫抑制へテロ環化合物 Expired - Fee Related JP4852537B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0411770.1 2004-05-26
GBGB0411770.1A GB0411770D0 (en) 2004-05-26 2004-05-26 Immuno inhibitory heterocyclic compouds
PCT/GB2005/001583 WO2005116033A1 (en) 2004-05-26 2005-04-26 Immuno inhibitory heterocyclic compounds

Publications (3)

Publication Number Publication Date
JP2008500314A JP2008500314A (ja) 2008-01-10
JP2008500314A5 JP2008500314A5 (https=) 2008-06-26
JP4852537B2 true JP4852537B2 (ja) 2012-01-11

Family

ID=32671106

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007514067A Expired - Fee Related JP4852537B2 (ja) 2004-05-26 2005-04-26 免疫抑制へテロ環化合物

Country Status (7)

Country Link
US (1) US7566713B2 (https=)
EP (1) EP1753765B1 (https=)
JP (1) JP4852537B2 (https=)
AT (1) ATE501146T1 (https=)
DE (1) DE602005026805D1 (https=)
GB (1) GB0411770D0 (https=)
WO (1) WO2005116033A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2284172A1 (en) 2003-03-14 2011-02-16 MediGene Ltd. Immunomodulating heterocyclic compounds
ES2315695T3 (es) 2004-08-09 2009-04-01 Medigene Ltd. Oxopirazolocinolinas inmunomoduladoras como inhibidores de moleculas cd80.
GB0603522D0 (en) * 2006-02-22 2006-04-05 Avidex Ltd Kinase inhibition
EP2883883A1 (en) 2013-12-16 2015-06-17 Cardio3 Biosciences S.A. Therapeutic targets and agents useful in treating ischemia reperfusion injury

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000506884A (ja) * 1996-03-20 2000-06-06 アストラ・フアーマシユウテイカルズ・リミテツド 医薬的に有用な化合物
JP2002507208A (ja) * 1997-06-27 2002-03-05 メルク シヤープ エンド ドーム リミテツド Gaba−a受容体リガンドとしての三環ピラゾロ−ピリダジノン類似体
WO2003004495A1 (en) * 2001-07-04 2003-01-16 Active Biotech Ab Novel immunomodulating compounds
WO2004081011A1 (en) * 2003-03-14 2004-09-23 Avidex Limited Immunomodulating heterocyclic compounds

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000506884A (ja) * 1996-03-20 2000-06-06 アストラ・フアーマシユウテイカルズ・リミテツド 医薬的に有用な化合物
JP2002507208A (ja) * 1997-06-27 2002-03-05 メルク シヤープ エンド ドーム リミテツド Gaba−a受容体リガンドとしての三環ピラゾロ−ピリダジノン類似体
WO2003004495A1 (en) * 2001-07-04 2003-01-16 Active Biotech Ab Novel immunomodulating compounds
WO2004081011A1 (en) * 2003-03-14 2004-09-23 Avidex Limited Immunomodulating heterocyclic compounds

Also Published As

Publication number Publication date
EP1753765B1 (en) 2011-03-09
EP1753765A1 (en) 2007-02-21
JP2008500314A (ja) 2008-01-10
DE602005026805D1 (de) 2011-04-21
WO2005116033A1 (en) 2005-12-08
ATE501146T1 (de) 2011-03-15
US7566713B2 (en) 2009-07-28
US20080021033A1 (en) 2008-01-24
GB0411770D0 (en) 2004-06-30

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