JP4849337B2 - Cardiotomy filter and blood reservoir - Google Patents

Description

  The present invention relates to a cardiotomy filter used for filtering intracardiac blood in an extracorporeal blood circulation circuit used when performing cardiopulmonary surgery or the like. The present invention also relates to a blood reservoir that contains this cardiotomy filter and temporarily stores blood in extracorporeal circulation.

  When performing cardiac surgery or the like, an extracorporeal blood circulation circuit including a blood pump or an artificial lung for substituting the functions of a patient's heart and lungs is used. The extracorporeal blood circulation circuit temporarily stores venous blood removed from the patient's veins to adjust the blood volume of the circulation circuit (sometimes called a “venous blood reservoir”), A blood reservoir (sometimes referred to as “intracardiac blood reservoir”) is provided for aspirating, collecting, and temporarily storing blood (intracardiac blood) overflowing in the operative field. Intracardiac blood contains more foreign matter and bubbles such as meat pieces, fat, and blood clots than venous blood, so the intracardiac blood reservoir has a filtration layer for removing foreign matter and air bubbles are eliminated. A cardiotomy filter comprising a defoaming layer is provided.

  An example of a conventional cardiotomy filter is shown in FIGS. 13 (A) and 13 (B). 13A is a side cross-sectional view, and FIG. 13B is a cross-sectional view taken along line 13B-13B in FIG. 13A (see, for example, Patent Documents 1 to 3).

  The cardiotomy filter 100 includes a filtration layer 110 having a substantially cylindrical shape as a whole, and a defoaming layer 120 disposed inside the filtration layer 110 and having a substantially cylindrical shape. Resin plates 131 and 132 having a substantially disc shape are bonded to the upper and lower edges of the filtration layer 110. The defoaming layer 120 is held by being bonded to the upper resin plate 131. A through hole 133 through which blood flows is formed in the center of the upper resin plate 131.

  As shown in FIG. 13C, the filtration layer 110 includes a filter member 111 in which a screen filter 112 and a pair of support members 113a and 113b sandwiching the screen filter 112 are laminated. The filter layer 110 is formed by pleating the rectangular filter member 111 along the short side direction, sealing the pair of short sides, and joining them in an annular shape. A resin mesh filter is used as the screen filter 112. As the support members 113a and 113b, resin mesh members having higher mechanical strength than the screen filter 112 and having relatively large openings are used.

  As the antifoaming layer 120, a foam made of polyurethane having open cells coated with an antifoaming agent such as silicone is used.

The blood mixed with bubbles and foreign matters flows into the cardiotomy filter 100 through the through hole 133 of the upper resin plate 131. Air bubbles gather near the liquid surface of blood due to buoyancy, and come into contact with the defoaming layer 120 and burst. Foreign matter is captured by the filtration layer 110. Thus, the blood from which bubbles and foreign matters have been removed flows out of the cardiotomy filter 100 through the filtration layer 110.
JP 2001-204815 A Japanese Unexamined Patent Publication No. 63-102864 JP-A-62-258673

  In the conventional cardiotomy filter described above, the lower resin plate 132 is provided to maintain the overall shape of the filter member 111. However, since this resin plate 132 does not have a filter function, it has the following problems.

  First, the initial liquid permeability is poor. The initial liquid permeability depends on the amount of filling liquid required until the filling liquid begins to flow out of the filtration layer 110 when the filling liquid is first introduced into the cardiotomy filter through the through hole 133 of the upper resin plate 131. To be judged. If the initial liquid permeability is poor, a large amount of filling liquid and time are required for the filling liquid to pass through the cardiotomy filter. Accordingly, the amount of blood necessary for filling the extracorporeal blood circulation circuit, that is, the circuit filling amount is increased. An increase in the circuit filling amount, that is, the blood volume in the extracorporeal blood circulation circuit is a burden on the patient because the blood moves from the patient's body to the outside of the body. In addition, when chemical liquid is mixed into the blood in the blood reservoir through the cardiotomy filter, if the initial liquid permeability is inferior, the chemical liquid flows out of the cardiotomy filter and enters the blood stored in the blood reservoir. Takes a lot of time, which is disadvantageous when prompt treatment is required.

  Secondly, the dynamic filling amount increases. The dynamic filling amount is the total amount of the static filling amount existing before circulation and the extra liquid amount necessary for circulation, and includes the amount of liquid remaining in the filter. When the dynamic filling amount is large, not only the circuit filling amount is increased, but also the response of the increase / decrease of the blood storage amount in the blood reservoir becomes dull and the burden on the operator is increased in controlling and adjusting the blood level. .

  Third, the amount of residual blood is large. Residual blood refers to blood remaining in the cardiotomy filter after stopping extracorporeal blood circulation. When the residual blood volume is large, the amount of blood returned to the patient decreases, and the burden on the patient increases.

  An object of the present invention is to provide a cardiotomy filter with improved initial liquid permeability, dynamic filling amount, and residual blood volume, and a blood reservoir equipped with the cardiotomy filter.

  The cardiotomy filter of this invention is equipped with the filter member which consists of a pair of support material arrange | positioned on both sides of the screen filter and the said screen filter. The filter member is pleated along a first direction, bent along a second direction intersecting the first direction, and a pair of edges of the filter member intersecting the second direction are respectively sealed. ing.

  The blood reservoir of the present invention includes the cardiotomy filter of the present invention.

  According to the present invention, it is possible to provide a cardiotomy filter with improved initial liquid permeability, dynamic filling amount, and residual blood volume, and a blood reservoir equipped with the same.

  It is preferable that the cardiotomy filter of the present invention further includes a resin plate adhered to an edge of the filter member opposite to the bent side. Thereby, the shape retention characteristic of the cardiotomy filter is improved.

  Moreover, it is preferable that the cardiotomy filter of the present invention further includes a defoaming layer inside the filter member. Thereby, the defoaming characteristic of the bubble in the blood can be improved.

  Hereinafter, the cardiotomy filter and blood reservoir of the present invention will be described in detail with reference to the drawings.

  1A is a perspective view of a cardiotomy filter 1 according to an embodiment of the present invention, FIG. 1B is a side view thereof, and FIG. 1C is a top view thereof. The cardiotomy filter 1 of the present embodiment includes a filter member 11 that is pleated along the first direction 91 shown in FIG. The filter member 11 has a bent portion 11 a that is bent along a second direction 92 that intersects the first direction 91. Further, the filter member 11 is sealed by a pair of end edges 11b and 11c intersecting the second direction 92, respectively. The filter member 11 has a three-layer laminated structure including a screen filter and a pair of support members sandwiching the screen filter.

  Since the screen filter is held between a pair of support members having relatively high mechanical strength, the screen filter can be maintained in a desired shape.

  Moreover, since many pleats are formed in the filter member 11, the surface area of the filter member 11 increases, filtration efficiency improves, and filter life can be lengthened.

  A method for manufacturing the cardiotomy filter 1 will be described below.

  First, as shown in FIG. 2, the support members 13 a and 13 b are overlapped on both sides of the screen filter 12 to form a rectangular filter member 11 having a three-layer laminated structure.

  Next, as shown in FIG. 3, a large number of pleats are formed along a first direction 91 parallel to one side of the rectangular filter member 11. That is, the mountain fold and the valley fold are repeatedly performed along a direction parallel to the first direction 91 at a constant pitch.

  Next, the filter member 11 is moved along the fold line 15 indicated by a two-dot chain line that passes through an intermediate position in the first direction 91 of the filter member 11 and is parallel to the second direction 92 orthogonal to the first direction 91. Bend in the direction of 16b. At this time, for example, the linear one end edge of the jig made of a hard material such as resin or metal is pressed against the filter member 11 along the fold line 15, and all the peaks (ridges) of the pleats in contact with the jig are moved to the first position. If it is bent while being displaced to either one of the two directions 92, it can be bent easily and with good appearance.

Next, both end edges in the second direction of the filter member 11 are sealed and joined. That is, of the edge 11b located on one side in the second direction 92, the edge 11b ₁ located on one side with respect to the fold line 15 and the short edge 11b ₂ located on the other side. Overlap and seal. The edge 11c located on the other side in the second direction 92 is similarly sealed. The sealing method is not particularly limited and may be appropriately selected in consideration of the material of the filter member 11 and the like. For example, a heat sealing method can be used. At this time, a material for improving the sealing performance such as vinyl chloride may be sandwiched between _two members to be sealed (for example, the end edge portion 11b ₁ and the short edge portion 11b ₂ ).

  Thus, the cardiotomy filter 1 having a bag shape as a whole (or a shape similar to a paper coffee filter used for coffee extraction) shown in FIGS. 1 (A) to 1 (C) is obtained. Can do.

  In the present invention, the screen filter 12 has a function of capturing and removing foreign substances in the blood when the blood passes. Further, it may have a function of trapping bubbles. There is no restriction | limiting in particular as the screen filter 12 which has such a function, The well-known screen filter used for the conventional cardiotomy filter can be selected arbitrarily and can be used. For example, a mesh filter made of a resin material such as polyester, nylon, or polypropylene can be used. The pore diameter is not particularly limited, but is preferably 20 to 50 μm.

  The support materials 13a and 13b are used to maintain the shape of the screen filter 12. Therefore, it is necessary to have higher mechanical strength than the screen filter 12. There is no restriction | limiting in particular as support material 13a, 13b, The well-known support material used for the conventional cardiotomy filter can be selected arbitrarily and can be used. For example, a mesh member made of a material having good heat sealability such as polypropylene can be used. The hole diameters of the support members 13a and 13b are preferably larger than the hole diameter of the screen filter 12.

  The screen filter 12 and / or the support materials 13a and 13b may be coated with an antifoaming agent (for example, silicone) to give a bubble defoaming function.

  4A is a side view of a cardiotomy filter 2 according to another embodiment of the present invention, FIG. 4B is a cross-sectional view taken along line 4B-4B in FIG. 4A, and FIG. (C) is arrow sectional drawing along the 4C-4C line | wire of FIG. 4 (A). The cardiotomy filter 2 shown in FIGS. 4 (A) to 4 (C) has a resin plate 20 and a defoaming layer 27 as compared to the cardiotomy filter 1 shown in FIGS. 1 (A) to 1 (C). Is different in that it is further provided. 4 (A) to 4 (C), members having the same functions as those shown in FIGS. 1 (A) to 1 (C) are denoted by the same reference numerals, and detailed descriptions thereof are given. Omitted.

  The resin plate 20 is bonded to the edge of the filter member 11 on the side opposite to the bent portion 11a (upper side) over the entire circumference. The material of the resin plate 20 is not particularly limited, but for example, an adhesive such as polyurethane can be used. In the example shown in FIGS. 4A and 4B, the planar shape of the resin plate 20 is an oval shape (that is, a track (running track) shape of an athletic field), but is not limited to this. Arbitrary shapes such as shape, circle and rectangle can be selected. By providing the resin plate 20, the shape retention characteristics of the filter member 11 are improved. The resin plate 20 is formed with a through hole 23 through which blood flows.

  As shown in FIG. 4C, the defoaming layer 27 is provided in an annular shape along the inner surface of the filter member 11 inside the filter member 11. Since the filter member 11 is pleated, a gap 28 is formed between the filter member 11 and the defoaming layer 27. As shown in FIG. 4B, the defoaming layer 27 is provided only in the upper region of the filter member 11 in the vertical direction, and the upper edge of the defoaming layer 27 is bonded to the resin plate 20. The defoaming layer 27 is held on the resin plate 20. The defoaming layer 27 is not particularly limited as long as it has a function of breaking bubbles in contact with it, and a known defoaming layer used in a conventional cardiotomy filter is arbitrarily selected and used. Can do. For example, a material in which the surface of polyurethane as a base layer is coated with silicone as an antifoaming agent can be used. Moreover, as a form, the foam, woven fabric, knitted fabric, nonwoven fabric, etc. which have open cells can be used. The defoaming layer 27 may be a single layer or may have a laminated structure of two or more layers. In addition, when the filter member 11 has a defoaming function, the defoaming layer 27 can be omitted.

  Next, an example of a blood reservoir equipped with the cardiotomy filter 2 of the present invention shown in FIGS. 4 (A) to 4 (C) will be described.

  FIG. 5 is a perspective view of an example of a blood reservoir, and FIG. 6 is a side sectional view thereof. The blood reservoir 5 includes a housing 30 including a housing main body 31 and a lid 36 placed on top of the housing main body 31.

  The housing body 31 includes a blood storage part 32 that is formed so that a part of the bottom surface of the housing body protrudes downward, and a blood outflow port 33 that is provided at the lower end of the blood storage part 32 and from which blood flows out. A fixing hole 34 for holding the blood reservoir 5 is formed on the lower surface of the housing main body 31 by inserting the upper end of a support column erected in the operating room.

  A blood inflow port 60 through which venous blood flows in and a plurality of intracardiac blood inflow ports 50 through which intracardiac blood flows in are attached to the lid body 36. Further, the lid body 36 has a plurality of chemical solution injection ports 71 and 72 for mixing a chemical solution or the like into the blood, a large amount of chemical solution is urgently mixed into the blood, or the filter member 11 of the cardiotomy filter 2 is connected to the filter. A service port 73 for allowing blood that has passed through an alternative cardiotomy filter to flow in when it cannot be used due to clogging, an exhaust port 74 for adjusting the pressure in the blood reservoir 5, and in the blood reservoir 5 A pressure regulating valve 75 or the like for preventing the pressure from becoming an abnormal positive pressure or negative pressure is provided. The blood inlet port 60 is pierced with a temperature probe 61 for measuring the temperature of venous blood.

  A blood removal line tube of an extracorporeal blood circulation circuit is connected to the blood inflow port 60, and an intracardiac blood suction line tube is connected to the intracardiac blood inflow port 50. The blood outlet port 33 is connected to a tube of a blood supply line of the extracorporeal blood circulation circuit. The chemical liquid injection ports 71 and 72 are connected to a chemical liquid injection line tube connected to a predetermined chemical liquid pack. The medicinal solution flowing in from the medicinal solution injection port 71 does not pass through the cardiotomy filter 2 but flows into the blood storage unit 32, and the medicinal solution flowing in from the medicinal solution injection port 72 passes through the cardiotomy filter 2 and then into the blood storage unit 32. Flow into. Various lines of tubes are connected to the service port 73. The temperature probe 61 is connected to electrical wiring connected to the temperature measuring device.

  A support member 40 that holds a venous blood filtration network 47 is accommodated in the housing 30. FIG. 7 is a perspective view showing the support member 40 in a state where the venous blood filtration network 47 is not held. The support member 40 includes a cup-shaped portion 41 having a substantially bowl shape and a frame-shaped portion 45 formed of a lattice-shaped frame formed on one side surface of the cup-shaped portion 41. A groove 43 is formed on the bottom surface of the cup-shaped portion 41. The frame-like portion 45 extends below the cup-like portion 41 so as to be inserted into the blood reservoir 32 of the housing body 31. A venous blood filtration network 47 is fixedly held on the frame-shaped portion 45 so as to close the opening formed on the side surface of the frame-shaped portion 45. The venous blood filtration network 47 extends over almost the entire range of the frame-shaped portion 45 in the vertical direction, and the lower end thereof reaches the vicinity of the blood outflow port 33.

  As long as the venous blood filtration network 47 has a function as a filter for removing foreign substances and bubbles in the blood, there is no particular limitation on the configuration and material thereof, and a known one can be appropriately selected and used. . For example, a screen filter having a large number of fine openings can be used as the venous blood filtration network 47.

  The blood inflow port 60 and the upper end of the venous blood introduction tube 80 are connected via the lid 36. The venous blood introduction tube 80 is fitted into the groove 43 of the cup-shaped portion 41 and guided inside the support member 40 from the cup-shaped portion 41 to the frame-shaped portion 45, and the opening at the lower end thereof is the lowest blood in the blood reservoir 5. It is located below the surface level B.

  The cardiotomy filter 2 is disposed in the support member 40 below the intracardiac blood entry port 50. The outflow end 53 of the intracardiac blood inflow port 50 is inserted into a through hole 23 formed in the resin plate 20 of the cardiotomy filter 2. The bent portion 11 a at the lower end of the filter member 11 is in contact with the bottom surface of the cup-shaped portion 41, thereby reducing foaming of blood flowing out from the cardiotomy filter 2.

  The flow of blood in the blood reservoir 5 will be briefly described. The venous blood removed from the patient's vein passes through the blood inflow port 60 and the venous blood introduction tube 80 in order, flows out from the opening at the lower end of the venous blood introduction tube 80, passes through the venous blood filtration network 47, It flows out from the blood outflow port 33. In addition, the intracardiac blood sucked from the patient's operative field sequentially passes through the intracardiac blood flow entry port 50 and the cardiotomy filter 2, flows out into the support member 40, passes through the venous blood filtration network 47, It flows out from the blood outflow port 33. In this process, blood is temporarily stored in the blood storage unit 32.

  The embodiment shown above is an example, and the present invention is not limited to this.

  In the cardiotomy filter 2 shown in FIGS. 4A to 4C, the defoaming layer 27 is held by being bonded to the resin plate 20, but the method of holding the defoaming layer 27 is not limited to this. . For example, the defoaming layer 27 may be held by a jig provided at the lower end of the defoaming layer 27 so that the defoaming layer 27 does not descend with respect to the filter member 11.

  The cardiotomy filters 1 and 2 of the present invention are not limited to the blood reservoir 5 shown in FIGS. 5 to 7, and can be mounted in any known blood reservoir. For example, the blood reservoir 5 shown in FIGS. 5 to 7 is an intracardiac blood reservoir integrated venous blood reservoir into which venous blood and intracardiac blood flow, but an intracardiac blood reservoir to which venous blood does not flow. Of course, it is possible to install it in

(Example)
The cardiotomy filter based on the Example corresponding to this invention shown to FIG. 8 (A)-FIG. 8 (B) was created. This cardiotomy filter differs from the cardiotomy filter 2 shown in FIGS. 4A to 4C in that a cylindrical introduction tube 25 is provided in a through hole 23 formed in the resin plate 20. . 8 (A) to 8 (B), members having the same functions as those shown in FIGS. 4 (A) to 4 (C) are assigned the same reference numerals and detailed descriptions thereof are given. Omitted.

  The cardiotomy filter of an Example was manufactured as follows.

  As shown in FIG. 2, support members 13 a and 13 b are overlapped on both sides of the screen filter 12 to form a rectangular filter member 11 having a three-layer structure. As the screen filter 12, a mesh filter made of polyethylene terephthalate (PET) and having a pore diameter of 40 μm was used. As the support materials 13a and 13b, meshes made of polypropylene and having a hole diameter of 1 mm were used. As shown in FIG. 3, a large number of pleats are formed on the filter member 11 by repeating mountain folding and valley folding along the first direction 91 at a pitch of 10 mm, and then the filter member 11 is moved in the second direction 92. The both end edges 11b and 11c of the filter member 11 were heat-sealed. One end edge of the defoaming layer 27 and the end opposite to the bent portion 11a of the filter member 11 are immersed in the polyurethane adhesive poured into the oval mold, and the polyurethane adhesive is cured in this state. A resin plate 20 was formed. As the defoaming layer 27, a polyurethane foam having a continuous cell formed with silicone coated on the surface was used. The planar view shape of the edge bonded to the resin plate 20 of the filter member 11 was an oval as a whole. The major axis direction of the resin plate 20 and the extending direction of the bent portion 11a were matched. Thereafter, a cylindrical introduction tube 25 was inserted into the through hole 23 of the resin plate 20 and fixed.

  As shown in FIGS. 8A to 8B, the distance (filter member height) from the lower surface of the resin plate 20 to the bent portion 11a of the filter member 11 is A, and the defoaming from the lower surface of the resin plate 20 The distance to the lower end of the layer 27 (defoaming layer height) is C, the distance from the lower surface of the resin plate 20 to the lower end of the introduction tube 25 (introduction tube length) is D, and the filter member 11 on the lower surface of the resin plate 20 The outer dimension in the minor axis direction is E, and the outer dimension in the major axis direction is F. The inner surface area of the filter member 11 is S1, and the inner surface area of the defoaming layer 27 is S2. Table 1 summarizes the dimensions of each part.

(Comparative example)
The cardiotomy filter based on the comparative example shown to FIG. 9 (A)-FIG. 9 (B) was created. This cardiotomy filter is the cardiotomy filter 100 shown in FIGS. 13A to 13C in that a cylindrical introduction tube 135 is provided in a through hole 133 formed in the upper resin plate 131. And different. 9 (A) to 9 (B), members having the same functions as those shown in FIGS. 13 (A) to 13 (C) are assigned the same reference numerals, and detailed descriptions thereof will be given. Omitted.

  The cardiotomy filter of the comparative example was manufactured as follows.

  As shown in FIG. 13C, the support members 113a and 113b were overlapped on both sides of the screen filter 112 in the same manner as in the example to form a rectangular filter member 111 having a three-layer structure. As the screen filter 112 and the support materials 113a and 113b, the same ones as in the example were used. In the obtained filter member 111, a number of pleats are formed by repeating a mountain fold and a valley fold along the short side direction at a pitch of 10 mm, and then the filter member 111 is sealed between its pair of short sides. Joined in a ring. One end edge of the defoaming layer 120 and one end edge of the filter member 111 were immersed in the polyurethane adhesive poured into the circular mold, and the polyurethane adhesive was cured in this state to form the upper resin plate 131. As the defoaming layer 120, the same material as that of the example was used except that the overall shape was a cylindrical shape. Next, the other end edge of the filter member 111 was immersed in a polyurethane adhesive poured into a circular mold, and the polyurethane adhesive was cured in this state to form the lower resin plate 132. The shape of the filter member 111 in plan view is circular as a whole. Thereafter, a cylindrical introduction tube 135 was inserted into the through hole 133 of the resin plate 131 and fixed.

  As shown in FIGS. 9A to 9B, the distance (filter member height) between the upper and lower resin plates 131 and 132 is A, and the lower surface of the upper resin plate 131 to the lower end of the defoaming layer 120. The distance (defoaming layer height) is C, the distance from the lower surface of the upper resin plate 131 to the lower end of the introduction pipe 135 (introduction pipe length) is D, and the outer dimensions of the filter member 111 in two orthogonal directions are E and F And The inner surface area of the filter member 111 is S1, and the inner surface area of the defoaming layer 120 is S2. Table 1 summarizes the dimensions of each part.

(Evaluation)
The cardiotomy filters of Examples and Comparative Examples were evaluated for the following items.

1. Initial liquid permeability A physiological saline was injected from the introduction tube using a syringe, and the amount of physiological saline injected until the physiological saline passed through the filter member and flowed out was measured.

  The results are shown in FIG. As shown in FIG. 10, the example was excellent in initial liquid permeability compared with the comparative example. Therefore, by using the cardiotomy filter of the embodiment, the circuit filling amount of the extracorporeal blood circulation circuit can be reduced. Moreover, it becomes possible to mix a chemical in the blood in the blood reservoir through the cardiotomy filter in a short time.

2. Dynamic filling amount A cardiotomy filter was installed in a blood reservoir, and blood was circulated stably at a predetermined flow rate and blood storage level. Thereafter, the increase in the blood storage level in the blood reservoir when the blood circulation was stopped was measured. The blood flow rate was measured by changing the blood flow rate in four ways: 0.5, 1.0, 1.5, and 2.0 cm ³ / min.

  The results are shown in FIG. As shown in FIG. 11, regardless of the blood flow rate, the example had a smaller amount of dynamic filling than the comparative example. Therefore, by using the cardiotomy filter of the embodiment, the circuit filling amount of the extracorporeal blood circulation circuit can be reduced.

3. Residual blood volume A cardiotomy filter was mounted in a blood reservoir, and after circulating blood at a designed maximum flow rate of 2 × 10 ³ cm ³ / min, blood circulation was stopped. The weight of the cardiotomy filter was measured before blood circulation and at the time when blood flowed out from the cardiotomy filter after blood circulation was stopped, and the difference was determined. And the obtained weight difference was converted into the volume.

  The results are shown in FIG. As shown in FIG. 12, the amount of residual blood was less in the example than in the comparative example. Therefore, by using the cardiotomy filter of the embodiment, the amount of blood returned to the patient can be increased and the burden on the patient can be reduced.

4). Anti-foaming property A cardiotomy filter is installed in the blood reservoir, and blood mixed with air is circulated to visually observe the presence of bubbles in the blood that has passed through the filter member. The pressure of the layer was measured. If the pressure inside the cardiotomy filter becomes positive, it may cause problems such as difficulty in injecting blood or chemicals into the cardiotomy filter.

  As a result, no significant difference was observed between the example and the comparative example, and both the example and the comparative example had good defoaming characteristics.

  As mentioned above, it was confirmed that the cardiotomy filter based on the Example corresponding to this invention shows a favorable characteristic in initial stage liquid permeability, dynamic filling amount, and residual blood volume.

  INDUSTRIAL APPLICABILITY The present invention can be widely used as a cardiotomy filter provided in an extracorporeal blood circulation circuit used when performing cardiopulmonary surgery or the like and a blood reservoir equipped with the cardiotomy filter.

1A is a perspective view of a cardiotomy filter according to an embodiment of the present invention, FIG. 1B is a side view thereof, and FIG. 1C is a top view thereof. FIG. 2 is a perspective view showing a process for manufacturing a cardiotomy filter according to an embodiment of the present invention. FIG. 3 is a perspective view showing one process for manufacturing a cardiotomy filter according to an embodiment of the present invention. 4A is a side view of a cardiotomy filter according to another embodiment of the present invention, FIG. 4B is a cross-sectional view taken along line 4B-4B in FIG. 4A, and FIG. FIG. 4C is a cross-sectional view taken along line 4C-4C in FIG. FIG. 5 is a perspective view of an example of a blood reservoir equipped with the cardiotomy filter of the present invention shown in FIGS. 4 (A) to 4 (C). FIG. 6 is a side cross-sectional view of an example of a blood reservoir equipped with the cardiotomy filter of the present invention shown in FIGS. 4 (A) to 4 (C). FIG. 7 is a perspective view of a support member installed in the blood reservoir of the present invention shown in FIG. 8A is a side view of the cardiotomy filter according to the embodiment, and FIG. 8B is a cross-sectional view taken along line 8B-8B in FIG. 8A. 9A is a side cross-sectional view of a cardiotomy filter according to a comparative example, and FIG. 9B is a cross-sectional view taken along line 9B-9B of FIG. 9A. FIG. 10 is a diagram showing measurement results of initial liquid permeability of the cardiotomy filters of Examples and Comparative Examples. FIG. 11 is a diagram showing the measurement results of the dynamic filling amount of the cardiotomy filter of the example and the comparative example. FIG. 12 is a diagram showing the measurement results of the residual blood volume of the cardiotomy filters of Examples and Comparative Examples. 13A is a side sectional view of an example of a conventional cardiotomy filter, FIG. 13B is a sectional view taken along line 13B-13B in FIG. 13A, and FIG. 13C is a conventional sectional view. It is an expanded sectional view of a filter member which constitutes a cardiotomy filter.

Explanation of symbols

1, 2 Cardiotomy filter 5 Blood reservoir 11 Filter member 11a Bending portion 11b, 11c Edge 12 Screen filter 13a, 13b Support material 20 Resin plate 23 Through hole 27 Defoaming layer 91 First direction 92 Second direction

Claims (4)

A filter member comprising a screen filter and a pair of support members arranged with the screen filter interposed therebetween,
The filter member is pleated along a first direction, bent along a second direction intersecting the first direction, and a pair of edges of the filter member intersecting the second direction are respectively sealed. A cardiotomy filter characterized by   Furthermore, the cardiotomy filter of Claim 1 provided with the resin board adhere | attached on the edge on the opposite side to the said bent side of the said filter member.   The cardiotomy filter according to claim 1, further comprising a defoaming layer inside the filter member.   A blood reservoir equipped with the cardiotomy filter according to any one of claims 1 to 3.

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