JP4842686B2 - Topical skin preparation - Google Patents
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- JP4842686B2 JP4842686B2 JP2006104725A JP2006104725A JP4842686B2 JP 4842686 B2 JP4842686 B2 JP 4842686B2 JP 2006104725 A JP2006104725 A JP 2006104725A JP 2006104725 A JP2006104725 A JP 2006104725A JP 4842686 B2 JP4842686 B2 JP 4842686B2
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- 238000002360 preparation method Methods 0.000 title claims description 23
- 230000000699 topical effect Effects 0.000 title description 3
- 229920001577 copolymer Polymers 0.000 claims description 9
- PQUXFUBNSYCQAL-UHFFFAOYSA-N 1-(2,3-difluorophenyl)ethanone Chemical compound CC(=O)C1=CC=CC(F)=C1F PQUXFUBNSYCQAL-UHFFFAOYSA-N 0.000 claims description 8
- 229940047670 sodium acrylate Drugs 0.000 claims description 8
- XHZPRMZZQOIPDS-UHFFFAOYSA-N 2-Methyl-2-[(1-oxo-2-propenyl)amino]-1-propanesulfonic acid Chemical compound OS(=O)(=O)CC(C)(C)NC(=O)C=C XHZPRMZZQOIPDS-UHFFFAOYSA-N 0.000 claims description 6
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 4
- 125000000217 alkyl group Chemical group 0.000 claims description 3
- 125000004432 carbon atom Chemical group C* 0.000 claims description 3
- 229910052739 hydrogen Inorganic materials 0.000 claims description 3
- 239000001257 hydrogen Substances 0.000 claims description 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 2
- 229920001296 polysiloxane Polymers 0.000 description 16
- 238000003860 storage Methods 0.000 description 11
- 239000000203 mixture Substances 0.000 description 9
- 238000002156 mixing Methods 0.000 description 7
- 239000006071 cream Substances 0.000 description 6
- 239000002537 cosmetic Substances 0.000 description 5
- 229920000642 polymer Polymers 0.000 description 5
- 229920002545 silicone oil Polymers 0.000 description 5
- 238000003892 spreading Methods 0.000 description 5
- 229920002125 Sokalan® Polymers 0.000 description 4
- 150000001298 alcohols Chemical class 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 4
- 239000000839 emulsion Substances 0.000 description 4
- 238000011156 evaluation Methods 0.000 description 4
- 239000003205 fragrance Substances 0.000 description 4
- 230000001771 impaired effect Effects 0.000 description 4
- 239000004094 surface-active agent Substances 0.000 description 4
- 239000002562 thickening agent Substances 0.000 description 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 239000003921 oil Substances 0.000 description 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- BANXPJUEBPWEOT-UHFFFAOYSA-N 2-methyl-Pentadecane Chemical compound CCCCCCCCCCCCCC(C)C BANXPJUEBPWEOT-UHFFFAOYSA-N 0.000 description 2
- 241000272185 Falco Species 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- KGLAXXUXWSFQMO-UHFFFAOYSA-N [Na].C(C=C)(=O)C(N(C)C)CS(=O)(=O)O Chemical compound [Na].C(C=C)(=O)C(N(C)C)CS(=O)(=O)O KGLAXXUXWSFQMO-UHFFFAOYSA-N 0.000 description 2
- 238000013329 compounding Methods 0.000 description 2
- -1 gums Substances 0.000 description 2
- 239000000419 plant extract Substances 0.000 description 2
- 238000006116 polymerization reaction Methods 0.000 description 2
- 230000001953 sensory effect Effects 0.000 description 2
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 229940043268 2,2,4,4,6,8,8-heptamethylnonane Drugs 0.000 description 1
- DGSZGZSCHSQXFV-UHFFFAOYSA-N 2,3-bis(2-ethylhexanoyloxy)propyl 2-ethylhexanoate Chemical compound CCCCC(CC)C(=O)OCC(OC(=O)C(CC)CCCC)COC(=O)C(CC)CCCC DGSZGZSCHSQXFV-UHFFFAOYSA-N 0.000 description 1
- IRLPACMLTUPBCL-KQYNXXCUSA-N 5'-adenylyl sulfate Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP(O)(=O)OS(O)(=O)=O)[C@@H](O)[C@H]1O IRLPACMLTUPBCL-KQYNXXCUSA-N 0.000 description 1
- NWGKJDSIEKMTRX-AAZCQSIUSA-N Sorbitan monooleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O NWGKJDSIEKMTRX-AAZCQSIUSA-N 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 239000002280 amphoteric surfactant Substances 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 239000013065 commercial product Substances 0.000 description 1
- 239000000306 component Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000008406 cosmetic ingredient Substances 0.000 description 1
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000001804 emulsifying effect Effects 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 239000008269 hand cream Substances 0.000 description 1
- KUVMKLCGXIYSNH-UHFFFAOYSA-N isopentadecane Natural products CCCCCCCCCCCCC(C)C KUVMKLCGXIYSNH-UHFFFAOYSA-N 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229940068968 polysorbate 80 Drugs 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000002453 shampoo Substances 0.000 description 1
- 229920005573 silicon-containing polymer Polymers 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 229950004959 sorbitan oleate Drugs 0.000 description 1
- 229940032094 squalane Drugs 0.000 description 1
- WNIFXKPDILJURQ-UHFFFAOYSA-N stearyl glycyrrhizinate Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C)CCC(C(=O)OCCCCCCCCCCCCCCCCCC)(C)CC5C4=CC(=O)C3C21C WNIFXKPDILJURQ-UHFFFAOYSA-N 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 125000003944 tolyl group Chemical group 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Description
本発明は、塗布時にのびが良く、べたつかず、皮膚にしっとりとした感触を与え、且つ保存安定性に優れた皮膚外用剤に関する。 The present invention relates to an external preparation for skin which has good spreading at the time of application, is not sticky, gives a moist feel to the skin, and has excellent storage stability.
従来、クリーム、乳液等の皮膚外用剤には、皮膚に潤いを与えたり、感触を変化させる目的で各種油剤の配合がなされてきた。中でもシリコーン油はすべりの良い感触から汎用されている。そしてシリコーン油を安定に配合するため、界面活性剤を多量に用いて乳化したり、カルビキシビニルポリマー等の高分子増粘剤を用いて分散する技術が用いられてきた。しかしながら界面活性剤を多量に用いた場合には界面活性剤に由来するべたつき感を生じやすいという欠点があり、高分子増粘剤を用いた場合には高分子増粘剤に由来する引っ掛かり感を生じやすいという欠点があった。 Conventionally, external preparations for skin such as creams and emulsions have been blended with various oils for the purpose of moisturizing the skin and changing the feel. Among them, silicone oil is widely used because it has a good sliding feel. And in order to mix | blend silicone oil stably, the technique of emulsifying using a surfactant in large quantities, or disperse | distributing using high molecular thickeners, such as a carboxy vinyl polymer, has been used. However, when a large amount of surfactant is used, there is a drawback that a sticky feeling derived from the surfactant is likely to occur. When a polymer thickener is used, a feeling of catching derived from the polymer thickener is felt. There was a drawback that it was likely to occur.
このため種々の検討が行われている。例えば特定のアルキル変性カルボキシビニルポリマーとシリコーン誘導体を組み合わせた毛髪用乳化組成物や皮膚化粧料、多価アルコールと低粘度シリコーン油とアルキル変性カルボキシビニルポリマーを組み合わせる化粧料、シリコーンポリマーとＡＭＰＳポリマーを含む組成物等が挙げられる。（特許文献１〜４参照） For this reason, various studies have been conducted. For example, emulsified compositions for hair combining a specific alkyl-modified carboxyvinyl polymer and a silicone derivative, skin cosmetics, cosmetics combining a polyhydric alcohol, a low-viscosity silicone oil and an alkyl-modified carboxyvinyl polymer, including a silicone polymer and an AMPS polymer Examples thereof include compositions. (See Patent Documents 1 to 4)
また、べたつきの少ない界面活性剤としてポリエーテル変性シリコーンを用いる検討も種々行われている。例えば、シリコーン油と特定の高分子量ポリエーテル変性シリコーンとを組み合わせる乳化化粧料、シリコーン油と特定のポリエーテル変性シリコーンを組み合わせるシリコーン乳化組成物等が挙げられる。（特許文献５、６参照） Various studies have also been conducted on using polyether-modified silicone as a less sticky surfactant. For example, an emulsified cosmetic combining silicone oil and a specific high molecular weight polyether-modified silicone, a silicone emulsion composition combining silicone oil and a specific polyether-modified silicone, and the like. (See Patent Documents 5 and 6)
更に、高分子増粘剤とポリエーテル変性シリコーンを組み合わせて、べたつきの低減と保存安定性の向上を図る検討も行われている。例えば、アルキル変性カルボキシビニルポリマーと特定ＨＬＢのポリエーテル変性シリコーンを組み合わせた皮膚外用剤や特定のポリエーテル変性シリコーンと油分と特定分子量の水溶性高分子を組み合わせる乳化組成物等が挙げられる。（特許文献７、８参照） Furthermore, studies are being made to reduce stickiness and improve storage stability by combining a polymer thickener and a polyether-modified silicone. For example, a skin external preparation that combines an alkyl-modified carboxyvinyl polymer and a polyether-modified silicone of a specific HLB, an emulsion composition that combines a specific polyether-modified silicone, an oil, and a water-soluble polymer having a specific molecular weight. (See Patent Documents 7 and 8)
これらの検討のごとく、皮膚に良好な感触を与え、べたつかず、且つ保存安定性に優れた皮膚外用剤が開発されているが、近年消費者の要求の高まりにより、更なる改良が望まれている。 As described above, skin external preparations have been developed that give the skin a good feel, are not sticky, and have excellent storage stability. However, in recent years, further improvement has been desired due to increasing consumer demand. Yes.
したがって、本発明の目的は、塗布時にのびが良く、べたつかず、皮膚にしっとりとした感触を与え、保存安定性に優れた皮膚外用剤を提供することにある。 Accordingly, an object of the present invention is to provide an external preparation for skin which has good spreading at the time of application, does not become sticky, gives a moist feel to the skin, and is excellent in storage stability.
本発明者等は、このような事情に鑑み鋭意検討した結果、アクリル酸ナトリウムとアクリロイルジメチルタウリンナトリウムとの共重合体である（アクリル酸ナトリウム／アクリロイルジメチルタウリン）コポリマーと、高重合シリコーンと、特定のポリエーテル変性シリコーンとを組み合わせて配合することにより、塗布時にのびが良く、べたつかず、皮膚にしっとりとした感触を与え、保存安定性に優れた皮膚外用剤が得られることを見出し、本発明を完成した。 As a result of intensive studies in view of such circumstances, the present inventors have determined that a copolymer (sodium acrylate / acryloyldimethyltaurine) that is a copolymer of sodium acrylate and sodium acryloyldimethyltaurine, a highly polymerized silicone, It has been found that by blending with a polyether-modified silicone, a topical skin preparation having good spreading at the time of application, non-stickiness, moist feeling on the skin, and excellent storage stability can be obtained. Was completed.
即ち本発明の請求項１は、（Ａ）（アクリル酸ナトリウム／アクリロイルジメチルタウリン）コポリマーと、（Ｂ）高重合シリコーンと、（Ｃ）下記一般式（１）
本発明は、塗布時にのびが良く、べたつかず、皮膚にしっとりとした感触を与え、保存安定性に優れた皮膚外用剤を提供するものである。 The present invention provides an external preparation for skin which has good spreading at the time of application, does not become sticky, gives a moist feel to the skin, and is excellent in storage stability.
以下、本発明の構成を詳述する。 Hereinafter, the configuration of the present invention will be described in detail.
本発明の皮膚外用剤に用いられる成分（Ａ）の（アクリル酸ナトリウム／アクリロイルジメチルタウリン）コポリマーは、Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｃｏｓｍｅｔｉｃ Ｉｎｇｒｅｄｉｅｎｔ Ｄｉｃｔｉｏｎａｒｙ［Ｔｅｎｔｈ Ｅｄｉｔｉｏｎ ２００４、Ｔｈｅ Ｃｏｓｍｅｔｉｃ，Ｔｏｉｌｅｔｒｙ，ａｎｄ Ｆｒａｇｒａｎｃｅ Ａｓｓｏｃｉａｔｉｏｎ発行］に「ＳＯＤＩＵＭ ＡＣＲＹＬＡＴＥ／ＡＣＲＹＬＯＹＬＤＩＭＥＴＨＹＬ ＴＡＵＲＡＴＥ ＣＯＰＯＬＹＭＥＲ」と記載される、アクリル酸ナトリウムとアクリロイルジメチルタウリンナトリウムとの共重合体である。該ポリマーを含む市販品としては、（アクリル酸ナトリウム／アクリロイルジメチルタウリン）コポリマー３７．５質量％含み、他の成分としてイソヘキサデカン、オレイン酸ソルビタン、ポリソルベート８０、及び水を含有する、ＳＩＭＵＬＧＥＬ ＥＧ（ＳＥＰＰＩＣ社製）があり、これを好適に使用することができる。 The component (A) (sodium acrylate / acryloyldimethyltaurine) copolymer used in the topical skin preparation of the present invention can be obtained from International Cosmetic Ingredient Diary [Tenth Edition 2004, The Cosmetic, Toiletry, and Fragrance United States It is a copolymer of sodium acrylate and sodium acryloyldimethyltaurine, which is described as “ACRYLOYLDIMETHYL TAURATE COPOLYMER”. As a commercial product containing the polymer, SIMULGEL EG (SEPPIC) containing 37.5% by mass of (sodium acrylate / acryloyldimethyltaurine) copolymer and containing isohexadecane, sorbitan oleate, polysorbate 80, and water as other components. Can be used suitably.
本発明の皮膚外用剤における、成分（Ａ）（アクリル酸ナトリウム／アクリロイルジメチルタウリン）コポリマーの好ましい配合量は、０．０３〜３．０質量％（以下、単に％と略す）であり、更に好ましくは０．１〜２．０％である。配合量が０．０３％未満であると保存安定性を損ねる傾向にあり、配合量が３．０％を超えるとべたつきを生じる傾向にある。 The preferred amount of component (A) (sodium acrylate / acryloyldimethyltaurine) copolymer in the external preparation for skin of the present invention is 0.03 to 3.0% by mass (hereinafter simply abbreviated as%), more preferably. Is 0.1 to 2.0%. If the blending amount is less than 0.03%, the storage stability tends to be impaired, and if the blending amount exceeds 3.0%, stickiness tends to occur.
本発明の皮膚外用剤に用いられる成分（Ｂ）の高重合シリコーンは、下記一般式（２）
その中でも、重合度として、ｎが２０００〜５０００であると仕上がりの滑らかさの面で特に好ましい。
The highly polymerized silicone of component (B) used in the external preparation for skin of the present invention has the following general formula (2)
Among them, the polymerization degree is particularly preferably n in the range of 2000 to 5000 in terms of smooth finish.
本発明の皮膚外用剤における成分（Ｂ）高重合シリコーンの好ましい配合量は、０．５〜１０．０％であり、更に好ましくは１．０〜５．０％である。配合量が０．５％未満であるとべたつきを生じる傾向にあり、配合量が１０．０％を超えると塗布時ののびが損なわれる傾向にある。 The preferred amount of component (B) highly polymerized silicone in the external preparation for skin of the present invention is 0.5 to 10.0%, more preferably 1.0 to 5.0%. If the blending amount is less than 0.5%, stickiness tends to occur, and if the blending amount exceeds 10.0%, the spread during application tends to be impaired.
本発明の皮膚外用剤に用いられる成分（Ｃ）ポリエーテル変性シリコーンは下記一般式（１）
本発明において、発明の効果を損なわない範囲であれば、上記必須成分の他に、アニオン性界面活性剤、両性界面活性剤、非イオン性界面活性剤、ガム質、油分、低級アルコール、多価アルコール、高級アルコール、粉体、噴射剤、防腐剤、キレート剤、酸化防止剤、ｐＨ調整剤、色素、香料等を配合することも可能である。 In the present invention, in addition to the above essential components, anionic surfactants, amphoteric surfactants, nonionic surfactants, gums, oils, lower alcohols, polyvalent alcohols, as long as the effects of the invention are not impaired. Alcohols, higher alcohols, powders, propellants, preservatives, chelating agents, antioxidants, pH adjusters, pigments, fragrances and the like can also be blended.
本発明の皮膚外用剤はクリーム、乳液等の皮膚化粧料、洗顔料、ハンドソープ、ボディシャンプー、メイク落とし等の皮膚洗浄料に応用することができる。 The external preparation for skin of the present invention can be applied to skin cosmetics such as creams and emulsions, skin cleansers such as facial cleansers, hand soaps, body shampoos and makeup removers.
以下に実施例、比較例を挙げて本発明を説明する。本発明は、これらにより限定されるものではない。 Hereinafter, the present invention will be described with reference to examples and comparative examples. The present invention is not limited to these.
実施例、比較例に示した物性試験、官能試験の試験方法は下記の通りである。尚、以下の表に示す組成物の配合量は、それぞれ％で示す。 Test methods for physical property tests and sensory tests shown in Examples and Comparative Examples are as follows. In addition, the compounding quantity of the composition shown in the following table | surfaces is each shown by%.
（１）のびの良さ、べたつきの無さ、しっとり感
２０名の被験者によって皮膚外用剤（クリーム）の試料を顔に塗布した。その後被験者本人が、のびの良さ、べたつきの無さ、しっとり感の項目について官能評価し、平均評価点を求めた。評価基準は、以下の通りである。
(1) Good spread, no stickiness, moist feeling A sample of a skin external preparation (cream) was applied to the face by 20 subjects. Thereafter, the subject himself performed sensory evaluations on items of good spread, no stickiness, and moist feeling, and obtained an average evaluation score. The evaluation criteria are as follows.
４：非常に良好
３：良好
２：やや悪い
１：悪い
4: Very good 3: Good 2: Slightly bad 1: Bad
（２）保存安定性
皮膚外用剤（クリーム）の試料を試験管に入れ、４０℃、３０００ｒｐｍの条件で３０分間及び１時間遠心分離機にかけた。その後の状態を観察し評価した。評価基準は以下の通りである。
(2) Storage stability A sample of the external preparation for skin (cream) was put in a test tube and centrifuged at 40 ° C. and 3000 rpm for 30 minutes and 1 hour. The subsequent state was observed and evaluated. The evaluation criteria are as follows.
○：１時間で変化なし
△：３０分で変化なし
×：分離、沈殿等変化あり
○: No change in 1 hour △: No change in 30 minutes ×: Change in separation, precipitation, etc.
実施例１〜３、比較例１〜５
表１に示した処方の皮膚外用剤（クリーム）を常法により作製し、前記各試験を実施した。その結果を表１に併せて示す。
Examples 1-3, Comparative Examples 1-5
A skin external preparation (cream) having the formulation shown in Table 1 was prepared by a conventional method, and the above tests were performed. The results are also shown in Table 1.
表１より明らかなように本発明の成分を用いた実施例の皮膚外用剤（クリーム）はいずれも優れた性能を有していた。一方、必須成分のいずれかを欠いた比較例では、のびの良さ、べたつきの無さ、しっとり感、保存安定性のいずれかの面で劣っていた。 As is apparent from Table 1, all of the external preparations for skin (creams) using the components of the present invention had excellent performance. On the other hand, in the comparative example lacking any of the essential components, it was inferior in any aspect of good spread, no stickiness, moist feeling, and storage stability.
実施例４（ハンドクリーム）
（Ａ）ＳＩＭＵＬＧＥＬ ＥＧ（商品名） ＳＥＰＰＩＣ社製 ２．５％
（Ｂ）高重合ジメチコノール（重合度３０００） ５．０
（Ｃ）ポリエーテル変性シリコーン ７．０
（ＢＹ１１−０３０（商品名） 東レ・ダウコーニング社製、５０％液）
グリセリン ５．０
メチルフェニルポリシロキサン ７．０
スクワラン ３．０
ジプロピレングリコール ５．０
キサンタンガム ０．０５
２−エチルヘキサン酸トリグリセリド ３．０
ビタミンＥ ０．０５
グリチルリチン酸ステアリル ０．１
クエン酸 適 量
クエン酸ナトリウム 適 量
混合植物抽出液 ０．５
（ファルコレックスＢＸ３２（商品名） 一丸ファルコス社製）
混合植物抽出液 ０．５
（ファルコレックスＢＸ５２（商品名） 一丸ファルコス社製）
香料 ０．３
精製水 残 量
Example 4 (hand cream)
(A) SIMULGEL EG (trade name) SEPPIC 2.5%
(B) Highly polymerized dimethiconol (degree of polymerization 3000) 5.0
(C) Polyether-modified silicone 7.0
(BY11-030 (trade name), manufactured by Toray Dow Corning, 50% solution)
Glycerin 5.0
Methylphenyl polysiloxane 7.0
Squalane 3.0
Dipropylene glycol 5.0
Xanthan gum 0.05
2-Ethylhexanoic acid triglyceride 3.0
Vitamin E 0.05
Stearyl glycyrrhizinate 0.1
Citric acid appropriate amount Sodium citrate appropriate amount Mixed plant extract 0.5
(Falco Rex BX32 (trade name) made by Ichimaru Falcos)
Mixed plant extract 0.5
(Falco Rex BX52 (trade name) made by Ichimaru Falcos)
Fragrance 0.3
Purified water balance
上記組成の皮膚外用剤を作成し評価したところ、のびの良さ、べたつきの無さ、滑らかさ、保存安定性について、優れた性能を有していた。 When the skin external preparation of the said composition was created and evaluated, it had the outstanding performance about the ease of spreading, non-stickiness, smoothness, and storage stability.
尚、上記の実施例４において使用した香料の組成を表２に示す。 Table 2 shows the composition of the fragrance used in Example 4 above.
Claims (3)
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| JP2525194B2 (en) * | 1986-09-02 | 1996-08-14 | 株式会社資生堂 | Skin cosmetics |
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| JP3580384B2 (en) * | 1995-03-31 | 2004-10-20 | 株式会社資生堂 | Emulsified cosmetic |
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| JP3644565B2 (en) * | 1996-11-12 | 2005-04-27 | ポーラ化成工業株式会社 | W / O emulsified cosmetic |
| JP2000034215A (en) * | 1998-07-17 | 2000-02-02 | Shiseido Co Ltd | Preparation for external use for skin |
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