JP4817182B2 - Hair cosmetics - Google Patents

Description

  The present invention relates to a hair cosmetic excellent in hair styling and conditioning effects.

The cosmetics and cosmetics industry related to hair is said to be a quarter of 500 billion yen out of 2 trillion yen in the overall cosmetic market. Technology development is progressing on a daily basis in relation to the field. In particular, the development of pharmaceuticals and natural / synthetic compounds in the fields of hair growth, hair growth, beauty and hair loss prevention is remarkable. Conventionally, Patent Documents 1 and 2 and the like respectively show techniques related to the use of unsaturated fatty acid esters of sterols or sterol sugar ester compounds in hair cosmetics.
Japanese Patent Laid-Open No. 2-6404 Japanese Patent Laid-Open No. 2005-170661

  Hair is always susceptible to damage, such as damage caused by drugs such as ultraviolet rays, permanents, hair dyes, bleach, etc., damage caused by heat from dryers, etc., loss of moisturizing ingredients by surfactants, etc., and damage caused by friction such as brushing. . Such damaged hair loses its elasticity, firmness and suppleness, and has the problem that it is hard to be styled or kissed, crumpled or broken. However, there are thoughts and needs for various hairdressing treatments as part of so-called fashion and fashion, and while knowing the above problems, temporary wave treatment by permanent wave method, set lotion, hair spray etc. Some people are satisfied with fashionable thinking through the treatments such as bleaching, hair coloring, and hair coloring.

  Shampoos and conditioners containing silicon derivatives, hydrolyzed proteins derived from keratin, silk, etc. are known for the purpose of improving the styling properties after washing the hair, but those that still have a sufficiently satisfactory effect are known. Did not exist.

  Therefore, the present invention gives good and gentleness to the hair, and in particular has excellent hair styling and conditioning effects for preventing damaged hairs (damaged hairs) from being tinged, rustled and broken. A fee is provided.

  Proteins such as keratin are the main components of hair, but it is thought that various trace components contribute to determining the integrity of hair such as suppleness, durability and glossiness. In particular, even if dead cells pile up and have a special structure, scientific research on how the hair that maintains suppleness, strength, etc. is supported has not progressed. is there. In such a situation, the present inventors devised an approach to solving the problem by reviewing components in hair, particularly lipidic trace components, and as a result, neutral hair such as cholesterol and its 1 / It has been found that there are trace amounts of polar lipids of 10 or less. The polar lipids can be separated by TLC or HPLC analysis, and by infrared analysis and MALDI-TOF mass spectrometry, lanosteryl-o-methoxyglucoside-14-methylpentadecanoate (Lanosteryl-o-methoxyglucoside-14-methyl- We obtained the knowledge that it is pentadecanoate.

  Cholesteryl glucoside and its esters, which are also plant or human, contribute to the stabilization of the membrane structure, and are thought to have a function of being synthesized according to the stress response of cells. In human hair, its physiological significance is not yet clear, but this lanosteryl-o-methoxyglucoside-14 is present in spite of the disappearance of phospholipids and the like present in the hair root in the hair shaft. -It was foreseen that the fact that methylpentadecanoate remained almost exclusively as a polar lipid would be important for hair to maintain its structure and quality.

  Furthermore, the present inventors have found that changes in hair quality / strength with age (Aging), drugs such as perms, hair dyes, bleaches, and similar changes seen in damaged hair caused by heat, friction, detergent cleaning, etc. As a result of intensive research and focusing on the relationship between the hair component, especially the possession of lipidic trace components, certain hair lipid components and compounds with similar structures are extremely important components for hair. By knowing that this can be done and treating the hair with these ingredients, it will give good and gentleness, and in particular, it will be possible to prevent damaging hair (damaged hair) from creaking, looseness and hair breakage. And ethylene glycol, diethylene glycol, triethylene glycol, polyethylene glycol, propylene glycol, dipropylene glycol, 2-amino-2-methyl -1,3-propanediol, 1,2-propanediol, 1,3-propanediol, polypropylene glycol, 1,3-butylene glycol, 1,2-butanediol, 1,3-butanediol, 1,4- Butanediol, isopentanediol, pentylene glycol, hexylene glycol, 1,2-pentanediol, 1,3-pentanediol, 1,4-pentanediol, 1,5-pentanediol, 1,2,3-pentanetriol 2,3,4-pentanetriol, 1,3,4-pentanetriol, 1,3,5-pentanetriol, 1,2-hexanediol, 1,3-hexanediol, 1,4-hexanediol, , 5-hexanediol, 1,6-hexanediol, 1,2,3-hexanetriol, 1,3,4-hexanetriol, 1,3,5-hexanetriol, 1,4,6-hexanetriol, 2-ethyl-1,3-hexanediol, glycerin, erythritol, pentaerythritol, dipentaerythritol, tray Thor, arabitol, xylitol, ribitol, galactitol, sorbitol, mannitol, lactitol, maltitol, inositol, panthenol, laminitol, valienamine, validamine, validatol, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, diethylene glycol monomethyl ether, diethylene glycol mono By combining a polyhydric alcohol selected from ethyl ether or a lower alkyl ester thereof, We found that it was possible to improve the effect of imparting suppleness and preventing blemishes, looseness and breakage against damaged hair (damaged hair), and improve hair styling, and completed the present invention. did.

：（一般式１）

：（一般式２）

：（一般式３）

：（一般式４）
［式中のＲ_１、Ｒ_３は炭素数６〜３０を有する直鎖状又は分枝状の飽和アルキル基又は不飽和アルキル基（アルケニル基）を示す。Ｒ_２は炭素数６〜３０を有する直鎖状又は分枝状の飽和アルキル基を示す。］ That is, lanosteryl-o-methylglucoside alkyl ester represented by general formula 1 (chemical formula 5), sitosterol alkyl ester represented by general formula 2 (chemical formula 6), sitosteryl glucoside represented by general formula 3 (chemical formula 7), general Hair cosmetics containing one or more sterol derivatives selected from among the sitosteryl glucoside alkyl esters represented by formula 4 (Chemical Formula 8), or further ethylene glycol, diethylene glycol, triethylene glycol, polyethylene glycol, propylene Glycol, dipropylene glycol, 2-amino-2-methyl-1,3-propanediol, 1,2-propanediol, 1,3-propanediol, polypropylene glycol, 1,3-butylene glycol, 1,2-butane Diol 1,3 Butanediol, 1,4-butanediol, isopentanediol, pentylene glycol, hexylene glycol, 1,2-pentanediol, 1,3-pentanediol, 1,4-pentanediol, 1,5-pentanediol, 1 , 2,3-pentanetriol, 2,3,4-pentanetriol, 1,3,4-pentanetriol, 1,3,5-pentanetriol, 1,2-hexanediol, 1,3-hexanediol, , 4-hexanediol, 1,5-hexanediol, 1,6-hexanediol, 1,2,3-hexanetriol, 1,3,4-hexanetriol, 1,3,5-hexanetriol, 1,4 , 6-hexanetriol, 2-ethyl-1,3-hexanediol, glycerin, erythritol, pe Taerythritol, dipentaerythritol, threitol, arabitol, xylitol, ribitol, galactitol, sorbitol, mannitol, lactitol, maltitol, inositol, panthenol, laminitol, varienamine, validamine, validitol, ethylene glycol monoethyl ether, ethylene glycol mono The present invention provides a hair cosmetic containing a polyhydric alcohol selected from butyl ether, diethylene glycol monomethyl ether and diethylene glycol monoethyl ether or a lower alkyl ester thereof.

: (General formula 1)

: (General formula 2)

: (General formula 3)

: (General formula 4)
[Wherein R ₁ and R ₃ represent a linear or branched saturated alkyl group or unsaturated alkyl group (alkenyl group) having 6 to 30 carbon atoms. R ₂ represents a linear or branched saturated alkyl group having 6 to 30 carbon atoms. ]

  The hair cosmetic composition of the present invention is excellent in hair styling effect and conditioning effect that imparts good and softness to the hair, and in particular prevents damaged hair (damaged hair) from being squeezed, loose, and broken.

In the present invention, the sterol derivative represented by the general formulas 1 to 4 is used. Examples of the “linear or branched saturated alkyl group having 6 to 30 carbon atoms” of R ₁ , R ₂ and R ₃ in the structural formula include, for example, 2-methylpentyl, 1-ethylbutyl, hexyl, isohexyl , Heptyl, octyl, nonyl, decyl, tetrahydrogeranyl, undecyl, dodecyl, tridecyl, tetradecyl, pentadecyl, hexadecyl, heptadecyl, octadecyl, nonadecyl, icosyl (eicosyl), heicosyl (heneicosyl), docosyl, tricosyl, pentacosyl, nanocosyl, etc. Particularly preferred are decyl, dodecyl, tetradecyl, pentadecyl, methylpentadecyl, hexadecyl, heptadecyl, octadecyl, nonadecyl and docosyl.

As the “linear or branched unsaturated alkyl group having 6 to 30 carbon atoms (alkenyl group)” of R ₁ and R ₃ in the structural formula, a straight chain having at least one or more double bonds. Or a branched alkenyl group having 6 to 30 carbon atoms, such as ethylbutenyl, methylpentenyl, ethylpentenyl, hexenyl, methylhexenyl, heptenyl, heptadienyl, octenyl, octadienyl, nonenyl, nonadienyl, decenyl, decadienyl, undecenyl, undecadienyl , Dodecenyl, dodecadienyl, tetradecenyl, tetradodecadienyl, pentadecenyl, pentadecadienyl, hexadecenyl, hexadecadienyl, heptadecenyl, heptadecadienyl, octadecenyl, octadecadienyl, nonadecenyl, nonadeca Examples include enyl, icosenyl (eicosenyl), henicosenyl (henecocenyl), dococenyl, docosadienyl, tricosenyl, tricosadienyl, hexacocenyl, heptacocenyl, octacocenyl, and the like, particularly preferably decenyl, dodecenyl, tetradecenyl, pentadecenyl, hexadecenyl, hexadecenyl, hexadecenyl, And enenyl, octadecenyl, nonadecenyl and dococenyl.

  As the sterol derivative used in the present invention, a pharmacologically acceptable complex salt can be used as well, and examples thereof include complex salts with inorganic bases and complex salts with organic bases. Specific examples of complex salts with inorganic bases include sodium salts, potassium salts, calcium salts, magnesium salts, barium salts, lithium salts, aluminum salts, copper salts, zinc salts, and iron salts. Examples of complex salts with organic bases include ammonium salt, trimethylamine salt, triethylamine salt, pyridine salt, picoline salt, ethanolamine salt, diethanolamine salt, triethanolamine salt, dichlorohexylamine salt, and dibenzylethylenediamine salt.

  Sterol derivatives used in the present invention include compounds synthesized by organic synthesis methods, as well as animals (mammalian hair (human, horse, sheep, rabbit, yak, etc.)), plants (rice bran, soybean seeds, yam, etc.), It can be freely selected from compounds extracted and purified from natural products such as microorganisms. Furthermore, compounds extracted and purified from natural raw materials can be used in the form of a crude extract containing a high content of sterol derivatives.

  As a method for producing lanosteryl-o-methylglucoside alkyl ester (LMG-AE) by organic synthesis, (1) lanosteryl-o in the presence of an alkali catalyst in an organic solvent such as dimethylformamide, dimethyl sulfoxide (DMSO), etc. -Method of reacting methyl glucoside (LMG) and alkyl ester (AE), (2) LMG is made into a molten mixture with fatty acid soap using water without using an organic solvent, and then AE is added in the presence of an alkali catalyst. (3) Furthermore, a so-called biomethod in which LMG and a fatty acid are directly reacted in the presence of a specific enzyme can be used.

  A typical method is (1) transesterification of LMG and AE in a solvent such as N, N-dimethylformamide, dimethyl sulfoxide (hereinafter abbreviated as DMSO) in the presence of an alkali catalyst. Obtainable. The LMG may be extracted and purified from natural products, and commercially available reagents and the like can be used.

Examples of AE include saturated or unsaturated fatty acids having 7 to 31 carbon atoms, preferably 11 to 22 carbon atoms (for example, caprylic acid (CH ₃ (CH ₂ ) ₆ COOH), capric acid (CH ₃ (CH ₂ ) ₈ COOH). ), Lauric acid (CH ₃ (CH ₂ ) ₁₀ COOH), myristic acid (CH ₃ (CH ₂ ) ₁₂ COOH), pentadecanoic acid (CH ₃ (CH ₂ ) ₁₃ COOH), palmitic acid (CH ₃ (CH ₂ )) ₁₄ COOH), iso-hexadecanoic acid (CH ₃ CH (CH ₃ ) (CH ₂ ) ₁₂ COOH), stearic acid (CH ₃ (CH ₂ ) ₁₆ COOH), behenic acid (CH ₃ (CH ₂ ) ₂₀ COOH), etc. Saturated fatty acids of: geranic acid (trans-Me ₂ C═CHCH ₂ CH ₂ CMe = CHCOOH), lauroleic acid (dodec-9-enoic acid), myristoleic acid (tetradec-9-enoic acid), palmitoleic acid (hexadeca- 9-enoic acid), petroceric acid (octadeca-6-enoic acid), elaidic acid (octadeca-9-enoic acid), linoleic acid (CH ₃ (CH ₂ ) ₄ CH = CHCH ₂ CH = CH (CH ₂ ) ₇ COOH), Shinoru acid (12-hydroxy octa dec-9-enoic acid), oleic acid _{(CH 3 (CH 2) 7} CH = CH (CH 2) 7 COOH), linolenic acid _{(CH 3 CH 2 CH = CHCH} 2 CH = CHCH ₂ CH = CH (CH ₂ ) ₇ COOH), erucic acid (CH ₃ (CH ₂ ) ₇ CH = CH (CH ₂ ) ₁₁ COOH), ricinoleic acid (CH ₃ (CH ₂ ) ₅ CH (OH) CH = CH (CH ₂ ) ₇ COOH), gadoleic acid (icosa-9-enoic acid), erucic acid (docosa-13-enoic acid, and other unsaturated fatty acids) and lower alcohols having 1 to 6 carbon atoms (for example, And esters with methanol, ethanol, propanol, butanol, etc.). Such AE may be used as a mixture of two or more. AE is usually used in an amount of 0.1 to 10 mol, preferably 0.2 to 5 mol, per 1 mol of LMG.

  As the reaction solvent, DMSO is used from the viewpoint of thermal stability, solubility in LMG, and safety. The usage-amount of a solvent is 20 to 200 weight% normally with respect to the total preparation amount of LMG and AE, Preferably it is 30 to 100 weight%.

  The alkali catalyst is present in a suspended state in the reaction system. For example, alkali metal hydrides, alkali metal hydroxides, alkali metal salts of weak acids and the like are effective, and alkali metal carbonates (for example, potassium carbonate and sodium carbonate) are particularly preferable.

  The reaction is usually carried out at 40 to 170 ° C, preferably 60 to 150 ° C. The reaction pressure is usually 0.2 to 43 KPa, preferably 0.7 to 32 KPa. In particular, the reaction is preferably carried out while distilling off the by-produced lower alcohol under the boiling conditions of DMSO. After completion of the reaction, the catalyst is neutralized with an acid.

  Usable acids include organic acids such as formic acid, acetic acid, propionic acid, oxalic acid, succinic acid, benzoic acid, citric acid, maleic acid, malic acid, tartaric acid and lactic acid. Of these, lactic acid and citric acid are preferred. When post-treatment such as extraction and distillation in the state where the alkali catalyst is active, the target product is decomposed and the yield decreases.

  The reaction mixture neutralized with the catalyst is then subjected to liquid-liquid extraction with an organic solvent and water, and is divided into an organic solvent phase containing LMG-AE and an aqueous phase containing unreacted LMG and DMSO. As the organic solvent, those which are hardly soluble in water and have a lower boiling point than DMSO are used. In particular, those azeotropic with water are preferred. Usually, alcohols or ketones having 4 or more carbon atoms such as n-butanol, iso-butanol, t-butanol, n-amyl alcohol, isoamyl alcohol, n-hexanol, cyclohexanol, methyl ethyl ketone, diethyl ketone, methyl isobutyl ketone are used. It is done. Preferably n-butanol or iso-butanol is used. The organic solvent is distilled off from the collected organic solvent solution to recover LMG-AE.

  As an organic synthesis method of sitosterol alkyl ester (S-AE), synthesis may be performed by a general esterification reaction method between sitosterol (S) and a saturated fatty acid having 6 to 30 carbon atoms, preferably 11 to 22 carbon atoms. it can. S may be extracted and purified from natural products, and commercially available reagents and the like can be used.

  The organic synthesis method of sitosteryl glucoside alkyl ester (SG-AE) is similar to the above-mentioned production method of LMG-AE, in the presence of an alkali catalyst in a solvent such as N, N-dimethylformamide and DMSO. It can be obtained by a transesterification reaction between (SG) and AE. SG may be extracted and purified from natural products, and commercially available reagents can be used.

  The dosage form of the hair cosmetic in the present invention is arbitrary, ampules, capsules, powders, granules, pastes, liquids, gels, emulsions, creams, ointments, mousses, powder dispersions, A dosage form such as a multilayer form or an aerosol form can be formed. Specifically, hair cream, hair lotion, hair oil, shampoo, rinse, hair treatment, hair spray, hair tonic, hair gel, hair essence, hair water, hair wax, hair foam, hair blow agent, blow styling lotion, hair restorer, Examples include hair nourishing agents, hair loss prevention agents, one-component hair dyes and two-component hair dyes, hair coloring agents such as hair colors, permanent wave one agent, two agents, hair straighteners, and hair bleach agents.

  The blending amount of the sterol derivative in the hair cosmetic composition according to the present invention is slightly different depending on the type and properties of the cosmetic form, the degree of expected action, and is not particularly limited, but is usually 0.00001 weight in the total amount of the hair cosmetic composition. The concentration is generally used in a concentration range of at least%, preferably 0.0001 to 20% by weight, particularly preferably 0.0002 to 10% by weight.

  On the other hand, in the present invention, in combination with the sterol derivative, ethylene glycol, diethylene glycol, triethylene glycol, polyethylene glycol, propylene glycol, dipropylene glycol, 2-amino-2-methyl-1,3-propanediol, 1, 2-propanediol, 1,3-propanediol, polypropylene glycol, 1,3-butylene glycol, 1,2-butanediol, 1,3-butanediol, 1,4-butanediol, isopentanediol, pentylene glycol, Hexylene glycol, 1,2-pentanediol, 1,3-pentanediol, 1,4-pentanediol, 1,5-pentanediol, 1,2,3-pentanetriol, 2,3,4-pentanetriol, 1,3,4-penta Triol, 1,3,5-pentanetriol, 1,2-hexanediol, 1,3-hexanediol, 1,4-hexanediol, 1,5-hexanediol, 1,6-hexanediol, 1,2, hexane 3-hexanetriol, 1,3,4-hexanetriol, 1,3,5-hexanetriol, 1,4,6-hexanetriol, 2-ethyl-1,3-hexanediol, glycerin, erythritol, pentaerythritol, Dipentaerythritol, threitol, arabitol, xylitol, ribitol, galactitol, sorbitol, mannitol, lactitol, maltitol, inositol, panthenol, laminitol, valienamine, validamine, validatol, ethylene glycol monoethyl ether, ethyl By using a polyhydric alcohol selected from polyglycol monobutyl ether, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether or a lower alkyl ester thereof, imparting suppleness to the hair, and damaging hair against damaged hair (damaged hair), It is possible to further improve the effect of preventing looseness and breakage, and to improve the styling property of the hair. Among these polyhydric alcohols or lower alkyl esters thereof, in particular, polyethylene glycol, propylene glycol, dipropylene glycol, polypropylene glycol, 1,3-butylene glycol, 1,2-pentanediol, 1,2-hexanediol, glycerin, 2-ethyl-1,3-hexanediol (octanediol) is preferred.

  These polyhydric alcohols or lower alkyl esters thereof are preferably in the range of usually 0.001 to 40% by weight (particularly 0.01 to 30% by weight) in the hair cosmetic composition of the present invention. If the blending amount is less than 0.001% by weight, the effect of the above combination may not be sufficiently exhibited. If the blending amount exceeds 30% by weight, for example, shampoo, rinse, etc. Except for this, after use, the hair feels sticky or stiff and may remain unfavorable from the standpoint of touch.

Furthermore, in the hair cosmetic composition of the present invention, if necessary, components usually incorporated in detergents, cosmetics, pharmaceuticals, quasi drugs, etc., such as alkyl sulfates, polyoxyethylene alkyl sulfates, α-olefins. Anionic surfactants such as alkyl sulfates, sulfosuccinic acid half alkyl esters, acylated glutamic acids, monoalkyl phosphoric acids and soaps; amphoteric surfactants such as amide amino acids and alkyl betaines; cationic surfactants such as alkyl quaternary ammonium salts Oils and fats such as silicon derivatives, ester oils and higher alcohols; water; humectants such as glycerin and propylene glycol; medicinal agents such as anti-inflammatory agents, anti-dandruff agents, bactericides and vitamins; preservatives such as parabens and urea; Thickeners such as perfluoropolyether and water-soluble polymers; such as oxybenzone External line absorbers; antioxidants such as dibutylhydroxytoluene and tocopherol acetate; colorants such as dyes and pigments; conditioning agents such as cationic polymers; pearling agents such as glycol esters; polymers for hair setting such as acrylic resin liquids; Various blended fragrances; other components listed in ENCYCLOPEDIA OF CONDITIONING RINSE INGREDIENTS (MICELLE PRESS 1987), etc., within a range not impairing the effects of the present invention, It can also mix | blend suitably.

In particular,
(1) Various fats and oils Avocado oil, almond oil, fennel oil, sesame oil, olive oil, orange oil, orange rafa oil, sesame oil, cacao oil, chamomile oil, carrot oil, cucumber oil, beef fat fatty acid, cucumber oil, safflower oil , Shea fat, liquid shea fat, soybean oil, camellia oil, corn oil, rapeseed oil, persic oil, castor oil, cottonseed oil, peanut oil, turtle oil, mink oil, egg yolk oil, palm oil, palm kernel oil, owl, palm Oil, beef tallow, pork tallow, squalene, squalane, pristane or hydrogenated products of these oils (hardened oil, etc.).

(2) Wax beeswax, carnauba wax, whale wax, lanolin, liquid lanolin, reduced lanolin, hard lanolin, candelilla wax, montan wax, shellac wax, rice wax and the like.

(3) Mineral oils Liquid paraffin, petrolatum, paraffin, ozokelide, ceresin, microcrystalline wax, etc.

(4) Fatty acids Lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, linoleic acid, linolenic acid, docosahexaenoic acid, eicosapentaenoic acid, 12-hydroxystearic acid, undecylenic acid, tall oil, lanolin fatty acid Synthetic fatty acids such as natural fatty acids such as isononanoic acid, caproic acid, 2-ethylbutanoic acid, isopentanoic acid, 2-methylpentanoic acid, 2-ethylhexanoic acid and isopentanoic acid.

(5) Alcohols Natural alcohols such as ethanol, isopropyl alcohol, lauryl alcohol, cetanol, stearyl alcohol, oleyl alcohol, lanolin alcohol, cholesterol, phytosterol, phenoxyethanol, etc., synthetic alcohols such as 2-hexyldecanol, isostearyl alcohol, 2-octyldodecanol, etc. .

(6) Esters isopropyl myristate, isopropyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, oleyl oleate, decyl oleate, octyldodecyl myristate, hexyl decyl dimethyloctanoate, cetyl lactate, myristyl lactate, Diethyl phthalate, dibutyl phthalate, lanolin acetate, ethylene glycol monostearate, propylene glycol monostearate, propylene glycol dioleate, and the like.

(7) Metal soaps Aluminum stearate, magnesium stearate, zinc stearate, calcium stearate, zinc palmitate, magnesium myristate, zinc laurate, zinc undecylenate and the like.

(8) gum, saccharide or water-soluble polymer compound gum arabic, benzoin rubber, dammar gum, guaiac oil, Irish moss, karaya gum, tragacanth gum, carob gum, quinseed, agar, casein, lactose, fructose, sucrose or ester thereof, Trehalose or derivatives thereof, dextrin, gelatin, pectin, starch, carrageenan, carboxymethyl chitin or chitosan, hydroxyalkyl (C2-C4) chitin or chitosan to which alkylene (C2-C4) oxide such as ethylene oxide is added, low molecular chitin Or chitosan, chitosan salt, sulfated chitin or chitosan, phosphorylated chitin or chitosan, alginic acid or salt thereof, hyaluronic acid or salt thereof, chondroitin sulfate or salt thereof, heparin, ethylcellulose, methylcellulose Polycarboxylate such as carboxymethyl cellulose, carboxyethyl cellulose, sodium carboxyethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, nitrocellulose, crystalline cellulose, polyvinyl alcohol, polyvinyl methyl ether, polyvinyl pyrrolidone, polyvinyl methacrylate, polyacrylate, polyethylene oxide and polypropylene oxide Alkylene oxide or its crosslinked polymer, carboxyvinyl polymer, polyethyleneimine and the like.

(9) Surfactant Anionic surfactant (alkyl carboxylate, alkyl sulfonate, alkyl sulfate ester salt, alkyl phosphate ester salt), cationic surfactant (alkyl amine salt, alkyl quaternary ammonium salt), amphoteric Surfactant: Carboxylic acid type amphoteric surfactant (amino type, betaine type), sulfate ester type amphoteric surfactant, sulfonic acid type amphoteric surfactant, phosphate ester type amphoteric surfactant, nonionic surfactant ( Ether type nonionic surfactant, ether ester type nonionic surfactant, ester type nonionic surfactant, block polymer type nonionic surfactant, nitrogen-containing type nonionic surfactant), other surfactants ( Natural surfactants, protein hydrolyzate derivatives, polymer surfactants, surfactants containing titanium and silicon, fluorocarbons Surfactants).

(10) Various vitamins Vitamin A group: retinol, retinal (vitamin A1), dehydroretinal (vitamin A2), carotene, lycopene (provitamin A), vitamin B group: thiamine hydrochloride, thiamine sulfate (vitamin B1), Riboflavin (vitamin B2), pyridoxine (vitamin B6), cyanocobalamin (vitamin B12), folic acid, nicotinic acids, pantothenic acids, biotins, choline, inositols, vitamin C group: vitamin C acid or derivatives thereof, vitamin D group: Ergocalciferol (vitamin D2), cholecalciferol (vitamin D3), dihydrotaxosterol, vitamin E group: vitamin E or derivatives thereof, ubiquinones, vitamin K group: phytonadione (vitamin K1), menaquinone (vitamin K2), me Dione (vitamin K3), menadiol (vitamin K4), other essential fatty acids (vitamin F), carnitine, ferulic acid, .gamma.-oryzanol, orotic acid, vitamin P such (rutin, eriocitrin, hesperidin), vitamin U and the like.

(11) Various amino acids Valine, leucine, isoleucine, threonine, methionine, phenylalanine, tryptophan, lysine, glycine, alanine, asparagine, glutamine, serine, cysteine, cystine, tyrosine, proline, hydroxyproline, aspartic acid, glutamic acid, hydroxylysine , Arginine, ornithine, histidine and the like, and their amino acid derivatives such as sulfate, phosphate, nitrate, citrate or pyrrolidone carboxylic acid.

(12) Various additives derived from plant or animal raw materials These are processed in a conventional manner according to the type and form of the product to be added (for example, grinding, milling, washing, hydrolysis, fermentation, purification) , Compression, extraction, fractionation, filtration, drying, pulverization, granulation, dissolution, sterilization, pH adjustment, deodorization, decolorization, etc., arbitrarily selected and combined), arbitrarily selected from various materials You can use it.

  The solvent used for extraction may be selected in consideration of the intended purpose and type of the product to be provided or the processing to be performed later. Usually, water, methanol, ethanol, propyl alcohol, isopropyl alcohol, butanol Selected from various organic solvents such as lower alcohols or water-containing lower alcohols such as isobutanol and pentanediol, polyhydric alcohols such as propylene glycol, 1,3-butylene glycol and glycerin or water-containing polyhydric alcohols, acetone and ethyl acetate It is desirable to use one kind or a mixture of two or more kinds. However, when it is not preferable to contain an organic solvent depending on the application, it is sufficient to use only water or ethanol that can be easily removed after extraction, and it may be used alone or in any mixture with water. The thing extracted and extracted may be sufficient.

  In addition, when using additives derived from plant or animal-based ingredients for systemic or topical external preparations and cosmetics, it protects skin and hair, moisturizes, improves touch and texture, imparts flexibility, and stimulates Relaxation, stress relief by fragrance, cell activation (cell aging prevention), suppression of inflammation, improvement of skin and hair quality, prevention of rough skin and its improvement, hair growth, hair growth, hair loss prevention, imparting gloss, cleansing effect, In addition to cosmetic effects such as fatigue relief, blood flow promotion, and warm bath effects, effects such as flavoring, deodorization, thickening, antiseptic, and buffering can also be expected.

Specific plants (herbal medicines) as raw materials include, for example, almonds (toen), ai (indigo leaves), aokazura (Keifu Fuji), Aoki (Aoki), Aogiri or Kenashia Ogiri (Ao Tung), Aotsu Samurai (wooden candy) , Aotenma, acacia, red ginseng, red spruce `` fruit '', red clover, red grapes, red ginseng (logwood), red wrinkles (red buds), red crested or red crested or reddish (root), red crested or reddish (ground yellow), Agi (Aki), Aki larch, Akinire (crusted skin), Aguay Guassou, Aguahe (Omiten coconut palm), Akebi (Kitsu), Asa (Asakojin), Maruba morning glory or morning glory (Chicken), Hydrangea (hydrangea), Ashitaba (Tomorrow), Azuki (Red Azuki), Asunaro, Acerola, Asenyaku (Asenyaku), Athira (Shokuyokanna), Anise, Abiyu, A Biurana, oilseed rape, Abemaki `` fruit '', avocado, ama, achacha (Amacha), Achacharu, Amadokoro (Jade bamboo), Amana (a light-hearted), amaranth (Hyuyu, Hagatetou, Himogeito, Senninkoku, Sugimorigateto, Hosoaogeito, Hasoagoito Aozulan, Amaranthus hypochondriacus), Amigasayuri or Baimo (shellfish mother), Aristolomeria (Yurizuisen), Arcana (Alcanna), Algarrobo (Cabe), Altea, Arnica, Alpinia or Katsumadai (Suzukuku), Aloe (蘆薈), Aloe vera, angelica, apricot or honanzu (Anzujin), Ansokkou (benzoic incense), yellow support, igakozolina (geo-biliary head), licorice or gecko licorice (indian oyster), rush (light heart grass), itadori (tiger cane root), yew (one Place), Strawberry, fig (no flower `` fruit, leaf ''), Ichihatsu (first), Ichibi (winter lion), Ichiyakusou (one medicinal herb), ginkgo (Ginkgo `` seed, leaves ''), Japanese yellow peas (distant), carob, Japanese beetle ( Taillexi), Inubiyu (Honagainubiyu), Rice `` Seeds, Seed coat '', Inondo `` Seeds '', Ibuki-so-sou, Nettle, Ylang-ylang, Iwa-tobacco (Iwabuchi), Iwahiba or Iwamatsu (rolling mushroom), kidney beans, oolong tea, fennel (mustard) , Wheat (Chibusanoki), Ukiyara (Sanryo), Uguisukagura `` Fruit '', Himewikyo, Turmeric (Urban), Duckweed, Usubasaishin or Keirinsaishin or Oshusaishin (spicy), Usvenia Oy, Usbeni Hollyhock, phalaenopsis, weevil (summer hay), udo or shishiudo (gung, alone, tangy), unyadegato (unkari) A, Cat's Claw), Uba tea, Ume (Japanese apricot `` seed, pulp ''), Japanese white beetle, Uwaurushi (Kusako-kemomo), Unshuumika (Chen), Unboku, Estragon, Ezoukogi (Tomogoka), Ezo-suzuran, Echinashi (Hosobamurasaki Barengiku) , Enishida, Enokitake (榎 茸), Ebisugusa or Cassia Tora (Keiko), El Campre, Elderberry “fruit”, Elemi, Elingi or Pre-Lotus Elinji, Enju (Safflower, Camellia rice), Pea, Ogi or Kibanaogi (Yellow Twilight), Naruko Yuri or Kagura-mabanaru Koyuri (Yellow), Ohisasa Yuki or Sasano Yuki, Ouren (Yo Ren), Ogata Houken, Okarasuri (Karokon), Oguruma (Civil Works Incense), Otsu Samurai (Prevention), Psyllium , Car forage), toucan thistle (Zhengzhou leakage, bald eagle), toucan Mi (coconut palm), toucan cactus, Ovana okera or okera (white moth), Osana squirrel (Banaba), Ooyabaya shabushi "fruit", Ohitake, Tosushi (cereal essence), Omia catechu, Oha hawthorn or Hawthorn Barley (barley), Oka, Okazeri (snake bed), Okra `` fruit '', Oguruma (overturned), Oguri higotai (Zhengzhou leakage, indigo head), Panax ginseng or Tochibaninjin (carrot), Hypericum pertussis Hypericum pertussis (brother cut grass), Odrichospodium (continuous), Onamomi (amberjack), Onigurumi, Onidokoro or Tokoro or Nagadokoro (hikai), Onyogara (Tempa), Onyuri or Sasayuri or Hakatayuri (lily), Onoelan, Ononis (Kibaba), Ominae (defeated soy sauce), Yuuko, Dutch mustard (Lesson), Dutch jellies, Dutch ville, Dutch honey bees, olives `` fruits, seeds, leaves '', oregano, orange `` fruits, pericarps '', silkworms (ripening yellow), cacao `` fruits, pericarps, seeds '', oysters (柿蒂 `` `` Leaf ''), Kagikazura (Katsufuji 鈎), Kakidooshi or Kantori (Lotus herb), oysters, Gaku hydrangea, Cassia, casino oyster (fruit `` fruit ''), gadget (莪 朮), oak (kaki tree, 槲 葉), Cascarilla, Cascaraca grada, Gypsophila, Kasensou, Crab (Kinshato), Kaniwa, Carnation, Cyprus (Valentine Root), Hippopotamus, Hippopotamus, Birch or Fern birch (Bird), Gerbera, Pumpkin, Kapokoki (Seeds), Kahoku salamander蜀椒), cattail (yellow-yellow), chamomile or Roman chamomile, chamomile (weed), cam cam (camo duck), carraguwa or yamagwa (mulberry moth), camo Rara, Carax salmon man, Crows cricket or Cinnamon cucumber (Wang 瓜), Crow Bishaku (Half summer), Oats, Guarana `` seed '', Calahoo (Koh-Pak), Karaya, Garyu, Karin (Kiso), Garcinia, Kawamidori, Kawara psycho ), Kawajisha, Kawaratake, Kawaranadeshiko (stone bamboo) or Ezokawaranadeshiko (buckwheat, buckwheat), Chinese carrot (blue potato), Chinese mugwort (bamboo chin), Kansui (Akansai), Licorice (licorice), Kantarasa , Candelilla, canto, canna, kanran, raspberry (Ezo strawberry, Dutch strawberry, shrimp strawberry, nava white strawberry, maple strawberry, European raspberry), kiwi `` fruit, leaf '', kikarasuri (guro-root), kyo-kyo (kikyo, bellflower root), chrysanthemum (Chrysanthemum flower, Shimakangi, Korean ginkgo), Kikutaniku, Kisage (fruit), Gigi ( (Shoe), pheasant (fruit), kizuta, yellow aloe vera, yellowfin mint, quina, linden (shinkona, red linden), quinoa (quinoa), yellowfin (yellow tuna), yellow bean, kimnema sylvesta, yellowtail, cabbage, cabbage `` unripe fruit '', Caraway, cucumber, gyory (Nishikawa willow, taiyanagi), Kiraja saponaria, Kiraya, Kiranso (golden grass small grass), kumquat `` fruit '', kinkiju, ginsekai, kimbusen, betel, kinzhiki (Sentsukakusa), kinlan, gin orchid, Goldfish, guapeba vermela, guava `` fruit '', guayule, quellus infectria (garlic), kukui nuts, kugenumaran, wolfberry (bamboo shoots, coconut leaves, cocoon leaves, ground bark), kusasugikazura (tenmon winter), kuzu (kudzu) , Camphor, gooseberry `` fruit '', carrot carrot (yellow flower bud), Titi River, Gardenia (Mountain Reed), Kunugi (Ezo Sou), Kupuas, Kubeba, Kumazasa, Kumatsutsura (Horse Citrus), Clara (Bitter), Cranberry "Fruit", Chestnut "Seeds, Fruits, Astringent Skin", Curkurigo Latifolia " `` Fruit '', grapefruit `` fruit / leaves '', buckthorn, black scabbard (rescue), tortoise kokoshi or kurobanahiokikoshi or tokikoshi (prolongation grass), cloves (clove, clove), gumbai tuna (sekimei, blossom) ), Celosia (chicken flower, chicken crown), gekkavidin, bay bay (bay laurel), Kenashi Sartorii rose (Tsumago, mountain return), Gentiana, Gennoshouko (Oldgrass), Kemponashi (Kigushi), Kokisekoku, Kushimikan (Koji, Tachibana) , Giant mandarin orange, buckle mandarin, sagamikoji, ponkan, santara (Tachibana bark)), Koshinbara (moon flower), Kousuihakka, Kozo `` fruit '', Kocha (tea), Kohone (river bone), Kohon (Kashimoto, Karatsumoto), Koryang, Koryokyo (Koryo), Koendoro `` Fruits '', Kourien (Huo Ren), Koganebana (Yellow Gon), Cowberry (Etsutachibana), Coco `` Fruits '', Goshuyu (Kureo), Gosho Strawberry (Golden Bonsai), Pepper (Pepper), Cosmos, Copaiba Balsam, Coffee `` `` Seeds, leaves '', kofukisarokoshikake (plum infestation), kobushi or magnolia (hot pepper), burdock (beef bowl, beef eggplant), burdock leopard, sesame (sesame), sesame seedling (genus ginseng), garbage (serum quail), sakanekazura, binankazura or pine bush , Wheat (wheat), rice or rice bran “red cocoon, white birch”, rice oil, cola acminata “seed”, cola bella “seed”, coleus forskori, colony llya, koroha `` Fruit '', Colombo, Konzurango, Kombu, Konjac, Comfrey (Chang Zhang grass), Sisal (Sisal Asa), Sai Hailan, Sakaneran (Ezosa Kaneran), Saximas button eel or cinnabar bud or cinnamon ginseng (wei Sensen), Sakura (Oshima cherry, Yamazakura, Oyama cherry, Edhigashi, Bean cherry, Miyaza cherry, Yoshino cherry, Takane cherry, Kasumi cherry, Kohigan, Sato cherry, Kanzakura `` Leaf, flowers, fruit, bark (cherry bark) ''), cherry, pomegranate, Sasa, Sasabaginran, Sasanka, Sasiomodaka , Sweet potato, sugar cane, sugar beet, sunflower jujube (acid vine), saffron (bancho flower, west red flower), sapodilla, sapotea mariyo, pomelo `` fruit '', scorpion, salmon berry `` fruit '', salamander ginger (sara), sarancito U (sand indigo sashimi), Salvia (sage), Sagaki Kyo (mountain vegetables), Sawagurumi (Yamatoko), Sangaku cactus, Sangre de Grado (croton), Sangikuyosou, Sanshichininjin (Ginseng), Sanshuyu ( Yam), salamander (sanroku), sanzukon (yamazune), shia (carite), cyanoki `` fruit '', shiitake (shiitake), shion (purple), winged bean, jikitarisu, shikunshi (mikoshi), perilla or blue-green Chiri-manji or Katamen-jiso (Shiso leaf, Shiso-ko), Rosewood, Linden, Chinese horned berries, Chinese white-headed shrimp (Food), Shimeji (Hinshimeji, Shakashimeji, Hatake-shimeji, Oshiroi-shimeji, Buna-shimeji, Honjimeshi, Shirotamogitake) , Peony (glaze), shajin (shasan), jasmine (mackerel), janohi (barley winter), ju Black-headed bean, Black-headed Knotweed, Shukusha-mitsu (Sandhi, Shredded sand), Juzudama, Shuro `` Fruit '', Shunran, Jiao-souyashi, Ginger (Ginger), Gyozan Hydrangea (Tsunzan), Shobu (Tsubaki, Sone), Shozuk `` Fruit '', Shirakashi `` Seeds '', Silane (Bikkyu), White Rooster butterfly `` Seeds '', White clover (Clover), White clover (chicken bone grass), White squirrels (Nioiris), Shirobanatsuta `` Flowers '', Shirobanarupin, Shirominanten (Southern fruit), Cinchona Sacylbra, Ginkgo biloba (Mizuka, Mika, Shencho), Cinnamon, Cinnamomum cassia (Cinnamon), Watermelon (Sairan), Honeysuckle (Gin silver flower, Shinobi), Sorrel (Acid), Swimberry "fruit", Star apple , Stevia, Strawberry “Fruit”, Suzu-Psycho (Xucho), Sugina (Question), Suburihi (Horse dents, horse dents), plums `` fruit '', sulgaran (oran), Japanese red pine `` cone '', Japanese larch, Japanese cypress, Japanese walnuts, hawthorn, Japanese cypress, Japanese dandelion, Japanese horse chestnut (Maronier) , Pear `` fruit '', sunflower, elder, horseshoe (juniper, pine), yarrow (milfoil), rose, larva, mistletoe, mint mint, or horseradish, horseradish, Sekisho (Ishizone), Sekkoku (Sakura Sekkoku, Koki Sekkokoku, Obanase Sekkoku, Okinawa Sekkokoku, Hon Sekkokoku, Kocho Sekkok, Shika Sekkokuk, Kibana Sekkok) (Dendrobium, Shiso), Cedron (Boshu) ), Mallow, sage, celery, nematode (river cucumber), sensinren (centripetal ream), sendan, sennin cactus, senna `` fruit, leaf '', sennin (Daisen), senburi (this drug), Senboku, Soka (grass), Elephant burrow, Sobain baibai, buckwheat `` seed '', Somer potato, broad bean, Daio (daihuang), Japanese radish, soybean, Daidai (orange peel, strawberry), Takasagorihigotai (Southeast indigo sashimi), Takasaburo (旱 lotus grass, Takatodai (Daikan), Takarabi (ビ 狗), dark sweet cherry `` fruit '', hollyhock, hollyhock (thyme, perilla), tachidokoro (hikai), tachiyanagi, tamarind `` seed '', onion, beetle ( Pepper), taranoki `` fruit, leaves, root bark '', tarayou (large leaf winter blue, Ichiha tea, bitter tea, bitter tea), dahlia (tenjiku button), taru , Tanquilima, tanshichiwa, tanjin (dansang), dandelion (bamboo pudding) or shirobana dandelion or mouko dandelion, danmaru, cherry `` fruit '', chigaya `` fruit, root, bud '', chiketsujinjin (bamboo ginseng), chicory, chancapiedra ( (Kantachi Kumiso), tulips, chocolate staghorn, artichokes (artichoke), ginseng (large yellow), ginseng (mushrooms), ginkgo biloba (mushrooms), choreimaitake (mushrooms), chorogi, tsukimisakaneran, tsukuritake (Mushrooms), camellia, camellia, camellia, clover (lacquered cocoon grass), camellia (duck cocoon grass), tsurumazuki (red azuki beans), tsurutsuchiakebi, tsurudukudami (what neck rice cake), tsuruna (apricot apricot), tsuruminjin (four leaf ginseng), tsurumame , Camellia, deco, walnut, duberry 'fruit , Tengusa, Tencha (bamboo tea), Tendai Yaku (glaze), Touga (winter lion), Toka Kazura, Capsicum (Banban), Touki (Return), Tokinsenka (Marigold), Tousakachi, Tounabena (river cut), Corn or corn hair (southern cocoon hair), Japanese horned potato (Sadako), Torindo or Ginseng (Dragon gall), Tokusa (wood band), Dokudami (10 medicines), Tokon (napping roots), Toshishi or Mamedaoshi or Neshikazura, Tochu ( Tochu (bark, leaves, root)), ash (crust), tomato, tragacanth, triacanthus (seed), truffles (carrot), Turkish turkey, tormentilla, dronoki, toro-aoi, tongamame, nigerian berry `` fruit '', Chinese yam Or Yam (Yakuyaku), Nagi Ikada (Butcher Bloom), Naginata Koju, Nazuna, Rapeseed Solid bean or vertical bean (sword bean), Natsumikan, jujube (Otsuchi), Naniwaibara (Golden cherry), Nabena (continuous), Nameko, peanut (peanut), Nanten (Southern fruit), Nanban karamushi (Sanma), Niois violet, Nigaki (bitter tree), sagebrush (bitter melon), nutmeg, Kay or Nikkei or Ceylon Nikkei or Yab Nikkei (Kinshie) or Keishi (Katsura branch), nymph plover, leek (lion), elderberry (bone, `` fruit, flower, stem ``, Leaves ''), garlic (large coral), nurde (penta), leek, nemno or nebu or nebi or nemlinoki or digokubana (community), noamis (large cormorant), neubara (fruit), nousenkazura (Lyoen flower), nogateto, yarrow, Nodake (frontal cucumber), wild rose, peach, pineapple `` fruit '', hibiscus (bushouge, furinbusouge, roselle), hailindou, hauchiwa, pau do Hose, Hakamauraboshi (bone crush), Hakukayumatou, Hakusanchidori, Hakusen (white tine), Hakuruberry `` fruit '', Hakobe (breeding), hazelnut (coconut), Hashiridokoro (roth root), basil, lotus (lotus, lotus) (Meat, lotus), parsley (Netherlands jelly), hadakamugi, batata, wasp or madake (bamboo shoots), patchouli, mint (thin load, thin load leaf), peppercorn, pearl barley (yokuinin), hanasuge (knowing mother), banana, hana mint, Hanabishi (Shitsuri, Shitsutsuri), Vanilla Bins, Papaya, Hakogusa (Paso), Pahalobobo, Hub `` Whole Grass, Stem, Leaf '', Paprika, Hamakakiran, Hamago or Mitsuba Hamago (Vulgaris), Hamasuge (Incense), Shrimp (Shitsu), Hermanus (Maikai), Hamabou Fu (beach windbreak), Hamamelis, Palm, Rose (Rose), Balata, Balata rubber, Agaric Bamboo, White-faced agaric, Ukimori no-kasa), Haran, Pariurus (Prunus vulgaris), Parietalia, Harkanran, Balsamina (Turureishi, Nigari), Harnile (Crustacea, White skin, Bamboo leaf), Barbasco, Harlindou, Handaikai ), Breadfruit, giant eagle (dried), chickweed carrot (participant), pecan nuts, ganbanana (stone wall, vine rosacea), hygurumadaria, higotai, shinki (rhizomi), pistachio, beet, human camellia (stone wall), Hitosumenishi, Daisies (Daisy), Hinata Taikozuchi (cow knee), chickpeas, Hinoki, Hiba, Castor, Sunflower, Peppers, Himeuzu (Tempo), Himematsu (Kaori), Himematsutake (Kawariharatake, Hiromatsutake), Himetakeran "Fruit", beakshi, beakkyu, hiyu "fruit", chickpea, hi Lame, Bellows, Hyacinth clover (bald eagle), loquat `` fruit, leaves, stems '', betel wax (large clothes, coconut), puer tea, sweet peas (south rattan), fuki, fukidan popo (clover winter flower, clover winter leaf), Fujibacama (Orchid), Fuji Bean (Tsuname), Fujimodoki (Chrysanthemum salmon, Camellia), Grapes `` Fruits, pericarps, seeds, leaves '', Beech, Fuyumushinakusatake (Cycium cordyceps), Brazilian licorice, Brazilian carrot, Brazilian palm, Brazilian elephant Black Palm, Blackcurrant `` Fruit '', Blackberry, Branjen, Plum `` Fruit '', Fruceraria, Blueberry (Prunus japonica), Prunes, Floral Blanca, Blonde Psyllium, Bundow (Mung Bean), Hazelnut, Loofah, Hetsukaran, Safflower ( Safflower), Henken, Belladonna, Berry "fruit", Persea, Pervian Berg, Pereschia grandifolia, red beetle or Ixusa (scenic sky), Boysenberry `` fruit '', Bakigi or Niwaxa or Nendo or Hahagaki Kokia (silk), Hausairan, Dendrobium (Daffodil, Acute pupa, Periosteus), Powteria sapota, Powteria rukuma, spinach, spinach, physalis (Torune), honoki (Japanese folk magnolia, pak), bokeh (wooden moss), hosoba aragiku (bitter moth), hosobaoguruma, hosobanaokera (蒼朮), Kageten 37), Hosobabarengiku, Bodaiju (bamboo tree), buttons (peony `` flowers, leaves, stems, bark ''), button pi (peony skin), hops, jojoba, borage (Lulichisha), Bordeaux, white berry `` fruit ”, Hononiku (meat jugo, Daige), Honsecek (iron skin stone, sparrow mountain stone wall), Mizul Tennan Show (Tennan star), Mai Ke (Maiko), Maou (mao), Maca, Macadamia nut, Margaret (Mokushungiku), Macri (Marine grass), Magwa (mulberry white bark `` bark, leaf ''), Magnolia sprenger, Masalan saba, Masalan suba de Seara, Masheira de Boi, Mashua (Tamanozen Hallen, Kyukonkinrenka), Matatabi (Tenten-don), Matsukasa, Pine “Leaf, Bark, Root”, Matta Oryo, Matsutake (matsutake), Matsuhodo (茯苓) , Matico (Cordon Schijo), Mayoram (Hanahakka), Malvano Jazine (Bitter), Mulberry `` Fruit '', Quince, Malene (Bilaud Muzuka), Mango, Mangosteen, Manzanya (Andesca Mitsule), Manshugurumi, Mandarin `` Fruit '', Mannentake (Ganoderma lucidum), pheasant (fruit berries), Mishima Saiko (Shibako), Mizuohobako or Mizu Sagao (Dongweed), Mizokakushi (half-sided lotus), Misohagi (Chikuma), Mitsugaya or Niwayanagi (Henshu), Mitsugashi, Mitsuba, Midori Zapote, Midorihakka, Mimosa, Myouga, Miracle Fruit "Fruits", Myrrh, Milobaran , Wheat straw, mugweed, mugwort, mugwort (prolonged skin), munya, murasaki (purple root), murasakiki kibu or omura sakikibu (purple pearl), murasaki corn, murasaki kinafuji (Kunming chicken blood wisteria), megakansa opuntica, mesima cob (Mulberry yellow), Mejijiki (beneficial mother grass), Mebougi, Japanese primrose (Evening primrose), Melaleuca, Melissa, Merirot, Melon `` Fruit '', Moukomugigi, Mosouchiku, Mokukirin, Mogi (Pepper), Mochinoki, Mokko (wooden incense), Momijiba Daio, peach (peach "leaves, seeds, flowers, fruit"), coconut, morelloche Lee `` Fruit '', Morohaya (Hemp), Yakawa Murasaki Imo, Yakuchi (Masatoshi), Yakuyo Garega, Yagurumaso (Yagurumaiku), Cornflower, Yacon, Yaba Santa, Yachabushi (Yagari) or Himeya Shabushi or Obayaya Shabushi '', Willow willow, starfish (octagonal gold plate), mistletoe (willow parasitism), willow (kawa willow, holly willow, weeping willow, red willow, cat willow, incolyana, kinu willow, koryanagi, unryu willow, palm, willow, willow (Village willow, Dronoki), Willow tree `` leaves, stems '', Yaba Santa, Yabugarashi, Yabukouji (purple gold beef), Yabu tobacco (Tsuruga, Tenmeisei), pokeweed (commercial land), Yamadoritake (Bortini, Cep, Steinpilz), Yamahannoki (榛), bayberry, sagebrush, eucalyptus, yukinoshita (tiger ear grass), yucca or flavifolia, yuzu `` fruit '', lily, sagebrush, mugwort (lily leaf), ligan (thunder circle), lime `` fruit '', rye , Lacanca `` fruit '', raspberry `` leaves, fruit '', latania (chlamelia), lacquer or shallot (palm white), lavender, longan (long-eyed meat), agave (Aonu agave, fuchlin agave), ryocha (green tea), apple `` fruit, `` Seeds, leaves, roots '', gentian, lubas or suabisimus (so cool), rulitama thisami (cold beetle, cinnamon sashimi), litchi (toothpick, toothpick core), lettuce (chisha), red currant `` fruit '', red pitaya , Lemon "fruit", lemongrass, forsythia or Chinese forsythia (ream), forsythia, wintersweet Rouyashi, Lokon (Yoshi, Ashine), loganberry "fruit", rosemary (Rosmarinus officinalis), rose hip (Novara), wasabi, Watafujiutsugi (dense Komuhana), burnet (Chinire), and the like.

  As seaweeds, seaweed [Green algae: Chlorella vulgaris, Chlorella pyrenoidosa, Chlorella ellipsoidia, Aonori (Usba aonori, Sugiaonori, Hiraaoori, Boaonori, Hosoeda Aonori), Anaaoosa (Aosa)] (Macombu, Resilibu, Hosocome, Mitsuishi Kombu), Wakame, Hirome, Aowakame, Giant Kelp (Macrocystis Integrifolia, Neocitus Ruetkeana), Hijiki, Hibamata, Umiuchiwa, Usubaumiuchiwa Umiuchiwa, Akaba Umiuchiwa, Konami Uchiwa, Okinawa Uchiwa, Usuki Uchiwa, Etsumi Uchiwa], seaweed [Red algae: Hijirimen, Maca (Tengusa), Hiraksa, Syria, Oaxa Caterpillar, Yatabegusa, Yuukiri, Shimatengusa, Tosakanori, Togekirinsai, Amakusakirinsai, Giraffe, Juniper ginkgo rhinoceros, Tsunomata, Totsuka (Yahazutsu notamata), Ezotsunotamata, Togetu no Takita , Yaleus banori, Kagius banori, Susius banori, Haius banori, Akamo mizunori] and the like.

  In addition, other algae such as green algae (Chlamydomonas: Chlamydomonas, Akayukimo, Dunaliella: Dunaliella, Chlorococcus: Chlorococcus, Anemone: Quanomomo, Volbox: Ougenmawari, Volbox, Palmera, Yotsumeo, Aomido: Chrysanthemum, Aoumidro, Tirguimidro, Hibidoro: Hibidoro, Aosa: Anaaaosa, Amiaosa, Nagaaosa, Kawanori: Kawanori, Friccella, Shiogusa Magama genus: Magamata, Iwagata: Fusaikawa, Surichogata, Heraiwata, Kurokita, Hanemo, Genus: Mill, Chromel, Sakibutimil, Nagamil, Hira Lemon, Casanori genus: Casanori, Jusmo genus: Jujusmo, Tamajusmo, Mizojuzumo, Mika ヅ kimo, Korekaete, Tsutsumimo genus: Kyukougusa, Hitogususa genus: Humanegusa, Hirohatohigususa, Umushihimoe, Sakikimoe Sumiremo: Sumiremo, Hoshimamidro, Fushinashimidoro etc.).

  Cyanobacteria (Suizenjinori: Suizinori, Aoko, Nenju: Kawatake, Ishijelly, Hassai, Yuremo, Rasenmo (Spirulina): Spirulina, Trichodesmium (Iaciasio), etc.

  Brown alga Sanadagusa: Sanadagusa, Fukurimamiji, Commongusa: Commongusa, Yahazugusa: Ezoyahaz, Yahazugusa, Uraboshiyahaz, Jigamusa: Jigmygusa, Umichiwagusa, Umamisakugakua, Hakusou : Navarimo, Chasomen genus: Motsuki Chasomen, Matsumo genus: Matsumo, Nagamatsumo genus: Nagamatsumo, Okinawa mozuku: Okinawa mozuku, fake Tomozuku: Niseft Mozuku, Futomozuku: Futomozuku, Ishimozuku: Ishimozuku, Kuromo: Kuromo, Nisemozuku: Nisemozuku, Mozuku: Mozuku, Ishige: Ishige, Iroro, Ichimegasa: Ichimegasa Umibosu, Urushigusu: Urushigusa, Keurushigusa, Tobaccogusa, Composita: Composita, Haberodomo: Haberodoki, Havanori: Habanori, Habanori: Habanori, Commonbukuro, Ezobukuro, Ezobukuro Chishima fukuronori genus: Chishima fukuronori, Kagomenori genus: Kagomenori, Muraridori genus: Murachidori, shark genus: shark zusa, genus genus: lobster, genus genus: yokojimamanori, Ganoderma genus: cynomolgus, fennel spider: fennel spider, vine genus: turmo, turtle genus: sea turtle, scorpion genus: sujime, misji kumbu genus: misji kumbu, atsuba misji kumbu, kumbu genus: tsutsugara kumbu, oyster kumbu, onikombu, gakonbubu Barracuda, Trollocombu: Trollocombu, Antokume: Antokume, Kajime: Kajime, Tsuruarame, Kurome, Kikuishikombu: Kikuishicombu, Nejikcombu: Nejicombu, Kuroshiome: Kuroshiome, Nekoshikonbu, Aramei Genus: Ainuwakame, Chigaiso, Oniwakame Ezoi Shige: Ezoi Shige, Yabane Moku: Yabane Moku, Rappa Moku: Rappa Moku, Joromoku: Ugano Moku, Jo Lomoku, Hiemoku, Honda Walla: Tamanashimoku, Isomoku, Nagashimamoku, Akamoku, Shidamoku, Honda Walla, Nejimoku, Narasamo, Mametawala, Tatsukuri, Yatsumata Moku, Umitora no Moku, Fushishimoku, Mohmokumoku, Hahamokumoku , Ukimo: Ouokimo, Burukimo: Burukimo, Kayamonori: Kayamonori, etc.).

Red algae Genus: Sea urchins, Tsukumonori, Anemone crickets, Astragalus, Amaranthus, Amaranthus, Agaricata Genus: Tamaitadaki, Kaikekenori Genus: Kaginori, Kaikekenori, Tengusa: Himetengususa, Hytengususa, Oobusa, Nambugu , Kohira, Yohira, Kinukusa, Hibirodo: Hibirodo, Himebiro, Isomumedo: Isommedo, Aedes: Rhizome, Ryumons: Ryumon, Ranunculaceae, Nisekare Naminohana: Hosobanaminohana, Naminohana, Sangomodoki: Ragaramomodoki, Shiogusagoromo: Shiogusagoromo, Iwanokawa: Etsukiiwanawa, Kinokawa: Kinokawa, Kanonote, Sangori Kyono Shiro, Sakuranori, Nikumukade, Tambanori, Tsurutsuru, Fudarak, Marubahdarak, Isonohana: Nurakusa, Ronulaksa, Oomkadenori, Hirakintoki: Hirakintoki, Matabou: Matabou, Kintoki: Chabokintoki, Kintoki, Matsunori, Rice, Tokamatsu, Hitomatsu, Fushikintoki, Tsunomude, Nagakinito, Crayfish Nagaobane: Naganobane, Funori genus: Hanafonori, Fukurofunori, Mafunori, Karekigusa: Karekigusa, Tosakamodoki: Hosobanatosakamodoki, Hironotosakamodoki, Yatsudegatatosakamodoki, Kurotosakamodokisane, Zotosofomoza Tosakamodoki, Nankaitosakamodoki, Himetosakamodoki, Kinuhada: Kinuhada, Ezotosaka: Ezotosaka, Tsukasanori: Enashikarimenia, Otsukasanori, Hana Tacarimenia, Hoonoo: Honoo, Hikagenoit: Hikagenoit, Usuginu, Nikuhounoo: Nikuhounoo, Venus nago, Venus nago, Susca veni: Suscabeni, Okarugusa: Yamadagusa, Mirin: Mirin, Hosokamiso , Isomocca genus: Isomocca, Yukari genus: Yukari, Hosoyukari, Ibaranori genus: Ibaranori, Saidaibara, Tachiibara, Kagibaranori, Kojinoo: Kizino-o, Isodantsu: Isodantsu, Atsubanori: Atsubanori, Ogonori, Ogonori, Ogori Mizo-okonori, birch, beniogonori, fukureshinori, purple birch, shinkaibanori, spruce birch, kataogonori, ryukyuogono Li, Atlantic scorpion, Ivy genus, Yumigataonori, Kubireogonori, Mosagogonori, Kinubanori, Amanita genus: Hachijotensamodoki, Fushikenori genus: Fushikenori, Namiiwatake, Nymphalanthus Itagususa, Saimi, Hari, Lotus Jigusa: Lotus Jigusa, Sugi nori: Ikanoashi, Hosoibonori, Nobonori, Black Haginansou Genus: gourd, cherries, octopus: octopus, sedge, genus: genus, genus: goat, dals : Dulse, Scorpionus, Anadalus, Weibusa: Uebusca, Benifronori: Benifuronori, Fusunagi: Futsutsunagi, Himefusunagi, Hirohafushitsugi, Otsunagisou, Hirawatagigi, Usuwasugi , Egonori: Egonori, Futogigi, Saeda: Saeda, Chirimomiji: Chirimomiji, Konohori family: Habutaenori, Konohori, Suzuronori, Usubeni: Genus: Kagios banori, Yareus banori, Susius banori, Heius banori, Usubanorimodoki: Usubanorimodoki, Ayanishiki genus: Ayani Genus: Aeginu, Dadia: Enasidadia, Shimadadia: Isohagi, Shimadadia, Dajimodoki: Dajimodoki, Euglena: Morayogusa, Fuyugusa, Makuri: Makri, Yanaginogi, Yuna, Yukinagina , Sasabayanaginori, Sozo genus: Kurosozo, Kobsozo, Hanesozo, Sozonohana, Hanegusa genus: Hananegusa, Hananegusa, Kozanemo genus: Kozanemo, Isomurasaki, Hosozozanemo, Himegoshigusu, Giant genus Isomagusa, Suginasugusa: Suginasusa, Isobashou: Isobasho, Fujimatsumo: Fujimatsumo, Sawweed: Haeshinosakiba, Kawamoku : Kawamoku, Aokawa Mozuku, Himekawa Mozuku, Ideyugogome: Ideyugogome, Okichimozuku: Okimozu, Otosa, Chinomo: Chinomo, Chisujinori, Chisujinori, etc.).

  Axial algae (Shajikumo, Shiratamamo, Hoshitsurimo: Hoshitsurimo, Rikunotumusu, Flaskmo: Himebumo, Chaboflasmo, Tripera, etc.), yellow algae (Hikarimo: Hikarimo, etc.), etc.

  In addition, the materials derived from animal materials include chicken crown extract, cow or pig, human placenta extract, cow or pig stomach, duodenum, intestine, spleen extract or decomposition product thereof, cow or pig brain tissue Extracts, cattle / pigs / fish collagen hydrolyzate (acid, alkali, enzyme etc.) degradation products, water-soluble collagen or collagen derivatives such as acylated collagen, cattle / pigs / fish elastin or elastin hydrolyzate (acid, Alkaline, enzyme, etc.) or water-soluble elastin derivative, keratin and its degradation product or their derivatives, silk protein and its degradation product or their derivatives, pig or cow blood cell protein degradation product (globin peptide), cow or pig hemoglobin Degradation products (hemin, hematin, heme, protoheme, heme iron, etc.), milk, casein and its degradation products or derivatives thereof, skim milk powder and its degradation products or it Derivatives, lactoferrin or decomposed product thereof, egg ingredients, fish hydrolyzate, nucleic acid-related substance (ribonucleic acid, deoxyribonucleic acid), or the like.

  In addition, as a material derived from a plant or animal material, any site, cell, tissue, organ, metabolite, etc. derived from a gene recombinant or a cell fusion can be used. Furthermore, for example, an undifferentiated cell group, a cell group in the middle of differentiation, or the like obtained by culturing an arbitrary site, cell, tissue, organ or the like can also be used.

(13) Marine components Seawater such as deep seawater, for example, sea salt, dried seawater, dead sea or Atlantic or Pacific seawater (sodium chloride, magnesium chloride, potassium chloride, etc.), sea mud or mud ( Fango), for example, Italian mud, German fungo, Eifelfango, Freiburg fungo, etc. Sea mud or mud from various locations (containing components: silicon dioxide, titanium dioxide, aluminum oxide, iron oxide, manganese oxide, sodium oxide, potassium oxide, Magnesium oxide, calcium oxide, strontium oxide, sodium, potassium, magnesium, calcium, chromium, iron, copper, nickel, zinc, lead, manganese, arsenic, water), saintoku stone, black meteorite, etc.

(14) Microbial culture metabolite Yeast metabolite, yeast extract, bacterial metabolite, bacterial extract, mold or actinomycete metabolite, mold or actinomycete extract, natto metabolite, natto extract, rice fermentation extract , Fermented extract of rice bran (red rice bran, white rice bran), Euglena extract or decomposition product thereof or water-soluble derivatives thereof, trehalose or derivative thereof, lactic acid fermentation product of raw milk or skim milk powder, fermented lactic acid bacteria of legumes, coconut plant Lactic acid bacteria fermented products.

(15) α-hydroxy acids Glycolic acid, citric acid, malic acid, tartaric acid, lactic acid and the like.

(16) Inorganic pigments Silicic anhydride, magnesium silicate, talc, kaolin, bentonite, mica, titanium mica, bismuth oxychloride, zirconium oxide, magnesium oxide, zinc oxide, titanium oxide, calcium carbonate, magnesium carbonate, yellow iron oxide, Bengala, black iron oxide, gunjo, chromium oxide, chromium hydroxide, carbon black, calamine, etc.

(17) UV absorber / blocker benzophenone derivatives (2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid, sodium 2-hydroxy-4-methoxybenzophenone-5-sulfonate, dihydroxy Dimethoxybenzophenone, dihydroxydimethoxybenzophenone-sodium sulfonate, 2,4-dihydroxybenzophenone, tetrahydroxybenzophenone, etc.), paraaminobenzoic acid derivatives (paraaminobenzoic acid, ethyl paraaminobenzoate, glyceryl paraaminobenzoate, amyl paradimethylaminobenzoate, Octyl paradimethylaminobenzoate), methoxycinnamate derivatives (ethyl paramethoxycinnamate, isopropyl paramethoxycinnamate, octyl paramethoxycinnamate, 2-ethoxycinnamic acid cinnamate) Til, sodium paramethoxycinnamate, potassium paramethoxycinnamate, diparamethoxycinnamate mono-2-ethylhexanoate glyceryl, etc.), salicylic acid derivatives (octyl salicylate, phenyl salicylate, homomenthyl salicylate, dipropylene glycol salicylate, ethylene glycol salicylate, myristyl salicylate, Methyl salicylate, etc.), anthranilic acid derivatives (methyl anthranilate, etc.), urocanic acid derivatives (urocanic acid, ethyl urocanate, etc.), coumarin derivatives, amino acid compounds, benzotriazole derivatives, tetrazole derivatives, imidazoline derivatives, pyrimidine derivatives, dioxane derivatives , Camphor derivative, furan derivative, pyrone derivative, nucleic acid derivative, allantoin derivative, nicotinic acid derivative, vitamin B6 derivative Body, umbelliferone, esculin, benzyl cinnamate, sinoxate, oxybenzone, dioxybenzone, octabenzone, thrisobenzone, benzoresorcinol, arbutin, guaiazulene, shikonin, baicalin, baicalein, berberine, neoheliopan, escalol, zinc oxide, talc, kaolin etc.

(18) Whitening agent Paraaminobenzoic acid derivative, salicylic acid derivative, anthranilic acid derivative, coumarin derivative, amino acid compound, benzotriazole derivative, tetrazole derivative, imidazoline derivative, pyrimidine derivative, dioxane derivative, camphor derivative, furan derivative, pyrone derivative, Nucleic acid derivatives, allantoin derivatives, nicotinic acid derivatives, vitamin C or derivatives thereof (vitamin C phosphate magnesium salt, vitamin C glucoside, etc.), vitamin E or derivatives thereof, kojic acid or derivatives thereof, oxybenzone, benzophenone, arbutin, guaiazulene, Shikonin, baicalin, baicalein, berberine, placenta extract, ellagic acid, lucinol, etc.

(19) Tyrosinase activity inhibitor Vitamin C or a derivative thereof (vitamin C phosphate magnesium salt, vitamin C glucoside, etc.), hydroquinone or a derivative thereof (hydroquinone benzyl ether, etc.), kojic acid or a derivative thereof, vitamin E or a derivative thereof, N-acetyltyrosine or its derivatives, glutathione, hydrogen peroxide, zinc peroxide, placenta extract, ellagic acid, arbutin, lucinol, silk extract, plant extract (camille, mulberry, gardenia, pearl oyster, walrus, clam, mugwort, honeysuckle) , Kihada, dokudami, matsuhod, pearl barley, nettle, hops, hawthorn, eucalyptus, yarrow, altea, keihi, mankaishi, hamamelis, karaguwa or yamagwa, proliferating grass, bellflower, toshishi, zetsugo, gyu, mao, sen Oxalic, Dokkatsu, Psycho, storm, littoralis, Scutellaria, peony bark, peony, cranesbill, kudzu root, licorice, Fushi aloe, Cimicifuga, safflower, green tea, black tea, Ali elixir), and the like.

(20) Melanin pigment reduction / decomposition substance Phenylmercury hexachlorophene, mercuric oxide, mercuric chloride, hydrogen peroxide, zinc peroxide, hydroquinone or its derivative (hydroquinone benzyl ether).

(21) Turnover promoting action / cell activator hydroquinone, lactic acid bacteria extract, placenta extract, ganoderma extract, vitamin A, vitamin E, allantoin, spleen extract, thymus extract, yeast extract, fermented milk extract, plant extract (aloe, Ogon, Japanese horsetail, Gentian, Burdock, Shikon, Carrot, Camelis, Hop, Yokuinin, Odori, Semburi, Japanese cypress, Japanese red snapper, Achacha, Hypericum, Cucumber, Necklace, Mannenrou, Parsley).

(22) Astringents Succinic acid, allantoin, zinc chloride, zinc sulfate, zinc oxide, calamine, zinc paraphenolsulfonate, potassium aluminum sulfate, resorcin, ferric chloride, tannic acid (including catechin compounds) and the like.

(23) Active oxygen scavenger
SOD, catalase, glutathione peroxidase and the like.

(24) Antioxidants Vitamin C or salts thereof, stearic acid ester, vitamin E or derivatives thereof, nordihydrogua ceretenoic acid, butylhydroxytoluene (BHT), butylhydroxyanisole (BHA), hydroxytyrosol, parahydroxyanisole , Propyl gallate, sesamol, sesamorin, gossypol, propolis, etc.

(25) Lipid peroxide production inhibitor β-carotene, plant extract (sesame culture cell, hamcha, hypericum, hamamelis, clove, melissa, birch, birch, salvia, mannenro, minamitenji, jitsu, ginkgo, green tea).

(26) Anti-inflammatory agent Ictamol, indomethacin, kaolin, salicylic acid, sodium salicylate, methyl salicylate, acetylsalicylic acid, diphenhydramine hydrochloride, d-camphor, dl-camphor, hydrocortisone, guaiazulene, camazulene, chlorpheniramine maleate, glycyrrhizic acid or its Salt, glycyrrhetinic acid or a salt thereof, licorice extract, sicon extract, age extract, propolis, etc.

(27) Antibacterial / bactericidal / disinfectant Acrinol, sulfur, calcium gluconate, chlorhexidine gluconate, sulfamine, mercurochrome, lactoferrin or hydrolyzate thereof, alkyldiaminoethylglycine chloride solution, triclosan, sodium hypochlorite, chloramine T, Sarashi powder, iodine compound, iodoform, sorbic acid or its salt, propionic acid or its salt, salicylic acid, dehydroacetic acid, parahydroxybenzoic acid esters, undecylenic acid, thiamine lauryl sulfate, thiamine lauryl nitrate, phenol, cresol, p -Chlorophenol, p-chloro-m-xylenol, p-chloro-m-cresol, thymol, phenethyl alcohol, O-phenylphenol, Irgasan CH3565, halocarban, hexachlorophene, chlorohexidine, ester Tanol, methanol, isopropyl alcohol, benzyl alcohol, ethylene glycol, propylene glycol, 2-phenoxyethanol, 1,2-pentanediol, zinc pyridione, chlorobutanol, isopropylmethylphenol, nonionic surfactant (polyoxyethylene lauryl ether, Polyoxyethylene nonyl phenyl ether, polyoxyethylene octyl phenyl ether, etc.), amphoteric surfactant, anionic surfactant (sodium lauryl sulfate, lauroyl sarcosine potassium, etc.), cationic surfactant (cetyltrimethylammonium bromide, benzalkco chloride) Nium, benzethonium chloride, methyl rosaniline chloride), formaldehyde, hexamine, brilliant green, malachite green, crystal bio Tsu DOO, Jamaru photosensitive No. 101-containing, photosensitizer No. 201, photosensitizer No. 401, N- long chain acyl basic amino acid derivative and its acid shark salts, zinc oxide, hinokitiol, Sophora root, propolis, and the like.

(28) Moisturizer Glycerin, propylene glycol, 1,3-butylene glycol, polyethylene glycol, glycerin tricaprycapric acid, glycolic acid (α-hydroxy acid), hyaluronic acid or its salt, chondroitin sulfate or its salt, water-soluble chitin or Derivatives or chitosan derivatives, pyrrolidone carboxylic acids or salts thereof, sodium lactate, urea, sorbitol, amino acids or derivatives thereof (valine, leucine, isoleucine, threonine, methionine, phenylalanine, tryptophan, lysine, glycine, alanine, asparagine, glutamine, serine , Cysteine, cystine, tyrosine, proline, hydroxyproline, aspartic acid, glutamic acid, hydroxylysine, arginine, ornithine, histidine and their sulfates Phosphate, nitrate, citrate, or pyrrolidone carboxylic acid), oils and fats “Avocado oil, almond oil, fennel oil, sesame oil, olive oil, orange oil, orange rafa oil, sesame oil, cocoa butter, chamomile oil, carrot oil , Cucumber oil, beef tallow fatty acid, quince seed oil, cucumber seed oil, safflower oil, shea fat, liquid shea fat, soybean oil, camellia oil, corn oil, rapeseed oil, jojoba oil, persic oil, castor oil, sunflower oil, cottonseed oil , Peanut oil, turtle oil, tea tree oil, mink oil, egg yolk oil, palm oil, palm kernel oil, molasses, coconut oil, eucalyptus oil, beef tallow, squalene, squalane, pristane or hydrogenated products of these oils and fats ( Hardened oil) ”, waxes (beeswax, carnauba wax, whale wax, lanolin, liquid lanolin, reduced lath Norin, hard lanolin, candelilla wax, montan wax, shellac wax, rice wax), mineral oil (liquid paraffin, petrolatum, paraffin, ozokelide, ceresin, microcristan wax), natto bacteria metabolites, natto extract, silk fiber extract, plant extract (Akamatsu sap, aloe, kudzu, chamomile, licorice, cucumber, licorice, rice or rice bran, purple root, birch or birch sap, assembly, mulberry white skin, birch leaf, loofah, peony skin, persimmon) and the like.

(29) Elastase activity inhibitor Diisopropyl fluorophosphate, plant extract (eg, gongoid, hypericum, clara, mulberry leaves, keihi, genokosho, comfrey, salvia, elderberry, bodaiju, button pi), seaweed extract and the like.

(30) Hair preparations Selenium disulfide, alkylisoquinolinium bromide solution, zinc pyrithione, biphenamine, thianthol, castari tincture, pepper tincture, pepper tincture, quinine hydrochloride, strong ammonia water, potassium bromate, sodium bromate, thio Glycolic acid and the like.

(31) Antiandrogens Follicular hormones (estrone, estradiol, ethinyl estradiol, etc.), isoflavones, oxendrone, etc.

(32) Peripheral vascular blood flow promoter Vitamin E or derivatives thereof, assembly extract, garlic extract, carrot extract, aloe extract, gentian extract, toki extract, cephalanthin, carpronium chloride, minoxidil and the like.

(33) Stimulants Pepper tincture, nonyl acid vanillamide, cantalis tincture, ginger tincture, peppermint oil, l-menthol, camphor, benzyl nicotinate and the like.

(34) Metabolic activator Photosensitive element 301, hinokitiol, pantothenic acid or derivatives thereof, allantoin, placental extract, biotin, pentadecanoic acid glyceride and the like.

(35) Antiseborrheic agent Pyridoxine or a derivative thereof, sulfur, vitamin B6 and the like.

(36) Keratolytic agent Resorcin, salicylic acid, lactic acid, urea and the like.

(37) Oxidizing agent Hydrogen peroxide solution, sodium persulfate, ammonium persulfate, sodium perborate, urea peroxide, sodium percarbonate, sodium tripolyphosphate, sodium bromate, potassium bromate, sodium pyrophosphate, Sodium orthophosphate, sodium silicate hydrogen peroxide adduct, sodium sulfate hydrogen peroxide adduct, sodium chloride hydrogen peroxide adduct, β-tyrosinase enzyme solution, mushroom extract, etc.

(38) Depilatory agents Inorganic reducing agents such as strontium sulfate, sodium sulfide, barium sulfide, calcium sulfide, thioglycolic acid or its salts (calcium thioglycolate, sodium thioglycolate, lithium thioglycolate, magnesium thioglycolate) Strontium thioglycolate) and the like.

(39) Hair swelling agents such as ethanolamine, urea and guanidine.

(40) Dye agent
5-aminoorthocresol, 2-amino-4-nitrophenol, 2-amino-5-nitrophenol, 1-amino-4-methylaminoanthraquinone, 3,3'-iminodiphenol, 2,4-diaminophenoxyethanol hydrochloride 2,4-diaminophenol hydrochloride, toluene-2,5-diamine hydrochloride, nitroparaphenylenediamine hydrochloride, paraphenylenediamine hydrochloride, N-phenylparaphenylenediamine hydrochloride, metaphenylenediamine hydrochloride, orthoaminophenol, N-phenyl acetate Paraphenylenediamine, 1,4-diaminoanthraquinone, 2,6-diaminopyridine, 1,5-dihydroxynaphthalene, toluene-2,5-diamine, toluene-3,4-diamine, nitroparaphenylenediamine, paraaminophenol, para Nitroorthophenylenediamine, paraphenylenediamine, paramethylamino Phenol, picramic acid, sodium picramate, N, N'-bis (4-aminophenyl) -2,5-diamino-1,4-quinonediimine, 5- (2-hydroxyethylamino) -2-methylphenol, N -Phenylparaphenylenediamine, metaaminophenol, metaphenylenediamine, 5-aminoorthocresol sulfate, 2-amino-5-nitrophenol sulfate, orthoaminophenol sulfate, orthochloroparaphenylenediamine sulfate, 4,4'-diamino sulfate Diphenylamine, 2,4-diaminophenol sulfate, toluene-2,5-diamine sulfate, nitroparaphenylenediamine sulfate, paraaminophenol sulfate, paranitroorthophenylenediamine sulfate, paranitrometaphenylenediamine sulfate, paraphenylenediamine sulfate, parasulfate sulfate Methylaminophenol, metaaminosulfate Diol, metaphenylenediamine sulfate, catechol, diphenylamine, α-naphthol, hydroquinone, pyrogallol, phloroglucin, gallic acid, resorcin, tannic acid, 2-hydroxy-5-nitro-2 ', 4'-diaminoazobenzene-5'-sulfone Sodium acid, hematein, etc.

(41) Fragrance Natural animal fragrance such as musk, civet, castorium, ambergris, anise essential oil, angelica essential oil, ylang ylang essential oil, iris essential oil, fennel essential oil, orange essential oil, cananga essential oil, caraway essential oil, cardamom essential oil, guayakwood essential oil, Cumin essential oil, black letter essential oil, cinnamon essential oil, cinnamon essential oil, geranium essential oil, copaiba balsam essential oil, coriandel essential oil, perilla essential oil, cedarwood essential oil, citronella essential oil, jasmine essential oil, gingergrass essential oil, cedar essential oil, spearmint essential oil, western peppermint essential oil, Otsuka perfume essential oil, tuberose essential oil, clove essential oil, orange flower essential oil, winter green essential oil, trout balsam essential oil, buttery essential oil, rose essential oil, palmarosa essential oil, persimmon essential oil, hiba essential oil, sandalwood essential oil, petit gren essential oil, bay essential oil, vetiva essential oil, bergamot Spirit , Peru balsam essential oil, boad rose essential oil, melamine essential oil, mandarin essential oil, eucalyptus essential oil, lime essential oil, lavender essential oil, linaloe essential oil, lemongrass essential oil, lemon essential oil, rosemary (mannenrou) essential oil, Japanese mint mint essential oil Other synthetic fragrances.

(42) Dye and Colorant Red Cabbage Dye, Red Rice Dye, Akane Dye, Anato Dye, Ikumi Dye, Turmeric Dye, Enju Dye, Krill Dye, Amber Dye, Caramel, Gold, Silver, Gardenia Dye, Corn Dye, Onion Dye , Tamarind pigment, spirulina pigment, buckwheat whole plant pigment, cherry pigment, laver pigment, hibiscus pigment, grape juice pigment, marigold pigment, purple potato pigment, purple yam pigment, lac pigment, rutin etc.

(43) Others Hormones, sequestering agents, pH adjusters, chelating agents, antiseptic and antibacterial agents, cooling agents, stabilizers, emulsifiers, animal and vegetable proteins and their degradation products, animal and vegetable polysaccharides And its degradation products, animal and plant glycoproteins and their degradation products, blood flow promoters, anti-inflammatory agents, anti-inflammatory agents, anti-allergic agents, wound treatment agents, foam increasing agents, thickeners, enzymes, purified water (electronic Water, small clustering, etc.), oral preparations, deodorizing / deodorizing agents, bittering agents, seasonings, etc., and in combination with these, additive or synergistic effects of the present invention or other cosmetic effects Improvement can be expected.

  EXAMPLES Next, although an Example is given and this invention is demonstrated further in detail, this invention is not necessarily limited to these.

[1] Production of lanosteryl-o-methylglucoside alkyl ester (LMG-AE) LMG (20 parts) and DMSO (70 parts) were placed in a reactor, heated to boil DMSO under a pressure of 2.67 KPa, A part of the steam is distilled to remove moisture in the system. Subsequently, AE (4 parts) and anhydrous potassium carbonate (0.06 parts) were added to the reactor, and the mixture was reacted at about 90 ° C. under a pressure of 2.67 KPa for 3 hours. After completion of the reaction, 50% -lactic acid aqueous solution (about 0.14 parts) was added to neutralize the reaction system. Next, DMSO was evaporated and concentrated under reduced pressure, and water and isobutyl alcohol were added thereto for extraction. The organic solvent was recovered, washed several times with water, and the organic solvent was distilled off to remove LMG-AE ( Table 1) was obtained.

[2] Manufacture of sitosterol alkyl ester (S-AE) Commercially available chemicals or reagents can be used, but using a general organic synthesis method (carboxylic acid-alcohol dehydration condensation reaction), S and a linear or branched saturated fatty acid (FA) having 6 to 30 carbon atoms are ester-synthesized. In addition, it can also be obtained by reacting S with a linear or branched saturated fatty acid chloride (FAC) having 6 to 30 carbon atoms in the presence of an alkali. In a solvent DMSO, equimolar amounts of S and FA are added and reacted at an appropriate temperature (30 to 50 ° C.) for 1 to 5 hours, or S and FAC are reacted in an equimolar amount in the presence of an alkali and difficult to water. S-AE (Table 2) was obtained by liquid-liquid separation extraction and purification with a soluble organic solvent having a boiling point lower than that of DMSO and water.

[3] Production of sitosteryl glucoside alkyl ester (SG-AE) SG-AE (Table 4) was obtained in the same manner as in Example 1 except that SG was used instead of LMG.

  The hair lotions having the compositions shown in Tables 1 to 4 below were prepared, and the effects on damaged hair (bleached and permanent wave agent treated) on the cut hair (breaking strength and elongation) were evaluated by the following methods. The results are shown in Tables 1-4.

〔Evaluation methods〕
Bleach hair (25% ammonia water 4 mL, 30% hydrogen peroxide solution 13 mL, purified water added to 100 mL bleaching agent for 40 hours at 40 ° C. for 12 hours), permanent wave 1 agent (thioglycolic acid) After soaking at 40 ° C. for 10 minutes in 6 g of sodium, 2 g of 25% aqueous ammonia, and 100 mL of purified water), washed with water (40 ° C., 1 minute), permanent wave 2 agent (6 g of sodium bromate, The hair soaked in purified water (100 mL) at 25 ° C. for 10 minutes is immersed in a hair lotion at 40 ° C. for 30 minutes, and subjected to a tensile test (hair length 70 mm, tensile speed 50 mm / min). And the elongation was measured.

  Shampoos having the compositions shown in Table 5 below were prepared, each was washed with hair, and the hair after being dried was evaluated for the squeaky feeling, softness, suppleness, and styling properties by the following methods. The results are shown in Table 5.

〔Evaluation methods〕
For female panelists with long or semi-long hair that have permanent wave treatment, hair dyeing, and hair color treatment, we conducted a shampoo usage test as usual, and after rinsing and drying with a dryer, The following criteria were used to evaluate the texture, suppleness and styling.
Hair squeaky and crisp feeling ◎: Good sensation without squeaky and rusty feeling.
○: The feeling of tingling and rustling is somewhat improved.
Δ: The feeling of tingling or rustling is the same as before use.
X: A feeling of tingling and rustling is felt more.
A feeling of suppleness of hair ◎: Good and supple feeling.
○: There is a supple feeling.
Δ: Almost no supple feeling (before use).
X: Loss of suppleness.
Hair styling ◎: Good styling.
○: Styling is slightly better.
(Triangle | delta): Styling property is normal (it does not change before use).
X: The styling property is poor.

  According to said evaluation result, the example of a prescription is shown below, but each prescription example may be manufactured by the conventional method in manufacture of each product, and showed only the compounding quantity. The present invention is not limited to these.

(Formulation Example 1) Shampoo Mass%
POE (3) sodium lauryl ether sulfate 13.0
Sodium lauryl glyceryl sulfate 2.0
Sodium lauryl sulfate 2.0
Sodium laurylaminopropionate 3.0
γ-keratose hydrolyzate (MW 35000) 3.0
Lauryldimethylamine oxide 1.0
Glycerin fatty acid ester 1.0
Hydroxyethyl cellulose 1.0
Cationized cellulose 0.2
Piroctone Olamine 0.5
Highly polymerized dimethyl silicone 3.0
Glycine 0.2
Glycerin 1.0
1,3-butylene glycol 0.5
Sodium benzoate 1.0
Methylparaben 0.2
Allantoin 0.2
LMG-AE (methylpentadecanoate) of the present invention 0.5
Pigment proper amount Perfume proper amount Citric acid 0.5
Purified water remaining

(Prescription Example 2) Shampoo Mass%
POE (3) sodium lauryl ether sulfate 4.0
Lauroylmethyl-β-alanine triethanolamine salt 5.0
Cocoyl glutamic acid triethanolamine salt 5.0
Laurylamidopropylbetaine 5.0
Dodecylaminopropionic acid 1.0
POE hydrogenated castor oil (40) 2.0
LMG-AE (pentadecanoic acid ester) of the present invention 0.5
Decyl glyceryl glucoside 1.0
Water-soluble silk protein hydrolyzate 0.2
Glycerin laurate 3.0
Polydimethylsiloxane 4.0
Cetyl isooctanoate 3.0
Wax 1.0
Cationized cellulose 0.4
Piroctone Olamine 0.5
Ethanol 3.0
Dipropylene glycol 0.5
Sodium chloride 1.0
Sodium benzoate 0.3
Paraben 0.2
Perfume appropriate amount Citric acid 1.5
Purified water remaining

(Prescription Example 3) Shampoo Mass%
POE (2.5) sodium tridecyl ether sulfate 10.0
C14-α-olefin sulfonic acid sodium salt 5.0
Sodium paraffin sulfonate 1.0
Amidopropyl betaine laurate 2.0
Dodecylcarboxyethyl hydroxyethyl betaine 1.0
POE (15) dodecyl ether 3.0
POE hydrogenated castor oil (40) 3.0
SG (sitosteryl glucoside) of the present invention 0.5
Dodecylglycerin ether 2.0
Dimethylsiloxane 2.0
Cetyl isooctanoate 1.0
Glycerin 1.0
Dimethyldiallylammonium chloride / acrylamide copolymer 0.3
Collagen-derived tripeptide 0.5
Catechin 0.1
Chamomile extract 0.3
Cetanol 2.0
Sodium citrate 0.2
Paraben 0.2
Methyl isothiazoline and methyl chloro isothiazoline 0.03
Polyethylene glycol 2.0
Citric acid 0.8
Purified water remaining

(Formulation example 4) Rinse mass%
Amide amino acid type amphoteric activator 5.0
Cetanol 3.0
Sodium hyaluronate 0.5
Rice fermentation extract 0.2
Cationized polyvinyl polymer 0.1
Vaseline 0.5
Hydroxyethyl cellulose 0.8
SG-AE (oleic acid ester) of the present invention 0.1
Propylene glycol 4.0
Perfume appropriate amount Citric acid 1.3
Purified water remaining

(Formulation example 5) Rinse mass%
Alkyldipolyoxyethyleneethylenemethylammonium chloride 4.0
Cetanol 2.5
Cationized polyacrylic polymer 0.3
Glycerin 3.5
Polyoxyethylene cetyl ether 0.5
Dimethylpolysiloxane 2.0
α-keratose (MW 20000 to 40000) 2.0
S-AE (palmitate) of the present invention 0.1
Inositol 0.5
Water-soluble fish skin collagen 0.3
Polyethylene glycol (MW200000) 0.2
1,3-butylene glycol 3.0
Perfume appropriate amount Citric acid 1.3
Purified water remaining

(Formulation example 6) Rinse mass%
Lauryldimethylamine oxide 4.0
Cetanol 3.0
Astaxanthin 0.2
Brown algae extract 0.3
10% -Carboxymethylchitin aqueous solution 0.4
Sorbitol 3.0
Polyoxyethylene cetyl ether (EO3.0) 0.6
Hydroxyethyl cellulose 1.0
LMG-AE (stearic acid ester) of the present invention 0.3
Polypropylene glycol 3.0
Perfume appropriate amount Citric acid 0.5
Purified water remaining

(Formulation example 7) Rinse mass%
Amide amino acid type amphoteric activator 4.0
Cetanol 3.0
Quercetin 0.2
Tocopherol acetate 0.1
Polyoxyethylene cetyl ether (EO3.0) 0.5
SG-AE (palmitoleic acid ester) of the present invention 0.3
1,2-hexanediol 1.0
Xylitol 3.5
Hydroxyethyl cellulose 0.8
BHT 0.1
Perfume appropriate amount Lactic acid 0.3
Purified water remaining

(Prescription Example 8) Rinse mass%
Cetostearyl alcohol 3.0
Isocetyl myristate 2.0
Arginine derivative 2.0
α-keratose hydrolyzate alkyl cationized derivative 3.0
(MW 46000)
(Hydroxypropyltrimethylammonium addition)
Methyl polysiloxane 1.0
Amino-modified silicone 1.0
Arnica extract 1.0
LMG-AE (lauric acid ester) of the present invention 0.5
Polyethylene glycol 1.0
Perfume appropriate amount Preservative appropriate amount Purified water remaining

(Prescription Example 9) Hair Treatment Mass%
Glyceryl triethylhexanoate 3.0
Methylphenylpolysiloxane 1.0
Dimethylpolysiloxane 2.0
Polyether-modified organopolysiloxane polymer 2.0
Stearyl alcohol 1.5
Behenyl alcohol 0.5
Stearyltrimethylammonium chloride 1.0
1,3-butylene glycol 7.0
Cationized cellulose 0.2
LMG-AE (Lauroleic acid ester) of the present invention 0.5
Water-soluble collagen 0.01
Nicotinic acid 0.2
Phenoxyethanol 0.5
Perfume Appropriate amount Purified water Remaining

(Prescription Example 10) Hair Treatment Mass%
1,3-butanediol 5.0
γ-polyglutamate sodium 0.02
Methylparaben 0.2
Cetyltrimethyl chloride 2.0
Dimethyl distearyl chloride 3.0
Castor oil 1.0
Neopentyl glycol diisooctanoate 5.0
Liquid paraffin 8.0
Cetanol 6.0
Dimethylpolysiloxane 1.0
Aminoethylaminopropylsiloxane
Methylsiloxane copolymer 2.0
SG-AE (myristic acid ester) of the present invention 1.0
Phenoxyethanol 0.3
Chlorogenic acid 0.2
Purified water remaining

(Prescription Example 11) Treatment Mass%
Glyceryl tri-2-ethylhexanoate 3.0
Methylphenylpolysiloxane 1.0
Dimethylpolysiloxane 2.0
Partially cross-linked polyether-modified organopolysiloxane polymer 2.0
Stearyl alcohol 1.5
Behenyl alcohol 0.5
Stearyltrimethylammonium chloride 1.0
LMG-AE (palmitate) of the present invention 0.2
1,3-butylene glycol 7.0
Water-soluble carboxymethyl-1,3-β glucan 0.02
Methionine 0.3
Aspartic acid 0.02
Lactic acid bacteria fermented milk extract 0.5
Methyl paraoxybenzoate Appropriate amount Perfume Appropriate amount Purified water Remaining

(Formulation example 12) Hair artnic mass%
Polyoxyethylene hydrogenated castor oil 1.0
Shower tincture 1.0
Isopropyl methylphenol 0.05
Salicyl alcohol calcium 0.2
Eucommia extract 0.4
LMG-AE (myristic acid ester) of the present invention 0.05
Glycerin 2.0
Ethanol 50.0
Purified water remaining

(Formulation example 13) Hair cream mass%
Organopolysiloxane 15.0
Stearic acid 0.5
Squalane 5.0
Glycerin 5.0
POE (20) cetyl ether 1.5
POE (2) cetyl ether 2.5
Sorbitan monostearate 1.5
Glyceryl monostearate 0.5
Triethanolamine 0.2
Polyvinylpyrrolidone 5.0
Propylene glycol 10.0
SG-AE (lauric acid ester) of the present invention 0.1
1,2-pentanediol 0.5
Tocopherol acetate 0.2
Aloe extract 0.1
Ethyl paraoxybenzoate Appropriate amount Perfume Appropriate amount Purified water Remaining

(Formulation Example 14) Hair Cream Mass%
Liquid paraffin 10.0
Squalane 7.0
Jojoba oil 3.0
Solid paraffin 3.0
Polyoxyethylene cetyl ether 2.0
LMG-AE (docosanoic acid ester) of the present invention 0.05
γ-aminobutyric acid 0.2
SOZUKU EXTRACT 0.2
Sorbitan sesquioleate 1.0
Potassium hydroxide 0.1
Glycerin 3.0
Ethylparaben 0.1
Purified water remaining

(Formulation Example 15) Hair Oil Mass%
Decamethylcyclopentasiloxane 70.0
Green tea extract 0.2
Perilla extract 0.3
Trichlorotrifluoroethane 7.0
Isopropyl alcohol 3.0
Dimethylpolysiloxane 4.0
Panthenol 0.1
LMG-AE (methylpentadecanoic acid ester) of the present invention 0.03
Soy lecithin 1.0
Perfume appropriate amount Ethanol remaining amount

(Prescription Example 16) Hair set lotion% by mass
Vinylpyrrolidone / N, N-dimethylaminoethyl
Methacrylic acid copolymer diethyl sulfate 1.0
Astragalus extract 0.3
Polyoxyethylene hydrogenated castor oil 0.3
γ-keratose hydrolyzate alkyl cationized derivative 1.0
(MW 38000)
(Hydroxypropyl lauryl dimethyl ammonium addition)
N-acetylneuraminic acid 0.1
LMG-AE (methylpentadecanoate) of the present invention 0.02
SG (sitosteryl glucoside) of the present invention 0.01
Diethylene glycol 1.0
Hexanediol 0.5
Kumazasa Extract 0.2
Ethanol 20.0
Perfume appropriate amount Preservative appropriate amount Purified water remaining

(Prescription Example 17) Hair Styling Gel Mass%
N-methacryloylethyl N, N-dimethyl
Ammonium α-N-methylcarboxybetaine
-Alkyl methacrylate copolymer 1.0
Vinylpyrrolidone / vinyl acetate copolymer 0.2
4% -hydroxypropylchitosan aqueous solution 0.5
Sodium γ-polyglutamate 0.01
Carboxyvinyl polymer 0.5
S-AE (stearic acid ester) of the present invention 0.5
Glycerin 0.5
Tannic acid 0.01
Naringenin 0.4
Ethanol 18.0
Diisopropanolamine 0.4
Perfume appropriate amount Preservative appropriate amount Purified water remaining

(Prescription Example 18) Hair foam mass%
Alkyl-modified organopolysiloxane 10.0
Mixed plant extract (Arnica, Nettle, Cucumber, Atlantic Kizuta,
Mallow, elderberry) 1.0
Ogon Extract 0.1
Polyoxyethylene hydrogenated castor oil (60EO) 0.5
Polyoxyethylene cetyl ether (10EO) 0.3
LMG-AE (palmitoleic acid ester) of the present invention 0.05
Sodium pyrrolidonecarboxylate 0.5
Panthenol 0.01
Polyethylene glycol 1.0
Chondroitin sulfate sodium 0.02
Purified water remaining

(Formulation example 19) Hair mist mass%
Dimethylpolysiloxane 10.0
Aminoguanidine 0.2
Dipotassium glycyrrhizinate 0.001
Black tea extract 0.1
Mixed plant extract (Clara, Showa, Senkyu, Tokyo,
Peach, ginseng) 0.5
LMG-AE (capric acid ester) of the present invention 0.05
Glycerin 0.1
Ethanol 50.0
Propylene glycol 2.0
Methylphenylpolysiloxane 0.01
Purified water remaining

(Prescription Example 20) Hair wax Mass%
Decaglyceryl diisostearate 5.0
Carboxyvinyl polymer 0.5
Xanthan gum 0.3
Methylsiloxane / polyoxyethylene copolymer 2.0
Vaseline 3.0
Shea fat 2.0
Tocopheryl glucoside 0.2
Hydroxytyrosol 0.1
Ginkgo biloba extract 0.3
Candelilla Row 1.0
Polyoxyethylene octyldodecyl ether 0.3
Polyoxypropylene diglyceryl ether 4.0
Dihydroxybenzophenone 0.1
Propylparaben 0.1
Phenoxyethanol 0.5
Benzalkonium chloride 0.05
Edetate tetrasodium 0.05
Triethanolamine 0.5
LMG-AE (pentadecanoic acid ester) of the present invention 0.01
SG-AE (oleic acid ester) of the present invention 0.01
Glycerin 5.0
Perfume Appropriate amount Purified water Remaining

(Prescription Example 21) Hair dye mass%
(First agent)
Paraaminophenol 1.0
Paraaminoorthocresol 1.1
28% by weight ammonia water 5.0
Monoethanolamine 2.0
Cetanol 8.5
Polyoxyethylene (40) cetyl ether 3.0
Polyoxyethylene (2) cetyl ether 3.5
Stearyltrimethylammonium chloride 2.0
Sodium sulfite 0.05
Ascorbic acid 2-glucoside 0.01
Edetate tetrasodium 0.1
LMG-AE (methylpentadecanoic acid ester) of the present invention 0.1
1,3-butylene glycol 0.5
Perfume Appropriate amount Ammonium chloride Appropriate amount Purified water Remaining amount (second agent)
35% by weight hydrogen peroxide solution 17.1
Methylparaben 0.1
Phosphoric acid Suitable amount Purified water Remaining

(Formulation Example 22) 1-part hair dye mass%
Alloxan 1.0
Ethanol 25.0
Benzyl alcohol 3.0
Glycolic acid 3.0
Succinic acid 5.0
SG (sitosteryl glucoside) of the present invention 0.01
S-AE (palmitate) of the present invention 0.01
Diethylene glycol 0.5
Black No. 401 0.007
Purple No. 401 0.008
Orange No. 205 0.035
Carboxymethylchitin 1.5
Sodium hydroxide appropriate amount Glycine 1.0
Arginine 0.3
Tyrosine 0.3
Anise extract 0.5
Purified water remaining

(Prescription Example 23) Hair nail polish
Benzyl alcohol 8.0
Phenoxyethanol 1.0
Astaxanthin fatty acid ester 0.2
Hydrocortisone butyrate 0.2
Acrylic acid / alkyl methacrylate copolymer 1.0
Xanthan gum 1.2
Methyl polysiloxane 1.0
Liquid paraffin 5.0
Edetate disodium 0.02
LMG-AE (myristic ester) of the present invention 0.1
Dipropylene glycol 5.0
Ethanol 24.0
Citric acid 1.0
Triethanolamine appropriate amount Red No. 504 0.25
Orange 205 No. 0.05
Purified water remaining

(Formulation Example 24) Permanent wave agent mass%
(First agent)
Ammonium thioglycolate 6.0
γ-keratose hydrolyzate (MW 35000) 5.0
S-AE (lauric acid ester) of the present invention 0.02
LMG-AE (Lauroleic acid ester) of the present invention 0.02
Sorbitol 0.5
Ergosterol 0.2
Glucosylceramide 0.3
Artemisia extract 0.2
Monoethanolamine 0.8
Ammonia water (25%) 1.0
Emulsifier 1.0
Palm oil fatty acid diethanolamide 0.3
Edetate disodium 0.1
Perfume Appropriate amount Purified water Remaining amount (second agent)
Sodium bromate 10.0
Purified water remaining

(Prescription Example 25) Hair Straightener
(First agent)
Ammonium thioglycolate 8.0
Polyoxyethylene / methylpolysiloxane copolymer 2.0
Hosobabarengiku extract 0.5
Dutch mustard extract 0.5
Ammonium dithiodiglycolate 2.0
28% ammonia water 1.0
Monoethanolamine 3.0
Carboxyvinyl polymer 1.0
Safflower oil 1.0
Rice germ oil 0.5
POE (10) oleyl ether 1.2
SG-AE (palmitate) of the present invention 0.02
1,3-butylene glycol 1.5
Perfume Appropriate amount Purified water Remaining amount (second agent)
Sodium bromate 10.0
Cetanol 6.0
Liquid paraffin 4.0
POE (15) cetyl ether 0.5
POE (2) stearyl ether 3.0
Purified water remaining

(Prescription Example 26) Hair straightener
(First agent)
Ammonium thioglycolate 7.0
γ-keratose hydrolyzate (MW 21200) 4.5
Apple extract 0.3
PERBIANBERG EXTRACT 0.3
Monoethanolamine 2.0
Hydroxyethyl cellulose 2.0
Stearyltrimethylammonium chloride 0.5
Alanine 2.0
Hydroxyproline 1.0
Alkyl-modified organopolysiloxane 2.0
Perfume Appropriate amount Purified water Remaining amount (second agent)
Sodium bromate 10.0
Cetanol 8.0
Cypress extract 0.5
LMG-AE (methylpentadecanoate) of the present invention 0.02
Glycerin 4.0
Polyoxyethylene cetyl ether 4.5
Oolongcha Extract 3.0
Glutamic acid 2.0
Methylphenyl polysiloxane 0.5
Trehalose 0.1
Phosphoric acid Suitable amount Purified water Remaining

(Formulation example 27) 1 agent type permanent wave agent
Ammonium thioglycolate 13.0
Leucine 2.0
Mixed plant extract (burdock root, bonnet, hypericum perforatum, salvia milkweed, hops, lemon) 1.0
Carboxyvinyl polymer 0.5
Oleyl alcohol 3.5
S-AE (palmitate) of the present invention 0.05
LMG-AE (pentadecanoic acid ester) of the present invention 0.05
1,3-butanediol 1.5
Divinyl polydimethylsiloxane 0.3
Perfume appropriate amount Ammonia appropriate amount Purified water remaining

  Using the hair set lotion of Formulation Example 16 and the hair mist of Formulation Example 19, a use test was conducted by a panel of hair quality damaged by perm, bleach or the like. As a result, it was evaluated that all of them had a good feeling of suppleness and a good styling property as well as preventing creaking, dryness, and nicks on the hair after drying.

Claims (2)

Formula Ranosuteriru -o- methyl glucoside alkyl ester represented by 1, the hair cosmetic containing one or more sterol derivative selected from among a citrate sterylglucoside alkyl ester represented by one general formula 4.

: (General formula 1 )

: (General formula 4)
[Wherein R ₁ and R ₃ represent a linear or branched saturated alkyl group or unsaturated alkyl group (alkenyl group) having 6 to 30 carbon atoms. ]   Further, ethylene glycol, diethylene glycol, triethylene glycol, polyethylene glycol, propylene glycol, dipropylene glycol, 2-amino-2-methyl-1,3-propanediol, 1,2-propanediol, 1,3-propanediol, Polypropylene glycol, 1,3-butylene glycol, 1,2-butanediol, 1,3-butanediol, 1,4-butanediol, isopentanediol, pentylene glycol, hexylene glycol, 1,2-pentanediol, 1 , 3-pentanediol, 1,4-pentanediol, 1,5-pentanediol, 1,2,3-pentanetriol, 2,3,4-pentanetriol, 1,3,4-pentanetriol, 1,3 , 5-Pentanetrio 1,2-hexanediol, 1,3-hexanediol, 1,4-hexanediol, 1,5-hexanediol, 1,6-hexanediol, 1,2,3-hexanetriol, 1,3,4 -Hexanetriol, 1,3,5-hexanetriol, 1,4,6-hexanetriol, 2-ethyl-1,3-hexanediol, glycerin, erythritol, pentaerythritol, dipentaerythritol, threitol, arabitol, xylitol , Ribitol, galactitol, sorbitol, mannitol, lactitol, maltitol, inositol, panthenol, laminitol, varienamine, validamine, validamine, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, diethylene Glycol monomethyl ether, polyhydric alcohol or hair cosmetic according to claim 1, further comprising a lower alkyl ester thereof selected from diethylene glycol monoethyl ether.