JP4790179B2 - 破骨細胞活性を阻害する方法 - Google Patents
破骨細胞活性を阻害する方法 Download PDFInfo
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Classifications
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- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
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- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- C07K—PEPTIDES
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- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
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- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Organic Chemistry (AREA)
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- Public Health (AREA)
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- Engineering & Computer Science (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biochemistry (AREA)
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- Genetics & Genomics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Pain & Pain Management (AREA)
- Marine Sciences & Fisheries (AREA)
- Toxicology (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14609499P | 1999-07-28 | 1999-07-28 | |
| US60/146,094 | 1999-07-28 | ||
| PCT/US2000/020502 WO2001008677A1 (en) | 1999-07-28 | 2000-07-28 | Methods of inhibiting osteoclast activity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003505503A JP2003505503A (ja) | 2003-02-12 |
| JP2003505503A5 JP2003505503A5 (OSRAM) | 2011-03-03 |
| JP4790179B2 true JP4790179B2 (ja) | 2011-10-12 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001513407A Expired - Fee Related JP4790179B2 (ja) | 1999-07-28 | 2000-07-28 | 破骨細胞活性を阻害する方法 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1207873B1 (OSRAM) |
| JP (1) | JP4790179B2 (OSRAM) |
| AT (1) | ATE448781T1 (OSRAM) |
| AU (2) | AU778190B2 (OSRAM) |
| CA (2) | CA2380007A1 (OSRAM) |
| DE (1) | DE60043346D1 (OSRAM) |
| WO (1) | WO2001008677A1 (OSRAM) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU777634B2 (en) * | 1999-07-28 | 2004-10-28 | Kazuhiro Aoki | Methods of inhibiting osteoclastogenesis |
| CA2423052C (en) | 2000-09-22 | 2011-07-12 | Immunex Corporation | Screening assays for agonists or antagonists of receptor activator of nf-kb |
| EP1401851B8 (de) | 2001-07-03 | 2008-09-10 | febit holding GmbH | Zweistufige schutzgruppen für die synthese von biopolymeren |
| KR101560844B1 (ko) * | 2007-06-04 | 2015-10-15 | 벤-구리온 유니버시티 오브 더 네게브 리서치 앤드 디벨럽먼트 어쏘러티 | 트라이-아릴계 화합물 및 이를 포함하는 조성물 |
| JP5191487B2 (ja) | 2007-06-05 | 2013-05-08 | オリエンタル酵母工業株式会社 | 新しい骨量増加薬 |
| CN102439026A (zh) * | 2008-05-13 | 2012-05-02 | A·R·舍拉尔 | 基于甾族惕告吉宁合成的苯甲酸腙的医学应用 |
| US10000503B2 (en) | 2011-09-09 | 2018-06-19 | Sumitomo Electric Industries, Ltd. | Power supply system and connector |
| WO2014062625A1 (en) | 2012-10-15 | 2014-04-24 | Iowa State University Research Foundation, Inc. | Tackifier compounds and methods of using the same |
| AU2014228017B2 (en) | 2013-03-15 | 2018-08-30 | Pharmatrophix, Inc. | Non-peptide BDNF Neurotrophin mimetics |
| JP2016516044A (ja) * | 2013-03-15 | 2016-06-02 | ファーマトロフィックス， インコーポレイテッド | 非ペプチドｂｄｎｆニューロトロフィン模倣化合物 |
| US9321803B2 (en) * | 2013-07-12 | 2016-04-26 | Children's Hospital Medical Center | Compositions and methods for inhibiting norovirus infection |
| EA201690938A1 (ru) | 2013-11-05 | 2016-11-30 | Бен-Гурион Юниверсити Оф Дзе Негев Рисерч Энд Дивелопмент Оторити | Соединения для лечения диабета и осложнений, возникающих из-за этого заболевания |
| US10077257B2 (en) | 2015-04-06 | 2018-09-18 | Iowa State University Research Foundation, Inc. | Aziridinated triglycerides and polymers formed therefrom |
| US10392471B2 (en) | 2015-05-14 | 2019-08-27 | Iowa State University Research Foundation, Inc. | Polymers and methods of making the same |
| WO2016186071A1 (ja) * | 2015-05-20 | 2016-11-24 | 国立大学法人大阪大学 | 炎症性サイトカイン分泌抑制活性を有するオリゴペプチド |
| WO2018182983A1 (en) | 2017-03-28 | 2018-10-04 | Children's Hospital Medical Center | Norovirus s particle based vaccines and methods of making and using same |
| CN110229118B (zh) | 2019-06-28 | 2021-03-02 | 深圳市三启药物开发有限公司 | 腙酰胺类衍生物及其在制备抗骨质疏松药物中的应用 |
| CN111686116B (zh) * | 2020-06-08 | 2021-05-04 | 广东省微生物研究所（广东省微生物分析检测中心） | 孕甾烷衍生物在制备破骨细胞分化抑制剂中的应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998028426A2 (en) * | 1996-12-23 | 1998-07-02 | Immunex Corporation | Ligand for receptor activator of nf-kappa b, ligand is member of tnf superfamily |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP1076699B1 (en) * | 1998-05-14 | 2008-10-29 | Immunex Corporation | Method of inhibiting osteoclast activity |
| EP2196930B1 (en) * | 1998-07-01 | 2011-03-23 | The Trustees of The University of Pennsylvania | Cavity induced allosteric modificatin of intermolecular interactions and methods of identifiying compounds that effect the same |
| HK1040261A1 (zh) * | 1998-09-15 | 2002-05-31 | 法麦克萨有限公司 | 负调节osteoprotegerin配体活性的方法 |
| AU777634B2 (en) * | 1999-07-28 | 2004-10-28 | Kazuhiro Aoki | Methods of inhibiting osteoclastogenesis |
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2000
- 2000-07-28 EP EP00950797A patent/EP1207873B1/en not_active Expired - Lifetime
- 2000-07-28 AU AU63846/00A patent/AU778190B2/en not_active Ceased
- 2000-07-28 DE DE60043346T patent/DE60043346D1/de not_active Expired - Lifetime
- 2000-07-28 WO PCT/US2000/020502 patent/WO2001008677A1/en not_active Ceased
- 2000-07-28 AT AT00950797T patent/ATE448781T1/de not_active IP Right Cessation
- 2000-07-28 JP JP2001513407A patent/JP4790179B2/ja not_active Expired - Fee Related
- 2000-07-28 CA CA002380007A patent/CA2380007A1/en not_active Abandoned
- 2000-07-28 CA CA002647796A patent/CA2647796A1/en not_active Abandoned
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998028426A2 (en) * | 1996-12-23 | 1998-07-02 | Immunex Corporation | Ligand for receptor activator of nf-kappa b, ligand is member of tnf superfamily |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001008677A1 (en) | 2001-02-08 |
| JP2003505503A (ja) | 2003-02-12 |
| AU6384600A (en) | 2001-02-19 |
| CA2380007A1 (en) | 2001-02-08 |
| AU2005200650B2 (en) | 2007-11-15 |
| EP1207873A4 (en) | 2006-04-12 |
| EP1207873A1 (en) | 2002-05-29 |
| EP1207873B1 (en) | 2009-11-18 |
| ATE448781T1 (de) | 2009-12-15 |
| AU2005200650A1 (en) | 2005-03-10 |
| AU778190B2 (en) | 2004-11-18 |
| CA2647796A1 (en) | 2001-02-08 |
| DE60043346D1 (de) | 2009-12-31 |
| WO2001008677A8 (en) | 2001-07-12 |
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