JP4772688B2 - メタドヘリンポリペプチドとそのコード核酸及び使用方法 - Google Patents
メタドヘリンポリペプチドとそのコード核酸及び使用方法 Download PDFInfo
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- JP4772688B2 JP4772688B2 JP2006539793A JP2006539793A JP4772688B2 JP 4772688 B2 JP4772688 B2 JP 4772688B2 JP 2006539793 A JP2006539793 A JP 2006539793A JP 2006539793 A JP2006539793 A JP 2006539793A JP 4772688 B2 JP4772688 B2 JP 4772688B2
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- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
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- A—HUMAN NECESSITIES
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
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- G—PHYSICS
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- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
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- Hematology (AREA)
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- Analytical Chemistry (AREA)
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- Microbiology (AREA)
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- Genetics & Genomics (AREA)
- Biophysics (AREA)
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- Optics & Photonics (AREA)
- Public Health (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51967503P | 2003-11-13 | 2003-11-13 | |
| US60/519,675 | 2003-11-13 | ||
| PCT/US2004/037471 WO2005050198A2 (en) | 2003-11-13 | 2004-11-10 | Metadherin polypeptides, encoding nucleic acids and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007514655A JP2007514655A (ja) | 2007-06-07 |
| JP2007514655A5 JP2007514655A5 (enExample) | 2007-12-27 |
| JP4772688B2 true JP4772688B2 (ja) | 2011-09-14 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006539793A Expired - Fee Related JP4772688B2 (ja) | 2003-11-13 | 2004-11-10 | メタドヘリンポリペプチドとそのコード核酸及び使用方法 |
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| Country | Link |
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| US (2) | US7560242B2 (enExample) |
| EP (1) | EP1695078A4 (enExample) |
| JP (1) | JP4772688B2 (enExample) |
| WO (1) | WO2005050198A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ547260A (en) * | 2003-11-12 | 2009-07-31 | Patrys Ltd | Methods of identifying neoplasm-specific antibodies and uses thereof |
| US7560242B2 (en) * | 2003-11-13 | 2009-07-14 | The Burnham Institute | Metadherin polypeptides, encoding nucleic acids and methods of use |
| DE102007017061A1 (de) | 2007-04-11 | 2008-10-16 | Voith Patent Gmbh | Verfahren zur Herstellung von Tissuepapier |
| US10745701B2 (en) | 2007-06-28 | 2020-08-18 | The Trustees Of Princeton University | Methods of identifying and treating poor-prognosis cancers |
| US20090324596A1 (en) | 2008-06-30 | 2009-12-31 | The Trustees Of Princeton University | Methods of identifying and treating poor-prognosis cancers |
| ES2645962T3 (es) | 2009-11-06 | 2017-12-11 | Hollister Incorporated | Película multicapa y producto de ostomía fabricado a partir de la misma |
| US9322051B2 (en) | 2013-10-07 | 2016-04-26 | General Electric Company | Probing of biological samples |
| US10357539B2 (en) | 2014-06-25 | 2019-07-23 | The Trustees Of Princeton University | Use of peptides that block metadherin-SND1 interaction as treatment for cancer |
| EP3791930A1 (en) * | 2019-09-13 | 2021-03-17 | Secarna Pharmaceuticals GmbH & Co. KG | Inhibitor of metadherin expression |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000056765A1 (en) * | 1999-03-19 | 2000-09-28 | Human Genome Sciences, Inc. | 48 human secreted proteins |
| WO2003077875A2 (en) * | 2002-03-15 | 2003-09-25 | Incyte Corporation | Proteins associated with growth, differentiation, and death |
| WO2004053075A2 (en) * | 2002-12-05 | 2004-06-24 | Diadexus, Inc. | Compositions, splice variants and methods relating to breast specific genes and proteins |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5496850A (en) | 1991-04-11 | 1996-03-05 | Toray Industries, Inc. | Antimetastasis agent of malignant tumors |
| US5965132A (en) * | 1992-03-05 | 1999-10-12 | Board Of Regents, The University Of Texas System | Methods and compositions for targeting the vasculature of solid tumors |
| US5552390A (en) | 1993-12-09 | 1996-09-03 | The Board Of Regents Of The University Of Nebraska | Phosphorothioate inhibitors of metastatic breast cancer |
| US6590076B1 (en) | 1999-04-02 | 2003-07-08 | Corixa Corporation | Compositions for the treatment and diagnosis of breast cancer and methods for their use |
| AU2003230665B2 (en) * | 2002-03-13 | 2010-02-18 | University Of Tennessee Research Foundation | Substituted tetrahydroisoquinoline compounds, methods of making, and their use |
| AU2003285490A1 (en) * | 2002-04-29 | 2004-03-03 | The Trustees Of Columbia University In The City Of New York | Astrocyte modulated genes and uses thereof |
| US7560242B2 (en) | 2003-11-13 | 2009-07-14 | The Burnham Institute | Metadherin polypeptides, encoding nucleic acids and methods of use |
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2004
- 2004-11-10 US US10/986,466 patent/US7560242B2/en not_active Expired - Fee Related
- 2004-11-10 WO PCT/US2004/037471 patent/WO2005050198A2/en not_active Ceased
- 2004-11-10 JP JP2006539793A patent/JP4772688B2/ja not_active Expired - Fee Related
- 2004-11-10 EP EP04816947A patent/EP1695078A4/en not_active Withdrawn
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2008
- 2008-12-16 US US12/336,409 patent/US8188051B2/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000056765A1 (en) * | 1999-03-19 | 2000-09-28 | Human Genome Sciences, Inc. | 48 human secreted proteins |
| WO2003077875A2 (en) * | 2002-03-15 | 2003-09-25 | Incyte Corporation | Proteins associated with growth, differentiation, and death |
| WO2004053075A2 (en) * | 2002-12-05 | 2004-06-24 | Diadexus, Inc. | Compositions, splice variants and methods relating to breast specific genes and proteins |
Also Published As
| Publication number | Publication date |
|---|---|
| US7560242B2 (en) | 2009-07-14 |
| JP2007514655A (ja) | 2007-06-07 |
| EP1695078A2 (en) | 2006-08-30 |
| US20090221718A1 (en) | 2009-09-03 |
| US20050208057A1 (en) | 2005-09-22 |
| EP1695078A4 (en) | 2007-07-11 |
| WO2005050198A3 (en) | 2005-07-07 |
| US8188051B2 (en) | 2012-05-29 |
| WO2005050198A2 (en) | 2005-06-02 |
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