JP4707321B2 - アンギオテンシンiiアゴニストとして有用な三環式化合物 - Google Patents
アンギオテンシンiiアゴニストとして有用な三環式化合物 Download PDFInfo
- Publication number
- JP4707321B2 JP4707321B2 JP2003500062A JP2003500062A JP4707321B2 JP 4707321 B2 JP4707321 B2 JP 4707321B2 JP 2003500062 A JP2003500062 A JP 2003500062A JP 2003500062 A JP2003500062 A JP 2003500062A JP 4707321 B2 JP4707321 B2 JP 4707321B2
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- sulfonamide
- ylmethylphenyl
- imidazol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 0 CC(*)*C(C)C(CC1(*)CCCCC1)C(N)=O Chemical compound CC(*)*C(C)C(CC1(*)CCCCC1)C(N)=O 0.000 description 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0113129.1 | 2001-05-31 | ||
GB0113129A GB0113129D0 (en) | 2001-05-31 | 2001-05-31 | Pharmaceutically-useful compounds |
GB0121611.8 | 2001-09-07 | ||
GB0121611A GB0121611D0 (en) | 2001-09-07 | 2001-09-07 | Pharmaceutically-useful-compounds |
US35095902P | 2002-01-25 | 2002-01-25 | |
US60/350,959 | 2002-01-25 | ||
GB0201794.5 | 2002-01-26 | ||
GB0201794A GB0201794D0 (en) | 2002-01-26 | 2002-01-26 | Pharmaceutically-useful compounds |
PCT/GB2002/002563 WO2002096883A1 (en) | 2001-05-31 | 2002-05-30 | Tricyclic compounds useful as angiotensin ii agonists |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2004533457A JP2004533457A (ja) | 2004-11-04 |
JP2004533457A5 JP2004533457A5 (ko) | 2006-01-05 |
JP4707321B2 true JP4707321B2 (ja) | 2011-06-22 |
Family
ID=32872450
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003500062A Expired - Lifetime JP4707321B2 (ja) | 2001-05-31 | 2002-05-30 | アンギオテンシンiiアゴニストとして有用な三環式化合物 |
Country Status (2)
Country | Link |
---|---|
JP (1) | JP4707321B2 (ko) |
KR (1) | KR100938817B1 (ko) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006109048A1 (en) * | 2005-04-12 | 2006-10-19 | Vicore Pharma Ab | New tricyclic angiotensin ii agonists |
AU2008264458B2 (en) * | 2007-06-20 | 2013-01-24 | Mitsubishi Tanabe Pharma Corporation | Novel malonic acid sulfonamide derivative and pharmaceutical use thereof |
RU2688163C2 (ru) * | 2013-03-15 | 2019-05-20 | Юниверсити Оф Саузерн Калифорния | Способы, соединения и композиции для лечения связанных с ангиотензином заболеваний |
EP3127554A4 (en) * | 2014-04-03 | 2017-12-06 | National Cerebral and Cardiovascular Center | Medicine for suppressing malignant tumor metastasis |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5444067A (en) * | 1993-08-30 | 1995-08-22 | Merck & Co., Inc. | Pharmaceutical treatment methods using angiotensin II receptor agonists bearing a thiophene moiety |
WO2000068226A1 (de) * | 1999-05-05 | 2000-11-16 | Aventis Pharma Deutschland Gmbh | 1-(p-thienylbenzyl)-imidazole als agonisten von angiotensin-(1-7)-rezeptoren, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische präparate |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5198438A (en) * | 1991-05-07 | 1993-03-30 | Merck & Co., Inc. | Angiotensin ii antagonists incorporating a substituted thiophene or furan |
-
2002
- 2002-05-30 JP JP2003500062A patent/JP4707321B2/ja not_active Expired - Lifetime
- 2002-05-30 KR KR1020037015757A patent/KR100938817B1/ko active IP Right Grant
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5444067A (en) * | 1993-08-30 | 1995-08-22 | Merck & Co., Inc. | Pharmaceutical treatment methods using angiotensin II receptor agonists bearing a thiophene moiety |
WO2000068226A1 (de) * | 1999-05-05 | 2000-11-16 | Aventis Pharma Deutschland Gmbh | 1-(p-thienylbenzyl)-imidazole als agonisten von angiotensin-(1-7)-rezeptoren, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische präparate |
Also Published As
Publication number | Publication date |
---|---|
KR100938817B1 (ko) | 2010-01-26 |
KR20040011519A (ko) | 2004-02-05 |
JP2004533457A (ja) | 2004-11-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US8124638B2 (en) | Tricyclic compounds useful as angiotensin II agonists | |
JP5625029B2 (ja) | 新規な三環系アンジオテンシンiiアゴニスト | |
AU2002257970A1 (en) | Tricyclic compounds useful as angiotensin II agonists | |
JP5718301B2 (ja) | 新規な三環系アンジオテンシンiiアゴニスト | |
WO2004046137A1 (en) | New tricyclic angiotensin ii agonists | |
WO2004085420A1 (en) | Bicyclic compounds useful as angiotensin ii agonists | |
JP2013067631A (ja) | 新規な二環式アンジオテンシンiiアゴニスト | |
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JP4707321B2 (ja) | アンギオテンシンiiアゴニストとして有用な三環式化合物 |
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