JP4707321B2 - アンギオテンシンｉｉアゴニストとして有用な三環式化合物 - Google Patents

アンギオテンシンｉｉアゴニストとして有用な三環式化合物 Download PDF

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Publication number
JP4707321B2
JP4707321B2 JP2003500062A JP2003500062A JP4707321B2 JP 4707321 B2 JP4707321 B2 JP 4707321B2 JP 2003500062 A JP2003500062 A JP 2003500062A JP 2003500062 A JP2003500062 A JP 2003500062A JP 4707321 B2 JP4707321 B2 JP 4707321B2
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JP
Japan
Prior art keywords
compound
formula
sulfonamide
ylmethylphenyl
imidazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2003500062A
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English (en)
Japanese (ja)
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JP2004533457A (ja
JP2004533457A5 (https=
Inventor
アンデルス・ハルベルグ
マティアス・アルテルマン
Original Assignee
ヴィコール・ファルマ・アーベー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0113129A external-priority patent/GB0113129D0/en
Priority claimed from GB0121611A external-priority patent/GB0121611D0/en
Priority claimed from GB0201794A external-priority patent/GB0201794D0/en
Application filed by ヴィコール・ファルマ・アーベー filed Critical ヴィコール・ファルマ・アーベー
Priority claimed from PCT/GB2002/002563 external-priority patent/WO2002096883A1/en
Publication of JP2004533457A publication Critical patent/JP2004533457A/ja
Publication of JP2004533457A5 publication Critical patent/JP2004533457A5/ja
Application granted granted Critical
Publication of JP4707321B2 publication Critical patent/JP4707321B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2003500062A 2001-05-31 2002-05-30 アンギオテンシンｉｉアゴニストとして有用な三環式化合物 Expired - Lifetime JP4707321B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
GB0113129A GB0113129D0 (en) 2001-05-31 2001-05-31 Pharmaceutically-useful compounds
GB0113129.1 2001-05-31
GB0121611.8 2001-09-07
GB0121611A GB0121611D0 (en) 2001-09-07 2001-09-07 Pharmaceutically-useful-compounds
US35095902P 2002-01-25 2002-01-25
US60/350,959 2002-01-25
GB0201794.5 2002-01-26
GB0201794A GB0201794D0 (en) 2002-01-26 2002-01-26 Pharmaceutically-useful compounds
PCT/GB2002/002563 WO2002096883A1 (en) 2001-05-31 2002-05-30 Tricyclic compounds useful as angiotensin ii agonists

Publications (3)

Publication Number Publication Date
JP2004533457A JP2004533457A (ja) 2004-11-04
JP2004533457A5 JP2004533457A5 (https=) 2006-01-05
JP4707321B2 true JP4707321B2 (ja) 2011-06-22

Family

ID=32872450

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003500062A Expired - Lifetime JP4707321B2 (ja) 2001-05-31 2002-05-30 アンギオテンシンｉｉアゴニストとして有用な三環式化合物

Country Status (2)

Country Link
JP (1) JP4707321B2 (https=)
KR (1) KR100938817B1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1869023T3 (da) * 2005-04-12 2012-04-10 Vicore Pharma Ab Nye tricykliske angiotensin-II-agonister
RU2462454C2 (ru) * 2007-06-20 2012-09-27 Мицубиси Танабе Фарма Корпорейшн Новое сульфонамидное производное малоновой кислоты и его фармацевтическое применение
EP3935944A1 (en) * 2013-03-15 2022-01-12 University Of Southern California, USC Stevens Compounds for the treatment of musculoskeletal diseases
JPWO2015152393A1 (ja) * 2014-04-03 2017-04-13 国立研究開発法人国立循環器病研究センター 悪性腫瘍転移抑制用医薬
GB201913603D0 (en) 2019-09-20 2019-11-06 Vicore Pharma Ab New compounds
CN115605265B (zh) * 2020-03-19 2026-01-23 维科尔药物公司 用于治疗和/或预防与血管紧张素ii相关的疾病、病症或病状的新型化合物
GB202007122D0 (en) * 2020-05-14 2020-07-01 Vicore Pharma Ab New process
GB202013721D0 (en) * 2020-09-01 2020-10-14 Vicore Pharma Ab New compounds
CA3212900A1 (en) * 2021-03-23 2022-09-29 Tomas Fex Selective angiotensin ii receptor ligands
GB202104038D0 (en) * 2021-03-23 2021-05-05 Vicore Pharma Ab New compounds
GB202104033D0 (en) * 2021-03-23 2021-05-05 Vicore Pharma Ab New compounds
KR20240035402A (ko) * 2021-07-09 2024-03-15 바이코어 파마 아베 신규의 선택적 안지오텐신 ii 화합물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198438A (en) * 1991-05-07 1993-03-30 Merck & Co., Inc. Angiotensin ii antagonists incorporating a substituted thiophene or furan
US5444067A (en) * 1993-08-30 1995-08-22 Merck & Co., Inc. Pharmaceutical treatment methods using angiotensin II receptor agonists bearing a thiophene moiety
YU78601A (sh) * 1999-05-05 2005-07-19 Aventis Pharma Deutschland Gmbh. 1-(p-tienilbenzil)-imidazoli kao agonisti angiotenzin-(1-7)- receptora, postupak za njihovu proizvodnju, njihova primena i farmaceutski preparati koji ih sadrže

Also Published As

Publication number Publication date
KR20040011519A (ko) 2004-02-05
JP2004533457A (ja) 2004-11-04
KR100938817B1 (ko) 2010-01-26

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