JP4707321B2 - アンギオテンシンｉｉアゴニストとして有用な三環式化合物 - Google Patents
アンギオテンシンｉｉアゴニストとして有用な三環式化合物 Download PDFInfo
- Publication number
- JP4707321B2 JP4707321B2 JP2003500062A JP2003500062A JP4707321B2 JP 4707321 B2 JP4707321 B2 JP 4707321B2 JP 2003500062 A JP2003500062 A JP 2003500062A JP 2003500062 A JP2003500062 A JP 2003500062A JP 4707321 B2 JP4707321 B2 JP 4707321B2
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- sulfonamide
- ylmethylphenyl
- imidazol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 0 CC(*)*C(C)C(CC1(*)CCCCC1)C(N)=O Chemical compound CC(*)*C(C)C(CC1(*)CCCCC1)C(N)=O 0.000 description 2
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0113129.1 | 2001-05-31 | ||
| GB0113129A GB0113129D0 (en) | 2001-05-31 | 2001-05-31 | Pharmaceutically-useful compounds |
| GB0121611A GB0121611D0 (en) | 2001-09-07 | 2001-09-07 | Pharmaceutically-useful-compounds |
| GB0121611.8 | 2001-09-07 | ||
| US35095902P | 2002-01-25 | 2002-01-25 | |
| US60/350,959 | 2002-01-25 | ||
| GB0201794A GB0201794D0 (en) | 2002-01-26 | 2002-01-26 | Pharmaceutically-useful compounds |
| GB0201794.5 | 2002-01-26 | ||
| PCT/GB2002/002563 WO2002096883A1 (en) | 2001-05-31 | 2002-05-30 | Tricyclic compounds useful as angiotensin ii agonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004533457A JP2004533457A (ja) | 2004-11-04 |
| JP2004533457A5 JP2004533457A5 (https=) | 2006-01-05 |
| JP4707321B2 true JP4707321B2 (ja) | 2011-06-22 |
Family
ID=32872450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003500062A Expired - Lifetime JP4707321B2 (ja) | 2001-05-31 | 2002-05-30 | アンギオテンシンｉｉアゴニストとして有用な三環式化合物 |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP4707321B2 (https=) |
| KR (1) | KR100938817B1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006235698B2 (en) * | 2005-04-12 | 2012-03-29 | Vicore Pharma Ab | New tricyclic angiotensin II agonists |
| US8461209B2 (en) * | 2007-06-20 | 2013-06-11 | Mitsubishi Tanabe Pharma Corporation | Malonic acid sulfonamide derivative and pharmaceutical use thereof |
| KR102230461B1 (ko) * | 2013-03-15 | 2021-03-22 | 유니버시티 오브 써던 캘리포니아 | 엔지오텐신-관련 질환들의 치료를 위한 방법들, 화합물들 및 조성물들 |
| US10071099B2 (en) | 2014-04-03 | 2018-09-11 | National Cerebral And Cardiovascular Center | Medicament for suppressing malignant tumor metastasis |
| GB201913603D0 (en) | 2019-09-20 | 2019-11-06 | Vicore Pharma Ab | New compounds |
| KR20230004501A (ko) * | 2020-03-19 | 2023-01-06 | 바이코어 파마 아베 | 안지오텐신 ⅱ와 관련된 질병, 장애, 또는 병태의 치료 및/또는 예방에 유용한 신규 화합물 |
| GB202007122D0 (en) * | 2020-05-14 | 2020-07-01 | Vicore Pharma Ab | New process |
| GB202013721D0 (en) * | 2020-09-01 | 2020-10-14 | Vicore Pharma Ab | New compounds |
| EP4313953A1 (en) * | 2021-03-23 | 2024-02-07 | Vicore Pharma AB | Selective angiotensin ii receptor ligands |
| GB202104033D0 (en) * | 2021-03-23 | 2021-05-05 | Vicore Pharma Ab | New compounds |
| GB202104038D0 (en) * | 2021-03-23 | 2021-05-05 | Vicore Pharma Ab | New compounds |
| MX2024000518A (es) * | 2021-07-09 | 2024-01-31 | Vicore Pharma Ab | Nuevos compuestos selectivos de angiotensina ii. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5198438A (en) * | 1991-05-07 | 1993-03-30 | Merck & Co., Inc. | Angiotensin ii antagonists incorporating a substituted thiophene or furan |
| US5444067A (en) * | 1993-08-30 | 1995-08-22 | Merck & Co., Inc. | Pharmaceutical treatment methods using angiotensin II receptor agonists bearing a thiophene moiety |
| YU78601A (sh) * | 1999-05-05 | 2005-07-19 | Aventis Pharma Deutschland Gmbh. | 1-(p-tienilbenzil)-imidazoli kao agonisti angiotenzin-(1-7)- receptora, postupak za njihovu proizvodnju, njihova primena i farmaceutski preparati koji ih sadrže |
-
2002
- 2002-05-30 KR KR1020037015757A patent/KR100938817B1/ko not_active Expired - Fee Related
- 2002-05-30 JP JP2003500062A patent/JP4707321B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| KR20040011519A (ko) | 2004-02-05 |
| KR100938817B1 (ko) | 2010-01-26 |
| JP2004533457A (ja) | 2004-11-04 |
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| JP5625029B2 (ja) | 新規な三環系アンジオテンシンｉｉアゴニスト | |
| AU2002257970A1 (en) | Tricyclic compounds useful as angiotensin II agonists | |
| JP5718301B2 (ja) | 新規な三環系アンジオテンシンｉｉアゴニスト | |
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| JP4707321B2 (ja) | アンギオテンシンｉｉアゴニストとして有用な三環式化合物 | |
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