JP4688293B2 - 神経活動の検出 - Google Patents

神経活動の検出 Download PDF

Info

Publication number
JP4688293B2
JP4688293B2 JP2000553803A JP2000553803A JP4688293B2 JP 4688293 B2 JP4688293 B2 JP 4688293B2 JP 2000553803 A JP2000553803 A JP 2000553803A JP 2000553803 A JP2000553803 A JP 2000553803A JP 4688293 B2 JP4688293 B2 JP 4688293B2
Authority
JP
Japan
Prior art keywords
pattern
calcium
organism
activity
neural
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2000553803A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002517754A (ja
JP2002517754A5 (enExample
Inventor
キム カイサー、
フィリップ ロゼー、
ジェイムズ ダグラス アームストロング、
Original Assignee
ユニヴァースティ コート オブ ザ ユニヴァースティ オブ グラスゴウ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ユニヴァースティ コート オブ ザ ユニヴァースティ オブ グラスゴウ filed Critical ユニヴァースティ コート オブ ザ ユニヴァースティ オブ グラスゴウ
Publication of JP2002517754A publication Critical patent/JP2002517754A/ja
Publication of JP2002517754A5 publication Critical patent/JP2002517754A5/ja
Application granted granted Critical
Publication of JP4688293B2 publication Critical patent/JP4688293B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5058—Neurological cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5085—Supracellular entities, e.g. tissue, organisms of invertebrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
    • G01N2333/43595—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from coelenteratae, e.g. medusae

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measuring Volume Flow (AREA)
JP2000553803A 1998-06-06 1999-06-07 神経活動の検出 Expired - Fee Related JP4688293B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9812127.0 1998-06-06
GBGB9812127.0A GB9812127D0 (en) 1998-06-06 1998-06-06 Detection of neural activity
PCT/GB1999/001786 WO1999064859A1 (en) 1998-06-06 1999-06-07 Detection of neural activity

Publications (3)

Publication Number Publication Date
JP2002517754A JP2002517754A (ja) 2002-06-18
JP2002517754A5 JP2002517754A5 (enExample) 2006-08-03
JP4688293B2 true JP4688293B2 (ja) 2011-05-25

Family

ID=10833277

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000553803A Expired - Fee Related JP4688293B2 (ja) 1998-06-06 1999-06-07 神経活動の検出

Country Status (7)

Country Link
US (1) US7038106B1 (enExample)
EP (1) EP1084406B1 (enExample)
JP (1) JP4688293B2 (enExample)
AT (1) ATE288586T1 (enExample)
DE (1) DE69923556T2 (enExample)
GB (1) GB9812127D0 (enExample)
WO (1) WO1999064859A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6489535B1 (en) 1999-03-18 2002-12-03 The Board Of Trustees Of The Leland Stanford Junior University Non-mammalian transgenic animal having an adult onset neurodegenerative phenotype
DK177327B1 (en) * 2011-12-23 2013-01-14 Entomopharm Aps OPTIMIZED INSECT BASED EX VIVO MODEL FOR EXAMINATION OF BLOOD BRAIN BARRIER penetration and method of exposing the insect brain to chemical compounds
WO2013138948A1 (en) * 2012-03-19 2013-09-26 Rugen Therapeutics R & D (Shanghai) Co., Ltd. Redox-sensitive calcium-sensor proteins and methods of use thereof
EP3254104B1 (en) * 2015-02-04 2021-08-25 Bristol-Myers Squibb Company Methods of selecting therapeutic molecules
PE20171766A1 (es) 2015-02-04 2017-12-21 Hoffmann La Roche Oligomeros antisentido de tau y usos de estos
CN106405029A (zh) * 2016-11-15 2017-02-15 融安县植保植检站 金桔附生绿球藻药剂筛选试验系统
WO2019241318A1 (en) * 2018-06-13 2019-12-19 Cornell University Bioluminescent markers of neural activity
CN114375390A (zh) * 2019-06-25 2022-04-19 分子装置有限公司 生物细胞振荡荧光分析

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3471793A (en) 1992-01-24 1993-09-01 Yale University Assay for neuro-excitatory agents
US5714666A (en) 1993-02-09 1998-02-03 Children's Hospital Of Philadelphia Measurement of intracellular calcium using bioluminescent apoaequorin expressed in mammalian cells
FR2727017B1 (fr) * 1994-11-21 1996-12-20 Sophie Feldblum Procede de criblage de facteurs sur modele de paralysie et methode d'obtention de ce modele
US5777195A (en) 1996-05-17 1998-07-07 The Rockefeller University Knockout mutant mouse for DARPP-32 and use thereof

Also Published As

Publication number Publication date
DE69923556T2 (de) 2006-01-26
ATE288586T1 (de) 2005-02-15
EP1084406B1 (en) 2005-02-02
JP2002517754A (ja) 2002-06-18
US7038106B1 (en) 2006-05-02
DE69923556D1 (de) 2005-03-10
GB9812127D0 (en) 1998-08-05
WO1999064859A1 (en) 1999-12-16
EP1084406A1 (en) 2001-03-21

Similar Documents

Publication Publication Date Title
Badre et al. The physiological and behavioral effects of carbon dioxide on Drosophila melanogaster larvae
Banks et al. The synaptic basis of GABAA, slow
Zhang et al. The transduction channel TRPM5 is gated by intracellular calcium in taste cells
White et al. Targeted attenuation of electrical activity in Drosophila using a genetically modified K+ channel
Luan et al. Functional dissection of a neuronal network required for cuticle tanning and wing expansion in Drosophila
Chen et al. Inwardly rectifying potassium (Kir) channels represent a critical ion conductance pathway in the nervous systems of insects
Dasari et al. Direct influence of serotonin on the larval heart of Drosophila melanogaster
Campusano et al. nAChR‐mediated calcium responses and plasticity in Drosophila Kenyon cells
JP4688293B2 (ja) 神経活動の検出
Jurzak et al. Characterization of vasopressin receptors in cultured cells derived from the region of rat brain circumventricular organs
Karunanithi et al. Using Drosophila to understand general anesthesia: from synapses to behavior
Collet Excitation-contraction coupling in skeletal muscle fibers from adult domestic honeybee
Papaefthimiou et al. An in vitro method for recording the electrical activity of the isolated heart of the adult Drosophila melanogaster
Norris et al. Recording central neurophysiological output from mosquito larvae for neuropharmacological and insecticide resistance studies
Wang et al. Whole cell calcium currents in acutely isolated olfactory bulb output neurons of the rat
Yang et al. Intrinsic membrane properties and cholinergic modulation of mouse basal forebrain glutamatergic neurons in vitro
Laursen et al. Heat and humidity sensors that alert mosquitoes to nearby human hosts
Jarriault et al. Perforated patch-clamp recording of mouse olfactory sensory neurons in intact neuroepithelium: functional analysis of neurons expressing an identified odorant receptor
Clark et al. Evidence for postsynaptic modulation of muscle contraction by a Drosophila neuropeptide
JP2010075057A (ja) 昆虫由来の電位依存性カリウムチャネル活性に関わる有害生物の生理状態に変化を与える薬剤
Momose-Sato et al. Optical identification of calcium-dependent action potentials transiently expressed in the embryonic rat brainstem
Stowers et al. The vomeronasal organ
Meech et al. Electrophysiology of ctenophore smooth muscle
Brockmann Implementation of a high throughput screening assay to identify and characterize insecticides acting on ion channels
Ammar et al. Immune tracheal intercellular signalling coordinates the muscle injury response in Drosophila

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060601

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20060601

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090609

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20090907

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20090914

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20091208

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100615

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100914

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100922

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20101214

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20110118

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20110215

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20140225

Year of fee payment: 3

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees