JP4683727B2 - 線維芽細胞様またはマクロファージ様細胞の形質導入のための手段と方法 - Google Patents

線維芽細胞様またはマクロファージ様細胞の形質導入のための手段と方法 Download PDF

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JP4683727B2
JP4683727B2 JP2000602796A JP2000602796A JP4683727B2 JP 4683727 B2 JP4683727 B2 JP 4683727B2 JP 2000602796 A JP2000602796 A JP 2000602796A JP 2000602796 A JP2000602796 A JP 2000602796A JP 4683727 B2 JP4683727 B2 JP 4683727B2
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フォヘルス、ロナルト
ヨハン スホウテン、ホフェルト
ボウト、アブラハム
ヤンス エムコ ハーフェンハ、メンゾ
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クルーセル ホランド ベスローテン フェンノートシャップ
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    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351Methods of production or purification of viral material
    • C12N2710/10352Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

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JP2000602796A 1999-03-04 2000-03-03 線維芽細胞様またはマクロファージ様細胞の形質導入のための手段と方法 Expired - Fee Related JP4683727B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99200624.7 1999-03-04
EP99200624 1999-03-04
PCT/NL2000/000133 WO2000052186A1 (en) 1999-03-04 2000-03-03 Means and methods for fibroblast-like or macrophage-like cell transduction

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JP2002537816A JP2002537816A (ja) 2002-11-12
JP2002537816A5 JP2002537816A5 (de) 2011-02-24
JP4683727B2 true JP4683727B2 (ja) 2011-05-18

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EP (1) EP1159438B1 (de)
JP (1) JP4683727B2 (de)
AT (1) ATE403006T1 (de)
AU (1) AU776067B2 (de)
CA (1) CA2364499C (de)
DE (1) DE60039683D1 (de)
WO (1) WO2000052186A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6929946B1 (en) 1998-11-20 2005-08-16 Crucell Holland B.V. Gene delivery vectors provided with a tissue tropism for smooth muscle cells, and/or endothelial cells
US6869936B1 (en) 1999-03-04 2005-03-22 Crucell Holland B.V. Means and methods for fibroblast-like or macrophage-like cell transduction
AU777041B2 (en) * 1999-05-17 2004-09-30 Crucell Holland B.V. Adenovirus derived gene delivery vehicles comprising at least one element of adenovirus type 35
US6492169B1 (en) 1999-05-18 2002-12-10 Crucell Holland, B.V. Complementing cell lines
EP1067188A1 (de) * 1999-07-08 2001-01-10 Introgene B.V. Infektion mit chimärischen Adenoviren der Zellen die für den Adenoviren Serotyp 5 Coxsacki Adenoviren Rezeptor (CAR) negativ sind
AU9434801A (en) * 2000-08-10 2002-02-18 Crucell Holland Bv Gene delivery vectors with cell type specificity for primary human chondrocytes
WO2002024730A2 (en) * 2000-09-20 2002-03-28 Crucell Holland B.V. Transduction of dendritic cells using adenoviral vectors
EP1195440A1 (de) * 2000-10-06 2002-04-10 Introgene B.V. Genverabreichung-Vektoren für Stammzellen
WO2002029073A2 (en) * 2000-10-06 2002-04-11 Crucell Holland B.V. Gene delivery vectors for stem cells
US6905678B2 (en) * 2001-07-07 2005-06-14 Crucell Holland B.V. Gene delivery vectors with cell type specificity for mesenchymal stem cells
EP1279738A1 (de) * 2001-07-06 2003-01-29 Crucell Holland B.V. Für mesenchymale Stammzellen spezifische Gen-Transfer-Vektoren
ATE405663T1 (de) 2002-04-25 2008-09-15 Crucell Holland Bv Stabile adenovirale vektoren und methoden für deren vermehrung
US20080153083A1 (en) 2003-10-23 2008-06-26 Crucell Holland B.V. Settings for recombinant adenoviral-based vaccines
EP1553983A2 (de) 2002-10-23 2005-07-20 Crucell Holland B.V. Einstellung für rekombinante adenovirus-basierte impfstoffe
WO2004055187A1 (en) 2002-12-17 2004-07-01 Crucell Holland B.V. Recombinant viral-based malaria vaccines
WO2014153204A1 (en) 2013-03-14 2014-09-25 Salk Institute For Biological Studies Oncolytic adenovirus compositions
EP3359175B1 (de) 2015-10-05 2020-09-16 Salk Institute for Biological Studies Synthetische adenoviren mit tropismus gegen geschädigtes gewebe zur förderung der wundheilung und geweberegeneration
JP7054527B2 (ja) 2016-02-23 2022-04-14 ソーク インスティテュート フォー バイオロジカル スタディーズ アデノウイルスの複製動態を測定するための高スループットアッセイ
KR20180112024A (ko) 2016-02-23 2018-10-11 더 솔크 인스티튜트 포 바이올로지칼 스터디즈 바이러스 동역학에 미치는 영향 최소화를 위한 치료용 아데노바이러스의 외인성 유전자 발현
CN110062630A (zh) 2016-12-12 2019-07-26 萨克生物研究学院 肿瘤靶向合成腺病毒及其用途
WO2018125970A1 (en) * 2016-12-30 2018-07-05 Salk Institute For Biological Studies Synthetic adenoviruses targeting bone tissue and uses thereof
WO2018218240A1 (en) 2017-05-26 2018-11-29 Epicentrx, Inc. Recombinant adenoviruses carrying transgenes

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997000326A1 (en) * 1995-06-15 1997-01-03 Introgene B.V. Packaging systems for human recombinant adenovirus to be used in gene therapy
JPH11500315A (ja) * 1995-02-21 1999-01-12 ジェンベク、インコーポレイティッド キメラアデノウイルスファイバータンパク質およびその使用方法
JP2000157289A (ja) * 1998-11-20 2000-06-13 Introgene Bv 平滑筋細胞および/または内皮細胞への組織向性を与えられた遺伝子送達ベクタ―

Family Cites Families (4)

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Publication number Priority date Publication date Assignee Title
FR2723697B1 (fr) * 1994-08-17 1996-09-20 Rhone Poulenc Rorer Sa Methode de traitement de la restenose par la therapie genique
ATE382694T1 (de) * 1995-11-28 2008-01-15 Genvec Inc Vektoren und methoden zum gentransfer in zellen
US20030017138A1 (en) * 1998-07-08 2003-01-23 Menzo Havenga Chimeric adenoviruses
EP1020529B1 (de) * 1998-11-20 2005-06-01 Crucell Holland B.V. Genverabreichende Vektoren mit Gewebetropismus für glatte Muskelzellen und/oder Endothelzellen

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11500315A (ja) * 1995-02-21 1999-01-12 ジェンベク、インコーポレイティッド キメラアデノウイルスファイバータンパク質およびその使用方法
WO1997000326A1 (en) * 1995-06-15 1997-01-03 Introgene B.V. Packaging systems for human recombinant adenovirus to be used in gene therapy
JP2000157289A (ja) * 1998-11-20 2000-06-13 Introgene Bv 平滑筋細胞および/または内皮細胞への組織向性を与えられた遺伝子送達ベクタ―

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CA2364499C (en) 2008-12-23
CA2364499A1 (en) 2000-09-08
DE60039683D1 (de) 2008-09-11
EP1159438B1 (de) 2008-07-30
JP2002537816A (ja) 2002-11-12
EP1159438A1 (de) 2001-12-05
AU2948800A (en) 2000-09-21
ATE403006T1 (de) 2008-08-15
WO2000052186A1 (en) 2000-09-08
AU776067B2 (en) 2004-08-26

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