JP4675566B2 - Inhaler - Google Patents

Description

  The present invention relates to an inhaler used for respiratory assistance or treatment.

  There are roughly three types of medical inhalers used clinically.

  They are a diffuser tube type Humidifferer, an atomizing / atomizing type ultrasonic nebulizer and a jet nebulizer using water droplet splitting by the Venturi effect. Both have a humidifying function and can be heated and inhaled by using a heater. Furthermore, it is connected to oxygen with a concentration of about 40% by volume and used for oxygen therapy.

  Further, it is humidified and used for respiratory assistance, or contains a drug and is used for treatment. Also, the purpose of use of these inhalers is classified into two types. One is to deposit drugs and water particles up to the trachea and bronchi, and the particle size of the droplets (water droplets) is 15 microns or more. The other one is for allowing the drug and water particles to further reach the alveoli, and the particle size of the droplet (water droplet) is 5 microns or less. Some of the latter are characterized by the use of ultrafine particles of 0.3 microns. In any case, a treatment device called a conventional nebulizer (a nebulizer) is a product considering only the size of a droplet (water droplet), that is, the particle diameter.

  On the other hand, when high energy is applied to water and it is split as water droplets, water undergoes ion dissociation (H +, OH-), and positive ions (positive air ions) and negative ions (negative air ions) are introduced into the air. generate.

  This phenomenon is well known as the Leonard effect (waterfall effect). Furthermore, the physiologically active action of these positive ions and negative ions is described as shown in Table 1 on page 77, published by Keiichi Morishita, “Water and Life”, published by Misato Ribo.

  In Table 1, positive ions refer to the case where the ratio of negative ions (n−) to positive ions (n +) (ion ratio; n− / n +) is 0.5 or less.

  When the ion ratio is 2 or more, it is called negative ion. And when the ion ratio is between 0.5 and 2, it is considered that positive ions and negative ions are substantially balanced.

  Thus, it has been known that small air ions have a physiological activity. However, there has been no example of improving the performance of the inhaler from the viewpoint of small air ions.

  Next, the structure of a conventional humidifier (hereinafter referred to as HD) and a jet nebulizer (hereinafter referred to as JN) using the venturi effect will be described with reference to FIGS. 7 and 8, respectively.

  As shown in FIG. 7, the HD 101 includes a water tank 102, an air diffuser 103, a supply pipe 104 communicating with the air diffuser 103, and an inlet 105. By providing the air diffuser 103, the supply air is humidified. The supply air is supplied from the supply port 106 of the HD 101, passes through the supply pipe 104, and is sent to the diffuser pipe 103 in the water tank 102. Since the air diffuser 103 is porous, the passing air tends to be fine bubbles. The air sent to the air diffuser 103 becomes fine bubbles and rises in the water tank 102. In this way, it is humidified and becomes humidified air, and is supplied from the suction port 105. Although not shown, if a heater is used in the HD 101, heated humidified air can be obtained. Next, JN will be described with reference to FIG.

  The same parts as those in FIG. 7 are denoted by the same reference numerals, and detailed description thereof is omitted. As shown in FIG. 8, the JN 107 using the Venturi effect includes a water tank 102, a supply pipe 104, and a suction pipe 108. The supply pipe 104 includes a supply port 106 and a nozzle 109 at the tip of the supply pipe 104, and has a structure in which a blower outlet 110 of the suction pipe 108 is provided in the vicinity of the nozzle 109 at the tip of the supply pipe 104.

  Inhalation air or high concentration oxygen for inhalation sent from the supply port 106 to the supply pipe 104 is blown out from a nozzle 109 at the tip of the supply pipe 104. At that time, the humidified humidified water or the therapeutic drug solution in the water tank 102 is sucked from the suction pipe 108 and sprayed from the outlet 110 by the negative pressure effect by the high-speed air flow, that is, the venturi effect. Supply air or high-concentration oxygen requires a high-speed air flow at the nozzle 109 and is used under pressure.

  The sprayed humidified water or chemical solution becomes sprayed water droplets, and is mixed with the suction air sent from the supply port 106 to the supply pipe 104 or the high concentration oxygen for suction by the spray mixing unit 111. Furthermore, it is mixed with room air sent from the room air suction port 112 and adjusted to an appropriate oxygen concentration, humidity, or an appropriate drug concentration. Next, it is sent to the suction port 105 and used for treatment or respiratory assistance.

  Since no water droplet separation mechanism is provided, water droplets of various sizes are contained and supplied. Although not shown, the heater is appropriately heated and supplied according to the use situation. In FIG. 8, a dotted line arrow shows the flow direction of water or a chemical | medical solution. A one-dot chain line arrow indicates the flow direction of the room air. An alternate long and two short dashes arrow indicates the flow direction of supply air or high-concentration oxygen. The solid line arrows indicate the flow direction of the mixed air and the adjusted air adjusted to an appropriate oxygen concentration, humidity, or an appropriate drug concentration. High concentration oxygen represents an oxygen concentration of about 40% by volume or more. The case where the oxygen concentration is about 98% to 100% by volume is also included. The indoor air may be supply air. The amount of air ions was measured for the above-described HD and JN and another conventional inhaler, an ultrasonic nebulizer. The measurement method of the positive ion amount (n +) and negative ion amount (n−) at the inlet of various inhalers is as follows. The measurement results are shown in Table 2.

  1. Comparison is made with room air.

  2. HD (see FIG. 7): Oxygen adjusted to a concentration of 50% by volume is blown into purified water heated by a heater at flow rates of 5, 10, and 15 (l / min). Then, each ion amount is measured by an ion tester at a position 10 cm away from the suction port.

  3. JN (see FIG. 8): Oxygen adjusted to a concentration of 35% by volume is supplied at flow rates of 5, 10, and 15 (l / min). Then, the amount of each ion is measured in the same manner as HD while sucking purified water in the container by the Venturi effect.

  4). Ultrasonic nebulizer: Purified water is put into a container on an ultrasonic vibrator, and oxygen adjusted to a concentration of 35% by volume is supplied at flow rates of 5, 10, and 15 (l / min). Then, the purified water is evaporated and the amount of each ion is measured in the same manner as HD.

Note that the ion tester used for the measurement has a mobility of 0.4 cm ² / V · s or more.

  Although the results are shown in Table 2, a steam humidifier heated by a heater or the like hardly generates air ions. That is, it is considered that there is almost no air ion action. On the other hand, JN and ultrasonic nebulizers generate a large amount of air ions, which is considered to be given high energy to water. However, the ion ratio is about 0.5, which is considered to be almost close to positive ions from the viewpoint of air ions.

  That is, in the conventional inhaler, a large amount of positive ions are generated compared to negative ions. This is because positive ions stimulate sympathetic nerves and have physiological effects such as vasoconstriction, as shown by the action of air ions in Table 1. An object of the present invention is to provide a compact inhaler that suppresses generation of positive ions, generates a large amount of negative ions compared to positive ions, and can perform water droplet separation with high performance.

  In addition, compactness is also required due to the nature of the product called an inhaler.

  However, if a water droplet separation mechanism that separates water droplets to suppress the generation of positive ions and generates a large amount of negative ions compared to positive ions is used, the entire apparatus becomes large and it is difficult to realize compactness. There is also a problem.

The fine water droplet generating means for generating fine water droplets and the fine water droplets containing negative ions and positive ions generated by the fine water droplet generating means are substantially separated so that the concentration of lactic acid in the arterial blood is lowered. A water droplet separating means that makes the number of ions twice or more, and a re-dividing and separating means for re-dividing and substantially separating the fine water droplets , wherein the re-dividing and separating means is a rotating network, A connected inhaler is provided.

The main body, the fine water droplet generator provided in the main body, and the downstream side of the fine water drop generator are provided so as to obtain an oxygen inhalation effect so that the lactic acid value concentration in the arterial blood is lowered. A separation unit, and a suction port provided downstream of the separation unit, wherein the fine water droplet generation unit is a water tank provided at a lower part of the main body, an ultrasonic vibrator provided at a lower part of the water tank, and the ultrasonic wave An ultrasonic circuit for driving a vibrator, generating fine water droplets by the ultrasonic vibrator and the ultrasonic circuit, sending air to the generated fine water droplets to form fine water droplet mixed air, and the separation The unit includes re-dividing and separating means for re-dividing and substantially separating fine water droplets from the fine water-drop mixed air, the re-dividing and separating means includes a wire mesh and a wire mesh rotating means for rotating the wire mesh , and negative ions derived from water More than twice the positive ion Unishi Te, a high humidity air containing a large amount of negative ions from the water introduced into the inlet, to provide an inhaler formed by connecting a high concentration of oxygen.

The present invention, by connecting the high-concentration oxygen at a high concentration of oxygen, provides an inhaler for supplying negative ions, a large amount of negative ions from the water broke the ion balance of the positive ions. Lactic acid level concentration in arterial blood is lowered, biological activity of living body is enhanced, high concentration oxygen inhalation time is short, or oxygen concentration effect is obtained at lower oxygen concentration, safer oxygen treatment A small inhaler capable of performing oxygen inhalation is provided.

  In examining the biologically active effect of negative ions on the living body due to water splitting, a preliminary test was first conducted to determine whether water-derived negative ions might enhance the biological activity of the living body. Preliminary test conditions are shown below. As a model for atopic dermatitis, chronic contact dermatitis is produced in the ears of mice. Next, exposure to negative ions generated from water and water splitting was performed to test the possibility of increased physiological activity of negative ions. The comparative test was conducted on a group exposed to negative ions generated by corona discharge (hereinafter referred to as an electric ion group) in addition to a group exposed to normal air (hereinafter referred to as a control group). A group exposed to negative ions generated from water and water splitting is hereinafter referred to as a true group.

  Temperature / humidity: 22 ° C. ± 1.5 ° C., 55% ± 10% RH, average negative ion amount is true group: 12,000 / cc, electric ion group: 30,000 / cc (however, this Only in the group, the ozone concentration is 3 to 10 ppb detection), and the control group is 0 / cc.

  The thickness of the earlobe that causes chronic contact dermatitis in the mouse ear and becomes thicker due to the lesion is measured. As a typical example, Table 3 (average value of n = 10) shows the start date (day 0) and the thickness (mm) of the earlobe after 14 days.

  As shown in Table 3, the true group (group exposed to water-derived negative ions) is a good result with a significant difference from the control group. In other words, it is suggested that water-derived negative ions may enhance physiological activity of the living body. That is, it has a beneficial effect on the living body. In addition, the electrical ion group (group exposed to negative ions generated by corona discharge) is worse than the control group, and this may be due to the influence of ozone. However, even with the same negative ion, it shows that the biologically active effect of the living body is different between the negative ion derived from water and water splitting and the negative ion generated by the discharge phenomenon (electric type) such as corona discharge. I think that the.

  Next, using water-derived negative ions generated by water splitting, which had the effect of enhancing the physiological activity of the living body in preliminary tests, the effect of reducing the lactic acid concentration in arterial blood, the physiological activity in vivo The enhancement was verified.

  The apparatus of the present invention is used as a negative ion supply source.

  The comparison was performed using a conventional JN (see FIG. 7).

  The experiment randomly divided 20 groups of neurosurgery patients with high lactate levels of 1.5 (mmol / l) or higher in arterial blood into two groups. The values measured during the experiment were such that the apparatus of the present invention had a negative ion amount of about 2,500 ions / cc, a positive ion amount of about 400 ions / cc, and an ion ratio (n− / n +) of 6.25. . The proportion of negative ions is very high. This device is called a “negative device”.

  On the other hand, the nebulizer had a negative ion amount of about 20,000 / cc, a positive ion amount of about 100,000 / cc, and an ion ratio (n− / n +) of 0.2. The proportion of positive ions was very high.

  This device is referred to as a “primary device”. Pour the oxygen concentration adjusted to 40% by volume into both devices, and inhale through the intake port according to the following procedure.

  One group (10 persons) inhales the first 4 hours from the negative device and the other 4 hours from the positive device. The other group (10 persons), on the contrary, inhales the first 4 hours from the positive device and the other 4 hours from the negative device. Table 4 shows the results measured every hour.

  As shown in Table 4, when 40% by volume of oxygen is inhaled for 4 hours together with negative ions derived from water using a negative device for the first time, the lactic acid level concentration in arterial blood begins to decrease. Next, after 4 hours, when switching to JN inhalation of the positive device and inhaling 40% concentration oxygen for 4 hours together with a large amount of positive ions, the lactate concentration in the arterial blood begins to rise. Conversely, when inhaling with the positive device for the first 4 hours and switching to the negative device after 4 hours and inhaling for 4 hours, in the inhalation of the positive device, the lactate concentration in the arterial blood was flat, Began to decline. Such a remarkable effect was not expected at all at first, and has been revealed for the first time by the present invention.

  This effect is not present in positive ions, and only negative ions derived from water are considered to enhance the physiological activity of the living body. The mechanism of the physiological activity enhancing action in vivo by negative ions derived from water is estimated as follows. It is considered that negative ions derived from water are absorbed into the body to eliminate active oxygen that inhibits aerobic metabolism in the living body and promotes oxidative phosphorylation, which is an ATP generation reaction.

The negative ions from the water to promote ATP production reaction in vivo, the concentration of oxygen inhaled lower, and in a short time an oxygen inhalation time, it is possible to reduce the lactate concentration in the arterial blood. In other words, oxygen treatment or respiratory assistance can be performed more safely. The water splitting or water droplet splitting referred to in the present invention is not intended for a steam humidifying inhaler heated by a heater or the like. This is a method in which water is ion-dissociated by applying a mechanical force expressed by water splitting or water droplet splitting to water and applying high energy to water.

  The mechanical force is a force that uses vibration energy such as an ultrasonic vibrator, a force that uses a venturi effect like JN, a nozzle type or other jet, a force that uses a collision, a rotating disk type, an impeller, etc. This is a force that uses injection, collision, and centrifugal force.

  Hereinafter, embodiments of the present invention will be described in more detail with reference to the drawings. In addition, the same number is attached | subjected about the same part as a prior art example, and detailed description is abbreviate | omitted.

(Embodiment 1)
As shown in FIG. 1, the main body 1 of the inhaler includes an ultrasonic vibrator 2 at the bottom, a water tank 102 containing water or a chemical solution, an atomization unit 3 provided at the top of the water tank, A blower 4 for blowing air to the gasification unit 3, a partition plate 5 having an opening 6 provided in the upper part of the atomization unit 3, a wire mesh 7 provided in the upper part of the partition plate 5, and the wire mesh are rotated. A wire mesh rotating motor 8 is provided. In addition, a suction port 105 is provided at the top of the main body 1 of the inhaler.

  In the above configuration, the water or chemical in the water tank 102 is sprayed and atomized by the ultrasonic vibrator 2 provided at the bottom of the water tank 102. The sprayed or atomized water or the fine water droplets of the chemical liquid is sent from the atomizing unit 3 to the partition plate 5 as air is sent by the blower 4 to form a fine water droplet mixed air. Relatively large water droplets are separated and removed by the baffle action, inertial separation action and the like of the partition plate 5, and then sent to the wire mesh 7 from the opening 6 of the partition plate. The wire mesh 7 is rotated by a wire mesh rotating motor 8. The water in the fine water droplet mixed air from which the relatively large water droplets have been removed by the partition plate 5 or the water droplets of the chemical solution cause re-division and re-aggregation of the water droplets due to the rotation of the wire mesh. And a fine water droplet is isolate | separated and a fine water droplet mixing air is made into a smaller ultra fine water droplet mixing air. By this ultrafine water droplet formation, positive ions charged in larger fine water droplets are separated. As a result, the ion balance ratio between positive ions and negative ions generated in substantially the same amount during water splitting is lost. The ion balance ratio at the suction port 105 is more than twice that of negative ions as compared to positive ions. The ultra-fine water droplet mixed air containing a large amount of generated negative ions and having a high humidity physiological activity is sent to the suction port 105 and used for breathing assistance or treatment.

  The partition plate 5 performs relatively large water droplet separation. However, combined with the fine water droplet separation by the rotation of the wire mesh 7, the water droplet separation is performed to such an extent that the ion balance is broken so that the negative ions are more than twice the positive ions. I can do it. Therefore, whether the partition plate 5 is one stage, two stages, two stages or more, or is not used is appropriately determined by design from the positive / negative ion ratio to be obtained, the air volume, and the like. It ’s fine. Next, apparatus specifications will be described below.

  Body size: diameter 105 × height 200 mm, partition plate: 2 pieces, partition plate opening diameter: 10 mm, wire mesh diameter: 98 mm, wire mesh pitch: 16-250 mesh, wire mesh rotation speed: 1,000-4 , 1,000 RPM, ultrasonic oscillation frequency of the ultrasonic transducer: 1.2 MHz. FIG. 2 is a plan view of the wire mesh 7. Oxygen adjusted to an oxygen concentration of 40% by volume with an oxygen concentration controller is introduced into this apparatus at flow rates (l / min) of 5, 10, and 15.

  Table 5 shows the measurement results with an ion tester and a thermohygrometer at a position 10 cm from the inlet.

  The supply of high-concentration oxygen to the inhaler is performed by connecting to oxygen having an oxygen concentration of 40% by volume adjusted by the oxygen concentration regulator.

  Further, depending on the patient's condition and treatment condition, it may be appropriately connected to a higher concentration of 40% to 100% high concentration oxygen. As equipment for supplying high-concentration oxygen, oxygen cylinders that supply 98% to 100% pure oxygen, oxygen generators that generate oxygen by chemical reaction or electrolysis of water, and separation of oxygen in the air by membrane separation There are oxygen concentrators that concentrate oxygen in the air by concentration or adsorption / desorption of gas molecules by zeolite or the like. The device is appropriately selected and used depending on the use conditions such as the oxygen concentration to be administered and the place of use. A device that supplies appropriately selected high-concentration oxygen is connected to an inhaler that generates negative ions by water splitting and water splitting, and is used for respiratory assistance or treatment. In addition, for the purpose of easy handling, an inhaler that generates negative ions from water and water splitting may be incorporated in a device that supplies high-concentration oxygen.

  In order to show the state of water droplet splitting and water droplet aggregation in the rotating wire mesh part, FIG. 3 shows the state of water droplet splitting and water droplet aggregation.

  FIG. 3 is a schematic diagram, and there is a possibility that the situation visually confirmed is not completely expressed. What is atomized by the ultrasonic vibrator is sent from the upper inflow port 9, and the wire mesh rotating motor 8 passes through the wire mesh 7 rotating via the shaft 10. The rotation of the wire mesh 7 causes re-dividing and agglomeration of the atomized fine water droplets and separation of the fine water droplets, resulting in ultra-fine water droplets. The upper region 11 of the wire mesh 7 into which fine water droplets from the atomization flow is innumerable and is opaque due to the atomization and fine water droplets.

  On the other hand, in the lower region 12 of the rotating wire mesh 7, fine water droplets are separated and removed and are transparent. The ultra fine water droplet mixed air after the fine water droplet separation is discharged from the outlet 13. FIG. 3 shows that the rotation of the wire mesh 7 causes water droplet re-division, water droplet aggregation, and separation of fine water droplets at the same time. As shown in FIG. 4, when a tube 14 is provided on the wire mesh 7 and the wire mesh 7 and the tube 14 are rotated by the wire mesh rotating motor 8, fine water droplets are efficiently separated. As a result, the ion balance between the generated negative ions and positive ions is lost, and a large amount of negative ions can be generated compared to positive ions.

(Embodiment 2)
The same parts as those in the conventional example and the first embodiment are denoted by the same reference numerals and detailed description thereof is omitted.

  As shown in FIG. 5, a cyclone separator 15 is provided above the atomizing portion 3 in the main body 1 of the inhaler.

  In the above configuration, the fine water droplet mixed air including the fine water droplets atomized by the ultrasonic vibrator 2 and the blower 4 is sent to the cyclone separator 15. The fine water droplet mixed air is sent from the cyclone inlet 16 into the cyclone separator 15 and becomes a swirl flow.

  Then, the fine water droplets are centrifuged, the ion balance between the positive ions and the negative ions is lost, and the ultra fine water droplet mixed air containing a large amount of negative ions is sent to the suction port 105 which is the cyclone outflow port 17. In this way, it is used for respiratory assistance or treatment.

  Here, the relationship between the ultrasonic oscillation frequency of the ultrasonic transducer and the generated negative ions was examined. In water splitting, an atomizing ultrasonic transducer (ultrasonic oscillation frequency: 1.2 MHz) and a cleaning ultrasonic transducer (ultrasonic oscillation frequency: 400 kHz) having different water particle diameters were used.

  The blower 4 sent air to the atomizing unit 3 in a swirling flow, and the wind speed was set to 1.0 m / sec and 2.5 m / sec. Table 6 shows the experimental results.

  In the case of the ultrasonic vibrator for atomization, the state of water droplets in the atomization unit 3 is about 3 microns in the central atomization particle diameter. Cloudy water droplets are also seen from the outlet 17 of the cyclone separator 15 in a state of being clouded from the atomizing section 3 into the cyclone separator 15. On the other hand, in the case of the cleaning ultrasonic vibrator, a water column of about 5 cm is formed at the center of the swirling flow of the atomizing section 3 and becomes steam from there. In addition, steam-like objects can no longer be seen at the outlet 17 of the cyclone separator 15. The experimental results with 100 kHz and 500 kHz ultrasonic transducers also gave almost the same ion ratio.

  The inhaler containing a large amount of negative ions targeted by the present invention can be obtained by adjusting the ultrasonic oscillation frequency region of the ultrasonic transducer to 100 kHz-500 kHz.

(Embodiment 3)
The same parts as those in the conventional example, the first embodiment, the second embodiment and the like are denoted by the same reference numerals, and detailed description thereof is omitted.

  As shown in FIG. 6, a wire mesh 7 and a wire mesh rotation motor 8 that rotates the wire mesh are provided at the subsequent stage of the spray mixing unit 111 in the main body 107 of the inhaler.

  In the above-described configuration, the fine water droplet mixed air including the fine water droplets mixed in the spray mixing unit 111 undergoes re-division of the atomized fine water droplets and separation into fine water droplets due to the rotation of the wire mesh 7, and the ultra fine water droplets Turn into. As a result, positively charged relatively large fine water droplets are separated and removed, the ion balance between positive ions and negative ions is lost, and a large amount of negative ions is generated. Then, it is sent to the suction port 105 and used for respiratory assistance or treatment. In this way, it is possible to provide a small inhaler that effectively generates negative ions.

The present invention, by connecting the high-concentration oxygen at a high concentration of oxygen, provides an inhaler for supplying negative ions, a large amount of negative ions from the water broke the ion balance of the positive ions. Lactic acid level concentration in arterial blood is lowered, biological activity of living body is enhanced, high concentration oxygen inhalation time is short, or oxygen concentration effect is obtained at lower oxygen concentration, safer oxygen treatment A small inhaler capable of performing oxygen inhalation is provided.

Sectional drawing of inhaler of Embodiment 1 of this invention The top view of the wire mesh of the inhaler of Embodiment 1 of this invention The figure which shows the condition of the water droplet separation of the inhaler of Embodiment 1 of this invention Sectional drawing which provided the pipe | tube in the wire mesh of the inhaler of Embodiment 1 of this invention Sectional drawing of the inhaler of Embodiment 2 of this invention Sectional drawing of the inhaler of Embodiment 3 of this invention Cross-sectional view showing a conventional inhaler HD Sectional drawing which shows JN which is a conventional inhaler

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Main body of inhaler 2 Ultrasonic vibrator 3 Atomization part 4 Blower 5 Partition plate 6 Opening 7 Wire mesh 8 Wire mesh rotation motor.
9 Inlet 10 Axis 11 Upper Region 12 Lower Region 13 Outlet 14 Tube 15 Cyclone Separator 16 Cyclone Inlet 17 Cyclone Outlet 101 Humidifier (HD)
102 Water tank 103 Aeration pipe 104 Supply pipe 105 Suction port 106 Supply port 107 Jet nebulizer (JN)
108 Suction Pipe 109 Nozzle 110 Blowout Port 111 Spray Mixing Unit 112 Indoor Air Suction Port

Claims (4)

The fine water droplet generating means for generating fine water droplets and the fine water droplets containing negative ions and positive ions generated by the fine water droplet generating means are substantially separated so that the concentration of lactic acid in the arterial blood is lowered. A water droplet separating means that makes the number of ions more than twice that of the ion, and a re-dividing and separating means for re-dividing and substantially separating the fine water droplets. An inhaler characterized by comprising: Inhaler according to claim 1, further comprising a cylinder in the rotary network. The fine water droplet generating means for generating fine water droplets and the fine water droplets containing negative ions and positive ions generated by the fine water droplet generating means are substantially separated so that the concentration of lactic acid in the arterial blood is lowered. Inhalation comprising: a water droplet separating means that makes the number of ions at least twice that of ions; the fine water droplet generating means is a jet nebulizer using a venturi effect; the water droplet separating means is a rotating net; and high concentration oxygen is connected vessel. A main body, a fine water droplet generator provided in the main body, a separator provided downstream of the fine water droplet generator, and a downstream of the separator so that the lactic acid concentration in arterial blood is reduced The fine water droplet generator has a water tank provided at the lower part of the main body, an ultrasonic vibrator provided at the lower part of the water tank, and an ultrasonic circuit for driving the ultrasonic vibrator. A blower means for generating fine water droplets by the ultrasonic vibrator and the ultrasonic circuit, sending air into the generated fine water droplets to form fine water droplet mixed air, and the separating unit from the fine water droplet mixed air. Re-split separation means for re-dividing and substantially separating water droplets, the re-split separation means comprises a wire mesh and a wire mesh rotation means for rotating the wire mesh, so that negative ions are more than twice the positive ions, High humidity with a lot of negative ions Inhaler introducing air into said inlet, formed by connecting a high concentration of oxygen.

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