CN111494760A - Plasma active water atomizer - Google Patents

Plasma active water atomizer Download PDF

Info

Publication number
CN111494760A
CN111494760A CN202010293519.9A CN202010293519A CN111494760A CN 111494760 A CN111494760 A CN 111494760A CN 202010293519 A CN202010293519 A CN 202010293519A CN 111494760 A CN111494760 A CN 111494760A
Authority
CN
China
Prior art keywords
plasma
activation
pump
mixed solution
air pump
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202010293519.9A
Other languages
Chinese (zh)
Inventor
刘定新
王小华
荣命哲
王子丰
陈锦坤
张敬业
范成瑜
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xian Jiaotong University
Original Assignee
Xian Jiaotong University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xian Jiaotong University filed Critical Xian Jiaotong University
Priority to CN202010293519.9A priority Critical patent/CN111494760A/en
Publication of CN111494760A publication Critical patent/CN111494760A/en
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001Particle size control
    • A61M11/003Particle size control by passing the aerosol trough sieves or filters
    • CCHEMISTRY; METALLURGY
    • C02TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02FTREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00Treatment of water, waste water, or sewage
    • C02F1/30Treatment of water, waste water, or sewage by irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • A61M2205/3334Measuring or controlling the flow rate

Abstract

The plasma active water atomizer is disclosed, wherein an activation cavity contains an aqueous solution to be activated, gas is conveyed into a plasma generator through an activation gas pump to generate plasma active particles, and the plasma active particles are introduced into the activation cavity under the action of the activation gas pump to generate plasma active water with the aqueous solution; the mixing pump is communicated with a liquid medicine pool containing liquid medicine and the activation cavity through a water outlet, and the mixing pump forms mixed solution by the plasma active water and the liquid medicine according to a preset proportion to pump the mixed solution into the atomizing cup; the control unit controls the activation air pump to generate plasma active water with a preset volume, controls the mixing pump to generate a mixed solution with a preset concentration and controls the atomization air pump to pump out the mixed solution fog particles at a preset speed.

Description

Plasma active water atomizer
Technical Field
The invention relates to the technical field of atmospheric pressure cold plasmas, in particular to a plasma active water atomizer.
Background
Respiratory diseases are the most common diseases with the highest fatality rate and heavy economic burden in recent years. The aerosol inhalation therapy is a method for treating respiratory system diseases such as bronchial asthma, acute laryngotracheobronchitis, chronic obstructive pulmonary disease and the like by atomizing a medicinal solution into tiny particles by using a special atomizing device and inhaling the tiny particles into nasopharynx, larynx, respiratory tract and lung to deposit the medicament on a focus to treat the diseases. The liquid medicine selected by the aerosol inhalation therapy comprises inhalation hormone, antibiotics, bronchodilators, phlegm-resolving medicines and the like, and can effectively diminish inflammation, relieve cough, contact bronchospasm, humidify air passages, promote sputum excretion, smoothen air passages and improve ventilation function. However, some inhaled hormones can destroy the immune function of the oral mucosa, and easily cause the infection of candida oralis. Meanwhile, when the sputum is excessively humidified and cannot be timely absorbed or discharged from the body by the respiratory tract mucosa, the sputum is beneficial to the propagation of pathogenic microorganisms to cause aggravation of infection on one hand, and on the other hand, the sputum flows downwards along the body position to promote downward extension of the infection. In addition, the aerosol inhalation therapy has many side effects such as acute pulmonary edema and asphyxia. Therefore, it is necessary to overcome the side effects of aerosol inhalation therapy and find a proper mixed liquid medicine for treatment.
The above information disclosed in the background section is only for enhancement of understanding of the background of the invention and therefore it may contain information that does not form the prior art that is well known to those of ordinary skill in the art.
Disclosure of Invention
In view of the above problems, an object of the present invention is to provide a plasma activated water atomizer which stably generates atmospheric pressure cold plasma and generates plasma activated water, and mixes the plasma activated water with a specific chemical solution and atomizes the mixture into mist particles of the chemical solution having a specific diameter by an atomizing device, so as to overcome the above drawbacks of the prior art. Is expected to be inhaled by a patient for treatment, solves the defect problem of aerosol inhalation treatment and ensures that the treatment effect is optimal. .
The purpose of the invention is realized by the following technical scheme.
A plasma-activated water atomizer comprising,
an activation chamber containing an aqueous solution to be activated, the activation chamber comprising a filler and a water outlet;
the plasma generator is powered by a high-voltage power supply, one end of the plasma generator is communicated with the activation air pump, the other end of the plasma generator is communicated with the activation cavity, air is input into the plasma generator through the activation air pump to generate plasma active particles, and the plasma active particles are introduced into the activation cavity under the action of the activation air pump to generate plasma active water with the aqueous solution;
the mixing pump is communicated with a liquid medicine pool containing liquid medicine and the activation cavity through a water outlet, and the mixing pump forms mixed solution by the plasma active water and the liquid medicine according to a preset proportion to pump the mixed solution into the atomizing cup;
an atomizing cup connected to the mixing pump to receive the mixed solution,
an atomizing device for atomizing the mixed solution in the atomizing cup to form mixed solution fog particles with a predetermined size,
the atomizing air pump is used for pumping out the mixed solution fog particles formed by the atomizing device;
the control unit is connected with the high-voltage power supply, the activation air pump, the atomization air pump and the mixing pump, and sends out a control instruction based on the instruction, controls the high-voltage power supply to provide preset electric energy for the plasma generator to generate plasma active particles, controls the activation air pump to generate plasma active water with a preset volume, controls the mixing pump to generate a mixed solution with a preset concentration and controls the atomization air pump to pump out the mixed solution fog particles at a preset speed.
In the plasma active water atomizer, the control unit is further connected with the atomizing device, the control unit sends an instruction to the atomizing device, and the atomizing device generates mixed solution fog particles based on the instruction.
In the plasma active water atomizer, the activation cavity further comprises an air outlet, and the air outlet is communicated with the activation air pump through a balance air valve.
In the plasma active water atomizer, a control unit is a single chip microcomputer, a digital signal processor, an Application Specific Integrated Circuit (ASIC) or a Field Programmable Gate Array (FPGA), the control unit comprises a memory and a timer, and the memory comprises one or more Read Only Memories (ROM), a Random Access Memory (RAM), a flash memory or an Electrically Erasable Programmable Read Only Memory (EEPROM).
The plasma active water atomizer is characterized by further comprising a voltage sensor for measuring the voltage of a high-voltage power supply, a flow velocity sensor for measuring the velocity of fog particles of a discharged mixed solution and an alarm unit, wherein the control unit is connected with the voltage sensor, the flow velocity sensor and the alarm unit and responds to the situation that the voltage or the flow velocity exceeds a preset range, and the control unit sends an alarm instruction to the alarm unit.
In the plasma active water atomizer, the plasma generator comprises a central copper core configured into a high-voltage electrode, an inner-layer glass tube and an outer-layer glass tube are sleeved outside the central copper core, the outer-layer glass tube is connected with a ground electrode, and gas input by the activation gas pump flows through a gas channel between the inner-layer glass tube and the outer-layer glass tube to generate atmospheric pressure cold plasma.
In the plasma active water atomizer, a high-voltage power supply is a sine high-voltage power supply, the output voltage is 6kV, the output frequency is 15kHz, and 220V alternating current is used as the input of the high-voltage power supply.
In the plasma active water atomizer, the diameter of the mixed solution fog particles is controlled by the atomization device through setting the oscillation frequency or the mesh with the preset diameter, and the diameter of the mixed solution fog particles is not more than 5 micrometers.
In the plasma active water atomizer, the atomization mode of the atomization device comprises ultrasonic atomization, compression type atomization or micro-grid type atomization.
In the plasma active water atomizer, the discharge mode of the plasma generator comprises dielectric barrier discharge, jet discharge, corona discharge or sliding arc discharge, and the aqueous solution comprises normal saline or medical purified water.
The aqueous solution of the atmospheric pressure cold plasma treatment has a sterilizing ability, and such an aqueous solution is called plasma active water.
Compared with the prior art, the invention has the beneficial effects that:
the invention uses the plasma active water for atomization sterilization alone, and can also use the plasma active water and the liquid medicine together, thereby being hopeful to improve the anti-infection ability of the atomized liquid medicine entering the respiratory tract. And the mixing proportion of the liquid medicine and the plasma active water can be controlled to be adjustable so as to adapt to the concentration of different mixed liquid medicines. At the same time, the device should be able to control the size of the mist particles and the discharge speed of the water mist. Compared with the existing treatment methods such as lavage and injection, the plasma active water atomizer can atomize the plasma active water into fine fog particles, is expected to reach the parts which cannot be contacted by the existing treatment methods, such as deep breathing systems, and is in direct contact with focuses, and has the advantages of quick response and good effect. Because the plasma active water has high-efficiency sterilization and anti-infection performance, the plasma active water is added into the device, and the problem of side effects of mucosa candida infection, excessive humidification infection and the like in the atomization therapy can be solved. The device has excellent compatibility and safety, can independently atomize liquid medicine and plasma active water, and can atomize mixed solution of the liquid medicine and the plasma active water when needed; the speed of the water mist discharged by the atomizing device is adjustable, the size of mist particles is not more than 5 microns, and the optimal treatment effect is expected to be achieved.
Plasma active aqueous solution (physiological saline, high dilution H)2O2) As experimental group, medical hydrogen peroxide and chlorhexidine solution are used as control group. As can be seen from the experimental results, the plasma active aqueous solution (physiological saline, high dilution H)2O2) The killing effect on staphylococcus aureus exceeds that of medical hydrogen peroxide and chlorhexidine solution by more than 3 orders of magnitude. This indicates that the plasma-active aqueous solution has a stronger killing power of pathogens than the conventional antibacterial agent. In addition, the article of Shock in the authoritative journal of the field of intensive care shows that the plasma active water has the function of treating sepsisThe treatment effect increased the 5-day survival rate of mice in the sepsis model by 7-fold, as shown in figure 2. Sepsis refers to systemic inflammatory response syndrome caused by infection, and plasma active water can reduce the number of pathogens in mice and reduce cell apoptosis, so that the survival rate of sepsis model mice is finally improved, which indirectly indicates that the plasma active water solution can efficiently kill the pathogens, is safe and non-toxic to human bodies, has no stimulation to human tissues such as respiratory tracts and the like, and does not cause adverse reactions.
The above description is only an overview of the technical solutions of the present invention, and in order to make the technical means of the present invention more clearly apparent, and to make the implementation of the content of the description possible for those skilled in the art, and to make the above and other objects, features and advantages of the present invention more obvious, the following description is given by way of example of the specific embodiments of the present invention.
Drawings
Various other advantages and benefits of the present invention will become apparent to those of ordinary skill in the art upon reading the following detailed description of the preferred embodiments. The drawings are only for purposes of illustrating the preferred embodiments and are not to be construed as limiting the invention. It is obvious that the drawings described below are only some embodiments of the invention, and that for a person skilled in the art, other drawings can be derived from them without inventive effort. Also, like parts are designated by like reference numerals throughout the drawings.
In the drawings:
fig. 1 is a comparative graph illustrating the sterilization effect of plasma-activated water according to an embodiment of the present invention;
FIG. 2 is a graph showing the survival rate of plasmonic active water for a mouse sepsis treatment according to one embodiment of the invention;
FIG. 3 is a block diagram of the structure of an embodiment of a plasma activated water atomizer according to the present invention;
fig. 4 is a schematic structural diagram of a plasma generator in an embodiment of the plasma activated water atomizer according to the present invention.
The invention is further explained below with reference to the figures and examples.
Detailed Description
Specific embodiments of the present invention will be described in more detail below with reference to fig. 1 to 4. While specific embodiments of the invention are shown in the drawings, it should be understood that the invention may be embodied in various forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art.
It should be noted that certain terms are used throughout the description and claims to refer to particular components. As one skilled in the art will appreciate, various names may be used to refer to a component. This specification and claims do not intend to distinguish between components that differ in name but not function. In the following description and in the claims, the terms "include" and "comprise" are used in an open-ended fashion, and thus should be interpreted to mean "include, but not limited to. The description which follows is a preferred embodiment of the invention, but is made for the purpose of illustrating the general principles of the invention and not for the purpose of limiting the scope of the invention. The scope of the present invention is defined by the appended claims.
For the purpose of facilitating understanding of the embodiments of the present invention, the following description will be made by taking specific embodiments as examples with reference to the accompanying drawings, and the drawings are not to be construed as limiting the embodiments of the present invention.
For better understanding, as shown in fig. 3, a plasma activated water atomizer includes,
an activation chamber 131 containing an aqueous solution to be activated, the activation chamber 131 comprising a filler and a water outlet;
the plasma generator 121 is powered by a high-voltage power supply 122, one end of the plasma generator 121 is communicated with the activation air pump 111, the other end of the plasma generator 121 is communicated with the activation cavity 131, air is input into the plasma generator 121 through the activation air pump 111 to generate plasma active particles, and the plasma active particles are introduced into the activation cavity 131 under the action of the activation air pump 111 to generate plasma active water with the aqueous solution;
the mixing pump 141 is communicated with a liquid medicine pool 133 containing liquid medicine and the activation cavity 131 through a water outlet, and the mixing pump 141 forms mixed solution of the plasma active water and the liquid medicine according to a preset proportion to pump the mixed solution into the atomizing cup 152;
an atomizing cup 151 connected to the mixing pump 141 to receive the mixed solution;
an atomizing device 152 for atomizing the mixed solution in the atomizing cup 151 to form mist particles of the mixed solution of a predetermined size;
an atomizing air pump 161 that pumps out the mist of the mixed solution formed by the atomizing device 152;
and a control unit 171 connected to the high voltage power supply 122, the activation air pump 111, the atomization air pump 161 and the mixing pump 141, wherein the control unit 171 issues a control instruction based on the instruction, controls the high voltage power supply 122 to supply a predetermined electric power to the plasma generator 121 to generate plasma active particles, controls the mixing pump 141 to generate a mixed solution with a predetermined concentration, and controls the atomization air pump 161 to pump out the mixed solution fog particles at a predetermined rate.
In the preferred embodiment of the plasma activated water atomizer, the control unit 171 is further connected to the atomization device 152, the control unit 171 sends a command to the atomization device 152, and the atomization device 152 generates the mist of the mixed solution based on the command.
In the preferred embodiment of the plasma-activated water atomizer, the activation chamber 131 further comprises an air outlet, and the air outlet is communicated with the activation air pump 111 through a balance air valve 132.
In a preferred embodiment of the plasma activated water atomizer, the control unit 171 is a single chip microcomputer, a digital signal processor, an application specific integrated circuit ASIC or a field programmable gate array FPGA, and the control unit 171 includes a memory and a timer, and the memory includes one or more of a read only memory ROM, a random access memory RAM, a flash memory or an electrically erasable programmable read only memory EEPROM.
In a preferred embodiment of the plasma activated water atomizer, the plasma activated water atomizer further comprises a voltage sensor for measuring the voltage of the high voltage power supply 122, a flow rate sensor for measuring the speed of the mist of the discharged mixed solution, and an alarm unit, wherein the control unit 171 is connected to the voltage sensor, the flow rate sensor, and the alarm unit, and in response to the voltage or the flow rate exceeding a predetermined range, the control unit 171 sends an alarm instruction to the alarm unit.
In the preferred embodiment of the plasma active water atomizer, the plasma generator 121 comprises a central copper core configured as a high voltage copper electrode 211, an inner glass tube 213 and an outer glass tube 214 are sleeved outside the central copper core, the outer glass tube 214 is connected with the ground electrode 212, and the gas input through the activation gas pump 111 flows through a gas channel 215 between the inner glass tube 213 and the outer glass tube 214 to generate the atmospheric pressure cold plasma.
In the preferred embodiment of the plasma activated water atomizer, the high voltage power supply 122 is a sinusoidal high voltage power supply 122, the output voltage is 6kV, the output frequency is 15kHz, and 220V ac is used as the input of the high voltage power supply 122.
In the preferred embodiment of the plasma activated water atomizer, the atomizing means 152 controls the diameter of the mist of the mixed solution, which is not more than 5 μm, by setting the oscillation frequency or the mesh of a predetermined diameter.
In a preferred embodiment of the plasma activated water atomizer, the atomization mode of the atomization device 152 includes ultrasonic atomization, compression atomization or micro-grid atomization.
In the preferred embodiment of the plasma activated water atomizer, the discharge mode of the plasma generator 121 includes dielectric barrier discharge, jet discharge, corona discharge or sliding arc discharge.
The aqueous solution includes physiological saline or medical purified water.
In a preferred embodiment of the plasma activated water atomizer, a plasma activated water atomizer comprises:
the plasma generator 121 is powered by a high-voltage power supply 122, one end of the plasma generator 121 is communicated with the activation air pump 111, the other end of the plasma generator 121 is communicated with the activation cavity 131, and the plasma generator can stably discharge in the introduced gas to generate plasma;
an activation gas pump 111 for introducing gas into the plasma generator 121 and introducing plasma active particles generated by the discharge of the plasma generator 121 into the activation chamber 131;
the activation cavity 131 is a place where the plasma gas-phase active particles react with the aqueous solution to generate plasma active water;
a mixing pump 141 for feeding the plasma active water and the chemical liquid into the atomizing cup 151 in a certain ratio;
an atomizing cup 151 for holding a solution to be atomized;
an atomizing device 152 for atomizing the solution to be atomized into a water mist for inhalation therapy;
an atomizing air pump 161 for blowing out the mist particles generated by the atomizing device 152 and inhaling the mist particles by the patient;
the control unit 171 has one end connected to the high-voltage power supply 122 and the activation air pump 111, and the other end connected to the atomizing air pump 161, the mixing pump 141, and the atomizing device 152.
The plasma generator 121 generates atmospheric pressure cold plasma through high-voltage discharge, introduces the atmospheric pressure cold plasma into an aqueous solution for activation treatment, introduces plasma active water and a liquid medicine into the atomizing cup 151 through the mixing pump 141 according to a certain proportion, atomizes the solution in the atomizing cup 151 into water mist through the atomizing device 152, and finally outputs the water mist containing the plasma active particles, so that bacteria and viruses can be inhibited.
In the preferred embodiment of the plasma activated water atomizer, the plasma gas-phase active particles generated in the plasma generator 121 are introduced into the activation chamber 131 filled with the aqueous solution under the blowing action of the activation air pump 111 to perform the activation treatment on the aqueous solution. The activation cavity 131, the liquid medicine pool 133 and the atomizing cup 151 are connected through the mixing pump 141, the plasma active water in the activation cavity 131 and the liquid medicine in the liquid medicine pool 133 are mixed in a certain proportion through the mixing pump 141 and are introduced into the atomizing cup 151, and the atomizing device 152 can atomize the plasma active water, the liquid medicine or the mixed solution of the plasma active water and the liquid medicine in the atomizing cup 151 into micro mist particles and discharge the micro mist particles through a water mist outlet.
In the preferred embodiment of the plasma activated water atomizer, the plasma generator 121 may use the activation gas pump 111 to introduce air, helium, argon, or other gases, and generate stable plasma in these gases by high voltage discharge. The tail gas in the activation chamber 131 is connected to the activation air pump 111 through the balancing air valve 132, and the balancing air pump is used for ensuring that the atmospheric pressure in the air path is equal to the external atmospheric pressure. The air introduced by the atomizing air pump 161 is air, the flow rate of the atomizing air pump 161 can be controlled, the water mist discharging speed can be controlled, and the air supply mode of the device can be air pump air supply or air bottle air supply.
In the preferred embodiment of the plasma activated water atomizer, the plasma generator 121 is powered by a pulse, sine or dc high voltage power supply 122, and the discharge mode can be selected from dielectric barrier discharge, corona discharge, sliding arc discharge and other discharge forms.
In the preferred embodiment of the plasma activated water atomizer, one end of the control unit 171 is connected to the high voltage power supply 122 and the activation air pump 111, and the other end is connected to the atomization air pump 161, the mixing pump 141 and the atomization device 152. The device can be provided with a switch power-off protection module, the work and the shutdown of the control device are controlled, when a fault occurs, the system is powered off, the device stops working, and the information of the on/off state, the voltage, the fault and the like of each pump can be observed in real time through the display screen.
In a preferred embodiment of the plasma-activated water atomizer, the means for fault handling of the device comprises: when the voltage and the current of the high-voltage power supply 122 are abnormal or the discharge of the plasma generator 121 is abnormal, the device emergently stops working and starts alarming; when the water mist discharge rate of the device is too fast or too slow, the control unit 171 controls the atomizing air pump 161 to supply air into the atomizing device 152 at a stable rate by adjusting the working voltage of the atomizing air pump 161.
To further understand the present invention, in one embodiment, a plasma activated water atomizer includes an activation air pump 111, a plasma generator 121, a high voltage power supply 122, an activation chamber 131, a balance air valve 132, a drug solution reservoir 133, a mixing pump 141, an atomizing cup 151, an atomizing device 152, an atomizing air pump 161, and a control unit 171.
An activation gas pump 111 is connected to the plasma generator 121 for blowing gas into the plasma generator and ultimately into the activation chamber 131; the plasma generator 121 is used for preparing atmospheric pressure cold plasma, a reaction electrode thereof is connected with a high-voltage power supply, and generated plasma active particles are introduced into the activation cavity. The activation chamber 131 is a place where plasma active particles react with an aqueous solution to generate plasma active water, and comprises a water filling port, an air outlet and a water outlet. The water filling port is used for filling water solution into the activation cavity 131, and the water outlet is connected with the mixing pump 141. The air outlet is connected with the activation air pump 111 through a balance air valve 132, and the balance air valve 132 is used for ensuring the balance of the air path and the external air pressure
The liquid medicine tank 133 is used to contain liquid medicine. The mixing pump 141 is respectively communicated with the liquid medicine pool 133, the activation cavity 131 and the atomizing cup 151, and is used for separately introducing the liquid medicine or the plasma activated water or the mixed solution of the two into the atomizing cup 151. The atomizing cup 151 is a place for containing and atomizing the solution to be atomized, and the atomizing device 151 atomizes the solution into mixed solution mist particles with a specified size under the control of the control unit 171, and the mixed solution mist particles are discharged from a water mist outlet under the blowing action of the gas introduced into the atomizing air pump 161. The control unit 171 is powered by a 220V to 12V dc power supply, one end of which is connected to the high voltage power supply and the activation air pump, and the other end of which is connected to the atomizing air pump 161, the mixing pump 141 and the atomizing device 151.
The flow rate of the activation air pump 111 is kept constant, and the introduced gas can be air, helium, argon and the like.
The water solution in the activation cavity is medical normal saline, medical purified water and the like.
The plasma generator 121 may be selected from dielectric barrier discharge, corona discharge, sliding arc discharge, and other discharge forms.
Further, in order to ensure higher efficiency of the generated plasma active particles, the plasma generator 121 may be formed by connecting one or more sets of components such as dielectric barrier discharge, corona discharge, sliding arc discharge, and the like in parallel. Wherein the dielectric barrier discharge assembly is not limited to an outer shape.
The high voltage power supply 122 may be any one of a pulse, sinusoidal or dc high voltage power supply.
The water filling port of the activation cavity 131 is sealed under the condition of not adding water, so that the tail gas is prevented from leaking through the water filling port.
The mixing pump is composed of one or more water pumps, and the water discharge rate of the mixing pump 141 can be controlled by the control unit 171, so that the purpose of controlling the concentration of the liquid medicine in the mixed solution is achieved.
Preferably, a display is added to display the pumping rates of the mixing pump from the liquid medicine pool 133 and the activation cavity 131 respectively in real time, so that the concentration of the mixed solution can be accurately calculated.
The atomization device 152 comprises atomization modes such as ultrasonic atomization, compression atomization, micro-grid atomization and the like;
further, the atomization device 152 can control the diameter of the mist particle of the mixed solution to be not more than 5 micrometers by setting oscillation frequency, micro-mesh and the like.
The control unit 171 comprises a single chip microcomputer and a driving amplification circuit, and is used for controlling the high-voltage power supply 122, the activation air pump 111, the mixing pump 141, the atomizing device 152 and the atomizing air pump 161;
further, the control unit 171 may be provided with a mating interface for control and monitoring by an upper computer, and the program written in the control unit may be modified if necessary.
In this embodiment, the plasma generator 121, the activation chamber 131, the balance gas valve 132, and the activation gas pump 111 are connected by gas pipes. The atomizing air pump 161 and the atomizing device 152 are connected by an air pipe. The activation cavity 131, the liquid medicine pool 133, the mixing pump 141 and the atomizing cup 151 are connected through liquid pipelines. The control unit 171 controls the operations of the activation air pump 111, the atomization air pump 161, and the mixing pump 141.
In this example, the aqueous solution is normal saline.
In this embodiment, the flow rate of the activation air pump 111 is 2L/min, the air introduced by the activation air pump 111 and the atomization air pump 161 is air, and the air supply mode is air supply by an air pump.
Further, the gas introduced by the atomizing gas pump 161 may be supplied by a gas cylinder.
In this embodiment, the high voltage power supply 122 is a sinusoidal high voltage power supply module, the output voltage is 6kV, the output frequency is 15kHz, and 220V ac is used as the input of the high voltage power supply module.
In this embodiment, the plasma generator 121 adopts a dielectric barrier discharge structure, the high-voltage copper electrode 211 is a central copper core, an inner glass tube 213 and an outer glass tube 214 are sleeved outside the copper core, the outer glass tube 214 is connected with the ground electrode 212, gas circulates through a gas passage 215 between the inner glass tube and the outer glass tube, and atmospheric pressure cold plasma is also generated in the gas passage 215.
In this embodiment, the power supply for the activation air pump 111, the atomization air pump 161, the mixing pump 141, and the atomization device 152 is provided by the control unit 171, and 220V ac is used as the input of the control unit.
In this embodiment, the balance air valve 132 controls the air pressure in the connecting air path of the activation air pump 111, the plasma generator 121, and the activation chamber 131 to be equal to the external atmospheric pressure.
In this embodiment, when the device is in operation, the water filling port is opened to introduce the physiological saline into the activation chamber 131, the liquid medicine is introduced into the liquid medicine tank 133, and then the water filling port is closed; the control unit 171 controls the activation air pump 111 to work to introduce air into the plasma generator 121; the stable dielectric barrier discharge generated inside the plasma generator 121 generates atmospheric pressure cold plasma, the plasma is blown into the activation cavity 131 under the blowing action of the activation air pump 111, the plasma reacts with the physiological saline, and the active particles with short service life such as 0 and 0H generated by the discharge can be effectively converted into O stably existing in the water solution3And H2O2Storing the water to form plasma active water; the activation cavity 131 and the liquid medicine pool 133 are connected with a mixing pump 141, the plasma active water and the liquid medicine are mixed and introduced into the atomizing cup 151 through the mixing pump 141, and the atomizing device 152 atomizes the mixed solution in the atomizing cup 151 into mixed solution with a specified sizeThe resultant solution mist particles are discharged through a mist outlet under the blowing action of air introduced into the atomizing air pump 161, and are expected to be used for atomizing inhalation therapy.
In this embodiment, the exhaust in the activation chamber 131 is communicated with the activation air pump 111 through the balance air valve 132, at this time, the gas introduced into the plasma generator 121 by the activation air pump 111 is a mixed gas of the plasma exhaust and air, and the plasma active particles in the exhaust are recycled.
In this embodiment, the mixing pump 141 is controlled by the control unit 171, and the chemical liquid, the plasma active water, or the mixed solution of the chemical liquid and the plasma active water can be separately introduced into the atomizing cup 151 by controlling the mixing pump 141, and the concentration of the mixed solution is controlled; the concentration of the mixed solution in the atomizing cup 151 can be controlled by adding a liquid medicine and physiological saline in a specified ratio to the liquid medicine tank 133 and the activation chamber 131 when the operation is started.
In this embodiment, the control module is an STM23F103 series single chip microcomputer, and normal operation of the system is ensured by monitoring the discharge power of the plasma generator 121. When the plasma generator 121 discharges abnormally, the control module is powered off emergently and starts to alarm.
The foregoing describes the general principles of the present application in conjunction with specific embodiments, however, it is noted that the advantages, effects, etc. mentioned in the present application are merely examples and are not limiting, and they should not be considered essential to the various embodiments of the present application. Furthermore, the foregoing disclosure of specific details is for the purpose of illustration and description and is not intended to be limiting, since the foregoing disclosure is not intended to be exhaustive or to limit the disclosure to the precise details disclosed.
The foregoing description has been presented for purposes of illustration and description. Furthermore, the description is not intended to limit embodiments of the application to the form disclosed herein. While a number of example aspects and embodiments have been discussed above, those of skill in the art will recognize certain variations, modifications, alterations, additions and sub-combinations thereof.

Claims (9)

1. A plasma activated water atomizer comprising,
an activation chamber containing an aqueous solution to be activated, the activation chamber comprising a filler and a water outlet;
the plasma generator is powered by a high-voltage power supply, one end of the plasma generator is communicated with the activation air pump, the other end of the plasma generator is communicated with the activation cavity, air is input into the plasma generator through the activation air pump to generate plasma active particles, and the plasma active particles are introduced into the activation cavity under the action of the activation air pump to generate plasma active water with the aqueous solution;
the mixing pump is communicated with a liquid medicine pool containing liquid medicine and the activation cavity through a water outlet, and the mixing pump forms mixed solution by the plasma active water and the liquid medicine according to a preset proportion to pump the mixed solution into the atomizing cup;
an atomizing cup connected to the mixing pump to receive the mixed solution,
an atomizing device for atomizing the mixed solution in the atomizing cup to form mixed solution fog particles with a predetermined size,
an atomizing air pump for pumping out the mixed solution fog particles formed by the atomizing device,
the control unit is connected with the high-voltage power supply, the activation air pump, the atomization air pump and the mixing pump, and sends out a control instruction based on the instruction, controls the high-voltage power supply to provide preset electric energy for the plasma generator to generate plasma active particles, controls the activation air pump to generate plasma active water with a preset volume, controls the mixing pump to generate a mixed solution with a preset concentration and controls the atomization air pump to pump out the mixed solution fog particles at a preset speed.
2. The plasma activated water atomizer of claim 1, wherein preferably, the control unit is further connected to the atomization device, the control unit sending instructions to the atomization device, the atomization device generating the mist of the mixed solution based on the instructions.
3. The plasma-activated water atomizer of claim 1, wherein the activation chamber further comprises an air outlet in communication with the activation air pump via an equalization air valve.
4. The plasma active water atomizer of claim 1, wherein the control unit is a single chip, a digital signal processor, an application specific integrated circuit ASIC, or a field programmable gate array FPGA, the control unit comprising a memory and a timer, the memory comprising one or more of a read only memory ROM, a random access memory RAM, a flash memory, or an electrically erasable programmable read only memory EEPROM.
5. The plasma active water atomizer according to claim 1, wherein the plasma active water atomizer further comprises a voltage sensor for measuring a voltage of a high voltage power supply, a flow rate sensor for measuring a velocity of the mist of the discharged mixed solution, and an alarm unit, the control unit is connected to the voltage sensor, the flow rate sensor, and the alarm unit, and the control unit issues an alarm command to the alarm unit in response to the voltage or the flow rate exceeding a predetermined range.
6. The plasma active water atomizer of claim 1, wherein the plasma generator comprises a central copper core configured as a high voltage electrode, an inner glass tube and an outer glass tube are sleeved outside the central copper core, the outer glass tube is connected to a ground electrode, and gas input through the activation gas pump flows through a gas passage between the inner glass tube and the outer glass tube to generate the atmospheric pressure cold plasma.
7. The plasma active water atomizer according to claim 1, wherein the atomizing means controls a diameter of mist particles of the mixed solution, which is not more than 5 μm, by setting an oscillation frequency or a mesh of a predetermined diameter.
8. The plasma activated water atomizer of claim 1, wherein the atomization means comprises ultrasonic atomization, compression atomization, or micronet atomization.
9. The plasma activated water atomizer of claim 1, wherein the discharge mode of the plasma generator comprises dielectric barrier discharge, jet discharge, corona discharge or sliding arc discharge, and the aqueous solution comprises physiological saline or medical purified water.
CN202010293519.9A 2020-04-14 2020-04-14 Plasma active water atomizer Pending CN111494760A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010293519.9A CN111494760A (en) 2020-04-14 2020-04-14 Plasma active water atomizer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010293519.9A CN111494760A (en) 2020-04-14 2020-04-14 Plasma active water atomizer

Publications (1)

Publication Number Publication Date
CN111494760A true CN111494760A (en) 2020-08-07

Family

ID=71866257

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010293519.9A Pending CN111494760A (en) 2020-04-14 2020-04-14 Plasma active water atomizer

Country Status (1)

Country Link
CN (1) CN111494760A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112972723A (en) * 2021-02-24 2021-06-18 西安交通大学 Discharge plasma disinfection device combining nitrogen oxide mode and ozone mode
CN113104949A (en) * 2021-04-26 2021-07-13 北京农学院 Device and method for preparing activated water by air plasma
CN114105257A (en) * 2020-08-28 2022-03-01 陕西青朗万城环保科技有限公司 Wastewater treatment method based on high-voltage plasma discharge and control system thereof
CN114180659A (en) * 2021-12-24 2022-03-15 西安金山银山科技有限公司 Device and method for treating water body pollution by underwater plasma

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103505757A (en) * 2012-06-30 2014-01-15 成都老肯科技股份有限公司 Plasma air purification-sterilization device
CN105343998A (en) * 2015-12-04 2016-02-24 徐建华 Integrated penetration treatment device used in ear-nose-throat department
CN106975329A (en) * 2017-04-13 2017-07-25 上海大学 Vacuum plasma stacked tubular air purifier
CN107569749A (en) * 2017-08-23 2018-01-12 苏州浩哥文化传播有限公司 The Multi-functional atomization therapeutic equipment and its method of work of a kind of self-cleaning
CN108498910A (en) * 2018-05-02 2018-09-07 马云玲 A kind of intelligence Medical children atomizer
CN208389130U (en) * 2017-07-10 2019-01-18 西安交通大学医学院第一附属医院 A kind of vaporizer
CN110092446A (en) * 2018-01-29 2019-08-06 西安交通大学 The system and method for plasma-activated water of the preparation for sterilizing in cavity
US10576239B2 (en) * 2017-02-27 2020-03-03 Third Pole, Inc. System and methods for ambulatory generation of nitric oxide
CN110913553A (en) * 2019-12-12 2020-03-24 大连理工大学 High-efficient plasma activated water produces equipment

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103505757A (en) * 2012-06-30 2014-01-15 成都老肯科技股份有限公司 Plasma air purification-sterilization device
CN105343998A (en) * 2015-12-04 2016-02-24 徐建华 Integrated penetration treatment device used in ear-nose-throat department
US10576239B2 (en) * 2017-02-27 2020-03-03 Third Pole, Inc. System and methods for ambulatory generation of nitric oxide
CN106975329A (en) * 2017-04-13 2017-07-25 上海大学 Vacuum plasma stacked tubular air purifier
CN208389130U (en) * 2017-07-10 2019-01-18 西安交通大学医学院第一附属医院 A kind of vaporizer
CN107569749A (en) * 2017-08-23 2018-01-12 苏州浩哥文化传播有限公司 The Multi-functional atomization therapeutic equipment and its method of work of a kind of self-cleaning
CN110092446A (en) * 2018-01-29 2019-08-06 西安交通大学 The system and method for plasma-activated water of the preparation for sterilizing in cavity
CN108498910A (en) * 2018-05-02 2018-09-07 马云玲 A kind of intelligence Medical children atomizer
CN110913553A (en) * 2019-12-12 2020-03-24 大连理工大学 High-efficient plasma activated water produces equipment

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114105257A (en) * 2020-08-28 2022-03-01 陕西青朗万城环保科技有限公司 Wastewater treatment method based on high-voltage plasma discharge and control system thereof
CN112972723A (en) * 2021-02-24 2021-06-18 西安交通大学 Discharge plasma disinfection device combining nitrogen oxide mode and ozone mode
CN112972723B (en) * 2021-02-24 2021-11-30 西安交通大学 Discharge plasma disinfection device combining nitrogen oxide mode and ozone mode
CN113104949A (en) * 2021-04-26 2021-07-13 北京农学院 Device and method for preparing activated water by air plasma
CN114180659A (en) * 2021-12-24 2022-03-15 西安金山银山科技有限公司 Device and method for treating water body pollution by underwater plasma
CN114180659B (en) * 2021-12-24 2023-10-13 西安金山银山科技有限公司 Device and method for treating water pollution by underwater plasma

Similar Documents

Publication Publication Date Title
CN111494760A (en) Plasma active water atomizer
CN106512157B (en) A kind of full respiratory drugs gatherer of automatic high-frequency ultrasonic atomizatio
CN111494774A (en) Plasma active gas humidifier
CN112978847A (en) Nitrogen-oxygen ratio-based plasma activated water disinfection device and method
CN210873815U (en) Tuberculosis prevention and cure degassing unit
CN111298251A (en) Device with COVID-19 virus prevention and treatment functions
CN106730183A (en) A kind of respiratory system therapeutic device
US20210299292A1 (en) Method to Kill Respiratory Viruses and Microbes by Water Mist Charge
CN104208778A (en) Nebulization drug delivery system for respiratory circuit
CN205031675U (en) Compression nebulizer of area ultraviolet ray sterilization function
JP4675566B2 (en) Inhaler
CN207855993U (en) A kind of lung ventilator exhalation circuit chlorination equipment
CN110074308A (en) Electrostatic aerosol method for disinfection and sterilization, system and equipment
CN103961771A (en) Medical compression type atomizer
CN212204868U (en) Sterilizing and humidifying device
CN208905884U (en) A kind of volatility medical fluid nasal cavity inhalation instrument
CN110314620B (en) High-efficient gas-liquid mixture device that sprays
CN204106767U (en) For the atomized medicine introducing system of breathing circuit
CN113332544A (en) A atomizer for paediatrics respiratory track treatment
CN212631752U (en) Miniaturized atomizer
CN205515839U (en) Atomizer and atomizer main part
CN201267665Y (en) Auxiliary atomizer of breathing machine
CN215024281U (en) Breathe clinical atomizing oxygenerator of internal medicine
CN107596514A (en) A kind of atomization inspiration treatment device for children's clinical treatment
CN212631370U (en) Respiratory system for atomization drug delivery

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20200807

RJ01 Rejection of invention patent application after publication