JP4659219B2 - Fusedのヒトサプレッサー - Google Patents

Fusedのヒトサプレッサー Download PDF

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Publication number
JP4659219B2
JP4659219B2 JP2000602778A JP2000602778A JP4659219B2 JP 4659219 B2 JP4659219 B2 JP 4659219B2 JP 2000602778 A JP2000602778 A JP 2000602778A JP 2000602778 A JP2000602778 A JP 2000602778A JP 4659219 B2 JP4659219 B2 JP 4659219B2
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JP
Japan
Prior art keywords
hsu
polypeptide
sequence
cell
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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JP2000602778A
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English (en)
Japanese (ja)
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JP2002537812A (ja
JP2002537812A5 (https=
Inventor
ソーバージュ,フレデリック ジェー. デ
ガーニー,オースティン,エル.
ムロン,マクシミリアン
ローゼンタール,アーノン
ストーン,ドンナ,エム.
ウッド,ウィリアム,アイ.
Original Assignee
ジェネンテック, インコーポレイテッド
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Publication of JP2002537812A publication Critical patent/JP2002537812A/ja
Publication of JP2002537812A5 publication Critical patent/JP2002537812A5/ja
Application granted granted Critical
Publication of JP4659219B2 publication Critical patent/JP4659219B2/ja
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4703Inhibitors; Suppressors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Glass Compositions (AREA)
JP2000602778A 1999-03-05 2000-03-02 Fusedのヒトサプレッサー Expired - Lifetime JP4659219B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12309099P 1999-03-05 1999-03-05
US60/123,090 1999-03-05
US13573699P 1999-05-25 1999-05-25
US60/135,736 1999-05-25
PCT/US2000/005746 WO2000052166A1 (en) 1999-03-05 2000-03-02 Human suppressor of fused

Publications (3)

Publication Number Publication Date
JP2002537812A JP2002537812A (ja) 2002-11-12
JP2002537812A5 JP2002537812A5 (https=) 2007-04-19
JP4659219B2 true JP4659219B2 (ja) 2011-03-30

Family

ID=26821226

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000602778A Expired - Lifetime JP4659219B2 (ja) 1999-03-05 2000-03-02 Fusedのヒトサプレッサー

Country Status (9)

Country Link
EP (1) EP1159421B8 (https=)
JP (1) JP4659219B2 (https=)
KR (1) KR100721484B1 (https=)
AT (1) ATE447614T1 (https=)
AU (1) AU779258B2 (https=)
CA (1) CA2362963C (https=)
DE (1) DE60043258D1 (https=)
NZ (1) NZ513762A (https=)
WO (1) WO2000052166A1 (https=)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6448020B1 (en) * 1997-12-19 2002-09-10 Rune Toftgard Molecules associated with the human suppressor of fused gene

Also Published As

Publication number Publication date
EP1159421B1 (en) 2009-11-04
DE60043258D1 (de) 2009-12-17
ATE447614T1 (de) 2009-11-15
NZ513762A (en) 2001-09-28
CA2362963C (en) 2014-05-06
JP2002537812A (ja) 2002-11-12
CA2362963A1 (en) 2000-09-08
WO2000052166A1 (en) 2000-09-08
AU779258B2 (en) 2005-01-13
KR100721484B1 (ko) 2007-05-23
AU3867000A (en) 2000-09-21
EP1159421B8 (en) 2010-02-17
EP1159421A1 (en) 2001-12-05
KR20010113036A (ko) 2001-12-24

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