JP4602764B2 - うっ血性心不全を予測するシステム - Google Patents
うっ血性心不全を予測するシステム Download PDFInfo
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- JP4602764B2 JP4602764B2 JP2004526055A JP2004526055A JP4602764B2 JP 4602764 B2 JP4602764 B2 JP 4602764B2 JP 2004526055 A JP2004526055 A JP 2004526055A JP 2004526055 A JP2004526055 A JP 2004526055A JP 4602764 B2 JP4602764 B2 JP 4602764B2
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- implantable
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- Expired - Fee Related
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/3627—Heart stimulators for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4842—Monitoring progression or stage of a disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Surgery (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/213,268 US7127290B2 (en) | 1999-10-01 | 2002-08-06 | Cardiac rhythm management systems and methods predicting congestive heart failure status |
| PCT/US2003/024597 WO2004012815A1 (en) | 2002-08-06 | 2003-08-06 | Systems predicting congestive heart failure |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005534406A JP2005534406A (ja) | 2005-11-17 |
| JP2005534406A5 JP2005534406A5 (https=) | 2009-12-24 |
| JP4602764B2 true JP4602764B2 (ja) | 2010-12-22 |
Family
ID=31494431
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004526055A Expired - Fee Related JP4602764B2 (ja) | 2002-08-06 | 2003-08-06 | うっ血性心不全を予測するシステム |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7127290B2 (https=) |
| EP (1) | EP1539296A1 (https=) |
| JP (1) | JP4602764B2 (https=) |
| AU (1) | AU2003261399A1 (https=) |
| WO (1) | WO2004012815A1 (https=) |
Families Citing this family (230)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USD386557S (en) * | 1996-06-10 | 1997-11-18 | David Thompson | Fishing rod holder |
| US20030036746A1 (en) | 2001-08-16 | 2003-02-20 | Avi Penner | Devices for intrabody delivery of molecules and systems and methods utilizing same |
| US7945451B2 (en) * | 1999-04-16 | 2011-05-17 | Cardiocom, Llc | Remote monitoring system for ambulatory patients |
| US6290646B1 (en) * | 1999-04-16 | 2001-09-18 | Cardiocom | Apparatus and method for monitoring and communicating wellness parameters of ambulatory patients |
| US7577475B2 (en) * | 1999-04-16 | 2009-08-18 | Cardiocom | System, method, and apparatus for combining information from an implanted device with information from a patient monitoring apparatus |
| US8438038B2 (en) | 1999-04-16 | 2013-05-07 | Cardiocom, Llc | Weight loss or weight management system |
| US8419650B2 (en) | 1999-04-16 | 2013-04-16 | Cariocom, LLC | Downloadable datasets for a patient monitoring system |
| US6270457B1 (en) | 1999-06-03 | 2001-08-07 | Cardiac Intelligence Corp. | System and method for automated collection and analysis of regularly retrieved patient information for remote patient care |
| US7134996B2 (en) * | 1999-06-03 | 2006-11-14 | Cardiac Intelligence Corporation | System and method for collection and analysis of patient information for automated remote patient care |
| CA2314513A1 (en) * | 1999-07-26 | 2001-01-26 | Gust H. Bardy | System and method for providing normalized voice feedback from an individual patient in an automated collection and analysis patient care system |
| US6272377B1 (en) * | 1999-10-01 | 2001-08-07 | Cardiac Pacemakers, Inc. | Cardiac rhythm management system with arrhythmia prediction and prevention |
| US6328699B1 (en) * | 2000-01-11 | 2001-12-11 | Cedars-Sinai Medical Center | Permanently implantable system and method for detecting, diagnosing and treating congestive heart failure |
| US8298150B2 (en) * | 2000-01-11 | 2012-10-30 | Cedars-Sinai Medical Center | Hemodynamic waveform-based diagnosis and treatment |
| US6970742B2 (en) * | 2000-01-11 | 2005-11-29 | Savacor, Inc. | Method for detecting, diagnosing, and treating cardiovascular disease |
| US8043224B2 (en) * | 2000-07-12 | 2011-10-25 | Dimicine Research It, Llc | Telemedicine system |
| US7024248B2 (en) | 2000-10-16 | 2006-04-04 | Remon Medical Technologies Ltd | Systems and methods for communicating with implantable devices |
| US7191000B2 (en) * | 2001-07-31 | 2007-03-13 | Cardiac Pacemakers, Inc. | Cardiac rhythm management system for edema |
| US6973349B2 (en) * | 2001-12-05 | 2005-12-06 | Cardiac Pacemakers, Inc. | Method and apparatus for minimizing post-infarct ventricular remodeling |
| US8391989B2 (en) | 2002-12-18 | 2013-03-05 | Cardiac Pacemakers, Inc. | Advanced patient management for defining, identifying and using predetermined health-related events |
| US7983759B2 (en) | 2002-12-18 | 2011-07-19 | Cardiac Pacemakers, Inc. | Advanced patient management for reporting multiple health-related parameters |
| US7113825B2 (en) * | 2002-05-03 | 2006-09-26 | Cardiac Pacemakers, Inc. | Method and apparatus for detecting acoustic oscillations in cardiac rhythm |
| US7039462B2 (en) * | 2002-06-14 | 2006-05-02 | Cardiac Pacemakers, Inc. | Method and apparatus for detecting oscillations in cardiac rhythm |
| US6965797B2 (en) * | 2002-09-13 | 2005-11-15 | Cardiac Pacemakers, Inc. | Method and apparatus for assessing and treating myocardial wall stress |
| US7226422B2 (en) * | 2002-10-09 | 2007-06-05 | Cardiac Pacemakers, Inc. | Detection of congestion from monitoring patient response to a recumbent position |
| US7313434B2 (en) * | 2002-11-25 | 2007-12-25 | Regents Of The University Of Minnesota | Impedance monitoring for detecting pulmonary edema and thoracic congestion |
| AU2003297583B2 (en) | 2002-11-26 | 2010-01-14 | Biocon, Ltd | Modified naturetic compounds, conjugates, and uses thereof |
| US7189204B2 (en) | 2002-12-04 | 2007-03-13 | Cardiac Pacemakers, Inc. | Sleep detection using an adjustable threshold |
| US7252640B2 (en) * | 2002-12-04 | 2007-08-07 | Cardiac Pacemakers, Inc. | Detection of disordered breathing |
| US7101339B2 (en) * | 2002-12-13 | 2006-09-05 | Cardiac Pacemakers, Inc. | Respiration signal measurement apparatus, systems, and methods |
| US6949075B2 (en) * | 2002-12-27 | 2005-09-27 | Cardiac Pacemakers, Inc. | Apparatus and method for detecting lung sounds using an implanted device |
| US20050080348A1 (en) * | 2003-09-18 | 2005-04-14 | Stahmann Jeffrey E. | Medical event logbook system and method |
| US8951205B2 (en) | 2002-12-30 | 2015-02-10 | Cardiac Pacemakers, Inc. | Method and apparatus for detecting atrial filling pressure |
| US7972275B2 (en) * | 2002-12-30 | 2011-07-05 | Cardiac Pacemakers, Inc. | Method and apparatus for monitoring of diastolic hemodynamics |
| US7499750B2 (en) * | 2003-04-11 | 2009-03-03 | Cardiac Pacemakers, Inc. | Noise canceling cardiac electrodes |
| US6999816B2 (en) * | 2003-04-23 | 2006-02-14 | Medtronic, Inc. | Detecting heart tones to identify heart deterioration |
| US7477932B2 (en) | 2003-05-28 | 2009-01-13 | Cardiac Pacemakers, Inc. | Cardiac waveform template creation, maintenance and use |
| US7200440B2 (en) | 2003-07-02 | 2007-04-03 | Cardiac Pacemakers, Inc. | Cardiac cycle synchronized sampling of impedance signal |
| US7186220B2 (en) | 2003-07-02 | 2007-03-06 | Cardiac Pacemakers, Inc. | Implantable devices and methods using frequency-domain analysis of thoracic signal |
| US7662101B2 (en) * | 2003-09-18 | 2010-02-16 | Cardiac Pacemakers, Inc. | Therapy control based on cardiopulmonary status |
| US7720541B2 (en) * | 2003-08-18 | 2010-05-18 | Cardiac Pacemakers, Inc. | Adaptive therapy for disordered breathing |
| US20050142070A1 (en) * | 2003-09-18 | 2005-06-30 | Hartley Jesse W. | Methods and systems for assessing pulmonary disease with drug therapy control |
| US7572225B2 (en) * | 2003-09-18 | 2009-08-11 | Cardiac Pacemakers, Inc. | Sleep logbook |
| US7468040B2 (en) | 2003-09-18 | 2008-12-23 | Cardiac Pacemakers, Inc. | Methods and systems for implantably monitoring external breathing therapy |
| US7591265B2 (en) * | 2003-09-18 | 2009-09-22 | Cardiac Pacemakers, Inc. | Coordinated use of respiratory and cardiac therapies for sleep disordered breathing |
| US8192376B2 (en) | 2003-08-18 | 2012-06-05 | Cardiac Pacemakers, Inc. | Sleep state classification |
| US7610094B2 (en) * | 2003-09-18 | 2009-10-27 | Cardiac Pacemakers, Inc. | Synergistic use of medical devices for detecting medical disorders |
| US7469697B2 (en) * | 2003-09-18 | 2008-12-30 | Cardiac Pacemakers, Inc. | Feedback system and method for sleep disordered breathing therapy |
| US7787946B2 (en) | 2003-08-18 | 2010-08-31 | Cardiac Pacemakers, Inc. | Patient monitoring, diagnosis, and/or therapy systems and methods |
| US7510531B2 (en) | 2003-09-18 | 2009-03-31 | Cardiac Pacemakers, Inc. | System and method for discrimination of central and obstructive disordered breathing events |
| US8606356B2 (en) | 2003-09-18 | 2013-12-10 | Cardiac Pacemakers, Inc. | Autonomic arousal detection system and method |
| US7680537B2 (en) * | 2003-08-18 | 2010-03-16 | Cardiac Pacemakers, Inc. | Therapy triggered by prediction of disordered breathing |
| US7575553B2 (en) * | 2003-09-18 | 2009-08-18 | Cardiac Pacemakers, Inc. | Methods and systems for assessing pulmonary disease |
| US7757690B2 (en) | 2003-09-18 | 2010-07-20 | Cardiac Pacemakers, Inc. | System and method for moderating a therapy delivered during sleep using physiologic data acquired during non-sleep |
| US7396333B2 (en) | 2003-08-18 | 2008-07-08 | Cardiac Pacemakers, Inc. | Prediction of disordered breathing |
| US8002553B2 (en) | 2003-08-18 | 2011-08-23 | Cardiac Pacemakers, Inc. | Sleep quality data collection and evaluation |
| US7616988B2 (en) * | 2003-09-18 | 2009-11-10 | Cardiac Pacemakers, Inc. | System and method for detecting an involuntary muscle movement disorder |
| US7678061B2 (en) * | 2003-09-18 | 2010-03-16 | Cardiac Pacemakers, Inc. | System and method for characterizing patient respiration |
| US7336996B2 (en) * | 2003-09-18 | 2008-02-26 | Cardiac Pacemakers, Inc. | Rate regularization of cardiac pacing for disordered breathing therapy |
| US7887493B2 (en) | 2003-09-18 | 2011-02-15 | Cardiac Pacemakers, Inc. | Implantable device employing movement sensing for detecting sleep-related disorders |
| US7967756B2 (en) * | 2003-09-18 | 2011-06-28 | Cardiac Pacemakers, Inc. | Respiratory therapy control based on cardiac cycle |
| US7668591B2 (en) * | 2003-09-18 | 2010-02-23 | Cardiac Pacemakers, Inc. | Automatic activation of medical processes |
| US8251061B2 (en) * | 2003-09-18 | 2012-08-28 | Cardiac Pacemakers, Inc. | Methods and systems for control of gas therapy |
| US7632234B2 (en) * | 2003-08-29 | 2009-12-15 | Medtronic, Inc. | Implantable biosensor devices for monitoring cardiac marker molecules |
| AU2003295346A1 (en) | 2003-10-14 | 2004-06-06 | Cardiac Pacemakers, Inc. | Detection of congestion from monitoring patient response to a recumbent position |
| US7248923B2 (en) | 2003-11-06 | 2007-07-24 | Cardiac Pacemakers, Inc. | Dual-use sensor for rate responsive pacing and heart sound monitoring |
| US20060247693A1 (en) | 2005-04-28 | 2006-11-02 | Yanting Dong | Non-captured intrinsic discrimination in cardiac pacing response classification |
| US7319900B2 (en) | 2003-12-11 | 2008-01-15 | Cardiac Pacemakers, Inc. | Cardiac response classification using multiple classification windows |
| US7774064B2 (en) | 2003-12-12 | 2010-08-10 | Cardiac Pacemakers, Inc. | Cardiac response classification using retriggerable classification windows |
| US8521284B2 (en) | 2003-12-12 | 2013-08-27 | Cardiac Pacemakers, Inc. | Cardiac response classification using multisite sensing and pacing |
| EP1711222A4 (en) * | 2003-12-19 | 2011-02-09 | Savacor Inc | DIGITAL ELECTRODE FOR HEART RTHYTHMUS MANAGEMENT |
| US8396560B2 (en) | 2004-11-18 | 2013-03-12 | Cardiac Pacemakers, Inc. | System and method for closed-loop neural stimulation |
| US7769450B2 (en) | 2004-11-18 | 2010-08-03 | Cardiac Pacemakers, Inc. | Cardiac rhythm management device with neural sensor |
| US7115096B2 (en) * | 2003-12-24 | 2006-10-03 | Cardiac Pacemakers, Inc. | Third heart sound activity index for heart failure monitoring |
| US7254440B1 (en) | 2004-01-26 | 2007-08-07 | Pacesetter, Inc. | Implantable ischemia and myocardial infarction monitor and method |
| US7272443B2 (en) | 2004-03-26 | 2007-09-18 | Pacesetter, Inc. | System and method for predicting a heart condition based on impedance values using an implantable medical device |
| US7505814B2 (en) * | 2004-03-26 | 2009-03-17 | Pacesetter, Inc. | System and method for evaluating heart failure based on ventricular end-diastolic volume using an implantable medical device |
| US7171271B2 (en) * | 2004-05-11 | 2007-01-30 | Pacesetter, Inc. | System and method for evaluating heart failure using an implantable medical device based on heart rate during patient activity |
| US7747323B2 (en) | 2004-06-08 | 2010-06-29 | Cardiac Pacemakers, Inc. | Adaptive baroreflex stimulation therapy for disordered breathing |
| US7209786B2 (en) * | 2004-06-10 | 2007-04-24 | Cardiac Pacemakers, Inc. | Method and apparatus for optimization of cardiac resynchronization therapy using heart sounds |
| US7706866B2 (en) | 2004-06-24 | 2010-04-27 | Cardiac Pacemakers, Inc. | Automatic orientation determination for ECG measurements using multiple electrodes |
| US7433853B2 (en) | 2004-07-12 | 2008-10-07 | Cardiac Pacemakers, Inc. | Expert system for patient medical information analysis |
| US7480528B2 (en) * | 2004-07-23 | 2009-01-20 | Cardiac Pacemakers, Inc. | Method and apparatus for monitoring heart failure patients with cardiopulmonary comorbidities |
| US7559901B2 (en) * | 2004-07-28 | 2009-07-14 | Cardiac Pacemakers, Inc. | Determining a patient's posture from mechanical vibrations of the heart |
| US7277756B2 (en) * | 2004-08-16 | 2007-10-02 | Cardiac Pacemakers, Inc. | Risk of death indicator |
| US7387610B2 (en) | 2004-08-19 | 2008-06-17 | Cardiac Pacemakers, Inc. | Thoracic impedance detection with blood resistivity compensation |
| US8271093B2 (en) | 2004-09-17 | 2012-09-18 | Cardiac Pacemakers, Inc. | Systems and methods for deriving relative physiologic measurements using a backend computing system |
| US7805185B2 (en) | 2005-05-09 | 2010-09-28 | Cardiac Pacemakers, In. | Posture monitoring using cardiac activation sequences |
| US7457664B2 (en) * | 2005-05-09 | 2008-11-25 | Cardiac Pacemakers, Inc. | Closed loop cardiac resynchronization therapy using cardiac activation sequence information |
| US7917196B2 (en) | 2005-05-09 | 2011-03-29 | Cardiac Pacemakers, Inc. | Arrhythmia discrimination using electrocardiograms sensed from multiple implanted electrodes |
| US7509170B2 (en) | 2005-05-09 | 2009-03-24 | Cardiac Pacemakers, Inc. | Automatic capture verification using electrocardiograms sensed from multiple implanted electrodes |
| US7890159B2 (en) | 2004-09-30 | 2011-02-15 | Cardiac Pacemakers, Inc. | Cardiac activation sequence monitoring and tracking |
| ATE484232T1 (de) | 2004-11-24 | 2010-10-15 | Remon Medical Technologies Ltd | Implantierbares medizinprodukt mit integriertem akustischem wandler |
| US7813808B1 (en) | 2004-11-24 | 2010-10-12 | Remon Medical Technologies Ltd | Implanted sensor system with optimized operational and sensing parameters |
| US7522962B1 (en) | 2004-12-03 | 2009-04-21 | Remon Medical Technologies, Ltd | Implantable medical device with integrated acoustic transducer |
| US7996072B2 (en) | 2004-12-21 | 2011-08-09 | Cardiac Pacemakers, Inc. | Positionally adaptable implantable cardiac device |
| JP2006185060A (ja) * | 2004-12-27 | 2006-07-13 | Fujitsu Ltd | パスワード入力方法 |
| US20060149324A1 (en) * | 2004-12-30 | 2006-07-06 | Brian Mann | Cardiac rhythm management with interchangeable components |
| US20060149330A1 (en) * | 2004-12-30 | 2006-07-06 | Brian Mann | Digitally controlled cardiac rhythm management |
| US7295874B2 (en) | 2005-01-06 | 2007-11-13 | Cardiac Pacemakers, Inc. | Intermittent stress augmentation pacing for cardioprotective effect |
| WO2006076471A2 (en) * | 2005-01-12 | 2006-07-20 | Nobex Corporation | Bnp conjugates and methods of use |
| US7662104B2 (en) * | 2005-01-18 | 2010-02-16 | Cardiac Pacemakers, Inc. | Method for correction of posture dependence on heart sounds |
| US7386345B2 (en) * | 2005-01-27 | 2008-06-10 | Cardiac Pacemakers, Inc. | Apparatus and method for temporary treatment of acute heart failure decompensation |
| US8594790B2 (en) * | 2005-01-27 | 2013-11-26 | Medtronic, Inc. | System and method for monitoring a ventricular pressure index to predict worsening heart failure |
| US7680534B2 (en) | 2005-02-28 | 2010-03-16 | Cardiac Pacemakers, Inc. | Implantable cardiac device with dyspnea measurement |
| US9555252B2 (en) * | 2005-04-25 | 2017-01-31 | Cardiac Pacemakers, Inc. | Systems for providing neural markers for sensed autonomic nervous system activity |
| US7640057B2 (en) * | 2005-04-25 | 2009-12-29 | Cardiac Pacemakers, Inc. | Methods of providing neural markers for sensed autonomic nervous system activity |
| US7392086B2 (en) | 2005-04-26 | 2008-06-24 | Cardiac Pacemakers, Inc. | Implantable cardiac device and method for reduced phrenic nerve stimulation |
| US7603170B2 (en) * | 2005-04-26 | 2009-10-13 | Cardiac Pacemakers, Inc. | Calibration of impedance monitoring of respiratory volumes using thoracic D.C. impedance |
| US20060243280A1 (en) | 2005-04-27 | 2006-11-02 | Caro Richard G | Method of determining lung condition indicators |
| US7769451B2 (en) * | 2005-04-28 | 2010-08-03 | Medtronic, Inc. | Method and apparatus for optimizing cardiac resynchronization therapy |
| WO2006117780A2 (en) | 2005-04-29 | 2006-11-09 | Oren Gavriely | Cough detector |
| US7630755B2 (en) | 2005-05-04 | 2009-12-08 | Cardiac Pacemakers Inc. | Syncope logbook and method of using same |
| US9089275B2 (en) * | 2005-05-11 | 2015-07-28 | Cardiac Pacemakers, Inc. | Sensitivity and specificity of pulmonary edema detection when using transthoracic impedance |
| US7907997B2 (en) * | 2005-05-11 | 2011-03-15 | Cardiac Pacemakers, Inc. | Enhancements to the detection of pulmonary edema when using transthoracic impedance |
| US7917210B2 (en) * | 2005-05-13 | 2011-03-29 | Cardiac Pacemakers, Inc. | Method and apparatus for cardiac protection pacing |
| US7894896B2 (en) * | 2005-05-13 | 2011-02-22 | Cardiac Pacemakers, Inc. | Method and apparatus for initiating and delivering cardiac protection pacing |
| US7340296B2 (en) | 2005-05-18 | 2008-03-04 | Cardiac Pacemakers, Inc. | Detection of pleural effusion using transthoracic impedance |
| US7526338B1 (en) * | 2005-05-23 | 2009-04-28 | Pacesetter, Inc. | Implantable cardiac device for monitoring diastolic heart failure and method of operation and use thereof |
| US8900154B2 (en) * | 2005-05-24 | 2014-12-02 | Cardiac Pacemakers, Inc. | Prediction of thoracic fluid accumulation |
| US8972002B2 (en) | 2005-06-01 | 2015-03-03 | Cardiac Pacemakers, Inc. | Remote closed-loop titration of decongestive therapy for the treatment of advanced heart failure |
| US7670298B2 (en) | 2005-06-01 | 2010-03-02 | Cardiac Pacemakers, Inc. | Sensing rate of change of pressure in the left ventricle with an implanted device |
| US7922669B2 (en) | 2005-06-08 | 2011-04-12 | Cardiac Pacemakers, Inc. | Ischemia detection using a heart sound sensor |
| US7460909B1 (en) | 2005-08-16 | 2008-12-02 | Pacesetter, Inc. | Implantable device for monitoring hemodynamic profiles |
| US7634309B2 (en) * | 2005-08-19 | 2009-12-15 | Cardiac Pacemakers, Inc. | Tracking progression of congestive heart failure via a force-frequency relationship |
| US7570998B2 (en) * | 2005-08-26 | 2009-08-04 | Cardiac Pacemakers, Inc. | Acoustic communication transducer in implantable medical device header |
| US7615012B2 (en) | 2005-08-26 | 2009-11-10 | Cardiac Pacemakers, Inc. | Broadband acoustic sensor for an implantable medical device |
| US20070055115A1 (en) * | 2005-09-08 | 2007-03-08 | Jonathan Kwok | Characterization of sleep disorders using composite patient data |
| US7742815B2 (en) | 2005-09-09 | 2010-06-22 | Cardiac Pacemakers, Inc. | Using implanted sensors for feedback control of implanted medical devices |
| US7775983B2 (en) * | 2005-09-16 | 2010-08-17 | Cardiac Pacemakers, Inc. | Rapid shallow breathing detection for use in congestive heart failure status determination |
| US7731663B2 (en) * | 2005-09-16 | 2010-06-08 | Cardiac Pacemakers, Inc. | System and method for generating a trend parameter based on respiration rate distribution |
| US20070118180A1 (en) | 2005-11-18 | 2007-05-24 | Quan Ni | Cardiac resynchronization therapy for improved hemodynamics based on disordered breathing detection |
| US8108034B2 (en) | 2005-11-28 | 2012-01-31 | Cardiac Pacemakers, Inc. | Systems and methods for valvular regurgitation detection |
| US7766840B2 (en) * | 2005-12-01 | 2010-08-03 | Cardiac Pacemakers, Inc. | Method and system for heart failure status evaluation based on a disordered breathing index |
| US20070129641A1 (en) * | 2005-12-01 | 2007-06-07 | Sweeney Robert J | Posture estimation at transitions between states |
| US7580746B2 (en) * | 2005-12-07 | 2009-08-25 | Cardiac Pacemakers, Inc. | Implantable medical device for generating cardiac pressure-volume loop and optimizing therapy |
| US7662105B2 (en) | 2005-12-14 | 2010-02-16 | Cardiac Pacemakers, Inc. | Systems and methods for determining respiration metrics |
| US7713213B2 (en) * | 2006-03-13 | 2010-05-11 | Cardiac Pacemakers, Inc. | Physiological event detection systems and methods |
| US7819816B2 (en) * | 2006-03-29 | 2010-10-26 | Cardiac Pacemakers, Inc. | Periodic disordered breathing detection |
| US7780606B2 (en) * | 2006-03-29 | 2010-08-24 | Cardiac Pacemakers, Inc. | Hemodynamic stability assessment based on heart sounds |
| US7794404B1 (en) | 2006-03-31 | 2010-09-14 | Pacesetter, Inc | System and method for estimating cardiac pressure using parameters derived from impedance signals detected by an implantable medical device |
| US20070255345A1 (en) * | 2006-04-26 | 2007-11-01 | Krause Paul G | Method and System for Triggering an Implantable Medical Device for Risk Stratification Measurements |
| US8005543B2 (en) | 2006-05-08 | 2011-08-23 | Cardiac Pacemakers, Inc. | Heart failure management system |
| US8000780B2 (en) * | 2006-06-27 | 2011-08-16 | Cardiac Pacemakers, Inc. | Detection of myocardial ischemia from the time sequence of implanted sensor measurements |
| US8527048B2 (en) | 2006-06-29 | 2013-09-03 | Cardiac Pacemakers, Inc. | Local and non-local sensing for cardiac pacing |
| US7955268B2 (en) | 2006-07-21 | 2011-06-07 | Cardiac Pacemakers, Inc. | Multiple sensor deployment |
| EP2043740A2 (en) | 2006-07-21 | 2009-04-08 | Cardiac Pacemakers, Inc. | Ultrasonic transducer for a metallic cavity implanted medical device |
| US7912548B2 (en) * | 2006-07-21 | 2011-03-22 | Cardiac Pacemakers, Inc. | Resonant structures for implantable devices |
| US7580741B2 (en) | 2006-08-18 | 2009-08-25 | Cardiac Pacemakers, Inc. | Method and device for determination of arrhythmia rate zone thresholds using a probability function |
| US8343049B2 (en) | 2006-08-24 | 2013-01-01 | Cardiac Pacemakers, Inc. | Physiological response to posture change |
| US8103341B2 (en) * | 2006-08-25 | 2012-01-24 | Cardiac Pacemakers, Inc. | System for abating neural stimulation side effects |
| US8712507B2 (en) | 2006-09-14 | 2014-04-29 | Cardiac Pacemakers, Inc. | Systems and methods for arranging and labeling cardiac episodes |
| US8209013B2 (en) | 2006-09-14 | 2012-06-26 | Cardiac Pacemakers, Inc. | Therapeutic electrical stimulation that avoids undesirable activation |
| US20080091114A1 (en) * | 2006-10-11 | 2008-04-17 | Pacesetter, Inc. | Techniques for Correlating Thoracic Impedance with Physiological Status |
| US7764996B2 (en) | 2006-10-31 | 2010-07-27 | Cardiac Pacemakers, Inc. | Monitoring of chronobiological rhythms for disease and drug management using one or more implantable device |
| US20080119749A1 (en) | 2006-11-20 | 2008-05-22 | Cardiac Pacemakers, Inc. | Respiration-synchronized heart sound trending |
| US8096954B2 (en) | 2006-11-29 | 2012-01-17 | Cardiac Pacemakers, Inc. | Adaptive sampling of heart sounds |
| US7941208B2 (en) | 2006-11-29 | 2011-05-10 | Cardiac Pacemakers, Inc. | Therapy delivery for identified tachyarrhythmia episode types |
| US7629889B2 (en) | 2006-12-27 | 2009-12-08 | Cardiac Pacemakers, Inc. | Within-patient algorithm to predict heart failure decompensation |
| US9968266B2 (en) | 2006-12-27 | 2018-05-15 | Cardiac Pacemakers, Inc. | Risk stratification based heart failure detection algorithm |
| US8768718B2 (en) * | 2006-12-27 | 2014-07-01 | Cardiac Pacemakers, Inc. | Between-patient comparisons for risk stratification of future heart failure decompensation |
| US9022930B2 (en) * | 2006-12-27 | 2015-05-05 | Cardiac Pacemakers, Inc. | Inter-relation between within-patient decompensation detection algorithm and between-patient stratifier to manage HF patients in a more efficient manner |
| US7736319B2 (en) * | 2007-01-19 | 2010-06-15 | Cardiac Pacemakers, Inc. | Ischemia detection using heart sound timing |
| US8014863B2 (en) * | 2007-01-19 | 2011-09-06 | Cardiac Pacemakers, Inc. | Heart attack or ischemia detector |
| US8065001B1 (en) * | 2007-03-01 | 2011-11-22 | Pacesetter, Inc. | Use of implantable body position and body movement sensors |
| US8615296B2 (en) * | 2007-03-06 | 2013-12-24 | Cardiac Pacemakers, Inc. | Method and apparatus for closed-loop intermittent cardiac stress augmentation pacing |
| US8052611B2 (en) | 2007-03-14 | 2011-11-08 | Cardiac Pacemakers, Inc. | Method and apparatus for management of heart failure hospitalization |
| US8406877B2 (en) * | 2007-03-19 | 2013-03-26 | Cardiac Pacemakers, Inc. | Selective nerve stimulation with optionally closed-loop capabilities |
| US8208999B2 (en) | 2007-04-04 | 2012-06-26 | Pacesetter, Inc. | System and method for estimating electrical conduction delays from immittance values measured using an implantable medical device |
| US8504152B2 (en) | 2007-04-04 | 2013-08-06 | Pacesetter, Inc. | System and method for estimating cardiac pressure based on cardiac electrical conduction delays using an implantable medical device |
| US7853327B2 (en) * | 2007-04-17 | 2010-12-14 | Cardiac Pacemakers, Inc. | Heart sound tracking system and method |
| US9943234B2 (en) * | 2007-04-17 | 2018-04-17 | Cardiac Pacemakers, Inc. | Using respiration distress manifestations for heart failure detection |
| US8831714B2 (en) * | 2007-05-07 | 2014-09-09 | Cardiac Pacemakers, Inc. | Apparatus and method for heart failure indication based on heart rate, onset and tachyarrhythmia |
| US8825161B1 (en) | 2007-05-17 | 2014-09-02 | Cardiac Pacemakers, Inc. | Acoustic transducer for an implantable medical device |
| US7634318B2 (en) | 2007-06-14 | 2009-12-15 | Cardiac Pacemakers, Inc. | Multi-element acoustic recharging system |
| US9037239B2 (en) | 2007-08-07 | 2015-05-19 | Cardiac Pacemakers, Inc. | Method and apparatus to perform electrode combination selection |
| US8265736B2 (en) | 2007-08-07 | 2012-09-11 | Cardiac Pacemakers, Inc. | Method and apparatus to perform electrode combination selection |
| US8961417B2 (en) * | 2008-01-04 | 2015-02-24 | Texas Heart Institute | Catheter with electrodes for impedance and/or conduction velocity measurement |
| US9078627B2 (en) | 2008-01-04 | 2015-07-14 | Texas Heart Institute | Introducer sheath with electrodes |
| US8273023B2 (en) * | 2009-01-05 | 2012-09-25 | Texas Heart Institute | Introducer sheathe with electrodes |
| US9079033B2 (en) | 2008-01-22 | 2015-07-14 | Cardiac Pacemakers, Inc. | Respiration as a trigger for therapy optimization |
| US8588908B2 (en) * | 2008-02-04 | 2013-11-19 | University Of Virginia Patent Foundation | System, method and computer program product for detection of changes in health status and risk of imminent illness |
| JP5211177B2 (ja) | 2008-02-11 | 2013-06-12 | カーディアック ペースメイカーズ, インコーポレイテッド | 心臓内の調律識別のための血行動態の監視方法 |
| WO2009102640A1 (en) | 2008-02-12 | 2009-08-20 | Cardiac Pacemakers, Inc. | Systems and methods for controlling wireless signal transfers between ultrasound-enabled medical devices |
| CN101939051B (zh) | 2008-02-14 | 2013-07-10 | 心脏起搏器公司 | 用于膈刺激检测的方法和装置 |
| EP2101408B1 (en) * | 2008-03-11 | 2012-05-16 | CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Développement | Floating front-end amplifier and one-wire measuring devices |
| US8744565B2 (en) | 2008-04-30 | 2014-06-03 | Medtronic, Inc. | Multi-frequency impedance monitoring system |
| US9883809B2 (en) * | 2008-05-01 | 2018-02-06 | Earlysense Ltd. | Monitoring, predicting and treating clinical episodes |
| US8401652B2 (en) * | 2008-06-16 | 2013-03-19 | Cvrx, Inc. | Devices and methods for treatment of heart failure and associated conditions |
| US8255046B2 (en) * | 2008-07-31 | 2012-08-28 | Medtronic, Inc. | Detecting worsening heart failure based on impedance measurements |
| US9713701B2 (en) | 2008-07-31 | 2017-07-25 | Medtronic, Inc. | Using multiple diagnostic parameters for predicting heart failure events |
| WO2010030454A1 (en) * | 2008-09-12 | 2010-03-18 | Cardiac Pacemakers, Inc. | Chronically implanted abdominal pressure sensor for continuous ambulatory assessment of renal functions |
| US8469898B2 (en) * | 2008-09-19 | 2013-06-25 | Cardiac Pacemakers, Inc. | Indication-based worsening HF alert |
| WO2010033928A1 (en) * | 2008-09-22 | 2010-03-25 | Cardiac Pacemakers, Inc. | Congestive heart failure decompensation detection |
| WO2010042790A2 (en) | 2008-10-10 | 2010-04-15 | Cardiac Pacemakers, Inc. | Multi-sensor strategy for heart failure patient management |
| EP2334230A1 (en) | 2008-10-10 | 2011-06-22 | Cardiac Pacemakers, Inc. | Systems and methods for determining cardiac output using pulmonary artery pressure measurements |
| WO2010059291A1 (en) | 2008-11-19 | 2010-05-27 | Cardiac Pacemakers, Inc. | Assessment of pulmonary vascular resistance via pulmonary artery pressure |
| EP2375968B1 (en) | 2008-12-15 | 2018-11-14 | Medtronic Monitoring, Inc. | Patient monitoring systems and methods |
| US8033999B2 (en) * | 2008-12-19 | 2011-10-11 | Pacesetter, Inc. | System and method for monitoring myocardial instability |
| US8632473B2 (en) | 2009-01-30 | 2014-01-21 | Medtronic, Inc. | Detecting worsening heart failure based on fluid accumulation with respiratory confirmation |
| US9400872B2 (en) * | 2009-03-05 | 2016-07-26 | Fat Statz Llc | Metrics assessment system for health, fitness and lifestyle behavioral management |
| US8301233B2 (en) * | 2009-03-31 | 2012-10-30 | Medtronic, Inc. | Detecting a condition of a patient using a probability-correlation based model |
| US8958873B2 (en) * | 2009-05-28 | 2015-02-17 | Cardiac Pacemakers, Inc. | Method and apparatus for safe and efficient delivery of cardiac stress augmentation pacing |
| WO2011008749A2 (en) | 2009-07-15 | 2011-01-20 | Cardiac Pacemakers, Inc. | Physiologicl vibration detection in an implanted medical device |
| EP2454697B1 (en) | 2009-07-15 | 2019-05-01 | Cardiac Pacemakers, Inc. | Remote pace detection in an implantable medical device |
| EP2453975B1 (en) | 2009-07-15 | 2016-11-02 | Cardiac Pacemakers, Inc. | Remote sensing in an implantable medical device |
| US8812104B2 (en) * | 2009-09-23 | 2014-08-19 | Cardiac Pacemakers, Inc. | Method and apparatus for automated control of pacing post-conditioning |
| US8271072B2 (en) * | 2009-10-30 | 2012-09-18 | Medtronic, Inc. | Detecting worsening heart failure |
| US20110230771A1 (en) * | 2010-03-19 | 2011-09-22 | Pacesetter, Inc. | Heart failure status monitoring |
| US9420959B2 (en) | 2010-12-15 | 2016-08-23 | Cardiac Pacemakers, Inc. | Detecting heart failure by monitoring the time sequence of physiological changes |
| US10893824B2 (en) | 2010-12-20 | 2021-01-19 | Cardiac Pacemakers, Inc. | Heart failure detection with a sequential classifier |
| US8915869B2 (en) * | 2011-01-10 | 2014-12-23 | Bioguidance Llc | Patient monitoring device |
| US8827930B2 (en) | 2011-01-10 | 2014-09-09 | Bioguidance Llc | System and method for patient monitoring |
| US20120278760A1 (en) * | 2011-04-28 | 2012-11-01 | Medtronic, Inc. | Predictive background data transfer for implantable medical devices |
| HK1201137A1 (en) * | 2011-08-08 | 2015-08-28 | Isonea (Israel) Ltd. | Event sequencing using acoustic respiratory markers and methods |
| US9395234B2 (en) | 2012-12-05 | 2016-07-19 | Cardiocom, Llc | Stabilizing base for scale |
| EP2769668B1 (fr) | 2013-02-26 | 2021-10-13 | Sorin CRM SAS | Ensemble pour le diagnostic adaptatif de l'insuffisance cardiaque moyennant des classifieurs et un arbre de décision booléen |
| US20140330143A1 (en) * | 2013-05-03 | 2014-11-06 | Cardiomems, Inc. | Method and system for treating cardiovascular disease |
| US10143385B2 (en) | 2013-05-20 | 2018-12-04 | Cardiac Pacemakers, Inc. | Methods and apparatus for stratifying risk of heart failure decompensation |
| JP6140369B2 (ja) | 2013-05-20 | 2017-05-31 | カーディアック ペースメイカーズ, インコーポレイテッド | 心不全を検出するための装置 |
| CN105451648A (zh) | 2013-08-05 | 2016-03-30 | 心脏起搏器股份公司 | 基于浅快呼吸指数检测心力衰竭的恶化的系统和方法 |
| EP3065625A1 (en) * | 2013-11-04 | 2016-09-14 | Cardiac Pacemakers, Inc. | Heart failure detection and risk stratification system |
| US10172568B2 (en) | 2014-07-14 | 2019-01-08 | Medtronic, Inc. | Determining prospective risk of heart failure hospitalization |
| US10172593B2 (en) | 2014-09-03 | 2019-01-08 | Earlysense Ltd. | Pregnancy state monitoring |
| US12478285B2 (en) | 2016-08-02 | 2025-11-25 | Medtronic, Inc. | Accelerometer signal change as a measure of patient functional status |
| US10952686B2 (en) | 2016-08-02 | 2021-03-23 | Medtronic, Inc. | Mobile application to prompt physical action to measure physiologic response in implantable device |
| EP4445834A3 (en) | 2017-04-29 | 2024-12-25 | Cardiac Pacemakers, Inc. | Heart failure event rate assessment |
| US11717186B2 (en) | 2019-08-27 | 2023-08-08 | Medtronic, Inc. | Body stability measurement |
| US12575755B2 (en) | 2019-09-27 | 2026-03-17 | Medtronic, Inc. | Determining health condition statuses using subcutaneous impedance measurements |
| EP4356829A3 (en) * | 2020-05-08 | 2024-07-03 | Pacesetter, Inc. | Method and system for heart condition detection using an accelerometer |
| US11602313B2 (en) | 2020-07-28 | 2023-03-14 | Medtronic, Inc. | Determining a fall risk responsive to detecting body position movements |
Family Cites Families (171)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4129125A (en) * | 1976-12-27 | 1978-12-12 | Camin Research Corp. | Patient monitoring system |
| US4422459A (en) | 1980-11-18 | 1983-12-27 | University Patents, Inc. | Electrocardiographic means and method for detecting potential ventricular tachycardia |
| US4754753A (en) * | 1981-05-12 | 1988-07-05 | Medtronic, Inc. | System for sensing electrical depolarization wave signals and their direction |
| US4458691A (en) * | 1982-02-11 | 1984-07-10 | Arrhythmia Research Technology, Inc. | System and method for predicting ventricular tachycardia by adaptive high pass filter |
| US4458692A (en) * | 1982-02-11 | 1984-07-10 | Arrhythmia Research Technology, Inc. | System and method for predicting ventricular tachycardia with a gain controlled high pass filter |
| US4492235A (en) * | 1982-02-11 | 1985-01-08 | Arrhythmia Research Technology, Inc. | System and method for predicting ventricular tachycardia by derivative analysis |
| US4519395A (en) * | 1982-12-15 | 1985-05-28 | Hrushesky William J M | Medical instrument for noninvasive measurement of cardiovascular characteristics |
| US4680708A (en) * | 1984-03-20 | 1987-07-14 | Washington University | Method and apparatus for analyzing electrocardiographic signals |
| US4732157A (en) * | 1986-08-18 | 1988-03-22 | Massachusetts Institute Of Technology | Method and apparatus for quantifying beat-to-beat variability in physiologic waveforms |
| US4777960A (en) * | 1986-08-18 | 1988-10-18 | Massachusetts Institute Of Technology | Method and apparatus for the assessment of autonomic response by broad-band excitation |
| US4930075A (en) * | 1987-07-13 | 1990-05-29 | The Board Of Trustees Of The Leland Stanford Junior University | Technique to evaluate myocardial ischemia from ECG parameters |
| DE3732640C1 (de) * | 1987-09-28 | 1989-05-18 | Alt Eckhard | Medizinisches Geraet zum Ermitteln von physiologischen Funktionsparametern |
| US5014698A (en) * | 1987-10-06 | 1991-05-14 | Leonard Bloom | Method of and system for monitoring and treating a malfunctioning heart |
| US4924875A (en) * | 1987-10-09 | 1990-05-15 | Biometrak Corporation | Cardiac biopotential analysis system and method |
| US5020540A (en) * | 1987-10-09 | 1991-06-04 | Biometrak Corporation | Cardiac biopotential analysis system and method |
| US4957115A (en) * | 1988-03-25 | 1990-09-18 | New England Medical Center Hosp. | Device for determining the probability of death of cardiac patients |
| US4905706A (en) * | 1988-04-20 | 1990-03-06 | Nippon Colin Co., Ltd. | Method an apparatus for detection of heart disease |
| US4960129A (en) * | 1988-12-05 | 1990-10-02 | Trustees Of The University Of Pennsylvania | Methods of observing autonomic neural stimulation and diagnosing cardiac dynamical dysfunction using heartbeat interval data to analyze cardioventilatory interactions |
| US5215099A (en) * | 1989-06-30 | 1993-06-01 | Ralph Haberl | System and method for predicting cardiac arrhythmia utilizing frequency informatiton derived from multiple segments of the late QRS and the ST portion |
| US5509425A (en) * | 1989-10-30 | 1996-04-23 | Feng; Genquan | Arrangement for and method of diagnosing and warning of a heart attack |
| US5042497A (en) * | 1990-01-30 | 1991-08-27 | Cardiac Pacemakers, Inc. | Arrhythmia prediction and prevention for implanted devices |
| US5109862A (en) * | 1990-03-19 | 1992-05-05 | Del Mar Avionics | Method and apparatus for spectral analysis of electrocardiographic signals |
| US5092341A (en) * | 1990-06-18 | 1992-03-03 | Del Mar Avionics | Surface ecg frequency analysis system and method based upon spectral turbulence estimation |
| US5555889A (en) * | 1990-06-20 | 1996-09-17 | Cedars-Sinai Medical Center | Methods for detecting propensity fibrillation |
| US5113869A (en) * | 1990-08-21 | 1992-05-19 | Telectronics Pacing Systems, Inc. | Implantable ambulatory electrocardiogram monitor |
| US5129394A (en) | 1991-01-07 | 1992-07-14 | Medtronic, Inc. | Method and apparatus for controlling heart rate in proportion to left ventricular pressure |
| US5437285A (en) * | 1991-02-20 | 1995-08-01 | Georgetown University | Method and apparatus for prediction of sudden cardiac death by simultaneous assessment of autonomic function and cardiac electrical stability |
| US5265617A (en) | 1991-02-20 | 1993-11-30 | Georgetown University | Methods and means for non-invasive, dynamic tracking of cardiac vulnerability by simultaneous analysis of heart rate variability and T-wave alternans |
| US5148812A (en) * | 1991-02-20 | 1992-09-22 | Georgetown University | Non-invasive dynamic tracking of cardiac vulnerability by analysis of t-wave alternans |
| US5188116A (en) * | 1991-02-28 | 1993-02-23 | Vital Heart Systems, Inc. | Electrocardiographic method and device |
| US5199428A (en) * | 1991-03-22 | 1993-04-06 | Medtronic, Inc. | Implantable electrical nerve stimulator/pacemaker with ischemia for decreasing cardiac workload |
| US5282837A (en) * | 1991-04-12 | 1994-02-01 | Incontrol, Inc. | Atrial defibrillator and method |
| US5161539A (en) * | 1991-05-09 | 1992-11-10 | Physio-Control | Method and apparatus for performing mapping-type analysis including use of limited electrode sets |
| US5181519A (en) * | 1991-05-17 | 1993-01-26 | Caliber Medical Corporation | Device for detecting abnormal heart muscle electrical activity |
| US5217021A (en) * | 1991-07-30 | 1993-06-08 | Telectronics Pacing Systems, Inc. | Detection of cardiac arrhythmias using correlation of a cardiac electrical signals and temporal data compression |
| US5277189A (en) * | 1991-08-16 | 1994-01-11 | Nid, Inc. | Method and apparatus for the measurement and analysis of cardiac rates and amplitude variations |
| EP0532144B1 (de) * | 1991-09-12 | 1999-02-24 | BIOTRONIK Mess- und Therapiegeräte GmbH & Co Ingenieurbüro Berlin | Herztherapiesystem |
| ATE142520T1 (de) * | 1991-11-04 | 1996-09-15 | Cardiac Pacemakers Inc | Implantierbares gerät zur überwachung und stimulation des herzens für diagnose und therapie |
| US5251621A (en) * | 1991-12-18 | 1993-10-12 | Telectronics Pacing Systems, Inc. | Arrhythmia control pacer using skeletal muscle cardiac graft stimulation |
| US5203326A (en) * | 1991-12-18 | 1993-04-20 | Telectronics Pacing Systems, Inc. | Antiarrhythmia pacer using antiarrhythmia pacing and autonomic nerve stimulation therapy |
| US5534015A (en) * | 1992-02-18 | 1996-07-09 | Angeion Corporation | Method and apparatus for generating biphasic waveforms in an implantable defibrillator |
| US5330507A (en) * | 1992-04-24 | 1994-07-19 | Medtronic, Inc. | Implantable electrical vagal stimulation for prevention or interruption of life threatening arrhythmias |
| US5330505A (en) * | 1992-05-08 | 1994-07-19 | Leonard Bloom | System for and method of treating a malfunctioning heart |
| US5285793A (en) * | 1992-05-21 | 1994-02-15 | Regents Of The Univeristy Of Minnesota | Noninvasive detection of rejection in heart transplant patients |
| US5558638A (en) | 1993-04-30 | 1996-09-24 | Healthdyne, Inc. | Patient monitor and support system |
| WO1995003739A1 (en) | 1993-08-03 | 1995-02-09 | Peter Walter Kamen | A method of measuring autonomic activity of a patient |
| DE59300252D1 (de) * | 1993-08-13 | 1995-07-13 | Siemens Ag | Verfahren zur hochauflösenden Spektralanalyse bei mehrkanaligen Beobachtungen. |
| US5411531A (en) * | 1993-09-23 | 1995-05-02 | Medtronic, Inc. | Method and apparatus for control of A-V interval |
| US5431689A (en) * | 1993-09-23 | 1995-07-11 | Pacesetter, Inc. | Implantable stimulation system and method for terminating cardiac arrhythmias |
| US5871505A (en) * | 1993-10-06 | 1999-02-16 | Adams; Theodore P. | Apparatus for generating biphasic waveforms in an implantable defibrillator |
| US6022315A (en) * | 1993-12-29 | 2000-02-08 | First Opinion Corporation | Computerized medical diagnostic and treatment advice system including network access |
| US5713367A (en) * | 1994-01-26 | 1998-02-03 | Cambridge Heart, Inc. | Measuring and assessing cardiac electrical stability |
| US5570696A (en) | 1994-01-26 | 1996-11-05 | Cambridge Heart, Inc. | Method and apparatus for assessing myocardial electrical stability |
| US5419338A (en) * | 1994-02-22 | 1995-05-30 | City Of Hope | Autonomic nervous system testing by bi-variate spectral analysis of heart period and QT interval variability |
| US5645069A (en) * | 1994-05-26 | 1997-07-08 | Lg Electronics Inc. | System for and method of analyzing electrocardiograms employing chaos techniques |
| EP0688578B1 (en) * | 1994-06-24 | 1999-11-10 | Pacesetter AB | Arrhythmia detector |
| EP0688579B1 (en) | 1994-06-24 | 2001-08-22 | St. Jude Medical AB | Device for heart therapy |
| US5724983A (en) * | 1994-08-01 | 1998-03-10 | New England Center Hospitals, Inc. | Continuous monitoring using a predictive instrument |
| US5560368A (en) * | 1994-11-15 | 1996-10-01 | Berger; Ronald D. | Methodology for automated QT variability measurement |
| US5562711A (en) * | 1994-11-30 | 1996-10-08 | Medtronic, Inc. | Method and apparatus for rate-responsive cardiac pacing |
| US5555888A (en) * | 1995-02-27 | 1996-09-17 | Brewer; James E. | Method for automatic, adaptive, active facilitation to access myocardial electrical instability |
| US5655540A (en) * | 1995-04-06 | 1997-08-12 | Seegobin; Ronald D. | Noninvasive method for identifying coronary artery disease utilizing electrocardiography derived data |
| US5609158A (en) * | 1995-05-01 | 1997-03-11 | Arrhythmia Research Technology, Inc. | Apparatus and method for predicting cardiac arrhythmia by detection of micropotentials and analysis of all ECG segments and intervals |
| US5743267A (en) | 1995-10-19 | 1998-04-28 | Telecom Medical, Inc. | System and method to monitor the heart of a patient |
| US5758652A (en) | 1995-10-19 | 1998-06-02 | Nikolic; Serjan D. | System and method to measure the condition of a patients heart |
| US5836987A (en) | 1995-11-15 | 1998-11-17 | Cardiac Pacemakers, Inc. | Apparatus and method for optimizing cardiac performance by determining the optimal timing interval from an accelerometer signal |
| US6035233A (en) * | 1995-12-11 | 2000-03-07 | Intermedics Inc. | Implantable medical device responsive to heart rate variability analysis |
| US5749900A (en) * | 1995-12-11 | 1998-05-12 | Sulzer Intermedics Inc. | Implantable medical device responsive to heart rate variability analysis |
| US5819007A (en) * | 1996-03-15 | 1998-10-06 | Siemens Medical Systems, Inc. | Feature-based expert system classifier |
| AU2804397A (en) | 1996-04-23 | 1997-11-12 | Zymed Medical Instrumentation, Inc. | Process for monitoring patients with chronic congestive heart failure |
| US5792197A (en) * | 1996-04-29 | 1998-08-11 | Nappholz; Tibor A. | Implanted cardiac device with means for classifying patient condition |
| US5891176A (en) | 1996-05-09 | 1999-04-06 | Pacesetter, Inc. | System and method for providing hemodynamically optimal pacing |
| US5976082A (en) | 1996-06-17 | 1999-11-02 | Smithkline Beecham Corporation | Method for identifying at risk patients diagnosed with congestive heart failure |
| US5931834A (en) * | 1996-10-15 | 1999-08-03 | Eclipse Surgical Technologies, Inc. | Method for non-synchronous laser-assisted myocardial revascularization |
| US5785702A (en) * | 1996-10-15 | 1998-07-28 | Eclipse Surgical Technologies, Inc. | Method for non-synchronous laser-assisted transmyocardial revascularization |
| US5713938A (en) | 1996-11-12 | 1998-02-03 | Pacesetter, Inc. | Fuzzy logic expert system for an implantable cardiac device |
| US5778881A (en) * | 1996-12-04 | 1998-07-14 | Medtronic, Inc. | Method and apparatus for discriminating P and R waves |
| US5957861A (en) | 1997-01-31 | 1999-09-28 | Medtronic, Inc. | Impedance monitor for discerning edema through evaluation of respiratory rate |
| US5876353A (en) | 1997-01-31 | 1999-03-02 | Medtronic, Inc. | Impedance monitor for discerning edema through evaluation of respiratory rate |
| US5772604A (en) * | 1997-03-14 | 1998-06-30 | Emory University | Method, system and apparatus for determining prognosis in atrial fibrillation |
| US5788643A (en) | 1997-04-22 | 1998-08-04 | Zymed Medical Instrumentation, Inc. | Process for monitoring patients with chronic congestive heart failure |
| US5974340A (en) | 1997-04-29 | 1999-10-26 | Cardiac Pacemakers, Inc. | Apparatus and method for monitoring respiratory function in heart failure patients to determine efficacy of therapy |
| US5868680A (en) * | 1997-09-23 | 1999-02-09 | The Regents Of The University Of California | Quantitative characterization of fibrillatory spatiotemporal organization |
| US6129744A (en) | 1997-12-04 | 2000-10-10 | Vitatron Medical, B.V. | Cardiac treatment system and method for sensing and responding to heart failure |
| US6070100A (en) | 1997-12-15 | 2000-05-30 | Medtronic Inc. | Pacing system for optimizing cardiac output and determining heart condition |
| SE9800040D0 (sv) | 1998-01-09 | 1998-01-09 | Pacesetter Ab | A heart stimulator |
| US5935081A (en) | 1998-01-20 | 1999-08-10 | Cardiac Pacemakers, Inc. | Long term monitoring of acceleration signals for optimization of pacing therapy |
| US6148228A (en) | 1998-03-05 | 2000-11-14 | Fang; Dan Oun | System and method for detecting and locating heart disease |
| US6021351A (en) | 1998-05-11 | 2000-02-01 | Cardiac Pacemakers, Inc. | Method and apparatus for assessing patient well-being |
| US6539249B1 (en) | 1998-05-11 | 2003-03-25 | Cardiac Pacemakers, Inc. | Method and apparatus for assessing patient well-being |
| US6045513A (en) | 1998-05-13 | 2000-04-04 | Medtronic, Inc. | Implantable medical device for tracking patient functional status |
| US6301499B1 (en) | 1998-06-08 | 2001-10-09 | Cardiac Pacemakers, Inc. | Heart rate variability as an indicator of exercise capacity |
| FR2780290B1 (fr) | 1998-06-26 | 2000-09-22 | Ela Medical Sa | Dispositif medical implantable actif asservi tel que stimulateur cardiaque, defibrillateur et/ou cardioverteur, notamment de type multisites |
| US6104949A (en) | 1998-09-09 | 2000-08-15 | Vitatron Medical, B.V. | Medical device |
| US6067466A (en) * | 1998-11-18 | 2000-05-23 | New England Medical Center Hospitals, Inc. | Diagnostic tool using a predictive instrument |
| US6155267A (en) | 1998-12-31 | 2000-12-05 | Medtronic, Inc. | Implantable medical device monitoring method and system regarding same |
| US6473640B1 (en) | 1999-01-25 | 2002-10-29 | Jay Erlebacher | Implantable device and method for long-term detection and monitoring of congestive heart failure |
| US6112116A (en) * | 1999-02-22 | 2000-08-29 | Cathco, Inc. | Implantable responsive system for sensing and treating acute myocardial infarction |
| US6454707B1 (en) | 1999-03-08 | 2002-09-24 | Samuel W. Casscells, III | Method and apparatus for predicting mortality in congestive heart failure patients |
| US6110109A (en) * | 1999-03-26 | 2000-08-29 | Biosignia, Inc. | System and method for predicting disease onset |
| US6128526A (en) * | 1999-03-29 | 2000-10-03 | Medtronic, Inc. | Method for ischemia detection and apparatus for using same |
| US6115627A (en) * | 1999-04-09 | 2000-09-05 | Pacesetter, Inc. | Intracardiac predictor of imminent arrhythmia |
| US6190324B1 (en) | 1999-04-28 | 2001-02-20 | Medtronic, Inc. | Implantable medical device for tracking patient cardiac status |
| US6285907B1 (en) * | 1999-05-21 | 2001-09-04 | Cardiac Pacemakers, Inc. | System providing ventricular pacing and biventricular coordination |
| US6512949B1 (en) | 1999-07-12 | 2003-01-28 | Medtronic, Inc. | Implantable medical device for measuring time varying physiologic conditions especially edema and for responding thereto |
| US6360123B1 (en) | 1999-08-24 | 2002-03-19 | Impulse Dynamics N.V. | Apparatus and method for determining a mechanical property of an organ or body cavity by impedance determination |
| US6272377B1 (en) * | 1999-10-01 | 2001-08-07 | Cardiac Pacemakers, Inc. | Cardiac rhythm management system with arrhythmia prediction and prevention |
| US6459929B1 (en) | 1999-11-04 | 2002-10-01 | Cardiac Pacemakers, Inc. | Implantable cardiac rhythm management device for assessing status of CHF patients |
| US6275727B1 (en) | 1999-11-04 | 2001-08-14 | Cardiac Pacemakers, Inc. | Implantable cardiac rhythm management device for assessing status of CHF patients |
| US6600949B1 (en) | 1999-11-10 | 2003-07-29 | Pacesetter, Inc. | Method for monitoring heart failure via respiratory patterns |
| US6409675B1 (en) | 1999-11-10 | 2002-06-25 | Pacesetter, Inc. | Extravascular hemodynamic monitor |
| US6491639B1 (en) | 1999-11-10 | 2002-12-10 | Pacesetter, Inc. | Extravascular hemodynamic sensor |
| US6480733B1 (en) | 1999-11-10 | 2002-11-12 | Pacesetter, Inc. | Method for monitoring heart failure |
| US6336903B1 (en) * | 1999-11-16 | 2002-01-08 | Cardiac Intelligence Corp. | Automated collection and analysis patient care system and method for diagnosing and monitoring congestive heart failure and outcomes thereof |
| US6277078B1 (en) | 1999-11-19 | 2001-08-21 | Remon Medical Technologies, Ltd. | System and method for monitoring a parameter associated with the performance of a heart |
| US6752765B1 (en) | 1999-12-01 | 2004-06-22 | Medtronic, Inc. | Method and apparatus for monitoring heart rate and abnormal respiration |
| US6497655B1 (en) | 1999-12-17 | 2002-12-24 | Medtronic, Inc. | Virtual remote monitor, alert, diagnostics and programming for implantable medical device systems |
| US6471645B1 (en) | 1999-12-30 | 2002-10-29 | Medtronic, Inc. | Communications system for an implantable device and a drug dispenser |
| US6328699B1 (en) * | 2000-01-11 | 2001-12-11 | Cedars-Sinai Medical Center | Permanently implantable system and method for detecting, diagnosing and treating congestive heart failure |
| DE60131041T2 (de) | 2000-01-19 | 2008-07-31 | Pacesetter, Inc., Sylmar | Implantierbare Herzvorrichtung zur Überwachung der Verschlechterung oder Verbesserung von Herzerkrankungen |
| US6643548B1 (en) | 2000-04-06 | 2003-11-04 | Pacesetter, Inc. | Implantable cardiac stimulation device for monitoring heart sounds to detect progression and regression of heart disease and method thereof |
| US6371922B1 (en) | 2000-04-07 | 2002-04-16 | Cardiac Pacemakers, Inc. | Method for measuring baroreflex sensitivity and therapy optimization in heart failure patients |
| US6473646B2 (en) * | 2000-04-18 | 2002-10-29 | Cardiac Pacemakers, Inc. | Method and apparatus for assessing cardiac functional status |
| US6456880B1 (en) | 2000-05-01 | 2002-09-24 | Pacesetter, Inc. | Implantable cardiac stimulation device for and method of monitoring progression or regression of a patient's heart condition by monitoring ventricular repolarization interval dispersion |
| US6589188B1 (en) | 2000-05-05 | 2003-07-08 | Pacesetter, Inc. | Method for monitoring heart failure via respiratory patterns |
| US6572557B2 (en) | 2000-05-09 | 2003-06-03 | Pacesetter, Inc. | System and method for monitoring progression of cardiac disease state using physiologic sensors |
| WO2001087410A2 (en) * | 2000-05-15 | 2001-11-22 | Pacesetter, Inc. | Cardiac stimulation devices and methods for measuring impedances associated with the left side of the heart |
| US6669631B2 (en) | 2000-06-14 | 2003-12-30 | Medtronic, Inc. | Deep computing applications in medical device systems |
| US6424865B1 (en) * | 2000-07-13 | 2002-07-23 | Cardiac Pacemakers, Inc. | Ventricular conduction delay trending system and method |
| US6459934B1 (en) | 2000-07-21 | 2002-10-01 | Cardiac Pacemakers, Inc. | Estimate of efficiency using acceleration-heart rate ratio |
| US6454719B1 (en) | 2000-08-01 | 2002-09-24 | Pacesetter, Inc. | Apparatus and method for diagnosis of cardiac disease using a respiration monitor |
| US6449509B1 (en) | 2000-08-30 | 2002-09-10 | Pacesetter, Inc. | Implantable stimulation device having synchronous sampling for a respiration sensor |
| US6473647B1 (en) | 2000-10-18 | 2002-10-29 | Pacesetter, Inc. | Implantable cardiac stimulation device for and method of monitoring progression or regression of heart disease by monitoring evoked response features |
| WO2002040096A1 (en) | 2000-11-17 | 2002-05-23 | Medtronic, Inc. | Method and apparatus for monitoring heart rate and abnormal respiration |
| US6741885B1 (en) | 2000-12-07 | 2004-05-25 | Pacesetter, Inc. | Implantable cardiac device for managing the progression of heart disease and method |
| IT1318370B1 (it) * | 2000-12-21 | 2003-08-25 | Tonino Bombardini | Metodo e dispositivo per la diagnosi e la terapia dello scompensocardiaco cronico. |
| US6738667B2 (en) * | 2000-12-28 | 2004-05-18 | Medtronic, Inc. | Implantable medical device for treating cardiac mechanical dysfunction by electrical stimulation |
| US6438408B1 (en) | 2000-12-28 | 2002-08-20 | Medtronic, Inc. | Implantable medical device for monitoring congestive heart failure |
| EP1233075A3 (en) * | 2001-02-15 | 2003-01-08 | Whitehead Institute For Biomedical Research | BDNF polymorphism and association with bipolar disorder |
| US6668188B2 (en) * | 2001-04-25 | 2003-12-23 | Cardiac Pacemakers, Inc. | Determination of long-term condition of cardiac patients |
| US6580946B2 (en) | 2001-04-26 | 2003-06-17 | Medtronic, Inc. | Pressure-modulated rate-responsive cardiac pacing |
| US6641542B2 (en) | 2001-04-30 | 2003-11-04 | Medtronic, Inc. | Method and apparatus to detect and treat sleep respiratory events |
| US6488677B1 (en) | 2001-05-10 | 2002-12-03 | Thermal Technologies, Inc. | System for quantifying edema |
| GB0114659D0 (en) | 2001-06-15 | 2001-08-08 | Finsbury Dev Ltd | Device |
| US6804555B2 (en) * | 2001-06-29 | 2004-10-12 | Medtronic, Inc. | Multi-site ventricular pacing system measuring QRS duration |
| US6760622B2 (en) * | 2001-07-03 | 2004-07-06 | Pacesetter, Inc. | Implantable multi-chamber cardiac stimulation device with sensing vectors |
| US6668194B2 (en) * | 2001-07-16 | 2003-12-23 | Medtronic, Inc. | Method and apparatus for monitoring conduction times in a bi-chamber pacing system |
| US6595927B2 (en) | 2001-07-23 | 2003-07-22 | Medtronic, Inc. | Method and system for diagnosing and administering therapy of pulmonary congestion |
| US7191000B2 (en) * | 2001-07-31 | 2007-03-13 | Cardiac Pacemakers, Inc. | Cardiac rhythm management system for edema |
| DE10148440A1 (de) | 2001-10-01 | 2003-04-17 | Inflow Dynamics Inc | Vorrichtung zum Überwachen eines Blutstaus im Herzen |
| US8777851B2 (en) | 2001-10-01 | 2014-07-15 | Medtronic, Inc. | Congestive heart failure monitor and ventilation measuring implant |
| US6561984B1 (en) | 2001-10-16 | 2003-05-13 | Pacesetter, Inc. | Assessing heart failure status using morphology of a signal representative of arterial pulse pressure |
| US6575912B1 (en) | 2001-10-16 | 2003-06-10 | Pacesetter, Inc. | Assessing heart failure status using morphology of a signal representative of arterial pulse pressure |
| US6795732B2 (en) * | 2001-10-30 | 2004-09-21 | Medtronic, Inc. | Implantable medical device employing sonomicrometer output signals for detection and measurement of cardiac mechanical function |
| US6980851B2 (en) * | 2001-11-15 | 2005-12-27 | Cardiac Pacemakers, Inc. | Method and apparatus for determining changes in heart failure status |
| US6959214B2 (en) * | 2001-11-28 | 2005-10-25 | Medtronic, Inc. | Implantable medical device for measuring mechanical heart function |
| FR2833177B1 (fr) | 2001-12-07 | 2004-06-04 | Ela Medical Sa | Dispositif medical actif comprenant des moyens perfectionnes de discrimination des phases d'eveil et de sommeil |
| US6645153B2 (en) | 2002-02-07 | 2003-11-11 | Pacesetter, Inc. | System and method for evaluating risk of mortality due to congestive heart failure using physiologic sensors |
| US6961615B2 (en) * | 2002-02-07 | 2005-11-01 | Pacesetter, Inc. | System and method for evaluating risk of mortality due to congestive heart failure using physiologic sensors |
| US6928324B2 (en) * | 2002-02-14 | 2005-08-09 | Pacesetter, Inc. | Stimulation device for sleep apnea prevention, detection and treatment |
| SE0200921D0 (sv) | 2002-03-25 | 2002-03-25 | St Jude Medical | A heart monitoring device, a system including such a device and a manner of using the system |
| US7386346B2 (en) * | 2002-04-22 | 2008-06-10 | Medtronic, Inc. | Controlled and modulated high power racing combined with intracardiac pressure monitoring feedback system utilizing the chronicle implantable hemodynamic monitoring (IHM) and calculated EPAD |
| US7164948B2 (en) | 2002-04-22 | 2007-01-16 | Medtronic, Inc. | Cardiac output measurement using dual oxygen sensors in right and left ventricles |
| US6969369B2 (en) | 2002-04-22 | 2005-11-29 | Medtronic, Inc. | Implantable drug delivery system responsive to intra-cardiac pressure |
| US7113825B2 (en) | 2002-05-03 | 2006-09-26 | Cardiac Pacemakers, Inc. | Method and apparatus for detecting acoustic oscillations in cardiac rhythm |
| US7400928B2 (en) | 2002-10-11 | 2008-07-15 | Cardiac Pacemakers, Inc. | Methods and devices for detection of context when addressing a medical condition of a patient |
| US7313434B2 (en) | 2002-11-25 | 2007-12-25 | Regents Of The University Of Minnesota | Impedance monitoring for detecting pulmonary edema and thoracic congestion |
| US7986994B2 (en) | 2002-12-04 | 2011-07-26 | Medtronic, Inc. | Method and apparatus for detecting change in intrathoracic electrical impedance |
| US7787946B2 (en) | 2003-08-18 | 2010-08-31 | Cardiac Pacemakers, Inc. | Patient monitoring, diagnosis, and/or therapy systems and methods |
| US8428717B2 (en) | 2003-10-14 | 2013-04-23 | Medtronic, Inc. | Method and apparatus for monitoring tissue fluid content for use in an implantable cardiac device |
| US9986502B2 (en) | 2015-12-15 | 2018-05-29 | Mitsubishi Electric Research Laboratories, Inc. | Distributed sleep management for battery powered multi-hop heterogeneous wireless network |
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| US7127290B2 (en) | 2006-10-24 |
| AU2003261399A1 (en) | 2004-02-23 |
| WO2004012815A1 (en) | 2004-02-12 |
| US20030055461A1 (en) | 2003-03-20 |
| JP2005534406A (ja) | 2005-11-17 |
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