JP4499159B2 - 関節置換術用の金属製軸受 - Google Patents
関節置換術用の金属製軸受 Download PDFInfo
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- JP4499159B2 JP4499159B2 JP2007536901A JP2007536901A JP4499159B2 JP 4499159 B2 JP4499159 B2 JP 4499159B2 JP 2007536901 A JP2007536901 A JP 2007536901A JP 2007536901 A JP2007536901 A JP 2007536901A JP 4499159 B2 JP4499159 B2 JP 4499159B2
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- bearing surface
- metal bearing
- prosthesis
- hardness
- hard metal
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Landscapes
- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Transplantation (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
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- Cardiology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Non-Disconnectible Joints And Screw-Threaded Joints (AREA)
Description
適用なし
連邦政府がスポンサーとなる研究または開発に関する申告
適用なし
マイクロフィッシュ付録の参照
適用なし
整形外科用関節プロテーゼは、股関節、膝関節、足関節、または肩甲関節などの、罹患した関節を置換するために使用される。整形外科用関節プロテーゼは、自然の関節の関節面によって与えられる関節運動と類似の関節運動を可能にする軸受面を含む。
本発明は、以下に説明する予期しない結果を含めて、整形外科用インプラント用途に現在認可されている材料を用いて可能な、最も摩耗が少ない軸受継手を見出すことを目標にWright Medicalによって開始された摩耗試験の結果として得られたものである。硬度差MOM軸受((differential hardness MON bearing)を試験する前に、Wright Medicalは摩耗率を決定するためにCOM軸受の組合せを試験した。予期されたように、Wrightは、公表されたMOM摩耗率に比較してCOM股関節プロテーゼの摩耗率が小さいことを観察した。COM股関節プロテーゼは、通常、セラミック軸受面と金属軸受面との間に約4倍の硬度差を有することに注目して、本発明者は、硬度差軸受(DHB)が摩耗性能を改善できる能力の下限が存在するという仮説を立てた。摩耗改善に関する硬度差の限界はこれまで決められていなかった。硬度についての多くの摩耗モデルには、記述式中に硬度についてただ1つの値しか含まず、したがって異なる硬度を有する軸受を用いる効果を考慮に入れることができない。
2.鋳造CoCrヘッド/鋳造CoCrカップ(ヘッドとカップは共にASTM F75に従っており、ロックウェル硬度(Rc)=25〜30である。硬度差=1.0倍、n=3である。)
3.展伸用CoCrヘッド/鋳造−熱処理CoCrカップ(ASTM1537ヘッド/ASTM F75カップであり、ヘッドについてはロックウェル硬度(Rc)=42、カップについてはロックウェル硬度(Rc)=25である。硬度差=1.68倍、n=3である。)
4.熱処理展伸用CoCrヘッド/鋳造−熱処理CoCrカップ(ASTM F1537HTヘッド/ASTM F75カップであり、ヘッドについてはロックウェル硬度(Rc)=50〜52、カップについてはロックウェル硬度(Rc)=25である。硬度差=2.08倍、n=2である。)
摩耗試験は、SHORE WESTERN OBM摩耗試験機(90%ウシ血清溶液、トリプルピークPaulプロフィール(1Hzで最大2000N)、逆位置の試験片(ヘッドを上に/シェルを下に))を用いて、股関節摩耗試験用の典型的なWMT摩耗試験プロトコルに対して行われた。試験片は質量損失を測定するために特定の間隔で計量された。試験片はすべて直径が54mmであった。上記のグループ1で説明した材料の組合せは、現在、Wright MedicalのCONSERVE(登録商標)PLUS MOM股関節プロテーゼに使用されている。グループ1の組合せは、金属対ポリマーおよび競合的MOMプロテーゼに比較すれば少ない摩耗量を生じた。しかし上述のように、一部の外科医は、摩耗粉からの金属イオン放出による潜在的な副作用のためにMOMプロテーゼを使用することに関して依然として懸念しており、したがって、摩耗をさらに低減することに関心がある。
Claims (24)
- コバルトクロム合金の軟質金属軸受面を有し、前記軟質金属軸受面がロックウェル硬度約20以上を有する第1のコンポーネントと、
コバルトクロム合金の硬質金属軸受面を有し、前記硬質金属軸受面が前記軟質金属軸受面よりもロックウェル硬度約15以上大きい硬度を有する第2のコンポーネントと、
互いに関節運動するように構成された前記軟質金属軸受面および前記硬質金属軸受面と
を含む整形外科用関節プロテーゼ。 - 前記軟質金属軸受面に対する前記硬質金属軸受面の硬度差が約1.5以上である、請求項1に記載のプロテーゼ。
- 前記軟質金属軸受面に対する前記硬質金属軸受面の硬度差が約1.5と約3との間である、請求項1に記載のプロテーゼ。
- 前記硬質金属軸受面が前記軟質金属軸受面よりもロックウェル硬度約40以下、より硬質である、請求項1に記載のプロテーゼ。
- 前記硬質金属軸受面がロックウェル硬度約40とロックウェル硬度約60との間の硬度を有する、請求項1に記載のプロテーゼ。
- 前記コンポーネントの一方が実質的に凸形の軸受面を有し、前記コンポーネントの他方が、前記凸形軸受面を有する前記コンポーネントをその内側に受け入れるように構成された実質的に凹形の軸受面を有する、請求項1に記載のプロテーゼ。
- 前記軟質金属軸受面が凹形であり、前記硬質金属軸受面が凸形である、請求項6に記載のプロテーゼ。
- 前記軟質金属軸受面の前記コバルトクロム合金がASTM F75に従っており、前記硬質金属軸受面の前記コバルトクロム合金がASTM 1537に従っている、請求項1に記載のプロテーゼ。
- 前記硬質金属軸受面の硬度を高めるように前記硬質金属軸受面が熱処理されている、請求項8に記載のプロテーゼ。
- 軟質金属軸受面を有し、前記軟質金属軸受面がコバルトクロム合金から形成された寛骨臼カップと、
大腿骨頭部分を有し、前記大腿骨頭部分が硬質金属軸受面を有し、前記硬質金属軸受面がコバルトクロム合金から形成された大腿骨コンポーネントと
を含み、
前記硬質金属軸受面は、前記軟質金属軸受面よりもロックウェル硬度約15以上大きい硬度を有し、
前記軟質金属軸受面および前記硬質金属軸受面は互いに関節運動するように構成された、
股関節プロテーゼ。 - 前記軟質金属軸受面に対する前記硬質金属軸受面の硬度差が約1.5以上である、請求項10に記載のプロテーゼ。
- 前記軟質金属軸受面に対する前記硬質金属軸受面の硬度差が約1.5と約3との間である、請求項10に記載のプロテーゼ。
- 前記硬質金属軸受面が前記軟質金属軸受面よりもロックウェル硬度約40以下、より硬質である、請求項10に記載のプロテーゼ。
- 前記硬質金属軸受面がロックウェル硬度約40とロックウェル硬度約60との間の硬度を有する、請求項10に記載のプロテーゼ。
- 前記軟質金属軸受面の前記コバルトクロム合金がASTM F75に従っており、前記硬質金属軸受面の前記コバルトクロム合金がASTM 1537に従っている、請求項10に記載のプロテーゼ。
- 前記硬質金属軸受面の硬度を高めるように前記硬質金属軸受面が熱処理されている、請求項15に記載のプロテーゼ。
- ネック部窪みを中に有する球面軸受部材と、
近位端に隣接する窪みを有する大腿骨ステムと、
近位端が前記球面軸受部材の前記ネック部窪みに固定的に係合するように構成され、遠位端が前記ステムの前記窪みに固定的に係合するように構成されたモジュール式ネック部材と、
前記球面軸受部材と共に関節運動するように構成された凹形の軸受面を有する寛骨臼インプラントと
を含む股関節プロテーゼであって、
前記球面軸受部材および前記凹形の軸受面のうちの一方がコバルトクロム合金の軟質金属軸受面を含み、前記軟質金属軸受面はロックウェル硬度約20以上の硬度を有し、
前記球面軸受部材と前記凹形の軸受面との間に硬度差が存在し、前記股関節プロテーゼの摩耗を低減することができるように、前記球面軸受部材および前記凹形の軸受面のうちの前記他方が、コバルトクロム合金の硬質金属軸受面を含み、前記硬質金属軸受面は前記軟質金属軸受面よりもロックウェル硬度約15以上大きい硬度を有する、股関節プロテーゼ。 - 前記軟質金属軸受面に対する前記硬質金属軸受面の硬度差が約1.5以上である、請求項17に記載のプロテーゼ。
- 前記軟質金属軸受面に対する前記硬質金属軸受面の硬度差が約1.5と約3との間である、請求項17に記載のプロテーゼ。
- 前記硬質金属軸受面が前記軟質金属軸受面よりもロックウェル硬度約40以下、より硬質である、請求項17に記載のプロテーゼ。
- 前記硬質金属軸受面がロックウェル硬度約40とロックウェル硬度約60との間の硬度を有する、請求項17に記載のプロテーゼ。
- 前記球面軸受部材が前記硬質金属軸受面を含み、前記凹形の軸受部材が前記軟質金属軸受面を含む、請求項17に記載のプロテーゼ。
- 前記軟質金属軸受面の前記コバルトクロム合金がASTM F75に従っており、前記硬質金属軸受面の前記コバルトクロム合金がASTM 1537に従っている、請求項17に記載のプロテーゼ。
- 前記硬質金属軸受面の硬度を高めるように前記硬質金属軸受面が熱処理されている、請求項17に記載のプロテーゼ。
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US10/965,491 US7361194B2 (en) | 2004-10-14 | 2004-10-14 | Metallic bearings for joint replacement |
PCT/US2005/036899 WO2006044576A1 (en) | 2004-10-14 | 2005-10-13 | Metallic bearings for joint replacement |
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ATE449582T1 (de) | 2009-12-15 |
CN100551340C (zh) | 2009-10-21 |
US7867281B2 (en) | 2011-01-11 |
EP1830750A1 (en) | 2007-09-12 |
WO2006044576A1 (en) | 2006-04-27 |
US20060085079A1 (en) | 2006-04-20 |
EP1830750B1 (en) | 2009-11-25 |
US20080200988A1 (en) | 2008-08-21 |
KR20070083670A (ko) | 2007-08-24 |
KR101118800B1 (ko) | 2012-03-20 |
CN101039636A (zh) | 2007-09-19 |
US7361194B2 (en) | 2008-04-22 |
AU2005295707B2 (en) | 2012-03-08 |
DE602005017937D1 (de) | 2010-01-07 |
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