JP4481628B2 - Drop-off detection device - Google Patents

Description

  The present invention relates to a dropout detection device that detects a dropout of an injection needle that is punctured into a blood vessel near the surface of a human body in order to inject a chemical solution, and in particular, to drop the injection needle that is connected to the chemical solution injection device with an extension tube. The present invention relates to a dropout detection device to detect.

  Currently, there are CT (Computed Tomography) scanner, MRI (Magnetic Resonance Imaging) device, PET (Positron Emission Tomography) device, ultrasound diagnostic device, etc. as medical devices for imaging tomographic images of subjects. Examples of medical devices for imaging include an angio device and an MRA (MR Angio) device.

  When using the medical device as described above, a chemical solution such as a contrast medium or physiological saline may be injected into the subject, and a chemical solution injection device that automatically executes this injection has also been put into practical use. In this chemical solution injection device, for example, a pump device in which an injection needle is connected by an extension tube is used, and the chemical solution is injected into a blood vessel near the surface of the human body by the injection needle.

However, when a chemical solution is injected by such a chemical solution injection device, even if the injection needle drops from the blood vessel and the chemical solution leaks subcutaneously, it is difficult for the operator to quickly recognize this. In order to solve such a problem, various drop-off detection devices that detect drop-off of an injection needle punctured into a blood vessel near the surface of a human body to inject a chemical solution have been proposed (for example, Patent Documents 1 to 8). reference).
USP 6,408,204 USP 5,964,703 USP 5,947,910 USP 6,375,624 USP 5,954,668 USP 5,334,141 USP 4,647,281 USP 4,877,034

  The drop detection devices of Patent Documents 1 to 3 described above detect the leakage of the chemical liquid from the impedance change of the human body surface, and the drop detection devices of Patent Documents 4 to 7 detect the leakage of the chemical liquid from the temperature change of the human body tissue. The drop-off detection device of Patent Document 8 detects leakage of a chemical solution from a change in optical characteristics of blood. However, any of these dropout detection devices requires a special sensor and has a complicated structure, and the detection accuracy is significantly lowered due to the influence of disturbance.

  The present invention has been made in view of the above-described problems, and an object of the present invention is to provide a drop-off detection device that has a simple structure and has a small decrease in detection accuracy due to disturbance.

The first falling detection device of the present invention, there is provided a dropout detector for detecting falling of the injection needle to be pierced into a blood vessel near the surface of the human body in order to inject the liquid, the laser diode, the photodetector element, the flow rate detection Means, start input means, speed storage means, end input means, drop-off determination means, and warning notification means . The laser diode irradiates the blood vessel in which the injection needle is inserted with a laser beam, and the light detection element detects the laser beam reflected by the blood moving through the blood vessel. The flow velocity detection means detects the blood flow velocity from the detection result of the light detection element. In the start input means, data on the start of injection of the chemical solution is input. The velocity storage means stores the blood flow velocity before the input of the start of injection as a natural velocity, and the end input means inputs the end of the injection of the drug solution. The dropout judging means judges the dropout of the injection needle when the difference between the blood flow velocity and the natural velocity falls below a predetermined allowable range after the start of injection and before the end of injection. If the change is not detected, a warning notification means you notification output falling warning.

  The various means referred to in the present invention need only be formed so as to realize the function. For example, dedicated hardware that exhibits a predetermined function, a data processing apparatus provided with a predetermined function by a computer program It can be realized as a predetermined function implemented in the data processing apparatus by a computer program, a combination thereof, or the like.

  In addition, the various means referred to in the present invention do not have to be individually independent, a plurality of means are formed as one member, and a certain means is a part of another means. It is also possible that a part of the means overlaps with a part of the other means.

In the dropout detection device of the present invention, the blood vessel into which the injection needle is inserted is irradiated with a laser beam, the laser beam reflected by the blood moving through the blood vessel is detected, the blood flow velocity is detected from the detection result, and the blood When the difference between the blood flow velocity and the natural velocity falls below the predetermined tolerance after the input of the start of injection and before the input of the end of injection, the dropout of the injection needle is determined. If this is done, a dropout warning is output as a notification, so that the dropout of the injection needle can be notified with a simple structure without being affected by disturbance.

[Configuration of the embodiment]
Embodiments of the present invention will be described below with reference to the drawings. The fluoroscopic imaging system 1000 according to the present embodiment includes a chemical liquid injector 100, a chemical syringe 200, an MRI apparatus 300 that is a fluoroscopic imaging apparatus, and a dropout detection unit 400. The MRI apparatus 300 will be described in detail later. Then, a chemical solution such as a contrast medium is injected from the chemical solution syringe 200 by the chemical solution injection device 100 into a subject (not shown) who takes a fluoroscopic image.

  As shown in FIG. 3, the MRI apparatus 300 includes a fluoroscopic imaging unit 301 and an imaging control unit 302 that are imaging execution mechanisms. The fluoroscopic imaging unit 301 and the imaging control unit 302 are wired via a communication network 303. It is connected. The fluoroscopic imaging unit 301 captures a fluoroscopic image from the subject, and the imaging control unit 302 controls the operation of the fluoroscopic imaging unit 301.

  The imaging control unit 302 includes a computer system having a detection device main body 303, a liquid crystal display 304, and a keyboard 305, and also executes display output of tomographic images captured by the fluoroscopic imaging unit 301. In order to simplify the illustration in FIG. 3, both the chemical injection device 100 and the imaging control unit 302 are located in the vicinity of the fluoroscopic imaging unit 301, but in the actual site, the chemical injection is in the vicinity of the fluoroscopic imaging unit 301. Only the apparatus 100 is arranged, and the imaging control unit 302 is installed in a separate room.

  As shown in FIG. 5, the chemical syringe 200 includes a cylinder member 210 and a piston member 220, and the piston member 220 is slidably inserted into the cylinder member 210. The cylinder member 210 has a cylindrical hollow main body portion 211, and a conduit portion 212 is formed on the closed end surface of the main body portion 211.

  The end surface of the main body 211 of the cylinder member 210 is opened, and the piston member 220 is inserted into the main body 211 from this opening. A cylinder flange 213 is formed on the outer periphery of the cylinder member 210, and a piston flange 221 is formed on the outer periphery of the piston member 220.

  As shown in FIG. 4, the chemical injection device 100 according to the present embodiment includes an injection control unit 101 and an injection head 110 that is an injection device main body, which are separately formed. The injection control unit 101 and the injection head 110 are different from each other. The communication cable 102 is wired. The injection head 110 drives the chemical syringe 200 to be attached to inject the chemical into the subject, and the injection control unit 101 controls the operation of the injection head 110.

  Therefore, as shown in FIG. 2, the injection control unit 101 includes a computer unit 120, and is also wired to the imaging control unit 302 of the MRI apparatus 300 via a communication network 304. As shown in FIG. 4, the injection control unit 101 includes an operation panel 103, a touch panel 104, a speaker unit 105, and the like arranged on the front surface of the main body housing 106, and a separate controller unit 107 is connected by wire with a connection connector 108. Has been.

  The injection head 110 is attached to the upper end of the caster stand 111 by a movable arm 112. As shown in FIG. 5, a chemical syringe 200 is detachably attached to the upper surface of the head main body 113 that is the main body of the injection apparatus. A semi-cylindrical groove-like recess 114 is formed.

  A cylinder holding mechanism 116 that removably holds the cylinder flange 211 of the chemical syringe 200 is formed as a deformed part at the front part of the concave part 114, and the piston flange 221 is held behind the concave part 114 to slide. A chemical solution injection mechanism 117 to be moved is arranged.

  In the liquid injector 100 of this embodiment, for example, as shown in FIG. 8, the liquid syringe 200 held by the injection head 110 is connected to the blood vessel V of the human arm A by an extension tube 230 and an injection needle 231. The injection needle 231 is held by an adhesive pad 232 made of a transparent sheet that transmits infrared rays well.

  As shown in FIG. 2, the chemical liquid injection mechanism 117 has an ultrasonic motor 118 as a drive motor, and presses the piston member 220 of the chemical liquid syringe 200 with the power of the ultrasonic motor 118. The chemical solution injection mechanism 117 also includes a load cell 119, and the load cell 119 detects a stress that presses the piston member 220.

  In addition, each part of the injection head 110 of the chemical injection device 100 according to the present embodiment is formed of a nonmagnetic material, and a portion that cannot be formed of a nonmagnetic material is shielded. For example, the ultrasonic motor 118 does not generate a magnetic field even during operation, and non-phosphorus bronze alloy (Cu + Sn + P), titanium alloy (Ti-6Al-4V), magnesium alloy (Mg + Al + Zn), etc. The head body 113 and the like are made of a non-magnetic resin.

  In the chemical injection device 100 of the present embodiment, each part such as the operation panel 103 and the load cell 119 is connected to a computer unit 120. The computer unit 120 includes a CPU (Central Processing Unit) 121, a ROM as shown in FIG. It has hardware such as (Read Only Memory) 122, RAM (Random Access Memory) 123, and I / F (Interface) 124.

  In the chemical injection device 100 according to the present embodiment, the computer unit 120 has a dedicated computer program mounted on an information storage medium such as the ROM 122 as firmware, and each unit to which the CPU 121 is connected corresponding to the computer program. Integrated control.

  Therefore, the computer unit 120 controls the operation of the chemical solution injection mechanism 117 of the injection head 110 corresponding to the manual operation of the operation panel 103, the touch panel 104, and the controller unit 107 of the injection control unit 101, and various kinds of operations corresponding to this operation control and the like. The computer unit 120 causes the touch panel 104 to display and output the data.

  The chemical solution injection device 100 of this embodiment is formed integrally with the dropout detection device, and the injection device main body 101 also serves as the detection device main body. For this reason, the drop-off detection unit 400 is formed separately from the injection apparatus main body 101, and the drop-off detection unit 400 communicates wirelessly with the injection apparatus main body 101. Therefore, the injection control unit 101 of the chemical solution injector 100 also includes a wireless communication unit 126, and this wireless communication unit 126 is also connected to the computer unit 120 as shown in FIG.

  Further, as shown in FIG. 6, the drop-off detection unit 400 has a flat box-shaped unit housing 402, and a laser diode 403 and a phototransistor 404 are disposed downward in the unit housing 402. ing. The laser diode 403 emits an infrared laser beam having a predetermined wavelength downward, and the phototransistor 404 receives the laser beam from below.

  More specifically, the laser beam emitted from the laser diode 403 is set to a wavelength that is satisfactorily transmitted through the human skin, fat, and muscle and is reflected well by the red blood cells. For example, “1.3 (mm) ". An optical filter 406 is disposed at a position facing the laser diode 403 and the phototransistor 404 from below, and the optical filter 406 transmits only infrared light having the above wavelength.

  A circuit board 407 is disposed above the drop-off detection unit 400. The circuit board 407 includes a laser diode 403, a phototransistor 404, a central processing circuit 408, a wireless communication unit 409, as shown in FIG. Are each implemented.

  The central processing circuit 408 is wired to the laser diode 403, the phototransistor 404, and the wireless communication unit 409. The central processing circuit 408 emits a laser beam to the laser diode 403 and detects the laser beam from the output of the phototransistor 404. The central processing circuit 408 includes a logic circuit having a predetermined structure for executing various processing operations, and the wireless communication unit 409 communicates wirelessly with the wireless communication unit 126 of the chemical liquid injector 100.

  The drop detection unit 400 of this embodiment is configured such that the central processing circuit 408 executes various processing operations, whereby a start input unit 411, an end input unit 412, a flow rate detection unit 413, a speed storage unit 414, a drop determination unit 416, an abnormality Various means such as determination means 417 and warning transmission means 418 are logically provided as various functions.

  Further, the chemical injection device 100 also executes various processes corresponding to the computer program in which the computer unit 120 is installed, thereby causing the injection control means 131, the start output means 132, the end output means 133, the warning reception means 134, Various means such as a warning notification unit 136, a reception detection unit 137, and a reception notification unit 138 are logically provided as various functions.

  The injection control means 131 of the chemical solution injection device 100 corresponds to a function of the computer unit 120 controlling the operation of the chemical solution injection mechanism 117 corresponding to the computer program, and will be described in detail later, but corresponds to various input data. Various operations such as start / end / forced stop of the operation of the chemical solution injection mechanism 117 are controlled.

  The start / end output means 132 and 133 correspond to a function of the computer unit 120 causing the wireless communication unit 126 to execute a predetermined operation, and the start output means 132 causes the injection control means 131 to start the operation of the chemical solution injection mechanism 117. The injection start unit 133 outputs data to the dropout detection unit 400 when the injection control unit 131 ends the operation of the chemical solution injection mechanism 117.

  The start / end input means 411 and 412 of the dropout detection unit 400 correspond to the function of the central processing circuit 408 receiving the reception data of the wireless communication unit 409, and the start input means 411 is the start output means 132 of the chemical injection device 100. The start of injection of the chemical liquid is input as data, and the end input means 412 receives the input of the end of injection from the end output means 133 of the chemical liquid injection apparatus 100.

  More specifically, as described above, the injection device main body 101 of the chemical solution injection device 100 and the dropout detection unit 400 perform wireless communication in both directions by the wireless communication units 126 and 409. Predetermined data is wirelessly transmitted to the drop detection unit 400 at the start and end.

  The flow velocity detection means 413 corresponds to a function of the central processing circuit 408 executing predetermined data processing based on the detection result of the photodiode 404, and detects the blood flow velocity from the detection result of the photodiode 404. Various detection methods can be assumed. For example, the laser diode 403 emits a laser beam at a specific frequency, and the frequency of the laser beam reflected by the flowing blood is detected by the photodiode 404, so-called Doppler. It is possible to calculate the blood flow velocity based on the effect.

  Note that the blood flow velocity can be detected from the detection result of the laser beam reflected by the blood in this way, for example, the Internet <URL: “http://www.ntt.co.jp/milab/project/ni_04_1.html > And the like.

  The speed storage means 414 corresponds to a function of the central processing circuit 408 temporarily holding predetermined data in a built-in memory (not shown) corresponding to the data reception of the wireless communication unit 409, and the blood flow before the input of the start of infusion Data is stored as a natural speed.

  The drop-off determination means 416 corresponds to a function in which the central processing circuit 408 executes predetermined data processing based on the data stored in the built-in memory and the detection result of the photodiode 404 in response to data reception of the wireless communication unit 409. If the difference between the blood flow velocity and the natural velocity is less than a predetermined allowable range after the start input and before the end of injection, the drop of the injection needle 231 is determined.

  The abnormality determination means 417 corresponds to a function in which the central processing circuit 408 executes predetermined data processing based on the data stored in the internal memory and the detection result of the photodiode 404, and the detected blood flow velocity falls within a predetermined normal range. When it deviates, the occurrence of abnormality is determined. The warning transmission unit 418 corresponds to a function of the central processing circuit 408 causing the wireless communication unit 409 to perform a predetermined operation, and the determination result of the dropout determination unit 416 and the abnormality determination unit 417 is sent to the chemical injection device 100 as a dropout / abnormality warning. Send data.

  The warning receiving unit 134 of the chemical injection device 100 corresponds to the function of the computer unit 120 receiving the received data of the wireless communication unit 126, and receives the drop / abnormal warning from the warning transmitting unit 418 of the drop detection unit 400. The injection control means 131 described above forcibly stops the chemical solution injection mechanism 117 when the warning receiving means 134 receives the drop / abnormal warning data.

  The warning notification unit 136 corresponds to a function of the computer unit 120 causing the touch panel 104 or the speaker unit 105 to execute a predetermined operation, and the drop / abnormal warning received by the wireless communication unit 126 is displayed on the display output of the touch panel 104 or the speaker unit. The notification is output with the voice output of 105.

  The reception detection unit 137 corresponds to a function of the computer unit 120 detecting the reception state of the wireless communication unit 126 and the like, and detects the reception state of the wireless signal from the drop detection unit 400. The reception notification unit 138 corresponds to a function of the computer unit 120 causing the touch panel 104 or the speaker unit 105 to perform a predetermined operation, and outputs a reception warning when the detected reception state falls below the predetermined state.

  Various means of the chemical liquid injector 100 as described above are realized by using hardware such as the speaker unit 105 if necessary, but the main body functions corresponding to the computer program in which the computer unit 120 is mounted. Is realized.

  Such a computer program, for example, controls various operations such as start / end / forced stop of the operation of the chemical solution injection mechanism 117 in response to various input data, and when the operation of the chemical solution injection mechanism 117 is started. Data is output to the dropout detection unit 400 by wireless transmission of the wireless communication unit 126, and data is output to the dropout detection unit 400 by wireless transmission of the wireless communication unit 126 when the operation of the chemical solution injection mechanism 117 is completed. Receiving a drop / abnormal warning from the drop detection unit 400 by the wireless communication unit 126; forcibly stopping the chemical injection mechanism 117 when the drop / abnormal warning is received; The received drop / abnormal warning is displayed on the touch panel 104 or the speaker unit 1 Notification output with the voice output of 5, detection of the reception state of the wireless signal from the drop detection unit 400 by the wireless communication unit 126, notification output of a reception warning when the detected reception state falls below a predetermined state, It is described to cause the computer unit 120 to execute processing operations such as these.

  Further, the computer program installed in the central processing circuit 408 of the dropout detection unit 400 is, for example, inputting the data of the start and end of injection of the chemical solution from the chemical solution injection device 100 by wireless reception of the wireless communication unit 409, a photodiode Detecting the blood flow velocity from the detection result 404, storing the blood flow velocity before the start of the injection as a natural velocity, storing the blood flow velocity and the natural velocity after the injection start and before the end of the injection. The drop of the injection needle 231 is determined when the difference between the two is reduced from the predetermined allowable range, the occurrence of abnormality is determined when the detected blood flow velocity deviates from the predetermined normal range, and the drop of the injection needle 231 or the occurrence of the abnormality is detected. Processing operation such as sending data to the chemical injection device 100 as a dropout / abnormal warning by the wireless communication unit 409 It is described so as to perform a central processing circuit 408.

[Operation of the embodiment]
In the configuration as described above, when using the drug solution injection device 100 of the present embodiment, for example, an operator connects the injection needle 231 with the extension tube 230 to the drug solution syringe 200 filled with a drug solution such as a contrast medium. As shown in FIG. 7, the injection needle 231 is inserted into the blood vessel V of the arm part A of the subject located in the fluoroscopic imaging unit 301 of the MRI apparatus 300 and held by the adhesive pad 232.

  Next, the drop detection unit 400 is attached to the surface of the adhesive pad 232 with a restraining belt (not shown) or the like, and the chemical syringe 200 is loaded into the injection head 110 of the chemical injection device 100. In such a state, power switches (not shown) for the drop-off detection unit 400 and the injection apparatus main body 101 are respectively turned on, and for example, an operation mode using the drop-off detection unit 400 is set to the injection apparatus main body 101 by a predetermined operation. .

  When the power is turned off, the drop-off detection unit 400 causes the laser diode 403 to emit a laser beam as shown in FIG. 8 (step S1), and this laser beam transmits well through the skin and muscles of the arm portion A. Therefore, the laser beam reflected by the blood is detected by the phototransistor 404 (step S2).

  At this time, if the laser beam is not detected by the phototransistor 404 (step S2), the drop-off detection unit 400 determines that detection is impossible and wirelessly transmits it to the chemical injection device 100 (steps S13 and S14). Then, as shown in FIG. 10, the chemical solution injection device 100 that wirelessly received this inability to detect (Step T <b> 1) gives an abnormal warning such as “Cannot detect blood flow. Check the drop-off detection unit” on the touch panel 104. A notification output is made by the display output and the sound output of the speaker unit 105 (step T17).

  Therefore, for example, when the drop-off detection unit 400 is turned on in a state where it is not attached to the arm part A, the above-described abnormality warning is notified and output from the chemical injection device 100. Therefore, when the worker appropriately attaches the drop detection unit 400 to the arm portion A, the laser beam is detected by the phototransistor 404, so that wireless transmission of an abnormality warning is also stopped.

  In addition, since the chemical injection device 100 that has output the abnormality warning as described above disables the chemical injection mechanism 117 (step T18), the chemical injection device 100 is in a state where the dropout detection unit 400 cannot detect blood flow. No chemical injection is performed. The chemical injection device 100 continues the warning notification until the warning reset is input through the operation panel 103 or the like (steps T17 to T19), and returns to the initial state when the warning reset is input (step T19, T1).

  On the other hand, when the laser beam reflected by the blood is detected by the phototransistor 404 (step S2), the dropout detection unit 400 detects the blood flow velocity from the detection result (step S3), as shown in FIG. Then, it is determined whether the blood flow velocity satisfies a predetermined normal range (step S4).

  If the detected blood flow velocity deviates from the normal range (step S4), the dropout detection unit 400 determines the blood flow abnormality and wirelessly transmits it to the drug solution injector 100 (steps S17 and S18). However, the chemical solution injection device 100 notifies and outputs an abnormal warning such as “the blood flow velocity is abnormal. Please check the patient” by the display output of the touch panel 104 and the voice output of the speaker unit 105. The operation is disabled (steps T17 and T18).

  On the other hand, when the blood flow velocity detected in a state where the start of injection is not wirelessly received satisfies the normal range (steps S7 and S4), the dropout detection unit 400 stores the blood flow velocity as a natural velocity. (Step S5), this storage completion is wirelessly transmitted to the chemical liquid injector 100 (Step S6).

  When the medicinal solution injection device 100 that has received this storage completion data (step T2), when an injection start is input to the operation panel 103 or the like (step T3), the injection start is wirelessly transmitted to the drop detection unit 400 (step T4). The dropout detection unit 400 that wirelessly received the start of injection (step S7) wirelessly returns the start reception to the chemical injection device 100 (step S8).

  Therefore, even if the chemical injection device 100 continuously wirelessly transmits the injection start until a time-out occurs (steps T4 and T16), if the start reception is not wirelessly received (step T5), there is no response from the dropout detection unit. Check the communication status of the drop-off detection unit ”to notify and output an abnormal warning by the display output of the touch panel 104 and the audio output of the speaker unit 105, thereby disabling the chemical injection mechanism 117 (steps T14 and T15). ).

  Also in this case, the warning notification is continued until the warning reset is input on the operation panel 103 or the like (steps T13 to T16), and when the warning reset is input, the injection start is returned to the state of wireless transmission (step T16, T16, T16). T4). Therefore, for example, if the operator improves the communication state with the drop detection unit 400 and inputs a warning reset to the chemical injection device 100, the chemical injection device 100 resumes the wireless transmission of the injection start (step T4). ).

  The chemical injection device 100 that wirelessly received the start reception from the dropout detection unit 400 (step T5) detects the end of injection from the operating range of the chemical injection mechanism 117 (step T10), or an injection stop is input to the operation panel 103 or the like. The injection operation is executed until it is operated (step T9) (step T7).

  At this time, the chemical injection device 100 always detects the communication state with the drop-off detection unit 400, and if the reception state falls below a predetermined state (step T6), “cannot communicate with the drop-off detection unit. Check the communication state. "A reception warning such as" "is output by the display output of the touch panel 104 and the sound output of the speaker unit 105, thereby disabling the chemical injection mechanism 117 (steps T20 and T21).

  In this case, the chemical injection device 100 continues the warning notification and the injection stop until the reception state from the drop-off detection unit 400 becomes good (steps T20 and T21). The injection stop is canceled and the injection operation is restarted (steps T6 and T7). For this reason, the operator only needs to improve the communication state between the drop-off detection unit 400 and the chemical liquid injector 100, and does not need to perform a special input operation.

  Further, the dropout detection unit 400 that has wirelessly returned the start reception to the medicinal solution injection device 100 (step S8) waits for a minute predetermined time when the blood flow velocity changes due to the medicinal solution injection (step S9), and then waits for the laser diode 403. A laser beam is emitted (step S10), and the laser beam reflected by the blood is detected by the phototransistor 404 (step S11).

  At this time, if the laser beam is not detected by the phototransistor 404 (step S11), the dropout detection unit 400 determines that detection is impossible and wirelessly transmits the chemical solution injection apparatus 100 (steps S13 and S14). On the other hand, when the laser beam is detected (step S11), the blood flow velocity is detected from the detection result (step S12). Also in this case, if the blood flow velocity is out of the predetermined normal range (step S13). Then, the blood flow abnormality is determined and wirelessly transmitted to the drug solution injector 100 (steps S17 and S18).

  On the other hand, if the blood flow velocity satisfies the allowable range (step S13), the difference between the blood flow velocity and the natural velocity is detected (step S14), and the difference is a predetermined allowable value as shown in FIG. It is determined whether the range is exceeded (step S19). If the difference is not greater than or equal to the allowable range, the drop detection unit 400 determines that the injection needle 212 has dropped from the blood vessel V (step S21), and wirelessly transmits a drop warning to the drug solution injector 100 (step S22).

  The chemical injection device 100 that wirelessly received the dropout warning from the dropout detection unit 400 (step T8) outputs an abnormal warning such as “The dropout of the injection needle has been detected. Check the injection needle” on the touch panel 104. And a sound output from the speaker unit 105 to make the chemical injection mechanism 117 inoperable (steps T23 and T24).

  For example, when the drug solution is normally injected into the blood vessel V, the blood flow velocity changes due to the injection. Therefore, the dropout detection unit 400 according to the present embodiment stores the blood flow velocity in a state in which no chemical solution is injected as described above as a natural velocity, and stores the blood flow velocity and the natural velocity when the chemical solution is injected. When the difference between the two drops below the allowable range, it is determined that the injection needle 212 has fallen from the blood vessel V. When the determination is made in this manner, the dropout warning is notified and output from the liquid injector 100 as described above, so that the operator checks the injection needle 212 and executes an appropriate treatment.

  Also in this case, the warning notification and the injection stop are continued until the warning reset is input through the operation panel 103 or the like (steps T22 to T24). When the warning reset is input, the injection operation is stopped and the injection ends. Is wirelessly transmitted to the drop detection unit 400 (step T12). The chemical injection device 100 that wirelessly transmits the completion of injection ends all operations, and the dropout detection unit 400 that wirelessly receives the completion of injection also ends all operations (step S23).

  On the other hand, the chemical injection device 100 detects the end of injection from the operating range of the chemical injection mechanism 117 or the like when the chemical injection is executed without any problem (step T7), or stops the injection on the operation panel 103 or the like. Is input (step T9), the injection operation is terminated (step T11). At this time, the chemical solution injector 100 wirelessly transmits the completion of injection to the drop detection unit 400 and ends all operations (step T12). Therefore, the drop detection unit 400 that wirelessly receives the completion of injection also ends all operations. (Step S20).

  In the fluoroscopic imaging system 1000 of this embodiment, since the MRI apparatus 300 is also in wired communication with the chemical solution injection device 100, when the chemical solution injection device 100 temporarily stops the injection operation as described above (steps T14, T15, (T21) The MRI apparatus 300 also temporarily stops the imaging operation, and when the liquid injector 100 finishes the injection operation (steps T11 and T23), the MRI apparatus 300 also ends the imaging operation (not shown).

[Effect of the embodiment]
In the drug solution injection device 100 of the present embodiment, the laser beam is emitted to the blood vessel V in which the injection needle 231 of the arm portion A is inserted as described above, and the laser beam reflected by the blood flowing through the blood vessel V is used. Detect blood flow velocity. Then, the blood flow velocity in the state in which no chemical solution is injected is stored as a natural velocity, and a dropout warning is output when the difference between the blood flow velocity in the state in which the chemical solution is injected and the natural velocity falls below the allowable range. .

  For this reason, when the injection needle 231 drops from the blood vessel V, a drop warning is notified and output, so that the operator can quickly recognize that the injection needle 231 has dropped from the blood vessel V of the subject and take measures. Moreover, in the liquid injector 100 of this embodiment, when the drop of the injection needle 231 is detected as described above, the injection of the liquid is automatically stopped, so that the liquid injection is performed with the injection needle 231 dropped from the blood vessel V. It can be automatically prevented from continuing.

  In addition, since the abnormal warning is output even when the blood flow velocity deviates from the allowable range, the operator can quickly recognize that the blood flow velocity is abnormal and cope with it. Also in this case, since the chemical injection device 100 of this embodiment automatically stops the injection of the chemical solution, it is possible to automatically prevent the injection of the chemical solution from being continued to the subject whose blood flow velocity is abnormal. .

  Furthermore, since the MRI apparatus 300 also stops the imaging operation when the chemical injection apparatus 100 stops the injection operation as described above, it is possible to prevent the MRI apparatus 300 from being inadvertently operated, and the treatment performed by the operator on the subject is the MRI. It is not disturbed by the operation of the device 300. Moreover, since the chemical injection device 100 of this embodiment detects that the injection needle 231 has fallen from the blood vessel V as described above from the change in the blood flow velocity, the drop in accuracy due to the disturbance can be easily detected. Can be implemented in the structure.

  In addition, since the laser diode 403 emits a laser beam having a wavelength that is well transmitted through the skin and muscle of the arm A of the human body and is well reflected by the blood, the blood flow velocity is detected well from the surface of the human body. be able to. In particular, since the optical filter 406 transmits only the laser beam of that wavelength to the phototransistor 404, a malfunction in which the phototransistor 404 detects ambient optical noise can be prevented.

  Furthermore, in the chemical injection device 100 of this embodiment, the dropout detection unit 400 including the laser diode 403, the phototransistor 404, the wireless communication unit 409, and the like, and the injection device main body 101 including the wireless communication unit 126, the touch panel 104, the speaker unit 105, and the like. And are formed separately.

  When the drop detection unit 400 detects the drop of the injection needle 231, the injection apparatus main body 101 outputs a drop warning by wireless communication. Therefore, the drop detection unit 400 that is directly attached to the human body can be reduced in size and weight for easy handling. In addition, the operator who manually moves the injection apparatus main body 101 away from the drop detection unit 400 can be surely recognized the drop warning.

  Moreover, since the injection device main body 101 constantly detects the reception state of the radio signal from the drop-off detection unit 400 and outputs a reception warning when the reception state falls below a predetermined state, the warning signal is wirelessly received due to poor communication. This prevents the dropout warning from being output. In addition, since the injection of the chemical solution is stopped in the state where the dropout warning and the reception warning are both output, it is possible to automatically prevent the injection of the chemical solution while the injection needle 231 is dropped from the blood vessel V. In addition, it is possible to prevent the injection of the chemical solution from being continued in a state where the warning signal cannot be wirelessly received.

[Modification of Embodiment]
The present invention is not limited to the above embodiment, and various modifications are allowed without departing from the scope of the present invention. For example, in the above embodiment, the drop detection device is integrally formed with the chemical injection device 100. However, the drop detection device can be formed separately from the chemical injection device 100.

  However, when the drop of the injection needle 231 is detected as described above, since it is necessary to quickly stop the injection of the chemical solution, it is useful that the drop detection device is integrally formed with the chemical injection device 100. is there. For this reason, when the drop detection device is formed separately from the chemical solution injection device 100, it is preferable that the chemical solution injection device 100 stops the injection operation in conjunction with a warning output of the drop detection device.

  Furthermore, in the above embodiment, it is exemplified that the chemical injection device 100 notifies and outputs a dropout warning and a reception warning. For example, the warning is transmitted to the imaging control unit 302 of the MRI apparatus 300 and output to the liquid crystal display 304 or the like. It is also possible to make it. As described above, since the imaging control unit 302 is installed in a room separate from the fluoroscopic imaging unit 301, it is effective to notify the fluoroscopic imaging unit 301 of a warning.

  In the above embodiment, it is assumed that the chemical injection device 100 is used in the vicinity of the MRI apparatus 300, but this is used in the vicinity of a CT scanner, a PET apparatus, an angio apparatus, an MRA apparatus, an ultrasonic diagnostic apparatus, and the like. Is also possible. Further, in the above embodiment, the drop detection unit 400 and the injection apparatus main body 101 are illustrated as performing wireless communication with radio signals. However, as a communication method thereof, ultrasonic signal wireless communication, optical signal wireless communication, and electrical signal are used. Wired communication, wired communication using optical signals, and the like are also possible.

  In the above embodiment, it is assumed that the adhesive pad 232 that holds the injection needle 231 and attaches the drop-off detection unit 400 to the arm portion A is made of a simple transparent sheet. However, as shown in FIG. The positions of the injection needle 231 and the drop-off detection unit 400 on the adhesive pad 241 may be indicated by print marks 242 and 243.

  In this case, since the relative positions of the injection needle 231 and the drop-off detection unit 400 become appropriate by making the positions of the injection needle 231 and the drop-off detection unit 400 correspond to the positions of the print marks 242 and 243 of the adhesive pad 241, it is easy. In this state, the dropout of the injection needle 231 can be detected well.

  Furthermore, as shown in FIG. 12, the adhesive pad 246 as described above is formed in a bag shape as a protective member, and the drop-off detection unit 400 can be enclosed by the adhesive pad 246. In this case, the drop-off detection unit 400 can be prevented from being soiled by a replaceable adhesive pad as a consumable, so that the drop-off detection unit 400 can be easily sterilized.

  Further, as shown in FIG. 13, the drop detection unit 431 is formed sufficiently small, and a CCD (Charge Coupled Device) camera 432 which is an image pickup means is disposed above the drop detection unit 431 by an arm 433. It is also possible. In this case, since the image around the drop-off detection unit 431 is picked up by the CCD camera 432, for example, the picked-up image is wirelessly transmitted to the chemical injection device 100 and displayed on the touch panel 104 serving as an image display means. .

  For this reason, the operator who operates the chemical injection device 100 can also check an image around the drop-off detection unit 431 on the touch panel 104 when the drop-off warning is displayed on the touch panel 104. It is also possible to display and output such an image only when the drop of the injection needle 231 is detected without always displaying the image.

  Furthermore, in the above embodiment, when the drop of the injection needle 231 is detected, the chemical injection device 100 stops the chemical injection by stopping the chemical injection mechanism 117. For example, the drop of the injection needle 231 is detected. It is also possible that the drop detection device has a unique tube blocking means for blocking the extension tube 230 (not shown).

  Such tube blocking means is formed in, for example, an independent unit structure attached to the extension tube 230, and communicates with the dropout detection unit 400 and the detection apparatus main body wirelessly or by wire. Furthermore, it has a mechanism for opening and closing the extension tube 230 with a drive source such as a solenoid, and when the drop of the injection needle 231 is detected, the extension tube 230 is shut off. In such a dropout detection device, when the dropout of the injection needle 231 is detected, the extension tube 230 is independently blocked. For example, even when the chemical solution injection device 100 is not interlocked with the dropout detection device, the chemical solution injection is automatically stopped. Can be made.

  In the above embodiment, the various units 131 to 131 of the injection apparatus main body 101 are logically realized by functioning corresponding to the computer program in which the computer unit 120 is mounted. It is also possible to form at least a part of the various means 131- by hardware such as a logic circuit.

  On the contrary, in the above-described embodiment, the various means 411 to 411 of the drop-off detection unit 400 are exemplified by predetermined hardware. However, for example, the various means can be realized by a microprocessor that functions in accordance with an installed computer program. It is also possible to logically realize 411 to 411.

  Further, in the above embodiment, it is exemplified that all of the various means 411 to 418 are mounted on the drop detection unit 400, but a part or all of them are mounted on the injection device main body 101 or the detection device main body (not shown). It is also possible. In addition, when the drop detection device is formed separately from the chemical solution injection device 100 as described above, the drop detection unit 400 and the detection device main body can be formed integrally.

  Furthermore, in the above embodiment, one chemical syringe 200 is attached to one recess 112 of the chemical injector 100, but a plurality of chemical syringes 200 can be attached to a plurality of recesses of the injection head. (Not shown).

  Moreover, although the chemical | medical solution syringe 200 was directly mounted | worn with the chemical | medical solution injection apparatus 100 in the said form, since various sizes exist in the chemical | medical solution syringe 200 marketed now, for example, the chemical | medical solution syringe 200 of the largest size is shown. It is also possible that only the chemical solution injection device 100 is directly attached to the chemical solution injection device 100, and various sizes of the chemical solution syringes 200 other than the maximum are attached to the chemical solution injection device 100 via a dedicated cylinder adapter (not shown). .

It is a schematic diagram which shows the logical structure of the drop-off detection unit and chemical | medical solution injection apparatus of embodiment of this invention. It is a block diagram which shows the physical structure of a fluoroscopic imaging system. It is a perspective view which shows the external appearance of a fluoroscopic imaging system. It is a perspective view which shows the external appearance of a chemical injection device. It is a perspective view which shows the state by which a chemical | medical solution syringe is mounted | worn with the injection | pouring head of a chemical | medical solution injection device. It is a vertical front view which shows the internal structure of a drop-off detection unit. It is a perspective view which shows the state which mounts | wears with the drop-off detection unit to the arm part of a human body. It is a flowchart which shows the processing operation of a drop-off detection unit. It is a flowchart which shows the processing operation of a drop-off detection unit. It is a flowchart which shows the main routine of the processing operation of an injection apparatus main body. It is a perspective view which shows the state by which a drop-off detection unit is mounted | worn with an arm part with the adhesive pad of a modification. It is a perspective view which shows the state by which a drop-off detection unit is attached to an arm part by the adhesive pad of another modification. It is a perspective view which shows the other modification of a drop-off detection unit.

Explanation of symbols

DESCRIPTION OF SYMBOLS 100 Chemical solution injection device which is also a drop-off detection device 101 Injection device main body which is also a detection device main body 117 Chemical solution injection mechanism 131 Injection control means 132 Start output means 133 End output means 134 Warning reception means 136 Warning notification means 137 Reception detection means 138 Reception notification means 200 Chemical liquid syringe 230 Extension tube 231 Injection needle 232, 241, 246 Adhesive pad 242, 243 Printing mark 400, 431 Dropping detection unit 403 Laser diode 404 Phototransistor 406 Optical filter 411 Start input means 412 End input means 413 Flow rate detection means 414 Speed Storage unit 416 Dropping determination unit 417 Abnormality determination unit 418 Warning transmission unit

Claims (20)

A dropout detecting device for detecting dropout of an injection needle punctured into a blood vessel in the vicinity of the surface of a human body to inject a chemical solution,
A laser diode for irradiating the blood vessel into which the injection needle is inserted with a laser beam;
A light detecting element for detecting the laser beam reflected by the blood moving through the blood vessel;
A flow velocity detecting means for detecting a blood flow velocity from a detection result of the light detection element;
Start input means for inputting data of the start of injection of the chemical solution;
Speed storage means for storing the blood flow velocity before the input of the start of injection as a natural velocity;
End input means for inputting data of the end of injection of the chemical solution;
A drop determining means for determining drop of the injection needle when the difference between the blood flow velocity and the natural velocity is less than a predetermined allowable range after the injection start input and before the injection end input;
Warning notification means for reporting and outputting a dropout warning when the dropout is determined;
A drop-off detection device. The start input means receives the injection start data from a chemical injection device that injects the chemical liquid filled in a chemical syringe into the blood vessel,
The dropout detection device according to claim 1 , wherein the end input unit receives data of the end of injection from the chemical injection device. It also has an abnormality determination means for determining occurrence of abnormality when the detected blood flow velocity deviates from a predetermined normal range,
The dropout detection device according to any one of claims 1 to 2 , wherein the warning notification means outputs a warning of an abnormality when the occurrence of the abnormality is determined. The dropout detection device according to claim 3 , further comprising a warning transmission unit that transmits data of the abnormality warning to a chemical injection device that injects the chemical solution filled in a chemical syringe into the blood vessel. 5. The dropout detection device according to any one of claims 1 to 4 , further comprising warning transmission means for transmitting the dropout warning data to a chemical injection device that injects the chemical solution filled in a chemical syringe into the blood vessel. . A drop-off detection unit having at least the laser diode and the light detection element;
It has a detection device body that is formed separately from the drop-off detection unit and has at least the warning notification means,
The dropout detection device according to any one of claims 1 to 5 , wherein the dropout detection unit and the detection device main body communicate wirelessly. The dropout detection device according to claim 6 , wherein the detection device main body is integrally incorporated in a chemical liquid injector that injects the chemical liquid filled in a chemical syringe into the blood vessel. The detection device body is
Reception detecting means for detecting a reception state of the radio signal;
A reception notification means for reporting and outputting a reception warning when the detected reception state falls below a predetermined state;
The drop-off detection device according to claim 6 or 7 . Image capturing means for capturing an image of a position of the human body where the injection needle is inserted;
The dropout detection device according to any one of claims 1 to 8 , further comprising image display means for displaying and outputting the captured image. The drop detection unit also has an image capturing means for capturing an image of a position of the human body where the injection needle is inserted,
The dropout detection device according to any one of claims 6 to 8 , further comprising image display means for displaying and outputting the image picked up by the detection device body. A dropout detection unit having at least the laser diode and the light detection element;
A transparent adhesive pad on which the position of the injection needle is written and the drop detection unit is detachably attached to the human body surface;
The dropout detection device according to any one of claims 1 to 10 , further comprising: The adhesive pad is formed separately from the drop-off detection unit and can be exchanged,
The dropout detection device according to claim 11 , wherein a position of the dropout detection unit is also written on the adhesive pad. The drop-off detection device according to claim 11 or 12 , wherein a protective member that transmits the laser beam and encloses the drop-off detection unit in a replaceable manner is formed integrally with the adhesive pad. A dropout detection unit having at least the laser diode and the light detection element;
An exchangeable protection member that encloses the drop-off detection unit and transmits the laser beam;
The dropout detection device according to any one of claims 1 to 12 , further comprising: An extension tube for flowing the chemical solution is connected to the injection needle,
The dropout detection device according to any one of claims 1 to 14 , further comprising tube blocking means for blocking the extension tube when the dropout is determined. A chemical solution injection device for injecting a chemical solution filled in a chemical solution syringe into a blood vessel near the surface of the human body with an extension tube and an injection needle,
A chemical injection mechanism for driving the chemical syringe;
Injection control means for controlling the operation of the chemical injection mechanism;
Start output means for outputting data to the dropout detection device according to claim 1 when the injection control means starts operation of the chemical solution injection mechanism;
An end output means for outputting data of the end of injection to the drop-off detection device when the injection control means ends the operation of the chemical solution injection mechanism;
A chemical injection device. A chemical solution injection device for injecting a chemical solution filled in a chemical solution syringe into a blood vessel near the surface of the human body with an extension tube and an injection needle,
A chemical injection mechanism for driving the chemical syringe;
Warning receiving means for receiving data of the abnormality warning from the dropout detection device according to claim 4 ;
Injection control means for forcibly stopping the chemical injection mechanism when the abnormality warning is received;
A chemical injection device. The chemical injection device according to claim 17 , further comprising warning notifying means for notifying and outputting the abnormality warning that has been received. A chemical solution injection device for injecting a chemical solution filled in a chemical solution syringe into a blood vessel near the surface of the human body with an extension tube and an injection needle,
A chemical injection mechanism for driving the chemical syringe;
Warning receiving means for receiving data of the dropout warning from the dropout detection device according to claim 5 ;
Injection control means for forcibly stopping the chemical injection mechanism when the drop warning is received;
A chemical injection device. The chemical injection device according to claim 19 , further comprising warning notifying means for notifying and outputting the drop-off warning that has been received.

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