JP4344241B2 - トリアジン誘導体、およびサンスクリーンとしてのその使用 - Google Patents
トリアジン誘導体、およびサンスクリーンとしてのその使用 Download PDFInfo
- Publication number
- JP4344241B2 JP4344241B2 JP2003521215A JP2003521215A JP4344241B2 JP 4344241 B2 JP4344241 B2 JP 4344241B2 JP 2003521215 A JP2003521215 A JP 2003521215A JP 2003521215 A JP2003521215 A JP 2003521215A JP 4344241 B2 JP4344241 B2 JP 4344241B2
- Authority
- JP
- Japan
- Prior art keywords
- sub
- alkyl
- acid
- unsubstituted
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 CC(*)(*)C(C(*)(*)C(C(*)=O)=C(*)NCc1nc(*)nc(NC(*)=C(C(C)(*)C(C(*)(*)*)=O)C(*)=O)n1)=O Chemical compound CC(*)(*)C(C(*)(*)C(C(*)=O)=C(*)NCc1nc(*)nc(NC(*)=C(C(C)(*)C(C(*)(*)*)=O)C(*)=O)n1)=O 0.000 description 2
- FQUNFJULCYSSOP-UHFFFAOYSA-N CC(C)(C)CC(C)(C)c(cc1-[n]2nc(cccc3)c3n2)cc(Cc(cc(C(C)(C)CC(C)(C)C)cc2-[n]3nc(cccc4)c4n3)c2O)c1O Chemical compound CC(C)(C)CC(C)(C)c(cc1-[n]2nc(cccc3)c3n2)cc(Cc(cc(C(C)(C)CC(C)(C)C)cc2-[n]3nc(cccc4)c4n3)c2O)c1O FQUNFJULCYSSOP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4966—Triazines or their condensed derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/14—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom
- C07D251/16—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to only one ring carbon atom
- C07D251/18—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to only one ring carbon atom with nitrogen atoms directly attached to the two other ring carbon atoms, e.g. guanamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/54—Three nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/54—Three nitrogen atoms
- C07D251/70—Other substituted melamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Cosmetics (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01810796 | 2001-08-17 | ||
| CH16992001 | 2001-09-14 | ||
| PCT/EP2002/008888 WO2003016289A1 (en) | 2001-08-17 | 2002-08-08 | Triazine derivatives and their use as sunscreens |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005501855A JP2005501855A (ja) | 2005-01-20 |
| JP2005501855A5 JP2005501855A5 (https=) | 2006-01-05 |
| JP4344241B2 true JP4344241B2 (ja) | 2009-10-14 |
Family
ID=25739004
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003521215A Expired - Fee Related JP4344241B2 (ja) | 2001-08-17 | 2002-08-08 | トリアジン誘導体、およびサンスクリーンとしてのその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7038046B2 (https=) |
| EP (1) | EP1423371B1 (https=) |
| JP (1) | JP4344241B2 (https=) |
| AT (1) | ATE485281T1 (https=) |
| DE (1) | DE60238066D1 (https=) |
| DK (1) | DK1423371T3 (https=) |
| WO (1) | WO2003016289A1 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7574545B2 (en) * | 2000-10-16 | 2009-08-11 | Electronics For Imaging, Inc. | Method and apparatus for controlling a document output device with a control request stored at a server |
| US6748471B1 (en) * | 2000-10-16 | 2004-06-08 | Electronics For Imaging, Inc. | Methods and apparatus for requesting and receiving a print job via a printer polling device associated with a printer |
| FR2867188A1 (fr) * | 2004-03-03 | 2005-09-09 | Oreal | Derives de s-triazine possedant un groupement para-alcoxyphenyle et au moins un groupement aminobenzalmaloniques greffes ; compositions cosmetiques contenant ces derives; utilisations desdits derives de s-tri |
| US20070286827A1 (en) * | 2006-06-12 | 2007-12-13 | Esschem, Inc. | Optical brighter and uv stabilizer for acrylic enhancements |
| WO2008003064A2 (en) * | 2006-06-29 | 2008-01-03 | Martek Biosciences Corporation | Sweetened oil compositions and methods of making |
| WO2008022946A1 (en) * | 2006-08-24 | 2008-02-28 | Unilever Plc | Photostable cosmetic compositions |
| US20080096782A1 (en) * | 2006-10-19 | 2008-04-24 | L'oreal | Aqueous systems containing phospholipid, surfactant and phosphate ester for water-insoluble materials |
| US20080097070A1 (en) * | 2006-10-19 | 2008-04-24 | L'oreal | Aqueous polyamine-containing systems for water-insoluble materials |
| AU2010223919B2 (en) | 2009-03-13 | 2016-03-31 | Les Laboratoires Servier | Methods and compositions for cell-proliferation-related disorders |
| RU2561132C2 (ru) | 2009-06-29 | 2015-08-20 | Аджиос Фармасьютикалз, Инк. | Производные хинолинсульфонамидов и их применение для модулирования пкм2 активности |
| EP3561077B1 (en) | 2009-10-21 | 2022-12-21 | Les Laboratoires Servier | Methods for cell-proliferation-related disorders |
| CA2797158A1 (en) | 2010-05-10 | 2011-11-17 | Segetis, Inc. | Alkyl ketal esters as dispersants and slip agents for particulate solids, methods of manufacture, and uses thereof |
| TWI519569B (zh) * | 2010-12-28 | 2016-02-01 | Nissan Chemical Ind Ltd | A coating solution for forming a polyimide film, a liquid crystal aligning agent, a polyimide film, a liquid crystal alignment film, and a liquid crystal display element |
| WO2012092546A2 (en) * | 2010-12-30 | 2012-07-05 | L'oreal S.A. | Mascara compositions containing an oil-dispersible micronized wax and a water-dispersible wax |
| SG194697A1 (en) | 2011-05-03 | 2013-12-30 | Agios Pharmaceuticals Inc | Pyruvate kinase activators for use in therapy |
| CN102827073A (zh) | 2011-06-17 | 2012-12-19 | 安吉奥斯医药品有限公司 | 治疗活性组合物和它们的使用方法 |
| CN102827170A (zh) | 2011-06-17 | 2012-12-19 | 安吉奥斯医药品有限公司 | 治疗活性组合物和它们的使用方法 |
| NZ627096A (en) | 2012-01-06 | 2017-02-24 | Agios Pharmaceuticals Inc | Triazinyl compounds and their methods of use |
| US9474779B2 (en) | 2012-01-19 | 2016-10-25 | Agios Pharmaceuticals, Inc. | Therapeutically active compositions and their methods of use |
| WO2014062511A1 (en) | 2012-10-15 | 2014-04-24 | Agios Pharmaceuticals, Inc. | Therapeutic compounds and compositions |
| WO2015003355A2 (en) | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| MY185687A (en) | 2013-07-11 | 2021-05-30 | Agios Pharmaceuticals Inc | N,6-bis(aryl or heteroaryl)-1,3,5-triazine-2,4-diamine compounds as idh2 mutants inhibitors for the treatment of cancer |
| CN105593215B (zh) | 2013-07-11 | 2019-01-15 | 安吉奥斯医药品有限公司 | 用于治疗癌症的作为idh2突变体抑制剂的2,4-或4,6-二氨基嘧啶化合物 |
| WO2015003360A2 (en) * | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| US9579324B2 (en) | 2013-07-11 | 2017-02-28 | Agios Pharmaceuticals, Inc | Therapeutically active compounds and their methods of use |
| US20150031627A1 (en) | 2013-07-25 | 2015-01-29 | Agios Pharmaceuticals, Inc | Therapeutically active compounds and their methods of use |
| KR20240010105A (ko) | 2014-03-14 | 2024-01-23 | 아지오스 파마슈티컬스 아이엔씨. | 치료적으로 활성인 화합물의 약제학적 조성물 |
| FI3307271T3 (fi) | 2015-06-11 | 2023-10-17 | Agios Pharmaceuticals Inc | Pyruvaattikinaasin aktivaattorien käyttämisen menetelmä |
| SG11201803088PA (en) | 2015-10-15 | 2018-05-30 | Agios Pharmaceuticals Inc | Combination therapy for treating malignancies |
| PT3362066T (pt) | 2015-10-15 | 2021-11-16 | Celgene Corp | Terapia de combinação para tratar malignidades |
| CN107827764A (zh) * | 2017-11-27 | 2018-03-23 | 上海应用技术大学 | 一种双β‑氨基酮或双β‑氨基酯类的制备方法 |
| US10980788B2 (en) | 2018-06-08 | 2021-04-20 | Agios Pharmaceuticals, Inc. | Therapy for treating malignancies |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4105923A1 (de) * | 1991-02-26 | 1992-08-27 | Basf Ag | P-aminozimtsaeure-substituierte triazine |
| DE4223890A1 (de) * | 1992-02-19 | 1993-08-26 | Merck Patent Gmbh | Triazin-derivate |
| FR2744721B1 (fr) * | 1996-02-12 | 1999-06-18 | Oreal | Nouveaux derives insolubles de s-triazine, leur procede de preparation, compositions les contenant et leurs utilisations |
-
2002
- 2002-08-08 DE DE60238066T patent/DE60238066D1/de not_active Expired - Lifetime
- 2002-08-08 JP JP2003521215A patent/JP4344241B2/ja not_active Expired - Fee Related
- 2002-08-08 DK DK02772133.1T patent/DK1423371T3/da active
- 2002-08-08 EP EP02772133A patent/EP1423371B1/en not_active Expired - Lifetime
- 2002-08-08 WO PCT/EP2002/008888 patent/WO2003016289A1/en not_active Ceased
- 2002-08-08 AT AT02772133T patent/ATE485281T1/de not_active IP Right Cessation
- 2002-08-08 US US10/486,761 patent/US7038046B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE485281T1 (de) | 2010-11-15 |
| DK1423371T3 (da) | 2011-02-07 |
| WO2003016289A1 (en) | 2003-02-27 |
| DE60238066D1 (de) | 2010-12-02 |
| EP1423371B1 (en) | 2010-10-20 |
| JP2005501855A (ja) | 2005-01-20 |
| EP1423371A1 (en) | 2004-06-02 |
| US20040242579A1 (en) | 2004-12-02 |
| US7038046B2 (en) | 2006-05-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
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| A977 | Report on retrieval |
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| A521 | Request for written amendment filed |
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| A521 | Request for written amendment filed |
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| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
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| A01 | Written decision to grant a patent or to grant a registration (utility model) |
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| A61 | First payment of annual fees (during grant procedure) |
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| FPAY | Renewal fee payment (event date is renewal date of database) |
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| R150 | Certificate of patent or registration of utility model |
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| LAPS | Cancellation because of no payment of annual fees |