JP4327818B2 - 微粉砕ビニルラクタムポリマーを基材とする、高強度錠剤用結合剤、ならびにその製造および使用 - Google Patents

微粉砕ビニルラクタムポリマーを基材とする、高強度錠剤用結合剤、ならびにその製造および使用 Download PDF

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Publication number
JP4327818B2
JP4327818B2 JP2006114546A JP2006114546A JP4327818B2 JP 4327818 B2 JP4327818 B2 JP 4327818B2 JP 2006114546 A JP2006114546 A JP 2006114546A JP 2006114546 A JP2006114546 A JP 2006114546A JP 4327818 B2 JP4327818 B2 JP 4327818B2
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Japan
Prior art keywords
binder
weight
less
tablet
spraying
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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JP2006114546A
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English (en)
Japanese (ja)
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JP2006316266A5 (https=
JP2006316266A (ja
Inventor
コルター，カール
アシャール，ヘルマン
フスネッガー，ベルンハルト
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BASF SE
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BASF SE
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/06—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
    • C08F226/10—N-Vinyl-pyrrolidone
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/06—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Cephalosporin Compounds (AREA)
JP2006114546A 2005-04-20 2006-04-18 微粉砕ビニルラクタムポリマーを基材とする、高強度錠剤用結合剤、ならびにその製造および使用 Expired - Lifetime JP4327818B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005018465A DE102005018465A1 (de) 2005-04-20 2005-04-20 Bindemittel für Tabletten mit hoher Festigkeit auf Basis von Herstellung und Verwendung von feinteiligen Vinyllactampolymerenn, deren Herstellung und Verwendung

Publications (3)

Publication Number Publication Date
JP2006316266A JP2006316266A (ja) 2006-11-24
JP2006316266A5 JP2006316266A5 (https=) 2009-05-21
JP4327818B2 true JP4327818B2 (ja) 2009-09-09

Family

ID=36930321

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006114546A Expired - Lifetime JP4327818B2 (ja) 2005-04-20 2006-04-18 微粉砕ビニルラクタムポリマーを基材とする、高強度錠剤用結合剤、ならびにその製造および使用

Country Status (7)

Country Link
US (1) US8268350B2 (https=)
EP (1) EP1714988B1 (https=)
JP (1) JP4327818B2 (https=)
CN (1) CN1854232B (https=)
AT (1) ATE383381T1 (https=)
DE (2) DE102005018465A1 (https=)
ES (1) ES2299142T3 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005049001A1 (de) * 2005-10-11 2007-04-12 Basf Ag Verfahren zur Herstellung von direkttablettierbaren Ibuprofen-Formulierungen
EP2046854B1 (de) * 2006-07-21 2019-12-04 Basf Se Polyurethanschaumstoffe mit desinfizierender und/oder bleichender wirkung

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5176713A (en) * 1987-07-15 1993-01-05 Colgate-Palmolive Co. Stable non-aqueous cleaning composition method of use
US4986048A (en) 1990-01-11 1991-01-22 Pittsburgh Corning Corporation Method and apparatus for erecting a glass block wall
US4968562A (en) * 1990-02-27 1990-11-06 Minnesota Mining And Manufacturing Company Hollow acid-free acrylate polymeric microspheres having multiple small voids
DE4139963A1 (de) 1991-12-04 1993-06-09 Basf Ag, 6700 Ludwigshafen, De Redispergierbares dispersionspulver aus n-vinylpyrrolidon-vinylacetat-copolymerisat, dessen herstellung und verwendung
US5252704A (en) * 1992-06-05 1993-10-12 Air Products And Chemicals, Inc. Redispersible polymer powders using polyvinyl pyrrolidone as a dispersing aid
DE4421178A1 (de) 1994-06-17 1995-12-21 Basf Ag Verfahren zur Herstellung von Polymerisaten auf Basis von 1-Vinylimidazolen
DE4442900A1 (de) 1994-12-02 1996-06-05 Basf Ag Verfahren zur Herstellung von pulverförmigen Wasserstoffperoxid-Polymer-Komplexen
DE4443358A1 (de) * 1994-12-06 1996-06-13 Basf Ag Depot-Arzneimittel
US8236352B2 (en) * 1998-10-01 2012-08-07 Alkermes Pharma Ireland Limited Glipizide compositions
US6969529B2 (en) * 2000-09-21 2005-11-29 Elan Pharma International Ltd. Nanoparticulate compositions comprising copolymers of vinyl pyrrolidone and vinyl acetate as surface stabilizers
DE19915420A1 (de) * 1999-04-06 2000-10-12 Basf Ag Stabilisierte Polyvinylpyrrolidon-Zubereitungen
JP3900428B2 (ja) * 2003-01-08 2007-04-04 第一工業製薬株式会社 粉末状ビニルピロリドン重合体の製造方法
CN1226320C (zh) * 2003-06-30 2005-11-09 厦门大学 N－乙烯基吡咯烷酮和乙酸乙烯酯共聚物的制备方法

Also Published As

Publication number Publication date
ATE383381T1 (de) 2008-01-15
ES2299142T3 (es) 2008-05-16
EP1714988B1 (de) 2008-01-09
CN1854232B (zh) 2010-10-13
DE102005018465A1 (de) 2006-11-02
DE502006000273D1 (de) 2008-02-21
EP1714988A1 (de) 2006-10-25
US20060240102A1 (en) 2006-10-26
CN1854232A (zh) 2006-11-01
US8268350B2 (en) 2012-09-18
JP2006316266A (ja) 2006-11-24

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