JP4308231B2 - 測光による面内検出 - Google Patents
測光による面内検出 Download PDFInfo
- Publication number
- JP4308231B2 JP4308231B2 JP2006215494A JP2006215494A JP4308231B2 JP 4308231 B2 JP4308231 B2 JP 4308231B2 JP 2006215494 A JP2006215494 A JP 2006215494A JP 2006215494 A JP2006215494 A JP 2006215494A JP 4308231 B2 JP4308231 B2 JP 4308231B2
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- container
- disc
- light beam
- optical means
- disk
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/0303—Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0654—Lenses; Optical fibres
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0803—Disc shape
- B01L2300/0806—Standardised forms, e.g. compact disc [CD] format
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
- B01L2300/168—Specific optical properties, e.g. reflective coatings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N35/00069—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk
Description
3 回転軸
7 容器
9 光学手段
10 反射面
11 光学手段
14 入射面
18、18’ マイクロチャンネル
21 光線
31 反射面
51 光学手段(反射面)
53 光学手段
Claims (7)
- 化学サンプル及び/又は流体サンプルの光検出のためのディスク状分析装置であって、流体サンプル用の複数の容器(7)及び該容器を通して光線を導くための光学手段(9、51)を有する回転可能なディスク状本体(1)を備え、少なくとも幾つかの容器(7)に対して、少なくとも2つのマイクロチャンネル(18、18')が配置され、第1のマイクロチャンネル(18')は分析対象の液体を容器内へ注入するために、第2のマイクロチャンネル(18)は容器(7)内に蓄積された気泡を除去するために設けられており、該光学手段(9、51)の少なくとも一部が、最初に、光線の少なくとも一部がディスク状本体(1)上の半径方向外向きの方向に対してある角度に偏向され且つ該容器を通して導かれ、次に、容器通過後にディスク状装置の面から外へ偏向されるように設計され及び/又は配置されていることを特徴とする、前記分析装置。
- 光学手段が少なくとも2つの反射面を備え、1つの面は容器の前に、別の面は容器の後に備えられている、請求項1に記載の装置。
- ディスクの面に垂直に到達する光線(21)が、ディスク状本体(1)上/又はディスク状本体(1)内に配置された各容器に向けてディスク状装置(1)の面の中へと偏向されるように、光学手段の反射面(10)がディスク状装置(1)の面に対して45°の角度に配置されていることを特徴とする、請求項1又は2に記載の装置。
- 前記光学手段が、反射面が回転可能なディスク状装置(1)の円上に配置されるよう環状の形を有する反射面(51)を備えていることを特徴とする、請求項1に記載の装置。
- 流体サンプル用の複数の容器を有する回転可能なディスク状本体上に配置された化学サンプル及び/又は流体サンプルの光検出のための分析方法であって、光線、又は少なくともその一部が、最初に、ディスク状本体上に配置された光学手段によって、回転可能なディスク状本体の半径方向に外向きの方向、すなわち半径方向外向きに方向付けられた回転力の方向に対して各々ある角度を成す方向に容器を通して導かれ、容器通過後の光線はディスク状本体の面の外へと偏向され、容器を通して導かれた光線の部分的な吸収が分析目的に用いられ、少なくとも幾つかの容器に対して、少なくとも2つのマイクロチャンネルが配置され、第1のマイクロチャンネルは分析対象の液体を容器内へ注入するために、第2のマイクロチャンネルは容器内に蓄積された気泡を除去するために設けられていることを特徴とする、前記方法。
- 第1のステップにおいては、容器内の第1ボリュームが、容器を通して導かれた光線によって検出され、この光線が分析の目的で測光法で検出され;
第2のステップにおいては、容器の中へ付加的なボリュームが加えられ、混合後、第2の光学分析ステップが行われる、
ことを特徴とする、請求項5に記載の方法。 - 光学手段を配置することを目的として、光線がディスク状本体上の半径方向外向きの方向に対してある角度に配置されるために該光学手段の少なくとも一部の面が反射面を創出するよう設けられ、及び/又は該反射面の少なくとも一部の面が環状であり、且つ射出成形によって製造される該ディスク状本体の円上に配置されるように、ポリマー融液の注入前に各インサートが型内に配置されることを特徴とする、ポリマー融液の型内への注入による請求項1〜4のいずれか1項に記載の分析装置の製造方法。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05017277A EP1752758A1 (en) | 2005-08-09 | 2005-08-09 | Photometric in plane detection using a rotatable disc |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2007052010A JP2007052010A (ja) | 2007-03-01 |
JP4308231B2 true JP4308231B2 (ja) | 2009-08-05 |
Family
ID=35447927
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006215494A Active JP4308231B2 (ja) | 2005-08-09 | 2006-08-08 | 測光による面内検出 |
Country Status (5)
Country | Link |
---|---|
US (1) | US7586612B2 (ja) |
EP (2) | EP1752758A1 (ja) |
JP (1) | JP4308231B2 (ja) |
AT (1) | ATE556311T1 (ja) |
CA (1) | CA2555519C (ja) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102005062174C5 (de) * | 2005-12-23 | 2010-05-06 | INSTITUT FüR MIKROTECHNIK MAINZ GMBH | Meßchip |
GB0905325D0 (en) * | 2009-03-30 | 2009-05-13 | Selex Sensors & Airborne Sys | Detection system |
DE102010013752A1 (de) * | 2010-03-31 | 2011-10-06 | Roche Diagnostics Gmbh | Multifunktionelle Detektionsküvette |
KR101881451B1 (ko) | 2011-06-29 | 2018-07-25 | 삼성전자주식회사 | 유체내 기체 제거를 위한 미세유체 채널 |
WO2013079619A1 (en) * | 2011-12-01 | 2013-06-06 | Biosurfit, S.A. | Photometric device and method |
US10788416B2 (en) * | 2013-10-03 | 2020-09-29 | Rosemount Inc. | Multiple wavelength light source for colorimetric measurement |
US9618393B2 (en) * | 2014-09-24 | 2017-04-11 | Freestone Environmental Services, Inc. | Apparatus for measuring hexavalent chromium in water |
EP3312586B1 (en) * | 2015-06-16 | 2020-12-16 | Tascom Co., Ltd. | Biological material measuring instrument |
US9909975B1 (en) | 2016-10-07 | 2018-03-06 | Biosurfit, S.A. | Device for rotation about an axis of rotation to drive liquid flow within the device comprising a first element, a second element and the radially outer wall of a cavity define a detection chamber |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3504981A (en) * | 1965-08-09 | 1970-04-07 | Harry H Malvin | Dual colorimeter system for sequential analysis of a plurality of samples |
US3748044A (en) * | 1969-09-02 | 1973-07-24 | Abbott Lab | Digital chemical analysis apparatus |
FR2409514A1 (fr) * | 1977-11-17 | 1979-06-15 | Bretaudiere Jean Pierre | Perfectionnement aux appareils d'analyse par centrifugation |
JPS55136958A (en) * | 1979-04-14 | 1980-10-25 | Olympus Optical Co Ltd | Automatic analyzer |
US4325910A (en) * | 1979-07-11 | 1982-04-20 | Technicraft, Inc. | Automated multiple-purpose chemical-analysis apparatus |
JPS587545A (ja) * | 1981-07-08 | 1983-01-17 | Olympus Optical Co Ltd | 分析装置 |
US5122284A (en) * | 1990-06-04 | 1992-06-16 | Abaxis, Inc. | Apparatus and method for optically analyzing biological fluids |
US5478750A (en) * | 1993-03-31 | 1995-12-26 | Abaxis, Inc. | Methods for photometric analysis |
GB9418981D0 (en) * | 1994-09-21 | 1994-11-09 | Univ Glasgow | Apparatus and method for carrying out analysis of samples |
US20020076354A1 (en) * | 2000-12-01 | 2002-06-20 | Cohen David Samuel | Apparatus and methods for separating components of particulate suspension |
JP4423189B2 (ja) * | 2002-05-31 | 2010-03-03 | ユィロス・パテント・アクチボラグ | 表面プラズモン共鳴に基づく検出装置 |
-
2005
- 2005-08-09 EP EP05017277A patent/EP1752758A1/en not_active Withdrawn
-
2006
- 2006-07-07 EP EP06014095A patent/EP1752759B1/en active Active
- 2006-07-07 AT AT06014095T patent/ATE556311T1/de active
- 2006-08-08 JP JP2006215494A patent/JP4308231B2/ja active Active
- 2006-08-08 US US11/463,110 patent/US7586612B2/en active Active
- 2006-08-08 CA CA2555519A patent/CA2555519C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1752759A1 (en) | 2007-02-14 |
CA2555519A1 (en) | 2007-02-09 |
US7586612B2 (en) | 2009-09-08 |
CA2555519C (en) | 2010-02-16 |
US20070165229A1 (en) | 2007-07-19 |
JP2007052010A (ja) | 2007-03-01 |
EP1752758A1 (en) | 2007-02-14 |
ATE556311T1 (de) | 2012-05-15 |
EP1752759B1 (en) | 2012-05-02 |
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