JP4307550B2 - 単量体状タンパク質の送達のための方法及び組成物 - Google Patents

単量体状タンパク質の送達のための方法及び組成物 Download PDF

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Publication number
JP4307550B2
JP4307550B2 JP51899697A JP51899697A JP4307550B2 JP 4307550 B2 JP4307550 B2 JP 4307550B2 JP 51899697 A JP51899697 A JP 51899697A JP 51899697 A JP51899697 A JP 51899697A JP 4307550 B2 JP4307550 B2 JP 4307550B2
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Prior art keywords
insulin
multimeric
monomeric
carrier surface
flow path
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Expired - Fee Related
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Japanese (ja)
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JP2000502993A5 (https=
JP2000502993A (ja
Inventor
アントウェルプ，ウィリアム ピー． バン
アントウェルプ，ナネッティ バン
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メドトロニック ミニメッド、 インコーポレイティド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • External Artificial Organs (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP51899697A 1995-11-13 1996-11-12 単量体状タンパク質の送達のための方法及び組成物 Expired - Fee Related JP4307550B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US661195P 1995-11-13 1995-11-13
US60/006,611 1995-11-13
PCT/US1996/018115 WO1997017945A2 (en) 1995-11-13 1996-11-12 Methods and compositions for the delivery of monomeric proteins

Publications (3)

Publication Number Publication Date
JP2000502993A JP2000502993A (ja) 2000-03-14
JP2000502993A5 JP2000502993A5 (https=) 2004-10-14
JP4307550B2 true JP4307550B2 (ja) 2009-08-05

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Application Number Title Priority Date Filing Date
JP51899697A Expired - Fee Related JP4307550B2 (ja) 1995-11-13 1996-11-12 単量体状タンパク質の送達のための方法及び組成物

Country Status (8)

Country Link
US (1) US5807315A (https=)
EP (1) EP0861089B1 (https=)
JP (1) JP4307550B2 (https=)
AU (1) AU7678196A (https=)
CA (1) CA2236579C (https=)
DE (1) DE69622421T2 (https=)
DK (1) DK0861089T3 (https=)
WO (1) WO1997017945A2 (https=)

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Also Published As

Publication number Publication date
DE69622421D1 (de) 2002-08-22
DK0861089T3 (da) 2002-10-07
DE69622421T2 (de) 2003-03-20
EP0861089B1 (en) 2002-07-17
WO1997017945A3 (en) 1997-07-10
CA2236579A1 (en) 1997-05-22
WO1997017945A2 (en) 1997-05-22
CA2236579C (en) 2009-06-30
JP2000502993A (ja) 2000-03-14
EP0861089A2 (en) 1998-09-02
US5807315A (en) 1998-09-15
AU7678196A (en) 1997-06-05

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