JP4212561B2 - Antibacterial paper, non-woven or textile products - Google Patents

Description

  The present invention relates to a paper, a nonwoven fabric or a textile product which contains α, α-trehalose and polyphenol and has a continuous antioxidant / antibacterial and deodorizing action.

Conventional methods have been provided for impregnating plant-derived extracts with antibacterial and deodorant effects into paper, non-woven fabrics, textile products, etc., and treating catechins extracted from tea leaves into paper products, synthetic resin products or wood products And a method for imparting a sterilizing and deodorizing function has been filed. (Japanese Patent Laid-Open No. 2001-294018)
However, in these methods, the stability over time is generally poor, and air oxidation and auto-oxidation change the quality, the product is easily deteriorated, and the antibacterial action is not sufficient.

  On the other hand, a freshness-keeping agent and a freshness-keeping method using polyphenol and α, α-trehalose are known (Japanese Patent Laid-Open No. 2003-225047).

  According to the freshness-keeping agent and the freshness-keeping method in the above publication, fish such as fresh fish is immersed in an aqueous solution of porphenol and α, α-trehalose. In the case of this method, since the fish body is immersed as it is, it is difficult to understand the difference in appearance, and it can not be left immersed for a long time due to bacterial growth, risk of deterioration of the fish body, etc. Has not reached.

  In general, during the period from when fresh fish is caught to the end user, an expert method selects, manages, and operates optimal methods such as refrigeration, freezing, and ice storage according to the fish type and product purpose.

  However, in sashimi, izakayas, hotels, restaurants, etc., where fresh fish is purchased, cooked and sold, be sure to thaw the fish as a pre-preparation before opening or store it in a refrigerator. However, there was no effective storage method, and items that were not sold on the day could not be provided as sashimi the next day because the surface turned black even when stored in the refrigerator.

  In order to solve the above-mentioned problem, a method has been filed in which a catechin is added to an antioxidant / antibacterial agent and a shell powder is added to a pulp sheet as an antibacterial agent (Japanese Patent Laid-Open No. 2002-345397).

However, in this method, catechin cannot be added in a large amount due to the strong scent of catechin, the antioxidant activity of catechin, the stability over time of antibacterial activity, and the part of fish that is in contact with moisture via moisture There was a drawback that the antioxidant activity did not last for a long time.
JP 2001-294018 A JP 2003-225047 A JP 2002-345397 A

  The present invention prevents air oxidation and auto-oxidation of paper, non-woven fabric and textile products using plant-derived extracts having antibacterial and deodorizing effects, improves stability over time and prevents product deterioration, safety Using strong plant-derived extracts to maintain strong antibacterial activity on paper, non-woven fabrics and textile products, and to provide continuous antioxidant action on paper, non-woven fabrics and textile products to prevent oxidation of the objects in contact with them Is an issue. That is, an object of the present invention is to provide an antibacterial agent exhibiting a stable antibacterial action and a deodorizing action, and a paper, a nonwoven fabric or a textile product imparted with an antibacterial and deodorant action.

  In order to solve the above-mentioned problems, the present inventors are α, which is harmless in food hygiene and has antibacterial and antioxidant effects on polyphenols and lipids, suppresses fish odor production, and stabilizes SOD-like activity. Focusing on the use of α-trehalose, we have continued intensive studies. As a result, α, α-trehalose and polyphenol are contained in paper, non-woven fabric, and fiber product, or paper, non-woven fabric, and fiber product are impregnated in an aqueous solution of α, α-trehalose and polyphenol, and dried. It came to be completed.

  That is, this invention is a paper, a nonwoven fabric, and a textile product characterized by containing a polyphenol and (alpha), (alpha) -trehalose. Further, the paper, nonwoven fabric or textile product of the present invention can contain any of salt, salt contained in seawater, or seawater containing these salts in addition to polyphenol and α, α-trehalose, Sugars such as maltosyl trehalose or pullulan can be included. Moreover, both of these salts and saccharides may be added simultaneously, or one of them may be added alone. Thus, by containing said salts, a strong antibacterial effect is achieved by a synergistic effect, and a softness | flexibility is provided to paper, a nonwoven fabric, or a textile product by containing the said saccharide | sugar.

  The polyphenol used in the present invention is one or more extracts selected from the group consisting of perilla seed extract, grape seed extract, grape leaf extract, soybean extract, apple extract, blueberry extract, and tea extract. The polyphenols from such plant-derived extracts are preferably those containing proanthocyanidins.

  Furthermore, the present invention is an antibacterial agent containing polyphenol and α, α-trehalose as active ingredients, and the antibacterial agent of the present invention may contain the above-mentioned salts or saccharides alone or both.

  According to the present invention, it is possible to continuously impart antioxidant, antibacterial and deodorant properties to paper, non-woven fabric or textile products, and the paper, non-woven fabric or textile products of the present invention are highly safe and excellent. Antioxidant, antibacterial, and deodorant properties. For example, in the case of an antibacterial sheet that is one of the paper, non-woven fabric, or textile product of the present invention, food such as meat pieces wrapped in the antibacterial sheet is oxidized or spoiled. Can be achieved, and food freshness retention can be achieved. In addition, when applied to medical relations such as medical sheets, the paper, non-woven fabric or textile product of the present invention is suitable for at least many types of pathogenic bacteria such as Escherichia coli, Pseudomonas aeruginosa, Salmonella, Staphylococcus aureus, and Vibrio. Since it exhibits excellent antibacterial properties, it is extremely effective in preventing secondary infections such as nosocomial infections.

  The paper, nonwoven fabric or fiber product of the present invention contains polyphenol which is a plant-derived extract and α, α-trehalose.

  α, α-trehalose is a non-reducing and stable carbohydrate in which two glucoses are bound together by α, α-1,1. The α, α-trehalose used in the present invention may be a commercially available high-purity α, α-trehalose hydrous crystal, high-purity α, α-trehalose anhydrous crystal or the like, regardless of its origin. As such α, α-trehalose, for example, there is a high-purity α, α-trehalose 2-containing crystal product (Hayashibara Corporation, registered trademark “Treha”) sold by Hayashibara Corporation.

Paper, nonwoven fabric, the amount of trehalose contained in the textile product has no effect is too small, too large a paper, since the nonwoven fabric, the fiber product becomes hard, usually 1.0 g / m ² paper for nonwoven or textile product range to 10 g / ^{m 2,} more ^{preferably, 3.0g / m 2 ~7.0g / m} 2 range, and more preferably preferably about 5.0 g / ^{m 2.}

  Polyphenol is a general term for a group of substances including flavonoids, tannins, chlorogenic acid, gallic acid, ellagic acid, phenolic acid, etc., and plant pigments such as anthocyanin, rutin, hesperidin, naringin, etc. It is said that there are over 8,000 substances. Examples of polyphenols used in the present invention include polyphenol-containing plant extracts such as tea extract, perilla seed extract, grape seed extract, grape leaf extract, soybean extract, apple extract, and blueberry extract. be able to.

  The polyphenols preferably contain anthocyanins, that is, anthocyanins that are anthocyanin chromophores, or proanthocyanidins that form a condensate or multimer of these anthocyanidins. It is preferably a plant-derived extract that contains a large amount, and examples thereof include a grape seed extract and a grape leaf extract.

  The plant-derived extract can be obtained by extracting each plant material with water or a solvent such as methanol, ethanol, propanol, acetone, or a mixed solution of water and these solvents. A commercially available product can also be used. Examples of such commercially available products include “polyphenone” (trade name, manufactured by Mitsui Norin), a polyphenol extracted from green tea, “leuco select” (trade name, manufactured by Indena), a polyphenol derived from grapes, and Kravi. Nord (trade name, manufactured by Kikkoman Corporation) and the like can be mentioned. In addition, proanthocyanidins as a component of polyphenol can be quantified by extracting the extract by high performance liquid chromatography (HPLC, for example, SupelcoSil LC-18 column) or gel permeation chromatography (GPC, for example, PL gel column). In addition, the content of proanthocyanidins is preferably 30% by weight or more, particularly preferably 90% by weight or more, based on the total polyphenols.

The amount of polyphenol contained in the paper, non-woven fabric, and fiber product of the present invention is ineffective if the amount of polyphenol is too small, and if it is too large, the paper, non-woven fabric, and fiber product are colored, so the amount of polyphenol is that of proanthocyanidins. can not be determined unconditionally by content, usually the amount of proanthocyanidins, paper, a range of 10mg ^{/ m 2} ~500mg ^/ m 2 with respect to the nonwoven fabric or textile, preferably 30mg ^/ m 2 ~350mg ^/ It is preferable to adjust the amount of polyphenol to be contained so as to be in the range of m ² .

In addition to the above α, α-trehalose and polyphenol, the paper, non-woven fabric, or fiber product of the present invention is salt or salt contained in seawater (for example, magnesium chloride, potassium chloride, other mineral salts, etc.) Alternatively, salt such as salt can be further blended using seawater as it is. In addition, although normal seawater can be used as said seawater, it is preferable to use deep seawater from the point that the content of a mineral component is high and there is little contamination with various germs and other substances. By blending these salts, an extremely strong antibacterial action synergistic with the antibacterial action of α, α-trehalose and polyphenol is exhibited. In this case, the amount of polyphenol can be further reduced, and sufficient antibacterial properties are achieved when the amount of polyphenol is 200 mg / m ² or less.

Paper, the amount of salt or sea water contained sodium chloride, seawater blending the nonwoven or textile product, usually in terms of salinity paper, nonwoven or textile range 100mg ^{/ m 2} ~3000mg ^/ m 2 with respect to , preferably about 200mg ^{/ m 2} ~1500mg ^/ m 2 are preferred.

  Moreover, sugars such as maltosyl trehalose and pullulan can be blended in the paper, non-woven fabric or fiber product of the present invention as an additive. Thereby, it can prevent that paper, a nonwoven fabric, and a textile product produced by mix | blending (alpha), (alpha) -trehalose become hard. This is particularly effective when applied to sheets, sheets, and the like. Examples of the maltosyl trehalose and pullulan used include “Hellodex” (Hayashibara Biochemical Laboratories, Inc.) and Hayashibara Co., Ltd., which are mainly composed of maltosyl trehalose sold by Hayashibara Shoji Co., Ltd. There are “Pull Run” (product name) sold by Shoji, and these can be used.

  The amount of maltosyl trehalose or pullulan to be blended is usually 0.5% to 50% by weight of α, α-trehalose, more desirably 5% to 10% by weight. By blending these amounts, The object (giving flexibility) is achieved.

  In the paper, non-woven fabric or fiber product of the present invention, there is no particular limitation on the target paper, non-woven fabric, or fiber, and any of those derived from natural fibers or synthetic fibers can be used.

  The antioxidant / antibacterial agent or deodorant formed by blending the above components may be at least attached to paper, non-woven fabric, or fiber. Therefore, any antioxidant / antibacterial agent, The method of attaching the odorant is not particularly limited, and various methods such as a conventionally known printing method, impregnation method, spray method, pad method, and coating method are widely employed. More specifically, paper, non-woven fabric, or fiber containing polyphenol and α, α-trehalose, and if necessary, an aqueous solution containing salts and / or saccharides by any method such as dipping, spraying, putting or coating. After the treatment, there is a method of removing the liquid as necessary and then drying. Preferable examples include an impregnation method and a gravure coater method.

  The conditions for the impregnation festival are not particularly limited, and can be appropriately selected according to the material of the fiber sheet to be impregnated and the application application.

  Moreover, as long as polyphenol and α, α-trehalose are contained in such a range, the application pattern of polyphenol and α, α-trehalose is not particularly limited, and may be applied to the entire paper, nonwoven fabric, or fiber, Moreover, it may be applied intermittently, such as in the form of dots, broken lines, or crushed.

  The paper, non-woven fabric or textile product of the present invention has at least excellent antibacterial properties against pathogenic bacteria such as Escherichia coli, Pseudomonas aeruginosa, Salmonella, Staphylococcus aureus and Vibrio, and is resistant in an environment suitable for bacterial growth. Hygiene products that require oxidation, antibacterial properties and deodorant properties such as medical sheets (for example, disposable sheets for patients), medical coverings, bandages, medical gauze, adhesive bandages, masks, paper towels, diaper sheets, Panty sheets, sweat pads, sanitary napkins, bed sheets, breast milk pads, incontinence pads, diapers and other sanitary products, air filters, shoe sole materials, pet toilets, fresh fish, fish fillet drip absorption sheets, duties It can be used for a wide range of antioxidant / antibacterial and deodorant applications such as antibacterial / deodorant sheets in refrigerators.

  Further, the present invention is an antibacterial agent containing the above polyphenol, α, α-trehalose and, if necessary, the above-mentioned salts or saccharides alone or both as active ingredients, usually an aqueous solution or ethanol. It is provided in the form of an aqueous solution containing water-soluble solvent or water or an aqueous dispersion. As described above, the antibacterial agent of the present invention can impart antibacterial properties by impregnating paper, non-woven fabric, or fiber products, as well as other products such as plastics, metals, ceramics, and wood products. In contrast, antibacterial properties can be imparted by impregnation, spraying or coating.

  Hereinafter, the present invention will be described in detail by way of examples, but the present invention is not limited thereto.

Example 1
Proanthocyanidin content of 300 mg / m per nonwoven as antibacterial and antioxidant containing plant-derived water-soluble extracted polyphenols (derived from grape seeds, 95% by weight of proanthocyanidins, “Leuco Select”, manufactured by Indena) ^2. Two types of aqueous solutions in which polyphenol (proanthocyanidin) and trehalose are dissolved in distilled water so that trehalose is 5 g / m ² , and the content of proanthocyanidins is 200 mg / m ² and trehalose is 5 g / m ^2. After each was soaked with a mesh nonwoven fabric (50 g / m ² basis weight), it was dried in a hot air dryer at 120 ° C. for 2 hours to produce the antioxidant / antibacterial and deodorant sheets of the present invention.

  The obtained anti-oxidation / antibacterial and deodorant sheets were stored at room temperature for 90 days, and then evaluated by applying the JIS standard for antibacterial processed products and the test method for fiber products (JIS L1902; 2002). Specifically, it is as follows.

[Test bacterial strain]
Staphylococcus aureus (S. aureus ATCC 25923)
E. coli ATCC 25922
Salmonella (S. typhimurium ATCC 14028)
Pseudomonas aeruginosa (P. aeruginosa ATCC 27853)
[Pre-culture of test bacteria]
Nutrient medium shaking culture 37 ± 1 ℃, 2 ± 0.5hr
[Inoculum count]
1 ± 0.3 × 10 ⁵ / ml
[Bacteria suspension]
1 / 20NB: Nutrient medium diluted 20 times with purified water [test piece]
18 x 18mm square 0.4g
Control: Antibacterial unprocessed product [test specimen culture]
Drop 0.2 ml of bacterial solution on the test piece 35 ± 1 ℃ 18 hours culture [Conditions for establishing the test]
The ratio of the initial bacterial count of the control or unprocessed sample to the bacterial count after culture is 1.5 or more in logarithmic value [Test method]
10 μl of a bacterial solution adjusted to 1 to 3.0 × 10 ⁸ cells / ml with a standard bacterial turbidity solution was dropped and mixed in a 10 ml SCD medium, 200 μl was dropped onto a test piece, and cultured in a 37 ° C. incubator for 18 hours. . After completion of the culture, 20 ml of PBS (−) (phosphate buffer) was added, and after 2 minutes of shaking (vortex), measurement was carried out using an SCD agar medium. In addition, it tested similarly using unprocessed cloth as control.

The test was performed on four sheets at a time, and this was repeated twice. Tables 1 to 4 show the viable cell counts of various bacteria by sheet after 18 hours for Staphylococcus aureus, Escherichia coli, Salmonella, and Pseudomonas aeruginosa, respectively. In addition, the number of bacteria in the table is represented by the amount of bacteria in 20 ml of PBS (−). Moreover, the value shown as an average is calculated | required from the test result repeated twice each.

  From the above results, the antioxidant / antibacterial and deodorant sheet of the present invention suppresses the growth and proliferation of at least four types of bacteria, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Salmonella, and exhibits excellent antibacterial properties. I understood that.

Example 2
According to the method described in Example 1, the content of proanthocyanidins was 300 mg / m ² , trehalose was 5 g / m ² , antioxidant / antibacterial and deodorant sheets were prepared, and the deodorization test was performed.

  Evaluation of the deodorizing action was performed by measuring the amount of total volatile aldehyde which is a component of fish odor. Specifically, it is as follows.

[Measuring method]
A commercially available salmon fillet is wrapped in a sheet, sealed and allowed to stand at room temperature for 24 hours / 48 hours, then the sheet is removed and the fillet is minced. Fill a 20 ml Bayer bottle with 5 g (three samples each), add 5 ml of deionized water, and seal and mix with a butyl rubber stopper. The mixture was heated at 100 ° C. for 15 minutes and then naturally cooled, and the volatile aldehyde component was analyzed by capillary GLC (heated at 80 ° C. for 10 minutes and 1 ml of headspace gas was measured). As analysis conditions, TC_FFAP (capillary column 0.53 mm × 30 m, film thickness 1.0 μm, manufactured by GL Sciences Inc.) was used as a column, and detection was performed with a flame ion detector.

  In addition, it tested similarly using unprocessed cloth as control.

  The measurement result of volatile aldehyde is shown in FIG. In FIG. 1, the bar graph shows the total amount of volatile aldehydes, and each aldehyde constituting the components shows acetaldehyde, propanal, butanal, pentanal, 1-hexanal, heptanal, and 1-octanal in order from the left.

  As a result of the above, the total amount of volatile aldehydes is about 0.3 μg / g less than the control of the antioxidant / antibacterial and deodorant sheets of the present invention under any stationary conditions, and suppresses the generation of volatile aldehydes. The deodorizing effect was confirmed.

Example 3
In accordance with the method described in Example 1, the proanthocyanidin content was 100 mg / m ² , the trehalose content was 5 g / m ² , and the sodium chloride content was 1000 mg / m ² , and proanthocyanidins, trehalose and salt Containing sheets (denoted as “P + T + N”), sheets containing proanthocyanidins and trehalose (denoted as “P + T”), sheets containing only salt or proanthocyanidins (denoted as “N” and “P”, respectively) Antioxidant / antibacterial and deodorant sheets were produced from unprocessed cloth sheets not containing these components (indicated as “blank”), and a vivid color retention test was conducted. Specifically, it is as follows.

[material]
Thawed meat slices (about 100 g) for bigeye tuna sashimi were used in the Pacific Ocean and processed into a fence at Kochi Port.

[Test method]
Each sashimi-thaw meat piece (about 100 g) is wrapped in a sheet cut to a size of 20 × 25 cm, and is further put in a polyethylene bag with a chuck, arranged in a metal tray, and set to 10 ± 0.5 ° C. Stored in incubator. The fluorescent lamp in the incubator was continuously turned on. Immediately before storing each piece of meat in an incubator (0 hour), it was taken out every 24 hours after storage, and color difference measurement with a color difference measurement device and photography with a digital camera were performed. In the color difference measurement, three portions of the meat pieces were measured, and averages of L value, a value, and b value were obtained. The photo was taken at a shooting distance of 30 cm (fixed) using an indoor fluorescent lamp as a light source against a background of high-quality cosmos paper.

[Evaluation methods]
Paying attention to the change of the a value measured with the color difference measuring device, the a value for each elapsed time with respect to the a value immediately before storage in the incubator of each piece of meat was expressed as a percentage, and the change of each numerical value was compared. Moreover, the photograph of each piece of meat was compared by visual observation for every elapsed time.

  As a control, a test was conducted in the same manner as a test meat piece using a piece of meat that was simply wrapped in a polyethylene bag with a chuck without being wrapped in a sheet (denoted as “no treatment”).

Table 5 shows color difference a values obtained by the color difference measuring apparatus. The meanings of “P + T + N” and “P + T” in the table are as described above.

  Moreover, the graph showing the variation | change_quantity for every elapsed time with respect to 0 value a value was shown in FIG. The a value indicates a change from green to red of the measurement object, and the red element increases as the numerical value increases in the positive direction. Tuna meat pieces are bright red to vermilion just before the test. It can be seen that the decay of the meat progresses over time, the color changes from black to brown and the red element of the meat piece is lost.

  From the above results, the antioxidant / antibacterial deodorant sheet (P + T or P + T + N) of the present invention has a change amount of about 40% after 96 hours, no treatment or blank, or proanthocyanidin or salt. It was confirmed that the amount of change was smaller than that of the single-processed sheet, and the effect of keeping a fresh color was obtained.

  At this time, the photos of the meat pieces were wrapped and stored in the antioxidant / antibacterial and deodorant sheet (P + T) of the present invention, and in the case of no treatment, immediately before storage (0 hour) and when 48 hours passed. The states are shown in FIGS. In the figure, a and b are the cases when stored with a sheet containing proanthocyanidins and trehalose, a is the one immediately before storage, and b is the one when stored for 48 hours. In addition, c and d are cases where the sheet is not wrapped in a sheet but only put in a polyethylene bag with a chuck, c is immediately before storage, and d is when 48 hours have elapsed.

  According to FIG. 3, even when 48 hours have passed, it can be seen that the meat pieces wrapped with the antioxidant / antibacterial and deodorant sheets of the present invention clearly retain a fresh color.

Example 4
Next, changing the compounding amount of proanthocyanidins, trehalose, and salts to prepare an aqueous solution in which these are dissolved, using a coater & laminator (Kochi Prefectural Paper Industry Technology Center, manufactured by Kawanoe Kikai Co., Ltd.) (SP8750, basis weight 50g / m ² , manufactured by Sansho Paper Industry Co., Ltd.) by gravure coater method (drying temperature 110-120 ° C, production rate 6m / min) to create antioxidant / antibacterial and deodorant sheets And the antibacterial property of the obtained sheet | seat was examined, and the result was shown to Tables 6-10.

  Antibacterial properties were evaluated in the same manner as in Example 1. The test was performed on three sheets at a time, and this was repeated once or twice. Moreover, the value shown as an average is calculated | required from each test result.

In addition, the number of bacteria related to antibacterial properties is expressed in colony forming units (CFU / ml), and “P”, “T”, and “N” in the treated sheet represent proanthocyanidins, α, α-trehalose, shows the salt, the numerical values set appended to then indicates the amount per sheet 1 m ^2.

  The test was performed on the following bacterial strains:

Pseudomonas aeruginosa (P. aeruginosa ATCC 27853)
Salmonella (S. enteritidis IFO 3313)
Vibrio (V. parahemolyticus IFO 12711)
Methicillin resistant Staphylococcus aureus (MSRA-clinical isolate)
Enterohemorrhagic E. coli O157 (enterohemorrhagic E. coli O157 H1-clinical isolate)

  From the above, the antioxidant / antibacterial and deodorant sheet of the present invention inhibits the growth and proliferation of at least five types of bacteria: Pseudomonas aeruginosa, Salmonella, Vibrio, methicillin-resistant Staphylococcus aureus, and enterohemorrhagic Escherichia coli O157. It was found that it exhibits excellent antibacterial properties.

Furthermore, from this test, by combining proanthocyanidins, α, α-trehalose and salts (eg, salt), rather than the antibacterial properties of the combination of 300 mg / m ^{2 of} proanthocyanidins and α, α-trehalose of Example 1 It can be seen that a superior amount of proanthocyanidins, ie, 100 mg / m ² or less, exhibits excellent antibacterial effects. That is, it was found that a stronger antibacterial effect can be obtained by the synergistic effect of proanthocyanidins and salts (for example, salt). In addition, in Tables 6-10, the synergistic effect by this salt is that the treatment sheet containing 1 g of sodium chloride in addition to these components is added to the treatment sheet of 100 mg of proanthocyanidins and 5 g of α, α-trehalose. However, it can be understood from the fact that it is at least 10 ² to 10 ³ or less.

It is a graph which shows the measurement result of the volatile aldehyde which generate | occur | produces, when a salmon fillet is wrapped with a sheet | seat, airtightly, and it is left to stand at room temperature for 24 hours and 48 hours. In the figure, the bar graph indicates the total amount of volatile aldehydes, and the constituent aldehydes indicate acetaldehyde, propanal, butanal, pentanal, 1-hexanal, heptanal, and 1-octanal in order from the left. It is a graph which shows the variation | change_quantity of the a value measured with the color difference measuring apparatus when wrapping the thawed meat piece of a tuna with a sheet | seat, airtight, and preserve | saved at 10 degreeC. The a value indicates a change from green to red of the measurement object, and it can be seen that the decay of the meat piece proceeds with time and the red element of the meat piece is lost. It is a figure which shows the state of the meat piece of the case where the thawed meat piece of a tuna is wrapped with the antibacterial sheet of this invention, and the case of no processing. In the figure, a and b are antibacterial sheets of the present invention, showing the state immediately before storage (a) and after the lapse of 48 hours (b), respectively, d and c are not wrapped in a sheet, but in a polyethylene bag with a chuck. This is the case of just putting it in, and shows the state immediately before storage (c) and after 48 hours (d), respectively.

Claims (4)

Polyphenol containing proanthocyanidins, alpha, and α- trehalose, sodium chloride, salts contained in seawater or with any of the seawater, to that antimicrobial paper containing as an active ingredient, a non-woven or textile, pro salt content of anthocyanidins is ^{100mg / m 2 ~500mg / m 2} , α, the content of α- trehalose is ^{1.0g / m 2 ~10.0g / m 2} , which contained sodium chloride, seawater, or the content of seawater, the antimicrobial is 100mg ^{/ m 2} ~3000mg ^/ m 2 as the concentration of salts paper, nonwoven or textile. The antibacterial paper, non-woven fabric or textile product according to claim 1, further comprising maltosyl trehalose or pullulan. The antibacterial paper, non-woven fabric or textile product according to claim 2 , wherein the content of maltosyl trehalose or pullulan is 0.5 to 50% by weight of α, α-trehalose. A polyphenol containing proanthocyanidins , α, α-trehalose, salt, salt contained in seawater, or seawater for producing the antibacterial paper, nonwoven fabric or textile product according to claim 1 ; antibacterial agents containing as an active ingredient.