JP3665498B2 - Medical jelly in a bag - Google Patents

Description

[0001]
BACKGROUND OF THE INVENTION
The present invention relates to a medical jelly encapsulated in a bag-like container convenient for internal use.
[0002]
[Prior art]
Considering the future medical care in Japan, there are various problems in the medical care of an aging society, and now it is indispensable to develop a preparation for the elderly. Jelly preparations are easy to take for elderly patients, especially patients with dysphagia, and are preparations that meet this purpose.
[0003]
For the administration of this jelly agent, so far, the jelly agent has been carried out by in-hospital prescription. For example, a method of administering the jelly agent to the patient's mouth with a spoon or the like is generally performed.
[0004]
[Problems to be solved by the invention]
However, when a jelly agent is administered to the patient with dysphagia, especially a bedridden patient, the patient may swallow it immediately without chewing, and it may be swallowed, exhaled, or the jelly agent may be held in the throat and breathed. There is a risk that it will not be possible.
[0005]
In addition, an administration device such as a spoon is required in addition to the container that contains the jelly, which makes it difficult to take when taking the device on the go, especially when you forget the administration device on the go There are also problems such as.
[0006]
In order to solve such problems, the jelly agent is stored in a film-like bag-like container that can be heat-welded, and the jelly agent is extruded from the bag-like container by unsealing and pressing the barrel, It may be possible to take the jelly directly from the container. In this way, an administration device or the like can be dispensed with. However, the contents stored in a bag-like container made of heat-weldable film are generally flat in shape and have a small thickness, and it is difficult to say that it is easy to extrude when the jelly agent is used as the contents. In this respect, it lacks convenience.
[0007]
The present invention has been made from the above viewpoints, and provides a containerized medical jelly agent that can be easily administered directly into the mouth from a container in which the jelly agent is stored without using an administration device or the like. The task is to do. It is another object of the present invention to provide a light and compact medical jelly agent that is convenient for carrying.
[0008]
[Means for Solving the Problems]
<Medical jelly agent in a bag-like container of the present invention>
The present invention employs the following configuration in order to solve the above problems.
[0009]
That is, the medical jelly agent in a bag-like container of the present invention (hereinafter sometimes simply referred to as “the jelly agent in a container”) is a stick-like bag formed of a heat-weldable film and sealed inside by heat-welding. A medical jelly encapsulated in a cylindrical container, wherein the container includes a body part, and at least one end and a side part in the longitudinal direction of the body part, and the body part in the longitudinal direction. A portion in which the divided gas is sealed and a portion in which the medical jelly agent is sealed, and the inner pressure in the trunk is equal to or higher than the outer pressure, and the trunk is full, A notch or break line is provided in the vicinity of one end of the portion side where the medical jelly agent in the longitudinal direction of the trunk portion is sealed on the heat seal portion provided on the longitudinal side portion of the trunk portion, and the notch Or by opening the container from the break line A container containing a medical jelly agent characterized in that part is formed.
[0010]
Further, according to the present invention, the notch or break line is provided on the heat seal portion at a position 2 to 5 mm inside from the one end of the portion side where the medical jelly agent is sealed toward the longitudinal direction of the trunk portion. This is a containerized medical jelly characterized by the above. By providing a notch or break line at such a position, the bag-like container can be easily opened from the notch or break line portion, and the jelly agent is not scattered at the time of opening. And after opening, the part by which gas is enclosed is compressed with a finger, and a jelly agent can be smoothly extruded from an opening part, maintaining the shape.
[0011]
As described above, the trunk of the bag-like container used in the present invention has a portion in which a medical jelly agent is sealed and a portion in which gas is sealed. Hereinafter, in this specification, the portion of the body of the bag-like container in which the jelly agent is sealed is referred to as “jelly agent-sealed portion”, and the portion in which gas is sealed may be referred to as “gas-sealed portion”. Also, of the longitudinal ends of the body part, one end on the part side in which the jelly agent is sealed is referred to as a “jelly agent sealed end”, and the other end on the part side in which the gas is sealed is referred to as a “gas sealed end”. There is.
[0012]
The present invention will be described in detail below.
As the bag-like container used in the present invention, a bag-like container formed of a heat-weldable film and sealing the inside of the bag-like container by heat welding is used. Preferable examples of the heat-weldable film include polyamides such as nylon, polyesters such as polyethylene terephthalate, polyethylenes and polypropylenes, and silica-deposited polyethylene terephthalate. The film forming the bag-like container in the present invention may be a single layer or multiple layers. In the case of a multilayer, an aluminum foil may be used as an intermediate layer or an outer layer from the viewpoint of airtightness. Specific examples of the film forming the bag-like container include laminated films of polyethylene / aluminum foil / polypropylene, polyethylene / silica vapor-deposited polyethylene terephthalate / polyethylene terephthalate, polyethylene / nylon / polyethylene, and particularly preferably polyethylene / silica. Examples include vapor-deposited polyethylene terephthalate / polyethylene terephthalate. The film which forms a bag-like container can be selected according to the medical jelly which is the contents. The thickness of the film may be adjusted as appropriate as long as it does not rupture when the trunk is expanded, but it is preferably 30 to 100 μm, particularly preferably 50 to 80 μm.
[0013]
Moreover, the said bag-shaped container is provided with the rod-shaped trunk | drum part with which the medical jelly agent and gas are enclosed, and the heat seal part formed by heat welding. The heat seal portion may be provided at both ends in the longitudinal direction of the rod-like bag-like container so that the inside of the bag-like container can be sealed, but is provided at least at one end of the portion side where the jelly agent is sealed. In addition, the heat seal part is also provided at the side part in the longitudinal direction of the container body part in order to provide a notch or a breaking gland for opening the container. That is, the heat seal portion is provided in two directions, one in the longitudinal direction and one side in the longitudinal direction of the container body, but in three directions in both the longitudinal direction and one side and one longitudinal side and both sides. It can also be provided in a total of four directions on both ends in the longitudinal direction and on both sides of the side portion.
[0014]
The container-containing jelly agent of the present invention is in a state where the body portion is full, and the medical jelly agent as a content is flat even when stored in a bag-like container formed of a heat-weldable film. The medical jelly agent can be smoothly pushed out from the bag-like container. In the present invention, “the state in which the body portion is full” means that when a molten jelly agent is added and pressurized, the body section in a direction perpendicular to the longitudinal direction of the body portion changes from a circular shape to an elliptical shape. It means a state that The ratio of the length of the major axis to the minor axis of the circular to elliptical trunk section is preferably 1: 1 to 2: 1. Moreover, it is preferable that the trunk | drum of the bag-shaped container in the medical jelly agent with a container of this invention is rod-shaped, and the ratio of the length of the longitudinal direction of a trunk | drum and the length of a transversal direction is 15: 1-2. : About 1 is preferable. The length in the longitudinal direction and the length in the short direction of the trunk can be appropriately changed depending on the amount of contents to be enclosed. For example, when the jelly agent to be sealed is changed to 3 g, 5 g, etc., the width of the container and the length of the container can be appropriately changed correspondingly.
[0015]
In addition, for the convenience of providing a heat seal portion at the end in the major axis direction of the barrel portion in the rod-like barrel portion having a circular to elliptical cross section as described above, a direction orthogonal to the major axis direction at this end portion However, in the present invention, such a cross section is also included as having a cross section from a circular shape to an elliptical shape.
[0016]
It is preferable that a medical jelly agent and a gas are sealed in the body, and the internal pressure in the body is made higher than the external pressure so that the body is full. The internal pressure is preferably such that the bag-like container is not ruptured, and the pharmaceutical jelly encapsulated inside before opening is not crushed by normal handling, for example, pressing it with a human hand at room temperature. Specifically, the internal pressure in the body portion is 1.05 to 1.5 of 20 ° C., preferably an external atmospheric pressure (hereinafter referred to as 1 atm unless otherwise specified). It is preferable that the pressure is 1.01 to 1.2 times the outer pressure, more preferably 1.02 to 1.05 times the outer pressure, and particularly preferably 1.02 to 1.05 times the outer pressure. Examples of the gas sealed in the body part include air, nitrogen gas, argon, and helium. As described above, the inner air pressure in the body portion of the present invention is preferably higher than the outer air pressure, but may be equal to the outer air pressure.
[0017]
In the bag-like container used in the present invention, the heat seal part is provided at one end and the side part of the part side in which the jelly agent in the longitudinal direction of the container is enclosed as described above. And it is preferable to provide the notch or breaking line for opening on the heat seal part provided in the side part of the container. By opening the bag-like container from a notch or break line provided on the heat seal part, the opening part can be easily formed, and the convenience of use is further improved.
[0018]
The position at which the notch or break line is provided on the heat seal portion provided on the side of the container is preferably provided so that it can be opened in a direction perpendicular to the long axis direction of the rod-like bag-like container. Further, when the bag-like container is opened from the notch or break line, the notch or break line is provided at the position where the vicinity of the jelly-agent-sealed end of the trunk is opened. It is preferable that the position where the notch or break line is provided is provided on the heat seal portion at a position 2 to 5 mm inside from the jelly agent-filled end in the longitudinal direction of the body portion. If it is opened at the part near the jelly agent enclosure end, the container can be opened without dirtying the hand, and the pressure of the enclosed gas is used by compressing the gas enclosure part with the finger in the container. Thus, the jelly agent can be extruded smoothly while maintaining its shape. In particular, it is useful when extruding a jelly agent having a weak gel strength.
[0019]
As the medical jelly agent enclosed in the bag-like container, those generally used as medical jelly agents can be applied, but preferably, gastrointestinal drugs for internal use, cold medicines, antibacterial agents, OTC internal preparations A jelly agent such as an aluminum / magnesium antacid and an antibacterial agent is preferably used.
[0020]
In the container-containing jelly agent of the present invention, the amount of the medical jelly agent enclosed in the bag-like container can be the same as a single dose for the patient. If it does in this way, a user can do the right prescription without making a mistake in one dose. Although it depends on the kind of the medical jelly agent, the storage amount is preferably 0.3 to 15 g, particularly preferably 0.5 to 5 g.
[0021]
Further, in the jelly agent in the container of the present invention, the ratio of the jelly agent to be encapsulated and the gas is not particularly limited, but the ratio of both is a volume ratio, preferably 10: 1 to 5: 1, and further Preferably it is 10: 3 to 3: 2. Further, when the amount of the jelly agent contained is small, it is preferable to make the internal pressure higher than the external pressure in order to push out the jelly agent while maintaining its shape using the pressure of the enclosed gas.
[0022]
The bag-like container used in the present invention is formed of a film that can be heat-welded as described above, and the storage amount can be the same as a single dose for a patient. The jelly preparation can be light and compact.
[0023]
<The manufacturing method of the medical jelly with a bag-shaped container of this invention>
The method for producing the medical jelly in a bag-like container of the present invention is not particularly limited as long as it can be sealed in a state where the trunk portion is inflated. For example, a bag-like container having an opening is available. Inside, the medical jelly agent in a molten state is filled, the opening is sandwiched between two bag-shaped rolls that are in contact with the circumference, and the roll is rotated downward so that the inside of the trunk of the bag-shaped container The inner pressure inside the body is made higher than the outside pressure by squeezing the gas, and the body is inflated, then the film on the compressed side of the bag-like container is sealed by thermal welding, and then cooled to medical jelly And a method of solidifying the agent.
[0024]
In order to swell the body part, after filling the medical jelly agent, the body part may be swelled by sealing with compressed air. Moreover, it can also be set as the state which filled the trunk | drum by filling the bag-shaped container with the medical jelly agent and performing the process of sealing a bag-shaped container by heat welding in a pressurization chamber. Alternatively, the bag-shaped container may be made into a rod shape in advance and filled with a molten medical jelly to expand the trunk. In addition, the method of heat welding, the shaping | molding of the bag-shaped container which can become a rod shape when the trunk | drum is expanded, the method of providing a notch or a break line, etc. can be performed in accordance with a normal method.
[0025]
DETAILED DESCRIPTION OF THE INVENTION
Hereinafter, an example of an embodiment of the present invention will be described with reference to the drawings of FIGS.
<Medical jelly agent in a bag-like container of the present invention>
1-5 is a figure which shows an example of the medical jelly agent containing a bag-shaped container of this invention. FIG. 1 is a front view of an example of a medical jelly agent in a bag-like container according to the present invention. FIG. 2 is a side view of an example of the medical jelly agent in a bag-like container of the present invention. FIG. 3 is a plan view of an example of the medical jelly agent in a bag-like container of the present invention. FIG. 4 is a perspective view of an example of the medical jelly agent in a bag-like container of the present invention. FIG. 5 is a perspective view showing an example of the medical jelly containing a bag-like container of the present invention, opened from the notch.
[0026]
In the medical jelly agent 1 in a bag-like container, the medical jelly agent 6 and the gas 7 are enclosed in the bag-like container 2 formed of polyethylene terephthalate / polyethylene terephthalate / polyethylene film made of silica vapor deposition and sealed inside by thermal welding. ing.
[0027]
Further, the bag-like container 2 includes a body portion 3 for storing the medical jelly agent 6 and the gas 7, a jelly agent-sealed end 31, a gas-sealed end 32, and a heat seal portion 40 on the side of the bag-like container 2. The body portion 3 has a rod shape.
[0028]
A medical jelly agent 6 and a gas 7 are sealed in the body 3, the internal pressure in the body 3 is higher than the external pressure, and the body 3 is in a state of being expanded at room temperature.
Further, the notch 50 for opening is provided in the heat seal portion 40 at a position located 3 mm inside from the jelly-agent-sealed end 31 so that the opening can be easily performed. The notch 50 can be opened in a direction orthogonal to the major axis direction of the rod-like bag-like container 2, and when the bag-like container 2 is opened from the notch 50, the portion of the jelly-agent-sealed end 31 is opened in the body 3. It is provided in the position to be.
[0029]
<The manufacturing method of the medical jelly with a bag-shaped container of this invention>
FIG. 6 is a diagram showing an example of a method for producing a medical jelly agent in a bag-like container according to the present invention, which is an example of producing the medical jelly agent in a bag-like container shown in FIGS.
[0030]
A bag-like container 2 having an opening 8a connected to the body portion 3 is filled with a medical jelly agent 6a in a molten state through a jelly agent filling needle 9, and between the two bag-like rolls 10 in contact with the circumferential portion. After sandwiching the opening 8a, rotating the roll 10 downward to compress the air in the body of the bag-like container 2 and making the internal pressure in the body higher than the external air pressure, the body 3 is expanded. The compressed side of the bag-like container is sealed by heat welding, and then cooled to solidify the medical jelly agent, whereby the medical jelly agent 1 in a bag-like container is obtained.
[0031]
【The invention's effect】
The medical jelly agent containing the bag-like container of the present invention can be smoothly extruded while maintaining the shape of the jelly agent using the pressure of the gas in which the medical jelly agent is sealed from the bag-like container. Can be easily administered directly into the mouth. Moreover, the jelly agent in a container of the present invention can be administered into a patient's mouth without using an administration device, and is particularly convenient when going out.
[0032]
Moreover, since the internal pressure of the trunk portion is higher than the external pressure and the trunk portion is full, the jelly agent is not easily crushed by being stored in a bag-like container formed of a film. Furthermore, when the amount of the medical jelly agent stored is the same as the single dose for the patient, there is an effect that the user can make a correct prescription without making a mistake in the single dose. In addition, the containerized jelly agent of the present invention can be light and compact.
[Brief description of the drawings]
FIG. 1 is a front view of an example of a medical jelly agent in a bag-like container according to the present invention.
FIG. 2 is a side view of an example of a medical jelly in a bag-like container according to the present invention.
FIG. 3 is a plan view of an example of a medical jelly in a bag-like container according to the present invention.
FIG. 4 is a perspective view of an example of a medical jelly in a bag-like container according to the present invention.
FIG. 5 is a perspective view showing a state where the bag is opened from the notch in an example of the medical jelly agent in a bag-like container according to the present invention.
FIG. 6 is a diagram showing an example of a method for producing a medical jelly agent in a bag-shaped container according to the present invention.
[Explanation of symbols]
1 ·· Medical jelly agent in a bag-like container 2 · Bag-like container 3 ·· Body 31 ·· Jill agent enclosing end 32 ·· Gas enclosing end 40 and 40a ·· Heat seal portion 50 ·· Notches 6 and 6a .. Medical jelly agent 7 .. Gas 80.. Opening 8 a formed by opening from notch.. Opening 9 for filling with jelly agent. Jelly filling needle 10.

Claims (2)

A medical jelly agent formed in a stick-shaped bag-like container formed of a heat-weldable film and sealed inside by heat-welding, wherein the container has a body part and at least one end in the longitudinal direction of the body part And a heat seal portion on each of the side portions, and the body portion includes a portion in which a gas divided in the longitudinal direction is enclosed and a portion in which a medical jelly agent is enclosed, and the internal pressure in the body portion is The torso is full or equal to or higher than the outside air pressure,
On the heat seal portion provided on the longitudinal side of the trunk, a notch or break line is provided in the vicinity of one end on the side where the longitudinal medical jelly agent is enclosed, A medical jelly agent in a container, wherein an opening is formed by opening the container from a notch or a broken line. The notch or break line is provided on a heat seal portion at a position 2 to 5 mm inward from one end on the side where the medical jelly agent is sealed in the longitudinal direction of the trunk portion. Item 10. A medical jelly preparation according to item 1.

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